Two new tetracyclic taxane diterpenoids----yunnanxol(1) and yunnanxamine(2)have been isolated from the bark of Taxus yunnanensis Cheng et L.K.Fu.Their structures have been established from the spectral data,mainly fro...Two new tetracyclic taxane diterpenoids----yunnanxol(1) and yunnanxamine(2)have been isolated from the bark of Taxus yunnanensis Cheng et L.K.Fu.Their structures have been established from the spectral data,mainly from MS,highfield ~1H NMR,~1H-~1H COSY, ^(13)C NMR,^(13)C-~1H COSY and ^(13)C-~1H COLOC spectroscopies.展开更多
The aim of current study was to investigate the chemical constituents of the needles of Taxus media. The isolation and purification of components were achieved by a series of chromatography including silica gel, Sepha...The aim of current study was to investigate the chemical constituents of the needles of Taxus media. The isolation and purification of components were achieved by a series of chromatography including silica gel, Sephadex LH-20, MCI and reversed- phase HPLC. Their structures were indentified based on 1D, 2D NMR, and mass spectral analysis. Seven taxane diterpenoids were isolated and identified as ll3,2tt,9ct,1013-tetrahydroxy-5ct-cinnamoyloxy-3,11-cyclotaxa-4（20）-en-13-one （1）, 2it, 7[3, 9ct, 1013, 13tt-pentaacetoxytaxa-4（20）, 11-dien-Sct-ol （2）, 2-deacetoxy-5-decinnamoyltaxinine J （3）, taxuspine F （4）, taxuspinanane K （5）, taxchin A （6）, and baccatin IV （7）. Among them, 1 is a new compound and compounds 2, 5, 6 and 7 are isolated from Taxus media for the first time.展开更多
Two new baccatin Ⅲ type taxoids, 13-Cinnamoylbaccatin Ⅲ (1) and 7-xylosylbaccatin Ⅲ(2), have been isolated from the barks of Taxus yunnanensis. The structures were elucidated by spectral means.
文摘Two new tetracyclic taxane diterpenoids----yunnanxol(1) and yunnanxamine(2)have been isolated from the bark of Taxus yunnanensis Cheng et L.K.Fu.Their structures have been established from the spectral data,mainly from MS,highfield ~1H NMR,~1H-~1H COSY, ^(13)C NMR,^(13)C-~1H COSY and ^(13)C-~1H COLOC spectroscopies.
基金National Natural Science Foundation of China(Grant No.30973628)
文摘The aim of current study was to investigate the chemical constituents of the needles of Taxus media. The isolation and purification of components were achieved by a series of chromatography including silica gel, Sephadex LH-20, MCI and reversed- phase HPLC. Their structures were indentified based on 1D, 2D NMR, and mass spectral analysis. Seven taxane diterpenoids were isolated and identified as ll3,2tt,9ct,1013-tetrahydroxy-5ct-cinnamoyloxy-3,11-cyclotaxa-4（20）-en-13-one （1）, 2it, 7[3, 9ct, 1013, 13tt-pentaacetoxytaxa-4（20）, 11-dien-Sct-ol （2）, 2-deacetoxy-5-decinnamoyltaxinine J （3）, taxuspine F （4）, taxuspinanane K （5）, taxchin A （6）, and baccatin IV （7）. Among them, 1 is a new compound and compounds 2, 5, 6 and 7 are isolated from Taxus media for the first time.
文摘Two new baccatin Ⅲ type taxoids, 13-Cinnamoylbaccatin Ⅲ (1) and 7-xylosylbaccatin Ⅲ(2), have been isolated from the barks of Taxus yunnanensis. The structures were elucidated by spectral means.
