Ordovician reservoirs in Fuxian area:Gas accumulation patterns and their implications for the exploration of lower Paleozoic carbonates in the southern Ordos Basin

In recent years,the Fuxian area in the southeastern Ordos Basin has undergone significant exploration,with industrial gas flow tested in wells drilled into the Ordovician marine carbonates.Despite this,the gas accumulation patterns of this area are not fully understood,posing challenges for further exploration.Our analysis of geological conditions indicates that the Ordovician Majiagou Formation in this area hosts two gas plays:one found in weathering crusts and the other found in interior of the formation.We investigated various typical gas reservoirs in the area,focusing on differentiating the geological conditions and factors controlling gas accumulation in the weathering-crust and interior gas reservoirs.The results suggest three primary gas accumulation patterns in the Majiagou Formation in the Fuxian area:(1)upper gas accumulation in weathering crusts,present in the high parts of landforms such as residual paleo-hills or buried paleo-platform(Pattern I);(2)the stereoscopic pattern with gas accumulation in both weathering crusts and strata interior,arising in high parts of landforms such as residual paleo-hills or buried paleo-platforms(Pattern II);(3)lower gas accumulation in strata interior,occurring in the upper reaches and on both sides of paleo-trenches(Pattern III).This study will serve as a geological basis for future exploration deployment in the Fuxian area.

The Contribution of United States Aircraft Reconnaissance Data to the China Meteorological Administration Tropical Cyclone Intensity Data:An Evaluation of Homogeneity

This paper investigates the homogeneity of United States aircraft reconnaissance data and the impact of these data on the homogeneity of the tropical cyclone(TC)best track data for the seasons 1949-1987 generated by the China Meteorological Administration(CMA).The evaluation of the reconnaissance data shows that the minimum central sea level pressure(MCP)data are relatively homogeneous,whereas the maximum sustained wind(MSW)data show both overestimations and spurious abrupt changes.Statistical comparisons suggest that both the reconnaissance MCP and MSW were well incorporated into the CMA TC best track dataset.Although no spurious abrupt changes were evident in the reconnaissance-related best track MCP data,two spurious changepoints were identified in the remainder of the best-track MCP data.Furthermore,the influence of the reconnaissance MSWs seems to extend to the best track MSWs unrelated to reconnaissance,which might reflect the optimistic confidence in making higher estimates due to the overestimated extreme wind“observations”.In addition,the overestimation of either the reconnaissance MSWs or the best track MSWs was greater during the early decades compared to later decades,which reflects the important influence of reconnaissance data on the CMA TC best track dataset.The wind-pressure relationship(WPR)used in the CMA TC best track dataset is also evaluated and is found to overestimate the MSW,which may lead to inhomogeneity within the dataset between the aircraft reconnaissance era and the satellite era.

Increased number of symptoms during the acute phase of SARS-CoV-2 infection in athletes is associated with prolonged time to return to full sports performance—AWAREⅧ

Purpose The aim of the study was to identify factors associated with prolonged time to return to full performance(RTFP)in athletes with recent severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection.Methods Prospective cohort study with cross sectional analysis.A total of 84 athletes with confirmed SARS-CoV-2 infection assessed at a coronavirus disease 2019 recovery clinic gave a history of age,sex,type/level of sport,co-morbidities,pre-infection training hours,and 26 acute SARS-CoV-2 symptoms from 3 categories(“nose and throat”,“chest and neck”,and“whole body”/systemic).Data on days to RTFP were obtained by structured interviews.Factors associated with RTFP were demographics,sport participation,history of co-morbidities,pre-infection training history,and acute symptoms(type,number).Outcomes were:(a)days to RTFP(median,interquartile range(IQR))in asymptomatic(n=7)and symptomatic athletes(n=77),and(b)hazard ratios(HRs;95%confidence interval)for symptomatic athletes with vs.without a factor(univariate,multiple models).HR<1 was predictive of higher percentage chance of prolonged RTFP.Significance was p<0.05.Results Days to RTFP were 30 days(IQR:23–40)for asymptomatic and 64 days(IQR:42–91)for symptomatic participants(p>0.05).Factors associated with prolonged RTFP(univariate models)were:females(HR=0.57;p=0.014),endurance athletes(HR=0.41;p<0.0001),co-morbidity number(HR=0.75;p=0.001),and respiratory disease history(HR=0.54;p=0.026).In symptomatic athletes,prolonged RTFP(multiple models)was significantly associated with increased“chest and neck”(HR=0.85;p=0.017)and“nose and throat”(HR=0.84;p=0.013)symptoms,but the association was more profound between prolonged RFTP and increased total number of“all symptoms”(HR=0.91;p=0.001)and“whole body”/systemic(HR=0.82;p=0.007)symptoms.Conclusion A larger number of total symptoms and specifically“whole body”/systemic symptoms during the acute phase of SARS-CoV-2 infection in athletes is associated with prolonged RTFP.

Symptom presentation and evolution in the first 48 hours after injury are associated with return to play after concussion in elite Rugby Union

Background:Return to play(RTP)in elite rugby is managed using a 6-stage graduated RTP protocol,which can result in clearance to play within 1 week of injury.We aimed to explore how symptom,cognitive,and balance presentation and evolution during concussion screens 2 h(head injury assessment(HIA2)and 48 h(HIA3)after injury were associated with time to RTP)to identify whether a more conservative graduated RTP may be appropriate.Methods:A retrospective cohort study was conducted in 380 concussed rugby players from elite men’s rugby over 3 consecutive seasons.Players were classified as shorter or longer returns,depending on whether RTP occurred within 7 days(allowing them to be considered to play the match 1 week after injury)or longer than 8 days,respectively.Symptom,cognitive,and balance performance during screens was assessed relative to baseline(normal or abnormal)and to the preceding screen(improving or worsening).Associations between sub-test abnormalities and RTP time were explored using odds ratios(OR,longer vs.shorter).Median day absence was compared between players with abnormal or worsening results and those whose results were normal or improving.Results:Abnormal symptom results during screens 2 h and 48 h after concussion were associated with longer return time(HIA2:OR=2.21,95%confidence interval(95%CI):1.39-3.50;HIA3:OR=3.30,95%CI:1.89-5.75).Worsening symptom number or severity from the time of injury to 2 h and 48 h post-injury was associated with longer return(HIA2:OR=2.49,95%CI:1.36-4.58;HIA3:OR=3.34,95%CI:1.10-10.15).Median days absence was greater in players with abnormal symptom results at both HIA2 and HIA3.Cognitive and balance performance were not associated with longer return and did not affect median days absence.Conclusion:Symptom presentation and evolution within 48 h of concussion were associated with longer RTP times.This may guide a more conservative approach to RTP,while still adhering to individualized concussion management principles.

Enhancing Proficiency in Quadratic Equations and Functions Through the MILAPlus Strategy

This study investigates the efficacy of the Mathematics Independent Learning Activity Practice and Play Unite Scheme(MILAPlus)as an instructional strategy to improve the proficiency levels of Grade 9 students in quadratic equations and functions through a study carried out at Quezon National High School.The research involved 116 Grade 9 students and utilized a quantitative approach,incorporating both pre-assessment and post-assessment measures.The research utilizes a quasi-experimental design,examining the academic performance of students before and after the introduction of MILAPlus.The pre-assessment establishes a baseline,and the subsequent post-assessment measures the impact of the instructional strategy.Statistical analyses,including t-tests,assess the significance of differences in mean scores and mean percentage scores,providing quantitative insights into the effectiveness of MILAPlus.Findings from the study revealed a statistically significant improvement in both mean scores and mean percentage scores after the utilization of MILAPlus,indicating enhanced proficiency in quadratic equations and functions.The Mean Proficiency Scores(MPS)also showed a substantial increase,demonstrating a marked improvement in overall proficiency levels among Grade 9 students.In light of the results,recommendations were given including the continued utilization of MILAPlus as an instructional strategy and aligning its development with prescribed learning competencies.Emphasizing the consistent adherence to policies and guidelines for MILAPlus implementation is suggested for sustaining positive effects on students’long-term performance in mathematics.This research contributes valuable insights into the practical application and effectiveness of MILAPlus within the context of Grade 9 mathematics education at Quezon National High School.

Procedural Transition in the Principle of the Best Interests of the Child in the Eyes of the European Court of Human Rights

The principle of the best interests of the child,as a criterion for substantive review,is conceptually ambiguous and uncertain in its application.To mitigate this dilemma in the application of the principle of the best interests of the child,the European Court of Human Rights(ECHR)has made a procedural transition in the interpretation and application of this principle,shifting from conducting specific proportionality analysis or interests balancing in cases related to children to examining whether States Parties have applied the principle of the best interests of the child in their judicial procedures.Moreover,ECHR has developed three procedural review schemes:holistic reviews,key factors-based reviews and factor list-based reviews.Compared with substantive reviews,procedural reviews adhere to the ECHR doctrine of margin of appreciation,restrict the free discretion of the court,give play to the effect of procedural autonomy,and pursue the value of subjective procedural justice,which has its own unique theoretical value and practical significance,and provides a feasible reference for China to interpret and apply the principle of the best interests of the child.

Political Parties Have a Role to Play in Innovating upon in Global Economic Governance:Sidelights of "The CPC in Dialogue with the World 2016"

BETWEEN OCTOBER 13 AND 15,2016,hosted by the International Department,the CPC Central Committee and organized by the CPC Chongqing Municipal Committee,the CPC in Dialogue with the World 2016was held in Chongqing.Themed'Innovation in Global Economic Governance:Initiatives and Actions of Political Parties',the annual event was

Play therapy in children with autism:Its role,implications,and limitations

Play is a pleasurable physical or mental activity that enhances the child’s skills involving negotiation abilities,problem-solving,manual dexterity,sharing,decision-making,and working in a group.Play affects all the brain's areas,structures,and functions.Children with autism have adaptive behavior,adaptive response,and social interaction limitations.This review explores the different applications of play therapy in helping children with autism disorder.Play is usually significantly impaired in children with autism.Play therapy is mainly intended to help children to honor their unique mental abilities and developmental levels.The main aim of play therapy is to prevent or solve psychosocial difficulties and achieve optimal child-healthy growth and development.Play therapy helps children with autism to engage in play activities of their interest and choice to express themselves in the most comfortable ways.It changes their way of self-expression from unwanted behaviors to more non-injurious expressive behavior using toys or activities of their choice as their words.Play therapy also helps those children to experience feeling out various interaction styles.Every child with autism is unique and responds differently.Therefore,different types of intervention,like play therapy,could fit the differences in children with autism.Proper evaluation of the child is mandatory to evaluate which type fits the child more than the others.This narrative review revised the different types of play therapy that could fit children with autism in an evidence-based way.Despite weak evidence,play therapy still has potential benefits for patients and their families.

Detection of Novel BEST1 Variations in Autosomal Recessive Bestrophinopathy Using Third-generation Sequencing

Objective:Autosomal recessive bestrophinopathy(ARB),a retinal degenerative disease,is characterized by central visual loss,yellowish multifocal diffuse subretinal deposits,and a dramatic decrease in the light peak on electrooculogram.The potential pathogenic mechanism involves mutations in the BEST1 gene,which encodes Ca2+-activated Cl−channels in the retinal pigment epithelium(RPE),resulting in degeneration of RPE and photoreceptor.In this study,the complete clinical characteristics of two Chinese ARB families were summarized.Methods:Pacific Biosciences(PacBio)single-molecule real-time(SMRT)sequencing was performed on the probands to screen for disease-causing gene mutations,and Sanger sequencing was applied to validate variants in the patients and their family members.Results:Two novel mutations,c.202T>C(chr11:61722628,p.Y68H)and c.867+97G>A,in the BEST1 gene were identified in the two Chinese ARB families.The novel missense mutation BEST1 c.202T>C(p.Y68H)resulted in the substitution of tyrosine with histidine in the N-terminal region of transmembrane domain 2 of bestrophin-1.Another novel variant,BEST1 c.867+97G>A(chr11:61725867),located in intron 7,might be considered a regulatory variant that changes allele-specific binding affinity based on motifs of important transcriptional regulators.Conclusion:Our findings represent the first use of third-generation sequencing(TGS)to identify novel BEST1 mutations in patients with ARB,indicating that TGS can be a more accurate and efficient tool for identifying mutations in specific genes.The novel variants identified further broaden the mutation spectrum of BEST1 in the Chinese population.

Morphological and functional changes in the macular area in diabetic macular edema after a single intravitreal injection of aflibercept

AIM:To evaluate the changes in macular morphology and function after a single intravitreal injection of aflibercept in diabetic macular edema(DME)using optical coherence tomography angiography(OCTA)and MP-3 microperimetry.METHODS:Twenty-eight patients(42 eyes)diagnosed with DME were treated with intravitreal injection of aflibercept.The changes in best corrected visual acuity(BCVA),central retinal thickness(CRT),foveal avascular zone(FAZ)area,vessel density of superficial retinal capillary plexus(SVD),vessel density of deep retinal capillary plexus(DVD),mean light sensitivity(MLS),2°fixation rate(P1),4°fixation rate(P2),and other indicators 1mo after treatment were compared;of these,BCVA was conver ted into logarithm of the minimum angle of resolution(logMAR),and the correlation among the factors was analyzed.RESULTS:After treatment,logMAR BCVA was 0.47±0.24,which was significantly better than that before treatment(0.63±0.28,P<0.001).The CRT was 359.21±107.87μm after treatment,which was significantly lower than before treatment(474.10±138.20μm,P<0.001).The FAZ area,SVD,and DVD were not significantly changed after treatment compared with the baseline.MLS was 22.16±4.20 dB after treatment,which was significantly higher than before treatment(19.63±4.23 dB,P<0.001).P2 significantly increased after treatment than before treatment(P=0.007).P1 had no significant change after treatment than before treatment(P=0.086).CONCLUSION:A single intravitreal injection of aflibercept effectively reduces macular edema and improves retinal sensitivity,fixation stability,and visual acuity,possibly without causing significant changes in the retinal vascular condition in a short time.

On the Value of "Wild Play Grounds" in Promoting Local "Carefree Travelling"

'Wild Play Grounds' are the wild places which can attract people to visit.And the 'Wild Play Grounds' are generally the naturally existing places with unique charm,rather than the established tourist attractions or scenic spots.There are no formal organizations for the daily management.Both tickets and clear geographical borders can not be found here.In this research,'Carefree Travelling' is an integrated project of tourism resources in Shandong Province promoted in 2007.Because of their particular characteristics,the 'Wild Play Grounds' have a certain relationship with 'Carefree Travelling',and they are the natural resources of 'Carefree Travelling'.The development of 'Wild Play Grounds' is the further exploitation of the 'Carefree Travelling' resources as well as a better expanding of the tourist market.Relying on the 'Wild Play Grounds',it also has many advantages to develop 'Carefree Travelling',and it will bring good economic and social benefits.Local government should play an important role in developing the 'Wild Play Grounds'.

Research on Children’s Game Activity Design Strategies Based on Embodied Cognition Theory

Edutainment,in the kindergarten education stage,emphasizes the game as the basic activity and combines the content of education with the form of the game,thus it also forms the educational method of gamification teaching.Through investigation and analysis,it is found that the current kindergarten game activity design has the problem of improper combination of educational content and game form.The current kindergarten game activity design has problems such as stereotypes,children’s lack of active learning opportunities in activities,teachers’insufficient theoretical understanding,inappropriate teacher guidance methods,and so on.Embodied cognition theory attaches importance to the important role of the body in the development of cognition,provides new guidance for classroom teaching,and opens up a new path for classroom teaching reform.Based on the perspective of embodied cognition theory,the concept of body and mind integration should be adhered to in kindergarten teaching with games as the basic activity,experiential teaching situation should be created,children’s subjective experience should be respected,and games and interactions should be designed to promote children’s physical and mental participation,thus laying a foundation for the realization of children’s individual freedom,autonomy,and all-round development.Therefore,this paper aims at the existing problems in the current kindergarten gamification teaching and discusses the design strategy of children’s game activities based on embodied cognition theory.

The Application of TBL Using Role Play to Introduce Vocabulary in China's Private Language School

A specific application of task-based learning in teaching vocabulary to young learners and a complete task cycle using role play to present vocabulary in China's private language school would be described in the study. The participants aged between 7 and 9 are thought to be starters according to their language competence in Common European Framework of Reference for language. The rationale for stages in the task cycle will be fully explored with reference to Piaget and Vygotsky's theory in teaching young learners. The advantages of the adoption of TBL with young learners will be illustrated and some possible problems in implementing TBL in China, a representative country of Confucian-heritage culture would also be discussed in the paper. The study indicates that young learners in China are quite welcome this new approach in their English classes, but the targeted learners' age and background information need to be taken into consideration when actually implement this approach.

THE BEST SYSTEM FOR CHINA

It makes more sense to look at which is better for their own people.During a debate comparing Chinese and Western systems of governance,held in Cambridge,Massachusetts,by the American nonprofit educational organization Intercollegiate Studies Institute on April 5,French entrepreneur and Internet influencer Arnaud Bertrand made a case for the suitability of China’s system for promoting the flourishing of its people.Edited excerpts of his presentation follow.

Hydrocarbon accumulation conditions and exploration targets of the Sinian Dengying Formation in the Southeastern Sichuan Basin

No breakthrough has been made in petroleum exploration of the Sinian Dengying Formation in the southeastern Sichuan Basin as the major factors controlling the hydrocarbon accumulation of the Dengying Formation have not been well established,including the development period and distribution of the platform margin,the effectiveness of the source-reservoir combination and the reliability of the Cambrian pre-salt structural trap.Based on the interpretation of seismic data and hydrocarbon-source correlation,the distribution of the platform margin of the Sinian Dengying Formation in the southeastern Sichuan Basin was mapped.Moreover,the gas source rocks of the Dengying Formation were clarified according to geochemical characteristics of fluid inclusions,and the pre-salt structures were further confirmed by seismic forward modeling and experiments of prestack depth migration.Results showed that the sedimentary facies of the 4th member of Dengying Formation in the southeastern Sichuan Basin was platform margin of gentle slope type.The platform margin reservoir of the Dengying Formation and the Lower Cambrian source rocks constitute a favorable source-reservoir combination.The carbon isotope characteristics of gas in fluid inclusions indicate that some of the oil/gas in the Dengying Formation were contributed by the Doushantuo Formation source rocks.As the difference in seismic velocities between carbonate rocks and gypsum/salt beds may cause a reduction in the amplitude of pre-salt structures,the low-amplitude structures identified on current seismic profiles are underestimated instead of overestimated.Accordingly,the Sinian structural traps are confirmed to develop in the deep pre-salt sequences in the low-steep anticline belt,southeastern Sichuan Basin.On the basis of the above new understanding,we propose two types of hydrocarbon migration modes for the Sinian Dengying Formation in southeastern Sichuan Basin,including lateral migration of hydrocarbons generated from the Cambrian Qiongzusi Formation and vertical migration of hydrocarbons derived from the Sinian Doushantuo Formation.Lithologic traps at the platform margin and pre-salt structural traps within the platform are favorable targets for natural gas exploration.

The Protection of Right of Minors to Express Their Opinions in Family Litigations

The right of minors to express their opinions in family litigations refers to minors,who have a certain degree of mental capacity and assertiveness,having the right to express their opinions on the arrangements or decisions related to themselves when the courts handle familial litigation cases involving their interests,and to request the courts hear their opinions.In essence,the right of minors to express their opinions in family litigations belongs to the basic procedural rights of minors as well as judicial beneficiary rights.As for the protection of the right of minors to express their opinions in family litigations,recognizing the status of minors as independent subjects of rights is the logical premise,the procedural guarantee for the rights of the substantive parties involved is the direct cause,and ensuring the best interests of children is the fundamental reason.In order to protect the right of minors to express their opinions in family litigations,China should standardize the mechanisms for judges to hear the opinions of minors directly,improve the mechanisms for family investigators,and establish mechanisms for representing the interests of minors.

Best Practices in Construction 4.0:Catalysts of Digital Innovations(Part I)

Digital transformation in the AEC industry(Architecture,Engineering and Construction)is a key driver to enhance technical innovation in the branch and adds dynamic to all work processes and methods.A more differentiated understanding of the responsible use of innovative technologies aims not only towards increased technical,environmental,educational,societal and gender equality sustainability and more efficient building life cycles but also to recognize the unintended effects such as artificial intelligence(AI).The study is part of a larger primary research on Corporate Digital Responsibility(CDR)in Construction 4.0.This identifies,analyzes and systematically evaluates key factors of a sustainable digital transformation,especially in the traditionally small-scale Construction Industry,in which there can be no standardized procedure.The study uses interdisciplinary literature and data research and expert interviews.The qualitative method enables a critical-reflexive analysis of the key factors of meaningful and sustainable implementation of innovative technologies in Construction.Application examples show possible approaches,some of which are implemented as prototypes and provide guidance for small to medium-sized companies.The study outlines the necessary steps for companies to define their own potential fields of application and find suitable methods.Another aim of the study is to take stock of the acceptance of new technologies by comparing different perspectives from experts.The study results show new perspectives on the transformation of the Construction Industry.They show that Digital Transformation in Construction 4.0 has great potential for an economical,efficient construction life cycle,but requires the responsible,sensible use of innovative technologies.

Best Practices in Construction 4.0-Catalysts of Digital Innovations(Part II)

Part II on Best Practices in Construction 4.0 follows up on the previously published study Part I.This study examines corporate strategies from different angles,defines potential fields of application and works out existing empirical values and trends in the digitization process of the building sector.It highlights the unintended consequences of technological development and offers concrete practical approaches for responsible use.Using the qualitative research method,the study concludes that digital methods,such as Building Information Modelling(BIM)and Digital Twins,and Artificial Intelligence(AI)can add value,significantly reduce resources and increase sustainability.The study is part of a larger primary research on Corporate Digital Responsibility(CDR)in Construction 4.0;it identifies,analyzes and systematically evaluates the pillars of a sustainable digital transformation,especially in the Construction Industry.The holistic,interdisciplinary view of this study aims to provide orientation for small to medium-sized companies(SMEs)developing their individual digital strategy.An outline of the necessary prerequisites but also design options,as they result from the evaluation of expert interviews and literature research,supports companies in the design of Construction 4.0 that is in line with the needs of people,society and the environment and shaping more economically efficient building life cycles.It highlights that digital transformation has also reached the traditionally small-scale AEC industry(small-scale architecture,engineering and construction industry)and catalyzes the variety of innovations.

The Jackson Inequality for the Best L^2-Approximation of Functions on [0,1] with the Weight x

Let L^2（[0, 1], x） be the space of the real valued, measurable, square summable functions on [0, 1] with weight x, and let n be the subspace of L2（[0, 1], x） defined by a linear combination of Jo（μkX）, where Jo is the Bessel function of order 0 and {μk} is the strictly increasing sequence of all positive zeros of Jo. For f ∈ L^2（[0, 1], x）, let E（f, n） be the error of the best L2（[0, 1], x）, i.e., approximation of f by elements of n. The shift operator off at point x ∈[0, 1] with step t ∈[0, 1] is defined by T（t）f（x）=1/π∫0^π f（√x^2 ＋t^2-2xtcosO）dθ The differences （I- T（t））^r/2f = ∑j=0^∞（-1）^j（j^r/2）T^j（t）f of order r ∈ （0, ∞） and the L^2（[0, 1],x）- modulus of continuity ωr（f,τ） = sup{｜｜（I- T（t））^r/2f｜｜：0≤ t ≤τ] of order r are defined in the standard way, where T^0（t） = I is the identity operator. In this paper, we establish the sharp Jackson inequality between E（f, n） and ωr（f, τ） for some cases of r and τ. More precisely, we will find the smallest constant n（τ, r） which depends only on n, r, and % such that the inequality E（f, n）≤ n（τ, r）ωr（f, τ） is valid.

Solve the False-Positive Problem of the Mimic System Based on the Best Mimic Component Set

At present,there is a problem of false positives caused by the too vast mimic scope in mimic transformation technology.Previous studies have focused on the“compensation”method to deal with this problem,which is expensive and cannot fundamentally solve it.This paper provides new insights into coping with the situation.Firstly,this study summarizes the false-positive problem in the mimic transformation,analyzes its possible harm and the root causes.Secondly,three properties about the mimic scope are proposed.Based on the three properties and security quantification technology,the best mimic component set theory is put forward to solve the false-positive problem.There are two algorithms,the supplemental method and the subtraction method.The best mimic component set obtained by these two algorithms can fundamentally solve the mimic system’s false-positive problem but reduce the cost of mimic transformation.Thus make up for the lack of previous researches.