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Cascading Delays for the High-Speed Rail Network Under Different Emergencies:A Double Layer Network Approach
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作者 Xingtang Wu Mingkun Yang +3 位作者 Wenbo Lian Min Zhou Hongwei Wang Hairong Dong 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第10期2014-2025,共12页
High-speed rail(HSR) has formed a networked operational scale in China. Any internal or external disturbance may deviate trains’ operation from the planned schedules, resulting in primary delays or even cascading del... High-speed rail(HSR) has formed a networked operational scale in China. Any internal or external disturbance may deviate trains’ operation from the planned schedules, resulting in primary delays or even cascading delays on a network scale. Studying the delay propagation mechanism could help to improve the timetable resilience in the planning stage and realize cooperative rescheduling for dispatchers. To quickly and effectively predict the spatial-temporal range of cascading delays, this paper proposes a max-plus algebra based delay propagation model considering trains’ operation strategy and the systems’ constraints. A double-layer network based breadth-first search algorithm based on the constraint network and the timetable network is further proposed to solve the delay propagation process for different kinds of emergencies. The proposed model could deal with the delay propagation problem when emergencies occur in sections or stations and is suitable for static emergencies and dynamic emergencies. Case studies show that the proposed algorithm can significantly improve the computational efficiency of the large-scale HSR network. Moreover, the real operational data of China HSR is adopted to verify the proposed model, and the results show that the cascading delays can be timely and accurately inferred, and the delay propagation characteristics under three kinds of emergencies are unfolded. 展开更多
关键词 Delay propagation double layer network high speed rail network max-plus algebra
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Development of Strategic Industrial Clusters in Guangdong Higher Vocational Colleges based on the"Double High Plan" 被引量:1
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作者 Liping Yan Yanzhi Peng 《Journal of Contemporary Educational Research》 2021年第6期8-13,共6页
This article analyzed the ten strategic pillar industry clusters and the ten strategic emerging industry clusters which were confirmed and announced by Guangdong Province in May 2020 in addition to the 14 professional... This article analyzed the ten strategic pillar industry clusters and the ten strategic emerging industry clusters which were confirmed and announced by Guangdong Province in May 2020 in addition to the 14 professional groups of schools in Guangdong Province which were shortlisted in the"Double High Plan."With comparison and analysis,the degree of coincidence between the professional groups of higher vocational colleges and strategic industrial clusters in Guangdong Province which covered most of the industrial clusters was relatively high.The higher vocational colleges that were shortlisted in the"Double High Plan"still required dynamic adjustments in the construction of professional groups to achieve an allrounded integration of the supply of talents and industrial demands. 展开更多
关键词 double high plan Professional group Industrial clusters
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Plant Ideotype at Heading for Super High-Yielding Rice in Double-Cropping System in South China 被引量:3
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作者 CHEN You-ding WAN Bang-hui ZHANG Xu 《Rice science》 SCIE 2005年第2期92-100,共9页
The newly released super high-yielding hybrid rice combinations, Yueza 122, Fengyou 428, Peiza 67, and the super high-yielding conventional cultivars, Guangchao 3 and Shengtai 1, were grown in both early and late seas... The newly released super high-yielding hybrid rice combinations, Yueza 122, Fengyou 428, Peiza 67, and the super high-yielding conventional cultivars, Guangchao 3 and Shengtai 1, were grown in both early and late seasons. The morphological characters of each population were investigated at the heading stage, and the data were analyzed by using ANOVY and other statistic methods. The plant ideal morphological characters at the heading stage were established as follows: 1 ) for the early-season cropping, 90-105 cm plant height; 11-12 tillers per plant; 35-40 em length and 2.1-2.2 cm width of flag leaf; 46-50 cm length and 1.8-2.1 cm width of the second leaf from the top (L2); 59-64 cm length and 1.4-1.9 cm width of the third leaf from the top (L3); 7°-14°, 18° and 200-33° for the ideal leaf angles of the flag leaf, L2 and L3, respectively; 2) for the late-season cropping, 90-100 cm plant height; 9-15 tillers per plant; 30-41 cm length and 1.8-2.0 cm width of flag leaf; 53-61 cm length and 1.3-1.8 cm width of L2; 52-58 cm length and 1.2-1.5 cm width of L3; 9°-19°, 15°-37° and 16°-49° for the ideal leaf angles of the flag leaf, L2 and L3, respectively. The main physiological characteristics of these varieties were also analyzed. 展开更多
关键词 super high-yielding MORPHOLOGY IDEOTYPE heading stage South China double cropping rice
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Teaching Reform and Research on Art Design Majors in Higher Vocational Colleges under the Background of “Double High Plan”
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作者 Xin Zhang 《Journal of Contemporary Educational Research》 2021年第1期20-23,共4页
Training talents for the society is the responsibility of colleges and universities.The society needs applied and innovative art design majors.In order to cultivate talents needed by society and keep up with the devel... Training talents for the society is the responsibility of colleges and universities.The society needs applied and innovative art design majors.In order to cultivate talents needed by society and keep up with the development plan of the Ministry of Education,higher vocational colleges need to reform.This paper adopts the method of theoretical analysis to elaborate from the four aspects of focusing equally on science and education,promote learning by competition;integrating industry and education,nurturing talents together;keeping the mission in mind while serving students;and finding the right positioning,giving full play to the advantages. 展开更多
关键词 "double high plan" higher Vocational Colleges Art Design Major Teaching Reform
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Research on the Optimization of Talent Recruitment Process in Higher Vocational Colleges under the Background of Double High Plan
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作者 Litao Cui 《Proceedings of Business and Economic Studies》 2021年第1期18-21,共4页
In order to elucidate the relationship between talent recruitment and teacher allocation management in higher vocational colleges under the background of the"Double High Plan",this paper studies and analyzes... In order to elucidate the relationship between talent recruitment and teacher allocation management in higher vocational colleges under the background of the"Double High Plan",this paper studies and analyzes the current status of talent recruitment in Chinese higher vocational colleges in conjunction with the characteristics of talent resource allocation in higher vocational colleges and proposes to elucidate the priorities and improve supporting policies with reasonable planning to improve the optimization guideline of talent recruitment efficiency,so as to better accomplish the building of the national"double high plan"and improve the ability of higher vocational colleges to nurture more outstanding talents for the society. 展开更多
关键词 double high education plan higher vocational colleges Recruitment optimization
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Thoughts on the Management of Personnel Files in Higher Vocational Colleges in the Context of“Double High Plan”
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作者 Litao Cui 《Journal of Contemporary Educational Research》 2021年第3期19-22,共4页
Starting from the background of the"Double High Plan"in conjunction with the role of personnel file management in advancing the"Double High Plan",this paper analyzes the current status of personnel... Starting from the background of the"Double High Plan"in conjunction with the role of personnel file management in advancing the"Double High Plan",this paper analyzes the current status of personnel file management in higher vocational colleges and the necessity of personnel management in higher vocational colleges,and explores the effective measures to strengthen the informatization of personnel files management to make it more reasonable,standardized and informatized. 展开更多
关键词 double high plan Personnel File Management in higher Vocational Colleges Strategy Research
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Numerical simulation and control of welding distortion for double floor structure of high speed train 被引量:5
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作者 Wen-Chao Dong Shan-Ping Lu +3 位作者 Hao Lu Dian-Zhong Li Li-Jian Rong Yi-Yi Li 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2014年第6期849-859,共11页
The welding heat source models and the plastic tension zone sizes of a typical weld joint involved in the double floor structure of high speed train under different welding parameters were calculated by a thermal-elas... The welding heat source models and the plastic tension zone sizes of a typical weld joint involved in the double floor structure of high speed train under different welding parameters were calculated by a thermal-elastic-plastic FEM analysis based on SYSWELD code.Then,the welding distortion of floor structure was predicted using a linear elastic FEM and shrinkage method based on Weld Planner software.The effects of welding sequence,clamping configuration and reverse deformation on welding distortion of floor structure were examined numerically.The results indicate that the established elastic FEM model for floor structure is reliable for predicting the distribution of welding distortion in view of the good agreement between the calculated results and the measured distortion for real double floor structure.Compared with the welding sequence,the clamping configuration and the reverse deformation have a significant influence on the welding distortion of floor structure.In the case of30 mm reverse deformation,the maximum deformation can be reduced about 70%in comparison to an actual welding process. 展开更多
关键词 Welding distortion double floor welded structure high speed train Numerical simulation
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A Double Network Hydrogel with High Mechanical Strength and Shape Memory Properties 被引量:3
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作者 Lei Zhu Chun-ming Xiong +3 位作者 Xiao-fen Tang Li-jun Wang Kang Peng Hai-yang Yang 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2018年第3期350-358,368,共10页
Double network(DN)hydrogels as one kind of tough gels have attracted extensive at-tention for their potential applications in biomedical and load-bearing fields.Herein,we import more functions like shape memory into t... Double network(DN)hydrogels as one kind of tough gels have attracted extensive at-tention for their potential applications in biomedical and load-bearing fields.Herein,we import more functions like shape memory into the conventional tough DN hydro-gel system.We synthesize the PEG-PDAC/P(AAm-co-AAc)DN hydrogels,of which the first network is a well-defined PEG(polyethylene glycol)network loaded with PDAC(poly(acryloyloxyethyltrimethyl ammonium chloride))strands,while the second network is formed by copolymerizing AAm(acrylamide)with AAc(acrylic acid)and cross-linker MBAA(N;N′-methylenebisacrylamide).The PEG-PDAC/P(AAm-co-AAc)DN gels exhibits high mechanical strength.The fracture stress and toughness of the DN gels reach up to 0.9 MPa and 3.8 MJ/m^3,respectively.Compared with the conventional double network hydrogels with neutral polymers as the soft and ductile second network,the PEG-PDAC/P(AAm-co-AAc)DN hydrogels use P(AAm-co-AAc),a weak polyelectrolyte,as the second network.The AAc units serve as the coordination points with Fe^3+ions and physically crosslink the second network,which realizes the shape memory property activated by the reducing ability of ascorbic acid.Our results indicate that the high mechanical strength and shape memory properties,probably the two most important characters related to the potential application of the hydrogels,can be introduced simultaneously into the DN hydrogels if the functional monomer has been integrated into the network of DN hydrogels smartly. 展开更多
关键词 double NETWORK HYDROGEL WEAK POLYELECTROLYTE high mechanical strength Shape MEMORY properties
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Periodic Motion Planning and Control for Double Rotary Pendulum via Virtual Holonomic Constraints 被引量:1
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作者 Zeguo Wang Leonid B.Freidovich Honghua Zhang 《IEEE/CAA Journal of Automatica Sinica》 EI CSCD 2019年第1期291-298,共8页
Periodic motion planning for an under-actuated system is rather difficult due to differential dynamic constraints imposed by passive dynamics, and it becomes more difficult for a system with higher underactuation degr... Periodic motion planning for an under-actuated system is rather difficult due to differential dynamic constraints imposed by passive dynamics, and it becomes more difficult for a system with higher underactuation degree, that is with a higher difference between the number of degrees of freedom and the number of independent control inputs. However, from another point of view, these constraints also mean some relation between state variables and could be used in the motion planning.We consider a double rotary pendulum, which has an underactuation degree 2. A novel periodic motion planning is presented based on an optimization search. A necessary condition for existence of the whole periodic trajectory is given because of the higher underactuation degree of the system. Moreover this condition is given to make virtual holonomic constraint(VHC) based control design feasible. Therefore, an initial guess for the optimization of planning a feasible periodic motion is based on this necessary condition. Then, VHCs are used for the system transformation and transverse linearization is used to design a static state feedback controller with periodic matrix function gain. The controller gain is found through another optimization procedure. The effectiveness of initial guess and performance of the closed-loop system are illustrated through numerical simulations. 展开更多
关键词 double ROTARY PENDULUM periodic motion planning under-actuated mechanical systems VIRTUAL HOLONOMIC constraint (VHC)
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Double BP Q-Learning Algorithm for Local Path Planning of Mobile Robot 被引量:1
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作者 Guoming Liu Caihong Li +2 位作者 Tengteng Gao Yongdi Li Xiaopei He 《Journal of Computer and Communications》 2021年第6期138-157,共20页
Aiming at the dimension disaster problem, poor model generalization ability and deadlock problem in special obstacles environment caused by the increase of state information in the local path planning process of mobil... Aiming at the dimension disaster problem, poor model generalization ability and deadlock problem in special obstacles environment caused by the increase of state information in the local path planning process of mobile robot, this paper proposed a Double BP Q-learning algorithm based on the fusion of Double Q-learning algorithm and BP neural network. In order to solve the dimensional disaster problem, two BP neural network fitting value functions with the same network structure were used to replace the two <i>Q</i> value tables in Double Q-Learning algorithm to solve the problem that the <i>Q</i> value table cannot store excessive state information. By adding the mechanism of priority experience replay and using the parameter transfer to initialize the model parameters in different environments, it could accelerate the convergence rate of the algorithm, improve the learning efficiency and the generalization ability of the model. By designing specific action selection strategy in special environment, the deadlock state could be avoided and the mobile robot could reach the target point. Finally, the designed Double BP Q-learning algorithm was simulated and verified, and the probability of mobile robot reaching the target point in the parameter update process was compared with the Double Q-learning algorithm under the same condition of the planned path length. The results showed that the model trained by the improved Double BP Q-learning algorithm had a higher success rate in finding the optimal or sub-optimal path in the dense discrete environment, besides, it had stronger model generalization ability, fewer redundant sections, and could reach the target point without entering the deadlock zone in the special obstacles environment. 展开更多
关键词 Mobile Robot Local Path planning double BP Q-Learning BP Neural Network Transfer Learning
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Double North Pacific High in Summer 被引量:2
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作者 Kern E. Kenyon 《Natural Science》 2016年第5期220-226,共7页
An example of sea level pressure (SLP) and sea surface temperature (SST) is displayed for a summer month based on historical monthly mean data for the North Pacific. A double North Pacific High (NPH) co-occurred with ... An example of sea level pressure (SLP) and sea surface temperature (SST) is displayed for a summer month based on historical monthly mean data for the North Pacific. A double North Pacific High (NPH) co-occurred with a double large-scale SST maximum along 40 N. Centers of the two NPHs had very nearly the same longitudes as did the SST maxima. Seven similar coincidences happened within the 30-year records. These particular associations between extrema of SLPs and SSTs enhance a previously published conjecture that single and double NPHs are caused by heat transfer from the sea surface to the atmosphere. The eastern SST maximum is the signature of a permanent wide warm surface current flowing northeast off California. To the west of it in the summer is a transient wide warm surge of surface water flowing north as it crosses mid-latitudes. These are the heat sources that generate the single and double NPHs. 展开更多
关键词 double North Pacific high double SST Maxima
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Enhancement of Breakdown Voltage in AlGaN/GaN High Electron Mobility Transistors Using Double Buried p-Type Layers 被引量:1
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作者 罗俊 赵胜雷 +3 位作者 林志宇 张进成 马晓华 郝跃 《Chinese Physics Letters》 SCIE CAS CSCD 2016年第6期121-124,共4页
A novel A1GaN/GaN high electron mobility transistor (HEMT) with double buried p-type layers (DBPLs) in the GaN buffer layer and its mechanism are studied. The DBPL A1GaN/GaN HEMT is characterized by two equi-long ... A novel A1GaN/GaN high electron mobility transistor (HEMT) with double buried p-type layers (DBPLs) in the GaN buffer layer and its mechanism are studied. The DBPL A1GaN/GaN HEMT is characterized by two equi-long p-type GaN layers which are buried in the GaN buffer layer under the source side. Under the condition of high-voltage blocking state, two reverse p-n junctions introduced by the buried p-type layers will effectively modulate the surface and bulk electric fields. Meanwhile, the buffer leakage is well suppressed in this structure and both lead to a high breakdown voltage. The simulations show that the breakdown voltage of the DBPL structure can reach above 2000 V from 467 V of the conventional structure with the same gate-drain length of 8μm. 展开更多
关键词 AlGaN on is Enhancement of Breakdown Voltage in AlGaN/GaN high Electron Mobility Transistors Using double Buried p-Type Layers HEMT of in
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High-Performance Aqueous Zinc–Manganese Battery with Reversible Mn^(2+)/Mn^(4+) Double Redox Achieved by Carbon Coated MnO_x Nanoparticles 被引量:1
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作者 Jingdong Huang Jing Zeng +2 位作者 Kunjie Zhu Ruizhi Zhang Jun Liu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2020年第9期44-55,共12页
There is an urgent need for low-cost,high-energy-density,environmentally friendly energy storage devices to fulfill the rapidly increasing need for electrical energy storage.Multi-electron redox is considerably crucia... There is an urgent need for low-cost,high-energy-density,environmentally friendly energy storage devices to fulfill the rapidly increasing need for electrical energy storage.Multi-electron redox is considerably crucial for the development of high-energy-density cathodes.Here we present highperformance aqueous zinc-manganese batteries with reversible Mn2+/Mn4+ double redox.The active Mn4+is generated in situ from the Mn2+-containing MnOx nanoparticles and electrolyte.Benefitting from the low crystallinity of the birnessite-type MnO2 as well as the electrolyte with Mn2+additive,the MnOX cathode achieves an ultrahigh energy density with a peak of845.1 Wh kg-1 and an ultralong lifespan of 1500 cycles.The combination of electrochemical measurements and material characterization reveals the reversible Mn2+/Mn4+double redox(birnessite-type MnO2? monoclinic MnOOH and spinel ZnMn2O4 H?Mn2+ions).The reversible Mn2+/Mn4+double redox electrode reaction mechanism offers new opportunities for the design of low-cost,high-energy-density cathodes for advanced rechargeable aqueous batteries. 展开更多
关键词 Aqueous zinc–manganese batteries Mn-based cathode materials high energy density Mn2+/Mn4+double redox
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High-pressure synthesis, characterization, and equation of state of double perovskite Sr_2CoFeO_6
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作者 潘跃武 朱品文 王欣 《Chinese Physics B》 SCIE EI CAS CSCD 2015年第1期489-492,共4页
Double perovskite oxide Sr2 Co Fe O6(SCFO) has been obtained using a high-pressure and high-temperature(HPHT)synthesis method. Valence states of Fe and Co and their distributions in SCFO were examined with X-ray p... Double perovskite oxide Sr2 Co Fe O6(SCFO) has been obtained using a high-pressure and high-temperature(HPHT)synthesis method. Valence states of Fe and Co and their distributions in SCFO were examined with X-ray photoelectron spectroscopy. The electric transport behavior of SCFO showed a semiconductor behavior that can be well described by Mott's law for variable-range hopping conduction. The structural stability of SCFO was investigated at pressures up to 31 GPa with no pressure-induced phase transition found. Bulk modulus B0 was determined to be 163(2) GPa by fitting the pressure–volume data to the Birch–Murnaghan equation of state. 展开更多
关键词 double perovskite oxide electric properties high pressure
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Extreme Light Concentration and High Absorption of the Double Cylindrical Microcavities
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作者 衡航 王嵘 《Chinese Physics Letters》 SCIE CAS CSCD 2016年第8期49-53,共5页
We numerically study the enhancement factor of energy density and absorption efficiency inside the double cylindrical microcavities based on a triple-band metamaterial absorber. The compact single unit cell consists o... We numerically study the enhancement factor of energy density and absorption efficiency inside the double cylindrical microcavities based on a triple-band metamaterial absorber. The compact single unit cell consists of concentric gold rings with a gold disk in the center and a metallic ground plane separated by a dielectric layer. We demonstrate that the multilayer structure with subwavelength electromagnetic confinement allows 104-105-fold enhancement of the electromagnetic energy density inside the double cavities and contains the most energy of the incoming light. Particularly, the enhancement factor of energy density G shows strong ability of localizing light and some regularity as the change of the thickness of the dielectric slab and dielectric constant. At the normal incidence of electromagnetic radiation, the obtained reflection spectra show that the resonance frequencies of the double microcavities operate in the range of 10-30μm. We also calculate the absorption efficiency C, which can reach 95%, 97% and 95% at corresponding frequency by optimizing the structure's geometry parameters. Moreover, the proposed structure will be insensitive to the polarization of the incident wave due to the symmetry of the double cylindrical microcavities. The proposed optical metamaterial is a promising candidate as absorbing elements in scientific and technical applications due to its extreme confinement, multiband absorption and polarization insensitivity. 展开更多
关键词 in is on of Extreme Light Concentration and high Absorption of the double Cylindrical Microcavities been Figure
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Numerical simulation for 2D double-diffusive convection(DDC) in rectangular enclosures based on a high resolution upwind compact streamfunction model Ⅰ: numerical method and code validation
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作者 Yaping YAN Shuang WU +1 位作者 Kaiyuan TIAN Zhenfu TIAN 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2022年第9期1431-1448,共18页
A high resolution upwind compact streamfunction numerical algorithm for two-dimensional(2D)double-diffusive convection(DDC)is developed.The unsteady Navier-Stokes(N-S)equations in the streamfunction-velocity form and ... A high resolution upwind compact streamfunction numerical algorithm for two-dimensional(2D)double-diffusive convection(DDC)is developed.The unsteady Navier-Stokes(N-S)equations in the streamfunction-velocity form and the scalar temperature and concentration equations are used.An optimized third-order upwind compact(UCD3 opt)scheme with a low dispersion error for the first derivatives is utilized to approximate the third derivatives of the streamfunction in the advection terms of the N-S equations and the first derivatives in the advection terms of the scalar temperature and concentration equations.The remaining first derivatives of the streamfunction(velocity),temperature,and concentration variables used in the governing equations are discretized by the fourth-order compact Pade(SCD4)schemes.With the temperature and concentration variables and their approximate values of the first derivatives obtained by the SCD4 schemes,the explicit fourth-order compact schemes are suggested to approximate the second derivatives of temperature and concentration in the diffusion terms of the energy and concentration equations.The discretization of the temporal term is executed with the second-order Crank-Nicolson(C-N)scheme.To assess the spatial behavior capability of the established numerical algorithm and verify the developed computer code,the DDC flow is numerically solved.The obtained results agree well with the benchmark solutions and some accurate results available in the literature,verifying the accuracy,effectiveness,and robustness of the provided algorithm.Finally,a preliminary application of the proposed method to the DDC is carried out. 展开更多
关键词 double diffusive convection(DDC) high resolution heat and mass transfer upwind compact difference streamfunction formulation
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Research on Innovation of Modern Apprenticeship Talent Training Model for Art and Design Majors in Higher Vocational Education under the Background of "Double High"
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作者 Lu Zhang 《Journal of Contemporary Educational Research》 2021年第1期31-34,共4页
In order to cultivate more excellent talents in art and design majors following the requirements of the"13th Five-Year Plan"national education development,this paper analyzes in-depth on the current status o... In order to cultivate more excellent talents in art and design majors following the requirements of the"13th Five-Year Plan"national education development,this paper analyzes in-depth on the current status of higher vocational education in art design profession under the background of the"Double High"plan and the challenges faced,and proposes the building of school-enterprise"Double Subject"education system and the establishment of a"diversified"evaluation system.Deepening the integration of industry and education,schools and enterprises jointly explore modern apprenticeship talent training models for innovative art and design majors,and provide a strong guarantee for the implementation of the"Double High"plan modern apprenticeship talent training model. 展开更多
关键词 "double high"plan Art Design Profession Modern Apprenticeship System Talent Training
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DOUBLE HIGH ORDER S-BREAKING BIFURCATION POINTS AND THEIR NUMERICAL DETERMINATION
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作者 杨忠华 叶瑞松 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 1996年第7期633-646,共14页
We consider double high order S-breaking bifurcation points of two-Parameter dependent nonlinear problems with Z_2×Z_2-symmetry. Because of the underlying symmetry we could propose some regular extended systems... We consider double high order S-breaking bifurcation points of two-Parameter dependent nonlinear problems with Z_2×Z_2-symmetry. Because of the underlying symmetry we could propose some regular extended systems to determine double high order S-breaking bifurcation points. and we could also show that there exist two quadratic pitchfork bifurcation point paths passing through the point being considered. 展开更多
关键词 Z_2× Z_2-symmetry. double high order S-breaking bifurcation point. extended system
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Treatable focal region modulated by double excitation signal superimposition to realize platform temperature distribution during transcranial brain tumor therapy with high-intensity focused ultrasound 被引量:2
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作者 常诗卉 曹睿 +4 位作者 张亚斌 王佩国 吴世敬 钱宇晗 菅喜岐 《Chinese Physics B》 SCIE EI CAS CSCD 2018年第7期585-594,共10页
Recently, the phase compensation technique has allowed the ultrasound to propagate through the skull and focus into the brain. However, the temperature evolution during treatment is hard to control to achieve effectiv... Recently, the phase compensation technique has allowed the ultrasound to propagate through the skull and focus into the brain. However, the temperature evolution during treatment is hard to control to achieve effective treatment and avoid over-high temperature. Proposed in this paper is a method to modulate the temperature distribution in the focal region. It superimposes two signals which focus on two preset different targets with a certain distance. Then the temperature distribution is modulated by changing triggering time delay and amplitudes of the two signals. The simulation model is established based on an 82-element transducer and computed tomography (CT) data of a volunteer's head. A finite- difference time-domain (FDTD) method is used to calculate the temperature distributions. The results show that when the distances between the two targets respectively are 7.5-12.5 mm on the acoustic axis and 2.0-3.0 mm in the direction perpendicular to the acoustic axis, a focal region with a uniform temperature distribution (64-65 ℃) can be created. Moreover, the volume of the focal region formed by one irradiation can be adjusted (26.8-266.7 mm3) along with the uniform temperature distribution. This method may ensure the safety and efficacy of HIFU brain tumor therapy. 展开更多
关键词 high-intensity focused ultrasound (HIFU) transcranial therapy double excitation signal superim- position temperature modulation of focal region
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ASYMMETRIC SYNTHESIS Ⅻ:HIGHLY ENANTIOSELECTIVE SYNTHESIS OF α-AMINO ACIDS BY ALKYLATION OF THE KETIMINE FROM 2-HYDROXY-PINAN-3-ONE AND MENTHYL GLYCIN-ATE A DOUBLE ASYMMETRIC INDUCTION SYSTEM
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作者 Ai Qiao MI Zeng Xin MA Lan Jun WU Yao Zhong JIANG Chengdu Institute of Organic Chemistry,Academia Sinica,Chengdu 610015 《Chinese Chemical Letters》 SCIE CAS CSCD 1991年第2期115-118,共4页
A series of α-amino acids are obtained in 72-96% optical yields by alkylation of the ketimine derived from(+)-2-hydroxy-pinan-3-one and(-)-menthyl glycinate fol- lowed by hydrolysis of the alkylated intermediates wit... A series of α-amino acids are obtained in 72-96% optical yields by alkylation of the ketimine derived from(+)-2-hydroxy-pinan-3-one and(-)-menthyl glycinate fol- lowed by hydrolysis of the alkylated intermediates with mineral acid.The double asymmetric induction are explained by the transition model of lithium enolate. 展开更多
关键词 THF AMINO ACIDS BY ALKYLATION OF THE KETIMINE FROM 2-HYDROXY-PINAN-3-ONE AND MENTHYL GLYCIN-ATE A double ASYMMETRIC INDUCTION SYSTEM ASYMMETRIC SYNTHESIS highLY ENANTIOSELECTIVE SYNTHESIS OF ATE
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