Research on strategic risk identification method of equipment system development based on system dynamics

Strategic management of equipment system develop-ment must attach importance to effective strategic risk manage-ment.Aiming at the identification of strategic risk of equipment system development,firstly,the source of strategic risk of equip-ment system development is analyzed and classified.Based on this,a causal loop diagram of strategic risk of equipment sys-tem development based on system dynamics is established.The system dynamics analysis software Vensim PLE is used to carry out the risk influencing factors analysis,risk consequences ana-lysis,risk feedback loop identification and corresponding pre-control measures,and achieves a good risk identification effect.

Construction and Implementation of OBE-based Practical Course for Software System Development with Solid Foundation and Continuous Improvement

Software engineering is a highly practical major,and students need a lot of hands-on practice to transform the theoretical contents learned in class into the practical ability to solve practical problems,so practical courses are an essential and important part in the process of training talents in software engineering.From the point of view of cultivating talents in software engineering,this paper expounds the important position of practical courses in software engineering in the process of cultivating talents,analyzes the problems in the existing practical courses,and puts forward the construction ideas and characteristics of practical courses in software engineering which strengthen the foundation,advance steadily,and face the output.Taking the practical course for software system development as an example,this paper introduces in detail the concrete implementation process,achievements,existing problems and countermeasures of the course.

Development and Application of the Edition System of Agricultural Meteorology Short Message in Liaoning Province

In order to meet the needs of Agricultural Meteorology business and research,an edition system of agricultural meteorology short message was established based on the Microsoft Access 2000 database and visualization developing software Visual Basic 6.0 in Liaoning Province.The basic principles of agro-meteorological text editing and system optimization ideas were pointed out.The meteorological conditions of the main crops growth needed in material library were introduced.

Global Memory Net and the development of digital image information management system: Experience and practice

Global Memory Net (GMNet) is intended to be an effective gateway to the world cultural, historical, and heritage image collections from selected academic educational and research partners in the world. Much of these unique collections of great value to education and research are not currently accessible due to distance, form, and technical barriers. This project is to find new ways to enable users to access and exploit these significant research collections via global network. As GMNet is ending its first 5-year phase in October 2005, it has contributed substantially to the community building in digital library development by ac- commodating numerous collaborators and technical staff from various parts of the world to spend 3 to 5 months as a full-member of the GMNet team in Boston. They have come from different parts of China—such as Sichuan, Hainan, Shanghai and Xi’an; Croatia; and Hanoi, Vietnam. In addition to contribute to the overall system development and enhancement of system function- alities, they have brought valuable sample image collections of their own institutions/countries, and actually developed prototype collections as a part of GMNet. This paper describes the exciting and productive experience of the first of this visiting research group in developing the GMNet’s Version 2.0 PHP-based system under Prof. Chen’s overall supervision. It also describes both the system’s technical level structure—user/Web-based application/data, and complex functionalities with multi-collection, multi-lingual, multi-modal searching capabilities; system management capabilities; as well as provisions for user uploads and retrieval for our own projects. This Version 2.0 system is built on the Linux/Apache/PHP/MySQL platform. What is described in this paper is an actual case which has formed a base for further new development by others in the research group. It demonstrates fully the value of the synergistic collaboration among global partners for universal digital library development. More information can be found in http://www.memorynet.org/.

Development and application of a GIS-based artificial neural network system for water quality prediction: a case study at the Lake Champlain area

Artificial Neural Network(ANN)models have been extensively applied in the prediction of water resource variables,and Geographical Information System(GIS)includes powerful functions to visualize spatial data.In order to provide an efficient tool for environmental assessment and management that combines the advantages of these two modules,a GIS-based ANN water quality prediction system was developed in the present study.The ANN module and ArcGIS Engine module,along with a dynamic database,were imbedded in the system,which integrates water quality prediction via the ANN model and spatial presentation of the model results.The structure of the ANN model could be modified through the graphical user interface to optimize the model performance.The developed system was applied to a real case study for the prediction of the total phosphorus concentration in the Lake Champlain area.The prediction results were verified with the monitoring data,and the performance of the developed model was further evaluated through graphical techniques and quantitative statistical methods.Overall,the developed system provided satisfactory prediction results,and spatial distribution maps of the predicted results were obtained,which coincided with the monitored values.The developed GIS-based ANN water quality prediction system could serve as an efficient tool for engineers and decision makers.

Research development of digital maintenance and management system for long-span cable-stayed bridges

Digital cable-stayed bridge maintenance and management system （DCBMS） was developed for the need of maintenance and management of long-span cable-stayed bridges. In this paper, the major functions and theoretical application of eight modules were systematically stated with the background of Harbin Songhua River cable-stayed bridge, which include data management module, inspection and measurement module, assessment module, finite dement analysis module, disease diagnosis and prediction module, maintenance module, query module and help module. By analyzing and calculating the data from manual inspection database, basic database and health monitoring subsystem, DCBMS can accomplish the functions like life prediction, disease diagnosis, comprehensive assessment, maintenance and management of bridges. Therefore, the maintenance and management of long-span cable-stayed bridges can be made digital, professional and scientific. By running this system, a real-time and specific technical guidance can be provided for the maintainers and managers of long- span cable-stayed bridges.

Analyzing the role of extracellular matrix during nervous system development to advance new regenerative strategies

Regeneration in the central nervous system （CNS） is limited, and CNS damage often leads to cognitive impairment or permanent functional motor and sensory loss. Impaired regenerative capacity is multifactorial and includes inflammation, loss of the blood-brain barrier, and alteration in the extracellular matrix （ECM）. One of the main problems is the formation of a glial scar and the production of inhibitory ECM, such as proteoglycans, that generates a physical and mechanical barrier, impeding axonal regrowth （Figure 1A）.

New Stage of the Northwest China 330 kV Power System Development - A Brief Introduction of System Planning in Northwest China to the Year 2000

The system planning of the Northwest China 330 kV Power System from present to the year 2000 is introduced in this paper. Some technical problems arising from the system planning, such as network configuration, system stability and reactive power compensation etc. are also briefly summarized.

Developmental systems biology flourishing on new technologies

Organism development is a systems level process. It has benefited greatly from the recent technological advances in the field of systems biology. DNA microarray, phenome, interactome and transcriptome mapping, the new generation of deep sequencing technologies, and faster and better computational and modeling approaches have opened new frontiers for both systems biologists and developmental biologists to reexamine the old developmental biology questions, such as pattern formation, and to tackle new problems, such as stem cell reprogramming. As showcased in the International Developmental Systems Biology Symposium organized by Chinese Academy of Sciences, developmental systems biology is flourishing in many perspectives, from the evolution of developmental systems, to the underlying genetic and molecular pathways and networks, to the genomic, epigenomic and noncoding levels, to the computational analysis and modeling. We believe that the field will continue to reap rewards into the future with these new approaches.

Research and Development on NC System of Gear-hobbing Machine based on Zero-programming Technology

By the analysis of roller gear processing technology, combining with gear meshing mechanism and motion relationship, models for rolling gear machining parameter and zero-programming are established. In this paper, the automatic generation technology of NC program for CNC gear machining process has been studied and the zero-programming system architecture of open CNC gear-hobbing machine has been presented. In the design and development of the system, human computer interaction, programming algorithm and the design of each function module have bean done. Application test shows that the expected design requirements have been achieved.

Distributed Generation Influence on Power Distribution System Development in Poland

A lot of individual electricity sources of small power common （called distributed generation） occurred in Polish power sector during the last period. Gradual increases of distributed generation will cover current and future demand of consumers as well as allow to keep essential reserves in distribution and transmission grids. Emphasizing on this problem can upgrade economic efficiency and grid significance of distributed generation for investors and distribution utilities in Poland.

Neural Correlates of Developmental Coordination Disorder: The Mirror Neuron System Hypothesis

Primary impairments of developmental coordination disorder (DCD) include impairments in motor skill, motor learning, and imitation. Such difficulties present challenges for individuals with DCD and may persist into adulthood, negatively impacting daily life in school, work, and social domains. A better understanding of the neural correlates of motor and imitation impairments in DCD holds the potential for informing development of treatment approaches to address these impairments. Although the disorder is assumed to be of neurological origin, little is known of the brain-based etiology of DCD. In recent years the discovery of a fronto-parietal circuit—known as the mirror neuron system—has enabled researchers to better understand imitation, general motor functions, and aspects of social cognition. Given its involvement in imitation and other motor functions, we propose that dysfunction in the mirror neuron system may underlie the characteristic impairments of DCD. We review literature pertaining to the mirror neuron system and develop a theory of disordered mirror neuron functioning in DCD. Finally, we review the limited neuroimaging literature available on neural correlates of DCD and show that the findings from those investigations are congruent with a mirror neuron system theory of DCD. Future research in this population should be designed to investigate specifically mirror neuron regions in individuals with DCD during skilled motor tasks and imitation in particular.

国内教师评价研究可视化分析:现状与启示

基于CSSCI来源期刊论文为研究对象,对近二十年来国内教师评价研究进行可视化分析,结果显示:近二十年来国内教师评价研究发文量整体增长速度放缓;作者之间和研究机构之间均缺乏合作;研究热点聚焦于评价制度、评价政策、发展性教师评价、教师评价素养等;研究经历了基础、强化、深化三个发展阶段。在反思国内教师评价研究进展的基础上,从强化实证研究、推进校本化特色研究、加强合作研究三个方面提出了未来研究应着力的方向,以期进一步推动国内教师评价研究的理论深化。

职业教育发展性资助育人体系构建

在职业教育发展的过程中,开展资助工作不仅有助于保障学生完成学业,而且还能进一步促使高职院校落实立德树人根本任务,使学生成为社会需要的人才,以便在毕业后顺利实现就业。积极构建发展性资助育人体系,应认识到现阶段仍面临管理、效能释放等问题,需要政府、院校和企业协力开展工作,为学生打造资助育人发展性平台,在科技支撑下动态反馈育人成效,确保建立科学育人体系,推动职业教育资助工作可持续开展。

叙事治疗视角下双核系统概念的构建

双核系统是叙事治疗在中国运用发展中一个创新概念,即来访者同时拥有原始模式与发展模式的内在状态。本文构建了双核系统的概念,双核系统重新定位了问题与资源的关系,强调重视问题经验,协助咨询师定位来访者的“最近发展区”。它使来访者的问题与疗愈既对立又统一,形成动态的、二元的自我认同体系,最终为来访者生命赋能。

薄荷醇对果蝇产卵驱避作用及毒杀效果

【目的】研究薄荷醇对常见几种果蝇Drosophila产卵的驱避作用,并通过后代存活率和发育历期及成虫死亡率以评价薄荷醇毒杀作用。【方法】应用产卵双向选择装置,在0.05%,0.1%和0.2%薄荷醇作用下检测果蝇的产卵选择性;利用双染料食物偏好实验检测薄荷醇对果蝇的摄食行为影响;利用产卵装置,检测薄荷醇对黑腹果蝇D.melanogaster的位置的影响;利用黑暗条件、摘除触角和前腿以及Orco 2突变体测定薄荷醇对黑腹果蝇产卵选择性的影响;并测定薄荷醇对黑腹果蝇后代存活率与发育历期的影响;测定薄荷醇对黑腹果蝇成虫寿命、奔跑速度和攀爬速度的影响;利用二氢乙锭(dihydroethidium,DHE)荧光染色技术,评估喂食1%薄荷醇3 d后黑腹果蝇成虫肠道内活性氧(reactive oxygen species,ROS)水平。【结果】薄荷醇对果蝇雌成虫产卵有驱避性,在0.05%,0.1%和0.2%薄荷醇作用下黑腹果蝇雌成虫的产卵指数分别为-0.42,-0.58和-0.98;铃木氏果蝇D.suzukii、雅库巴果蝇D.yakuba和拟暗果蝇D.pseudoobscura雌成虫对薄荷醇的产卵避性反应与黑腹果蝇雌成虫相同。在摄食过程中,黑腹果蝇及铃木氏果蝇成虫均对薄荷醇培养基产生明显排斥反应。薄荷醇培养基对黑腹果蝇成虫有明显的位置驱避性,0.05%,0.1%和0.2%薄荷醇处理下位置指数分别为-0.32,-0.44和-0.84。各个浓度的薄荷醇对黑暗环境和摘除前足的黑腹果蝇雌成虫仍然表现出显著的产卵驱避性,但在摘除黑腹果蝇成虫触角的条件下,薄荷醇对它们的产卵驱避性显著降低,0.05%,0.1%和0.2%薄荷醇作用下产卵指数分别为-0.04,-0.06和-0.26,薄荷醇对Orco 2突变体仍旧有产卵驱避性。与对照组相比,1%薄荷醇处理组黑腹果蝇成蛹和成虫羽化时间明显延长,分别延长了0.74和0.73 d,存活率明显下降,分别下降了63.2%和91.3%。随着薄荷醇浓度的增加黑腹果蝇成虫存活率呈现下降的趋势,且明显降低其奔跑和攀爬速度,即薄荷醇降低了亲代黑腹果蝇的适合度。1%薄荷醇处理3 d显著提升了黑腹果蝇成虫肠道内的ROS水平。【结论】薄荷醇通过嗅觉介导了果蝇的产卵避性反应,且薄荷醇降低了后代和亲代的适合度和存活率。

环境变革:高等教育系统应对发展的逻辑阐释

应对环境变革既是高等教育系统不容回避的客观事项,也是高等教育“系统外部协同适应发展”与“系统内部自组织优化”的有机统一。其在外部逻辑上蕴含着“预判—作为、刺激—反应、危机—应对”三种基本样态,意在“主动求变以保持系统的稳态运行、积极应变以重塑系统的发展生态、因势而变以促进系统的发展转化”。在内部逻辑上通过系统的“输入—生产—输出”联结,需要高等教育系统于理想功能发挥和现实可支配资源间做出选择调和,进而达至高等教育系统整体功能和效益的最大化。为更好应对急剧的外部环境变革,高等教育系统可从外部考量“认清高等教育战略定力内涵并坚定保持战略定力”,从内部考量“因势利导应对多元环境变革并危中寻机谋划发展”。

含吡啶类腈类医药中间体废盐对海洋青鳉鱼胚胎的毒性效应

工业废盐是化工生产过程中产生的副产结晶盐。农药、医药等精细化工行业的生产中往往伴随着大量废盐的产生,《国家危险废物名录》中明确将多种化学制药、农药生产过程中产生的废盐列为危险废物。然而,由于处理成本高昂和处置能力不足,废盐限制了企业的健康发展。在《危险废物环境管理指南化工废盐》中明确了工业废盐无害化排海的相关要求,但目前仍缺少相关领域的实验研究。海洋青鳉鱼(Oryzias melastigma)具有与斑马鱼类似的研究特征优势,是国际生命科学学会(ILSI)与健康和环境科学研究所(HESI)认定的海洋生态毒理学的重要研究工具。研究了含吡啶类腈类医药中间体废盐和经过实验室处理后的除杂盐对海洋青鳉鱼胚胎的急性毒性、发育毒性以及对抗氧化系统、免疫系统的影响。结果表明,废盐暴露对海洋青鳉鱼胚胎的生存和发育有显著影响并造成系统性损伤,而除杂盐对海洋青鳉鱼胚胎没有较大影响。本研究为废盐排海提供了基础的理论支持,也为后续实验开展提供了良好的思路引导。

Neurotrophic factors: from neurodevelopmental regulators to novel therapies for Parkinson's disease

Neuroprotection and neuroregeneration are two of the most promising disease-modifying ther- apies for the incurable and widespread Parkinson＇s disease. In Parkinson＇s disease, progressive degeneration of nigrostriatal dopaminergic neurons causes debilitating motor symptoms. Neurotrophic factors play important regulatory roles in the development, survival and maintenance of specific neuronal populations. These factors have the potential to slow down, halt or reverse the loss of nigrostriatal dopaminergic neurons in Parkinsoffs disease. Several neurotrophic fac- tors have been investigated in this regard. This review article discusses the neurodevelopmental roles and therapeutic potential of three dopaminergic neurotrophic factors： glial cell line-derived neurotrophic factor, neurturin and growth/differentiation factor 5.