Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biot...Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biotechnology and its applications in the field of neuropsychiatry.Available evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin deficit.In vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric diseases.Although the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic applications.However,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical applications.This review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.展开更多
The terahertz band lies between the microwave and infrared regions of the electromagnetic spectrum.This radiation has very low photon energy and thus it does not pose any ionization hazard for biological tissues.It is...The terahertz band lies between the microwave and infrared regions of the electromagnetic spectrum.This radiation has very low photon energy and thus it does not pose any ionization hazard for biological tissues.It is strongly attenuated by water and very sensitive to water content.Unique absorption spectra due to intermolecular vibrations in this region have been found in different biological materials.These unique features make tera-hertz imaging very attractive for medical applications in order to provide complimentary information to existing imaging techniques.There has been an increasing interest in terahertz imaging and spectroscopy of biologically related applications within the last few years and more and more terahertz spectra are being reported.This paper introduces terahertz technology and provides a short review of recent advances in terahertz imaging and spectroscopy techniques,and a number of applications such as molecular spectroscopy,tissue characterization and skin imaging are discussed.展开更多
The water content in vegetative leaves is an important indicator to plant science.It reveals the physiological status of plants and provides valuable information in irrigation management.Terahertz(THz)as a state-of-th...The water content in vegetative leaves is an important indicator to plant science.It reveals the physiological status of plants and provides valuable information in irrigation management.Terahertz(THz)as a state-of-the-art technology shows great potential in measuring and monitoring the water status in plant leaves.This paper reviewed the theoretical models for calculating water content in the plant leaves,the methods for eliminating the scattering loss caused by the surface roughness of leaf,the applications of THz spectroscopy and THz imaging for monitoring leaf water content and describing leaf water distribution.The survey of the researches presents the considerable advantages of this emerging and promising THz technology in agriculture.展开更多
In order to improve the imaging quality of terahertz(THz) spectroscopy, Terahertz Composite Imaging Method(TCIM) is proposed. The traditional methods of improving THz spectroscopy image quality are mainly from the asp...In order to improve the imaging quality of terahertz(THz) spectroscopy, Terahertz Composite Imaging Method(TCIM) is proposed. The traditional methods of improving THz spectroscopy image quality are mainly from the aspects of de-noising and image enhancement. TCIM breaks through this limitation. A set of images, reconstructed in a single data collection, can be utilized to construct two kinds of composite images. One algorithm, called Function Superposition Imaging Algorithm(FSIA), is to construct a new gray image utilizing multiple gray images through a certain function. The features of the Region Of Interest(ROI) are more obvious after operating, and it has capability of merging ROIs in multiple images. The other, called Multi-characteristics Pseudo-color Imaging Algorithm(Mc Pc IA), is to construct a pseudo-color image by combining multiple reconstructed gray images in a single data collection. The features of ROI are enhanced by color differences. Two algorithms can not only improve the contrast of ROIs, but also increase the amount of information resulting in analysis convenience. The experimental results show that TCIM is a simple and effective tool for THz spectroscopy image analysis.展开更多
A review on Terahertz end-to-end systems with an emphasis on integrated approaches is presented.Four major catalogs of THz integrated systems,including THz communication systems,THz imaging systems,THz radars,and THz ...A review on Terahertz end-to-end systems with an emphasis on integrated approaches is presented.Four major catalogs of THz integrated systems,including THz communication systems,THz imaging systems,THz radars,and THz spectroscopy systems,are reviewed in this article.The performance of integrated systems is compared with non-integrated solutions,followed by a discussion on the trend in future research avenues and applications.展开更多
The analysis on the thickness of polyamide plate using Terahertz Time Domain System(THz-TDS)in reflection mode is carried out.The refractive index,one of the optical parameters in terahertz band,is solved through the ...The analysis on the thickness of polyamide plate using Terahertz Time Domain System(THz-TDS)in reflection mode is carried out.The refractive index,one of the optical parameters in terahertz band,is solved through the mathematics model,and its value is 1.88.A kind of polyamide plate sample with four kinds of thickness is designed and the ability of THz-based method to detect defects or foreign bodies in fiber glass is verified by attaching metal plates to the back of fiberglass.By the comparison of traditional method and THz method,the terahertz method has a measurement error between 2.5%and 10%.As the thickness increases,the error tends to increase.The reason about the deviations is analyzed,as well as the systematic factors affecting the thickness measurement accuracy,in order to improve the accuracy of THz thickness measurement system and provide theoretical basis for designing terahertz thickness measurement system in the future.展开更多
The work presented in this paper was performed at the Oriental Institute at the University of Chicago, on objects from their permanent collection： an ancient Egyptian bird mummy and three ancient Sumerian corroded co...The work presented in this paper was performed at the Oriental Institute at the University of Chicago, on objects from their permanent collection： an ancient Egyptian bird mummy and three ancient Sumerian corroded copper-alloy objects. We used a portable, fibercoupled terahertz （THz） time-domain spectroscopic ima- ging system, which allowed us to measure specimens in both transmission and reflection geometry, and present time- and frequency-based image modes. The results confirm earlier evidence that THz imaging can provide complementary information to that obtainable from X-ray computed tomography （XRCT） scans of mummies, giving better visualisation of low density regions. In addition, we demonstrated that THz imaging can distinguish mineralized layers in metal artifacts.展开更多
基金supported by grants from the National Key R&D Program of China,No.2017YFC0909200(to DC)the National Natural Science Foundation of China,No.62075225(to HZ)+1 种基金Zhejiang Provincial Medical Health Science and Technology Project,No.2023XY053(to ZP)Zhejiang Provincial Traditional Chinese Medical Science and Technology Project,No.2023ZL703(to ZP).
文摘Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biotechnology and its applications in the field of neuropsychiatry.Available evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin deficit.In vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric diseases.Although the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic applications.However,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical applications.This review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.
基金Supported by in part for this work from the Research Grants Council of the Hong Kong Government and the Shun Hing Institute of Advanced Engineering, Hong Kong
文摘The terahertz band lies between the microwave and infrared regions of the electromagnetic spectrum.This radiation has very low photon energy and thus it does not pose any ionization hazard for biological tissues.It is strongly attenuated by water and very sensitive to water content.Unique absorption spectra due to intermolecular vibrations in this region have been found in different biological materials.These unique features make tera-hertz imaging very attractive for medical applications in order to provide complimentary information to existing imaging techniques.There has been an increasing interest in terahertz imaging and spectroscopy of biologically related applications within the last few years and more and more terahertz spectra are being reported.This paper introduces terahertz technology and provides a short review of recent advances in terahertz imaging and spectroscopy techniques,and a number of applications such as molecular spectroscopy,tissue characterization and skin imaging are discussed.
基金This work was supported by the National Key Point Research and Invention Program of the Thirteenth(2016YFD0700304)the National Key Research&Development program of China(2016YFD0300606 and 2017YFD0700501).
文摘The water content in vegetative leaves is an important indicator to plant science.It reveals the physiological status of plants and provides valuable information in irrigation management.Terahertz(THz)as a state-of-the-art technology shows great potential in measuring and monitoring the water status in plant leaves.This paper reviewed the theoretical models for calculating water content in the plant leaves,the methods for eliminating the scattering loss caused by the surface roughness of leaf,the applications of THz spectroscopy and THz imaging for monitoring leaf water content and describing leaf water distribution.The survey of the researches presents the considerable advantages of this emerging and promising THz technology in agriculture.
基金National defense technical basic research project,Terahertz Detection Technology and Application Research on Ceramic Matrix Composites(JSZL2015411C002).
文摘In order to improve the imaging quality of terahertz(THz) spectroscopy, Terahertz Composite Imaging Method(TCIM) is proposed. The traditional methods of improving THz spectroscopy image quality are mainly from the aspects of de-noising and image enhancement. TCIM breaks through this limitation. A set of images, reconstructed in a single data collection, can be utilized to construct two kinds of composite images. One algorithm, called Function Superposition Imaging Algorithm(FSIA), is to construct a new gray image utilizing multiple gray images through a certain function. The features of the Region Of Interest(ROI) are more obvious after operating, and it has capability of merging ROIs in multiple images. The other, called Multi-characteristics Pseudo-color Imaging Algorithm(Mc Pc IA), is to construct a pseudo-color image by combining multiple reconstructed gray images in a single data collection. The features of ROI are enhanced by color differences. Two algorithms can not only improve the contrast of ROIs, but also increase the amount of information resulting in analysis convenience. The experimental results show that TCIM is a simple and effective tool for THz spectroscopy image analysis.
文摘A review on Terahertz end-to-end systems with an emphasis on integrated approaches is presented.Four major catalogs of THz integrated systems,including THz communication systems,THz imaging systems,THz radars,and THz spectroscopy systems,are reviewed in this article.The performance of integrated systems is compared with non-integrated solutions,followed by a discussion on the trend in future research avenues and applications.
文摘The analysis on the thickness of polyamide plate using Terahertz Time Domain System(THz-TDS)in reflection mode is carried out.The refractive index,one of the optical parameters in terahertz band,is solved through the mathematics model,and its value is 1.88.A kind of polyamide plate sample with four kinds of thickness is designed and the ability of THz-based method to detect defects or foreign bodies in fiber glass is verified by attaching metal plates to the back of fiberglass.By the comparison of traditional method and THz method,the terahertz method has a measurement error between 2.5%and 10%.As the thickness increases,the error tends to increase.The reason about the deviations is analyzed,as well as the systematic factors affecting the thickness measurement accuracy,in order to improve the accuracy of THz thickness measurement system and provide theoretical basis for designing terahertz thickness measurement system in the future.
文摘The work presented in this paper was performed at the Oriental Institute at the University of Chicago, on objects from their permanent collection： an ancient Egyptian bird mummy and three ancient Sumerian corroded copper-alloy objects. We used a portable, fibercoupled terahertz （THz） time-domain spectroscopic ima- ging system, which allowed us to measure specimens in both transmission and reflection geometry, and present time- and frequency-based image modes. The results confirm earlier evidence that THz imaging can provide complementary information to that obtainable from X-ray computed tomography （XRCT） scans of mummies, giving better visualisation of low density regions. In addition, we demonstrated that THz imaging can distinguish mineralized layers in metal artifacts.
