A new approach for flexoelectricmaterial shape optimization is proposed in this study.In this work,a proxymodel based on artificial neural network(ANN)is used to solve the parameter optimization and shape optimization...A new approach for flexoelectricmaterial shape optimization is proposed in this study.In this work,a proxymodel based on artificial neural network(ANN)is used to solve the parameter optimization and shape optimization problems.To improve the fitting ability of the neural network,we use the idea of pre-training to determine the structure of the neural network and combine different optimizers for training.The isogeometric analysis-finite element method(IGA-FEM)is used to discretize the flexural theoretical formulas and obtain samples,which helps ANN to build a proxy model from the model shape to the target value.The effectiveness of the proposed method is verified through two numerical examples of parameter optimization and one numerical example of shape optimization.展开更多
In college badminton teaching,teachers utilize the group cooperative learning method,which not only helps to improve students’badminton skill level but also cultivates their teamwork spirit,communication skills,and s...In college badminton teaching,teachers utilize the group cooperative learning method,which not only helps to improve students’badminton skill level but also cultivates their teamwork spirit,communication skills,and self-management ability unconsciously.In view of this,this paper mainly describes the significance of applying the group cooperative learning method in college badminton teaching,analyzes the current problems in college badminton teaching,and aims to discover effective development strategies for group cooperative learning method in college badminton teaching in order to improve the effectiveness of college badminton teaching.展开更多
N-11-azaartemisinins potentially active against Plasmodium falciparum are designed by combining molecular electrostatic potential (MEP), ligand-receptor interaction, and models built with supervised machine learning m...N-11-azaartemisinins potentially active against Plasmodium falciparum are designed by combining molecular electrostatic potential (MEP), ligand-receptor interaction, and models built with supervised machine learning methods (PCA, HCA, KNN, SIMCA, and SDA). The optimization of molecular structures was performed using the B3LYP/6-31G* approach. MEP maps and ligand-receptor interactions were used to investigate key structural features required for biological activities and likely interactions between N-11-azaartemisinins and heme, respectively. The supervised machine learning methods allowed the separation of the investigated compounds into two classes: cha and cla, with the properties ε<sub>LUMO+1</sub> (one level above lowest unoccupied molecular orbital energy), d(C<sub>6</sub>-C<sub>5</sub>) (distance between C<sub>6</sub> and C<sub>5</sub> atoms in ligands), and TSA (total surface area) responsible for the classification. The insights extracted from the investigation developed and the chemical intuition enabled the design of sixteen new N-11-azaartemisinins (prediction set), moreover, models built with supervised machine learning methods were applied to this prediction set. The result of this application showed twelve new promising N-11-azaartemisinins for synthesis and biological evaluation.展开更多
Acquiring accurate molecular-level information about petroleum is crucial for refining and chemical enterprises to implement the“selection of the optimal processing route”strategy.With the development of data predic...Acquiring accurate molecular-level information about petroleum is crucial for refining and chemical enterprises to implement the“selection of the optimal processing route”strategy.With the development of data prediction systems represented by machine learning,it has become possible for real-time prediction systems of petroleum fraction molecular information to replace analyses such as gas chromatography and mass spectrometry.However,the biggest difficulty lies in acquiring the data required for training the neural network.To address these issues,this work proposes an innovative method that utilizes the Aspen HYSYS and full two-dimensional gas chromatography-time-of-flight mass spectrometry to establish a comprehensive training database.Subsequently,a deep neural network prediction model is developed for heavy distillate oil to predict its composition in terms of molecular structure.After training,the model accurately predicts the molecular composition of catalytically cracked raw oil in a refinery.The validation and test sets exhibit R2 values of 0.99769 and 0.99807,respectively,and the average relative error of molecular composition prediction for raw materials of the catalytic cracking unit is less than 7%.Finally,the SHAP(SHapley Additive ExPlanation)interpretation method is used to disclose the relationship among different variables by performing global and local weight comparisons and correlation analyses.展开更多
Elastography is a non-invasive medical imaging technique to map the spatial variation of elastic properties of soft tissues.The quality of reconstruction results in elastography is highly sensitive to the noise induce...Elastography is a non-invasive medical imaging technique to map the spatial variation of elastic properties of soft tissues.The quality of reconstruction results in elastography is highly sensitive to the noise induced by imaging measurements and processing.To address this issue,we propose a deep learning(DL)model based on conditional Generative Adversarial Networks(cGANs)to improve the quality of nonhomogeneous shear modulus reconstruction.To train this model,we generated a synthetic displacement field with finite element simulation under known nonhomogeneous shear modulus distribution.Both the simulated and experimental displacement fields are used to validate the proposed method.The reconstructed results demonstrate that the DL model with synthetic training data is able to improve the quality of the reconstruction compared with the well-established optimization method.Moreover,we emphasize that our DL model is only trained on synthetic data.This might provide a way to alleviate the challenge of obtaining clinical or experimental data in elastography.Overall,this work addresses several fatal issues in applying the DL technique into elastography,and the proposed method has shown great potential in improving the accuracy of the disease diagnosis in clinical medicine.展开更多
Reservoir identification and production prediction are two of the most important tasks in petroleum exploration and development.Machine learning(ML)methods are used for petroleum-related studies,but have not been appl...Reservoir identification and production prediction are two of the most important tasks in petroleum exploration and development.Machine learning(ML)methods are used for petroleum-related studies,but have not been applied to reservoir identification and production prediction based on reservoir identification.Production forecasting studies are typically based on overall reservoir thickness and lack accuracy when reservoirs contain a water or dry layer without oil production.In this paper,a systematic ML method was developed using classification models for reservoir identification,and regression models for production prediction.The production models are based on the reservoir identification results.To realize the reservoir identification,seven optimized ML methods were used:four typical single ML methods and three ensemble ML methods.These methods classify the reservoir into five types of layers:water,dry and three levels of oil(I oil layer,II oil layer,III oil layer).The validation and test results of these seven optimized ML methods suggest the three ensemble methods perform better than the four single ML methods in reservoir identification.The XGBoost produced the model with the highest accuracy;up to 99%.The effective thickness of I and II oil layers determined during the reservoir identification was fed into the models for predicting production.Effective thickness considers the distribution of the water and the oil resulting in a more reasonable production prediction compared to predictions based on the overall reservoir thickness.To validate the superiority of the ML methods,reference models using overall reservoir thickness were built for comparison.The models based on effective thickness outperformed the reference models in every evaluation metric.The prediction accuracy of the ML models using effective thickness were 10%higher than that of reference model.Without the personal error or data distortion existing in traditional methods,this novel system realizes rapid analysis of data while reducing the time required to resolve reservoir classification and production prediction challenges.The ML models using the effective thickness obtained from reservoir identification were more accurate when predicting oil production compared to previous studies which use overall reservoir thickness.展开更多
In this paper,a new optimal adaptive backstepping control approach for nonlinear systems under deception attacks via reinforcement learning is presented in this paper.The existence of nonlinear terms in the studied sy...In this paper,a new optimal adaptive backstepping control approach for nonlinear systems under deception attacks via reinforcement learning is presented in this paper.The existence of nonlinear terms in the studied system makes it very difficult to design the optimal controller using traditional methods.To achieve optimal control,RL algorithm based on critic–actor architecture is considered for the nonlinear system.Due to the significant security risks of network transmission,the system is vulnerable to deception attacks,which can make all the system state unavailable.By using the attacked states to design coordinate transformation,the harm brought by unknown deception attacks has been overcome.The presented control strategy can ensure that all signals in the closed-loop system are semi-globally ultimately bounded.Finally,the simulation experiment is shown to prove the effectiveness of the strategy.展开更多
Objective: To explore the application effect of flipped classroom combined with problem-based learning teaching method in clinical skills teaching of standardized training for resident doctors of traditional Chinese M...Objective: To explore the application effect of flipped classroom combined with problem-based learning teaching method in clinical skills teaching of standardized training for resident doctors of traditional Chinese Medicine. Methods: The study used the experimental control method. The study lasted from September to November 2022. The subjects of this study were 49 students of standardized training for resident doctors of traditional Chinese Medicine from grades 2020, 2021 and 2022 of Dazhou integrated TCM & Western Medicine Hospital. They were randomly divided into experiment group (25) and control group (24). The experiment group adopted flipped classroom combined with problem-based learning teaching method, and the control group adopted traditional teaching method. The teaching content was 4 basic clinical skill projects, including four diagnoses of traditional Chinese Medicine, cardiopulmonary resuscitation, dressing change procedure, acupuncture and massage. The evaluation method was carried out by comparing the students’ performance and a self-designed questionnaire was used to investigate the students’ evaluation of the teaching method. Results: The test scores of total scores in the experimental group (90.12 ± 5.89) were all higher than those in the control group (81.47 ± 7.96) (t = 4.53, P P Conclusions: The teaching process of the flipped classroom combined with problem-based learning teaching method is conducive to improving the efficiency of classroom teaching, cultivating students’ self-learning ability, and enhancing students’ willingness to learn.展开更多
Predicting the constitutive response of granular soils is a fundamental goal in geomechanics.This paper presents a machine learning(ML)framework for the prediction of the stress-strain behaviour and shearinduced conta...Predicting the constitutive response of granular soils is a fundamental goal in geomechanics.This paper presents a machine learning(ML)framework for the prediction of the stress-strain behaviour and shearinduced contact fabric evolution of an idealised granular material subject to triaxial shearing.The MLbased framework is comprised of a set of mini-triaxial tests which provide a benchmark for the setup and validation of the discrete element method(DEM)model of the granular materials,a parametric DEM simulation programme of virtual triaxial tests which provides datasets of micro-and macro-mechanical information,as well as a multi-layer perceptron(MLP)neural network which is trained and tested using the DEM-based datasets.The ML model only requires the initial void ratio of the granular sample as the input for predicting its constitutive response.The excellent agreement between the ML model prediction and experimental test and DEM simulation results indicates that the MLebased modelling approach is capable of capturing accurately the effects of initial void ratio on the constitutive behaviour of idealised granular materials,bypassing the need to incorporate the complex micromechanics underlying the macroscopic mechanical behaviour of granular materials.Lastly,a detailed comparison between the used MLP model and long short-term memory(LSTM)model was made from the perspective of technical algorithm,prediction accuracy,and computational efficiency.展开更多
Objective:To explore the application effect of flipped classroom combined with case-based learning teaching methods in pharmacoeconomics teaching.Methods:The students majoring in clinical pharmacy in 2019 were selecte...Objective:To explore the application effect of flipped classroom combined with case-based learning teaching methods in pharmacoeconomics teaching.Methods:The students majoring in clinical pharmacy in 2019 were selected as the study subjects,and the cost-effectiveness analysis of different dosage forms of Yinzhihuang in the treatment of neonatal jaundice was selected as the teaching case.The flipped classroom combined with case-based learning teaching method was used to carry out theoretical teaching to the students.After the course,questionnaires were distributed through the Sojump platform to evaluate the teaching effect.Results:The results of the questionnaire showed that 85.71%of the students believed that the flipped classroom combined with case-based learning teaching method was helpful in mobilizing the learning enthusiasm and initiative,and improving the comprehensive application ability of the knowledge of pharmacoeconomics.92.86%of the students think that it is conducive to the understanding and memorization of learning content,as well as the cultivation of teamwork,communication,etc.Conclusion:Flipped classroom combined with case-based learning teaching method can improve students’knowledge mastery,thinking skills,and practical application skills,as well as optimize and improve teachers’teaching levels.展开更多
Tweek atmospherics are extremely low frequency and very low frequency pulse signals with frequency dispersion characteristics that originate from lightning discharges and that propagate in the Earth–ionosphere wavegu...Tweek atmospherics are extremely low frequency and very low frequency pulse signals with frequency dispersion characteristics that originate from lightning discharges and that propagate in the Earth–ionosphere waveguide over long distances.In this study,we developed an automatic method to recognize tweek atmospherics and diagnose the lower ionosphere based on the machine learning method.The differences(automatic−manual)in each ionosphere parameter between the automatic method and the manual method were−0.07±2.73 km,0.03±0.92 cm^(−3),and 91±1,068 km for the ionospheric reflection height(h),equivalent electron densities at reflection heights(Ne),and propagation distance(d),respectively.Moreover,the automatic method is capable of recognizing higher harmonic tweek sferics.The evaluation results of the model suggest that the automatic method is a powerful tool for investigating the long-term variations in the lower ionosphere.展开更多
One of the significant health issues affecting women that impacts their fertility and results in serious health concerns is Polycystic ovarian syndrome(PCOS).Consequently,timely screening of polycystic ovarian syndrom...One of the significant health issues affecting women that impacts their fertility and results in serious health concerns is Polycystic ovarian syndrome(PCOS).Consequently,timely screening of polycystic ovarian syndrome can help in the process of recovery.Finding a method to aid doctors in this procedure was crucial due to the difficulties in detecting this condition.This research aimed to determine whether it is possible to optimize the detection of PCOS utilizing Deep Learning algorithms and methodologies.Additionally,feature selection methods that produce the most important subset of features can speed up calculation and enhance the effectiveness of classifiers.In this research,the tri-stage wrapper method is used because it reduces the computation time.The proposed study for the Automatic diagnosis of PCOS contains preprocessing,data normalization,feature selection,and classification.A dataset with 39 characteristics,including metabolism,neuroimaging,hormones,and biochemical information for 541 subjects,was employed in this scenario.To start,this research pre-processed the information.Next for feature selection,a tri-stage wrapper method such as Mutual Information,ReliefF,Chi-Square,and Xvariance is used.Then,various classification methods are tested and trained.Deep learning techniques including convolutional neural network(CNN),multi-layer perceptron(MLP),Recurrent neural network(RNN),and Bi long short-term memory(Bi-LSTM)are utilized for categorization.The experimental finding demonstrates that with effective feature extraction process using tri stage wrapper method+CNN delivers the highest precision(97%),high accuracy(98.67%),and recall(89%)when compared with other machine learning algorithms.展开更多
In modern transportation,pavement is one of the most important civil infrastructures for the movement of vehicles and pedestrians.Pavement service quality and service life are of great importance for civil engineers a...In modern transportation,pavement is one of the most important civil infrastructures for the movement of vehicles and pedestrians.Pavement service quality and service life are of great importance for civil engineers as they directly affect the regular service for the users.Therefore,monitoring the health status of pavement before irreversible damage occurs is essential for timely maintenance,which in turn ensures public transportation safety.Many pavement damages can be detected and analyzed by monitoring the structure dynamic responses and evaluating road surface conditions.Advanced technologies can be employed for the collection and analysis of such data,including various intrusive sensing techniques,image processing techniques,and machine learning methods.This review summarizes the state-ofthe-art of these three technologies in pavement engineering in recent years and suggests possible developments for future pavement monitoring and analysis based on these approaches.展开更多
A large database is desired for machine learning(ML) technology to make accurate predictions of materials physicochemical properties based on their molecular structure.When a large database is not available,the develo...A large database is desired for machine learning(ML) technology to make accurate predictions of materials physicochemical properties based on their molecular structure.When a large database is not available,the development of proper featurization method based on physicochemical nature of target proprieties can improve the predictive power of ML models with a smaller database.In this work,we show that two new featurization methods,volume occupation spatial matrix and heat contribution spatial matrix,can improve the accuracy in predicting energetic materials' crystal density(ρ_(crystal)) and solid phase enthalpy of formation(H_(f,solid)) using a database containing 451 energetic molecules.Their mean absolute errors are reduced from 0.048 g/cm~3 and 24.67 kcal/mol to 0.035 g/cm~3 and 9.66 kcal/mol,respectively.By leave-one-out-cross-validation,the newly developed ML models can be used to determine the performance of most kinds of energetic materials except cubanes.Our ML models are applied to predict ρ_(crystal) and H_(f,solid) of CHON-based molecules of the 150 million sized PubChem database,and screened out 56 candidates with competitive detonation performance and reasonable chemical structures.With further improvement in future,spatial matrices have the potential of becoming multifunctional ML simulation tools that could provide even better predictions in wider fields of materials science.展开更多
Several millions of people suffer from Parkinson’s disease globally.Parkinson’s affects about 1%of people over 60 and its symptoms increase with age.The voice may be affected and patients experience abnormalities in...Several millions of people suffer from Parkinson’s disease globally.Parkinson’s affects about 1%of people over 60 and its symptoms increase with age.The voice may be affected and patients experience abnormalities in speech that might not be noticed by listeners,but which could be analyzed using recorded speech signals.With the huge advancements of technology,the medical data has increased dramatically,and therefore,there is a need to apply data mining and machine learning methods to extract new knowledge from this data.Several classification methods were used to analyze medical data sets and diagnostic problems,such as Parkinson’s Disease(PD).In addition,to improve the performance of classification,feature selection methods have been extensively used in many fields.This paper aims to propose a comprehensive approach to enhance the prediction of PD using several machine learning methods with different feature selection methods such as filter-based and wrapper-based.The dataset includes 240 recodes with 46 acoustic features extracted from3 voice recording replications for 80 patients.The experimental results showed improvements when wrapper-based features selection method was used with K-NN classifier with accuracy of 88.33%.The best obtained results were compared with other studies and it was found that this study provides comparable and superior results.展开更多
With the continuous development of national‘reforms and opening-up’policy and development of economic globalization,learning and application of foreign languages are becoming increasingly important.Society needs a l...With the continuous development of national‘reforms and opening-up’policy and development of economic globalization,learning and application of foreign languages are becoming increasingly important.Society needs a large number of professional linguistic workers.Therefore,there are higher requirements for new era higher learning institutes which serve as training base for cultivating linguistic talents.Linguistic talents must possess very strong overall quality and skill to meet these requirements.In this context,this study carried out an in-depth analysis and research on translation method commonly used in German language teaching,and communicative method which is increasingly popular in recent years,to contribute to cultivation of German linguistic talents in higher learning institutes of China.展开更多
The goal of this research is to explore a more successful method for Mainland Chinese students to learn English.This newmethod will be illustrated by using the experiences of my daughter while a student in an elementa...The goal of this research is to explore a more successful method for Mainland Chinese students to learn English.This newmethod will be illustrated by using the experiences of my daughter while a student in an elementary school in the United States for oneyear.From the analysis of her learning experiences,the following conclusions were drawn:1) Immerse language learning is important tolanguage input.2) Phonics is an effective tool to improve reading for Chinese English展开更多
基金supported by a Major Research Project in Higher Education Institutions in Henan Province,with Project Number 23A560015.
文摘A new approach for flexoelectricmaterial shape optimization is proposed in this study.In this work,a proxymodel based on artificial neural network(ANN)is used to solve the parameter optimization and shape optimization problems.To improve the fitting ability of the neural network,we use the idea of pre-training to determine the structure of the neural network and combine different optimizers for training.The isogeometric analysis-finite element method(IGA-FEM)is used to discretize the flexural theoretical formulas and obtain samples,which helps ANN to build a proxy model from the model shape to the target value.The effectiveness of the proposed method is verified through two numerical examples of parameter optimization and one numerical example of shape optimization.
文摘In college badminton teaching,teachers utilize the group cooperative learning method,which not only helps to improve students’badminton skill level but also cultivates their teamwork spirit,communication skills,and self-management ability unconsciously.In view of this,this paper mainly describes the significance of applying the group cooperative learning method in college badminton teaching,analyzes the current problems in college badminton teaching,and aims to discover effective development strategies for group cooperative learning method in college badminton teaching in order to improve the effectiveness of college badminton teaching.
文摘N-11-azaartemisinins potentially active against Plasmodium falciparum are designed by combining molecular electrostatic potential (MEP), ligand-receptor interaction, and models built with supervised machine learning methods (PCA, HCA, KNN, SIMCA, and SDA). The optimization of molecular structures was performed using the B3LYP/6-31G* approach. MEP maps and ligand-receptor interactions were used to investigate key structural features required for biological activities and likely interactions between N-11-azaartemisinins and heme, respectively. The supervised machine learning methods allowed the separation of the investigated compounds into two classes: cha and cla, with the properties ε<sub>LUMO+1</sub> (one level above lowest unoccupied molecular orbital energy), d(C<sub>6</sub>-C<sub>5</sub>) (distance between C<sub>6</sub> and C<sub>5</sub> atoms in ligands), and TSA (total surface area) responsible for the classification. The insights extracted from the investigation developed and the chemical intuition enabled the design of sixteen new N-11-azaartemisinins (prediction set), moreover, models built with supervised machine learning methods were applied to this prediction set. The result of this application showed twelve new promising N-11-azaartemisinins for synthesis and biological evaluation.
基金the National Natural Science Foundation of China(22108307)the Natural Science Foundation of Shandong Province(ZR2020KB006)the Outstanding Youth Fund of Shandong Provincial Natural Science Foundation(ZR2020YQ17).
文摘Acquiring accurate molecular-level information about petroleum is crucial for refining and chemical enterprises to implement the“selection of the optimal processing route”strategy.With the development of data prediction systems represented by machine learning,it has become possible for real-time prediction systems of petroleum fraction molecular information to replace analyses such as gas chromatography and mass spectrometry.However,the biggest difficulty lies in acquiring the data required for training the neural network.To address these issues,this work proposes an innovative method that utilizes the Aspen HYSYS and full two-dimensional gas chromatography-time-of-flight mass spectrometry to establish a comprehensive training database.Subsequently,a deep neural network prediction model is developed for heavy distillate oil to predict its composition in terms of molecular structure.After training,the model accurately predicts the molecular composition of catalytically cracked raw oil in a refinery.The validation and test sets exhibit R2 values of 0.99769 and 0.99807,respectively,and the average relative error of molecular composition prediction for raw materials of the catalytic cracking unit is less than 7%.Finally,the SHAP(SHapley Additive ExPlanation)interpretation method is used to disclose the relationship among different variables by performing global and local weight comparisons and correlation analyses.
基金National Natural Science Foundation of China (12002075)National Key Research and Development Project (2021YFB3300601)Natural Science Foundation of Liaoning Province in China (2021-MS-128).
文摘Elastography is a non-invasive medical imaging technique to map the spatial variation of elastic properties of soft tissues.The quality of reconstruction results in elastography is highly sensitive to the noise induced by imaging measurements and processing.To address this issue,we propose a deep learning(DL)model based on conditional Generative Adversarial Networks(cGANs)to improve the quality of nonhomogeneous shear modulus reconstruction.To train this model,we generated a synthetic displacement field with finite element simulation under known nonhomogeneous shear modulus distribution.Both the simulated and experimental displacement fields are used to validate the proposed method.The reconstructed results demonstrate that the DL model with synthetic training data is able to improve the quality of the reconstruction compared with the well-established optimization method.Moreover,we emphasize that our DL model is only trained on synthetic data.This might provide a way to alleviate the challenge of obtaining clinical or experimental data in elastography.Overall,this work addresses several fatal issues in applying the DL technique into elastography,and the proposed method has shown great potential in improving the accuracy of the disease diagnosis in clinical medicine.
文摘Reservoir identification and production prediction are two of the most important tasks in petroleum exploration and development.Machine learning(ML)methods are used for petroleum-related studies,but have not been applied to reservoir identification and production prediction based on reservoir identification.Production forecasting studies are typically based on overall reservoir thickness and lack accuracy when reservoirs contain a water or dry layer without oil production.In this paper,a systematic ML method was developed using classification models for reservoir identification,and regression models for production prediction.The production models are based on the reservoir identification results.To realize the reservoir identification,seven optimized ML methods were used:four typical single ML methods and three ensemble ML methods.These methods classify the reservoir into five types of layers:water,dry and three levels of oil(I oil layer,II oil layer,III oil layer).The validation and test results of these seven optimized ML methods suggest the three ensemble methods perform better than the four single ML methods in reservoir identification.The XGBoost produced the model with the highest accuracy;up to 99%.The effective thickness of I and II oil layers determined during the reservoir identification was fed into the models for predicting production.Effective thickness considers the distribution of the water and the oil resulting in a more reasonable production prediction compared to predictions based on the overall reservoir thickness.To validate the superiority of the ML methods,reference models using overall reservoir thickness were built for comparison.The models based on effective thickness outperformed the reference models in every evaluation metric.The prediction accuracy of the ML models using effective thickness were 10%higher than that of reference model.Without the personal error or data distortion existing in traditional methods,this novel system realizes rapid analysis of data while reducing the time required to resolve reservoir classification and production prediction challenges.The ML models using the effective thickness obtained from reservoir identification were more accurate when predicting oil production compared to previous studies which use overall reservoir thickness.
基金supported in part by the National Key R&D Program of China under Grants 2021YFE0206100in part by the National Natural Science Foundation of China under Grant 62073321+2 种基金in part by National Defense Basic Scientific Research Program JCKY2019203C029in part by the Science and Technology Development Fund,Macao SAR under Grants FDCT-22-009-MISE,0060/2021/A2 and 0015/2020/AMJin part by the financial support from the National Defense Basic Scientific Research Project(JCKY2020130C025).
文摘In this paper,a new optimal adaptive backstepping control approach for nonlinear systems under deception attacks via reinforcement learning is presented in this paper.The existence of nonlinear terms in the studied system makes it very difficult to design the optimal controller using traditional methods.To achieve optimal control,RL algorithm based on critic–actor architecture is considered for the nonlinear system.Due to the significant security risks of network transmission,the system is vulnerable to deception attacks,which can make all the system state unavailable.By using the attacked states to design coordinate transformation,the harm brought by unknown deception attacks has been overcome.The presented control strategy can ensure that all signals in the closed-loop system are semi-globally ultimately bounded.Finally,the simulation experiment is shown to prove the effectiveness of the strategy.
文摘Objective: To explore the application effect of flipped classroom combined with problem-based learning teaching method in clinical skills teaching of standardized training for resident doctors of traditional Chinese Medicine. Methods: The study used the experimental control method. The study lasted from September to November 2022. The subjects of this study were 49 students of standardized training for resident doctors of traditional Chinese Medicine from grades 2020, 2021 and 2022 of Dazhou integrated TCM & Western Medicine Hospital. They were randomly divided into experiment group (25) and control group (24). The experiment group adopted flipped classroom combined with problem-based learning teaching method, and the control group adopted traditional teaching method. The teaching content was 4 basic clinical skill projects, including four diagnoses of traditional Chinese Medicine, cardiopulmonary resuscitation, dressing change procedure, acupuncture and massage. The evaluation method was carried out by comparing the students’ performance and a self-designed questionnaire was used to investigate the students’ evaluation of the teaching method. Results: The test scores of total scores in the experimental group (90.12 ± 5.89) were all higher than those in the control group (81.47 ± 7.96) (t = 4.53, P P Conclusions: The teaching process of the flipped classroom combined with problem-based learning teaching method is conducive to improving the efficiency of classroom teaching, cultivating students’ self-learning ability, and enhancing students’ willingness to learn.
基金This study was supported by General Research Fund from the Research Grants Council of the Hong Kong SAR(Grant Nos.CityU 11201020 and 11207321)the National Natural Science Foundation of China(Grant No.51779213)as well as Contract Research Project(Ref.No.CEDD STD-30-2030-1-12R)from the Geotechnical Engineering Office.
文摘Predicting the constitutive response of granular soils is a fundamental goal in geomechanics.This paper presents a machine learning(ML)framework for the prediction of the stress-strain behaviour and shearinduced contact fabric evolution of an idealised granular material subject to triaxial shearing.The MLbased framework is comprised of a set of mini-triaxial tests which provide a benchmark for the setup and validation of the discrete element method(DEM)model of the granular materials,a parametric DEM simulation programme of virtual triaxial tests which provides datasets of micro-and macro-mechanical information,as well as a multi-layer perceptron(MLP)neural network which is trained and tested using the DEM-based datasets.The ML model only requires the initial void ratio of the granular sample as the input for predicting its constitutive response.The excellent agreement between the ML model prediction and experimental test and DEM simulation results indicates that the MLebased modelling approach is capable of capturing accurately the effects of initial void ratio on the constitutive behaviour of idealised granular materials,bypassing the need to incorporate the complex micromechanics underlying the macroscopic mechanical behaviour of granular materials.Lastly,a detailed comparison between the used MLP model and long short-term memory(LSTM)model was made from the perspective of technical algorithm,prediction accuracy,and computational efficiency.
基金2022 Medical Innovation and Development Project of Lanzhou University(lzuyxcx-2022-40)2022 Education and Teaching Reform Research Project of Lanzhou University General Project(202201)The Foundation of the First Hospital of Lanzhou University(ldyyyn 2021-92)。
文摘Objective:To explore the application effect of flipped classroom combined with case-based learning teaching methods in pharmacoeconomics teaching.Methods:The students majoring in clinical pharmacy in 2019 were selected as the study subjects,and the cost-effectiveness analysis of different dosage forms of Yinzhihuang in the treatment of neonatal jaundice was selected as the teaching case.The flipped classroom combined with case-based learning teaching method was used to carry out theoretical teaching to the students.After the course,questionnaires were distributed through the Sojump platform to evaluate the teaching effect.Results:The results of the questionnaire showed that 85.71%of the students believed that the flipped classroom combined with case-based learning teaching method was helpful in mobilizing the learning enthusiasm and initiative,and improving the comprehensive application ability of the knowledge of pharmacoeconomics.92.86%of the students think that it is conducive to the understanding and memorization of learning content,as well as the cultivation of teamwork,communication,etc.Conclusion:Flipped classroom combined with case-based learning teaching method can improve students’knowledge mastery,thinking skills,and practical application skills,as well as optimize and improve teachers’teaching levels.
基金supported by the Chinese Academy of Sciences(CAS)Project of Stable Support for Youth Team in Basic Research Field(Grant No.YSRR-018)the National Key R&D Program of China(Grant No.2019YFC1510103)+1 种基金the National Natural Science Foundation of China(Grant Nos.41875006 and U1938115)the Chinese Meridian Project,and the International Partnership Program of CAS(Grant No.183311KYSB20200003).
文摘Tweek atmospherics are extremely low frequency and very low frequency pulse signals with frequency dispersion characteristics that originate from lightning discharges and that propagate in the Earth–ionosphere waveguide over long distances.In this study,we developed an automatic method to recognize tweek atmospherics and diagnose the lower ionosphere based on the machine learning method.The differences(automatic−manual)in each ionosphere parameter between the automatic method and the manual method were−0.07±2.73 km,0.03±0.92 cm^(−3),and 91±1,068 km for the ionospheric reflection height(h),equivalent electron densities at reflection heights(Ne),and propagation distance(d),respectively.Moreover,the automatic method is capable of recognizing higher harmonic tweek sferics.The evaluation results of the model suggest that the automatic method is a powerful tool for investigating the long-term variations in the lower ionosphere.
基金The authors extend their appreciation to the Deputyship for Research&Innovation,Ministry of Education in Saudi Arabia for funding this research work through Project Number WE-44-0033.
文摘One of the significant health issues affecting women that impacts their fertility and results in serious health concerns is Polycystic ovarian syndrome(PCOS).Consequently,timely screening of polycystic ovarian syndrome can help in the process of recovery.Finding a method to aid doctors in this procedure was crucial due to the difficulties in detecting this condition.This research aimed to determine whether it is possible to optimize the detection of PCOS utilizing Deep Learning algorithms and methodologies.Additionally,feature selection methods that produce the most important subset of features can speed up calculation and enhance the effectiveness of classifiers.In this research,the tri-stage wrapper method is used because it reduces the computation time.The proposed study for the Automatic diagnosis of PCOS contains preprocessing,data normalization,feature selection,and classification.A dataset with 39 characteristics,including metabolism,neuroimaging,hormones,and biochemical information for 541 subjects,was employed in this scenario.To start,this research pre-processed the information.Next for feature selection,a tri-stage wrapper method such as Mutual Information,ReliefF,Chi-Square,and Xvariance is used.Then,various classification methods are tested and trained.Deep learning techniques including convolutional neural network(CNN),multi-layer perceptron(MLP),Recurrent neural network(RNN),and Bi long short-term memory(Bi-LSTM)are utilized for categorization.The experimental finding demonstrates that with effective feature extraction process using tri stage wrapper method+CNN delivers the highest precision(97%),high accuracy(98.67%),and recall(89%)when compared with other machine learning algorithms.
基金supported by the National Key R&D Program of China(2017YFF0205600)the International Research Cooperation Seed Fund of Beijing University of Technology(2018A08)+1 种基金Science and Technology Project of Beijing Municipal Commission of Transport(2018-kjc-01-213)the Construction of Service Capability of Scientific and Technological Innovation-Municipal Level of Fundamental Research Funds(Scientific Research Categories)of Beijing City(PXM2019_014204_500032).
文摘In modern transportation,pavement is one of the most important civil infrastructures for the movement of vehicles and pedestrians.Pavement service quality and service life are of great importance for civil engineers as they directly affect the regular service for the users.Therefore,monitoring the health status of pavement before irreversible damage occurs is essential for timely maintenance,which in turn ensures public transportation safety.Many pavement damages can be detected and analyzed by monitoring the structure dynamic responses and evaluating road surface conditions.Advanced technologies can be employed for the collection and analysis of such data,including various intrusive sensing techniques,image processing techniques,and machine learning methods.This review summarizes the state-ofthe-art of these three technologies in pavement engineering in recent years and suggests possible developments for future pavement monitoring and analysis based on these approaches.
基金support from the Ministry of Education(MOE) Singapore Tier 1 (RG8/20)。
文摘A large database is desired for machine learning(ML) technology to make accurate predictions of materials physicochemical properties based on their molecular structure.When a large database is not available,the development of proper featurization method based on physicochemical nature of target proprieties can improve the predictive power of ML models with a smaller database.In this work,we show that two new featurization methods,volume occupation spatial matrix and heat contribution spatial matrix,can improve the accuracy in predicting energetic materials' crystal density(ρ_(crystal)) and solid phase enthalpy of formation(H_(f,solid)) using a database containing 451 energetic molecules.Their mean absolute errors are reduced from 0.048 g/cm~3 and 24.67 kcal/mol to 0.035 g/cm~3 and 9.66 kcal/mol,respectively.By leave-one-out-cross-validation,the newly developed ML models can be used to determine the performance of most kinds of energetic materials except cubanes.Our ML models are applied to predict ρ_(crystal) and H_(f,solid) of CHON-based molecules of the 150 million sized PubChem database,and screened out 56 candidates with competitive detonation performance and reasonable chemical structures.With further improvement in future,spatial matrices have the potential of becoming multifunctional ML simulation tools that could provide even better predictions in wider fields of materials science.
基金This research was funded by the Deputyship for Research&Innovation,Ministry of Education in Saudi Arabia under the Project Number(77/442).
文摘Several millions of people suffer from Parkinson’s disease globally.Parkinson’s affects about 1%of people over 60 and its symptoms increase with age.The voice may be affected and patients experience abnormalities in speech that might not be noticed by listeners,but which could be analyzed using recorded speech signals.With the huge advancements of technology,the medical data has increased dramatically,and therefore,there is a need to apply data mining and machine learning methods to extract new knowledge from this data.Several classification methods were used to analyze medical data sets and diagnostic problems,such as Parkinson’s Disease(PD).In addition,to improve the performance of classification,feature selection methods have been extensively used in many fields.This paper aims to propose a comprehensive approach to enhance the prediction of PD using several machine learning methods with different feature selection methods such as filter-based and wrapper-based.The dataset includes 240 recodes with 46 acoustic features extracted from3 voice recording replications for 80 patients.The experimental results showed improvements when wrapper-based features selection method was used with K-NN classifier with accuracy of 88.33%.The best obtained results were compared with other studies and it was found that this study provides comparable and superior results.
文摘With the continuous development of national‘reforms and opening-up’policy and development of economic globalization,learning and application of foreign languages are becoming increasingly important.Society needs a large number of professional linguistic workers.Therefore,there are higher requirements for new era higher learning institutes which serve as training base for cultivating linguistic talents.Linguistic talents must possess very strong overall quality and skill to meet these requirements.In this context,this study carried out an in-depth analysis and research on translation method commonly used in German language teaching,and communicative method which is increasingly popular in recent years,to contribute to cultivation of German linguistic talents in higher learning institutes of China.
文摘The goal of this research is to explore a more successful method for Mainland Chinese students to learn English.This newmethod will be illustrated by using the experiences of my daughter while a student in an elementary school in the United States for oneyear.From the analysis of her learning experiences,the following conclusions were drawn:1) Immerse language learning is important tolanguage input.2) Phonics is an effective tool to improve reading for Chinese English