Comparative Analysis of the Efficacy of Transabdominal Pre-Peritoneal Vs Open Tension-Free Hernia Repair in Treating Inguinal Hernia

Objective:To investigate and analyze the clinical outcomes of inguinal hernia patients treated with transabdominal pre-peritoneal repair(TAPP)versus open tension-free hernia repair.Methods:The study was carried out from January 2021 to August 2023,and a total of 50 inguinal hernia patients were selected for this study.The patients were randomly divided into a study group(n=25)and a control group(n=25)by the numerical table method.The patients in the control group were treated with open tension-free hernia repair,whereas the patients in the study group were treated with TAPP.The surgical and postoperative recovery indexes,complication rates,and recurrence rates of the two groups were compared.Results:There was no significant difference in the operative time and intraoperative blood loss between the two groups(P>0.05),and the postoperative feeding time,time out of bed,and hospitalization time of the study group were shorter than those of the control group(P<0.05);the incidence rate of postoperative complications in the study group was lower than that in the control group(P<0.05);and there was no significant difference in the recurrence rate of the two groups after operation(P>0.05).Conclusion:Compared to open tension-free hernia repair,TAPP offers a shorter postoperative recovery duration and hospitalization time,and reduces the incidence of complications.Therefore,this surgical method should be popularized in the treatment of inguinal hernia.

Analysis of the Effect and Efficiency of Tension- Free Hernia Repair and Traditional Surgery in The Treatment of Hernia

Objective: To analyze the efficiency of tension-free hernia repair and traditional surgery in the treatment of hernia. Methods: A total of 80 patients with hernias were selected and randomly into a control group (traditional hernia repair) and an observation group (tension-free hernia repair), of 40 cases each. The perioperative indicators, pain, physiological stress indicators, complications, and recurrence rates between the two groups were compared. Results: The perioperative indexes of the observation group were better than those of the control group (P < 0.05). The postoperative pain score, postoperative physiological stress index level, incidence of complications, and recurrence rate of the observation group were lower than those of the control group (P < 0.05). Conclusion: In the surgical treatment of hernia, tension-free hernia repair was less traumatic and had a better effect than traditional hernia repair.

Hernia Repair during Cesarean Section—Compliance Matters: Tension-Free Tissue Repair

Purpose: Simultaneous surgeries are increasingly applied in all surgical fields. They bring cost and health advantages to the patient and the economy. Pregnancy is one of the risk factors of hernia in females. We conducted a study for simultaneous tissue repairs of inguinal and umbilical hernias during cesarean section. Methods: Between January 1997 and August 2013 we have operated 42 patients with 45 hernias either umbilical or inguinal. We performed the repairs from the Pfannenstiel incision. Data about maternal age, parity, cause of cesarean section, length of operation, length of stay, complications and patient satisfaction were collected. Results: Within this period there were 19,904 deliveries in total. Incidence of umbilical hernia was found 0.2% and it was 0.1% for the inguinal hernia. Simultaneous hernia repairs significantly prolonged the operative time. There was no recurrence and complication. Conclusions: Our results showed that hernia repair can be performed without any additional risks during cesarean section. We believe that if there is an indication for cesarean section in a pregnancy complicated by an abdominal wall hernia, patients should be informed that it would be safe and effective to repair these hernias during cesarean section. This approach also enables tension-free pure tissue repairs.

Analysis of Ultrasound-guided Ilioinguinal and Iliohypogastric Nerve Block in Tension-Free Inguinal Hernia Repair in Elderly Patients

Objective:To explore the value of ultrasound-guided ilioinguinal and iliohypogastric nerve block(IINB)in tension-free inguinal hernia repair in elderly patients.Methods:A total of 70 elderly patients with tension-free inguinal hernia repair who treated in the hospital from April 2018 to November 2019 were selected and divided into two groups according to the random number table method,with 35 cases each.The control group underwent infiltration of local anesthesia(LA),and the study group added with IINB.The visual analogue scale(VAS)scores of the two groups of patients were compared.Results:The VAS score of the study group when pulling the hernia sac was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:IINB has good analgesic effect in tensionfree inguinal hernia repair in elderly patients,and it is worth promoting.

Current trends in laparoscopic groin hernia repair: A review

Hernia is a common problem of the modern world with its incidence more in developing countries. Inguinal hernia is the most common groin hernia repaired worldwide. With advancement in technology operative techniques of repair have also evolved. A Pub Med and COCHRANE database search was accomplished in this regard to establish the current status of laparoscopic inguinal hernia repair in view of recent published literature. Published literature support that laparoscopic hernia repair is best suited for recurrent and bilateral inguinal hernia although it may be offered for primary inguinal hernia if expertise is available.

Analysis of the Causes of Chronic Pain after Inguinal Hernia Repair without Tension and Its Prevention and Treatment

Purpose: Analyzing the causes of pain after tension-free repair in the inguinal hernia, and propose corresponding treatment strategies. Results: The patients in this group were followed up for 3 - 12 months. A total of 5 patients still had pain relief within 3 months after surgery. Further treatment was needed, and the incidence rate was 5%. Conclusion: Skilled surgical procedures are performed in patients with local anesthesia, and some of the absorbable repair materials can be used. The improved patch fixation and extra peritoneal repair can reduce the pain after inguinal hernia repair without tension.

Perioperative Local Cooling Reduce Significantly Early Pain after Open Inguinal Hernia Repair:A Prospective Randomized Study

Pain and local complications are the major determinants of outcome after inguinal hernia repair. To evaluate the respective impact of peri-operative cooling of surgical site and usual care after open inguinal hernia repair, we performed a prospective randomized study. Methods: One hundred and eight consecutive patients with primary unilateral inguinal hernia were included the study. Repair was performed by local direct access during ambulatory surgery. The first study group underwent standard pre- and postoperative local care (control group). In the second group (cold compress group), a single-use disposable sterile cold compress was applied on the surgical site for at least 30 minutes before and 2 hours after surgery. Primary endpoints were immediate postoperative pain using a visual analogue scale, and local complications. Secondary endpoints included: analgesic drug consumption, length of hospital stay, delay to return to normal activity and patient satisfaction. Results: There was no difference concerning operative time (36.3 ± 14.0 vs 39.6 ± 7.2 minutes) and early (one-week) complications, although there was a non significant reduced incidence of hematoma and ecchymosis (0/54 versus 4/54) for the cold compress group. Analgesic drug consumption was significantly (p = 0.01) reduced. During the day of surgery and the first postoperative day, the visual analogue scale was significantly lower after cooling. There was a non-significant reduction in length of hospital stay (150 ± 37 versus 210 ± 47 min), and time to return to normal activity was shorter in the cold compress group. Conclusion: For open inguinal hernia repair, immediate pre- and post operative surgical site cooling, targeting a controlled temperature between 12?C and 15?C significantly reduced postoperative pain, analgesic drug consumption and resulted in improved immediate outcomes. This technique is safe, simple, easy to use, inexpensive and well tolerated by the patient.

Single Incision Laparoscopic Transabdominal Preperitoneal Repair for Strangulated Groin Hernia

Introduction: Single incision laparoscopic surgery (SILS) has become more popular for various surgical procedures including hernia surgery. Initial results of SILS in elective hernia repair were comparable to those of conventional laparoscopic approaches. However the use of SILS in emergency case has not been widely reported. This study aimed to evaluate the feasibility of the use of single incision laparoscopic transabdominal preperitoneal (TAPP) repair for patients presenting with strangulated groin hernia. Method: Emergency single incision laparoscopic TAPP repair were performed in our unit from June 2011 onwards for selected patients. Retrospectively data including the patient demographics, operative time, type of hernia, hospital stay, complications and recurrence rate were collected and analyzed. Result: There were a total of five patients in this series from June 2011 to June 2012. The median age was 62 years old with a male to female ratio of 4:1. Four patients had unilateral hernia (one femoral and three inguinal hernias) and one had bilateral hernia (unilaterally strangulated femoral hernia and bilaterally reducible indirect inguinal hernia). The median operative time was 75 minutes for patients with unilateral repair. None of the patients required bowel resection. The conversion rate to either conventional laparoscopic or open repair was zero. The median hospital stay was 2 days. No major complication or recurrence was detected. Conclusion: This series showed that single port laparoscopic TAPP repair for strangulated groin hernia is a feasible option with no major complication reported.

Cardiovascular Complications of Large Hiatal Hernias: Expanding the Indications for Robotic Surgical Anatomic and Physiologic Repair: A Review

Background: Historically, the pathophysiology of Hiatal Hernias (HH) has not been fully understood. As a result, the surgical therapy of HH has focused primarily on gastrointestinal symptoms and Gastroesophageal Reflux (GERD). This treatment strategy has been associated with poor relief of symptoms and poor long-term outcomes. In fact, until recently, most patients with HH have been watched and referred for surgery as a last resort. Recent experience has shown that a large (giant) Hiatal Hernia (GHH) is a common problem known to impact adjacent organs such as the hearts and lungs. Those referred for surgical repair often complain of dyspnea, which is erroneously attributed to pulmonary compression or aspiration, but has been shown to be from tamponade caused from compression of the heart by herniated abdominal contents. This article reviews the present understanding of GHH, the cardiac complications which result from GHH, and the most advanced robotic minimally invasive surgical approach to the anatomic and physiologic repair of GHH. Methods: In a prospective cohort study, we evaluated patients undergoing RRHH with at least a 2-year follow-up. All patients undergoing elective (RRHH) were identified preoperatively and enrolled prospectively in this study. Preoperative characteristics, medical comorbidities, and clinical information were all recorded prospectively and recorded into a secure surgical outcomes database. All patients received the previously validated Gastroesophageal Reflux Disease-Health-Related Quality of Life (GERD-HRQL) questionnaire preoperatively and at postoperative time points of 1 month, 1 year, and 2 years. Patients routinely had a barium swallow postoperatively before discharge but did not undergo a barium swallow, an endoscopy, or a CT scan study at the 1-month time point unless indicated by symptoms. At 6 months, 1 year, and yearly intervals thereafter, all patients received an endoscopy study to ascertain the presence of a recurrence, regardless of symptoms. Recurrence was defined as over 2 cm or 10% of the stomach above the diaphragm detected by CT, esophagogram or endoscopy. In addition, an extensive search was conducted using Pub Med in order to extract references to the cardiovascular complications of HH. Results: 423 patients underwent RRHH. With a long-term follow-up, there was a significant decrease in the Median Symptom Severity Score from 42.0 preoperatively, to 3.0 postoperatively. Recurrence was seen in 5 patients (5/423) for a recurrence rate of 1.1%. Conclusion: This experience has been the basis of two important realizations: 1) all patients with GHH have at least some degrees of clinically relevant compression of the inferior vena cava and the left atrium which causes tamponade and cardiogenic dyspnea which completely resolves after successful surgical repair;and 2) primary care providers and gastroenterologists who usually treat patients for GHH repair rarely recognize cardiac compression and tamponade as the cause of the shortness of breath and gradual increase in dyspnea on exertion and progressive fatigability in these patients. This article reviews the present understanding of GHH, the cardiac complications which result from GHH and the most advanced robotic minimally invasive surgical approach to the anatomic and physiologic repair of GHH.

腹腔镜联合开腹补片修补术对巨大切口疝及肠粘连紧密腹壁切口疝患者的临床研究

目的以巨大切口疝、肠粘连紧密腹壁切口疝患者为试验对象,评估腹腔镜联合开腹补片修补术的临床应用价值。方法确定研究时间为2022年1月至2024年1月,入组对象均选择本院确诊为巨大切口疝及肠粘连紧密腹壁切口疝的患者,抽检入组样本共计60例,根据病情、手术指征进行手术方案选择,将入试者划分为两组,即对照组、观察组,对照组采取开腹补片修补术治疗,观察组患者则应用腹腔镜联合开腹补片修补术,对比临床治疗效果。结果观察组患者围手术期指标,术后并发症发生率,血清InS、GH及T-AOC、β-EP水平,炎症因子水平均优于对照组(P<0.05)。结论巨大切口疝及肠粘连紧密腹壁切口疝患者治疗期间腹腔镜联合开腹补片修补术具有较高安全性和有效性,可缩短患者疼痛持续时间,减少出血量。

经腹腹膜前疝修补术与开放手术在腹股沟直疝治疗中的疗效比较研究

目的本研究旨在比较腹腔镜经腹腹膜前疝修补术(TAPP)与开放手术在治疗腹股沟直疝中的疗效。方法本项回顾性研究纳入了2019年3月至2024年5月期间在信阳市第三人民医院接受治疗的91例腹股沟直疝患者,根据手术方式将其分为两组。观察组46例,采用腹腔镜TAPP技术进行修补,对照组45例,采用传统开放手术进行修补。比较两组患者的手术时间、术中出血量、术后首次排气与下床时间、住院时间、术后疼痛评分、并发症发生率等指标。结果观察组手术用时、手术失血量、首次排气时间、首次下床时间以及住院时间方面均显著低于对照组,差异有统计学意义(P<0.05)。术后24h、48h和72h,两组患者VAS评分均较术前降低,且观察组各时段VAS评分均低于对照组,差异有统计学意义(P<0.05)。术后48h,两组患者hs-CRP、IL-6和IL-4水平均较术前降低,且观察组低于对照组,差异均有统计学意义(P<0.05)。观察组并发症发生率(8.70%)低于对照组(40.00%),差异有统计学意义(P<0.05)。结论腹腔镜经腹腹膜前疝修补术在治疗腹股沟直疝方面表现出显著的临床效果。该方法能够有效减轻患者术后疼痛,缩短手术时间,加速康复过程,具有临床应用价值。

腹腔镜全腹膜外腹股沟疝修补术在治疗急性绞窄性腹股沟疝中的应用分析

目的:探讨腹腔镜全腹膜外腹股沟疝修补术(Total extraperitoneal repair inguinal hernia repair,TEP)在急性绞窄性腹股沟疝应用价值分析。方法:选取2018年1月至2023年12月于我院诊断为急性绞窄性腹股沟疝的58例患者作为研究对象,随机分为腹腔镜组和开腹组,各29例。比较两组患者围手术期实验室检查指标、手术时间、术后排气时间、术后并发症发生率、术后引流管拔除时间、住院时间等指标。结果:术后第3 d,两组白细胞(White blood cells,WBC)、尿素氮(Urea nitrogen,BUN)、肌酐(Creatinine,Cr)、C反应蛋白(C-reactive protein,CRP)均明显下降,且腹腔镜组明显低于开腹组(P<0.05);白蛋白(Albumin,ALB)水平均明显升高,且腹腔镜组明显高于开腹组(P<0.05);腹腔镜组在术中出血量、术后排气时间、术后进食时间、引流管拔除时间、住院时间均明显少于开腹组(P<0.05);两组手术时间无明显差异(P>0.05);腹腔镜组的肺部感染、伤口感染的发生率明显低于开腹组(P<0.05)。结论:腹腔镜全腹膜外腹股沟疝修补术对治疗急诊绞窄性腹股沟疝是安全的、可行的,较开放手术有一定的优势。

全腹膜外疝修补术及微创无张力疝修补术治疗成人腹股沟疝的效果

目的:观察全腹膜外疝修补术(total extraperitoneal herniorrhaphy,TEP)及微创无张力疝修补术治疗成人腹股沟疝的效果。方法:选取2020年1月—2022年12月宜兴市人民医院普外科收治的280例腹股沟疝患者作为研究对象。根据随机数表法将其分为观察组和对照组,各140例。对照组实施微创无张力疝修补术(Lichtenstein)治疗,观察组实施TEP治疗。比较两组围手术期指标,入院当日、出院前1 d胃肠功能、应激指标、疼痛程度、生活质量。结果:观察组首次肛门排气时间、下床时间均早于对照组,住院时间短于对照组,差异有统计学意义(P<0.05)。出院前1 d,两组胃动素(motilin,MTL)水平升高,胃蛋白酶原(pepsinogen,PG)水平降低,观察组MTL水平高于对照组,PG水平低于对照组,差异有统计学意义(P<0.05)。出院前1 d,两组肾上腺皮质激素(adrenal cortex hormone,ACH)、去甲肾上腺素(norepinephrine,NE)、皮质醇(cortisol,Cor)水平均降低,观察组ACH、NE、Cor水平均低于对照组,差异有统计学意义(P<0.05)。出院前1 d,两组面部表情、肢体活动、治疗适应性评分均降低,观察组面部表情、肢体活动、治疗适应性评分均低于对照组,差异有统计学意义(P<0.05)。出院前1 d,两组生理功能、心理功能、社会功能评分均升高,观察组生理功能、心理功能、社会功能评分均高于对照组,差异有统计学意义(P<0.05)。结论:TEP治疗能够有效降低成人腹股沟疝患者激素水平,改善胃肠功能。

格隆溴铵对老年患者腹腔镜腹股沟疝修补术的术后认知功能障碍的影响

目的探讨格隆溴铵术前用药对老年患者腹腔镜腹股沟疝修补术的术后认知功能障碍(POCD)的影响。方法选取择期行喉罩全身麻醉腹腔镜腹股沟疝修补手术的老年患者74例,随机分为对照组(C组,25例)、低剂量格隆溴铵组(0.2 mg,L组,24例)和中剂量格隆溴铵组(0.4 mg,M组,25例)。于术前1 d和手术后3 d分别采集患者血液样本,采用ELISA法检测血清炎症因子[白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)]和脑功能相关因子[5-羟色胺(5-HT)和脑源性神经营养因子(BDNF)]含量,分析术前和术后血清5-HT、炎症因子和BDNF的变化。使用蒙特利尔认知评估量表(MoCA)对术前1 d和手术后3 d患者的认知功能进行评估,并分析手术前后患者认知功能的变化。记录置入喉罩前或拔除喉罩后气道分泌物评分、心律失常、口干和排尿困难的发生情况。结果3组患者POCD发生率比较,差异无统计学意义(P>0.05);术后3 d,L组血清5-HT和BDNF水平明显高于C组,L组血清BDNF水平明显高于M组,差异均有统计学意义(P<0.05);术后3 d,C组血清IL-1β、IL-6和TNF-α水平较术前1 d明显升高,差异均有统计学意义(P<0.05),M组血清IL-6和TNF-α水平较术前1 d明显升高,差异均有统计学意义(P<0.05),L组血清IL-1β、IL-6和TNF-α水平与术前1 d比较,差异均无统计学意义(P>0.05),3组患者术后3 d血清IL-1β、IL-6和TNF-α水平组间比较,差异均无统计学意义(P>0.05);与C组比较,L组和M组术后气道分泌物明显减少,差异均有统计学意义(P<0.05),但L组与M组比较,差异无统计学意义(P>0.05);M组不良反应发生率(口干和排尿困难)较L组和C组明显增加,差异均有统计学意义(P<0.05)。结论低剂量(0.2 mg)格隆溴铵更适合作为老年患者腹腔镜腹股沟疝修补术的术前用药,增加剂量可能增加POCD和不良反应的风险。

经腹腔腹膜前腹腔镜疝修补手术对腹股沟疝患者血清炎性因子及术后疼痛的影响

目的探讨经腹腔腹膜前腹腔镜疝修补术(TAPP)在腹股沟疝(IH)中的应用效果.方法回顾性分析2021年6月—2023年6月我院收治的102例IH患者的临床资料,将行开放式无张力疝修补术的51例设为对照组,将行TAPP术的51例设为观察组.比较两组手术情况、血清炎性因子、术后疼痛、并发症发生情况.结果观察组手术时间为(61.85±6.87)min,长于对照组的(50.04±6.43)min,术中出血量为(10.89±1.45)mL,少于对照组的(15.53±1.83)mL,肛门排气、住院时间分别为(16.25±1.33)h、(3.91±0.43)d,均短于对照组的(18.87±1.47)h、(4.82±0.54)d,组间差异有统计学意义(P<0.05).术后,观察组超敏C反应蛋白、降钙素原水平分别为(10.52±1.39)mg/L、(0.69±0.12)ng/mL,均低于对照组的(13.87±1.45)mg/L、(0.78±0.14)ng/mL,组间差异有统计学意义(P<0.05).术后6、24、48 h,观察组疼痛视觉模拟评分分别为(4.72±0.58)分、(2.91±0.35)分、(1.35±0.21)分,均低于对照组的(5.87±1.04)分、(3.62±0.43)分、(1.82±0.24)分,组间差异有统计学意义(P<0.05).两组并发症发生率比较,差异无统计学意义(P>0.05).结论TAPP术治疗IH价值更高,可减轻手术创伤,降低炎症水平,值得广泛应用.

中国疝修补技术30年的演变和进展

本文概述疝病的基本概念及其历史沿革。“无张力修补”概念的引入使得疝外科有了里程碑式飞跃,“腹壁功能”概念的建立则推动了疝外科的发展。介绍疝修补技术在我国的引入和推广,重点讨论中国疝外科修补技术的发展阶段,包括开放手术、腹腔镜手术和机器人手术,以及微创技术在疝修补中的应用和发展。指出应按腹壁疝的分型来选择手术方式以及腹壁重建的3R[修补(repair),组织结构重建(reconstruction),结构重塑和功能修复(restoration)]原则。还探讨材料科学的进展和日间手术模式的推广。

三种不同腹股沟疝手术修补方案的临床有效性及安全性分析

目的 比较平片无张力疝修补术(Lichtenstein)、疝环充填式疝修补术(Rutkow)、腹膜前修补术(Kugel)三种修补方案治疗腹股沟疝的疗效及安全性。方法 60例成人腹股沟疝患者,根据修补方案的不同分为Lichtenstein组、Rutkow组、Kugel组,各20例。比较三组临床指标(手术时间、术后下床时间、住院时间)、术后早期并发症发生情况、术后不同时间疼痛程度及随访2年的术后复发率、异物感。结果 Lichtenstein组、Rutkow组、Kugel组手术时间分别为(65.2±10.3)、(58.6±9.5)、(72.1±11.2)min,术后下床时间分别为(12.8±3.1)、(10.4±2.6)、(14.2±3.5)h,住院时间分别为(5.6±1.2)、(4.9±1.0)、(6.2±1.4)d,三组比较有显著差异(P<0.05)。Kugel组术后早期并发症发生率5.00%略低于Lichtenstein组的10.00%和Rutkow组的10.00%,但并无显著差异(P>0.05)。术后1 d, Lichtenstein组、Rutkow组、Kugel组视觉模拟评分法(VAS)评分分别为(4.13±1.02)、(4.22±1.33)、(3.91±1.40)分,比较无显著差异(P>0.05)。术后1个月, Lichtenstein组、Kugel组VAS评分分别为(2.31±0.41)、(2.26±0.57)分,均低于Rutkow组的(3.16±0.92)分;术后6个月, Lichtenstein组、Kugel组VAS评分分别为(1.02±0.97)、(0.97±0.82)分,均低于Rutkow组的(1.91±1.55)分,有显著差异(P<0.05)。在术后2年的随访中,三组复发率比较,无显著差异(P>0.05);但Rutkow组的异物感占比60.00%明显高于Lichtenstein组的5.0%和Kugel组的10.0%,有显著差异(P<0.05)。结论 Lichtenstein、Rutkow、Kugel治疗腹股沟疝的疗效及并发症几乎接近,宜根据不同病例采用不同方案。

腹腔镜下疝修补术对腹股沟疝患儿的影响

目的:探讨腹腔镜下疝修补术对腹股沟疝患儿的影响。方法:选取2021年2月—2023年7月黔西市人民医院收治的600例腹股沟疝患儿。根据随机数表法将其分为观察组和对照组,各300例。对照组给予传统开腹疝修补术,观察组给予腹腔镜下疝修补术。比较两组围手术期指标,术前及术后24 h炎症因子、生理应激指标及并发症。结果:观察组手术时间、下床活动时间、住院时间均短于对照组,术后24 h视觉模拟评分法(VAS)评分低于对照组,差异有统计学意义(P<0.05)。术后24 h,观察组白细胞介素-6(IL-6)、C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)水平均低于对照组,差异有统计学意义(P<0.05)。术后24 h,观察组促肾上腺皮质激素(ACTH)、皮质醇(Cor)、去甲肾上腺素(NE)、舒张压(DBP)、收缩压(SBP)水平均低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:腹腔镜下疝修补术用于腹股沟疝患儿中效果显著,手术时间、术后住院时间短,且对机体创伤更小、疼痛更轻,且并发症少。

腹膜前腹腔镜疝修补术治疗腹股沟疝的临床效果及对微环境指标的影响

目的:探究腹膜前腹腔镜疝修补术(TAPP)治疗腹股沟疝的临床效果及对微环境指标的影响。方法:选取2019年3月—2023年3月南通市老年康复医院收治的80例腹股沟疝患者。根据随机数表法将其分为对照组及观察组,各40例。对照组给予常规疝修补术,观察组给予TAPP。比较两组围手术期指标,术后1 d、3 d、7 d疼痛程度,术后1 d氧化应激指标、微环境指标,并发症。结果:观察组术中出血量少于对照组,住院时间短于对照组,术后活动时间早于对照组,差异有统计学意义(P<0.05)。术后1 d、3 d、7 d,观察组视觉模拟评分法(VAS)评分低于对照组,差异有统计学意义(P<0.05)。术后1 d,观察组β-内啡肽(β-EP)水平低于对照组、总抗氧化能力(T-AOC)、胰岛素(InS)水平均高于对照组,差异有统计学意义(P<0.05)。术后1 d,观察组基质金属蛋白酶-2(MMP-2)、基质金属蛋白酶-9(MMP-9)、基质金属蛋白酶组织抑制剂-1(TIMP-1)、基质金属蛋白酶组织抑制剂-2(TIMP-2)水平均低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:对腹股沟疝患者实施TAPP治疗,可减轻疼痛,对机体微环境影响较小,促进患者预后恢复。

腹腔镜与改良Kugel手术在成人腹股沟疝修补术中疗效比较的Meta分析

目的系统评价腹腔镜腹股沟疝修补术(LIHR)与改良Kugel手术用于腹股沟疝治疗方面的差异。方法通过检索PubMed、Cochrane Library、Embase、Web Science、CNKI、VIP、CBM和Wanfang数据库,收集LIHR与改良Kugel手术治疗腹股沟疝的中英文对照研究,查找时间为建库至2022年9月。2名独立研究者对检索出的所有中英文文献进行文献筛选和纳入文献质量评估后,再采用RevMan 5.3进行Meta分析。结果最终共纳入12项研究,4197例患者,其中LIHR组2415例,改良Kugel手术组1782例。与改良Kugel手术组相比,LIHR组术中出血量少(P=0.0004),24 h VAS评分低(P=0.007),术后下床活动时间短(P=0.003),切口感染(P=0.0003)及慢性疼痛发生率低(P<0.00001),长期并发症少(P<0.0001);两组在手术时间、术后复发和短期并发症中差异无统计学意义(P>0.05)。结论LIHR是一种安全有效的手术方式,与改良Kugel手术相比更具临床优势。