False Positive HIV “Combo” Screening Test in a Hemodialysis Patient in Saudi Arabia: A Case Report and Review of the Literature

Introduction: HIV screening tests are routinely conducted on dialysis patients as the constant exposure of their blood during the dialysis process makes them a reasonable risk for blood-borne infections. However, in low prevalence settings, where HIV rates are <0.1% of the population, false positive results are more likely. This results in apprehension in the dialysis unit as breaches in infectious disease protocols could be presumed. This is illustrated in the case report below. Case Summary: A 62-year-old male Saudi end-stage kidney disease patient secondary to DM nephropathy began dialysis a year before presentation in a hemodialysis center in Saudi Arabia. Routine screening tests done at the start of dialysis revealed negative Hepatitis C, HIV 1 and 2 screening but a positive Hepatitis B surface antigen screen. The patient went for holiday dialysis at another facility and had a routine fourth-generation HIV test done which was positive. A confirmatory HIV PCR test was negative. Conclusion: This case highlights the need for caution in interpreting highly sensitive and specific HIV screening tests in a low-prevalence setting. Routine screening beyond the national recommendation may not be necessary in low-prevalence areas.

CT colonography after incomplete colonoscopy in subjects with positive faecal occult blood test

AIM： To report our experience with computed tomography colonography （CTC） systematically performed in subjects with positive faecal occult blood test （FOBT） and an incomplete colonoscopy in the setting of a population-based screening for colorectal cancer （CRC）. METHODS： From April 2006 to April 2007, 43 290 individuals （age range 50-70） who adhered to the regional screening program for the prevention of CRC underwent immunochemical FOBT. FOBT was positive in 1882 subjects （4.3%）. 1463 （77.7%） of these subjects underwent colonoscopy, 903 performed in a single center. Of 903 colonoscopies 65 （7.2%） were incomplete. Forty-two of these subjects underwent CTC. CTC was performed with a 16-MDCT scanner after standard bowel prep （polyethyleneglycole） in both supine and prone position. Subjects whose CTC showed polyps or masses were referred to the endoscopist for repeat colonoscopy under sedation or underwent surgery. Perlesion and per-segment positive predictive values （PPV） were calculated. RESULTS： Twenty-one （50%） of 42 CTCs showed polyps or masses. Fifty-five of these subjects underwent a repeat colonoscopy, whereas 2 subjects underwent surgery for colonic masses of indeterminate nature. Four subjects refused further examinations. CTC correctly identified 2 colonic masses and 20 polyps. PPV for masses or polyps greater than 9 mm was of 87.5%. Per-lesion and per-segment PPV were, respectively, 83.3% and 83.3% for polyps greater or equal to 10 mm, and 77.8% and 85.7% for polyps of 6-9 mm. CONCLUSION： In the context of a screening program for CRC based on FOBT, CTC shows high per-segment and per-lesion PPV for colonic masses and polyps greater than 9 mm. Therefore, CTC has the potential to become a useful technique for evaluation of the non visualized part of the colon after incomplete colonoscopy.

Simple Statistical Tests Used in Positive Accounting Research： a Thing to be Noted

This paper is concerned with the right use of simple hypothesis tests in the area of positive accounting research. Both the usefulness and the limitations of the technique are dealt with in detail.

Factors to Give Full Play to the Positive Backwash Effect in the Language Testing

＂Backwash＂ has usually been described in terms of the effect of testing on language teaching and learning. ＂Backwash can be harmful or beneficial＂, as Arthur Hughes states. （Hughes： 1989） This paper set out to see how far this term can be applied to the ways in which both the students and teachers can benefit from language testing.

New System to Measure the Yaw and PitchAngles of Rocket in Launch Phase

Aim To describe a news system for measuring the and pitch angles of rocket during the launch phase Methods Optical system was to reflect the spot that represents the angular movement of rocket to the position sensitive detector that can convert analogue signal into digital one.Results Compared with conventional optical lever test system which had been applied to measure rocket attitude angle,the new system used the position sensitive detector to replace the screen and high-speed photographic instrumentation as grapher,which can avert photointerpretive data reduction and apply to field experiment more easily and pre- cisely .Conclusion Experimental results show that the test system can be used in measuring the yaw and pitch angles of rocket effectively.

Multiple Choice Items in Testing

Language testing is very important and necessary,and moreover as we all know,nowadays,in English language testing, the muhiple-choice item is most widely used and many users regard the multiple-choice item as the most flexible and probably the most effective of the objective item types.The multiple-choice item has its characteristics,advantages and disadvantages.We should bring out its strengths to make up for its weaknesses and use it appropriately.Although it has its limitations,it is suitable for large-scale tests and tests dealing with wide-range knowledge.We should correctly ap- ply testing principles and methods in order to make testing more effective and reliable.

Model-Based Embedded Compiled Software Fault Positioning

Software fault positioning is one of the most effective activities in program debugging. In this paper, we propose a model-based fault positioning method to detect the faults of embedded program without source code. The system takes the machine code of embedded software as input and translates the code into high-level language C with the software reverse engineering program. Then, the static analysis on the high-level program is taken to obtain a control flow graph（CFG）, which is denoted as a node-tree and each node is a basic block. According to the faults found by the field testing, we construct a fault model by extracting the features of the faulty code obtained by ranking the Ochiai coefficient of basic blocks. The model can be effectively used to locate the faults of the embedded program. Our method is evaluated on ST chips of the smart meter with the corresponding source code. The experiment shows that the proposed method has an effectiveness about 87% on the fault detection.

Quantities and function of NK cells in patients with positive BMMNC-Coombs test and cytopenia

Objective To test NK cell quantities and function in patients with positive BMMNC-Coombs test(CBCPC)and cytopenia and to explore how NK cell participate in the progress of this disease.Methods The percentage of CD3-CD56+NK cell in peripheral blood lymphocytes,the expression of activating receptor(NKG2D,NKp46,NKp44),inhibitory receptor(CD158a,CD158b),per-