Even if two implementations of a protocol pass the conformance testing,it cannot guarantee that they can interoperate properly;so direct testing of interoperation is considered indispensable.During the interoperabilit...Even if two implementations of a protocol pass the conformance testing,it cannot guarantee that they can interoperate properly;so direct testing of interoperation is considered indispensable.During the interoperability testing,a minimal number of test sequences are expected to check as many as possible implementation errors.By using minimal-complete-coverage criterion,the test sequence generation based on digraph can produce more effective test sequences.展开更多
BACKGROUND Comamonas kerstersii(C.kerstersii)infections have considered as non-pathogenic to humans,however due to new techniques such as matrix-assisted laser desorption ionization-time of flight mass spectrometry(MA...BACKGROUND Comamonas kerstersii(C.kerstersii)infections have considered as non-pathogenic to humans,however due to new techniques such as matrix-assisted laser desorption ionization-time of flight mass spectrometry(MALDI-TOF-MS),more cases have been identified.CASE SUMMARY This is the first report of a maternal patient with a C.kerstersii bacteremia following caesarean section.Due to the severity of the patient’s condition;high fever and rapidly progressing organ damage,the patient was transferred to the intensive care unit.C.kerstersii was detected by metagenomic next-generation sequencing testing.Based on the drug sensitivity test,appropriate antibiotic treatment was given and the patient recovered fully.CONCLUSION This case report confirms that the detection via MALDI-TOF-MS and metagenomic next-generation sequencing testing provides a reliable basis for the diagnosis of this rare bacterial infection.展开更多
Traditional solutions have encountered some bottleneck in improving the efficiency of protocol testing.A novel method that records the test sequence dynamically is proposed.Three dynamically reordering algorithms are ...Traditional solutions have encountered some bottleneck in improving the efficiency of protocol testing.A novel method that records the test sequence dynamically is proposed.Three dynamically reordering algorithms are brought forward in line with different fault conditions.The impact of the new method of testing efficiency is also presented.Simulation results demonstrate that the proposed solution is better than the traditional ones in terms of testing efficiency.展开更多
基金supported by the National Natural Science Foundation of China(Grant Nos.60241004,60602016 and 60602016)the National Basic Research Program of China(Grant No.2003CB314801)HUAWEI Foundation(No.YJCB2006044TS).
文摘Even if two implementations of a protocol pass the conformance testing,it cannot guarantee that they can interoperate properly;so direct testing of interoperation is considered indispensable.During the interoperability testing,a minimal number of test sequences are expected to check as many as possible implementation errors.By using minimal-complete-coverage criterion,the test sequence generation based on digraph can produce more effective test sequences.
文摘BACKGROUND Comamonas kerstersii(C.kerstersii)infections have considered as non-pathogenic to humans,however due to new techniques such as matrix-assisted laser desorption ionization-time of flight mass spectrometry(MALDI-TOF-MS),more cases have been identified.CASE SUMMARY This is the first report of a maternal patient with a C.kerstersii bacteremia following caesarean section.Due to the severity of the patient’s condition;high fever and rapidly progressing organ damage,the patient was transferred to the intensive care unit.C.kerstersii was detected by metagenomic next-generation sequencing testing.Based on the drug sensitivity test,appropriate antibiotic treatment was given and the patient recovered fully.CONCLUSION This case report confirms that the detection via MALDI-TOF-MS and metagenomic next-generation sequencing testing provides a reliable basis for the diagnosis of this rare bacterial infection.
基金supported by the National Natural Science Foundation of China (Grant No.60241004 and 60602016)the National Basic Research and Development Program of China (No.2003CB314801)+1 种基金MOE-MS Key Laboratory of Multimedia Calculation and Communication Open Foundation (No.05071801)Huawei Foundation (No.YJCB2006044TS).
文摘Traditional solutions have encountered some bottleneck in improving the efficiency of protocol testing.A novel method that records the test sequence dynamically is proposed.Three dynamically reordering algorithms are brought forward in line with different fault conditions.The impact of the new method of testing efficiency is also presented.Simulation results demonstrate that the proposed solution is better than the traditional ones in terms of testing efficiency.