期刊文献+
共找到887,191篇文章
< 1 2 250 >
每页显示 20 50 100
Acoustic Non-Destructive Testing Technology in Concrete Bridge Inspection and Pile Foundation Detection
1
作者 Wei Fu 《Journal of Architectural Research and Development》 2024年第1期20-25,共6页
This article takes the actual construction project of a certain concrete bridge project as an example to analyze the application of acoustic non-destructive testing technology in its detection.It includes an overview ... This article takes the actual construction project of a certain concrete bridge project as an example to analyze the application of acoustic non-destructive testing technology in its detection.It includes an overview of a certain bridge construction project studied and acoustic non-destructive testing technology and the application of acoustic non-destructive testing technology in actual testing.This analysis hopes to provide some guidelines for acoustic non-destructive testing of modern concrete bridge projects. 展开更多
关键词 Concrete bridge Bridge detection Acoustic detection Non-destructive testing technology
下载PDF
Research on safety control technology of high-speed railway combined test based on threatening event analysis
2
作者 Xin Bai Jiaxu Chen 《Railway Sciences》 2024年第6期731-745,共15页
Purpose–Safety management is a key point and poses a challenge in joint testing.To detect and address potential accidents’hidden dangers early,this paper conducts research on the safety control technology for high-s... Purpose–Safety management is a key point and poses a challenge in joint testing.To detect and address potential accidents’hidden dangers early,this paper conducts research on the safety control technology for high-speed railway joint tests by incorporating the concept of hazardous events.Design/methodology/approach–Aiming at ensuring the safety of high-speed railway combined inspections and trials,this paper starts from the dual prevention mechanism.It introduces the concept of threatening events,defines them and analyzes the differences between threatening events and railway accidents.The paper also proposes a cause model for threatening events in high-speed railway combined inspections and trials,based on three types of hazard sources.Furthermore,it conducts research on the control strategies for these threatening events.Findings–The research on safety control technology for high-speed railway combined operation and testing,based on the analysis of threatened events,offers a new perspective for safety management in these operations.It also provides theoretical and practical support for the transition from passive prevention to active risk pre-control,which holds significant theoretical and practical value.Originality/value–The innovation mainly includes the following three aspects:(1)Building on the traditional dual prevention mechanism,which includes risk hierarchical management and control as well as hidden danger investigation and management,a triple prevention mechanism is proposed.This new mechanism adds the management of threatening events as the third line of defense.The aim is to more comprehensively identify and address potential security risks,thereby enhancing the efficiency and effectiveness of security management.(2)In this paper,the definition of a railway threatening event is clarified,and the causative model of a high-speed railway threatening event based on three kinds of danger sources is proposed.(3)This paper puts forward the control strategy of the high-speed railway combined operation and trial,which includes five key links:identification,reporting,analysis,rectification and feedback,which provides a new perspective for the safety management of the high-speed railway combined operation and trial and has important theoretical and application value. 展开更多
关键词 High-speed railway Joint investigation and test Threatening event Source of danger Control strategy
下载PDF
昆明烟区土壤线虫数量与环境因子的Mantel Test分析
3
作者 施锘 李恩星 +9 位作者 陈江政 蒋碧霞 吴思昊 贺艳杰 王戈 王娜 白羽祥 周鹏 杜宇 李杰 《山东农业科学》 北大核心 2024年第10期153-158,共6页
为进一步明确昆明烟区影响线虫的环境因素,于2022年采集云南昆明烟区8个县(市、区)64个乡镇的320个植烟土壤样品,调查与测定样品采集地的海拔、土壤线虫数量以及土壤理化性质(pH值及有机质、水解性氮、速效钾和有效磷含量),并探讨土壤... 为进一步明确昆明烟区影响线虫的环境因素,于2022年采集云南昆明烟区8个县(市、区)64个乡镇的320个植烟土壤样品,调查与测定样品采集地的海拔、土壤线虫数量以及土壤理化性质(pH值及有机质、水解性氮、速效钾和有效磷含量),并探讨土壤线虫数量与植烟土壤环境因子之间的潜在关系。结果表明,昆明烟区土壤线虫数量一定程度上受到海拔及土壤理化性质的影响,海拔与有机质、水解性氮和速效钾呈显著正相关,pH值与有效磷呈极显著负相关,相关系数为-0.850;土壤线虫数量与土壤有效磷呈正相关,与海拔、pH值、有机质、水解性氮、速效钾呈负相关,其中与海拔、有机质和水解性氮的相关系数较大,分别为-0.751、-0.651和-0.568。通过Mantel test分析确定海拔、有机质和水解性氮含量是影响昆明烟区土壤线虫数量的重要因子。本结果可为有效防治土壤线虫提供科学依据。 展开更多
关键词 土壤线虫 海拔 土壤理化特性 Mantel test分析
下载PDF
Failure characterization of fully grouted rock bolts under triaxial testing 被引量:1
4
作者 Hadi Nourizadeh Ali Mirzaghorbanali +3 位作者 Mehdi Serati Elamin Mutaz Kevin McDougall Naj Aziz 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第3期778-789,共12页
Confining stresses serve as a pivotal determinant in shaping the behavior of grouted rock bolts.Nonetheless,prior investigations have oversimplified the three-dimensional stress state,primarily assuming hydrostatic st... Confining stresses serve as a pivotal determinant in shaping the behavior of grouted rock bolts.Nonetheless,prior investigations have oversimplified the three-dimensional stress state,primarily assuming hydrostatic stress conditions.Under these conditions,it is assumed that the intermediate principal stress(σ_(2))equals the minimum principal stress(σ_(3)).This assumption overlooks the potential variations in magnitudes of in situ stress conditions along all three directions near an underground opening where a rock bolt is installed.In this study,a series of push tests was meticulously conducted under triaxial conditions.These tests involved applying non-uniform confining stresses(σ_(2)≠σ_(3))to cubic specimens,aiming to unveil the previously overlooked influence of intermediate principal stresses on the strength properties of rock bolts.The results show that as the confining stresses increase from zero to higher levels,the pre-failure behavior changes from linear to nonlinear forms,resulting in an increase in initial stiffness from 2.08 kN/mm to 32.51 kN/mm.The load-displacement curves further illuminate distinct post-failure behavior at elevated levels of confining stresses,characterized by enhanced stiffness.Notably,the peak load capacity ranged from 27.9 kN to 46.5 kN as confining stresses advanced from σ_(2)=σ_(3)=0 to σ_(2)=20 MPa and σ_(3)=10 MPa.Additionally,the outcomes highlight an influence of confining stress on the lateral deformation of samples.Lower levels of confinement prompt overall dilation in lateral deformation,while higher confinements maintain a state of shrinkage.Furthermore,diverse failure modes have been identified,intricately tied to the arrangement of confining stresses.Lower confinements tend to induce a splitting mode of failure,whereas higher loads bring about a shift towards a pure interfacial shear-off and shear-crushed failure mechanism. 展开更多
关键词 Rock bolts Bolt-grout interface Bond strength Push test Triaxial tests
下载PDF
Discussion on the Status Quo of Non-Destructive Testing Technology in Highway Engineering and Strategies of Improving the Quality of Testing
5
作者 Fengyue Xu Junlong Xie Jie Gao 《Journal of World Architecture》 2023年第4期29-33,共5页
Highway test and detection technology play a very important role in controlling the quality of road and bridge engineering and improving the maintenance of roads and bridges.The study of highway bridge test detection ... Highway test and detection technology play a very important role in controlling the quality of road and bridge engineering and improving the maintenance of roads and bridges.The study of highway bridge test detection technology is both theoretically and practically useful.Road and bridge test and detection is a complicated task.With the development of science and technology,highway and bridge engineering test and detection technology has also made great progress.The continuous improvement of test and detection technology has brought good social benefits to road and bridge construction.This article discusses the problems in test and detection technology of highway bridges and how to improve the quality of test and detection. 展开更多
关键词 Highway engineering Non-destructive testing testing technology Quality improvement
下载PDF
Unbound^(28)O,the heaviest oxygen isotope observed:a cutting-edge probe for testing nuclear models 被引量:1
6
作者 Jian-Guo Li Bai-Shan Hu +1 位作者 Shuang Zhang Fu-Rong Xu 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第2期1-2,共2页
The beyond-dripline oxygen isotopes^(27,28)O were recently observed at RIKEN,and were found to be unbound decaying into^(24)O by emitting neutrons.The unbound feature of the heaviest oxygen isotope,^(28)O,provides an ... The beyond-dripline oxygen isotopes^(27,28)O were recently observed at RIKEN,and were found to be unbound decaying into^(24)O by emitting neutrons.The unbound feature of the heaviest oxygen isotope,^(28)O,provides an excellent test for stateof-the-art nuclear models.The atomic nucleus is a self-organized quantum manybody system comprising specific numbers of protons Z and neutrons N. 展开更多
关键词 testING QUANTUM system
下载PDF
Advances of Genetic Testing Technology in Etiology Diagnosis of Recurrent Spontaneous Abortion
7
作者 Qing Xiao Ziwei Li Jinzhi Lu 《Yangtze Medicine》 2023年第2期76-86,共11页
Recurrent spontaneous abortion (RSA) is a complex and heterogeneous disorder with multiple etiologies. Genetic factors are thought to play an important role in the etiology of RSA. With recent advances in genetic test... Recurrent spontaneous abortion (RSA) is a complex and heterogeneous disorder with multiple etiologies. Genetic factors are thought to play an important role in the etiology of RSA. With recent advances in genetic testing technologies, there has been an increasing interest in using these tools to diagnose the etiology of RSA. This review discusses the different types of genetic testing methods, such as karyotyping, chromosomal microarray analysis, next-generation sequencing, and their applications in the diagnosis of the etiology RSA. The use of genetic testing in the diagnosis of RSA has the potential to improve the accuracy of diagnosis and the understanding of the underlying mechanisms of the disorder, which could lead to better management and treatment of affected individuals. 展开更多
关键词 Recurrent Spontaneous Abortion ETIOLOGY Genetic testing technology
下载PDF
Discussion on Test and Detection Technology of Highway Asphalt Pavement
8
作者 Linli Ni 《Journal of World Architecture》 2023年第3期59-63,共5页
The road traffic industry in China has been developing rapidly in recent years.Asphalt has become the main material in road construction because of its seamless connection and short construction period,and it has an i... The road traffic industry in China has been developing rapidly in recent years.Asphalt has become the main material in road construction because of its seamless connection and short construction period,and it has an important impact on the overall quality of highway construction.Therefore,it is necessary to conduct scientific and reasonable tests and detections for highway asphalt pavement.This paper presents a discussion on the test and detection technology of highway asphalt pavement for future reference. 展开更多
关键词 HIGHWAY Asphalt pavement test and detection technology
下载PDF
Electrochemical biosensors for point-of-care testing 被引量:1
9
作者 Jinsol Kim Juho Jeong Seung Hwan Ko 《Bio-Design and Manufacturing》 SCIE EI CAS CSCD 2024年第4期548-565,共18页
Point-of-care testing(POCT)is the practice of diagnosing and monitoring diseases where the patient is located,as opposed to traditional treatment conducted solely in a medical laboratory or other clinical setting.POCT... Point-of-care testing(POCT)is the practice of diagnosing and monitoring diseases where the patient is located,as opposed to traditional treatment conducted solely in a medical laboratory or other clinical setting.POCT has been less common in the recent past due to a lack of portable medical devices capable of facilitating effective medical testing.However,recent growth has occurred in this field due to advances in diagnostic technologies,device miniaturization,and progress in wearable electronics.Among these developments,electrochemical sensors have attracted interest in the POCT field due to their high sensitivity,compact size,and affordability.They are used in various applications,from disease diagnosis to health status monitoring.In this paper we explore recent advancements in electrochemical sensors,the methods of fabricating them,and the various types of sensing mechanisms that can be used.Furthermore,we delve into methods for immobilizing specific biorecognition elements,including enzymes,antibodies,and aptamers,onto electrode surfaces and how these sensors are used in real-world POCT settings. 展开更多
关键词 Point-of-care testing(POCT) Electrochemical sensor ENZYME ANTIBODY Health care
下载PDF
A frequency servo SoC with output power stabilization loop technology for miniaturized atomic clocks 被引量:1
10
作者 Hongyang Zhang Xinlin Geng +3 位作者 Zonglin Ye Kailei Wang Qian Xie Zheng Wang 《Journal of Semiconductors》 EI CAS CSCD 2024年第6期13-22,共10页
A frequency servo system-on-chip(FS-SoC)featuring output power stabilization technology is introduced in this study for high-precision and miniaturized cesium(Cs)atomic clocks.The proposed power stabilization loop(PSL... A frequency servo system-on-chip(FS-SoC)featuring output power stabilization technology is introduced in this study for high-precision and miniaturized cesium(Cs)atomic clocks.The proposed power stabilization loop(PSL)technique,incorporating an off-chip power detector(PD),ensures that the output power of the FS-SoC remains stable,mitigating the impact of power fluctuations on the atomic clock's stability.Additionally,a one-pulse-per-second(1PPS)is employed to syn-chronize the clock with GPS.Fabricated using 65 nm CMOS technology,the measured phase noise of the FS-SoC stands at-69.5 dBc/Hz@100 Hz offset and-83.9 dBc/Hz@1 kHz offset,accompanied by a power dissipation of 19.7 mW.The Cs atomic clock employing the proposed FS-SoC and PSL obtains an Allan deviation of 1.7×10^(-11) with 1-s averaging time. 展开更多
关键词 CMOS technology atomic clock phase-locked loop output power stabilization 1PPS
下载PDF
Aquifer Test求群孔抽水试验水文地质参数
11
作者 李红伟 《中国高新科技》 2024年第5期56-57,129,共3页
在水文地质条件复杂的地区,往往采用大型的群孔抽水试验充分揭露含水层特征,获取水文地质参数。用Aquifer Test软件求解水文地质参数,则方便实用、简捷高效,可快速输出拟合图形和求参结果。Aquifer Test提供了丰富的求参方案,求参必须... 在水文地质条件复杂的地区,往往采用大型的群孔抽水试验充分揭露含水层特征,获取水文地质参数。用Aquifer Test软件求解水文地质参数,则方便实用、简捷高效,可快速输出拟合图形和求参结果。Aquifer Test提供了丰富的求参方案,求参必须结合当地当时的水文地质条件实际情况考虑,选择适合的方案和时空数据求取水文地质参数。 展开更多
关键词 群孔抽水试验 水文地质参数 Aquifer test
下载PDF
Micromechanical testing and property upscaling of planetary rocks:A critical review 被引量:1
12
作者 Yiwei Liu Guoping Zhang +1 位作者 Jiangmei Qiao Xuhai Tang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第9期1217-1241,共25页
Knowledge of the mechanical behavior of planetary rocks is indispensable for space explorations.The scarcity of pristine samples and the irregular shapes of planetary meteorites make it difficult to obtain representat... Knowledge of the mechanical behavior of planetary rocks is indispensable for space explorations.The scarcity of pristine samples and the irregular shapes of planetary meteorites make it difficult to obtain representative samples for conventional macroscale rock mechanics experiments(macro-RMEs).This critical review discusses recent advances in microscale RMEs(micro-RMEs)techniques and the upscaling methods for extracting mechanical parameters.Methods of mineralogical and microstructural analyses,along with non-destructive mechanical techniques,have provided new opportunities for studying planetary rocks with unprecedented precision and capabilities.First,we summarize several mainstream methods for obtaining the mineralogy and microstructure of planetary rocks.Then,nondestructive micromechanical testing methods,nanoindentation and atomic force microscopy(AFM),are detailed reviewed,illustrating the principles,advantages,influencing factors,and available testing results from literature.Subsequently,several feasible upscaling methods that bridge the micro-measurements of meteorite pieces to the strength of the intact body are introduced.Finally,the potential applications of planetary rock mechanics research to guiding the design and execution of space missions are environed,ranging from sample return missions and planetary defense to extraterrestrial construction.These discussions are expected to broaden the understanding of the microscale mechanical properties of planetary rocks and their significant role in deep space exploration. 展开更多
关键词 METEORITES Planetary rock mechanics Non-destructive testing Upscaling method Extraterrestrial construction Space exploration
下载PDF
Seismic performance evaluation of water supply pipes installed in a full-scale RC frame structure based on a shaking table test 被引量:1
13
作者 Wu Houli Guo Endong +2 位作者 Wang Jingyi Dai Xin Dai Chenxi 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第1期163-178,共16页
As an important part of nonstructural components,the seismic response of indoor water supply pipes deserves much attention.This paper presents shaking table test research on water supply pipes installed in a full-scal... As an important part of nonstructural components,the seismic response of indoor water supply pipes deserves much attention.This paper presents shaking table test research on water supply pipes installed in a full-scale reinforced concrete(RC)frame structure.Different material pipes and different methods for penetrating the reinforced concrete floors are combined to evaluate the difference in seismic performance.Floor response spectra and pipe acceleration amplification factors based on test data are discussed and compared with code provisions.A seismic fragility study of displacement demand is conducted based on numerical simulation.The acceleration response and displacement response of different combinations are compared.The results show that the combination of different pipe materials and different passing-through methods can cause obvious differences in the seismic response of indoor riser pipes. 展开更多
关键词 water supply pipe different materials shaking table test amplification factor seismic fragility
下载PDF
Development and technology status of energy storage in depleted gas reservoirs 被引量:1
14
作者 Jifang Wan Yangqing Sun +4 位作者 Yuxian He Wendong Ji Jingcui Li Liangliang Jiang Maria Jose Jurado 《International Journal of Coal Science & Technology》 EI CAS CSCD 2024年第2期198-221,共24页
Utilizing energy storage in depleted oil and gas reservoirs can improve productivity while reducing power costs and is one of the best ways to achieve synergistic development of"Carbon Peak–Carbon Neutral"a... Utilizing energy storage in depleted oil and gas reservoirs can improve productivity while reducing power costs and is one of the best ways to achieve synergistic development of"Carbon Peak–Carbon Neutral"and"Underground Resource Utiliza-tion".Starting from the development of Compressed Air Energy Storage(CAES)technology,the site selection of CAES in depleted gas and oil reservoirs,the evolution mechanism of reservoir dynamic sealing,and the high-flow CAES and injection technology are summarized.It focuses on analyzing the characteristics,key equipment,reservoir construction,application scenarios and cost analysis of CAES projects,and sorting out the technical key points and existing difficulties.The devel-opment trend of CAES technology is proposed,and the future development path is scrutinized to provide reference for the research of CAES projects in depleted oil and gas reservoirs. 展开更多
关键词 Depleted gas reservoirs technology and development Siting analysis Safety evaluation Compressed air energy storage
下载PDF
Development of multi-functional anchorage support dynamic-static coupling performance test system and its application
15
作者 Qi Wang Shuo Xu +4 位作者 Bei Jiang Chong Zhang Zhe Sun Jingxuan Liu Cailin Jiao 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第3期339-349,共11页
In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses... In underground engineering with complex conditions,the bolt(cable)anchorage support system is in an environment where static and dynamic stresses coexist,under the action of geological conditions such as high stresses and strong disturbances and construction conditions such as the application of high prestress.It is essential to study the support components performance under dynamic-static coupling conditions.Based on this,a multi-functional anchorage support dynamic-static coupling performance test system(MAC system)is developed,which can achieve 7 types of testing functions,including single component performance,anchored net performance,anchored rock performance and so on.The bolt and cable mechanical tests are conducted by MAC system under different prestress levels.The results showed that compared to the non-prestress condition,the impact resistance performance of prestressed bolts(cables)is significantly reduced.In the prestress range of 50–160 k N,the maximum reduction rate of impact energy resisted by different types of bolts is 53.9%–61.5%compared to non-prestress condition.In the prestress range of 150–300 k N,the impact energy resisted by high-strength cable is reduced by76.8%–84.6%compared to non-prestress condition.The MAC system achieves dynamic-static coupling performance test,which provide an effective means for the design of anchorage support system. 展开更多
关键词 Anchorage support system Development of test system Dynamic-static coupling test Combined stress
下载PDF
C-CORE:Clustering by Code Representation to Prioritize Test Cases in Compiler Testing
16
作者 Wei Zhou Xincong Jiang Chuan Qin 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第5期2069-2093,共25页
Edge devices,due to their limited computational and storage resources,often require the use of compilers for program optimization.Therefore,ensuring the security and reliability of these compilers is of paramount impo... Edge devices,due to their limited computational and storage resources,often require the use of compilers for program optimization.Therefore,ensuring the security and reliability of these compilers is of paramount importance in the emerging field of edge AI.One widely used testing method for this purpose is fuzz testing,which detects bugs by inputting random test cases into the target program.However,this process consumes significant time and resources.To improve the efficiency of compiler fuzz testing,it is common practice to utilize test case prioritization techniques.Some researchers use machine learning to predict the code coverage of test cases,aiming to maximize the test capability for the target compiler by increasing the overall predicted coverage of the test cases.Nevertheless,these methods can only forecast the code coverage of the compiler at a specific optimization level,potentially missing many optimization-related bugs.In this paper,we introduce C-CORE(short for Clustering by Code Representation),the first framework to prioritize test cases according to their code representations,which are derived directly from the source codes.This approach avoids being limited to specific compiler states and extends to a broader range of compiler bugs.Specifically,we first train a scaled pre-trained programming language model to capture as many common features as possible from the test cases generated by a fuzzer.Using this pre-trained model,we then train two downstream models:one for predicting the likelihood of triggering a bug and another for identifying code representations associated with bugs.Subsequently,we cluster the test cases according to their code representations and select the highest-scoring test case from each cluster as the high-quality test case.This reduction in redundant testing cases leads to time savings.Comprehensive evaluation results reveal that code representations are better at distinguishing test capabilities,and C-CORE significantly enhances testing efficiency.Across four datasets,C-CORE increases the average of the percentage of faults detected(APFD)value by 0.16 to 0.31 and reduces test time by over 50% in 46% of cases.When compared to the best results from approaches using predicted code coverage,C-CORE improves the APFD value by 1.1% to 12.3% and achieves an overall time-saving of 159.1%. 展开更多
关键词 Compiler testing test case prioritization code representation
下载PDF
Inflow and outflow permeability tests in a very soft clay under low stresses
17
作者 J.W.S.Vargas F.A.B.Danziger +1 位作者 F.R.Lopes T.Lunne 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第8期3270-3283,共14页
In situ inflow and outflow permeability tests with the BAT probe at SarapuíII soft clay test site are presented.A description of the BAT permeability test is provided,discussing its advantages and shortcomings,es... In situ inflow and outflow permeability tests with the BAT probe at SarapuíII soft clay test site are presented.A description of the BAT permeability test is provided,discussing its advantages and shortcomings,especially in the case of very soft clays under low stresses.Pore pressures were monitored during probe installation and were found to be slightly lower than piezocone u2 pore pressures,consistent with the position of the filter.The role of filter tip saturation was investigated after the usual saturation procedure provided an unsatisfactory pore pressure response during probe installation.Results show that the vacuum saturation procedure provides adequate response during installation and increases the reliability of the coefficient of permeability determination in early measurements.Both inflow and outflow tests yielded similar results,indicating that careful execution of the test can lead to good test repeatability regardless of the loading condition.Various sequences of alternated inflow and outflow tests have yielded similar results,indicating that soil reconsolidation and filter clogging were negligible in the tests performed.Data are presented concerning the relationship between index parameters and the in situ coefficient of permeability for SarapuíII clay,which plot outside the range of existing databases. 展开更多
关键词 Permeability test Soft clay BAT probe Inflow and outflow tests
下载PDF
Evaluation of urea breath test as a diagnostic tool for Helicobacter pylori infection in adult dyspeptic patients
18
作者 Zeinab Nabil Ahmed Said Asmaa Mohamed El-Nasser 《World Journal of Gastroenterology》 SCIE CAS 2024年第17期2302-2307,共6页
In this editorial,we discuss the article in the World Journal of Gastroenterology.The article conducts a meta-analysis of the diagnostic accuracy of the urea breath test(UBT),a non-invasive method for detecting Helico... In this editorial,we discuss the article in the World Journal of Gastroenterology.The article conducts a meta-analysis of the diagnostic accuracy of the urea breath test(UBT),a non-invasive method for detecting Helicobacter pylori(H.pylori)infection in humans.It is based on radionuclide-labeled urea.Various methods,both invasive and non-invasive,are available for diagnosing H.pylori infection,inclu-ding endoscopy with biopsy,serology for immunoglobulin titers,stool antigen analysis,and UBT.Several guidelines recommend UBTs as the primary choice for diagnosing H.pylori infection and for reexamining after eradication therapy.It is used to be the first choice non-invasive test due to their high accuracy,specificity,rapid results,and simplicity.Moreover,its performance remains unaffected by the distribution of H.pylori in the stomach,allowing a high flow of patients to be tested.Despite its widespread use,the performance characteristics of UBT have been inconsistently described and remain incompletely defined.There are two UBTs available with Food and Drug Administration approval:The 13C and 14C tests.Both tests are affordable and can provide real-time results.Physicians may prefer the 13C test because it is non-radioactive,compared to 14C which uses a radioactive isotope,especially in young children and pregnant women.Although there was heterogeneity among the studies regarding the diagnostic accuracy of both UBTs,13C-UBT consistently outperforms the 14C-UBT.This makes the 13C-UBT the preferred diagnostic approach.Furthermore,the provided findings of the meta-analysis emphasize the significance of precise considerations when choosing urea dosage,assessment timing,and measurement techniques for both the 13C-UBT and 14C-UBT,to enhance diagnostic precision. 展开更多
关键词 Helicobacter pylori Urea breath test DIAGNOSIS Diagnostic test accuracy META-ANALYSIS
下载PDF
Real-world utility of serological tests in patients with suspected scrub typhus in the Republic of Korea:A single-center,retrospective,observational study
19
作者 Seulki Kim A Reum Kim +2 位作者 Seungjin Lim Su Jin Lee Moonsuk Bae 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2024年第6期273-280,I0004,I0005,共10页
Objective:Serological tests are widely used for scrub typhus diagnosis;however,their limitations are evident.This study aims to assess their practical value in clinical settings.Methods:We analyzed the data of adult p... Objective:Serological tests are widely used for scrub typhus diagnosis;however,their limitations are evident.This study aims to assess their practical value in clinical settings.Methods:We analyzed the data of adult patients with suspected scrub typhus who visited a tertiary care hospital in the Republic of Korea from September to December from 2019 to 2021.The included patients had an acute fever and at least one of the following ten secondary findings:myalgia,skin rash,eschar,headache,thrombocytopenia,increased liver enzyme levels,lymphadenopathy,hepatomegaly,splenomegaly,and pleural effusion.The diagnoses were grouped as scrub typhus or other diseases by two infectious disease physicians.Results:Among 136 patients who met the eligibility criteria,109 had scrub typhus and 27 had different diseases.Single and paired total antibodies using immunofluorescence assay(IFA),and total antibodies using immunochromatography-based rapid diagnostic testing(ICT)were measured in 98%,22%,and 75%of all patients,respectively.Confirmation using paired samples for scrub typhus was established at a median of 11[interquartile range(IQR)10-16]days following the first visit.Among the 82 admitted patients,the median admission time was 9(IQR 7-13)days.According to IFA,58(55%)patients with scrub typhus had total immunoglobulin titers≥1:320,while 23(85%)patients with other disease had titers<1:320.Positive ICT results were observed in 64(74%)patients with scrub typhus and 10(67%)patients with other diseases showed negative ICT results.Conclusions:Serological testing for scrub typhus is currently insufficient for decision-making in clinical practice. 展开更多
关键词 Scrub typhus Serological test Immunofluorescence assay IMMUNOCHROMATOGRAPHY Rapid detecting test
下载PDF
Urea breath test for Helicobacter pylori infection in adult dyspeptic patients: A meta-analysis of diagnostic test accuracy
20
作者 Fabian Fellipe Bueno Lemos Caroline Tianeze de Castro +9 位作者 Marcel Silva Luz Gabriel Reis Rocha Gabriel Lima Correa Santos Luís Guilherme de Oliveira Silva Mariana Santos Calmon Cláudio Lima Souza Ana Carla Zarpelon-Schutz Kádima Nayara Teixeira Dulciene Maria de Magalhães Queiroz Fabrício Freire de Melo 《World Journal of Gastroenterology》 SCIE CAS 2024年第6期579-598,共20页
BACKGROUND Helicobacter pylori(H.pylori)infection has been well-established as a significant risk factor for several gastrointestinal disorders.The urea breath test(UBT)has emerged as a leading non-invasive method for... BACKGROUND Helicobacter pylori(H.pylori)infection has been well-established as a significant risk factor for several gastrointestinal disorders.The urea breath test(UBT)has emerged as a leading non-invasive method for detecting H.pylori.Despite numerous studies confirming its substantial accuracy,the reliability of UBT results is often compromised by inherent limitations.These findings underscore the need for a rigorous statistical synthesis to clarify and reconcile the diagnostic accuracy of the UBT for the diagnosis of H.pylori infection.AIM To determine and compare the diagnostic accuracy of 13C-UBT and 14C-UBT for H.pylori infection in adult patients with dyspepsia.METHODS We conducted an independent search of the PubMed/MEDLINE,EMBASE,and Cochrane Central databases until April 2022.Our search included diagnostic accuracy studies that evaluated at least one of the index tests(^(13)C-UBT or ^(14)C-UBT)against a reference standard.We used the QUADAS-2 tool to assess the methodo-logical quality of the studies.We utilized the bivariate random-effects model to calculate sensitivity,specificity,positive and negative test likelihood ratios(LR+and LR-),as well as the diagnostic odds ratio(DOR),and their 95%confidence intervals.We conducted subgroup analyses based on urea dosing,time after urea administration,and assessment technique.To investigate a possible threshold effect,we conducted Spearman correlation analysis,and we generated summary receiver operating characteristic(SROC)curves to assess heterogeneity.Finally,we visually inspected a funnel plot and used Egger’s test to evaluate publication bias.endorsing both as reliable diagnostic tools in clinical practice.CONCLUSION In summary,our study has demonstrated that ^(13)C-UBT has been found to outperform the ^(14)C-UBT,making it the preferred diagnostic approach.Additionally,our results emphasize the significance of carefully considering urea dosage,assessment timing,and measurement techniques for both tests to enhance diagnostic precision.Nevertheless,it is crucial for researchers and clinicians to evaluate the strengths and limitations of our findings before implementing them in practice. 展开更多
关键词 Helicobacter pylori Urea breath test DIAGNOSIS Diagnostic test accuracy META-ANALYSIS
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部