Background: A subset of cancer is particularly vulnerable to hydration prior to chemotherapy protocols;however, real-world outcomes-based data on pre-hydration elements of patients with tumor is sparse. Case Presentat...Background: A subset of cancer is particularly vulnerable to hydration prior to chemotherapy protocols;however, real-world outcomes-based data on pre-hydration elements of patients with tumor is sparse. Case Presentations: This retrospective case series describes a cohort of adult patients with terminal stage cancer who were seen between July 1, 2023, and September 25, 2023 and underwent various chemotherapy protocols, which, to our knowledge, represents comprehensive analysis of this patient population. We performed a retrospective search of patients identifying 50 cases of the chemotherapies of patients with cancer and extracted the clinical data via individual chart reviews. At the time of diagnosis, 24 patients were prehydrated with NaCl with KCl prior to the chemotherapy against the tumor, and 26 patients were taking normal saline only before undergoing cancer-specific treatment. Hydration and, prior chemotherapeutic agents use were the most common predepositse. Carcinomatosis peritoneii were the most common signs of the terminal stage of cancer within patients. Twenty-four patients were admitted to the hospital and two received NaCl with KCl hydaration prior to the platinum based chemotherapeutic agent treatment. Twenty-six patients received only normal saline hydration. Conclusion: Our data suggest that NaCl with KCl prehydaration results in better prognosis, including reduced tumor burden or decreased lymph node invasion, when compared to other vulnerable patients populations that receive only normal saline hydration. The graphene exfoliation effect of NaCl with KCl may have contributed to these results.展开更多
Objective: To evaluate the effect of Baoyuan Qiangshen Tablet No. I (BYQS), a Chinese herbal medicine for reinforcing Kidney, activating circulation and eliminating evil Turbid factors, in prolongating interval of hem...Objective: To evaluate the effect of Baoyuan Qiangshen Tablet No. I (BYQS), a Chinese herbal medicine for reinforcing Kidney, activating circulation and eliminating evil Turbid factors, in prolongating interval of hemodialysis in patients of terminal stage of renal disease (TSRD). Methods : Twenty cases of TSRD were treated with BYQS combined with hemodialysis once every 5 days and the effect was observed and compared with control group treated with routine hemodialysis once every 3 days. Results : The increasing levels of serum creatinine, and blood urea nitrogen of BYQS group at dialysis interval were all lower than those of the control group (P< 0. 01 ). After 3 months' treatment, serum creatinine, blood urea nitrogen of BYQS group were lower than those before treatment, plasma albumin, lipoprotein, urine level of prostaglandin and anemia were all improved to various extent, but the creatinine clearance rate was unchanged. Conclusions : BYQS could prolong the interval and reduce the times of dialysis by way of regulating the lipid metabolic disorder, improving pathological change of kidney and protecting function of residual kidney unit. BYQS combined with hemodialysis is a good way of integrated traditional Chinese and Western medicine in treating TSRD.展开更多
文摘Background: A subset of cancer is particularly vulnerable to hydration prior to chemotherapy protocols;however, real-world outcomes-based data on pre-hydration elements of patients with tumor is sparse. Case Presentations: This retrospective case series describes a cohort of adult patients with terminal stage cancer who were seen between July 1, 2023, and September 25, 2023 and underwent various chemotherapy protocols, which, to our knowledge, represents comprehensive analysis of this patient population. We performed a retrospective search of patients identifying 50 cases of the chemotherapies of patients with cancer and extracted the clinical data via individual chart reviews. At the time of diagnosis, 24 patients were prehydrated with NaCl with KCl prior to the chemotherapy against the tumor, and 26 patients were taking normal saline only before undergoing cancer-specific treatment. Hydration and, prior chemotherapeutic agents use were the most common predepositse. Carcinomatosis peritoneii were the most common signs of the terminal stage of cancer within patients. Twenty-four patients were admitted to the hospital and two received NaCl with KCl hydaration prior to the platinum based chemotherapeutic agent treatment. Twenty-six patients received only normal saline hydration. Conclusion: Our data suggest that NaCl with KCl prehydaration results in better prognosis, including reduced tumor burden or decreased lymph node invasion, when compared to other vulnerable patients populations that receive only normal saline hydration. The graphene exfoliation effect of NaCl with KCl may have contributed to these results.
文摘Objective: To evaluate the effect of Baoyuan Qiangshen Tablet No. I (BYQS), a Chinese herbal medicine for reinforcing Kidney, activating circulation and eliminating evil Turbid factors, in prolongating interval of hemodialysis in patients of terminal stage of renal disease (TSRD). Methods : Twenty cases of TSRD were treated with BYQS combined with hemodialysis once every 5 days and the effect was observed and compared with control group treated with routine hemodialysis once every 3 days. Results : The increasing levels of serum creatinine, and blood urea nitrogen of BYQS group at dialysis interval were all lower than those of the control group (P< 0. 01 ). After 3 months' treatment, serum creatinine, blood urea nitrogen of BYQS group were lower than those before treatment, plasma albumin, lipoprotein, urine level of prostaglandin and anemia were all improved to various extent, but the creatinine clearance rate was unchanged. Conclusions : BYQS could prolong the interval and reduce the times of dialysis by way of regulating the lipid metabolic disorder, improving pathological change of kidney and protecting function of residual kidney unit. BYQS combined with hemodialysis is a good way of integrated traditional Chinese and Western medicine in treating TSRD.
