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The Making of a Health Profession:How Chinese Medicine Became a Nationally Registered Allied Health Profession in Australia
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作者 John L McDonald Judy B James 《Chinese Medicine and Culture》 2024年第1期51-62,共12页
In 2012, traditional Chinese medicine(TCM) practitioners in Australia became nationally-registered allied health professionals in three categories: acupuncturist, Chinese herbal medicine practitioner, and Chinese herb... In 2012, traditional Chinese medicine(TCM) practitioners in Australia became nationally-registered allied health professionals in three categories: acupuncturist, Chinese herbal medicine practitioner, and Chinese herbal medicine dispenser. Australia was the first Western country to introduce national registration for Chinese medicine, followed by Portugal and, recently, New Zealand. The practice of TCM in Australia can be traced back to the beginning of Chinese immigration to Australia during the Victorian Gold Rush which began in the 1850s. The process which led to national registration commenced in the early 1970s with the establishment of the first acupuncture courses. Decades of gradual development of courses from unaccredited part-time diplomas to accredited bachelor degrees, and the development, by the profession, of national consensus on educational standards were essential elements in the process which led to registration. Professional associations, such as the Australian Acupuncture and Chinese Medicine Association Ltd.(AACMA), also developed a framework of professional selfregulation, including Codes of Ethics, Codes of Conduct, ongoing professional development requirements and Infection Control Guidelines, and provided leadership in the development of the profession. After decades of tribalism and division within the TCM profession, the National Academic Standards Committee brought almost all stakeholders together to reach a consensus on the Australian Guidelines for Traditional Chinese Medicine Education which were published by AACMA in 2001. Professional associations also collaborated on joint submissions to the government in support of registration, which was introduced first in the state of Victoria in 2000, and subsequently became national in 2012. Despite national registration, some barriers still remain, and professional associations continue to lobby the federal government for inclusion in Medicare, chronic disease management scheme, and Veterans Affairs. 展开更多
关键词 aCUPUNCTURE chinese medicine REGisTRaTION Regulation Education Standards aUSTRaLIa TCM
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The Dissemination and Development of Chinese Medicine in Pakistan
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作者 LIN Jie Saeed Saboor 《Chinese Medicine and Culture》 2024年第2期160-166,共7页
The article focuses on the dissemination and development of Chinese medicine in Pakistan.Religious records show that Chinese medicine was introduced to Pakistan as early as 1,400 years ago,while Hijama(Chinese cupping... The article focuses on the dissemination and development of Chinese medicine in Pakistan.Religious records show that Chinese medicine was introduced to Pakistan as early as 1,400 years ago,while Hijama(Chinese cupping)was used by Prophet Hazrat Muhammad to cure different types of diseases.Exchanges and cooperations between China and Pakistan continue to the present day.Acupuncture and moxibustion therapy,cupping therapy and herbal medicine are practiced with significant merits in today’s Pakistan.In the future,with the proposal of the Belt and Road Initiative and the landmark project of China-Pakistan Economic Corridor,Chinese medicine can be strengthened through cooperations at the herbal medicine trade level,the research and development level,the educational level,and the social association level. 展开更多
关键词 Belt and Road Initiative chinese medicine COOPERaTION Development Pakistan
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Clinical Observation of the Hot and Humid Compress Therapy of Traditional Chinese Medicine in the Treatment of Qi Stagnation and Blood Stasis Type of Lumbar Disc Herniation
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作者 Hailin Song Kui Xu +3 位作者 Hong Zhu Zengwu Xu Peng Li Runkai Wang 《Open Journal of Orthopedics》 2024年第7期312-324,共13页
Background: Although a number of studies have reported that the hot and humid compress from traditional Chinese medicine (TCM) is effective in treating lumbar disc herniation (LDH) with qi stagnation and blood stasis,... Background: Although a number of studies have reported that the hot and humid compress from traditional Chinese medicine (TCM) is effective in treating lumbar disc herniation (LDH) with qi stagnation and blood stasis, clinical evidence is limited. Objective: The purpose of this study is to provide high-quality evidence to support the effectiveness of the traditional Chinese hot and humid compress in the treatment of LDH with qi stagnation and blood stasis. Methods: From October 2021 to November 2023, 86 patients with LDH of qi stagnation and blood stasis type were recruited in our hospital and divided into a control (n = 43) and an observation group (n = 43) according to the random number table method. The control group was given routine clinical treatment, and the observation group was treated with the hot and humid compress therapy for two weeks. The visual analogue scale (VAS) score, Japanese Orthopaedic Association (JOA) score, TCM syndrome score, serum interleukin-6 (IL-6), serum interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) were observed and compared between the two groups before and after treatment, and the clinical efficacy of the two groups was evaluated. Results: After treatment, the VAS score, TCM symptom score, and serum IL-6, IL-1β, and TNF-α levels decreased in both groups (P P P P P Conclusions: The hot and humid compress of traditional Chinese medicine can effectively relieve pain, restore lumbar function, improve TCM syndromes, reduce the level of inflammatory factors, and have a curative effect in treating LDH. 展开更多
关键词 chinese Medicine Hot and Humid Compress Lumbar Disc Herniation Qi Stagnation and Blood Stasis Type TCM Symptom Score Clinical Efficacy
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The Application of the Domestication and Foreignization Translation Strategies in the Context of the Dissemination of Chinese Culture:A Case Study of the English Translation of Long
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作者 Xueming Li 《Journal of Educational Theory and Management》 2024年第2期16-19,共4页
In January 2024,the Chinese Year of the Loong,how to translate the Chinese character Long went viral on the Internet.Taking the English translation of Long as an example,this study tends to make a tentative analysis o... In January 2024,the Chinese Year of the Loong,how to translate the Chinese character Long went viral on the Internet.Taking the English translation of Long as an example,this study tends to make a tentative analysis of the application of translation strategies in the macro context of the dissemination of Chinese culture.Moreover,it probes into the phenomenon of Chinese cultural aphasia by analyzing the domestication and foreignization of Long in three aspects.The three attitudes provided ought to be addressed in the Chinese-English translations.This study emphasizes enhancing translators’cultural awareness and their cultural confidence in the process of translating the source language to the target language. 展开更多
关键词 DOMESTICaTION FOREIGNIZaTION chinese Culture Cultural Confidence
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An Introduction to the Dissemination of Chinese Culture in English Teaching in Colleges and Universities
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作者 Hui Fang 《Journal of Contemporary Educational Research》 2024年第1期116-120,共5页
Language and culture are closely related,and understanding the cultural knowledge embedded in the process of language learning is an important goal of English teaching in colleges and universities.At present,the disse... Language and culture are closely related,and understanding the cultural knowledge embedded in the process of language learning is an important goal of English teaching in colleges and universities.At present,the dissemination of Chinese culture in English teaching in colleges and universities is lacking,which affects the improvement of students’intercultural communication skills.In order to effectively solve such problems,we need to take effective measures to disseminate Chinese culture by combining teaching content and students’characteristics.This paper summarizes the problems of Chinese culture dissemination in English teaching in colleges and universities,and explores effective countermeasures and teaching considerations,hoping to provide teachers with valuable guidelines. 展开更多
关键词 Colleges and universities English teaching chinese culture
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Research on Localized English Education for Transnational Left-behind Children in the Context of English Global Localization: A Case Study of Wenzhou Overseas Chinese Hometown
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作者 Yujie Su Xueyan Li +4 位作者 Huili Ma Shuchang Dong Ruoruo Lin Lijuan Zou Qiaoqiao Lin 《教育技术与创新》 2024年第1期36-49,共14页
With the increasing development of English globalization,the trend of combining English with local cultures has become more evident.This research focuses on five schools in the Wenzhou overseas Chinese hometown to inv... With the increasing development of English globalization,the trend of combining English with local cultures has become more evident.This research focuses on five schools in the Wenzhou overseas Chinese hometown to investigate the current status of English education from the perspectives of teachers,students,and textbooks.The aim was to propose bilingual education strategies for the education of transnational left-behind children(TLC).By examining the situation of English education in this specific context,this study sought to address the unique challenges faced by TLC and provide effective educational approaches.Interviews,observations,and document analysis were employed to gather data by means of questionnaire research methods.The findings of this study settled on the improvement of bilingual education for TLC and insights into enhancing English education in multicultural settings. 展开更多
关键词 GLOCaLIZaTION transnational left-behind children(TLC) bilingual education Wenzhou Overseas chinese Hometown
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Five commonly used traditional Chinese medicine formulas in the treatment of ulcerative colitis:A network meta-analysis 被引量:2
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作者 Zhi-Hui Zhao Yi-Hang Dong +5 位作者 Xin-Qi Jiang Jing Wang Wan-Li Qin Zhang-Yi Liu Xiao-Qing Zhang Yu-Jie Wei 《World Journal of Clinical Cases》 SCIE 2024年第22期5067-5082,共16页
BACKGROUND Currently,traditional Chinese medicine(TCM)formulas are commonly being used as adjunctive therapy for ulcerative colitis in China.Network meta-analysis,a quantitative and comprehensive analytical method,can... BACKGROUND Currently,traditional Chinese medicine(TCM)formulas are commonly being used as adjunctive therapy for ulcerative colitis in China.Network meta-analysis,a quantitative and comprehensive analytical method,can systematically compare the effects of different adjunctive treatment options for ulcerative colitis,providing scientific evidence for clinical decision-making.AIM To evaluate the clinical efficacy and safety of commonly used TCM for the treatment of ulcerative colitis(UC)in clinical practice through a network metaanalysis.METHODS Clinical randomized controlled trials of these TCM formulas used for the adjuvant treatment of UC were searched from the establishment of the databases to July 1,2022.Studies that met the inclusion criteria were screened and evaluated for literature quality and risk of bias according to the Cochrane 5.1 standard.The methodological quality of the studies was assessed using ReviewManager(RevMan)5.4,and a funnel plot was constructed to test for publication bias.ADDIS 1.16 statistical software was used to perform statistical analysis of the treatment measures and derive the network relationship and ranking diagrams of the various intervention measures.RESULTS A total of 64 randomized controlled trials involving 5456 patients with UC were included in this study.The adjuvant treatment of UC using five TCM formulations was able to improve the clinical outcome of the patients.Adjuvant treatment with Baitouweng decoction(BTWT)showed a significant effect[mean difference=36.22,95%confidence interval(CI):7.63 to 65.76].For the reduction of tumor necrosis factor in patients with UC,adjunctive therapy with BTWT(mean difference=−9.55,95%CI:−17.89 to−1.41),Shenlingbaizhu powder[SLBZS;odds ratio(OR)=0.19,95%CI:0.08 to 0.39],and Shaoyao decoction(OR=−23.02,95%CI:−33.64 to−13.14)was effective.Shaoyao decoction was more effective than BTWT(OR=0.12,95%CI:0.03 to 0.39),SLBZS(OR=0.19,95%CI:0.08 to 0.39),and Xi Lei powder(OR=0.34,95%CI:0.13 to 0.81)in reducing tumor necrosis factor and the recurrence rate of UC.CONCLUSION TCM combined with mesalazine is more effective than mesalazine alone in the treatment of UC. 展开更多
关键词 Network meta-analysis Traditional chinese medicine Ulcerative colitis MESaLaZINE TREaTMENT
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Synergistic effects of carbon cycle metabolism and photosynthesis in Chinese cabbage under salt stress 被引量:1
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作者 Hao Liang Qiling Shi +8 位作者 Xing Li Peipei Gao Daling Feng Xiaomeng Zhang Yin Lu Jingsen Yan Shuxing Shen Jianjun Zhao Wei Ma 《Horticultural Plant Journal》 SCIE CAS CSCD 2024年第2期461-472,共12页
Chinese cabbage(Brassica rapa ssp. pekinensis) has a long cultivation history and is one of the vegetable crops with the largest cultivation area in China. However, salt stress severely damages photosynthesis and horm... Chinese cabbage(Brassica rapa ssp. pekinensis) has a long cultivation history and is one of the vegetable crops with the largest cultivation area in China. However, salt stress severely damages photosynthesis and hormone metabolism, nutritional balances, and results in ion toxicity in plants. To better understand the mechanisms of salt-induced growth inhibition in Chinese cabbage, RNA-seq and physiological index determination were conducted to explore the impacts of salt stress on carbon cycle metabolism and photosynthesis in Chinese cabbage. Here, we found that the number of thylakoids and grana lamellae and the content of starch granules and chlorophyll in the leaves of Chinese cabbage under salt stress showed a time-dependent response, first increasing and then decreasing. Chinese cabbage increased the transcript levels of genes related to the photosynthetic apparatus and carbon metabolism under salt stress, probably in an attempt to alleviate damage to the photosynthetic system and enhance CO_(2) fixation and energy metabolism. The transcription of genes related to starch and sucrose synthesis and degradation were also enhanced;this might have been an attempt to maintain intracellular osmotic pressure by increasing soluble sugar concentrations. Soluble sugars could also be used as potential reactive oxygen species(ROS) scavengers, in concert with peroxidase(POD)enzymes, to eliminate ROS that accumulate during metabolic processes. Our study characterizes the synergistic response network of carbon metabolism and photosynthesis under salt stress. 展开更多
关键词 chinese cabbage Salt stress Carbon metabolism PHOTOSYNtheSis CHLOROPLaST
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Thoroughly Study and Implement a Holistic Approach to National Security to Safeguard Chinese Modernization
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作者 《Contemporary International Relations》 2024年第5期4-25,共22页
2024 marks the tenth anniversary of a holistic approach to national security. As an important component of Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era, a holistic approach to national se... 2024 marks the tenth anniversary of a holistic approach to national security. As an important component of Xi Jinping Thought on Socialism with Chinese Characteristics for a New Era, a holistic approach to national security provides fundamental guidance for China's national security work in the new era and is, therefore, of great theoretical and practical significance. This approach has several distinct features: it ref lects the trends of our times, is deeply rooted in China's national culture, and follows a people-centered, struggle-oriented, systematic, st rategic, in novative, and practice-based approach. By upholding and developing a holistic approach to national security, the Central Committee of the Communist Party of China(CPC) has comprehensively strengthened the Party's absolute leadership over national security, reshaped the systems and mechanisms for national security across the board, and made brilliant achievements in national security work in the new era. Given the context of the momentous changes unseen in a century that shape today's world, the national security situation facing China is increasingly complex and grim, characterized by many challenges and new characteristics. On the new journey toward rejuvenating the nation and building China into a strong country, we should fully implement the spirit of the 20th CPC National Congress, firmly pursue a holistic approach to national security, and accelerate the modernization of China's national security system and capacity to ensure steady and sustained progress in Chinese modernization. 展开更多
关键词 chinese modernization holistic approach to national security national security situation
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Research progress of traditional Chinese medicine in the treatment of endocrine metabolic diseases in 2023
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作者 Ming-Yao Fan Jing Ru +6 位作者 Si Wang Yan Chen Xiao-Xia Zhang Guo-Long Li Qing-Shan Hai Wei-Bo Wen Huan-Tian Cui 《Traditional Medicine Research》 2024年第12期51-65,共15页
This study aimed to provide a comprehensive review of the research progress in Chinese medicine in the treatment of endocrine metabolic diseases in 2023,covering traditional Chinese medicine(TCM)monomers,TCM extracts,... This study aimed to provide a comprehensive review of the research progress in Chinese medicine in the treatment of endocrine metabolic diseases in 2023,covering traditional Chinese medicine(TCM)monomers,TCM extracts,and TCM combinations,including non-alcoholic fatty liver disease,type 2 diabetes mellitus and its complications,obesity,hyperuricaemia,and thyroid disorders.After systematic sorting and summary,we found that in 2023,the research focusing on the application of TCM for endocrine metabolic diseases was still on the mechanism of action at the cellular and molecular levels,which not only influenced the classical pathways of lipid metabolism,but also delved into the key mechanisms of anti-inflammation,anti-oxidation,anti-insulin resistance,and so on.Additionally,TCM has shown remarkable results in the treatment of endocrine metabolic diseases by improving intestinal flora disorders and abnormal cellular iron death.These research results provide valuable ideas,methods,and tools for TCM in the prevention and treatment of endocrine metabolic diseases,and provide important references and guidance for future research and practice. 展开更多
关键词 endocrine metabolic diseases traditional chinese medicine chinese medicine extracts chinese medicine compound therapeutic mechanism
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Effect of Modified Biochar with Organic Fertiliser on the Growth and Development of Chinese Rose
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作者 Liyuan Mu Hongyin Zhou +4 位作者 Junlei Wang Sijing Sun Haichan Yang Naiming Zhang Li Bao 《Advances in Bioscience and Biotechnology》 CAS 2024年第6期344-359,共16页
In order to reduce the waste of resources and environmental pollution caused by excessive application of chemical fertilizers, improve the utilization rate of fertilizers, and promote the large-scale and high-quality ... In order to reduce the waste of resources and environmental pollution caused by excessive application of chemical fertilizers, improve the utilization rate of fertilizers, and promote the large-scale and high-quality development of the Chinese rose industry. In this experiment, corn stover biochar, phosphoric acid modified biochar and organic fertilizer were used as test materials, and the effects of mixed application of modified biochar and organic fertilizer on the growth and development of Chinese rose as well as soil physicochemical properties were investigated by using the method of pot planting test. The results showed that modified biochar with organic fertilizer had the most significant effect on the enhancement of soil pH, organic matter content and soil carbon-to-nitrogen ratio. After 120 d of planting, modified biochar with organic fertilizer had the most significant effect on the enhancement of plant height and crown width of Chinese rose;both organic fertilizer and modified biochar with organic fertilizer significantly increased the chlorophyll content of Chinese rose. The number of flowers and the number of branches were the highest in the modified biochar with organic fertilizer treatment. In conclusion, the application of modified biochar with organic fertilizer can better improve the soil pH, and increase the soil organic matter content and carbon-to-nitrogen ratio to change the biological traits of Chinese rose. The results of this study provide a theoretical basis for the reduction of chemical fertilizers and the resource utilization of agricultural wastes and guarantee the sustainable development of the cut flower industry. 展开更多
关键词 BIOCHaR Modified Biochar chinese Rose Organic Fertiliser
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Molecular mechanism and research progress of traditional Chinese medicine in the treatment of prostate cancer
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作者 Hai-Luo Wang Ruo-Ran Zhang +7 位作者 Hao Wang Peng Xu Jing-Kai Wang Bo Chen Hao Xu Deng Pan Yu-Yang Ma Kun Pang 《Traditional Medicine Research》 2025年第1期62-72,共11页
Prostate cancer(PCa)is one of the most common malignant tumors in the male genitourinary system,ranking second in incidence worldwide.Traditional Chinese medicine(TCM),as an important component of complementary and al... Prostate cancer(PCa)is one of the most common malignant tumors in the male genitourinary system,ranking second in incidence worldwide.Traditional Chinese medicine(TCM),as an important component of complementary and alternative medicine,shows unique advantages in cancer treatment.Chinese herbal medicine is usually composed of multiple ingredients and involves multiple signaling pathways,which showed function of inducing apoptosis of cancer cells,arresting the cell cycle,inhibiting invasion and metastasis,reducing drug resistance,and regulating immune function.Physical therapy is also an important treatment of TCM.Currently,Physical therapy such as acupuncture or Tai Chi and Qigong are gaining increased recognition in the management of PCa,particularly in addressing issues like urinary incontinence and bone metastasis-related pain.This article reviews the TCM treatment and therapy of PCa,in order to provide new research avenues and treatment options for the treatment of PCa with TCM and improve the quality of life of patients. 展开更多
关键词 traditional chinese medicine prostate cancer chinese herbal medicine physical therapy
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On the Relationship between Chinese Language Education in Malaysia and Indonesia with Their National Conditions
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作者 Limao Chen 《Open Journal of Applied Sciences》 2024年第8期2169-2175,共7页
Chinese language education exists in both Malaysia and Indonesia. The commonalities and individualities of the national conditions of both countries have an impact on their Chinese language education. The official lan... Chinese language education exists in both Malaysia and Indonesia. The commonalities and individualities of the national conditions of both countries have an impact on their Chinese language education. The official languages scripts, and major beliefs of the two countries are quite similar, and under their influence, local Chinese have special expectations for Chinese language education. Compared to Indonesia, Malaysian Chinese have a larger proportion of the population and a tendency towards marriage, which to some extent is more conducive to the Chinese language education of local Chinese. Both countries’ national conditions and personalities have unfavorable factors for local Chinese language education. 展开更多
关键词 MaLaYSIa Indonesia chinese Language Education national Conditions
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Characterisation of Human-Wildlife Conflicts around the Kahuzi-Biega National Park, Eastern Democratic Republic of Congo
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作者 Basubi Muke Matthieu Vwima Stany +3 位作者 Ayagirwe Basengere Rodrigue Mushagalusa Freddy Benjamin-Fink Nicole Bobo Kadiri Serge 《Journal of Environmental Protection》 2024年第3期343-356,共14页
The history of mankind contains so many illustrations of well-classified and violent struggles against various animals over crop production in agricultural fields, attacks on human life or competition in order to have... The history of mankind contains so many illustrations of well-classified and violent struggles against various animals over crop production in agricultural fields, attacks on human life or competition in order to have access to certain natural resources. The aim of this study is to characterise the human-wildlife conflicts that occur around the KBNP, especially with regard to primates. Surveys were carried out in 260 households selected using the snowball method. The results showed that human-wildlife conflicts around the KBNP are characterised by the destruction of crops in riparian fields by monkeys, chimpanzees and gorillas, the destruction of houses, physical attacks and zoonoses. Despite the conservation and protection measures for wildlife and local populations put in place by the Park’s managers, conflicts between local populations and the Park’s wild animals are still visible. These conflicts lead to the detention of wild animals by local people roaming in the villages and to poaching on the Park’s boundaries. The weakness of the community management policy on the part of the park managers and the resentment of the indigenous peoples towards the restriction of their access to natural resources are the major constraints on the sustainable management of conflicts between the local populations and the wild animals in the KBNP. The strategies for the sustainable resolution of human-wildlife conflicts around the KBNP must be geared towards and integrated into a community conservation approach. 展开更多
关键词 Community Conservation Human-Wildlife Conflict Kahuzi-Biega national Park
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Mechanism of traditional Chinese medicine in the treatment of psoriasis with depression:A review
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作者 ZHANG Ning YANG Su-qing YUAN Rui 《Journal of Hainan Medical University》 CAS 2024年第1期76-82,共7页
Psoriasis is a kind of immune-mediated, chronic, inflammatory skin disease, which is often associated with different degrees of psychological disorders. Specifically, there is a significant correlation between psorias... Psoriasis is a kind of immune-mediated, chronic, inflammatory skin disease, which is often associated with different degrees of psychological disorders. Specifically, there is a significant correlation between psoriasis and depression, and they show the relationships of reciprocal causation and mutual promotion. Psoriasis with depression is more harmful than simple psoriasis, and its prognosis is worse, which brings a huge burden to the family and society and is worthy of clinical attention. Based on the pathogenic factors of western medicine and pathogenesis of traditional Chinese medicine in psoriasis with depression, the paper summarized and elaborated the research progress on the mechanism of traditional Chinese medicine in the treatment of psoriasis with depression, in order to provide new ideas for clinical treatment. 展开更多
关键词 PSORIaSis DEPRESSION Mechanism of action chinese medicinal compound Characteristic therapy of traditional chinese medicine
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Tetramethylpyrazine and paeoniflorin combination(TMP-PF)alleviates atherosclerosis progress by reducing hyperlipemia and inhibiting plaque angiogenesis via the NR4A1/VEGFR2 pathway
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作者 Rong Yuan Qiqi Xin +8 位作者 Weili Shi Yu Miao Zhengchuan Zhu Yahui Yuan Ying Chen Xiaoning Chen Sean Xiao Leng Keji Chen Weihong Cong 《Food Science and Human Wellness》 SCIE CAS CSCD 2024年第5期2642-2652,共11页
Atherosclerosis remains a great threat to human health worldwide.Previous studies found that tetramethylpyrazine(TMP)and paeonifl orin(PF)combination(TMP-PF)exerts anti-atherosclerotic effects in vitro.However,whether... Atherosclerosis remains a great threat to human health worldwide.Previous studies found that tetramethylpyrazine(TMP)and paeonifl orin(PF)combination(TMP-PF)exerts anti-atherosclerotic effects in vitro.However,whether TMP-PF improves atherosclerosis in vivo needs further exploration.The present study aims to assess the anti-atherosclerotic properties of TMP-PF in ApoE^(-/-)mice and explore the related molecule mechanisms.Results showed that TMP and high-dose TMP-PF decreased serum triglyceride and low-density lipoprotein cholesterol levels,suppressed vascular endothelial growth factor receptor 2(VEGFR2)and nuclear receptor subfamily 4 group A member 1(NR4A1)expression in aortic tissues,inhibited plaque angiogenesis,reduced plaque areas,and alleviated atherosclerosis in ApoE^(-/-)mice.Also,TMP-PF exhibited a better modulation effect than TMP or PF alone.However,NR4A1 agonist abolished the anti-atherosclerotic effects of TMP-PF.In conclusion,TMP-PF was first found to alleviate atherosclerosis progression by reducing hyperlipemia and inhibiting plaque angiogenesis via the NR4A1/VEGFR2 pathway,indicating that TMP-PF had a positive effect on reducing hyperlipemia and attenuating atherosclerosis development. 展开更多
关键词 atheROSCLEROSis HYPERLIPEMIa aNGIOGENESis Plaque stability chinese medicine TETRaMETHYLPYRaZINE PaEONIFLORIN
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The potential of Chinese herbal medicines in treating anxiety disorders
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作者 Jia-Qi Xie Jian-Mei Huang Can Wang 《Integrative Medicine Discovery》 2024年第5期1-5,共5页
In recent years,there has not been much progress in developing anxiolytic drugs.Amongst the barriers are the lack of clarity on the pathogenesis of anxiety disorders,low product conversion rates for developing drugs t... In recent years,there has not been much progress in developing anxiolytic drugs.Amongst the barriers are the lack of clarity on the pathogenesis of anxiety disorders,low product conversion rates for developing drugs targeting the receptors,and species variability.Some scientists have focused on natural medicines,especially herbal medicines in traditional Chinese medicine.New drugs with excellent anxiolytic activity are hoped to be found in herbal medicines with anxiolytic effects.This mini-review summarised three Chinese herbal medicines with anxiolytic effects and anxiolytic herbal formulas used in the traditional Chinese medicine clinic.Several key issues that block the development of new anxiolytic drugs are also discussed.We hope to provide some ideas for researching and developing new anxiolytic drugs and studying anxiolytic components in traditional Chinese medicine. 展开更多
关键词 traditional chinese medicine anxiolytic drugs chinese herbal medicines
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Systems Theory-Driven Framework for AI Integration into the Holistic Material Basis Research of Traditional Chinese Medicine
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作者 Jingqi Zeng Xiaobin Jia 《Engineering》 SCIE EI CAS CSCD 2024年第9期28-50,共23页
This paper introduces a systems theory-driven framework to integration artificial intelligence(AI)into traditional Chinese medicine(TCM)research,enhancing the understanding of TCM’s holistic material basis while adhe... This paper introduces a systems theory-driven framework to integration artificial intelligence(AI)into traditional Chinese medicine(TCM)research,enhancing the understanding of TCM’s holistic material basis while adhering to evidence-based principles.Utilizing the System Function Decoding Model(SFDM),the research progresses through define,quantify,infer,and validate phases to systematically explore TCM’s material basis.It employs a dual analytical approach that combines top-down,systems theory-guided perspectives with bottom-up,elements-structure-function methodologies,provides comprehensive insights into TCM’s holistic material basis.Moreover,the research examines AI’s role in quantitative assessment and predictive analysis of TCM’s material components,proposing two specific AIdriven technical applications.This interdisciplinary effort underscores AI’s potential to enhance our understanding of TCM’s holistic material basis and establishes a foundation for future research at the intersection of traditional wisdom and modern technology. 展开更多
关键词 artificial intelligence Systems theory Traditional chinese medicine Material basis BOTTOM-UP
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A chromosome-level genome assembly for Chinese plum‘Wushancuili'reveals the molecular basis of its fruit color and susceptibility to rain-cracking
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作者 Kun Zhou Jingwen Wang +8 位作者 Lin Pan Fang Xiang Yi Zhou Wei Xiong Ming Zeng Donald Grierson Wenbin Kong Lingyu Hu Wanpeng Xi 《Horticultural Plant Journal》 SCIE CAS CSCD 2024年第3期672-688,共17页
Chinese plum(Prunus salicina Lindl.)originates from China and makes a large contribution to the global production of plums.The P.salicina‘Wushancuili'has a green coloration and high fruit quality and is economica... Chinese plum(Prunus salicina Lindl.)originates from China and makes a large contribution to the global production of plums.The P.salicina‘Wushancuili'has a green coloration and high fruit quality and is economically important in eliminating poverty and protecting ecology in the Yangtze River Three Gorges Reservoir.However,rain-induced cracking(rain-cracking,literally skin cracking caused by rain)is a limitation to‘Wushancuili'fruit production and causes severe losses.This study reported a high-quality‘Wushancuili'genome assembly consisting of a 302.17-Mb sequence with eight pseudo-chromosomes and a contig N50 of 23.59 Mb through the combination of Illumina sequencing,Pacific Biosciences HiFiⅢsequencing,and high-throughput chromosome conformation capture technology.A total of 25109 protein-coding genes are predicted and 54.17%of the genome is composed of repetitive sequences.‘Wushancuili'underwent a remarkable orthoselection during evolution.Gene identification revealed that loss-of-function in four core MYB10 genes results in the anthocyanin deficiency and absence of red color,revealing the green coloration due to the residual high chlorophyll in fruit skin.Besides,the occurrence of cracking is assumed to be closely associated with cell wall modification and frequently rain-induced pathogen enrichment through transcriptomic analysis.The loss of MYB10 genes might render fruit more susceptible to pathogen-mediated cracking by weakening the epidermal strength and reactive oxygen species(ROS)scavenging.Our findings provided fundamental knowledge regarding fruit coloration and rain-cracking and will facilitate genetic improvement and cultivation management in Chinese plums. 展开更多
关键词 chinese plum Fruit coloration Fruit epidermis Genome MYB10 Rain-cracking
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Fine mapping and cloning of the sterility gene Bra2Ms in nonheading Chinese cabbage(Brassica rapa ssp.chinensis)
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作者 Liping Song Xia Li +8 位作者 Liguang Tang Chuying Yu Bincai Wang Changbin Gao Yanfeng Xie Xueli Zhang Junliang Wang Chufa Lin Aihua Wang 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第4期1195-1204,共10页
The application of a male-sterile line is an ideal approach for hybrid seed production in non-heading Chinese cabbage(Brassica rapa ssp.chinensis).However,the molecular mechanisms underlying male sterility in B.rapa a... The application of a male-sterile line is an ideal approach for hybrid seed production in non-heading Chinese cabbage(Brassica rapa ssp.chinensis).However,the molecular mechanisms underlying male sterility in B.rapa are still largely unclear.We previously obtained the natural male sterile line WS24-3 of non-heading Chinese cabbage and located the male sterile locus,Bra2Ms,on the A2 chromosome.Cytological observations revealed that the male sterility of WS24-3 resulted from disruption of the meiosis process during pollen formation.Fine mapping of Bra2Ms delimited the locus within a physical distance of about 129 kb on the A2 chromosome of B.rapa.The Bra039753 gene encodes a plant homeodomain(PHD)-finger protein and is considered a potential candidate gene for Bra2Ms.Bra039753 was significantly downregulated in sterile line WS24-3 compared to the fertile line at the meiotic anther stage.Sequence analysis of Bra039753 identified a 369 bp fragment insertion in the first exon in male sterile plants,which led to an amino acid insertion in the Bra039753 protein.In addition,the 369 bp fragment insertion was found to cosegregate with the male sterility trait.This study identified a novel locus related to male sterility in non-heading Chinese cabbage,and the molecular marker obtained in this study will be beneficial for the marker-assisted selection of excellent sterile lines in non-heading Chinese cabbage and other Brassica crops. 展开更多
关键词 non-heading chinese cabbage male sterility Bra2Ms fine mapping PHD-finger protein
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