Although there is not one specific sign or symptom related to alcoholic hepatitis(AH),a constellation of symptoms and signs can help make the diagnosis of AH with reasonable accuracy.Documentation of chronic and activ...Although there is not one specific sign or symptom related to alcoholic hepatitis(AH),a constellation of symptoms and signs can help make the diagnosis of AH with reasonable accuracy.Documentation of chronic and active alcohol abuse is paramount in making a diagnosis of AH.Clinical presentation after abstinence for more than 3 m should raise doubts about the diagnosis of AH and dictate the need for considering other causes of liver disease,decompensation of alcoholic cirrhosis,sepsis and malignancy as the cause of patient's clinical profile.展开更多
In the present study, the authors selected points according to differentiation of symptoms and signs and applied filiform needles to treating 40 cases of hiccup who had tried treatment with Western and Chinese drugs b...In the present study, the authors selected points according to differentiation of symptoms and signs and applied filiform needles to treating 40 cases of hiccup who had tried treatment with Western and Chinese drugs but without any effect and achieved satisfactory results. After acupuncture treatment, 34 cases (85 %) were cured, 4 (10 %) improved markedly and 2(5 %) improved, with total effective rate of 100 %.展开更多
Motor symptoms are cardinal clinical features of Parkinson’s disease (PD). Progress in drug therapy and rehabilitation has been presenting beneficial effect for motor symptoms. However, non-motor symptoms and signs i...Motor symptoms are cardinal clinical features of Parkinson’s disease (PD). Progress in drug therapy and rehabilitation has been presenting beneficial effect for motor symptoms. However, non-motor symptoms and signs in PD have been accumulated growing attentions and its amelioration may also give beneficial effect for PD patients’ and their care givers’ quality of life. In this mini-review, I overviewed non-motor symptoms and signs in PD.展开更多
Background: Herbal dentifrices appear to have become an attractive alternative for some consumers and its use has gained appreciable acceptance in Nigeria. This could be partly due to the perception that herbal toothp...Background: Herbal dentifrices appear to have become an attractive alternative for some consumers and its use has gained appreciable acceptance in Nigeria. This could be partly due to the perception that herbal toothpastes like other herbal products are “natural”, devoid of chemicals and therefore superior to regular toothpastes. Aggressive advertisement of the products may also contribute to this new trend. Mucosal symptoms such as glossitis and intolerance to spicy foods seen in patients attending the oral diagnosis clinic are usually associated with anaemia and nutritional deficiency states. The disturbing trend of an increasing number of patients presenting with such oral mucosal symptoms associated with the use of herbal dentifrices prompted this study. This trend was observed in two isolated oral medicine clinics. Objective: To sensitize oral health, allied professionals and consumers on the possible adverse effects of regular use of some herbal dentifrices sold in Nigeria. Materials and Methods: Routine patients of two oral medicine clinics in Lagos, namely the Randle General Hospital and the Lagos University Teaching Hospital who complained of some adverse mucosal signs and symptoms following the regular use of two identified herbal toothpastes made up the study population. The study was conducted between April 2010-April 2011. A detailed history and examination was carried out on these patients and clinical photographs of oral signs observed was taken in consenting patients. Data analysis was done using the Epi-info 6 software. P values ≤ 0.05 was considered statistically significant and data was presented in table format. Results: A total of 45 patients, 9 (20%) males and 36 (80%) fe-males were seen. The age range of patients was 14 - 78 years;mean age 45.5 ± 14.9 years. The duration of use of herbal dentifrices ranged from 2 weeks - 84 months (mean 24 ± 11.5 months). Oral signs and symptoms seen include, burning mouth and peppery sensation, mucosal erythema, lichenoid reaction, xerostomia, loss of taste sensation, angio-oedema and oral and peri-oral pigmentation. In many patients, resolution of symptoms was progressive within 2 weeks of withdrawal of the herbal toothpaste and its replacement with a conventional fluoride toothpaste. Most of the patients however required further treatment. A statistically significant association was found between the use of the identified herbal dentifrices and the following mucosal signs and symptoms namely, burning mouth and peppery sensation ,loss of taste sensation, soreness, erythema and lichenoid straie (p value ≤ 0.05). There was no statistically significant association between the use of herbal toothpaste and mucosal signs and symptoms of xerostomia, angular cheilitis, mucosal itching, angio-oedema and numbness (p value > 0.0.5) Conclusion: The regular use of the herbal dentifrices identified in this study can result in oral signs and symptoms affecting taste , nutrition, aesthetics and general oral physiology in some consumers. These findings suggest that further long term clinical trials need to be conducted on the herbal dentifrices to identify the noxious agents causing these symptoms. The formulation and use of these dentifrices need to be standardized and regulated. There is also a need to formulate a treatment protocol for these patients.展开更多
Physical examination signs have not been well studied,and their accuracy and reliability in diagnosis remain unknown.The few studies available are limited in that the method of performing the sign was not stated,the t...Physical examination signs have not been well studied,and their accuracy and reliability in diagnosis remain unknown.The few studies available are limited in that the method of performing the sign was not stated,the technique used was not standardized,and the position of the appendix was not correlated with imaging or surgical findings.Some appendiceal signs were written in a non-English language and may not have been appropriately translated(e.g.,Blumberg-Shchetkin and Rovsing).In other cases,the sign described differs from the original report(e.g.,Rovsing,Blumberg-Shchetkin,and Cope sign,Murphy syndrome).Because of these studies limitations,gaps remain regarding the signs’utility in the bedside diagnosis of acute appendicitis.Based on the few studies available with these limitations in mind,the results suggest that a positive test is more likely to be found in acute appendicitis.However,a negative test does not exclude the diagnosis.Hence,these tests increase the likelihood of ruling in acute appendicitis when positive but are less helpful in ruling out disease when negative.Knowledge about the correct method of performing the sign may be a valuable adjunct to the surgeon in further increasing their pretest probability of disease.Furthermore,it may allow surgeons to study these signs further to better understand their role in clinical practice.In the interim,these signs should continue to be used as a tool to supplement the clinical diagnosis.展开更多
The aim of this study was to evaluate the incidence and severity of erectile dysfunction (ED) and hypogonadism in 193 men presenting with lower urinary tract symptoms (LUTSs) in the younger (20 - 39 years old) and old...The aim of this study was to evaluate the incidence and severity of erectile dysfunction (ED) and hypogonadism in 193 men presenting with lower urinary tract symptoms (LUTSs) in the younger (20 - 39 years old) and older (40 - 60 years old) age groups depending on the presence of metabolic syndrome (MetS). Triglycerides, glucose and high-density lipoprotein cholesterol, serum total testosterone (TT), sex hormone-binding globulin, prostate-specific antigen, pituitary hormones levels were measured in serum. Standardized criteria (2009) were used to determine the prevalence of MetS. Patients were assessed based on the International Prostate Symptom Score (IPSS) and the IPSS-Quality of Life (IPSS-QoL) for LUTSs and the International Index of Erectile Function (IIEF) for ED. Hypogonadism was determined in accordance with the ISA, ISSAM, EAU, EAA and ASA recommendations. In men with MetS in the younger age group the incidence of ED was 2.4 times higher, and that of low TT level and hypogonadism was 8.4 times higher compared to men without the syndrome. In the older age group, an increased incidence of ED and low TT level in men with MetS compared to men without the syndrome was on the trend level, but the incidence of hypogonadism was for sure higher (by 1.6 times). In conclusion, the study showed that ED and hypogonadism are associated with MetS by a high degree of certainty in young men with LUTSs. In men of the older age group with LUTSs, the presence of MetS is not so clearly associated with ED and hypogonadism due to the fact that the incidence of these urogenital diseases is also high in men without MetS.展开更多
The signing ceremony of strategic cooperation agreement between China Chamber of International Commerce(CCOIC)and Suning Commerce Group Co.,Ltd(Suning)was heldin Beijing on August 23.Chairman of the CCPIT and CCOIC Ji...The signing ceremony of strategic cooperation agreement between China Chamber of International Commerce(CCOIC)and Suning Commerce Group Co.,Ltd(Suning)was heldin Beijing on August 23.Chairman of the CCPIT and CCOIC Jiang Zengwei and chairman of Suning Zhang Jindong attended and witnessed the ceremony.Secretary-General of the CCOIC Yu Jianlong and vice president of展开更多
The representative collective digital signature,which was suggested by us,is built based on combining the advantages of group digital signature and collective digital signature.This collective digital signature schema...The representative collective digital signature,which was suggested by us,is built based on combining the advantages of group digital signature and collective digital signature.This collective digital signature schema helps to create a unique digital signature that deputizes a collective of people representing different groups of signers and may also include personal signers.The advantage of the proposed collective signature is that it can be built based on most of the well-known difficult problems such as the factor analysis,the discrete logarithm and finding modulo roots of large prime numbers and the current digital signature standards of the United States and Russian Federation.In this paper,we use the discrete logarithmic problem on prime finite fields,which has been implemented in the GOST R34.10-1994 digital signature standard,to build the proposed collective signature protocols.These protocols help to create collective signatures:Guaranteed internal integrity and fixed size,independent of the number of members involved in forming the signature.The signature built in this study,consisting of 3 components(U,R,S),stores the information of all relevant signers in the U components,thus tracking the signer and against the“disclaim of liability”of the signer later is possible.The idea of hiding the signer’s public key is also applied in the proposed protocols.This makes it easy for the signing group representative to specify which members are authorized to participate in the signature creation process.展开更多
American Sign Language(ASL)images can be used as a communication tool by determining numbers and letters using the shape of the fingers.Particularly,ASL can have an key role in communication for hearing-impaired perso...American Sign Language(ASL)images can be used as a communication tool by determining numbers and letters using the shape of the fingers.Particularly,ASL can have an key role in communication for hearing-impaired persons and conveying information to other persons,because sign language is their only channel of expression.Representative ASL recognition methods primarily adopt images,sensors,and pose-based recognition techniques,and employ various gestures together with hand-shapes.This study briefly reviews these attempts at ASL recognition and provides an improved ASL classification model that attempts to develop a deep learning method with meta-layers.In the proposed model,the collected ASL images were clustered based on similarities in shape,and clustered group classification was first performed,followed by reclassification within the group.The experiments were conducted with various groups using different learning layers to improve the accuracy of individual image recognition.After selecting the optimized group,we proposed a meta-layered learning model with the highest recognition rate using a deep learning method of image processing.The proposed model exhibited an improved performance compared with the general classification model.展开更多
针对航空母舰飞行甲板上舰载机弹药保障面临的调度效率不高的问题,提出了一种改进灰狼优化(grey wolf optimizer, GWO)算法。根据甲板上多升降机多运输车的场景特点,建立了由多车场出发、向多目标转运的问题模型。融合遗传算法算子交叉...针对航空母舰飞行甲板上舰载机弹药保障面临的调度效率不高的问题,提出了一种改进灰狼优化(grey wolf optimizer, GWO)算法。根据甲板上多升降机多运输车的场景特点,建立了由多车场出发、向多目标转运的问题模型。融合遗传算法算子交叉思想实现了对灰狼种群初始解的初步优化,并通过直线转运路径中间点定义、整数编码、负整数标志分组等方法实现了对GWO算法求解过程的改进。同时,增加了灰狼个体自由狩猎流程,有效克服了结果陷入局部最优和早熟的问题。最终,通过对场景实例的优化求解,验证了所提方法的有效性和可行性。展开更多
文摘Although there is not one specific sign or symptom related to alcoholic hepatitis(AH),a constellation of symptoms and signs can help make the diagnosis of AH with reasonable accuracy.Documentation of chronic and active alcohol abuse is paramount in making a diagnosis of AH.Clinical presentation after abstinence for more than 3 m should raise doubts about the diagnosis of AH and dictate the need for considering other causes of liver disease,decompensation of alcoholic cirrhosis,sepsis and malignancy as the cause of patient's clinical profile.
文摘In the present study, the authors selected points according to differentiation of symptoms and signs and applied filiform needles to treating 40 cases of hiccup who had tried treatment with Western and Chinese drugs but without any effect and achieved satisfactory results. After acupuncture treatment, 34 cases (85 %) were cured, 4 (10 %) improved markedly and 2(5 %) improved, with total effective rate of 100 %.
文摘Motor symptoms are cardinal clinical features of Parkinson’s disease (PD). Progress in drug therapy and rehabilitation has been presenting beneficial effect for motor symptoms. However, non-motor symptoms and signs in PD have been accumulated growing attentions and its amelioration may also give beneficial effect for PD patients’ and their care givers’ quality of life. In this mini-review, I overviewed non-motor symptoms and signs in PD.
文摘Background: Herbal dentifrices appear to have become an attractive alternative for some consumers and its use has gained appreciable acceptance in Nigeria. This could be partly due to the perception that herbal toothpastes like other herbal products are “natural”, devoid of chemicals and therefore superior to regular toothpastes. Aggressive advertisement of the products may also contribute to this new trend. Mucosal symptoms such as glossitis and intolerance to spicy foods seen in patients attending the oral diagnosis clinic are usually associated with anaemia and nutritional deficiency states. The disturbing trend of an increasing number of patients presenting with such oral mucosal symptoms associated with the use of herbal dentifrices prompted this study. This trend was observed in two isolated oral medicine clinics. Objective: To sensitize oral health, allied professionals and consumers on the possible adverse effects of regular use of some herbal dentifrices sold in Nigeria. Materials and Methods: Routine patients of two oral medicine clinics in Lagos, namely the Randle General Hospital and the Lagos University Teaching Hospital who complained of some adverse mucosal signs and symptoms following the regular use of two identified herbal toothpastes made up the study population. The study was conducted between April 2010-April 2011. A detailed history and examination was carried out on these patients and clinical photographs of oral signs observed was taken in consenting patients. Data analysis was done using the Epi-info 6 software. P values ≤ 0.05 was considered statistically significant and data was presented in table format. Results: A total of 45 patients, 9 (20%) males and 36 (80%) fe-males were seen. The age range of patients was 14 - 78 years;mean age 45.5 ± 14.9 years. The duration of use of herbal dentifrices ranged from 2 weeks - 84 months (mean 24 ± 11.5 months). Oral signs and symptoms seen include, burning mouth and peppery sensation, mucosal erythema, lichenoid reaction, xerostomia, loss of taste sensation, angio-oedema and oral and peri-oral pigmentation. In many patients, resolution of symptoms was progressive within 2 weeks of withdrawal of the herbal toothpaste and its replacement with a conventional fluoride toothpaste. Most of the patients however required further treatment. A statistically significant association was found between the use of the identified herbal dentifrices and the following mucosal signs and symptoms namely, burning mouth and peppery sensation ,loss of taste sensation, soreness, erythema and lichenoid straie (p value ≤ 0.05). There was no statistically significant association between the use of herbal toothpaste and mucosal signs and symptoms of xerostomia, angular cheilitis, mucosal itching, angio-oedema and numbness (p value > 0.0.5) Conclusion: The regular use of the herbal dentifrices identified in this study can result in oral signs and symptoms affecting taste , nutrition, aesthetics and general oral physiology in some consumers. These findings suggest that further long term clinical trials need to be conducted on the herbal dentifrices to identify the noxious agents causing these symptoms. The formulation and use of these dentifrices need to be standardized and regulated. There is also a need to formulate a treatment protocol for these patients.
文摘Physical examination signs have not been well studied,and their accuracy and reliability in diagnosis remain unknown.The few studies available are limited in that the method of performing the sign was not stated,the technique used was not standardized,and the position of the appendix was not correlated with imaging or surgical findings.Some appendiceal signs were written in a non-English language and may not have been appropriately translated(e.g.,Blumberg-Shchetkin and Rovsing).In other cases,the sign described differs from the original report(e.g.,Rovsing,Blumberg-Shchetkin,and Cope sign,Murphy syndrome).Because of these studies limitations,gaps remain regarding the signs’utility in the bedside diagnosis of acute appendicitis.Based on the few studies available with these limitations in mind,the results suggest that a positive test is more likely to be found in acute appendicitis.However,a negative test does not exclude the diagnosis.Hence,these tests increase the likelihood of ruling in acute appendicitis when positive but are less helpful in ruling out disease when negative.Knowledge about the correct method of performing the sign may be a valuable adjunct to the surgeon in further increasing their pretest probability of disease.Furthermore,it may allow surgeons to study these signs further to better understand their role in clinical practice.In the interim,these signs should continue to be used as a tool to supplement the clinical diagnosis.
文摘The aim of this study was to evaluate the incidence and severity of erectile dysfunction (ED) and hypogonadism in 193 men presenting with lower urinary tract symptoms (LUTSs) in the younger (20 - 39 years old) and older (40 - 60 years old) age groups depending on the presence of metabolic syndrome (MetS). Triglycerides, glucose and high-density lipoprotein cholesterol, serum total testosterone (TT), sex hormone-binding globulin, prostate-specific antigen, pituitary hormones levels were measured in serum. Standardized criteria (2009) were used to determine the prevalence of MetS. Patients were assessed based on the International Prostate Symptom Score (IPSS) and the IPSS-Quality of Life (IPSS-QoL) for LUTSs and the International Index of Erectile Function (IIEF) for ED. Hypogonadism was determined in accordance with the ISA, ISSAM, EAU, EAA and ASA recommendations. In men with MetS in the younger age group the incidence of ED was 2.4 times higher, and that of low TT level and hypogonadism was 8.4 times higher compared to men without the syndrome. In the older age group, an increased incidence of ED and low TT level in men with MetS compared to men without the syndrome was on the trend level, but the incidence of hypogonadism was for sure higher (by 1.6 times). In conclusion, the study showed that ED and hypogonadism are associated with MetS by a high degree of certainty in young men with LUTSs. In men of the older age group with LUTSs, the presence of MetS is not so clearly associated with ED and hypogonadism due to the fact that the incidence of these urogenital diseases is also high in men without MetS.
文摘The signing ceremony of strategic cooperation agreement between China Chamber of International Commerce(CCOIC)and Suning Commerce Group Co.,Ltd(Suning)was heldin Beijing on August 23.Chairman of the CCPIT and CCOIC Jiang Zengwei and chairman of Suning Zhang Jindong attended and witnessed the ceremony.Secretary-General of the CCOIC Yu Jianlong and vice president of
基金supported by Duy Tan University,Da Nang,Vietnam.
文摘The representative collective digital signature,which was suggested by us,is built based on combining the advantages of group digital signature and collective digital signature.This collective digital signature schema helps to create a unique digital signature that deputizes a collective of people representing different groups of signers and may also include personal signers.The advantage of the proposed collective signature is that it can be built based on most of the well-known difficult problems such as the factor analysis,the discrete logarithm and finding modulo roots of large prime numbers and the current digital signature standards of the United States and Russian Federation.In this paper,we use the discrete logarithmic problem on prime finite fields,which has been implemented in the GOST R34.10-1994 digital signature standard,to build the proposed collective signature protocols.These protocols help to create collective signatures:Guaranteed internal integrity and fixed size,independent of the number of members involved in forming the signature.The signature built in this study,consisting of 3 components(U,R,S),stores the information of all relevant signers in the U components,thus tracking the signer and against the“disclaim of liability”of the signer later is possible.The idea of hiding the signer’s public key is also applied in the proposed protocols.This makes it easy for the signing group representative to specify which members are authorized to participate in the signature creation process.
基金This research was supported by the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT and Future Planning(NRF-2019R1A2C1084308).
文摘American Sign Language(ASL)images can be used as a communication tool by determining numbers and letters using the shape of the fingers.Particularly,ASL can have an key role in communication for hearing-impaired persons and conveying information to other persons,because sign language is their only channel of expression.Representative ASL recognition methods primarily adopt images,sensors,and pose-based recognition techniques,and employ various gestures together with hand-shapes.This study briefly reviews these attempts at ASL recognition and provides an improved ASL classification model that attempts to develop a deep learning method with meta-layers.In the proposed model,the collected ASL images were clustered based on similarities in shape,and clustered group classification was first performed,followed by reclassification within the group.The experiments were conducted with various groups using different learning layers to improve the accuracy of individual image recognition.After selecting the optimized group,we proposed a meta-layered learning model with the highest recognition rate using a deep learning method of image processing.The proposed model exhibited an improved performance compared with the general classification model.
文摘针对航空母舰飞行甲板上舰载机弹药保障面临的调度效率不高的问题,提出了一种改进灰狼优化(grey wolf optimizer, GWO)算法。根据甲板上多升降机多运输车的场景特点,建立了由多车场出发、向多目标转运的问题模型。融合遗传算法算子交叉思想实现了对灰狼种群初始解的初步优化,并通过直线转运路径中间点定义、整数编码、负整数标志分组等方法实现了对GWO算法求解过程的改进。同时,增加了灰狼个体自由狩猎流程,有效克服了结果陷入局部最优和早熟的问题。最终,通过对场景实例的优化求解,验证了所提方法的有效性和可行性。
