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Introductory Statement by H.E. Ambassador Li Baodong,Head of Chinese Delegation,at the Consideration of the Committee Against Torture on China's 4th and 5th Periodic Reports
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作者 LI BAODONG 《The Journal of Human Rights》 2009年第2期6-8,共3页
Mr. Chairman, Distinguished Members of the Committee, First of all, I would like to extend, on behalf of the Chinese delegation, our greetings and respects to all the distinguished members of the Committee. The Commit... Mr. Chairman, Distinguished Members of the Committee, First of all, I would like to extend, on behalf of the Chinese delegation, our greetings and respects to all the distinguished members of the Committee. The Committee has made enormous efforts and played an important role in promoting the purposes and principles of the Convention and reinforcing the global efforts to ban and prevent torture. The Chinese Government appreciates your endeavor and will continue to support the work of the Committee. 展开更多
关键词 Introductory Statement by H.E Ambassador Li Baodong Head of Chinese Delegation at the Consideration of the Committee Against Torture on China’s 4th and 5th periodic Reports REPORTS LI
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Exploring the Impact of Translanguaging on Chinese-speaking Students’Academic English Writing:Taking CET-4 as an Example
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作者 Ruobing Han 《Journal of Educational Theory and Management》 2023年第2期1-8,共8页
This qualitative research study attempts to discover the real thinking process of learners who are native Chinese speakers in Academic English Writing(AEW)through interviews.Introspecting an EFL learner’s thinking pr... This qualitative research study attempts to discover the real thinking process of learners who are native Chinese speakers in Academic English Writing(AEW)through interviews.Introspecting an EFL learner’s thinking process in English writing is based on two theories:critical period hypothesis and translanguaging.The results of the study indicate that translanguaging has a positive impact on the English CET-4 writing of learners who lack proficiency in English.For those learners who lack proficiency in the second language,translanguaging is an effective auxiliary tool for them to complete AEW. 展开更多
关键词 Academic English writing CET-4 Critical period hypothesis Translanguaging
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A Review of Development of Environmental Protection Information during the 12^(th) Five-Year Plan Period and Its Outlook 被引量:1
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作者 Zhang Fujiang 《Meteorological and Environmental Research》 CAS 2017年第3期67-70,共4页
During the 12^(th)Five-Year Plan period,the environmental protection information work made remarkable achievements,and the construction of nationwide air quality monitoring network was completed; the trinitarian monit... During the 12^(th)Five-Year Plan period,the environmental protection information work made remarkable achievements,and the construction of nationwide air quality monitoring network was completed; the trinitarian monitoring system was established,and environmental emergency command ability enhanced significantly. However,the issues of " information island" and " application silo" are still outstanding,and the application and promotion of new technologies make slow progress; the capacity of information system to support environmental protection business is insufficient,and there is no capacity for decision analysis. In the 13^(th)Five-Year Plan period,it is needed to strengthen the application and promotion of new technologies such as cloud computing,big data,Internet of Things,and spatial information,mainly construct and improve " Cloud Computing Based Environmental Protection( CCBEP) ", " big data platform of ecological environment",and then realize the core objective of improving environmental quality. 展开更多
关键词 the 12th Five-Year PLAN period ENVIRONMENTAL information Review OUTLOOK
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Economists’Judgement on China’s Socio-Economic Development in the 14th Five-Year Plan Period 被引量:2
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作者 Editorial Division of China Economist Chen Sumei 《China Economist》 2020年第4期64-99,共36页
2020 is the final year of China’s 13th Five-Year Plan period and an intersection between the“two centennial goals.”It is also a vital year for drafting the 14th Five-year Plan and embarking on a new journey of soci... 2020 is the final year of China’s 13th Five-Year Plan period and an intersection between the“two centennial goals.”It is also a vital year for drafting the 14th Five-year Plan and embarking on a new journey of socialist modernization.What socio-economic progress has China achieved during the 13th Five-Year Plan period and what are the opportunities,challenges and countermeasures for the 14th Five-Year Plan period?In May 2020,the China Economist conducted a questionnaire survey among economists.Results suggest that during the 13th Five-Year Plan period,China has achieved remarkable progress in the following areas:significant socio-economic development,deepening industry-ICT integration,and rapid growth of new economy;mass entrepreneurship and mass innovation,and enhanced R&D capabilities for cutting-edge technologies;green production and the abatement of air and water pollution;and poverty reduction.In the 14th Five-Year Plan period,opportunities co-exist with challenges for China’s socio-economic development,which brims with resiliency.Surveyed economists felt sanguine about China’s development outlook.Based on the results,surveyed economists believed that the Chinese government should focus on the following priorities during the 14th Five-Year Plan period:expediting industrial transition,strengthening the real economy,and exploring domestic consumption potentials;ramping up research in fundamental science,and accelerating the research of critical technologies;increasing equal access to basic public services;and promoting green development in all respects,including green consumption,production,distribution,innovation,and finance. 展开更多
关键词 14th Five-Year Plan period economic development innovation-led growth public welfare environmental protection
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Small Town Construction in the 13th Five-Year Plan Period: A Case Study of Shangrao City
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作者 Kun YANG Xifeng SHENG 《Asian Agricultural Research》 2016年第10期101-104,共4页
The 12 th Five-Year Plan period was unusual five years in the development of China. Under the dual pressure of complex international environment and arduous domestic reform task,China made outstanding achievements in ... The 12 th Five-Year Plan period was unusual five years in the development of China. Under the dual pressure of complex international environment and arduous domestic reform task,China made outstanding achievements in economic development,which lays a solid foundation for building a moderately prosperous society in all respects in the 13 th Five-Year Plan period. The key and difficult points of building a moderately prosperous society in all respects lie in solving issues concerning agriculture,farmers,and rural areas. The 18 th National Congress of the CPC stated that integrated urban and rural development is the fundamental approach for solving issues concerning agriculture,farmers,and rural areas. As a transitional form from rural areas to urban areas,small town play an important role in integrated urban and rural development. In the 13 th Five-Year Plan period,China should take a new road of characteristic urbanization,energetically develop key towns,central towns,and characteristic towns,use points to drive areas,and promote coordinated progress of urbanization construction and new countryside construction. Focusing on the objective of building a moderately prosperous society in all respects and taking Shangrao City as an example,we analyzed construction of small town,in order to provide scientific theoretical reference for urbanization development,plan preparation,and policy formulation of Shangrao City. 展开更多
关键词 13th Five-Year Plan period Small town construction Shangrao City
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Periodic Orbits of the First Kind in the CR4BP When the Second Primary Is a Triaxial Rigid Body
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作者 M. R. Hassan Payal Singh Md. Aminul Hassan 《International Journal of Astronomy and Astrophysics》 2017年第3期133-153,共21页
The present paper deals with the existence of periodic orbits in the Circular Restricted Four-Body Problem (CR4BP) in two-dimensional co-ordinate system when the second primary is a triaxial rigid body and the third p... The present paper deals with the existence of periodic orbits in the Circular Restricted Four-Body Problem (CR4BP) in two-dimensional co-ordinate system when the second primary is a triaxial rigid body and the third primary of inferior mass (in comparison of the other primaries) is placed at triangular libration point L4 of the Circular Restricted Three-Body Problem (CR3BP). With the help of generating solutions, we formed a basis for the existence of periodic orbits, then an analytical approach given by Hassan et al. [1], was applied to our model of equilateral triangular configuration. It is found that in general solution also;the character of periodic orbits is conserved. For verification of the existence of periodic orbits, we have applied the criterion of Duboshin [2] and found satisfied. 展开更多
关键词 Autonomous Four-Body Problem CR4BP TRIAXIAL Rigid Body REGULARIZATION GENERATING and General Solution periodICITY
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The Implementation of NKTRDP during the 9th Five-Year Plan Period
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《China's Foreign Trade》 2001年第5期17-17,共1页
关键词 the Implementation of NKTRDP during the 9th Five-Year Plan period
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Introductory Remarks by H.E. Duan Jielong,Head of Chinese Delegation,at the Consideration of the Committee on Elimination of All Forms of Racial Discrimination on China's 10th to 13th Periodic Reports
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作者 DUAN JIELONG 《The Journal of Human Rights》 2009年第6期2-5,共4页
Madam Chairwoman, Mr. Rapporteur, Distinguished Members of the Committee, First of all, I would like to extend, on behalf of the Chinese delegation, our heartfelt greetings and respects to all the distinguished membe... Madam Chairwoman, Mr. Rapporteur, Distinguished Members of the Committee, First of all, I would like to extend, on behalf of the Chinese delegation, our heartfelt greetings and respects to all the distinguished members of the Committee. The Committee has made enormous efforts and played an important role in promoting the objectives and principles of the International Convention on Elimination of All Forms of Racial Discrimination. The Chinese Government appreciates your endeavour and will continue to support the work of the Committee. 展开更多
关键词 Introductory Remarks by H.E Duan Jielong Head of Chinese Delegation at the Consideration of the Committee on Elimination of All Forms of Racial Discrimination on China’s 10th to 13th periodic Reports REPORTS
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An Analysis of China's Overall Price Trend During the 12th Five-year Plan Period and Suggestions
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作者 王双正 《China Economist》 2010年第6期120-133,共14页
In this paper,the author first summarizes China’s price operation situation and characteristics since the 1990s,and thenanalyzes inflation shaping factors and types.Based on that,the author raises six inflation early... In this paper,the author first summarizes China’s price operation situation and characteristics since the 1990s,and thenanalyzes inflation shaping factors and types.Based on that,the author raises six inflation early-warning indexes andfully dissects influencing factors of the overall price trend and inflation risks during the 12th Five-year Plan period.Afterthat,the author explains some aspects of price fluctuation that warrants attention during the 12th Five-year Plan period.Finally,the author puts forward policies and suggestions for stabilizing the overall price during the transformation of theeconomic development mode based on our actual situation. 展开更多
关键词 12th Five-year PLAN period overall PRICE level INFLATION TRANSFORMING ECONOMIC development mode
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Variation of sea ice extent in different regions of the Arctic Ocean 被引量:3
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作者 CHEN Ping ZHAO Jinping 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2017年第8期9-19,共11页
Sea ice in the Arctic has been reducing rapidly in the past half century due to global warming. This study analyzes the variations of sea ice extent in the entire Arctic Ocean and its sub regions. The results indicate... Sea ice in the Arctic has been reducing rapidly in the past half century due to global warming. This study analyzes the variations of sea ice extent in the entire Arctic Ocean and its sub regions. The results indicate that sea ice extent reduction during 1979-2013 is most significant in summer, following by that in autumn, winter and spring. In years with rich sea ice, sea ice extent anomaly with seasonal cycle removed changes with a period of 4-6 years. The year of 2003-2006 is the ice-rich period with diverse regional difference in this century. In years with poor sea ice, sea ice margin retreats further north in the Arctic. Sea ice in the Fram Strait changes in an opposite way to that in the entire Arctic. Sea ice coverage index in melting-freezing period is an critical indicator for sea ice changes, which shows an coincident change in the Arctic and sub regions. Since 2002, Region C2 in north of the Pacific sector contributes most to sea ice changes in the central Aarctic, followed by C1 and C3. Sea ice changes in different regions show three relationships. The correlation coefficient between sea ice coverage index of the Chukchi Sea and that of the East Siberian Sea is high, suggesting good consistency of ice variation. In the Atlantic sector, sea ice changes are coincided with each other between the Kara Sea and the Barents Sea as a result of warm inflow into the Kara Sea from the Barents Sea. Sea ice changes in the central Arctic are affected by surrounding seas. 展开更多
关键词 Key words: Arctic sea ice extent period of 4-6 years sea ice margin sea ice coverage indices
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Frontier and Evolution of Marketing Discipline Based on Scientific Metrological Analysis of Top 4 Marketing Periodicals in 2009-2013
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作者 Shenpeng ZHANG 《Asian Agricultural Research》 2015年第12期16-22,共7页
Using scientific metrological method,this paper analyzed all literature published by top 4 marketing periodicals( JCR,JM,JMR,and MS) in 2009- 2013. It is intended to find out hot issues and frontier topics of current ... Using scientific metrological method,this paper analyzed all literature published by top 4 marketing periodicals( JCR,JM,JMR,and MS) in 2009- 2013. It is intended to find out hot issues and frontier topics of current marketing research through cluster analysis of key words,get to know cooperation and exchange of organizations through analysis of organization cooperative network,explore new topics of marketing researches with the aid of analysis of abrupt change words,and explore evolution path and development rules of marketing researches through co-citation network analysis. 展开更多
关键词 TOP 4 MARKETING periodicals Citespace LITERATURE metrology Mapping knowledge domain
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"A Perfect Heroine in Foreign Travel." Female Mobile Identities and Southern Italy in the 19th Century Non-feminist Periodical Press
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作者 Marcella Romeo 《Journal of Literature and Art Studies》 2016年第11期1263-1277,共15页
This essay focuses on the interaction between the publication of female travel writing about the South of Italy in non-feminist 19th century British periodicals, and the circulation of a transgressive model of feminin... This essay focuses on the interaction between the publication of female travel writing about the South of Italy in non-feminist 19th century British periodicals, and the circulation of a transgressive model of femininity centred on the concepts of mobility, vitality and visibility. The choice of Southern Italy, an anti-tourist destination that since the era of the Grand Tour had been considered dangerous for men, let alone for women, magnifies female heroic attitudes and contaminates female conventional domestic purity enhancing the concept of an unfixed female identity. The publication of a travelogue, a mostly non-fictional genre, on an innovative and reactive medium, was a manifest act of transgression with respect to fixed social order, which gave visibility and credibility to a different model of femininity, an anti-Angel icon. A new form of narration displays adventurous women able to cross the private sphere and to write/publish authentic accounts of their transitional experience in a public, male-dominated sphere. 展开更多
关键词 women travelogues 19th century non-feminist periodicals Southern Italy VISIBILITY mobility anti-Angel icon
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The Sociocultural Analysis of the Development of Communism Movement in China
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作者 CUI Meng ZHANG Guopeng 《Cultural and Religious Studies》 2021年第8期365-375,共11页
The initiation of the communism group and the founding of the Communist Party of China are deeply rooted in China’s political,economic,and social environments,which are not simply the result of Soviet Russia’forced ... The initiation of the communism group and the founding of the Communist Party of China are deeply rooted in China’s political,economic,and social environments,which are not simply the result of Soviet Russia’forced export of revolution.Out of the complete disappointment in China’s political reality and the profound reflection on its economic oppression,Chinese progressive intellectuals have yearned for one ideal society since the Republic of China,which is represented by socialism.The practical successful road provided by October Revolution caters to China’s trend.Therefore,the early Chinese communists begin to change their clothes and enter the labor masses.They look forward to establishing a revolutionary proletarian regime and carrying on economic career based on communist principle so as to promote national construction.Under the long-term promotion of the early communists,the former poor and undisciplined working class would bring the concept of socialism into their own life. 展开更多
关键词 may 4th period Communism Movement working class
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Periodic Solutions for the Higher Order Differential Equations with Multiple Delays
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作者 梁心 从福仲 《Northeastern Mathematical Journal》 CSCD 2008年第6期558-564,共7页
By Fourier analysis techniques and Schauder fixed point theorem, we study the existence of periodic solutions for a class of even order differential equations with multiple delays. The result obtained is a generalizat... By Fourier analysis techniques and Schauder fixed point theorem, we study the existence of periodic solutions for a class of even order differential equations with multiple delays. The result obtained is a generalization of the results developed by W. Layton to the case of multiple delays. 展开更多
关键词 (2k)th-order differential equation multiple delay periodic solution Schauder fixed point theorem
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Goals for textile machinery industry during the 11th Five-Year Plan period
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《China Textile》 2006年第3期90-90,共1页
关键词 THAN Goals for textile machinery industry during the 11th Five-Year Plan period
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FRACTIONAL INTEGRALS OF PERIODIC FUNCTIONS OF SEVERAL VARIABLES
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作者 Wang Shiming 《Analysis in Theory and Applications》 1993年第1期82-96,共15页
In this paper it has been systematically studied the imbedding properties o f fractional integral operators of periodic functions of several variables,and isomorphic properties of fractional intregral operators in the... In this paper it has been systematically studied the imbedding properties o f fractional integral operators of periodic functions of several variables,and isomorphic properties of fractional intregral operators in the spaces of Lipschitz continuous functions. It has also been proved that the space of fractional integration,the space of Lipschitz continuous functions and the Sobolev space are identical in L^2-norm.Results obtainedhere are not true for fractional integrals(or Riesz potentials)in R^n. 展开更多
关键词 TH FRACTIONAL INTEGRALS of periodIC FUNCTIONS of SEVERAL VARIABLES
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COPD急性加重期患者外周血单个核细胞SOCS-1、TLR4 mRNA及血清cTnT、尿酸水平变化分析
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作者 云俊杰 徐影 《北华大学学报(自然科学版)》 CAS 2024年第2期185-190,共6页
目的探讨慢性阻塞性肺疾病(COPD)急性加重期患者外周血单个核细胞中细胞因子信号抑制蛋白-1(SOCS-1)、Toll样受体4(TLR4)mRNA水平及血清心肌肌钙蛋白T(cTnT)、尿酸水平变化。方法收集COPD急性加重期(组)患者70例,COPD稳定期(组)患者40例... 目的探讨慢性阻塞性肺疾病(COPD)急性加重期患者外周血单个核细胞中细胞因子信号抑制蛋白-1(SOCS-1)、Toll样受体4(TLR4)mRNA水平及血清心肌肌钙蛋白T(cTnT)、尿酸水平变化。方法收集COPD急性加重期(组)患者70例,COPD稳定期(组)患者40例,对照组健康志愿者40名。检测外周血单个核细胞SOCS-1、TLR4 mRNA水平及血清cTnT、尿酸浓度;行肺功能检查并记录相关指标(FEV1、FEV1%、FEV1/FVC%)。对COPD急性加重期患者进行1 a随访,分为预后不良组和预后良好组。对外周血单个核细胞SOCS-1、TLR4 mRNA水平、血清cTnT、尿酸浓度行Pearson相关性分析,并对COPD急性加重期患者预后评估价值进行ROC曲线分析。结果COPD急性加重期组SOCS-1 mRNA表达水平明显低于COPD稳定期组、对照组,TLR4 mRNA水平及血清cTnT、尿酸浓度明显高于COPD稳定期组和对照组(均P<0.01)。COPD急性加重期组FEV1、FEV1%、FEV1/FVC%明显低于COPD稳定期组和对照组(P<0.05)。COPD急性加重期患者FEV1/FVC%与外周血单个核细胞SOCS-1 mRNA表达水平呈正相关关系(P<0.01),与外周血单个核细胞TLR4 mRNA水平及血清cTnT、尿酸浓度呈负相关关系(P<0.01)。预后不良组SOCS-1 mRNA水平明显低于预后良好组,TLR4 mRNA水平及血清cTnT、尿酸浓度明显高于预后良好组(P<0.05)。外周血单个核细胞SOCS-1、TLR4 mRNA水平及血清cTnT、尿酸联合检测对COPD急性加重期患者预后具有较高的评估价值。结论COPD急性加重期患者SOCS-1低表达,TLR4、cTnT、尿酸高表达,且与肺功能水平密切相关,联合检测对患者预后具有较高的评估价值。 展开更多
关键词 慢性阻塞性肺疾病 急性加重期 细胞因子信号抑制蛋白-1 Toll样受体4 心肌肌钙蛋白T 尿酸 预后
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大兴安岭多年冻土区两种水体温室气体浓度动态与冬季储存特征 被引量:1
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作者 薛璟 陈辛安 +1 位作者 王宪伟 孙晓新 《生态学报》 CAS CSCD 北大核心 2024年第5期1918-1927,共10页
北方内陆水体是温室气体排放的热点,对量化区域碳收支起重要作用,但其排放的季节变化尚不清楚。观测了大兴安岭多年冻土区府库奇河及其改道形成的牛轭湖(演替晚期)冻结期冰层中储存的二氧化碳(CO_(2))和甲烷(CH_(4))浓度,并比较了两种... 北方内陆水体是温室气体排放的热点,对量化区域碳收支起重要作用,但其排放的季节变化尚不清楚。观测了大兴安岭多年冻土区府库奇河及其改道形成的牛轭湖(演替晚期)冻结期冰层中储存的二氧化碳(CO_(2))和甲烷(CH_(4))浓度,并比较了两种水体中CO_(2)和CH_(4)浓度在三个不同时期(冻结期、非冻结期、春季融化)的差异。结果表明:两种水体CO_(2)和CH_(4)浓度季节变化存在差异。牛轭湖在冻结期水体中CO_(2)和CH_(4)浓度最高,有明显的冰下积累现象,其中CH_(4)浓度平均值为(2.21±0.54)μmo/L,分别是非冻结期和春季融化期水体CH_(4)浓度的5倍和14倍。河流水体中CO_(2)和CH_(4)浓度最高出现在春季融化期,显著高于非冻结期和冻结期(P<0.05)。水中CO_(2)和CH_(4)浓度受多种环境因子的影响,与可溶性有机碳(DOC)正相关(P<0.05),与溶解氧(DO)、水温为负相关(P<0.05)。冻结期冰层形成后,温室气体会以冰气泡的形式存储在冰层中,气泡的主要成分是CO_(2)和CH_(4),其中CO_(2)占90%以上。由于冰气泡中CO_(2)和CH_(4)浓度约为冰下水体浓度的1%—30%,忽略冰层中储存的温室气体将会增加北方水体碳排放的不确定性。研究明确了大兴安岭多年冻土区两种水体溶解性CO_(2)和CH_(4)的季节变化特征与冬季温室气体储存能力,为深入认知该区域水体碳循环过程提供重要数据支持。 展开更多
关键词 溶解CO_(2)和CH_(4)浓度 冰层覆盖时期 内陆水域 冰气泡
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三江平原农田排水期流域水体CH_(4)排放特征及影响因素
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作者 刘凯明 张海 +5 位作者 李霞 王明国 杨涛 李军 白莉 刘小龙 《中国环境科学》 EI CAS CSCD 北大核心 2024年第6期3078-3090,共13页
在施肥和土壤淋溶等多种因素的影响下,农业流域水体甲烷(CH_(4))的源汇关系尚不明确,目前对于农业流域水体CH_(4)排放的监测和研究仍然不足.本研究选取三江平原的浓江流域为研究对象,利用顶空平衡法和扩散模型法对该流域不同水体的CH_(4... 在施肥和土壤淋溶等多种因素的影响下,农业流域水体甲烷(CH_(4))的源汇关系尚不明确,目前对于农业流域水体CH_(4)排放的监测和研究仍然不足.本研究选取三江平原的浓江流域为研究对象,利用顶空平衡法和扩散模型法对该流域不同水体的CH_(4)浓度和排放通量进行监测和估算.结果表明:浓江流域水体普遍为CH_(4)的排放源,鸭绿河、浓江河流、沟渠和稻田水体的CH_(4)排放通量范围分别为0.51~99.60、0.97~20.44、4.13~20.90和24.84~58.07mg/(m^(2)·d),且沟渠和稻田水体的CH_(4)排放通量较高,分别为浓江河流的2倍和7倍.在鸭绿河干流和沟渠水体中,CH_(4)浓度与pH值和溶解氧(DO)均呈显著负相关,浓江干流的CH_(4)浓度与DO呈显著正相关.浓江干流和沟渠水体的CH_(4)浓度与溶解性有机碳(DOC)呈显著正相关,表明排水期农业有机肥的使用会促进水体CH_(4)的产生.流经湿地浅水区和受农田施肥影响的河段水体具有较高的CH_(4)浓度和排放通量,表明CH_(4)排放受到了土地利用方式的显著影响.相比于全球其他农业河流,排水期浓江流域河水在排水期具有较高的CH_(4)浓度和较低的CH_(4)排放通量,较低风速缓解了水-气界面的排放.而沟渠水体排水期间较低的CH_(4)排放通量主要受富氧状态的影响.三江平原作为典型的东北黑土农业区,探究其农业流域CH_(4)的产生和排放对于未来区域的碳收支平衡和碳排放评估具有重要意义. 展开更多
关键词 农业流域 排水期 温室气体CH_(4) 产生与排放
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溃疡性结肠炎患者血清趋化因子配体19、干扰素调节因子4水平及临床意义
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作者 孔令甲 赵维波 周宪伟 《检验医学与临床》 CAS 2024年第10期1360-1364,共5页
目的探讨溃疡性结肠炎(UC)患者血清趋化因子配体19(CCL19)、干扰素调节因子4(IRF4)水平及临床意义。方法选择2020年6月至2022年5月在该院住院治疗的105例UC患者为UC组,另选取83例健康体检者为对照组。根据Mayo评分将UC患者分为缓解期组(... 目的探讨溃疡性结肠炎(UC)患者血清趋化因子配体19(CCL19)、干扰素调节因子4(IRF4)水平及临床意义。方法选择2020年6月至2022年5月在该院住院治疗的105例UC患者为UC组,另选取83例健康体检者为对照组。根据Mayo评分将UC患者分为缓解期组(n=35)和活动期组(n=70)。根据活动期病情严重程度,将活动期UC患者分为轻度组(n=19)、中度组(n=23)和重度组(n=28)。根据患者预后情况分为预后良好组和预后不良组。采用酶联免疫吸附试验检测血清CCL19、IRF4水平;采用Pearson相关分析血清CCL19、IRF4水平与Mayo评分的相关性;采用多因素Logistic回归分析影响UC患者预后的因素;采用受试者工作特征(ROC)曲线分析血清CCL19、IRF4水平对UC患者预后不良的预测价值。结果UC组血清CCL19、IRF4水平明显高于对照组,差异均有统计学意义(P<0.05)。缓解期组血清CCL19、IRF4水平低于活动期组,差异均有统计学意义(P<0.05)。重度组血清CCL19、IRF4水平明显高于轻度组和中度组,且中度组明显高于轻度组,差异均有统计学意义(P<0.05)。预后良好组CCL19、IRF4、C反应蛋白(CRP)、红细胞沉降率(ESR)水平明显低于预后不良组,差异有统计学意义(P<0.05)。相关分析结果显示,UC患者血清CCL19、IRF4水平均与Mayo评分呈正相关(r=0.426、0.471,P<0.05)。血清CCL19、IRF4水平升高是UC患者预后不良的危险因素(P<0.05)。ROC曲线分析结果显示,血清CCL19、IRF4水平单独及联合预测UC患者预后不良的曲线下面积(AUC)分别为0.798、0.752、0.845。结论UC患者血清CCL19、IRF4水平均升高,且与患者病情和临床预后关系密切,可作为UC临床预后评估的潜在指标。 展开更多
关键词 溃疡性结肠炎 趋化因子配体19 干扰素调节因子4 病情严重程度 活动期
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