Air temperature and photoperiod play an important role in the seedling development for tropical forest species.Both variables are sensitive to climate,and so evaluating thermal and photoperiodic effects on seedling de...Air temperature and photoperiod play an important role in the seedling development for tropical forest species.Both variables are sensitive to climate,and so evaluating thermal and photoperiodic effects on seedling development is fundamental,especially for climate change studies.Methods to quantify thermal time and the energy required for plants to reach a development stage include air temperature and cardinal temperatures.The photoperiod will also affect physiological reactions of a plant and thus its development.Here we evaluated the six thermal time methods widely used to compute thermal requirement,and identified the influence of the photoperiod from the 2015 and2016 growing seasons and 12 sowing dates in Itajubá,Minas Gerais state,Brazil,on seedling development of three native tropical forest species Psidium guajava L.(Myrtaceae),Citharexylum myrianthum Cham.(Verbenaceae),and Bixa orellana L.(Bixaceae).The method used to quantify thermal time influenced the analytical results of seedling development;the one that considered three cardinal temperatures and compared them with the mean air temperature(Method5)performed better in computing thermal requirements.The influence of photoperiod on seedling development was inconclusive for the three species,but all three developed better in mild temperatures(between 13.3℃and 26.9℃)with a photoperiod shorter than 13 h.展开更多
Taking the development of the times as the background,the historical evolution of modern architecture is combed from the perspective of the initial stage of industrialization to post-industrialization and then to the ...Taking the development of the times as the background,the historical evolution of modern architecture is combed from the perspective of the initial stage of industrialization to post-industrialization and then to the information age.It can be seen that there is a close connection between development and modern architecture in the context of the times.With the advancement of science and technology,the construction of buildings has undergone varying degrees of changes due to aesthetics,materials,structure,humanities,and technology.Behind these changes are the results of the progress and development of social productivity.While changing people’s social cognition,it also changes the development process of architecture.展开更多
China’s rural revitalization,which was initiated in the middle and late stages of modernization,features distinct characteristics of the times.It is necessary to approach rural revitalization in China from the aspect...China’s rural revitalization,which was initiated in the middle and late stages of modernization,features distinct characteristics of the times.It is necessary to approach rural revitalization in China from the aspects of industrial-agricultural coordination,urban-rural integration,and regional balance.Industrial-agricultural coordination concerns forging the“world’s factory”and,more importantly,developing into the“world’s farm”through rural revitalization.Urban-rural integration is not just about urban modernization,but also about rural modernization through rural revitalization.Regional balance requires the promotion of characteristic development in peripheral regions with targeted measures of rural revitalization,as well as the building of highly developed city clusters.展开更多
Marriage is a theme influenced by cultural progress. Economic factor is one of the main elements that people of the early nineteenth century considered when deciding a marriage. The pursuit of economic interest result...Marriage is a theme influenced by cultural progress. Economic factor is one of the main elements that people of the early nineteenth century considered when deciding a marriage. The pursuit of economic interest results in the advent of some tragic marriages while now it is a side reason. However, women today have made great advancement in education background, employment situation and social status. Women gradually have their economic ability, autonomy and social status. Hence, they began to lay emphasis on the equality and sense of happiness. This is why the views on marriage vary in different eras. This paper, based on the view of marriage from the nineteenth- century English novel Pride and Pejudice, is dedicated to elucidating the changes and improvements of view on marriage from feminist perspective via comparing and contrasting the similarities and the differences of people's view on marriage between the early 1800 s and modern times, and then draws a conclusion that the women's degree of receptive education can influence their social status and view on marriage. In modern times the view on marriage based on equality attribute to the sense of happiness of a family and the degree of satisfaction of marriage.展开更多
I Since 1990, as a person in charge of key research projects of the China Tibetology Research Center, I have had opportunities almost every year to conduct field surveys on anthropology in Tibet together with my colle...I Since 1990, as a person in charge of key research projects of the China Tibetology Research Center, I have had opportunities almost every year to conduct field surveys on anthropology in Tibet together with my colleagues. Our investigations focus on the family. The purpose of our surveys is to see social changes in Tibet during the 50 years after the Democratic Reform through the study of the family as a social cell.展开更多
The academic world is still uncertain about the classification of Taisui. It is debating whether Taisui is living or not, myxomycete complex or fungi. The passage studies the 228 finding reports of Taisui in modern Ch...The academic world is still uncertain about the classification of Taisui. It is debating whether Taisui is living or not, myxomycete complex or fungi. The passage studies the 228 finding reports of Taisui in modern China. It confirms that the first finding time of Taisui in modern China is 1963, and the first reported time is 1992. Taisui has been found in 25 administrative divisions. Taisui occurs the most times in Shandong Province. Besides, provinces where Taisui has been found most times are in northern China. Finding locations of Taisui vary from place to place. Taisui is most often found in normal earth layer, with different burying depth. Taisui is mainly found through seeing, tramping, and digging. Taisui findings lack subjective motivations and are connected with the life and production of the finders. Conclusion: Taisui is an object growing in earth layer.展开更多
Queuing models are used to assess the functionality and aesthetics of SCADA systems for supervisory control and data collection.Here,the main emphasis is on how the queuing theory can be used in the system’s design a...Queuing models are used to assess the functionality and aesthetics of SCADA systems for supervisory control and data collection.Here,the main emphasis is on how the queuing theory can be used in the system’s design and analysis.The analysis’s findings indicate that by using queuing models,cost-performance ratios close to the ideal might be attained.This article discusses a novel methodology for evaluating the service-oriented survivability of SCADA systems.In order to evaluate the state of service performance and the system’s overall resilience,the framework applies queuing theory to an analytical model.As a result,the SCADA process is translated using the M^(X)/G/1 queuing model,and the queueing theory is used to evaluate this design’s strategy.The supplemental variable technique solves the queuing problem that comes with the subsequent results.The queue size,server idle time,utilization,and probabilistic generating factors of the distinct operating strategies are estimated.Notable examples were examined via numerical analysis using mathematical software.Because it is used frequently and uses a statistical demarcation method,this tactic is completely acceptable.The graphical representation of this perspective offers a thorough analysis of the alleged limits.展开更多
AIM: To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporatio...AIM: To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporation of serum sodium (MELD-Na), the integrated MELD (iMELD), and the MELD to sodium (MESO) index. METHODS: A total of 166 patients with decompensated cirrhosis were enrolled into the study. MELD, MELD- Na, iMELD and MESO scores were calculated for each patient following the original formula on the first day of admission. All patients were followed up at least 1 year. The predictive prognosis related with the four models was determined by the area under the receiver operating characteristic curve (AUC) of the four parameters. Kaplan-Meier survival curves were made using the cut-offs identif ied by means of receiver operating characteristic (ROC). RESULTS: Out of 166 patients, 38 patients with signifi cantly higher MELD-Na (28.84 ± 2.43 vs 14.72 ± 0.60), iMELD (49.04 ± 1.72 vs 35.52 ± 0.67), MESO scores (1.59 ± 0.82 vs 0.99 ± 0.42) compared to the survivors died within 3 mo (P < 0.001). Of 166 patients, 75 with markedly higher MELD-Na (23.01 ± 1.51 vs 13.78 ± 0.69), iMELD (44.06 ± 1.19 vs 34.12 ± 0.69), MESO scores (1.37 ± 0.70 vs 0.93 ± 0.40) than the survivors died within 1 year (P < 0.001). At 3 mo of enrollment, the iMELD had the highest AUC (0.841), and was followed by the MELD-Na (0.766), MESO (0.723), all larger than MELD (0.773); At 1year, the iMELD still had the highest AUC (0.783), the difference between the iMELD and MELD was statistically significant (P < 0.05). Survival curves showed that the three new models were all clearly discriminated the patients who survived or died in short-term as well as intermediate-term (P < 0.001). CONCLUSION: Three new models, changed with serum sodium (MELD-Na, iMELD, MESO) can exactly predict the prognosis of patients with decompensated cirrhosis for short and intermediate period, and may enhance the prognostic accuracy of MELD. The iMELD is better prognostic model for outcome prediction in patients with decompensated cirrhosis.展开更多
This paper takes the reconstruction of national ethics as the research theme,and investigates the formation and evolution of national ethics in the process of historical development in modern China.Through the study o...This paper takes the reconstruction of national ethics as the research theme,and investigates the formation and evolution of national ethics in the process of historical development in modern China.Through the study of some works,ideological theories and translations,it probes into the origin,subject,path and process of the reconstruction of our national ethics.The study has a certain historical and practical significance in that it gives advice on how we can maintain the subjectivity of our national culture and make it further develop in the world,where different cultures are interacting frequently.展开更多
<span lang="EN-US" style="font-family:;" "="">The domestic cat has been used as a model to carry out comparative research in assisted reproduction, to be applied in wild cats. ...<span lang="EN-US" style="font-family:;" "="">The domestic cat has been used as a model to carry out comparative research in assisted reproduction, to be applied in wild cats. The efficiency in domestic cat IVM concerning </span><span lang="EN-US" style="font-family:;" "="">the </span><span lang="EN-US" style="font-family:;" "="">reproductive status and/or cultivation times has previously been investigated;however, the studies were carried out separately. The objective of this research was to evaluate the maturation of oocytes of domestic cats of different reproductive stages using two different <i>in vitro </i>culture times. The ovaries were obtained by Ooforo-Salpingo-Hysterectomy of cats that were of the following groups: 1) prepubertal, 2) follicular, 3) pregnant or 4) in anestrus. Maturation was carried out with TCM199 medium supplemented with BSA for 24 h and 48 h. On average, 29 ± 25, 20 ± 15, 17 ± 9 and 17 ± 13 oocytes/cat were recovered from the prepubertal follicular, pregnant</span><span lang="EN-US" style="font-family:;" "="">,</span><span lang="EN-US" style="font-family:;" "=""> and anestrus stages, respectively, but did not show a significant difference (<i>P</i></span><span lang="EN-US" style="font-family:;" "=""> ></span><span lang="EN-US"> </span><span lang="EN-US" style="font-family:;" "="">0.05). Also, meiotic maturation did not show a significant difference between the different reproductive stages at 24 h and 48 h, respectively (<i>P</i> > 0.05). However, in the prepubertal and follicular stages, greater oocyte maturation numbers were observed at 48 h compared to 24 h (<i>P</i> < 0.05). In contrast, the aforementioned </span><span lang="EN-US" style="font-family:;" "="">result </span><span lang="EN-US" style="font-family:;" "="">was not observed in the pregnant and anestrus stages (<i>P</i> > 0.05), indicating that the <i>in vitro </i>culture duration is an important factor during <i>in vitro</i> maturation of domestic cat oocytes.</span>展开更多
On November 8, 2022, the symposium on “Deeply Studying and Implementing the Spirit of the 20thCPC National Congress and Adhering to the Chinese Path of Human Rights Development” was held by the China Society for Hum...On November 8, 2022, the symposium on “Deeply Studying and Implementing the Spirit of the 20thCPC National Congress and Adhering to the Chinese Path of Human Rights Development” was held by the China Society for Human Rights Studies in Beijing. Focusing on “the leadership of the CPC and human rights development”, “adapting Marxism to the Chinese context and the needs of our times and human rights theories in contemporary China”, “the Chinese path to modernization and the new form of human rights civilization”, “Chinese human rights solutions and global human rights governance”, “making a better China’s story of advancing human rights and constructing human rights discourse system”, and other topics, the participants reached broad consensus after discussion, and the symposium achieved fruitful results.展开更多
In the early years of Republic of China,Jingyi Garden in The Fragrant Hills of Beijing,the former imperial garden of Qing Dynasty,had turned desolate after the depredation of Anglo-French Allied Force,then the constru...In the early years of Republic of China,Jingyi Garden in The Fragrant Hills of Beijing,the former imperial garden of Qing Dynasty,had turned desolate after the depredation of Anglo-French Allied Force,then the construction of modern garden architecture had started with the operation of The Children’s Philanthropical School of Fragrant Hills.Through reviewing historical literature and field investigation,this paper analyzed the historical background,planning and construction of these modern garden architecture,as well as their types and characteristics,and the utilization of original natural and historical environment of original Jingyi Garden.Based on this,this paper tried to display the historical prospects of modern garden architecture in Jingyi Garden,analyze their characteristics and discover their unique historic value.展开更多
Compared masterpiece of the Latin American Literature--One Hundred Years of Solitude with traditional Chinese significant novel--Ba Ba Ba written by Han Shaogong,the author suggested the notion of time in One Hundred ...Compared masterpiece of the Latin American Literature--One Hundred Years of Solitude with traditional Chinese significant novel--Ba Ba Ba written by Han Shaogong,the author suggested the notion of time in One Hundred Years of Solitude and Ba Ba Ba consists of two levels of narrative:static time and dynamic time. They provide readers with different perspectives in evaluating the thematic issues of the novels.展开更多
Aesthetic Modernity is a western concept.It was based on the development of the historical view.This article focuses on the aesthetic modernity pursuits of modern and contemporary Chinese art and compares it with the ...Aesthetic Modernity is a western concept.It was based on the development of the historical view.This article focuses on the aesthetic modernity pursuits of modern and contemporary Chinese art and compares it with the western culture and modern art under the concept of aesthetics.It also analyses the problems and causes in the process of modernity of Chinese modern and con⁃temporary art,and presents the advice to the further development of Chinese art.展开更多
AIM:To investigate the differentiated whole genome expression profiling of gastric high-and low-grade intraepithelial neoplasia and early-stage adenocarcinoma.METHODS:Gastric specimens from an upper magnifying chromoe...AIM:To investigate the differentiated whole genome expression profiling of gastric high-and low-grade intraepithelial neoplasia and early-stage adenocarcinoma.METHODS:Gastric specimens from an upper magnifying chromoendoscopic targeted biopsy were collected from March 2010 to May 2013.Whole genome expression profiling was performed on 19 low-grade intraepithelial neoplasia(LGIN),20 high-grade intraepithelial neoplasia(HGIN),19 early-stage adenocarcinoma(EGC),and 19 chronic gastritis tissue samples using Agilent 4×44K Whole Human Genome microarrays.Differentially expressed genes between different types of lesions were identified using an unpaired t-test and corrected with the Benjamini and Hochberg false discovery rate algorithm.A gene ontology(GO)enrichment analysis was performed using the Gene Spring software GX 12.6.The differentially expressed gene was verified using a real-time TaqManPCR assay with independent tissue samples,including 26 LGIN,15 HGIN,14 EGC,and 20 chronic gastritis.The expression of G0S2 were further validated by immunohistochemical staining(IHC)in 24 LGIN,40 HGIN,30 EGC and 61 chronic gastritis specimens.RESULTS:The gene expression patterns of LGIN and HGIN tissues were distinct.There were 2521 significantly differentially expressed transcripts in HGIN,with951 upregulated and 1570 downregulated.A GO enrichment analysis demonstrated that the most striking overexpressed transcripts in HGIN compared with LGIN were in the category of metabolism,defense response,and nuclear factorκB(NF-κB)cascade.While the vast majority of transcripts had barely altered expression in HGIN and EGC tissues,only 38 transcripts were upregulated in EGC.A GO enrichment analysis revealed that the alterations of the immune response were most prominent in the progression from HGIN to EGC.It is worth noting that,compared with LGIN,289 transcriptswere expressed at higher levels both in HGIN and EGC.A characteristic gene,G0/G1 switch 2(G0S2)was one of the 289 transcripts and related to metabolism,the immune response,and the NF-κB cascade,and its expression was validated in independent samples through real-time TaqManPCR and immunohistochemical staining.In real-time PCR analysis,the expression of G0S2 was elevated both in HGIN and EGC compared with that in LGIN(P<0.01 and P<0.001,respectively).In IHC analysis,G0S2 immunoreactivity was detected in the cytoplasmic of neoplastic cells,but was undetectable in chronic gastritis cells.The G0S2 expression in HGIN was higher than that of LGIN(P=0.012,χ2=6.28)and EGC(P=0.008,χ2=6.94).CONCLUSION:A clear biological distinction between gastric high-and low-grade intraepithelial neoplasia was identified,and provides molecular evidence for clinical application.展开更多
Entering any Tibetan Buddhist monastery one may feel overwhelmed, struck with awe. But the worshipping seems much more pleasant at the Sepa Monastery which is hidden in deep mountains on the right bank of Tongtian Ri...Entering any Tibetan Buddhist monastery one may feel overwhelmed, struck with awe. But the worshipping seems much more pleasant at the Sepa Monastery which is hidden in deep mountains on the right bank of Tongtian River—the upper reach section of the Yangtze, in Yushu Tibetan Autonomous Prefecture of Qinghai Province. A closer observation can tell that the pleasant feeling comes from the brightness inside the main hall of the monastery, as well as from the lush woods around its buildings, which present a sweet greenness rarely seen展开更多
This paper selects some representative regions to obtain their G-R relation curves according to their seismicity characteristics,by using ML≥2.0 microseismicity data(1970~1993)in North China.The annual occurrence rat...This paper selects some representative regions to obtain their G-R relation curves according to their seismicity characteristics,by using ML≥2.0 microseismicity data(1970~1993)in North China.The annual occurrence rate of events of each magnitude can be inferred from the G-R relation.At the same tune,the actual annual occurrence rate of earthquakes of higher magnitudes can be calculated from historical earthquakes(1300-1993)recorded in the same region.It seems that both results are almost the same.Therefore,the rate of events of higher magnitudes can be obtained by using microseismicity data when the proper region is selected.However,two points should be noticed:(1)The method can only give the annual occurrence rate in a seismicity system and estimate the whole situation of the system.(2)When there is a very large earthquake in and near the period in which the microseismicity data are applied,the actual occurrence rate of the system,including this larger earthquake,cannot be obtained by this method.展开更多
Field experiments were carried out in northern Zhejiang Province. Three insecticides (methamidophos,Shachongshuang and triazophos) were used to control the rice leaffolder Cnaphalocrocis medinalis and rice striped ste...Field experiments were carried out in northern Zhejiang Province. Three insecticides (methamidophos,Shachongshuang and triazophos) were used to control the rice leaffolder Cnaphalocrocis medinalis and rice striped stemborer Chilo suppressalis in rice fields during 18—27 days after transplantating. The impacts of timing and insecticides on the population development of brown planthopper Nilaparavata lugens was surveyed by direct counting on the plants or by tapping method.展开更多
基金the Minas Gerais Research Support Foundation(FAPEMIG,APQ-01392-13 and APQ 01258-17)the Coordination for the Improvement of Higher Education Personnel(Capes,process numbers 88887.613734/2021-00,and 1827878)+1 种基金the FAPEMIG(process number ID 14029)National Council for Scientific and Technological Development(CNPq,process number306845/2021-0)。
文摘Air temperature and photoperiod play an important role in the seedling development for tropical forest species.Both variables are sensitive to climate,and so evaluating thermal and photoperiodic effects on seedling development is fundamental,especially for climate change studies.Methods to quantify thermal time and the energy required for plants to reach a development stage include air temperature and cardinal temperatures.The photoperiod will also affect physiological reactions of a plant and thus its development.Here we evaluated the six thermal time methods widely used to compute thermal requirement,and identified the influence of the photoperiod from the 2015 and2016 growing seasons and 12 sowing dates in Itajubá,Minas Gerais state,Brazil,on seedling development of three native tropical forest species Psidium guajava L.(Myrtaceae),Citharexylum myrianthum Cham.(Verbenaceae),and Bixa orellana L.(Bixaceae).The method used to quantify thermal time influenced the analytical results of seedling development;the one that considered three cardinal temperatures and compared them with the mean air temperature(Method5)performed better in computing thermal requirements.The influence of photoperiod on seedling development was inconclusive for the three species,but all three developed better in mild temperatures(between 13.3℃and 26.9℃)with a photoperiod shorter than 13 h.
基金Sponsored by Hebei Postgraduate Demonstration Curriculum Construction Project(KCJSX2020081)。
文摘Taking the development of the times as the background,the historical evolution of modern architecture is combed from the perspective of the initial stage of industrialization to post-industrialization and then to the information age.It can be seen that there is a close connection between development and modern architecture in the context of the times.With the advancement of science and technology,the construction of buildings has undergone varying degrees of changes due to aesthetics,materials,structure,humanities,and technology.Behind these changes are the results of the progress and development of social productivity.While changing people’s social cognition,it also changes the development process of architecture.
基金This paper is a phased research result of“studies on the outstanding problems with rural development and corresponding countermeasures during the decisive stage in building a moderately prosperous society in all respects”(16JJD810003),a major project of the Key Research Base for Humanities and Social Sciences of the Ministry of Education of the People’s Republic of China.
文摘China’s rural revitalization,which was initiated in the middle and late stages of modernization,features distinct characteristics of the times.It is necessary to approach rural revitalization in China from the aspects of industrial-agricultural coordination,urban-rural integration,and regional balance.Industrial-agricultural coordination concerns forging the“world’s factory”and,more importantly,developing into the“world’s farm”through rural revitalization.Urban-rural integration is not just about urban modernization,but also about rural modernization through rural revitalization.Regional balance requires the promotion of characteristic development in peripheral regions with targeted measures of rural revitalization,as well as the building of highly developed city clusters.
文摘Marriage is a theme influenced by cultural progress. Economic factor is one of the main elements that people of the early nineteenth century considered when deciding a marriage. The pursuit of economic interest results in the advent of some tragic marriages while now it is a side reason. However, women today have made great advancement in education background, employment situation and social status. Women gradually have their economic ability, autonomy and social status. Hence, they began to lay emphasis on the equality and sense of happiness. This is why the views on marriage vary in different eras. This paper, based on the view of marriage from the nineteenth- century English novel Pride and Pejudice, is dedicated to elucidating the changes and improvements of view on marriage from feminist perspective via comparing and contrasting the similarities and the differences of people's view on marriage between the early 1800 s and modern times, and then draws a conclusion that the women's degree of receptive education can influence their social status and view on marriage. In modern times the view on marriage based on equality attribute to the sense of happiness of a family and the degree of satisfaction of marriage.
文摘I Since 1990, as a person in charge of key research projects of the China Tibetology Research Center, I have had opportunities almost every year to conduct field surveys on anthropology in Tibet together with my colleagues. Our investigations focus on the family. The purpose of our surveys is to see social changes in Tibet during the 50 years after the Democratic Reform through the study of the family as a social cell.
文摘The academic world is still uncertain about the classification of Taisui. It is debating whether Taisui is living or not, myxomycete complex or fungi. The passage studies the 228 finding reports of Taisui in modern China. It confirms that the first finding time of Taisui in modern China is 1963, and the first reported time is 1992. Taisui has been found in 25 administrative divisions. Taisui occurs the most times in Shandong Province. Besides, provinces where Taisui has been found most times are in northern China. Finding locations of Taisui vary from place to place. Taisui is most often found in normal earth layer, with different burying depth. Taisui is mainly found through seeing, tramping, and digging. Taisui findings lack subjective motivations and are connected with the life and production of the finders. Conclusion: Taisui is an object growing in earth layer.
文摘Queuing models are used to assess the functionality and aesthetics of SCADA systems for supervisory control and data collection.Here,the main emphasis is on how the queuing theory can be used in the system’s design and analysis.The analysis’s findings indicate that by using queuing models,cost-performance ratios close to the ideal might be attained.This article discusses a novel methodology for evaluating the service-oriented survivability of SCADA systems.In order to evaluate the state of service performance and the system’s overall resilience,the framework applies queuing theory to an analytical model.As a result,the SCADA process is translated using the M^(X)/G/1 queuing model,and the queueing theory is used to evaluate this design’s strategy.The supplemental variable technique solves the queuing problem that comes with the subsequent results.The queue size,server idle time,utilization,and probabilistic generating factors of the distinct operating strategies are estimated.Notable examples were examined via numerical analysis using mathematical software.Because it is used frequently and uses a statistical demarcation method,this tactic is completely acceptable.The graphical representation of this perspective offers a thorough analysis of the alleged limits.
文摘AIM: To investigate the prognostic value of the model for end-stage liver disease (MELD) and three new MELD-based models combination with serum sodium in decompensated cirrhosis patients-the MELD with the incorporation of serum sodium (MELD-Na), the integrated MELD (iMELD), and the MELD to sodium (MESO) index. METHODS: A total of 166 patients with decompensated cirrhosis were enrolled into the study. MELD, MELD- Na, iMELD and MESO scores were calculated for each patient following the original formula on the first day of admission. All patients were followed up at least 1 year. The predictive prognosis related with the four models was determined by the area under the receiver operating characteristic curve (AUC) of the four parameters. Kaplan-Meier survival curves were made using the cut-offs identif ied by means of receiver operating characteristic (ROC). RESULTS: Out of 166 patients, 38 patients with signifi cantly higher MELD-Na (28.84 ± 2.43 vs 14.72 ± 0.60), iMELD (49.04 ± 1.72 vs 35.52 ± 0.67), MESO scores (1.59 ± 0.82 vs 0.99 ± 0.42) compared to the survivors died within 3 mo (P < 0.001). Of 166 patients, 75 with markedly higher MELD-Na (23.01 ± 1.51 vs 13.78 ± 0.69), iMELD (44.06 ± 1.19 vs 34.12 ± 0.69), MESO scores (1.37 ± 0.70 vs 0.93 ± 0.40) than the survivors died within 1 year (P < 0.001). At 3 mo of enrollment, the iMELD had the highest AUC (0.841), and was followed by the MELD-Na (0.766), MESO (0.723), all larger than MELD (0.773); At 1year, the iMELD still had the highest AUC (0.783), the difference between the iMELD and MELD was statistically significant (P < 0.05). Survival curves showed that the three new models were all clearly discriminated the patients who survived or died in short-term as well as intermediate-term (P < 0.001). CONCLUSION: Three new models, changed with serum sodium (MELD-Na, iMELD, MESO) can exactly predict the prognosis of patients with decompensated cirrhosis for short and intermediate period, and may enhance the prognostic accuracy of MELD. The iMELD is better prognostic model for outcome prediction in patients with decompensated cirrhosis.
基金sponsored by the planned project of Philosophy and Social Sciences of Anhui Province in 2014,“Research on the Literature in the Mid-to-late Victorian Age and the Reconstruction of National Morality”(AHSKY2014D110)
文摘This paper takes the reconstruction of national ethics as the research theme,and investigates the formation and evolution of national ethics in the process of historical development in modern China.Through the study of some works,ideological theories and translations,it probes into the origin,subject,path and process of the reconstruction of our national ethics.The study has a certain historical and practical significance in that it gives advice on how we can maintain the subjectivity of our national culture and make it further develop in the world,where different cultures are interacting frequently.
文摘<span lang="EN-US" style="font-family:;" "="">The domestic cat has been used as a model to carry out comparative research in assisted reproduction, to be applied in wild cats. The efficiency in domestic cat IVM concerning </span><span lang="EN-US" style="font-family:;" "="">the </span><span lang="EN-US" style="font-family:;" "="">reproductive status and/or cultivation times has previously been investigated;however, the studies were carried out separately. The objective of this research was to evaluate the maturation of oocytes of domestic cats of different reproductive stages using two different <i>in vitro </i>culture times. The ovaries were obtained by Ooforo-Salpingo-Hysterectomy of cats that were of the following groups: 1) prepubertal, 2) follicular, 3) pregnant or 4) in anestrus. Maturation was carried out with TCM199 medium supplemented with BSA for 24 h and 48 h. On average, 29 ± 25, 20 ± 15, 17 ± 9 and 17 ± 13 oocytes/cat were recovered from the prepubertal follicular, pregnant</span><span lang="EN-US" style="font-family:;" "="">,</span><span lang="EN-US" style="font-family:;" "=""> and anestrus stages, respectively, but did not show a significant difference (<i>P</i></span><span lang="EN-US" style="font-family:;" "=""> ></span><span lang="EN-US"> </span><span lang="EN-US" style="font-family:;" "="">0.05). Also, meiotic maturation did not show a significant difference between the different reproductive stages at 24 h and 48 h, respectively (<i>P</i> > 0.05). However, in the prepubertal and follicular stages, greater oocyte maturation numbers were observed at 48 h compared to 24 h (<i>P</i> < 0.05). In contrast, the aforementioned </span><span lang="EN-US" style="font-family:;" "="">result </span><span lang="EN-US" style="font-family:;" "="">was not observed in the pregnant and anestrus stages (<i>P</i> > 0.05), indicating that the <i>in vitro </i>culture duration is an important factor during <i>in vitro</i> maturation of domestic cat oocytes.</span>
文摘On November 8, 2022, the symposium on “Deeply Studying and Implementing the Spirit of the 20thCPC National Congress and Adhering to the Chinese Path of Human Rights Development” was held by the China Society for Human Rights Studies in Beijing. Focusing on “the leadership of the CPC and human rights development”, “adapting Marxism to the Chinese context and the needs of our times and human rights theories in contemporary China”, “the Chinese path to modernization and the new form of human rights civilization”, “Chinese human rights solutions and global human rights governance”, “making a better China’s story of advancing human rights and constructing human rights discourse system”, and other topics, the participants reached broad consensus after discussion, and the symposium achieved fruitful results.
基金Founded by Humanities and Social Sciences Fund Planning Project of Ministry of Education,PRC (17YJAZH065)。
文摘In the early years of Republic of China,Jingyi Garden in The Fragrant Hills of Beijing,the former imperial garden of Qing Dynasty,had turned desolate after the depredation of Anglo-French Allied Force,then the construction of modern garden architecture had started with the operation of The Children’s Philanthropical School of Fragrant Hills.Through reviewing historical literature and field investigation,this paper analyzed the historical background,planning and construction of these modern garden architecture,as well as their types and characteristics,and the utilization of original natural and historical environment of original Jingyi Garden.Based on this,this paper tried to display the historical prospects of modern garden architecture in Jingyi Garden,analyze their characteristics and discover their unique historic value.
文摘Compared masterpiece of the Latin American Literature--One Hundred Years of Solitude with traditional Chinese significant novel--Ba Ba Ba written by Han Shaogong,the author suggested the notion of time in One Hundred Years of Solitude and Ba Ba Ba consists of two levels of narrative:static time and dynamic time. They provide readers with different perspectives in evaluating the thematic issues of the novels.
文摘Aesthetic Modernity is a western concept.It was based on the development of the historical view.This article focuses on the aesthetic modernity pursuits of modern and contemporary Chinese art and compares it with the western culture and modern art under the concept of aesthetics.It also analyses the problems and causes in the process of modernity of Chinese modern and con⁃temporary art,and presents the advice to the further development of Chinese art.
基金Supported by The specific grants of Public-Funded Projects in the Health Industry,Grant 200902002
文摘AIM:To investigate the differentiated whole genome expression profiling of gastric high-and low-grade intraepithelial neoplasia and early-stage adenocarcinoma.METHODS:Gastric specimens from an upper magnifying chromoendoscopic targeted biopsy were collected from March 2010 to May 2013.Whole genome expression profiling was performed on 19 low-grade intraepithelial neoplasia(LGIN),20 high-grade intraepithelial neoplasia(HGIN),19 early-stage adenocarcinoma(EGC),and 19 chronic gastritis tissue samples using Agilent 4×44K Whole Human Genome microarrays.Differentially expressed genes between different types of lesions were identified using an unpaired t-test and corrected with the Benjamini and Hochberg false discovery rate algorithm.A gene ontology(GO)enrichment analysis was performed using the Gene Spring software GX 12.6.The differentially expressed gene was verified using a real-time TaqManPCR assay with independent tissue samples,including 26 LGIN,15 HGIN,14 EGC,and 20 chronic gastritis.The expression of G0S2 were further validated by immunohistochemical staining(IHC)in 24 LGIN,40 HGIN,30 EGC and 61 chronic gastritis specimens.RESULTS:The gene expression patterns of LGIN and HGIN tissues were distinct.There were 2521 significantly differentially expressed transcripts in HGIN,with951 upregulated and 1570 downregulated.A GO enrichment analysis demonstrated that the most striking overexpressed transcripts in HGIN compared with LGIN were in the category of metabolism,defense response,and nuclear factorκB(NF-κB)cascade.While the vast majority of transcripts had barely altered expression in HGIN and EGC tissues,only 38 transcripts were upregulated in EGC.A GO enrichment analysis revealed that the alterations of the immune response were most prominent in the progression from HGIN to EGC.It is worth noting that,compared with LGIN,289 transcriptswere expressed at higher levels both in HGIN and EGC.A characteristic gene,G0/G1 switch 2(G0S2)was one of the 289 transcripts and related to metabolism,the immune response,and the NF-κB cascade,and its expression was validated in independent samples through real-time TaqManPCR and immunohistochemical staining.In real-time PCR analysis,the expression of G0S2 was elevated both in HGIN and EGC compared with that in LGIN(P<0.01 and P<0.001,respectively).In IHC analysis,G0S2 immunoreactivity was detected in the cytoplasmic of neoplastic cells,but was undetectable in chronic gastritis cells.The G0S2 expression in HGIN was higher than that of LGIN(P=0.012,χ2=6.28)and EGC(P=0.008,χ2=6.94).CONCLUSION:A clear biological distinction between gastric high-and low-grade intraepithelial neoplasia was identified,and provides molecular evidence for clinical application.
文摘Entering any Tibetan Buddhist monastery one may feel overwhelmed, struck with awe. But the worshipping seems much more pleasant at the Sepa Monastery which is hidden in deep mountains on the right bank of Tongtian River—the upper reach section of the Yangtze, in Yushu Tibetan Autonomous Prefecture of Qinghai Province. A closer observation can tell that the pleasant feeling comes from the brightness inside the main hall of the monastery, as well as from the lush woods around its buildings, which present a sweet greenness rarely seen
基金This project was sponsored by the National Natural Science Foundation of China under the contract of No. 49574207
文摘This paper selects some representative regions to obtain their G-R relation curves according to their seismicity characteristics,by using ML≥2.0 microseismicity data(1970~1993)in North China.The annual occurrence rate of events of each magnitude can be inferred from the G-R relation.At the same tune,the actual annual occurrence rate of earthquakes of higher magnitudes can be calculated from historical earthquakes(1300-1993)recorded in the same region.It seems that both results are almost the same.Therefore,the rate of events of higher magnitudes can be obtained by using microseismicity data when the proper region is selected.However,two points should be noticed:(1)The method can only give the annual occurrence rate in a seismicity system and estimate the whole situation of the system.(2)When there is a very large earthquake in and near the period in which the microseismicity data are applied,the actual occurrence rate of the system,including this larger earthquake,cannot be obtained by this method.
文摘Field experiments were carried out in northern Zhejiang Province. Three insecticides (methamidophos,Shachongshuang and triazophos) were used to control the rice leaffolder Cnaphalocrocis medinalis and rice striped stemborer Chilo suppressalis in rice fields during 18—27 days after transplantating. The impacts of timing and insecticides on the population development of brown planthopper Nilaparavata lugens was surveyed by direct counting on the plants or by tapping method.