Curriculum Ideological and Political Teaching and Practice of Study Tour Course Design in Higher Vocational Colleges: A Case Study of Qingdao Preschool Education College

Curriculum ideology and politics are critical for colleges and universities to fulfill theirfundamental mission of fostering moral and intellectual development. Within this framework, professionalcourses serve as the primary vehicles for integrating ideological and political education. Specifically, inthe field of study tours, the Study Tour Course Design emerges as a pivotal component for actualizingthe educational objectives of such programs. To construct a robust ideological and political curriculum,it is essential to devise a comprehensive system that aligns with professional teaching standards, industrybenchmarks, and vocational skill requirements. This involves a thorough exploration of ideologicaland political elements within the curriculum, ensuring their seamless integration throughout the coursedevelopment process.

A Survey Study of Kindergarten Teachers’Use of ChatGPT to Support Instructional Design

With the rapid development of information technology,Artificial Intelligence(AI)is gradually applied to a wide range of fields,especially the powerful ability of ChatGPT to bring infinite possibilities for education,but teachers’attitudes toward using it are not yet clear.The study investigates the use of ChatGPT by kindergarten teachers to support instructional design using questionnaires and interviews to explore the attitudes and perceptions of kindergarten teachers toward its use.The results indicate that kindergarten teachers hold positive preferences for technology acceptance,perceived self-efficacy,and learning attitudes toward using ChatGPT for instructional design.Meanwhile,the study argues that more research is needed in the future to focus on how kindergarten teachers can aptly use ChatGPT to improve the quality of instruction in realistic instructionenvironments.

Corpus-based Translation Class Design Study

This essay accesses to the approach of corpus applied to translation teaching, in order to improve the teaching methods, lay the foundation for the translation teaching reform, cultivate students research ability, and finally to establish a new type of translation teaching design-- ＂ability-development-oriented design＂. Also, this paper takes the word ＂good＂ for example, looking for the general rules to translate it and its common collocation, in order to design a translation class. Corpus-based learning and teaching provides us a new feasible way of translation class.

Preliminary Study on the Application of Color in the Landscape Design

In experiencing the modern landscape,color is perceived through the sight which relies on both the concrete substance and an Abstract matter-light.In this research,through analyzing the visual property and psychological perception,the 'color' used in modern landscape design is interpreted,and the application forms and methods of color in landscape design are explained in terms of the application and technique of color in site culture.

Preclinical in vivo research of magnesium-based implants for fracture treatment: A systematic review of animal model selection and study design

Background:Degradable magnesium implants are promising for clinical fracture treatment,providing less stress-shielding mechanical support and superior bone-strengthening benefits to traditional materials.The quality of preclinical research is essential for developing Mg implants;however,there are considerable variations in the model selection and study design in published studies,posing challenges for safe and effective clinical translation of lab discoveries.Objective:The purpose of this systematic review is to investigate the current progress on in vivo research of Mg implants for fracture treatment,focusing on model selection,Mg materials,implant design,methodological and analyzing techniques,aiming to provide comprehensive guidance for future preclinical research.Materials and methods:Pub Med and Embase online databases were searched to identify researches investigating Mg implants in animal models of fracture from 1960 to December 2019,using a combination of keywords:magnesium and fracture.Eligible studies were included without language restriction.Data extraction was conducted for qualitative analysis.Meta-analysis was not performed due to extensive heterogeneities among studies.Results:Twenty studies published from 2014 to 2019 were included.Publication information,animal model,methodological quality,implants preparation,and evaluation techniques were extracted.The methodological assessment revealed low to high risk of bias among studies.Both rodent and non-rodent species were selected,and the anatomical sites for inducing fractures included both cranial-facial and limb bones.Pure Mg and alloys with or without surface modification were evaluated,covering implant designs of both intra-medullary and extra-medullary fixation.Radiological and histological evaluations were commonly conducted.Conclusions:Published in vivo evidence confirmed the role of Mg-based implants in promoting fracture healing.However,considering heterogeneity in animal selection,implant preparation,and evaluation methods,there still lacks a standardized reference model.By analyzing the information extracted from included studies,the systematic review may facilitate planning and conducting preclinical research with translational perspective.

Applying“First Principles of Instruction”as a Design Theory of the EFL Classroom:Findings from an Empirical Study

How to benefit the learners learning English as a foreign language(EFL)from the aspect of instructional design aroused the concerns of many teachers and researchers.The main purpose of this study is to address the question of how teachers can design and implement EFL classroom that benefit the learners.Specifically,the“First Principles of Instruction,”advocated by Merrill(2002),was applied by the English teachers to conduct their day-to-day pedagogical practices.The corresponding effects of this theory in designing EFL classroom activities were reported in this study.Two research questions are formulated as follows:(1)Does the“First Principles of Instruction”benefit the EFL classroom designing in the aspect of student achievement?If yes,what is the effect?(2)How do the English teachers perceive the“First Principles of Instruction”to design EFL classroom?While observing the EFL classroom activities and interviewing the college English teachers,an empirical study was done to perceive how college English teachers could best apply these principles to design EFL classroom activities.

STUDY ON THERMAL EXPANSIONCOEFFICIENT AND DESIGN FOR ZERO-EXPANSION OF SlNGLE AND HYBRIDMULTI-DIRECTIONAL COMPOSITES

AbstractThermal expansion properties of single and hybrid multi-directional composites fromr.t. to 150℃ are studied. The theoretical formulae for predicting coefficient of thermal ex-pansion (CTE) value are established. In the experiments, carbon/glasa andcarbon / Keviar are accepted to be the hybrid form. The variation of CTE values of hybridcomposites with structure parameter is analyzed. Besides, hybrid composites with zeroCTE arc studied and designed. And some typical ply forms of laminates with zero CTE arepresented. The investigation shows that it is easier for hybrid multi-directional compositesto meet the requirements of zero-expansion.

A Study of Design Optimization Using Response Surface Analysis and Fabricaiton MEMS Probe Tip

In semiconductor manufacturing process, probe station that is testing equipment is important. Inspection step is for detecting defects on semiconductor before the packaging. Probe card is a part of probe station and contains probe tip that contacts to semiconductor. Through probe tip, it can inspect defects of semiconductor. In this paper, optimization method is used with response surface analysis to design MEMS type probe tip. And fabricating probe tip uses maskless lithography, electro-plating and lapping process.

Large Cohort Data Based Group or Community Disease Prevention Design Strategy: Strong Heart Study

Background and Objective: A multitude of large cohort studies have data on incidence rates and predictors of various chronic diseases. However, approaches for utilization of these costly collected data and translation of these?valuable results to inform and guide clinical disease prevention practice are?not well developed. In this paper we proposed a novel conceptual group/community disease prevention design strategy based on large cohort study data. Methods and Results: The data from participants (n = 3516;2056 women) aged 45 to 74 years and the diabetes risk prediction model from Strong Heart Study were used. The Strong Heart Study is a population-based cohort study of cardiovascular disease and its risk factors in American Indians. A conceptual group/community disease prevention design strategy based on large cohort data was initiated. The application of the proposed strategy for group diabetes prevention was illustrated. Discussion: The strategy may provide reasonable solutions to the prevention design issues. These issues include complex associations of a disease with its combined and correlated risk factors, individual differences, choosing intervention risk factors and setting their appropriate, attainable, gradual and adaptive goal levels for different subgroups, and assessing effectiveness of the prevention program. Conclusions: The strategy and methods shown in the illustration example can be analogously adopted and applied for other diseases preventions. The proposed strategy for a target group/community in a population provides a way to translate and apply epidemiological study results to clinical disease prevention practice.

Large Cohort Data Based Cost-Effective Disease Prevention Design Strategy: Strong Heart Study

Background and Objective: A multitude of large cohort studies have collected data on incidence and covariates/risk factors of various chronic diseases. However, approaches for utilization of these large data and translation of the valuable results to inform and guide clinical disease prevention practice are not well developed. In this paper, we proposed, based on large cohort study data, a novel conceptual cost-effective disease prevention design strategy for a target group when it is not affordable to include everyone in the target group for intervention. Methods and Results: Data from American Indian participants (n = 3516;2056 women) aged 45 - 74 years in the Strong Heart Study, the diabetes risk prediction model from the study, a utility function, and regression models were used. A conceptual cost-effective disease prevention design strategy based on large cohort data was initiated. The application of the proposed strategy for diabetes prevention was illustrated. Discussion: The strategy may provide reasonable solutions to address cost-effective prevention design issues. These issues include complex associations of a disease with its significant risk factors, cost-effectively selecting individuals at high risk of developing disease to undergo intervention, individual differences in health conditions, choosing intervention risk factors and setting their appropriate, attainable, gradual and adaptive goal levels for different subgroups, and assessing effectiveness of the prevention program. Conclusions: The strategy and methods shown in the illustrative example can also be analogously adopted and applied to other diseases preventions. The proposed strategy provides a way to translate and apply epidemiological study results to clinical disease prevention practice.

A Comparative Study on That Design of Agricultural Canal in Ecological and Traditional Renovation of Agricultural Land—Take a Project Area in Lingchuan County, Guilin City, Guangxi, China as an Example

In the current context of vigorously promoting the construction of ecological civilization, land consolidation in the construction of the constant pursuit of ecological design, to achieve sustainable use of land resources, China has made great progress in ecological land consolidation. In this paper, through the comparison of flow design and cross section design of agricultural canal design in ecological land remediation and traditional land remediation, the characteristic design of some agricultural canals in ecological land remediation was introduced, and the ecological, social and economic benefits of two land remediation methods were systematically analyzed. The analysis shows that ecological agricultural canals play a great role in protecting biodiversity, alleviating the contradiction between people and land, saving energy, purifying water resources and improving land quality, the research result has provided the basis and the model for the land consolidation in carrying on the ecology type ditch design.

Influence of pontic design of anterior fixed dental prosthesis on speech: A clinical case study

BACKGROUND The pontic design of fixed dental prostheses(FDPs)is strongly associated with the phonetic function,and the phonetic function of anterior FDPs with different pontic designs remains understudied.AIM To investigate the immediate and short-term influence of pontic design of anterior FDPs on Chinese speech in a clinical case using objective acoustic analysis.METHODS Two FDPs with two types of pontic design(saddle pontic and modified ridge lap pontic)were fabricated for one patient with maxillary anterior teeth missing.The acoustic analysis of patient’s articulation was conducted immediately after wearing the FDPs and 1 wk after wearing these FDPs.RESULTS The effect of FDP on Chinese vowels(/a/,/o/,/e/,/i/,/u/,and/ü/)was insignificant,because the recovery of vowel distortion occurred within 1 wk for both FDPs.Three(/f/,/s/,and/sh/)of eight Chinese fricative consonants were found to have obvious distortions,and the/s/sound distortion last for more than 1 wk for the patient wearing FDP with modified ridge lap pontic design.CONCLUSION The influence of anterior FDP on articulation of Chinese vowels is insignificant,while the articulation of Chinese fricative consonants is more susceptible.When fabricating anterior FDPs for patients with speech related professions,saddle pontic design can be an alternative option compared with modified ridge lap pontic design.

Exploration of nature-based biomimetic approach in landscape architectural design: parametric study of candelabra model design

This research provides an exploration of a biomimetic approach in the process of designing a candelabra model using linear shaped leaves of a Bell flower.The design process described in this research contains two steps:biological and geometrical.In the first biological step,a proper model for the creation of an urban element was found from nature in a Bell flower(Campanula persicifolia L.).The upper leaves of the selected plant,which are small with a linear spear and sharpening at the top,were chosen for the modeling process.The second step included applying two geometrical methods,i.e.,Voronoi diagrams and Delaunay triangulation.A geometrical leaf form of the selected plant species and the modeling process were obtained using aparametric modeling software,Blender.Using different Blender plug-ins and modifiers,Delaunay triangulation and Voronoi diagram were implemented by marking the starting points on the leaf form in the image data source,adjusting the Delaunay triangulation parameters,and creating Voronoi diagrams in which the Voronoi points were located at the shortest distance from the edges of the Voronoi polygon.Consequently,a three dimensional model of a candelabra was developed through this study.

A Study on the Usability of Semiotics in Graphic Design

Currently, The current flat design has become a mainstream approach is widely used in web design, computer and mobile phone systems, interface design. In graphic design, graphic symbol design is increasingly being taken seriously and use minimalist design symbols often appear in print design plane, PPT presentations, public areas, identity-oriented system like. This paper discusses the design of graphical symbols flat in graphic design use need to make the audience cognitive ability, graphic symbols standardized principles, design principles angles for effective information design to achieve efficient information communication. Materialized mostly graphic image symbols, and mostly flat graphic indicator; flat screen symbol by the proposed development materialized symbol interface evolved. Materialized the graphical interface and the graphical interface is flat coexist and cannot replace each other. During the design, the designer should be based on the advantages and disadvantages of the two styles complement each other interfaces, common graphical interface design services.

Study on Application of Virtual Reality Technique in Environmental Artistic Design

With the advent of the information age, people＇ s lives have been changed unknowingly owing to lots of modem technology means. For the environmental artistic design, the traditional mode of environmental artistic design is broken through after the emergence of computer technology and virtual reality technique, which makes the scheme and application of virtual reality technique in environmental artistic design to own more practical value. In this paper, the virtual reality technique and its practical application in environmental artistic design are set forth, and the profound influence on the actual design by the virtual reality technique is studied with expectation of enlightenment for broadening the thought of environmental artistic design.

Improving Biomarker Development and Assessment:Standards for Study Design

Background:The Early Detection Research Network (EDRN), NCI funded and investigator driven, has the mission to evaluate biomarkers for their clinical utilities in cancer risk prediction, diagnosis, early detection,

How to use the Surveillance,Epidemiology,and End Results(SEER)data:research design and methodology

In the United States(US),the Surveillance,Epidemiology,and End Results(SEER)program is the only comprehensive source of population-based information that includes stage of cancer at the time of diagnosis and patient survival data.This program aims to provide a database about cancer incidence and survival for studies of surveillance and the development of analytical and methodological tools in the cancer field.Currently,the SEER program covers approximately half of the total cancer patients in the US.A growing number of clinical studies have applied the SEER database in various aspects.However,the intrinsic features of the SEER database,such as the huge data volume and complexity of data types,have hindered its application.In this review,we provided a systematic overview of the commonly used methodologies and study designs for retrospective epidemiological research in order to illustrate the application of the SEER database.Therefore,the goal of this review is to assist researchers in the selection of appropriate methods and study designs for enhancing the robustness and reliability of clinical studies by mining the SEER database.

Design and compilation of urban geomorpholo-gical maps——A case study in Chongqing city

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Translation Studies的名与实——再议“Translation Studies”一词的汉译

“Translation Stud ies”一词的汉译,我国学界有不同的主张。其实,该词具有“翻译学”和“翻译研究”的双重译名,我们应以“名实相符”为原则,根据其不同所指赋予其不同的汉译名予以区分。同时,依据这一原则对我国引进的部分国外学术专著的书名的汉译应进行修改。

Binding Mechanism and Molecular Design of Benzimidazole/Benzothiazole Derivatives as Potent Abl T3151 Mutant Inhibitors

Despite the efficacy of imatinib therapy in chronic myelogenous leukemia, the development of drug-resistant Abl mutants, especially the most difficult overcoming T3151 mutant, makes the search for new Abl T3151 inhibitors a very interesting challenge in medicinal chem- istry. In this work, a multistep computational framework combining the three dimensional quantitative structure-activity relationship （3D-QSAR）, molecular docking, molecular dy- namics （MD） simulation and binding free energy calculation, was performed to explore the structural requirements for the Abl T315I activities of benzimidazole/benzothiazole derivatives and the binding mechanism between the inhibitors and Abl T315I. The established 3D-QSAR models exhibited satisfactory internal and external predictability. Docking study elucidated the comformations of compounds and the key amino acid residues at the binding pocket, which were confirmed by MD simulation. The binding free energies correlated well with the experimental activities. The MM-GBSA energy decomposition revealed that the van der Waals interaction was the major driving force for the interaction between the ligands and Abl T3151. The hydrogen bond interactions between the inhibitors and Met318 also played an important role in stablizing the binding of compounds to Abl T315I. Finally, four new compounds with rather high Abl T3151 activities were designed and presented to experimenters for reference.