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Using a novel cellular platform to optimize CRISPR/CAS9 technology for the gene therapy of AIDS 被引量:2
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作者 Jingjin He Thanutra Zhang Xuemei Fu 《Protein & Cell》 SCIE CAS CSCD 2017年第11期848-852,共5页
Dear Editor,Despite tremendous effort devoted to the development of antiretroviral therapies to combat HIV over the past decades, AIDS remains one of the most important global infectious diseases. According to UNAIDS ... Dear Editor,Despite tremendous effort devoted to the development of antiretroviral therapies to combat HIV over the past decades, AIDS remains one of the most important global infectious diseases. According to UNAIDS report on the global AIDS epidemic in 2016, the estimated number of people living with HIV rose from 7.5 million in 2010 to 36.7 million in 2015. Furthermore, drug-resistance HIV strains have recently been reported (Wensing et al., 2017). Therefore, it is important to develop new therapies to eliminate HIV in the patients. Immortalized cell lines representing the major targets of HIV in human are important for HIV research and therapeutic development. 展开更多
关键词 novel cellular platform optimize CRISPR/CAS9 technology the gene therapy of AIDS
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临床细胞治疗技术平台设计探讨 被引量:1
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作者 杨润宇 《化工与医药工程》 2015年第5期32-35,共4页
根据DB 31/T 687—2013规范要求,从工艺专业角度对临床细胞治疗技术平台设计进行简述,并通过一个临床细胞治疗技术平台方案设计的案例,结合相关规范,阐述该技术平台设计要求。着重讨论如何使该类工程设计符合规范要求。
关键词 临床细胞治疗技术平台 工艺设计 设施配制要求 规范要求
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