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Early development of peer dominance relationships in a captive group of Japanese macaques Macaca fuscata 被引量:1
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作者 RIZALDI Kunio WATANABE 《Current Zoology》 SCIE CAS CSCD 北大核心 2010年第2期190-197,共8页
We studied early development of peer dominance relationships in a captive group of Japanese macaques Macaca fuscata fuscata at the Primate Research Institute of Kyoto University. This study aims to give detailed descr... We studied early development of peer dominance relationships in a captive group of Japanese macaques Macaca fuscata fuscata at the Primate Research Institute of Kyoto University. This study aims to give detailed descriptions on characteristic patterns of maternal rank acquisition from infant to juvenile. Focal subjects were 22 young monkeys belonging to three cohorts born in 2002, 2003 and 2005. Data were collected with a total 2130 sessions of 30-minute continuous recording of focal subjects combined with all occurrence-sampling methods. The onset of aggressive behavior varied per cohort and was delayed in cohorts with fewer close-aged associates. More than 60% of dyadic combinations in agonistic interactions between peers were unidirectional throughout the study period. Although some bidirectional interactions could have involved unstable relationships between particular individuals, most of the bidirectional interactions included a few continuous series of alternating one-sided interactions. A linear order could be found among peers from the first appearance of aggressive behavior, and nearly 90% of those dyads were concordant with that of their mother's rank order. Young males were responsible for most of the dominance relations that would not be predicted based on their mother's rank. These results suggest that infant monkeys may recognize their own social status relative to their opponent's before onset of aggressive behavior and adjust themselves into the matrilineal rank system accordingly. 展开更多
关键词 Aggressive behavior dominance relationship Early development japanese macaque
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On the beginning of the Japanese Upper Paleolithic:A review of recent archaeological and anthropological evidence
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作者 Hiroyuki SATO Kazuki MORISAKI 《人类学学报》 CSSCI CSCD 北大核心 2024年第3期470-487,共18页
The beginning of the Japanese Upper Paleolithic has mainly been examined using two major models:the Middle Paleolithic evolutionary model within the archipelago and the continental Upper Paleolithic diffusion/migratio... The beginning of the Japanese Upper Paleolithic has mainly been examined using two major models:the Middle Paleolithic evolutionary model within the archipelago and the continental Upper Paleolithic diffusion/migration model.However,recent archeological data from Japan and nearby countries are challenging such simple models.This paper critically reviews previous chronology of the Japanese Paleolithic,including possible Lower and Middle Paleolithic(LP/MP),and attempts to show an alternative model of the beginning of the Japanese Upper Paleolithic.This paper suggests several possible specimens of LP/MP and recommends further geoarchaeological investigation to understand the reliability and cultural relationship between possible LP/MP specimens and the Early Upper Paleolithic(EUP).The start of the Japanese EUP is presently characterized by a flake industry with trapezoids and denticulates around 39-37 kaBP cal on Paleo-Honshu Island,which has partial resemblance with contemporary assemblages in China and the Korean Peninsula,although trapezoids are endemic only to the Japanese EUP and may have derived from the ancestral lithic tradition.Blade technology appeared earliest on Central Paleo-Honshu Island,about 1000 years later than the earliest flake technology.Although blade technology may have originated from the elongated flake technology of the previous period,the sudden simultaneous emergence implies that it diffused from the Korean Peninsula.This paper proposes that blade technology from the Korean Peninsula arrived on the northeastern Paleo-Honshu Island,including the Japan Sea coastal region of western Honshu,rather than the southwest,where flake technology long prospered,due to differences in ecological settings and adaptation strategies between the two regions. 展开更多
关键词 japanese Archipelago Early Upper Paleolithic migration route TRAPEZOID denticulate blade technology
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Does social information affect the settlement decisions of resident birds in their second breeding attempt?A case study of the Japanese Tit(Parus minor)
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作者 Xudong Li Jiangping Yu +5 位作者 Dake Yin Longru Jin Keqin Zhang Li Shen Zheng Han Haitao Wang 《Avian Research》 SCIE CSCD 2024年第3期326-335,共10页
Individuals may gather information about environmental conditions when deciding where to breed in order to maximize their lifetime fitness.They can obtain social information by observing conspecifics and heterospecifi... Individuals may gather information about environmental conditions when deciding where to breed in order to maximize their lifetime fitness.They can obtain social information by observing conspecifics and heterospecifics with similar ecological needs.Many studies have shown that birds can rely on social information to select their nest sites.The location of active nests and the reproductive success of conspecifics and heterospecifics can provide accurate predictions about the quality of the breeding habitat.Some short-lived species can facultatively reproduce two and/or more times within a breeding season.However,few studies have focused on how multiplebrooding individuals select nest sites for their second breeding attempts.In this study,we use long-term data to test whether the Japanese Tit(Parus minor)can use social information from conspecifics and/or heterospecifics(the Eurasian Nuthatch Sitta europaea,the Daurian Redstart Phoenicurus auroreus and the Yellow-rumped Flycatcher Ficedula zanthopygia)to select a nest site for the second breeding attempt.Our results showed that the nest boxes occupied by tits on their second breeding attempt tended to be surrounded by more breeding conspecific nests,successful first nests of conspecifics,and fewer failed first nests of conspecifics than the nest boxes that remained unoccupied(the control group).However,the numbers of breeding heterospecific nests,successful heterospecific nests,and failed heterospecific nests did not differ between the nest boxes occupied by tits on their second breeding attempt and the unoccupied nest boxes.Furthermore,the tits with local successful breeding experience tended to choose areas with more successful first nests of conspecifics than those without successful breeding experience.Thus,we suggest that conspecifics'but not heterospecifics'social information within the same breeding season is the major factor influencing the nest site selection of Japanese Tits during second breeding attempts. 展开更多
关键词 Conepeific Heterospecifie japanese tits Multiple brooding Nest-site selection Public infomation Social information
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Serological Investigation into the Infected Genotypes of Patients with Japanese Encephalitis in the Coastal Provinces of China
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作者 Weijia Zhang Jierong Zhao +10 位作者 Qikai Yin Shenghui Liu Ruichen Wang Shihong Fu Fan Li Ying He Kai Nie Guodong Liang Songtao Xu Guang Yang Huanyu Wang 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第7期716-725,共10页
Objective Genotypes(G)1,3,and 5 of the Japanese encephalitis virus(JEV)have been isolated in China,but the dominant genotype circulating in Chinese coastal areas remains unknown.We searched for G5 JEV-infected cases a... Objective Genotypes(G)1,3,and 5 of the Japanese encephalitis virus(JEV)have been isolated in China,but the dominant genotype circulating in Chinese coastal areas remains unknown.We searched for G5 JEV-infected cases and attempted to elucidate which JEV genotype was most closely related to human Japanese encephalitis(JE)in the coastal provinces of China.Methods In this study,we collected serum specimens from patients with JE in three coastal provinces of China(Guangdong,Zhejiang,and Shandong)from 2018 to 2020 and conducted JEV cross-neutralization tests against G1,G3,and G5.Results Acute serum specimens from clinically reported JE cases were obtained for laboratory confirmation from hospitals in Shandong(92 patients),Zhejiang(192 patients),and Guangdong(77 patients),China,from 2018 to 2020.Seventy of the 361 serum specimens were laboratory-confirmed to be infected with JEV.Two cases were confirmed to be infected with G1 JEV,32 with G3 JEV,and two with G5 JEV.Conclusion G3 was the primary infection genotype among JE cases with a definite infection genotype,and the infection caused by G5 JEV was confirmed serologically in China. 展开更多
关键词 japanese encephalitis virus Serological investigation Plaque reduction neutralization test Cross-neutralization test GENOTYPE
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Japanese Sign Language Recognition by Combining Joint Skeleton-Based Handcrafted and Pixel-Based Deep Learning Features with Machine Learning Classification
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作者 Jungpil Shin Md.Al Mehedi Hasan +2 位作者 Abu Saleh Musa Miah Kota Suzuki Koki Hirooka 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第6期2605-2625,共21页
Sign language recognition is vital for enhancing communication accessibility among the Deaf and hard-of-hearing communities.In Japan,approximately 360,000 individualswith hearing and speech disabilities rely on Japane... Sign language recognition is vital for enhancing communication accessibility among the Deaf and hard-of-hearing communities.In Japan,approximately 360,000 individualswith hearing and speech disabilities rely on Japanese Sign Language(JSL)for communication.However,existing JSL recognition systems have faced significant performance limitations due to inherent complexities.In response to these challenges,we present a novel JSL recognition system that employs a strategic fusion approach,combining joint skeleton-based handcrafted features and pixel-based deep learning features.Our system incorporates two distinct streams:the first stream extracts crucial handcrafted features,emphasizing the capture of hand and body movements within JSL gestures.Simultaneously,a deep learning-based transfer learning stream captures hierarchical representations of JSL gestures in the second stream.Then,we concatenated the critical information of the first stream and the hierarchy of the second stream features to produce the multiple levels of the fusion features,aiming to create a comprehensive representation of the JSL gestures.After reducing the dimensionality of the feature,a feature selection approach and a kernel-based support vector machine(SVM)were used for the classification.To assess the effectiveness of our approach,we conducted extensive experiments on our Lab JSL dataset and a publicly available Arabic sign language(ArSL)dataset.Our results unequivocally demonstrate that our fusion approach significantly enhances JSL recognition accuracy and robustness compared to individual feature sets or traditional recognition methods. 展开更多
关键词 japanese Sign Language(JSL) hand gesture recognition geometric feature distance feature angle feature GoogleNet
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Vice-President Liu Hongcai Meets the Japanese Okinawa Peace and Friendship Delegation
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《International Understanding》 2024年第1期31-31,共1页
On December 29th,CAFIU Vice-President Liu Hongcai met with the Japanese Okinawa Peace and Friendship Delegation to exchange views on the relationship and people-to-people exchanges between China and Japan.Vice-Preside... On December 29th,CAFIU Vice-President Liu Hongcai met with the Japanese Okinawa Peace and Friendship Delegation to exchange views on the relationship and people-to-people exchanges between China and Japan.Vice-President Liu Hongcai said that Okinawa-ken and China are geographically close and culturally connected,and both sides share a long history of friendly exchanges. 展开更多
关键词 PEACE FRIENDSHIP japanese
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What is the Real Situation of the Japanese Cosmetics Market?
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作者 Yang Xiaofeng 《China Detergent & Cosmetics》 CAS 2024年第2期26-29,共4页
The Japanese cosmetics market still deserves major focus when talking about the cosmetics development.First of all,in terms of purchasing power,Japan is the third largest cosmetics consumer in the world with huge mark... The Japanese cosmetics market still deserves major focus when talking about the cosmetics development.First of all,in terms of purchasing power,Japan is the third largest cosmetics consumer in the world with huge market potential,only after the United States and China;secondly,in terms of scientific research and technology,Japan has always been at the forefront of the cosmetics R&D in the world,leading the direction of many cosmetics categories.Especially in Asia,the Japanese cosmetics market has long played a pioneering role in the industry.In the post-pandemic era,what changes have taken place in the Japanese cosmetics market after the severe impact of COVID-19?And what are the new trends? 展开更多
关键词 MARKET MARKET japanese
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Japanese candlestick charts for diabetes
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作者 Diana Boj-Carceller 《World Journal of Methodology》 2024年第2期167-171,共5页
Continuous glucose monitoring(CGM)is a popular technology among the diabetic population,especially in patients with type 1 diabetes and those with type 2 diabetes treated with insulin.The American Diabetes Association... Continuous glucose monitoring(CGM)is a popular technology among the diabetic population,especially in patients with type 1 diabetes and those with type 2 diabetes treated with insulin.The American Diabetes Association recommends standardization of CGM reports with visual cues,such as the ambulatory glucose profile.Nevertheless,interpreting this report requires training and time for CGM to be cost-efficient.In this work it has been proposed to incorporate Japanese candlestick charts in glucose monitoring.These graphs are used in price analysis in financial markets and are easier to view.Each candle provides extra information to make prudent decisions since it reports the opening,maximum,minimum and closing glucose levels of the chosen time frame,usually the daily one.The Japanese candlestick chart is an interesting tool to be considered in glucose control.This graphic representation allows identification of glucose trends easily through the colors of the candles and maximum and minimum glucose values. 展开更多
关键词 japanese candlestick chart Candlestick chart Ambulatory glucose profile Glucose monitoring Continuous glucose monitoring HYPOGLYCEMIA
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有机合成化学中新的构件——Japanese试剂 被引量:2
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作者 骆焱平 何良年 李凯 《化学试剂》 CAS CSCD 2000年第5期289-290,共2页
介绍了 Japanese试剂的制备、结构和化学反应。并就 Japanese试剂在有机合成中的应用加以概述。
关键词 japanese试剂 氧-硫交换反应 环化反应 合成
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Japanese试剂的合成新方法 被引量:1
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作者 骆焱平 郑服丛 何良 《化学试剂》 CAS CSCD 北大核心 2001年第5期289-289,314,共2页
用二甲苯作溶剂来代替 1 ,2 ,4 -三氯苯使五硫化二磷和硫酚反应 ,制得的 Japanese试剂产率由 5 8%提高到 72 %
关键词 japanese试剂 合成 氧硫交换试剂 2 4-双(苯基硫基)-1 3-二硫-2 4-二磷杂环丁烷-2 4-二硫化物
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Characteristics of natural Japanese yew population in Muling Nature Reserve of Heilongjiang Province,China 被引量:1
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作者 刘彤 周志强 《Journal of Forestry Research》 SCIE CAS CSCD 2006年第2期132-134,共3页
The scalar of Japanese yew (Taxus cuspidata) population and the relationship between individual distribution and site factors were analyzed according to investigating data in 74 sample belts with a total sampled are... The scalar of Japanese yew (Taxus cuspidata) population and the relationship between individual distribution and site factors were analyzed according to investigating data in 74 sample belts with a total sampled area of 436.872 hm2 in Muling Nature Reserve. The result showed that the distribution rules of Japanese yew population were correlated to elevation, slope position, slope aspect and slope gradient. The optimal distribution range in elevation for the natural Japanese yew population is at the attitudes of 700-800 m. The amounts of Japanese yew individuals on shady slope were more than those on sunny slope. On top slope and mid-slope, the individual amounts of Japanese yew are more than those on toe slope. Most of Japanese yew individuals occurred on slope gradient of less than 15. The scalar of the population was decreased with the slope gradient increasing. 展开更多
关键词 japanese yew Taxus cuspidate Muling Nature Reserve POPULATION
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Prevention and Cure of Acute Alcohol Intoxication in Mice by Administration of Compound of Japanese Raisintree Fruit, Lobed Kudzuvine Flower Bud and Lightyellow Sophora Root 被引量:2
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作者 孔玲 李杰 张秀珍 《Agricultural Science & Technology》 CAS 2014年第5期874-876,881,共4页
[Objective] We aimed to investigate the preventive and therapeutical effect of compound of traditional Chinese drugs (Japanese raisintree fruit, lobed kudzuvine flower bud and lightyel ow sophora root) on acute alc... [Objective] We aimed to investigate the preventive and therapeutical effect of compound of traditional Chinese drugs (Japanese raisintree fruit, lobed kudzuvine flower bud and lightyel ow sophora root) on acute alcohol intoxication in mice. [Method] Acute alcohol intoxication was induced by administering alcohol to mice. Three different doses (low, middle and high) of compound of traditional Chinese drugs were administered to mice before and after administering alcohol respectively to investigate the preventive and therapeutical effect of drugs on acute alcohol intox-ication through doing statistical analysis about drunk mice and their sleeping time. The concentration of malondialdehyde (MDA), reduced glutathione (GSH) and triglyc-erides (TG) in liver was also determined to investigate the protective effect of drugs on liver. [Result] The efficacy of compound of traditional Chinese drugs on acute al-cohol intoxication was dose-dependent. High-dose administration decreased the number of drunk mice significantly compared with control group; middle- and high-dose administration reduced the sleeping time of drunk mice and the concentration of MDA and TG in liver tissue; three doses al increased the concentration of GSH. [Conclusion] The compound of Japanese raisintree fruit, lobed kudzuvine flower bud and lightyel ow sophora root had preventive and therapeutical effect on hangover, and it also had certain preventive and therapeutical effect on liver damage caused by alcohol. 展开更多
关键词 japanese raisintree fruit Lobed kudzuvine flower bud Lightyel ow sophora root Acute alcohol intoxication Anti-drunk Sobering effect
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Japanese试剂的环化反应(英文)
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作者 骆焱平 郑服丛 何良年 《合成化学》 CAS CSCD 2003年第6期467-468,共2页
利用Japanese试剂与含活泼氢的双官能团化合物的环化反应 ,合成了含N -P -N ,N -P-O的五元磷杂环化合物 ,并用IR ,NMR和MS对新化合物进行了表征。
关键词 japanese试剂 环化反应 磷杂环
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Yoji Sasaki's New Japanese Garden
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作者 余佳 陈展川 《Journal of Landscape Research》 2010年第11期28-30,36,共4页
The paper analyzed the design concept and design method of Yoji Sasaki and appreciated his representative works,aiming to provide reference and enlightenment for inheritance and development of Chinese classical gardens.
关键词 Yoji Sasaki NEW japanese GARDEN IDEA
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The contrast between Chinese and Japanese culture and language From the sociolinguistics point of view Introduction
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作者 刘英 《大众商务(下半月)》 2009年第3期147-149,共3页
关键词 高等教育 日本人 中国人 文化 语言学
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Factors associated with incomplete colonoscopy at a Japanese academic hospital 被引量:7
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作者 Shigeo Koido Toshifumi Ohkusa +9 位作者 Kosaburo Nakae Tetsuji Yokoyama Tomoyoshi Shibuya Naoto Sakamoto Kan Uchiyama Hiroshi Arakawa Taro Osada Akihito Nagahara Sumio Watanabe Hisao Tajiri 《World Journal of Gastroenterology》 SCIE CAS 2014年第22期6961-6967,共7页
AIM: To evaluate significant risk factors for incomplete colonoscopy at a Japanese academic hospital.
关键词 COLONOSCOPY INCOMPLETE Intubation rates japanese academic hospital Risk factors Inflammatory bowel disease
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Differences in the behavior characteristics between Daphnia magna and Japanese madaka in an on-line biomonitoring system 被引量:7
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作者 Zongming Ren Zijian Wang 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2010年第5期703-708,共6页
It is important to select suitable organisms to adapt the requirement of different environment monitoring purposes.Following our previous study,the behavioral responses of Daphnia magna and Japanese madaka (Oryzias l... It is important to select suitable organisms to adapt the requirement of different environment monitoring purposes.Following our previous study,the behavioral responses of Daphnia magna and Japanese madaka (Oryzias latipes) were investigated and compared under flow-through conditions in an on-line biomonitoring system.The results showed that both D.magna and Japanese madaka had similar biological clock,but the circadian rhythms of Japanese madaka was more clearly recorded than that of D.magna.And the sensitivity of D.magna was about two orders of magnitudes higher than that of Japanese madaka in different types of toxic chemicals (dichlorovos,deltamethrin and cadmium chloride).However,when both animals were used in an on-line biomonitoring system,the life span of D.magna was less than 7 days and Japanese madaka could last for more than one month without feeding.Therefore,D.magna was proposed to be a more sensitive bioindicator and was suitable for short term monitoring the pollution events at concentration level closing to the water quality standard,while Japanese madaka was more suitable for the long-term monitoring for accidental discharges. 展开更多
关键词 Daphnia magna japanese madaka on-line biomonitoring behavioral responses
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Mechanism of Japanese encephalitis virus genotypes replacement based on human,porcine and mosquito-originated cell lines model 被引量:6
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作者 Loan Phuong Do Trang Minh Bui Nga Thi Phan 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2016年第4期325-328,共4页
Objective:To examine the multiplication efficiency Japanese encephalitis virus(JEV)genotype Ⅰ(G Ⅰ) and genotype Ⅲ(GⅢ) of different cell lines which originated from human,porcine,mosquitoes in order to prove mechan... Objective:To examine the multiplication efficiency Japanese encephalitis virus(JEV)genotype Ⅰ(G Ⅰ) and genotype Ⅲ(GⅢ) of different cell lines which originated from human,porcine,mosquitoes in order to prove mechanism of JEV G Ⅰ replacement JEV GⅢ since it emerging in nature recent decades.Methods:The mixture of Gi and GⅢ JEV isolates was inoculated on human rhabdomyosarcoma(RD).pig kidney epithelial(PS) and Aedes albopictus C6/36 clone(C6/36) which originated from human,porcine and mosquitoes,respectively.Plaque assays were performed to calculate virus titer and real-time RT-PCR with GⅠand GⅢspecific primer sets to quantify the number of GⅠ and GUI RNA copies.Results:The highest virus titer reached at the 3rd day of post infection when G Ⅰand GⅢ mixture was inoculated on RD and PS and that of C636 was at the 4^(th)day.JEVs were amplified and maintained by C6/36 cells after 10 passages whereas that by RD and PS only limited within 8 and 6 passages,respectively.GⅠ strain amplified and maintained more efficiently on C6/36 and PS but not RD.whereas GⅢ strain amplified and maintained more efficiently on RD.Conclusions:There is a correlation between the multiplication efficiency of GⅠ and GⅢ JEV strains when these two genotype strains co-infected on different cell lines with the predominance of GⅠstrains in C6/36 and PS and the limited detection of G 1 strains in RD cells proving a possible mechanism of shift JEV genotypes in nature recent decades since GⅠ emerging. 展开更多
关键词 japanese ENCEPHALITIS virus GENOTYPE I GENOTYPE MULTIPLICATION Shift GENOTYPE
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TaqMan Real-time RT-PCR Assay for Detecting and Differentiating Japanese Encephalitis Virus 被引量:13
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作者 SHAO Nan LI Fan +8 位作者 NIE Kai FU Shi Hong ZHANG Wei Jia HE Ying LEI Wen Wen WANG Qian Ying LIANG Guo Dong CAO Yu Xi WANG Huan Yu 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2018年第3期208-214,共7页
Objective To detect Japanese encephalitis virus(JEV) rapidly and distinguish its genotypes, a TaqMan-based reverse transcriptase quantitative polymerase chain reaction(RT-PCR) detection system was developed.Method... Objective To detect Japanese encephalitis virus(JEV) rapidly and distinguish its genotypes, a TaqMan-based reverse transcriptase quantitative polymerase chain reaction(RT-PCR) detection system was developed.Methods By aligning the full-length sequences of JEV(G1-G5), six sets of highly specific TaqMan real-time RT-PCR primers and probes were designed based on the highly conserved NS1, NS2, and M genes of JEV, which included one set for non-specific JEV detection and five sets for the detection of specific JEV genotypes. Twenty batches of mosquito samples were used to evaluate our quantitative PCR assay.Results With the specific assay, no other flavivirus were detected. The lower limits of detection of the system were 1 pfu/mL for JEV titers and 100 RNA copies/μL. The coefficients of variation of this real-time RT-PCR were all 〈 2.8%. The amplification efficiency of this method was between 90% and 103%.Conclusion A TaqMan real-time RT-PCR detection system was successfully established to detect and differentiate all five JEV genotypes. 展开更多
关键词 japanese encephalitis virus GENOTYPE TaqMan real-time RT-PCR
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Molecular Characterization of Full-length Genome of Japanese Encephalitis Virus Genotype V Isolated from Tibet, China 被引量:8
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作者 LI Ming Hua FU Shi Hong +3 位作者 CHEN Wei Xin WANG Huan Yu CAO Yu Xi LIANG Guo Dong 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2014年第4期231-239,共9页
Objective To determine the molecular characterization of full-length genome of Japanese encephalitis virus (JEV) genotype V. Methods The full-length nucleotide sequences of JEV strains isolated from different locati... Objective To determine the molecular characterization of full-length genome of Japanese encephalitis virus (JEV) genotype V. Methods The full-length nucleotide sequences of JEV strains isolated from different locations and sources were used in sequence and phylogenetic analysis. Results The full-length genome of genotypes V JEV, XZ0934, and Muar strain were composed of 10 983 and 10 988 nucleotides respectively and shared a lower level of identity with JEV genotypes I-IV, ranging from 78.4% (G I, KV1899) to 79.7% (G III, JaGAr01), for the nucleotide sequences, and from 90.0%(G I, KV1899) to 91.8%(G III, JaGAr01) for the amino acid sequences. The open reading frame (ORF) of JEV genotype V spanned nucleotides 96 to 10 397 and encoded 3 433 amino acids. Interestingly, a comparison with JEV genotype I-IV revealed that 3 nucleotides (encoded with a serine residue) were inserted in the NS4A gene of JEV genotype V, and the insertion of nucleotides was also found in downstream of the ORF stop codon in 3’-untranslated region. Moreover, numerous amino acid mutations were observed in 3 functional domains of the E gene of JEV genotype V. Conclusion The molecular characterization of JEV genotype V is significantly different from that of the known genotypes I-IV. The mutations located in the coding region and the non-coding region may be molecular markers of JEV genotype V and warrant further studies to determine their effects on biology and immunogenicity of genotype V strains. 展开更多
关键词 japanese encephalitis virus Genotype V Molecular characterization
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