A novel crystal with the molecular formula [Pd（DCA）（bipy）]2 [Pd（bipy）Cl2 ]·6.75H2O was formed by PdCl2 with disodium demethylcantharate （Na2 （DCA）,DCA2= 7-oxa-bicyclo[2.2.1]heptane-2,3-bicarboxylate） an...A novel crystal with the molecular formula [Pd（DCA）（bipy）]2 [Pd（bipy）Cl2 ]·6.75H2O was formed by PdCl2 with disodium demethylcantharate （Na2 （DCA）,DCA2= 7-oxa-bicyclo[2.2.1]heptane-2,3-bicarboxylate） and 2,2-bipyidine （bipy） through the hydrothermal method.The complex was characterized by elemental analysis and infrared spectroscopy.The structure of the complex was determined by single-crystal X-ray diffraction,which is of triclinic system,space group P1 with a=13.6818（7）,b=14.8426（8）,c=15.0043（8）,α=97.319（3）,β=92.521（3）,γ=105.776（2）°,V=2898.4（3） 3,Dc=1.545 g·cm-3,Z=1,F（000）=1420,S=0.852,the final R=0.0525 and wR=0.1777 for 13634 observer reflections （I〉2σ（I））.The binding reaction of the complex with ct-DNA and bovine serum albumin （BSA） was studied by fluorescence spectroscopy.The results indicated that the complex binds to ct-DNA via the partial intercalation.The binding constant K A of the complex interaction with BSA was 3.98×10 5 L·mol-1 and one binding site would be formed.The antiproliferative activity of the complex against human hepatoma cells （SMMC7721） in vitro is much higher than that of Na 2 （DCA）.展开更多
A mononuclear complex, cis-1,10-phenanthroline-palladium(Ⅱ)(THF)2]dinitrate (THF = tetrahydrofuran) [Pd(C10H8N2)(C4H8O)2](NO3)2 1, has been prepared and structurally characterized by single-crystal X-ray diffraction....A mononuclear complex, cis-1,10-phenanthroline-palladium(Ⅱ)(THF)2]dinitrate (THF = tetrahydrofuran) [Pd(C10H8N2)(C4H8O)2](NO3)2 1, has been prepared and structurally characterized by single-crystal X-ray diffraction. The crystal belongs to monoclinic system, space group P21/c with a = 7.881(1), b = 27.371(3), c = 10.178(1) ? ?= 103.313(3)? V = 2136.5(4) 3, Mr = 554.83, Dc = 1.725 g/cm3, Z = 4, F(000) = 1128 and (MoK) = 0.926 mm-1. The structure was refined to R = 0.0678 and wR = 0.1651 for 1687 observed reflections with I > 2(I). It is revealed that the central Pd(Ⅱ) ion in the title complex is bonded to two THF and two phenanthroline molecules in a cis-configuration to form the coordination geometry, deviating slightly from the square plane.展开更多
A novel ion-pair palladium（Ⅱ） compound, （NOzBzPy）2[Pd（dmit）2] （NO2BzPy^＋ = 1-（4-nitrobenzyl）pyridinium, dmit^2- = 2-thioxo-1,3-dithiole-4,5-bis（thiolate））, was synthesized and characterized by single-cry...A novel ion-pair palladium（Ⅱ） compound, （NOzBzPy）2[Pd（dmit）2] （NO2BzPy^＋ = 1-（4-nitrobenzyl）pyridinium, dmit^2- = 2-thioxo-1,3-dithiole-4,5-bis（thiolate））, was synthesized and characterized by single-crystal X-ray structure determination. This compound crystallizes in the monoclinic system, space group P21/n with a = 10.4463（11）, b = 8.5627（9）, e = 20.017（2）A, β = 97.7730（10）°, V = 1774.1（3）A^3, Z = 2, C30H22N4O4S10Pd, Mr = 929.52, Dc = 1.740 g/cm^3,μ = 1.155 mm^-1, S = 1.006, F（000） = 936, R = 0.0354 and wR = 0.0675. The most intriguing general structural feature of the compound is the completely segregated columnar stacks of anions and cations. There exist hydrogen-bonding interactions within the cation column.展开更多
基金Supported by the Natural Science Foundation of Zhejiang Province (Y407301)
文摘A novel crystal with the molecular formula [Pd（DCA）（bipy）]2 [Pd（bipy）Cl2 ]·6.75H2O was formed by PdCl2 with disodium demethylcantharate （Na2 （DCA）,DCA2= 7-oxa-bicyclo[2.2.1]heptane-2,3-bicarboxylate） and 2,2-bipyidine （bipy） through the hydrothermal method.The complex was characterized by elemental analysis and infrared spectroscopy.The structure of the complex was determined by single-crystal X-ray diffraction,which is of triclinic system,space group P1 with a=13.6818（7）,b=14.8426（8）,c=15.0043（8）,α=97.319（3）,β=92.521（3）,γ=105.776（2）°,V=2898.4（3） 3,Dc=1.545 g·cm-3,Z=1,F（000）=1420,S=0.852,the final R=0.0525 and wR=0.1777 for 13634 observer reflections （I〉2σ（I））.The binding reaction of the complex with ct-DNA and bovine serum albumin （BSA） was studied by fluorescence spectroscopy.The results indicated that the complex binds to ct-DNA via the partial intercalation.The binding constant K A of the complex interaction with BSA was 3.98×10 5 L·mol-1 and one binding site would be formed.The antiproliferative activity of the complex against human hepatoma cells （SMMC7721） in vitro is much higher than that of Na 2 （DCA）.
基金We thank NNSFC (No. 90206013) foundation for the financial support of this research
文摘A mononuclear complex, cis-1,10-phenanthroline-palladium(Ⅱ)(THF)2]dinitrate (THF = tetrahydrofuran) [Pd(C10H8N2)(C4H8O)2](NO3)2 1, has been prepared and structurally characterized by single-crystal X-ray diffraction. The crystal belongs to monoclinic system, space group P21/c with a = 7.881(1), b = 27.371(3), c = 10.178(1) ? ?= 103.313(3)? V = 2136.5(4) 3, Mr = 554.83, Dc = 1.725 g/cm3, Z = 4, F(000) = 1128 and (MoK) = 0.926 mm-1. The structure was refined to R = 0.0678 and wR = 0.1651 for 1687 observed reflections with I > 2(I). It is revealed that the central Pd(Ⅱ) ion in the title complex is bonded to two THF and two phenanthroline molecules in a cis-configuration to form the coordination geometry, deviating slightly from the square plane.
基金Supported by the National Natural Science Foundation of China (No. 20371002)the Natural Science Foundation of Education Commission of Anhui Province (No. kj2007b092, kj2008b004)
文摘A novel ion-pair palladium（Ⅱ） compound, （NOzBzPy）2[Pd（dmit）2] （NO2BzPy^＋ = 1-（4-nitrobenzyl）pyridinium, dmit^2- = 2-thioxo-1,3-dithiole-4,5-bis（thiolate））, was synthesized and characterized by single-crystal X-ray structure determination. This compound crystallizes in the monoclinic system, space group P21/n with a = 10.4463（11）, b = 8.5627（9）, e = 20.017（2）A, β = 97.7730（10）°, V = 1774.1（3）A^3, Z = 2, C30H22N4O4S10Pd, Mr = 929.52, Dc = 1.740 g/cm^3,μ = 1.155 mm^-1, S = 1.006, F（000） = 936, R = 0.0354 and wR = 0.0675. The most intriguing general structural feature of the compound is the completely segregated columnar stacks of anions and cations. There exist hydrogen-bonding interactions within the cation column.
