Cumulative inhalation of respirable coal mine dust(RCMD)can lead to severe lung diseases,including coal worker's pneu-moconiosis(CWP),silicosis,mixed dust pneumoconiosis,dust-related diffuse fibrosis(DDF),and prog...Cumulative inhalation of respirable coal mine dust(RCMD)can lead to severe lung diseases,including coal worker's pneu-moconiosis(CWP),silicosis,mixed dust pneumoconiosis,dust-related diffuse fibrosis(DDF),and progressive massive fibrosis(PMF).Statistics from the number of reported cases showed a significant decrease in the progression of respiratory diseases in the 1990s.However,an unexpected increase in the number of CWP cases was reported in the late 1990s.To date,there has been no comprehensive systematic review to assess all contributing factors to the resurgence of CWP cases.This study aims to investigate the effects of various mining parameters on the prevalence of CWP in coal mines.A systematic review using the preferred reporting items for systematic reviews and meta-analysis(PRISMA)method was conducted to investigate the health effects of RCMD exposure and identify the factors that may contribute to the recent resurgence of CWP cases.The systematic review yielded a total of 401 papers,which were added to the database.The total number of 148 and 208 papers were excluded from the database in the process of screening and eligibility,respectively.Then,18 papers were considered for data selection and full-text assessment.The review revealed that factors including geographic location,mine size,mining operation type,coal-seam thickness,coal rank,changes in mining practices,technology advancement,and engi-neering dust control practices are contributing to the recent resurgence of CWP among coal workers.However,the evidence for root causes is limited owing to the methodological constraints of the studies;therefore,further detailed studies are needed.展开更多
In the present article I will first give a brief summary of the content of the book.Then I discuss some limitations of the book as well as my personal viewpoint about what the book fails to clarify and explain.
Objective The aim of the study was to compare the efficacy and safety of whole brain radiotherapy(WBRT) used alone and combined with stereotactic radiosurgery(SRS) in the treatment of limited(1–4)brain metastases. Me...Objective The aim of the study was to compare the efficacy and safety of whole brain radiotherapy(WBRT) used alone and combined with stereotactic radiosurgery(SRS) in the treatment of limited(1–4)brain metastases. Methods We searched for randomized controlled and matched-pair analysis trials comparing WBRT plus SRS versus WBRT alone for brain metastases. The primary outcomes were the overall survival(OS), intracranial control(IC), and localcontrol(LC). The secondary outcome was radiation toxicity. The log hazard ratios(lnHRs) and their variances were extracted from published Kaplan-Meier curves and pooled using the generic inverse variance method in the RevMan 5.3 software. The non-pooled outcome measures were evaluated using descriptive analysis. Results Three randomized controlled trials and two matched-pair analysis studies were included. There was no difference in the OS for limited brain metastases between the two groups [lnHR 0.91(95% CI 0.76–1.09, P = 0.32) vs. 0.72(95% CI 0.44–1.19, P = 0.20)]. The LC and IC were significantly higher in the combined treatment group [lnHR 0.69(95% CI 0.55–0.86, P = 0.001) vs. 0.41(95% CI 0.29–0.58, P < 0.0001)]. For patients with a single lesion, one trial showed a higher survival in the combined treatment group(median OS: 6.5 months vs. 4.9 months, P = 0.04). The combined treatment was not associated with significantly higher incidence of radiation toxicity. Conclusion Combined treatment with WBRT plus SRS should be recommended for patients with limited brain metastases based on the better LC and IC without increased toxicity. It should also be considered a routine treatment option for patients with solitary brain metastases based on the prolonged OS.展开更多
For determining the accuracy of a calorimeter over the instrument’s entire measuring range,a novel method has been established.For this new approach,(a)benzoic acid(C_(6)H_(5)CO_(2)H) as a certified reference materia...For determining the accuracy of a calorimeter over the instrument’s entire measuring range,a novel method has been established.For this new approach,(a)benzoic acid(C_(6)H_(5)CO_(2)H) as a certified reference material(CRM),(b)SiO_(2) and(c)a mixture of CRM benzoic acid and SiO_(2) have been used.To illustrate the essential difference between 1)the novel analytical method for control of the entire measurement range and 2)the calorimeter calibration,both applications of benzoic acid(BA)have been demonstrated.An experimental result showed that BA was successfully used to check the whole calorimeter measurement range.The results also showed that the same new method was successfully applied to determine the limit of detection and quantification.A new instrument testing process and a new measurement technique have thus been established.In this way,the cost of using CRM to control the accuracy of measuring the entire measuring range of the calorimeter,as shown in this paper,is minimized.The requirements of the ISO/IEC 17025:2017 standard are satisfied.ISO/IEC 17025:2017,together with ISO 9001:2015(quality management systems),ISO 14001:2015(relate to environmental protection)and ISO45001:2018(occupational safety),constitute an integrated quality system by which a testing laboratory may also accredit.展开更多
Close_range photogrammetry is to determine the shape and size of the object,instead of it’s absolute position.Therefore,at first,any translation and rotation of the photogrammetric model of the object caused by whole...Close_range photogrammetry is to determine the shape and size of the object,instead of it’s absolute position.Therefore,at first,any translation and rotation of the photogrammetric model of the object caused by whole geodesic,photographic and photogrammetric procedures in close_range photogrammetry could not be considered.However,it is necessary to analyze all the reasons which cause the deformations of the shape and size and to present their corresponding theories and equations.This situation,of course,is very different from the conventional topophotogrammetry.In this paper some specific characters of limit errors in close_range photogrammerty are presented in detail,including limit errors for calibration of interior elements for close_range cameras,the limit errors of relative and absolute orientations in close_range photogrammetric procedures,and the limit errors of control works in close_range photogrammetry.A theoretical equation of calibration accuracy for close_range camerais given.Relating to the three examples in this paper,their theoretical accuracy requirement of interior elements of camera change in the scope of ±(0.005~0.350) mm.This discussion permits us to reduce accuracy requirement in calibration for an object with small relief,but the camera platform is located in violent vibration environment.Another theoretical equation of relative RMS of base lines ( m S/S ) and the equation RMS of start direction are also presented.It is proved that the m S/S could be equal to the relative RMS of m Δ X / Δ X .It is also proved that the permitting RMS of start direction is much bigger than the traditionally used one.Some useful equations of limit errors in close_range photogrammetry are presented as well.Suggestions mentioned above are perhaps beneficial for increasing efficiency,for reducing production cost.展开更多
As the two fundamental aspects of modern society,the emergency state and the routine state are not exceptions to the rule of law.They just abide by special legal rules and must adhere to the spirit of the rule of law,...As the two fundamental aspects of modern society,the emergency state and the routine state are not exceptions to the rule of law.They just abide by special legal rules and must adhere to the spirit of the rule of law,such as human rights protection and power restrictions and apply the principle of proportionality.In a state of emergency,public interests are faced with major and urgent threats.In this state,the positioning of the purpose,the examination of the consequences,or the measurement of the legal benefits of the purpose and the consequences all have a certain degree of particularity and complexity.In order to increase the rationality of the principle of proportionality in the state of emergency,and to perform its value function scientifically and effectively,it is necessary to adopt loose application standards based on the characteristics of the state of emergency,grasp the key application links,and limit the scope of application to the review of the rationality of the exercise of emergency powers.Judgment of the legitimacy of the purpose of the exercise of emergency powers and the derogation of civil rights such as human dignity are not within the scope of the principle of proportionality.展开更多
This paper addresses the problem of coordinating multiple mobile robots in searching for and capturing a mobile target,with the aim of reducing the capture time.Compared with the previous algorithms,we assume that the...This paper addresses the problem of coordinating multiple mobile robots in searching for and capturing a mobile target,with the aim of reducing the capture time.Compared with the previous algorithms,we assume that the target can be detected by any robot and captured successfully by two or more robots.In this paper,we assume that each robot has a limited communication range.We maintain the robots within a mobile network to guarantee the successful capture.In addition,the motion of the target is modeled and incorporated into directing the motion of the robots to reduce the capture time.A coordination algorithm considering both aspects is proposed.This algorithm can greatly reduce the expected time of capturing the mobile target.Finally,we validate the algorithm by the simulations and experiments.展开更多
The objective of the paper is to compute the optimal burn-out conditions and control requirements that would result in maximum down-range/cross-range performance of a waverider type hypersonic boost-glide(HBG) vehicle...The objective of the paper is to compute the optimal burn-out conditions and control requirements that would result in maximum down-range/cross-range performance of a waverider type hypersonic boost-glide(HBG) vehicle within the medium and intermediate ranges,and compare its performance with the performances of wing-body and lifting-body vehicles vis-a-vis the g-load and the integrated heat load experienced by vehicles for the medium-sized launch vehicle under study.Trajectory optimization studies were carried out by considering the heat rate and dynamic pressure constraints.The trajectory optimization problem is modeled as a nonlinear,multiphase,constraint optimal control problem and is solved using a hp-adaptive pseudospectral method.Detail modeling aspects of mass,aerodynamics and aerothermodynamics for the launch and glide vehicles have been discussed.It was found that the optimal burn-out angles for waverider and wing-body configurations are approximately 5° and 14.8°,respectively,for maximum down-range performance under the constraint heat rate environment.The down-range and cross-range performance of HBG waverider configuration is nearly 1.3 and 2 times that of wing-body configuration respectively.The integrated heat load experienced by the HBG waverider was found to be approximately an order of magnitude higher than that of a lifting-body configuration and 5 times that of a wing-body configuration.The footprints and corresponding heat loads and control requirements for the three types of glide vehicles are discussed for the medium range launch vehicle under consideration.展开更多
Both the long-life and multi-mode versions of LIPS-200 ion thruster are under investigation in LIP(Lanzhou Institute of Physics).To confirm the feasible ranges of the beam current and accel(abbreviation for accelarati...Both the long-life and multi-mode versions of LIPS-200 ion thruster are under investigation in LIP(Lanzhou Institute of Physics).To confirm the feasible ranges of the beam current and accel(abbreviation for accelaration)grid potential to apply to the thruster,the wide-range beam perveance(the state of beam focus)and saddle point potential(the lowest potential along beamlet centerline)characteristics of LIPS-200 are studied with a test-verified PIC-MCC(Particle in Cell-Monte Carlo Collisions)model.These characteristics are investigated with both the initial and the eroded states of the accel grid aperture diameter.The results show that the feasible ranges of these parameters with respect to perveance/crossover(overfocused)limit extend as the operating time accumulates,while the feasible range of accel grid potential narrows due to a reduced EBSF(electron backstreaming failure)margin.The feasible ranges determined by the initial condition are:(i)the beam current up to 0.981 A,and(ii)the accel grid potential up to−85 V.A 23%enlargement of the aperture diameter would bring up to 48 V of EBSF margin loss.展开更多
The systematical and scalable frameworks were provided for estimating the blocking probabilities under asynchronous traffic in optical burst switching(OBS) nodes with limited wavelength conversion capability(LWCC) . T...The systematical and scalable frameworks were provided for estimating the blocking probabilities under asynchronous traffic in optical burst switching(OBS) nodes with limited wavelength conversion capability(LWCC) . The relevant system architectures of limited range and limited number of wavelength converters(WCs) deployed by a share-per-fiber(SPF) mode were developed,and the novel theoretical analysis of node blocking probability was derived by combining the calculation of discouraged arrival rate in a birth-death process and two-dimensional Markov chain model of SPF. The simulation results on single node performance verify the accuracy and effectiveness of the analysis models. Under most scenarios,it is difficult to distinguish the plots generated by the analysis and simulation. As the conversion degree increases,the accuracy of the analysis model worsens slightly. However,the utmost error on burst loss probability is far less than one order of magnitude and hence,still allows for an accurate estimate. Some results are of actual significance to the construction of next-generation commercial OBS backbones.展开更多
This paper presents a detailed study of square reflect array (RA) antenna aperture efficiency (ηa). Effects of quantization-phase and limited phase-range errors on radiation pattern, half-power beam width (HPBW) and ...This paper presents a detailed study of square reflect array (RA) antenna aperture efficiency (ηa). Effects of quantization-phase and limited phase-range errors on radiation pattern, half-power beam width (HPBW) and ηa for different feed locations are investigated. Results show an in-crease in side-lobe levels (SLLs) and a slightly reduction in ηa with quantization-phase augmentation or element phase-range reduction, however, the effects on HPBW are negligible. Nevertheless, the degradation in ηa is negligible when the quantization-phase is lower than 30° or phase-range is more than 300°. Parametric studies have been carried out to provide design guidelines to maximize ηa. It is perceived that the offset-angle plays an important role to determine ηa, especially for feed with narrow beam width.展开更多
基金funded by the National Institute for Occupational Safety and Health (NIOSH) (75D30119C06390).
文摘Cumulative inhalation of respirable coal mine dust(RCMD)can lead to severe lung diseases,including coal worker's pneu-moconiosis(CWP),silicosis,mixed dust pneumoconiosis,dust-related diffuse fibrosis(DDF),and progressive massive fibrosis(PMF).Statistics from the number of reported cases showed a significant decrease in the progression of respiratory diseases in the 1990s.However,an unexpected increase in the number of CWP cases was reported in the late 1990s.To date,there has been no comprehensive systematic review to assess all contributing factors to the resurgence of CWP cases.This study aims to investigate the effects of various mining parameters on the prevalence of CWP in coal mines.A systematic review using the preferred reporting items for systematic reviews and meta-analysis(PRISMA)method was conducted to investigate the health effects of RCMD exposure and identify the factors that may contribute to the recent resurgence of CWP cases.The systematic review yielded a total of 401 papers,which were added to the database.The total number of 148 and 208 papers were excluded from the database in the process of screening and eligibility,respectively.Then,18 papers were considered for data selection and full-text assessment.The review revealed that factors including geographic location,mine size,mining operation type,coal-seam thickness,coal rank,changes in mining practices,technology advancement,and engi-neering dust control practices are contributing to the recent resurgence of CWP among coal workers.However,the evidence for root causes is limited owing to the methodological constraints of the studies;therefore,further detailed studies are needed.
文摘In the present article I will first give a brief summary of the content of the book.Then I discuss some limitations of the book as well as my personal viewpoint about what the book fails to clarify and explain.
文摘Objective The aim of the study was to compare the efficacy and safety of whole brain radiotherapy(WBRT) used alone and combined with stereotactic radiosurgery(SRS) in the treatment of limited(1–4)brain metastases. Methods We searched for randomized controlled and matched-pair analysis trials comparing WBRT plus SRS versus WBRT alone for brain metastases. The primary outcomes were the overall survival(OS), intracranial control(IC), and localcontrol(LC). The secondary outcome was radiation toxicity. The log hazard ratios(lnHRs) and their variances were extracted from published Kaplan-Meier curves and pooled using the generic inverse variance method in the RevMan 5.3 software. The non-pooled outcome measures were evaluated using descriptive analysis. Results Three randomized controlled trials and two matched-pair analysis studies were included. There was no difference in the OS for limited brain metastases between the two groups [lnHR 0.91(95% CI 0.76–1.09, P = 0.32) vs. 0.72(95% CI 0.44–1.19, P = 0.20)]. The LC and IC were significantly higher in the combined treatment group [lnHR 0.69(95% CI 0.55–0.86, P = 0.001) vs. 0.41(95% CI 0.29–0.58, P < 0.0001)]. For patients with a single lesion, one trial showed a higher survival in the combined treatment group(median OS: 6.5 months vs. 4.9 months, P = 0.04). The combined treatment was not associated with significantly higher incidence of radiation toxicity. Conclusion Combined treatment with WBRT plus SRS should be recommended for patients with limited brain metastases based on the better LC and IC without increased toxicity. It should also be considered a routine treatment option for patients with solitary brain metastases based on the prolonged OS.
基金the funding by the Ministry of Education and Science,the Republic of Serbia for Registration(No.451-03-68/2022-14/200052)。
文摘For determining the accuracy of a calorimeter over the instrument’s entire measuring range,a novel method has been established.For this new approach,(a)benzoic acid(C_(6)H_(5)CO_(2)H) as a certified reference material(CRM),(b)SiO_(2) and(c)a mixture of CRM benzoic acid and SiO_(2) have been used.To illustrate the essential difference between 1)the novel analytical method for control of the entire measurement range and 2)the calorimeter calibration,both applications of benzoic acid(BA)have been demonstrated.An experimental result showed that BA was successfully used to check the whole calorimeter measurement range.The results also showed that the same new method was successfully applied to determine the limit of detection and quantification.A new instrument testing process and a new measurement technique have thus been established.In this way,the cost of using CRM to control the accuracy of measuring the entire measuring range of the calorimeter,as shown in this paper,is minimized.The requirements of the ISO/IEC 17025:2017 standard are satisfied.ISO/IEC 17025:2017,together with ISO 9001:2015(quality management systems),ISO 14001:2015(relate to environmental protection)and ISO45001:2018(occupational safety),constitute an integrated quality system by which a testing laboratory may also accredit.
文摘Close_range photogrammetry is to determine the shape and size of the object,instead of it’s absolute position.Therefore,at first,any translation and rotation of the photogrammetric model of the object caused by whole geodesic,photographic and photogrammetric procedures in close_range photogrammetry could not be considered.However,it is necessary to analyze all the reasons which cause the deformations of the shape and size and to present their corresponding theories and equations.This situation,of course,is very different from the conventional topophotogrammetry.In this paper some specific characters of limit errors in close_range photogrammerty are presented in detail,including limit errors for calibration of interior elements for close_range cameras,the limit errors of relative and absolute orientations in close_range photogrammetric procedures,and the limit errors of control works in close_range photogrammetry.A theoretical equation of calibration accuracy for close_range camerais given.Relating to the three examples in this paper,their theoretical accuracy requirement of interior elements of camera change in the scope of ±(0.005~0.350) mm.This discussion permits us to reduce accuracy requirement in calibration for an object with small relief,but the camera platform is located in violent vibration environment.Another theoretical equation of relative RMS of base lines ( m S/S ) and the equation RMS of start direction are also presented.It is proved that the m S/S could be equal to the relative RMS of m Δ X / Δ X .It is also proved that the permitting RMS of start direction is much bigger than the traditionally used one.Some useful equations of limit errors in close_range photogrammetry are presented as well.Suggestions mentioned above are perhaps beneficial for increasing efficiency,for reducing production cost.
文摘As the two fundamental aspects of modern society,the emergency state and the routine state are not exceptions to the rule of law.They just abide by special legal rules and must adhere to the spirit of the rule of law,such as human rights protection and power restrictions and apply the principle of proportionality.In a state of emergency,public interests are faced with major and urgent threats.In this state,the positioning of the purpose,the examination of the consequences,or the measurement of the legal benefits of the purpose and the consequences all have a certain degree of particularity and complexity.In order to increase the rationality of the principle of proportionality in the state of emergency,and to perform its value function scientifically and effectively,it is necessary to adopt loose application standards based on the characteristics of the state of emergency,grasp the key application links,and limit the scope of application to the review of the rationality of the exercise of emergency powers.Judgment of the legitimacy of the purpose of the exercise of emergency powers and the derogation of civil rights such as human dignity are not within the scope of the principle of proportionality.
基金supported by the National Natural Science Foundation of China(No.60434030)
文摘This paper addresses the problem of coordinating multiple mobile robots in searching for and capturing a mobile target,with the aim of reducing the capture time.Compared with the previous algorithms,we assume that the target can be detected by any robot and captured successfully by two or more robots.In this paper,we assume that each robot has a limited communication range.We maintain the robots within a mobile network to guarantee the successful capture.In addition,the motion of the target is modeled and incorporated into directing the motion of the robots to reduce the capture time.A coordination algorithm considering both aspects is proposed.This algorithm can greatly reduce the expected time of capturing the mobile target.Finally,we validate the algorithm by the simulations and experiments.
基金the Chinese Scholarship Council for supporting the research
文摘The objective of the paper is to compute the optimal burn-out conditions and control requirements that would result in maximum down-range/cross-range performance of a waverider type hypersonic boost-glide(HBG) vehicle within the medium and intermediate ranges,and compare its performance with the performances of wing-body and lifting-body vehicles vis-a-vis the g-load and the integrated heat load experienced by vehicles for the medium-sized launch vehicle under study.Trajectory optimization studies were carried out by considering the heat rate and dynamic pressure constraints.The trajectory optimization problem is modeled as a nonlinear,multiphase,constraint optimal control problem and is solved using a hp-adaptive pseudospectral method.Detail modeling aspects of mass,aerodynamics and aerothermodynamics for the launch and glide vehicles have been discussed.It was found that the optimal burn-out angles for waverider and wing-body configurations are approximately 5° and 14.8°,respectively,for maximum down-range performance under the constraint heat rate environment.The down-range and cross-range performance of HBG waverider configuration is nearly 1.3 and 2 times that of wing-body configuration respectively.The integrated heat load experienced by the HBG waverider was found to be approximately an order of magnitude higher than that of a lifting-body configuration and 5 times that of a wing-body configuration.The footprints and corresponding heat loads and control requirements for the three types of glide vehicles are discussed for the medium range launch vehicle under consideration.
基金Group independent research and development projects(No.YF-ZZYF-2021-132).
文摘Both the long-life and multi-mode versions of LIPS-200 ion thruster are under investigation in LIP(Lanzhou Institute of Physics).To confirm the feasible ranges of the beam current and accel(abbreviation for accelaration)grid potential to apply to the thruster,the wide-range beam perveance(the state of beam focus)and saddle point potential(the lowest potential along beamlet centerline)characteristics of LIPS-200 are studied with a test-verified PIC-MCC(Particle in Cell-Monte Carlo Collisions)model.These characteristics are investigated with both the initial and the eroded states of the accel grid aperture diameter.The results show that the feasible ranges of these parameters with respect to perveance/crossover(overfocused)limit extend as the operating time accumulates,while the feasible range of accel grid potential narrows due to a reduced EBSF(electron backstreaming failure)margin.The feasible ranges determined by the initial condition are:(i)the beam current up to 0.981 A,and(ii)the accel grid potential up to−85 V.A 23%enlargement of the aperture diameter would bring up to 48 V of EBSF margin loss.
基金Project(60632010) supported by the National Natural Science Foundation of China
文摘The systematical and scalable frameworks were provided for estimating the blocking probabilities under asynchronous traffic in optical burst switching(OBS) nodes with limited wavelength conversion capability(LWCC) . The relevant system architectures of limited range and limited number of wavelength converters(WCs) deployed by a share-per-fiber(SPF) mode were developed,and the novel theoretical analysis of node blocking probability was derived by combining the calculation of discouraged arrival rate in a birth-death process and two-dimensional Markov chain model of SPF. The simulation results on single node performance verify the accuracy and effectiveness of the analysis models. Under most scenarios,it is difficult to distinguish the plots generated by the analysis and simulation. As the conversion degree increases,the accuracy of the analysis model worsens slightly. However,the utmost error on burst loss probability is far less than one order of magnitude and hence,still allows for an accurate estimate. Some results are of actual significance to the construction of next-generation commercial OBS backbones.
文摘This paper presents a detailed study of square reflect array (RA) antenna aperture efficiency (ηa). Effects of quantization-phase and limited phase-range errors on radiation pattern, half-power beam width (HPBW) and ηa for different feed locations are investigated. Results show an in-crease in side-lobe levels (SLLs) and a slightly reduction in ηa with quantization-phase augmentation or element phase-range reduction, however, the effects on HPBW are negligible. Nevertheless, the degradation in ηa is negligible when the quantization-phase is lower than 30° or phase-range is more than 300°. Parametric studies have been carried out to provide design guidelines to maximize ηa. It is perceived that the offset-angle plays an important role to determine ηa, especially for feed with narrow beam width.