The mixed distribution model is often used to extract information from heteroge-neous data and perform modeling analysis.When the density function of mixed distribution is complicated or the variable dimension is high...The mixed distribution model is often used to extract information from heteroge-neous data and perform modeling analysis.When the density function of mixed distribution is complicated or the variable dimension is high,it usually brings challenges to the parameter es-timation of the mixed distribution model.The application of MM algorithm can avoid complex expectation calculations,and can also solve the problem of high-dimensional optimization by decomposing the objective function.In this paper,MM algorithm is applied to the parameter estimation problem of mixed distribution model.The method of assembly and decomposition is used to construct the substitute function with separable parameters,which avoids the problems of complex expectation calculations and the inversion of high-dimensional matrices.展开更多
Celiac disease(CD)is an autoimmune disease of the small bowel induced by ingestion of wheat,rye and barley.Current guidelines indicate histological analysis on at least four duodenal biopsies as the only way to diagno...Celiac disease(CD)is an autoimmune disease of the small bowel induced by ingestion of wheat,rye and barley.Current guidelines indicate histological analysis on at least four duodenal biopsies as the only way to diagnose CD.These indications are based on the conception of the inability of standard endoscopy to make diagnosis of CD and/or to drive biopsy sampling.Over the last years,technology development of endoscopic devices has greatly ameliorated the accuracy of macroscopic evaluation of duodenal villous pattern,increasing the diagnostic power of endoscopy of CD.The aim of this paper is to review the new endoscopic tools and procedures proved to be useful in the diagnosis of CD,such as chromoendoscopy,Fujinon Intelligent Chromo Endoscopy,Narrow Band Imaging,Optical Coherence Tomography,Water-Immersion Technique,confocal laser endomicroscopy,high-resolution magnification endoscopy,capsule endoscopy and I-Scan technology.展开更多
Enterprises engaging in collaboration with competitors can increase their technological diversity and release a new product innovation, but also full of challenges. This complexity of co-opetition relationship require...Enterprises engaging in collaboration with competitors can increase their technological diversity and release a new product innovation, but also full of challenges. This complexity of co-opetition relationship requirements academia and enterprises to clarify the problem of competitive technology alliance risk formation mechanism, making the risk control to dispose. Based on the perspective of resources and capabilities, this paper firstly puts forward the double helix model of alliances＇ evolution on resources and capabilities ; then, with the deepe- ning of the cooperation, this evolutionary process leads to different innovation risk： opportunism, R and D inte- gration risk and flexible loss risk; next, analyzing the corresponding management path and constructing the conceptual framework of risk management mechanism to help enterprise using the co-opetition relationship to reduce risk and improve the potential competitive advantage.展开更多
This paper evaluated performance of motor insurance companies in Nigeria. The objectives were to determine the following: 1) significant effects of claims settlements on motor insurance firms’ earned premium;2) diffe...This paper evaluated performance of motor insurance companies in Nigeria. The objectives were to determine the following: 1) significant effects of claims settlements on motor insurance firms’ earned premium;2) differences in managerial/technological capabilities among the companies and 3) effects of policy (or time effect) on insurance firms’ output within the study </span><span style="font-family:Verdana;">period. Panel data obtained for this study comprised operational data on</span><span style="font-family:Verdana;"> premium earned and direct claims settlement by these companies over a period </span><span style="font-family:Verdana;">of six (6) years. Using panel data statistical models, we found that direct</span><span style="font-family:Verdana;"> claims settlement negatively affected insurance companies’ earned premium. Also, </span><span style="font-family:Verdana;">significant differences in technological and managerial capabilities were </span><span style="font-family:Verdana;">found to exist among the companies, though only one company exhibited this heterogeneity. Besides, there were no policy impacts (or time effect) on vehicle insurance firms’ output in the study period. Policy implications of the results were discussed.展开更多
基金Supported by the National Natural Science Foundation of China(12261108)the General Program of Basic Research Programs of Yunnan Province(202401AT070126)+1 种基金the Yunnan Key Laboratory of Modern Analytical Mathematics and Applications(202302AN360007)the Cross-integration Innovation team of modern Applied Mathematics and Life Sciences in Yunnan Province,China(202405AS350003).
文摘The mixed distribution model is often used to extract information from heteroge-neous data and perform modeling analysis.When the density function of mixed distribution is complicated or the variable dimension is high,it usually brings challenges to the parameter es-timation of the mixed distribution model.The application of MM algorithm can avoid complex expectation calculations,and can also solve the problem of high-dimensional optimization by decomposing the objective function.In this paper,MM algorithm is applied to the parameter estimation problem of mixed distribution model.The method of assembly and decomposition is used to construct the substitute function with separable parameters,which avoids the problems of complex expectation calculations and the inversion of high-dimensional matrices.
文摘Celiac disease(CD)is an autoimmune disease of the small bowel induced by ingestion of wheat,rye and barley.Current guidelines indicate histological analysis on at least four duodenal biopsies as the only way to diagnose CD.These indications are based on the conception of the inability of standard endoscopy to make diagnosis of CD and/or to drive biopsy sampling.Over the last years,technology development of endoscopic devices has greatly ameliorated the accuracy of macroscopic evaluation of duodenal villous pattern,increasing the diagnostic power of endoscopy of CD.The aim of this paper is to review the new endoscopic tools and procedures proved to be useful in the diagnosis of CD,such as chromoendoscopy,Fujinon Intelligent Chromo Endoscopy,Narrow Band Imaging,Optical Coherence Tomography,Water-Immersion Technique,confocal laser endomicroscopy,high-resolution magnification endoscopy,capsule endoscopy and I-Scan technology.
文摘Enterprises engaging in collaboration with competitors can increase their technological diversity and release a new product innovation, but also full of challenges. This complexity of co-opetition relationship requirements academia and enterprises to clarify the problem of competitive technology alliance risk formation mechanism, making the risk control to dispose. Based on the perspective of resources and capabilities, this paper firstly puts forward the double helix model of alliances＇ evolution on resources and capabilities ; then, with the deepe- ning of the cooperation, this evolutionary process leads to different innovation risk： opportunism, R and D inte- gration risk and flexible loss risk; next, analyzing the corresponding management path and constructing the conceptual framework of risk management mechanism to help enterprise using the co-opetition relationship to reduce risk and improve the potential competitive advantage.
文摘This paper evaluated performance of motor insurance companies in Nigeria. The objectives were to determine the following: 1) significant effects of claims settlements on motor insurance firms’ earned premium;2) differences in managerial/technological capabilities among the companies and 3) effects of policy (or time effect) on insurance firms’ output within the study </span><span style="font-family:Verdana;">period. Panel data obtained for this study comprised operational data on</span><span style="font-family:Verdana;"> premium earned and direct claims settlement by these companies over a period </span><span style="font-family:Verdana;">of six (6) years. Using panel data statistical models, we found that direct</span><span style="font-family:Verdana;"> claims settlement negatively affected insurance companies’ earned premium. Also, </span><span style="font-family:Verdana;">significant differences in technological and managerial capabilities were </span><span style="font-family:Verdana;">found to exist among the companies, though only one company exhibited this heterogeneity. Besides, there were no policy impacts (or time effect) on vehicle insurance firms’ output in the study period. Policy implications of the results were discussed.
