[Objective] The aim was to evaluate the regional eco-environmental quality by using the universal index formula of parameterization combination operator based normalized index values.[Method] Through setting reference...[Objective] The aim was to evaluate the regional eco-environmental quality by using the universal index formula of parameterization combination operator based normalized index values.[Method] Through setting reference values and normalized transformation formulae for typical ecological environmental indexes appropriately,the difference among the standard normalized values would become very small after normalized transformation,and the ecological environmental indices expressed by normalized values can be equivalent to normalized indices.Under certain optimization conditions,shuffled frog leaping based on immune evolutionary particle swarm optimization algorithm was applied to optimize the parameters in parameterization combination operator formula,and the universal index formula suited to eco-environmental quality assessment was established finally.[Result] The universal index formula of parameterization combination operator,appropriate for any m(1≤m≤23) ecological environmental indices,was used to assess the eco-environmental quality of towns surrounding Headland Reservoir,and the results were in full accordance with those of unascertained measure method,that is,the eco-environmental quality of five towns around Headland Reservoir was the fourth grade.[Conclusion]The universal index formula of parameterization combination operator,suited to eco-environmental quality evaluation,is simple and intuitive in form,easy in computation and universal in application.展开更多
Dempster-Shafer(D-S)evidence theory is a key technology for integrating uncertain information from multiple sources.However,the combination rules can be paradoxical when the evidence seriously conflict with each other...Dempster-Shafer(D-S)evidence theory is a key technology for integrating uncertain information from multiple sources.However,the combination rules can be paradoxical when the evidence seriously conflict with each other.In the paper,we propose a novel combination algorithm based on unsupervised Density-Based Spatial Clustering of Applications with Noise(DBSCAN)density clustering.In the proposed mechanism,firstly,the original evidence sets are preprocessed by DBSCAN density clustering,and a successfully focal element similarity criteria is used to mine the potential information between the evidence,and make a correct measure of the conflict evidence.Then,two different discount factors are adopted to revise the original evidence sets,based on the result of DBSCAN density clustering.Finally,we conduct the information fusion for the revised evidence sets by D-S combination rules.Simulation results show that the proposed method can effectively solve the synthesis problem of high-conflict evidence,with better accuracy,stability and convergence speed.展开更多
目的:观察基于名中医经验的中医辨证组方对老年慢性肾炎(CKD1-3a期)患者的有效性和安全性。方法:将84例老年慢性肾炎患者随机分成治疗组(42例)和对照组(42例)。治疗组采用西医基础联合中医辨证组方治疗;对照组仅接受西医基础治疗,疗程均...目的:观察基于名中医经验的中医辨证组方对老年慢性肾炎(CKD1-3a期)患者的有效性和安全性。方法:将84例老年慢性肾炎患者随机分成治疗组(42例)和对照组(42例)。治疗组采用西医基础联合中医辨证组方治疗;对照组仅接受西医基础治疗,疗程均为24周。观察两组治疗前后24 h尿蛋白定量(24 h UPQ)、肾小球滤过率(eGFR)等临床指标变化,以及疗效和安全性。结果:与本组基线比较,两组治疗后12、18、24周24 h UPQ均显著下降(P<0.01),且24周时治疗组优于对照组(P<0.01)。治疗组总有效率为67.57%,对照组总有效率41.67%,治疗组显著高于对照组(P<0.05)。将慢性肾脏病(CKD)3a期患者进行亚组分析提示,24周后治疗组eGFR较本组基线及同期对照组显著升高(P<0.01,P<0.05),而对照组治疗前后无显著变化。治疗组不良反应发生4例,对照组2例,两组无严重不良反应出现。结论:基于名中医经验的中医辨证组方治疗老年慢性肾炎(CKD1-3a期),可减少尿蛋白,提高临床疗效,对其中的CKD3a期患者可能具有改善eGFR作用,且安全性较好。展开更多
目的探讨针刺联合疏肝化瘀方在慢性乙型重型肝炎(chronic severe hepatitis B,CSHB)治疗中的应用价值。方法选取100例慢性乙型重型肝炎患者,随机分为西医组、针刺组、中药组和联合组,每组25例。西医组予以常规西医治疗,于此基础上,针刺...目的探讨针刺联合疏肝化瘀方在慢性乙型重型肝炎(chronic severe hepatitis B,CSHB)治疗中的应用价值。方法选取100例慢性乙型重型肝炎患者,随机分为西医组、针刺组、中药组和联合组,每组25例。西医组予以常规西医治疗,于此基础上,针刺组予以针刺治疗,中药组予以疏肝化瘀方,联合组予以针刺联合疏肝化瘀方治疗。观察4组临床疗效与安全性,比较4组治疗前、治疗1个月后、治疗6个月后中医症候积分、肝功能指标[谷丙转氨酶(alanine aminotransferase,ALT)、谷草转氨酶(aspartate aminotransferase,AST)及γ-谷氨酰转肽酶(γ-glutamyl transpeptidase,GGT)]和T淋巴细胞亚群(CD^(4+)、CD^(8﹢)和CD^(4+)/CD^(8﹢))。结果联合组、中药组及针刺组总有效率均高于西医组(P<0.05);治疗1个月、6个月后,联合组、中药组及针刺组中医证候主症、次症积分及总积分低于西医组(P<0.05);治疗1个月、6个月后联合组ALT、AST、GGT水平及CD^(8﹢)低于中药组、针刺组和西医组,CD^(4+)及CD^(4+)/CD^(8﹢)高于中药组、针刺组、西医组(P<0.05);4组治疗期间均未出现不良反应。结论在西医常规治疗基础上,针刺联合疏肝化瘀方联合治疗CSHB可提高疗效,改善免疫功能与肝功能,缓解患者症状,且具有较高安全性。展开更多
[Objectives]The extraction conditions of formula oolong tea were investigated by an orthogonal experiment.[Methods]The technical conditions were optimized by the 4C method,and the application of formula oolong tea ext...[Objectives]The extraction conditions of formula oolong tea were investigated by an orthogonal experiment.[Methods]The technical conditions were optimized by the 4C method,and the application of formula oolong tea extract in cigarettes was studied.[Results]①In the experimental range,the best sensory evaluation effect of formula oolong tea extract was obtained with extraction conditions of 70%ethanol as extraction solvent,extraction time h,extraction temperature 25℃,and ultrasonic frequency 80 kHz,and follow-up low-temperature concentration,low-temperature sedimentation and low-temperature centrifugation.②The effects of different centrifugal speeds on the quality of formula oolong tea extract were explored.The formula oolong tea extract obtained under the conditions of 3000 r/min and centrifugal time of 10 min showed the best evaluation effect with soft and delicate smoke,rich smoke fragrance,good comfort and refreshing mouthfeel.③The effective aroma components in the formula oolong tea extract were qualitatively analyzed by GC-MS.[Conclusions]This study provides high-quality raw materials and a theoretical basis for the research of independent flavor blending in cigarette industry enterprises.展开更多
基金Supported by Groundwork Project of Science and Technology(2009IM020100)National Natural Science Foundation of China(50779042,50739002,41101542)
文摘[Objective] The aim was to evaluate the regional eco-environmental quality by using the universal index formula of parameterization combination operator based normalized index values.[Method] Through setting reference values and normalized transformation formulae for typical ecological environmental indexes appropriately,the difference among the standard normalized values would become very small after normalized transformation,and the ecological environmental indices expressed by normalized values can be equivalent to normalized indices.Under certain optimization conditions,shuffled frog leaping based on immune evolutionary particle swarm optimization algorithm was applied to optimize the parameters in parameterization combination operator formula,and the universal index formula suited to eco-environmental quality assessment was established finally.[Result] The universal index formula of parameterization combination operator,appropriate for any m(1≤m≤23) ecological environmental indices,was used to assess the eco-environmental quality of towns surrounding Headland Reservoir,and the results were in full accordance with those of unascertained measure method,that is,the eco-environmental quality of five towns around Headland Reservoir was the fourth grade.[Conclusion]The universal index formula of parameterization combination operator,suited to eco-environmental quality evaluation,is simple and intuitive in form,easy in computation and universal in application.
文摘Dempster-Shafer(D-S)evidence theory is a key technology for integrating uncertain information from multiple sources.However,the combination rules can be paradoxical when the evidence seriously conflict with each other.In the paper,we propose a novel combination algorithm based on unsupervised Density-Based Spatial Clustering of Applications with Noise(DBSCAN)density clustering.In the proposed mechanism,firstly,the original evidence sets are preprocessed by DBSCAN density clustering,and a successfully focal element similarity criteria is used to mine the potential information between the evidence,and make a correct measure of the conflict evidence.Then,two different discount factors are adopted to revise the original evidence sets,based on the result of DBSCAN density clustering.Finally,we conduct the information fusion for the revised evidence sets by D-S combination rules.Simulation results show that the proposed method can effectively solve the synthesis problem of high-conflict evidence,with better accuracy,stability and convergence speed.
文摘目的:观察基于名中医经验的中医辨证组方对老年慢性肾炎(CKD1-3a期)患者的有效性和安全性。方法:将84例老年慢性肾炎患者随机分成治疗组(42例)和对照组(42例)。治疗组采用西医基础联合中医辨证组方治疗;对照组仅接受西医基础治疗,疗程均为24周。观察两组治疗前后24 h尿蛋白定量(24 h UPQ)、肾小球滤过率(eGFR)等临床指标变化,以及疗效和安全性。结果:与本组基线比较,两组治疗后12、18、24周24 h UPQ均显著下降(P<0.01),且24周时治疗组优于对照组(P<0.01)。治疗组总有效率为67.57%,对照组总有效率41.67%,治疗组显著高于对照组(P<0.05)。将慢性肾脏病(CKD)3a期患者进行亚组分析提示,24周后治疗组eGFR较本组基线及同期对照组显著升高(P<0.01,P<0.05),而对照组治疗前后无显著变化。治疗组不良反应发生4例,对照组2例,两组无严重不良反应出现。结论:基于名中医经验的中医辨证组方治疗老年慢性肾炎(CKD1-3a期),可减少尿蛋白,提高临床疗效,对其中的CKD3a期患者可能具有改善eGFR作用,且安全性较好。
文摘[Objectives]The extraction conditions of formula oolong tea were investigated by an orthogonal experiment.[Methods]The technical conditions were optimized by the 4C method,and the application of formula oolong tea extract in cigarettes was studied.[Results]①In the experimental range,the best sensory evaluation effect of formula oolong tea extract was obtained with extraction conditions of 70%ethanol as extraction solvent,extraction time h,extraction temperature 25℃,and ultrasonic frequency 80 kHz,and follow-up low-temperature concentration,low-temperature sedimentation and low-temperature centrifugation.②The effects of different centrifugal speeds on the quality of formula oolong tea extract were explored.The formula oolong tea extract obtained under the conditions of 3000 r/min and centrifugal time of 10 min showed the best evaluation effect with soft and delicate smoke,rich smoke fragrance,good comfort and refreshing mouthfeel.③The effective aroma components in the formula oolong tea extract were qualitatively analyzed by GC-MS.[Conclusions]This study provides high-quality raw materials and a theoretical basis for the research of independent flavor blending in cigarette industry enterprises.