The tendril is a climbing organ in cucurbits and functions in physical support and to avoid shading by neighboring vegetation.However,how cucurbits produce tendrils to obtain climbing ability is largely unknown.In thi...The tendril is a climbing organ in cucurbits and functions in physical support and to avoid shading by neighboring vegetation.However,how cucurbits produce tendrils to obtain climbing ability is largely unknown.In this study,tendril phenotypes were investigated during different developmental stages.Our results revealed that tendril growth exhibited an age-dependent pattern in cucurbits.Tendril growth was inhibited,and the tendril was formed as a short tendril[nonfunctional tendril(nonF-tendril),approximately 0.1 cm]during the seedling stage.In contrast,enhanced cell proliferation and cell expansion led to rapid elongation of the tendril during the climbing stage,and the tendril formed as a functional tendril(F-tendril,approximately 30 cm)to obtain climbing ability.RT-qPCR detection showed that age-dependent tendril growth correlated negatively with the abundance of the conserved age regulator CsmiR156.Defoliation induced CsmiR156 to inhibit CsSPLs,and F-tendril formation and climbing ability were delayed in defoliated cucumbers,which confirmed the role of CsmiR156 in regulating tendril growth in vivo.Additionally,exogenous gibberellin(GA)treatment showed that GA positively regulated tendril growth,and RT-qPCR detection showed that the GA bio-synthetic genes and metabolic genes were affected by age pathway,suggesting that the age pathway depended on GA bio-synthetic and metabolic pathway to regulate cell expansion to determine tendril growth.In summary,our work reveals that change in tendril type is an important marker of phase transition in cucumber,and tendril growth is regulated by an intrinsic developmental age signal,ensuring that the cucumber obtains climbing ability at a suitable age.展开更多
Urbanization research is essential for the sustainable use of regional land resources and ecological environment protection.The expansion process and driving factors of urban construction land at different scales in t...Urbanization research is essential for the sustainable use of regional land resources and ecological environment protection.The expansion process and driving factors of urban construction land at different scales in the middle reaches of the Yellow River(MRYR)have not been comprehensively elucidated.In this study,we explored the distribution pattern of urban construction land on different slope gradients at different scales and analyzed its influencing factors.The main findings were as follows:(1)There has been significant expansion of urban construction land in the MRYR over the past 20 years.Spatial heterogeneity was observed in the regional urban construction land expansion process among different geomorphic regions.(2)The urban construction land in the MRYR was expanded vertically to areas with slopes of>5°,particularly in 2005–2010.Significant slope climbing of urban construction land was observed in the loess hilly-gully and rocky mountain areas.(3)In MRYR,68.45%of the counties were categorized as the slope-climbing types,including 37.38%high-slope-climbing types.(4)The regional population density and economic development level were closely associated with regional urban construction land area variability.(5)The climbing process of regional urban construction can effectively alleviate farmland encroachment and pressure on the regional ecological environment.The urban expansion of the metropolitan distribution areas in the Plain region(such as Xi'an,Taiyuan)had a relatively significant impact on the local carbon storage.展开更多
Background:Cross-sectional evidence and small-scale trials suggest positive effects of stair climbing on cardiometabolic disease and glucose regulation.However,few studies have examined the long-term association betwe...Background:Cross-sectional evidence and small-scale trials suggest positive effects of stair climbing on cardiometabolic disease and glucose regulation.However,few studies have examined the long-term association between stair climbing and the incidence of type 2 diabetes(T2D).We aimed to prospectively evaluate the association of stair climbing with T2D and assess modifications by genetic predisposition to T2D.Methods:We included 451,699 adults(mean age=56.3±8.1 years,mean±SD;55.2%females)without T2D at baseline in the UK Biobank and followed up to March 31,2021.Stair climbing information was collected through the touchscreen questionnaire.Genetic risk score for T2D consisted of 424 single nucleotide polymorphisms.Results:During a median follow up of 12.1 years,14,896 T2D cases were documented.Compared with participants who reported no stair climbing,those who climbed stairs regularly had a lower risk of incident T2D(10-50 steps/day:hazard ratio(HR)=0.95,95%confidence interval(95%CI):0.89-1.00;60-100 steps/day:HR=0.92,95%CI:0.87-0.98;110-150 steps/day:HR=0.86,95%CI:0.80-0.91;>150 steps/day:HR=0.93,95%CI:0.87-0.99,p for trend=0.0007).We observed a significant interaction between stair climbing and genetic risk score on the subsequent T2D risk(p for interaction=0.0004),where the risk of T2D showed a downward trend in subjects with low genetic risk and those who reported stair climbing activity of 110-150 steps/day appeared to have the lowest overall T2D risk among those with intermediate to high genetic risk.Conclusion:A higher number of stairs climbed at home was associated with lower T2D incidence risk,especially among individuals with a low genetic predisposition to T2D.These findings highlight that stair climbing,as incidental physical activity,offers a simple and low-cost complement to public health interventions for T2D prevention.展开更多
In this paper,a new tracked wall climbing robot with permanent magnetic units is designed,and the tension degree of robot’s tracks is found to have a significant impact on the robot’s adsorption performance.This tra...In this paper,a new tracked wall climbing robot with permanent magnetic units is designed,and the tension degree of robot’s tracks is found to have a significant impact on the robot’s adsorption performance.This tracked wall climbing robot is a remotely controlled robot.All the control devices can be installed on the robot body.All the permanent magnetic units are arranged on the light track.In order to illustrate the relationship between the tension degree and the adsorption performance,when absorbed on the vertical surface and 180⁃degree inverted surface,the static force analysis of the robot is presented.Finally,experiments were demonstrated to prove that higher tension degree of tracks can make adsorption performance better.展开更多
Wireless Sensor Networks are composed of autonomous sensing devices which are interconnected to form a closed network.This closed network is intended to share sensitive location-centric information from a source node ...Wireless Sensor Networks are composed of autonomous sensing devices which are interconnected to form a closed network.This closed network is intended to share sensitive location-centric information from a source node to the base station through efficient routing mechanisms.The efficiency of the sensor node is energy bounded,acts as a concentrated area for most researchers to offer a solution for the early draining power of sensors.Network management plays a significant role in wireless sensor networks,which was obsessed with the factors like the reliability of the network,resource management,energy-efficient routing,and scalability of services.The topology of the wireless sensor networks acts dri-ven factor for network efficiency which can be effectively maintained by perform-ing the clustering process effectively.More solutions and clustering algorithms have been offered by various researchers,but the concern of reduced efficiency in the routing process and network management still exists.This research paper offers a hybrid algorithm composed of a memetic algorithm which is an enhanced version of a genetic algorithm integrated with the adaptive hill-climbing algorithm for performing energy-efficient clustering process in the wireless sensor networks.The memetic algorithm employs a local searching methodology to mitigate the premature convergence,while the adaptive hill-climbing algorithm is a local search algorithm that persistently migrates towards the increased elevation to determine the peak of the mountain(i.e.,)best cluster head in the wireless sensor networks.The proposed hybrid algorithm is compared with the state of art clus-tering algorithm to prove that the proposed algorithm outperforms in terms of a network life-time,energy consumption,throughput,etc.展开更多
基金supported by the Natural Science Foundation of Zhejiang province(Grant Nos.LZ20C150001,LY21C150002)National Natural Science Foundation of China(Grant No.32202583).
文摘The tendril is a climbing organ in cucurbits and functions in physical support and to avoid shading by neighboring vegetation.However,how cucurbits produce tendrils to obtain climbing ability is largely unknown.In this study,tendril phenotypes were investigated during different developmental stages.Our results revealed that tendril growth exhibited an age-dependent pattern in cucurbits.Tendril growth was inhibited,and the tendril was formed as a short tendril[nonfunctional tendril(nonF-tendril),approximately 0.1 cm]during the seedling stage.In contrast,enhanced cell proliferation and cell expansion led to rapid elongation of the tendril during the climbing stage,and the tendril formed as a functional tendril(F-tendril,approximately 30 cm)to obtain climbing ability.RT-qPCR detection showed that age-dependent tendril growth correlated negatively with the abundance of the conserved age regulator CsmiR156.Defoliation induced CsmiR156 to inhibit CsSPLs,and F-tendril formation and climbing ability were delayed in defoliated cucumbers,which confirmed the role of CsmiR156 in regulating tendril growth in vivo.Additionally,exogenous gibberellin(GA)treatment showed that GA positively regulated tendril growth,and RT-qPCR detection showed that the GA bio-synthetic genes and metabolic genes were affected by age pathway,suggesting that the age pathway depended on GA bio-synthetic and metabolic pathway to regulate cell expansion to determine tendril growth.In summary,our work reveals that change in tendril type is an important marker of phase transition in cucumber,and tendril growth is regulated by an intrinsic developmental age signal,ensuring that the cucumber obtains climbing ability at a suitable age.
基金supported by Fundamental Research Program of Shanxi Province[Grant No.202303021221154]the Project of Shanxi Province Graduate Education and Teaching Reform[2022YJJG48]。
文摘Urbanization research is essential for the sustainable use of regional land resources and ecological environment protection.The expansion process and driving factors of urban construction land at different scales in the middle reaches of the Yellow River(MRYR)have not been comprehensively elucidated.In this study,we explored the distribution pattern of urban construction land on different slope gradients at different scales and analyzed its influencing factors.The main findings were as follows:(1)There has been significant expansion of urban construction land in the MRYR over the past 20 years.Spatial heterogeneity was observed in the regional urban construction land expansion process among different geomorphic regions.(2)The urban construction land in the MRYR was expanded vertically to areas with slopes of>5°,particularly in 2005–2010.Significant slope climbing of urban construction land was observed in the loess hilly-gully and rocky mountain areas.(3)In MRYR,68.45%of the counties were categorized as the slope-climbing types,including 37.38%high-slope-climbing types.(4)The regional population density and economic development level were closely associated with regional urban construction land area variability.(5)The climbing process of regional urban construction can effectively alleviate farmland encroachment and pressure on the regional ecological environment.The urban expansion of the metropolitan distribution areas in the Plain region(such as Xi'an,Taiyuan)had a relatively significant impact on the local carbon storage.
基金supported by the National Key Research and Development Program of China(grant number 2020YFC2006300)the Young Scientists Fund of the National Natural Science Foundation of China(grant number 82103835)。
文摘Background:Cross-sectional evidence and small-scale trials suggest positive effects of stair climbing on cardiometabolic disease and glucose regulation.However,few studies have examined the long-term association between stair climbing and the incidence of type 2 diabetes(T2D).We aimed to prospectively evaluate the association of stair climbing with T2D and assess modifications by genetic predisposition to T2D.Methods:We included 451,699 adults(mean age=56.3±8.1 years,mean±SD;55.2%females)without T2D at baseline in the UK Biobank and followed up to March 31,2021.Stair climbing information was collected through the touchscreen questionnaire.Genetic risk score for T2D consisted of 424 single nucleotide polymorphisms.Results:During a median follow up of 12.1 years,14,896 T2D cases were documented.Compared with participants who reported no stair climbing,those who climbed stairs regularly had a lower risk of incident T2D(10-50 steps/day:hazard ratio(HR)=0.95,95%confidence interval(95%CI):0.89-1.00;60-100 steps/day:HR=0.92,95%CI:0.87-0.98;110-150 steps/day:HR=0.86,95%CI:0.80-0.91;>150 steps/day:HR=0.93,95%CI:0.87-0.99,p for trend=0.0007).We observed a significant interaction between stair climbing and genetic risk score on the subsequent T2D risk(p for interaction=0.0004),where the risk of T2D showed a downward trend in subjects with low genetic risk and those who reported stair climbing activity of 110-150 steps/day appeared to have the lowest overall T2D risk among those with intermediate to high genetic risk.Conclusion:A higher number of stairs climbed at home was associated with lower T2D incidence risk,especially among individuals with a low genetic predisposition to T2D.These findings highlight that stair climbing,as incidental physical activity,offers a simple and low-cost complement to public health interventions for T2D prevention.
基金the Beijing Natural Science Foundation(Grant No.3194047)the Joint Program of Beijing Municipal Foundation and Education Commission(Grant No.KZ202010009015)the National Natural Science Foundation of China(Grant No.51775002).
文摘In this paper,a new tracked wall climbing robot with permanent magnetic units is designed,and the tension degree of robot’s tracks is found to have a significant impact on the robot’s adsorption performance.This tracked wall climbing robot is a remotely controlled robot.All the control devices can be installed on the robot body.All the permanent magnetic units are arranged on the light track.In order to illustrate the relationship between the tension degree and the adsorption performance,when absorbed on the vertical surface and 180⁃degree inverted surface,the static force analysis of the robot is presented.Finally,experiments were demonstrated to prove that higher tension degree of tracks can make adsorption performance better.
文摘Wireless Sensor Networks are composed of autonomous sensing devices which are interconnected to form a closed network.This closed network is intended to share sensitive location-centric information from a source node to the base station through efficient routing mechanisms.The efficiency of the sensor node is energy bounded,acts as a concentrated area for most researchers to offer a solution for the early draining power of sensors.Network management plays a significant role in wireless sensor networks,which was obsessed with the factors like the reliability of the network,resource management,energy-efficient routing,and scalability of services.The topology of the wireless sensor networks acts dri-ven factor for network efficiency which can be effectively maintained by perform-ing the clustering process effectively.More solutions and clustering algorithms have been offered by various researchers,but the concern of reduced efficiency in the routing process and network management still exists.This research paper offers a hybrid algorithm composed of a memetic algorithm which is an enhanced version of a genetic algorithm integrated with the adaptive hill-climbing algorithm for performing energy-efficient clustering process in the wireless sensor networks.The memetic algorithm employs a local searching methodology to mitigate the premature convergence,while the adaptive hill-climbing algorithm is a local search algorithm that persistently migrates towards the increased elevation to determine the peak of the mountain(i.e.,)best cluster head in the wireless sensor networks.The proposed hybrid algorithm is compared with the state of art clus-tering algorithm to prove that the proposed algorithm outperforms in terms of a network life-time,energy consumption,throughput,etc.