In this article,I trace my career from an early interest in language that eventually led me to engage in Chinese medical translation.Born in the United Kingdom in 1954,I gained a Bachelor of Arts degree in German and ...In this article,I trace my career from an early interest in language that eventually led me to engage in Chinese medical translation.Born in the United Kingdom in 1954,I gained a Bachelor of Arts degree in German and Spanish from the University of Heriot-Watt,Edinburgh.Subsequent study of Chinese took me to Taiwan,China,where I gained an interest in Chinese medicine and developed a coherent linguistic approach to Chinese medical term translation,which I and various colleagues have systematically applied in the translation and compilation of numerous works spanning modern texts,classics,dictionaries,and language-learning materials.Our translation approach,though conforming to principles universally recognized by translation theorists,has proven to be highly controversial,with opponents in both Western and Chinese circles.展开更多
A system for fully automatic selection of welding specifications in resistance welding equipment has been developed to address the problem of workers frequently choosing the wrong specifications during manual welding ...A system for fully automatic selection of welding specifications in resistance welding equipment has been developed to address the problem of workers frequently choosing the wrong specifications during manual welding of multiple parts on a single machine in automobile factories. The system incorporates an automatic recognition system for different workpiece materials using the added machine fixture,visual detection system for nuts and bolts,and secondary graphical confirmation to ensure the correctness of specification calling. This system achieves reliable,fully automatic selection of welding specifications in resistance welding equipment and has shown significant effects in improving welding quality for massproduced workpieces,while solving the problem of specification calling errors that can occur with traditional methods involving process charts and code adjustments. This system is particularly suitable for promoting applications in manual welding of multiple parts on a single machine in automobile factories,ensuring correct specification calling and welding quality.展开更多
In this review,we focus on providing basics and examples for each component of the protein therapeutic specifications to interested pharmacists and biopharmaceutical scientists with a goal to strengthen understanding ...In this review,we focus on providing basics and examples for each component of the protein therapeutic specifications to interested pharmacists and biopharmaceutical scientists with a goal to strengthen understanding in regulatory science and compliance.Pharmaceutical specifications comprise a list of important quality attributes for testing,references to use for test procedures,and appropriate acceptance criteria for the tests,and they are set up to ensure that when a drug product is administered to a patient,its intended therapeutic benefits and safety can be rendered appropriately.Conformance of drug substance or drug product to the specifications is achieved by testing an article according to the listed tests and analytical methods and obtaining test results that meet the acceptance criteria.Quality attributes are chosen to be tested based on their quality risk,and consideration should be given to the merit of the analytical methods which are associated with the acceptance criteria of the specifications.Acceptance criteria are set forth primarily based on efficacy and safety profiles,with an increasing attention noted for patient-centric specifications.Discussed in this work are related guidelines that support the biopharmaceutical specification setting,how to set the acceptance criteria,and examples of the quality attributes and the analytical methods from 60 articles and 23 pharmacopeial monographs.Outlooks are also explored on process analytical technologies and other orthogonal tools which are on-trend in biopharmaceutical characterization and quality control.展开更多
Context and Objective: Over the past few decades, terminologies developed for clinical descriptions have been increasingly used as key resources for knowledge management, data integration, and decision support to the ...Context and Objective: Over the past few decades, terminologies developed for clinical descriptions have been increasingly used as key resources for knowledge management, data integration, and decision support to the extent that today they have become essential in the biomedical and health field. Among these clinical terminologies, some may possess the characteristics of one or several types of representation. This is the case for the Systematized Nomenclature of Human and Veterinary Medicine—Clinical Terms (SNOMED CT), which is both a clinical medical terminology and a formal ontology based on the principles of semantic web. Methods: We present and discuss, on one hand, the compliance of SNOMED CT with the requirements of a reference clinical terminology and, on the other hand, the specifications of the features and constructions of descriptive of SNOMED CT. Results: We demonstrate the consistency of the reference clinical terminology SNOMED CT with the principles stated in James J. Cimino’s desiderata and we also show that SNOMED CT contains an ontology based on the EL profile of OWL2 with some simplifications. Conclusions: The duality of SNOMED CT shown is crucial for understanding the versatility, depth, and scope in the health field.展开更多
In this opinion paper, we introduce the expressions of dominant terminology and dominant term in the quantitative studies of science in analogy to the notion of dominant design in product development and innovation.
Big data on product sales are an emerging resource for supporting modular product design to meet diversified customers’requirements of product specification combinations.To better facilitate decision-making of modula...Big data on product sales are an emerging resource for supporting modular product design to meet diversified customers’requirements of product specification combinations.To better facilitate decision-making of modular product design,correlations among specifications and components originated from customers’conscious and subconscious preferences can be investigated by using big data on product sales.This study proposes a framework and the associated methods for supporting modular product design decisions based on correlation analysis of product specifications and components using big sales data.The correlations of the product specifications are determined by analyzing the collected product sales data.By building the relations between the product components and specifications,a matrix for measuring the correlation among product components is formed for component clustering.Six rules for supporting the decision making of modular product design are proposed based on the frequency analysis of the specification values per component cluster.A case study of electric vehicles illustrates the application of the proposed method.展开更多
We report a case of a 12-year-old female with closed and open comedo without inflammatory lesions at the first visit. She had been treated with topical adapalene once daily, and closed and open comedo subsided without...We report a case of a 12-year-old female with closed and open comedo without inflammatory lesions at the first visit. She had been treated with topical adapalene once daily, and closed and open comedo subsided without inflammatory lesions one month after the treatment without any side effects induced by adapalen. The recurrence of comedo had not been observed afterwards. In the Japanese Dermatological Association (JDA) guidelines for the treatment of acne vulgaris, comedonal phase has not been stated. Then we propose the tentative new terminology of a comedonal phase and emphasize its importance in the early initial treatment for comedo to prevent the development of the acute inflammatory phase such as red papules and pustules and formation of acne scars.展开更多
With the incessant propulsion of the Open Door Policy,which is related to the consolidation of international collaborative partnerships,an increasing number of Chinese companies are moving toward cooperating countries...With the incessant propulsion of the Open Door Policy,which is related to the consolidation of international collaborative partnerships,an increasing number of Chinese companies are moving toward cooperating countries to participate in infrastructure construction,employing a win-win strategy in favor of the people and governments of both countries.Among the cooperation domains,our country’s electrical companies have achieved a series of remarkable results in the international Engineering,Procurement,and Construction(EPC)project market with their outstanding business capabilities and technical advantages.Nevertheless,some shortcomings cannot be overlooked,the most notable of which appears to be the impediment associated with engineering translation,which has always been an obsession among translators of Chinese companies.Taking the transmission line project in the Republic of Madagascar as an example,an analysis of French-Chinese translation methods of electrical engineering terminology in the field of the transmission line is carried out.展开更多
文摘In this article,I trace my career from an early interest in language that eventually led me to engage in Chinese medical translation.Born in the United Kingdom in 1954,I gained a Bachelor of Arts degree in German and Spanish from the University of Heriot-Watt,Edinburgh.Subsequent study of Chinese took me to Taiwan,China,where I gained an interest in Chinese medicine and developed a coherent linguistic approach to Chinese medical term translation,which I and various colleagues have systematically applied in the translation and compilation of numerous works spanning modern texts,classics,dictionaries,and language-learning materials.Our translation approach,though conforming to principles universally recognized by translation theorists,has proven to be highly controversial,with opponents in both Western and Chinese circles.
文摘A system for fully automatic selection of welding specifications in resistance welding equipment has been developed to address the problem of workers frequently choosing the wrong specifications during manual welding of multiple parts on a single machine in automobile factories. The system incorporates an automatic recognition system for different workpiece materials using the added machine fixture,visual detection system for nuts and bolts,and secondary graphical confirmation to ensure the correctness of specification calling. This system achieves reliable,fully automatic selection of welding specifications in resistance welding equipment and has shown significant effects in improving welding quality for massproduced workpieces,while solving the problem of specification calling errors that can occur with traditional methods involving process charts and code adjustments. This system is particularly suitable for promoting applications in manual welding of multiple parts on a single machine in automobile factories,ensuring correct specification calling and welding quality.
基金supported by the Grant for Development of New Faculty Staff,Ratchadaphiseksomphot Endowment Fund,Chula-longkorn University,Thailand(Grant No.:DNS64_047_33_003_1 to Patanachai K.Limpikirati)Grant for Development of New Scholar,Office of the Permanent Secretary,Ministry of Higher Ed-ucation,Science,Research and Innovation,Thailand(Grant No.:RGNS64_012 to Patanachai K.Limpikirati).
文摘In this review,we focus on providing basics and examples for each component of the protein therapeutic specifications to interested pharmacists and biopharmaceutical scientists with a goal to strengthen understanding in regulatory science and compliance.Pharmaceutical specifications comprise a list of important quality attributes for testing,references to use for test procedures,and appropriate acceptance criteria for the tests,and they are set up to ensure that when a drug product is administered to a patient,its intended therapeutic benefits and safety can be rendered appropriately.Conformance of drug substance or drug product to the specifications is achieved by testing an article according to the listed tests and analytical methods and obtaining test results that meet the acceptance criteria.Quality attributes are chosen to be tested based on their quality risk,and consideration should be given to the merit of the analytical methods which are associated with the acceptance criteria of the specifications.Acceptance criteria are set forth primarily based on efficacy and safety profiles,with an increasing attention noted for patient-centric specifications.Discussed in this work are related guidelines that support the biopharmaceutical specification setting,how to set the acceptance criteria,and examples of the quality attributes and the analytical methods from 60 articles and 23 pharmacopeial monographs.Outlooks are also explored on process analytical technologies and other orthogonal tools which are on-trend in biopharmaceutical characterization and quality control.
文摘Context and Objective: Over the past few decades, terminologies developed for clinical descriptions have been increasingly used as key resources for knowledge management, data integration, and decision support to the extent that today they have become essential in the biomedical and health field. Among these clinical terminologies, some may possess the characteristics of one or several types of representation. This is the case for the Systematized Nomenclature of Human and Veterinary Medicine—Clinical Terms (SNOMED CT), which is both a clinical medical terminology and a formal ontology based on the principles of semantic web. Methods: We present and discuss, on one hand, the compliance of SNOMED CT with the requirements of a reference clinical terminology and, on the other hand, the specifications of the features and constructions of descriptive of SNOMED CT. Results: We demonstrate the consistency of the reference clinical terminology SNOMED CT with the principles stated in James J. Cimino’s desiderata and we also show that SNOMED CT contains an ontology based on the EL profile of OWL2 with some simplifications. Conclusions: The duality of SNOMED CT shown is crucial for understanding the versatility, depth, and scope in the health field.
文摘In this opinion paper, we introduce the expressions of dominant terminology and dominant term in the quantitative studies of science in analogy to the notion of dominant design in product development and innovation.
基金National Key R&D Program of China(Grant No.2018YFB1701701)Sailing Talent Program+1 种基金Guangdong Provincial Science and Technologies Program of China(Grant No.2017B090922008)Special Grand Grant from Tianjin City Government of China。
文摘Big data on product sales are an emerging resource for supporting modular product design to meet diversified customers’requirements of product specification combinations.To better facilitate decision-making of modular product design,correlations among specifications and components originated from customers’conscious and subconscious preferences can be investigated by using big data on product sales.This study proposes a framework and the associated methods for supporting modular product design decisions based on correlation analysis of product specifications and components using big sales data.The correlations of the product specifications are determined by analyzing the collected product sales data.By building the relations between the product components and specifications,a matrix for measuring the correlation among product components is formed for component clustering.Six rules for supporting the decision making of modular product design are proposed based on the frequency analysis of the specification values per component cluster.A case study of electric vehicles illustrates the application of the proposed method.
文摘We report a case of a 12-year-old female with closed and open comedo without inflammatory lesions at the first visit. She had been treated with topical adapalene once daily, and closed and open comedo subsided without inflammatory lesions one month after the treatment without any side effects induced by adapalen. The recurrence of comedo had not been observed afterwards. In the Japanese Dermatological Association (JDA) guidelines for the treatment of acne vulgaris, comedonal phase has not been stated. Then we propose the tentative new terminology of a comedonal phase and emphasize its importance in the early initial treatment for comedo to prevent the development of the acute inflammatory phase such as red papules and pustules and formation of acne scars.
文摘With the incessant propulsion of the Open Door Policy,which is related to the consolidation of international collaborative partnerships,an increasing number of Chinese companies are moving toward cooperating countries to participate in infrastructure construction,employing a win-win strategy in favor of the people and governments of both countries.Among the cooperation domains,our country’s electrical companies have achieved a series of remarkable results in the international Engineering,Procurement,and Construction(EPC)project market with their outstanding business capabilities and technical advantages.Nevertheless,some shortcomings cannot be overlooked,the most notable of which appears to be the impediment associated with engineering translation,which has always been an obsession among translators of Chinese companies.Taking the transmission line project in the Republic of Madagascar as an example,an analysis of French-Chinese translation methods of electrical engineering terminology in the field of the transmission line is carried out.