Swarming Responsive Photonic Nanorobots for Motile-Targeting Microenvironmental Mapping and Mapping-Guided Photothermal Treatment

Micro/nanorobots can propel and navigate in many hard-to-reach biological environments,and thus may bring revolutionary changes to biomedical research and applications.However,current MNRs lack the capability to collectively perceive and report physicochemical changes in unknown microenvironments.Here we propose to develop swarming responsive photonic nanorobots that can map local physicochemical conditions on the fly and further guide localized photothermal treatment.The RPNRs consist of a photonic nanochain of periodically-assembled magnetic Fe_(3)O_(4)nanoparticles encapsulated in a responsive hydrogel shell,and show multiple integrated functions,including energetic magnetically-driven swarming motions,bright stimuli-responsive structural colors,and photothermal conversion.Thus,they can actively navigate in complex environments utilizing their controllable swarming motions,then visualize unknown targets(e.g.,tumor lesion)by collectively mapping out local abnormal physicochemical conditions(e.g.,pH,temperature,or glucose concentra-tion)via their responsive structural colors,and further guide external light irradiation to initiate localized photothermal treatment.This work facilitates the development of intelligent motile nanosensors and versatile multifunctional nanotheranostics for cancer and inflam-matory diseases.

Development of a location-weighted landscape contrast index based on the minimum hydrological response unit

The changing patterns of watersheds in a landscape, driven by human activities, play an important role in non-point source pollution processes. This paper aims to improve the location-weighted landscape contrast index using remote sensing and GIS technology to account for the effects of scale and ecological processes. The hydrological response unit(HRU) with a single land use and soil type was used as the smallest unit. The relationship between the landscape index and typical ecological processes was established by describing the influence of the landscape pattern on non-point source pollution. To verify the research method, this paper used the Yanshi River basin as a study area. The results showed that the relative intensity of non-point source pollution in different regions of the watershed and the location-weighted landscape contrast index based on the minimum HRU can qualitatively reflect the risk of regional nutrient loss.

An evaluation of the role played by remote sensing technology following the World Trade Center attack

Remote sensing technology has been widely recognized for contributing to emergency response efforts after the World Trade Center attack on September 11th, 2001. The need to coordinate activities in the midst of a dense, yet relatively small area, made the combination of imagery and mapped data strategically useful. This paper reviews the role played by aerial photography, satellite imagery, and LIDAR data at Ground Zero. It examines how emergency managers utilized these datasets, and identifies significant problems that were encountered. It goes on to explore additional ways in which imagery could have been used, while presenting recommendations for more effective use in future disasters and Homeland Security applications. To plan adequately for future events, it was important to capture knowledge from individuals who responded to the World Trade Center attack. In recognition, interviews with key emergency management and geographic information system (GIS) personnel provide the basis of this paper. Successful techniques should not be forgotten, or serious problems dismissed. Although widely used after September 11th, it is important to recognize that with better planning, remote sensing and GIS could have played an even greater role. Together with a data acquisition timeline, an expanded discussion of these issues is available in the MCEER/NSF report “Emergency Response in the Wake of the World Trade Center Attack; The Remote Sensing Perspective” (Huyck and Adams, 2002) Keywords World Trade Center (WTC) - terrorism - emergency response - emergency management - ground zero - remote sensing - emergency operations - disasters - geographic information systems (GIS) - satellite imagery - synthetic aperture radar (SAR) - light detection and ranging imagery (LIDAR)

On the issue of erroneous translation in the Chinese version of The Da Vinci code

With eight typical examples, this paper discusses the erroneous translation in the Chinese version of The Da Vinci code, points out the possible reasons and suggests the importance of faithfulness and that of sense of responsibility.

Sense of CommuniW Responsibility as a Determinant of Corporate Responsibility

Research on the social value of the bus industry in Australia revealed an inconsistency in findings between qualitative and quantitative results in relation to the nature of a bus operator＇s interaction with the community where they provide a transport service. As part of a larger research project that surveyed bus operators about their corporate social responsibility, bivariate analysis found that the responses to the embedded Sense of Community Index （SOCI） did not provide a predictor of the extent of a bus operator＇s community interaction or determinant of Corporate Responsibility （CR）. However, qualitative comments in the survey suggested that bus operators did display strong positive feelings about their community. Published after the data collection stage was completed, the Sense of Community Responsibility Index （SOCRI） appeared to be a better fit than SOCI to explain the nature of bus operator＇s interaction with their community. Rather than drawing on community resources, the interaction was shown to be one of leaderships on the part of the operator. Further examination of this relationship using the SOCR would test this finding.

The Avenue of Sphinxes： Restoration of a Legend

The redevelopment of historic cities is often challenged by intricate--and in many cases contradictory--missions. From one side, there is the urge to comprehensively preserve cultural resources. At the same time, opportunities of economic growth should be made available and needs of contemporary living maintained and nourished. The main aim of this paper is to reconcile probable incompatibilities between such missions through promoting ＂sensitive＂ redevelopment approaches in historic cities. The paper focuses on the city of Luxor, Egypt with its immensely capturing yet quite undermined legend： the Avenue of Sphinxes. In Luxor, the injection of nonintrusive interventions presents itself as a highly potential candidate in protecting and enhancing the experience of the avenue while meeting contemporary needs of living. Adopting less sensitive development approaches can lead the quality of experiencing the whole city to be worsened for the increasing numbers of tourists and locals.

The Influence Factors on Regret Emotion Responsibility and Perceived Control

When people realize or imagine that ＂if you have not taken the same choices as before, the result will be better＂, which kind of experience is called a regret emotion. The purpose of this study is to prove the relationship between regret emotions and a sense of responsibility and control. The results show that the individual＇s sense of responsibility and regret that there is a positive correlation and there is a negative correlation between the control and regret, which is not match the previous part of the study so as to be further explored. At the same time, we found that the regret tendencies in the personality can be explained as some of the regret experiencing in the specific situation. When people realize or imagine that ＂if the choice is not the same as before that things are getting better now＂, they will feel regret.

Emergency Seismic Damage Assessment of the M_S8.0 Great Wenchuan Earthquake Based on Remote Sensing Imagery

The fast processing, seismic damage data extraction and loss evaluation from RS imagery acquired immediately after a destructive earthquake occurs, are important means for compen- sating the insufficiency of seismic damage information from ground-based investigations and provide an important basis for emergency command and rescue. The paper introduces the method of emergency seismic damage assessment using remote sensing data and its application to the great Wenchuan earthquake of magnitude 8.0 occurring in southwest Sichuan Province on May 12, 2008. The practical effectiveness of the method is also evaluated in the paper.

Solvent-free synthesis of hierarchical Tb^(3+)-doped Yttrium benzene-1,3,5-tricarboxylate metal organic framework nanosheets for fast and highly sensitive fluorescence detection of Fe3+and Cr2O72−ions

Controllable synthesis of luminescent metal-organic frameworks (MOFs) having the merits of ease preparation, outstanding sensitivity and stability is of great significance for exploring their efficient sensing applications. Herein, we report a hierarchical terbium-doped yttrium-benzene-1,3,5-tricarboxylate MOF nanosheet via solvent-free synthetic strategy with a topological structure of MIL-78. The fluorescence property of the hierarchical Tb^(3+)-doped Y-based MOF nanosheets can be tuned by adjusting the molar ratio of Tb^(3+) to Y^(3+) ions, and the Tb_(0.5)Y_(0.5)-MOF nanosheet-like morphology with the optimum characteristic Tb^(3+) ion green emission exhibited great potential acting as fluorescence probe for highly sensitive Fe^(3+) and Cr_(2)O_(7)^(2−) detection. The Tb^(3+)-doped Y-MOF nanosheets show a fast response time of less than 1 s for Fe^(3+) ions. They also have low detection limits of 0.40 and 0.26 µM toward Fe^(3+) and Cr_(2)O_(7)^(2−) ions, respectively, as well as excellent stability. This work paves the way to explore intriguing hierarchical MOF-based luminescent materials for efficient fluorescence sensing applications.

The unique immune evasion mechanisms of the mpox virus and their implication for developing new vaccines and immunotherapies

Mpox is an infectious and contagious zoonotic disease caused by the mpox virus(MPXV),which belongs to the genus Orthopoxvirus.Since 2022,MPXV has posed a significant threat to global public health.The emergence of thousands of cases across the Western Hemisphere prompted the World Health Organization to declare an emergency.The extensive coevolutionary history of poxviruses with humans has enabled these viruses to develop sophisticated mechanisms to counter the human immune system.Specifically,MPXV employs unique immune evasion strategies against a wide range of immunological elements,presenting a considerable challenge for treatment,especially following the discontinuation of routine smallpox vaccination among the general population.In this review,we start by discussing the entry of the mpox virus and the onset of early infection,followed by an introduction to the mechanisms by which the mpox virus can evade the innate and adaptive immune responses.Two caspase-1 inhibitory proteins and a PKR escape-related protein have been identified as phylogenomic hubs involved in modulating the immune environment during the MPXV infection.With respect to adaptive immunity,mpox viruses exhibit unique and exceptional T-cell inhibition capabilities,thereby comprehensively remodeling the host immune environment.The viral envelope also poses challenges for the neutralizing effects of antibodies and the complement system.The unique immune evasion mechanisms employed by MPXV make novel multi-epitope and nucleic acid-based vaccines highly promising research directions worth investigating.Finally,we briefly discuss the impact of MPXV infection on immunosuppressed patients and the current status of MPXV vaccine development.This review may provide valuable information for the development of new immunological treatments for mpox.

Benchmarking dynamic properties of structures using non-contact sensing

Non-contact sensing can be a rapid and convenient alternative for determining structure response compared to conventional instrumentation.Computer vision has been broadly implemented to enable accurate non-contact dynamic response measurements for structures.This study has analyzed the effect of non-contact sensors,including type,frame rate,and data collection platform,on the performance of a novel motion detection technique.Video recordings of a cantilever column were collected using a high-speed camera mounted on a tripod and an unmanned aerial system(UAS)equipped with visual and thermal sensors.The test specimen was subjected to an initial deformation and released.Specimen acceleration data were collected using an accelerometer installed on the cantilever end.The displacement from each non-contact sensor and the acceleration from the contact sensor were analyzed to measure the specimen′s natural frequency and damping ratio.The specimen′s first fundamental frequency and damping ratio results were validated by analyzing acceleration data from the top of the specimen and a finite element model.

Hepcidin levels in hereditary hyperferritinemia:Insights into the iron-sensing mechanism in hepatocytes

AIM:To study the role of hepcidin in hereditary hyperferritinemia cataract syndrome(HHCS). METHODS:Six patients from two families with HHCS, confirmed by genetic analysis showing A to G mutation at position+40 in the L-ferritin gene,were recruited to undergo serum hepcidin and prohepcidin measurements using radioimmunoassay and enzyme linked immunoassay,respectively,and measurements were compared with levels in serum from 25 healthy volunteers(14 females),mean age 36±11.9 years.RESULTS:The serum hepcidin and prohepcidin levels in patients with HHCS were 19.1±18.6 and 187± 120.9 ng/mL,respectively.Serum ferritin was 1716.3± 376μg/L.Liver biopsy in one patient did not show any evidence of iron overload.Serum hepcidin and prohepcidin values in healthy controls(HCs)were 15.30±15.71 and 236.88±83.68 ng/mL,respectively,while serum ferritin was 110±128.08μg/L.There was no statistical difference in serum hepcidin level between the two cohorts(19.1±18.6 ng/mL vs 15.30±15.71 ng/mL,P= 0.612)using two-tailed t-test. CONCLUSION:Serum hepcidin levels in HHCS patients is similar to that in HCs.Our study suggests that circulating ferritin is not a factor influencing hepcidin synthesis and does not have a role in the iron-sensing mechanism in hepatocytes.

Impact of State-Owned Capital Participation on ESG Performance of Private Enterprises

As global investors and stakeholders increasingly prioritize environmental,social,and governance(ESG)performance,corporate social responsibility and sustainability have become crucial factors in determining corporate success.In the context of China’s robust economy,the involvement of state-owned capital exerts a profound impact on the ESG performance of private enterprises.This paper,starting from the perspective of ESG,analyzes how state-owned capital participation influences the ESG performance of private enterprises.Additionally,it proposes recommendations for the involvement of state-owned enterprises in private enterprises,aiming to foster the sustainable development of private enterprises and enhance their social responsibility.

铸牢中华民族共同体意识视域下高校和美校园建设路径探析

社会主义核心价值观与铸牢中华民族共同体意识深度契合,并以社会主义核心价值观引领铸牢中华民族共同体意识,正确指引学生健康成长和全面成才,建设和美校园。新时代铸牢中华民族共同体意识中,校园文化建设在融入社会主义核心价值观时面临现实挑战,因此,本文提出解决问题的方案,即从夯实校园物质文化、健全校园制度文化、强化校园精神文化角度,实现社会主义核心价值观实践环节的文化力量、人格完善、价值引导目标,以此来更有效地引领学生铸牢中华民族共同体意识。

护士心理资本类别及与团队工作重塑的关系

目的探讨护士心理资本的潜在类别及与团队工作重塑的关系,为制订针对性的干预方案提供参考。方法采用一般资料调查表、护士心理资本量表、护士团队工作重塑量表,对山东省5所三级甲等综合医院的465名护士进行调查。结果护士心理资本得分(153.63±23.00)分。潜在剖面分析显示,心理资本可分为高情商-高责任感型(44.1%)、心理资本中等型(36.8%)、低韧性-低自信型(19.1%)3个类别。分层多元线性回归分析显示,控制混杂因素后,心理资本类别是护士团队工作重塑的影响因素(P<0.05),可解释23.5%的变异量。结论护士心理资本处于较高水平,但具有异质性,心理资本类别是其团队工作重塑的影响因素。护理管理者可针对心理资本的潜在类别采取针对性干预措施,提升护士的团队工作重塑行为,以激发团队活力、改善护理服务质量。

容错动态性如何提升员工适应性绩效?——一个有调节的中介模型

员工适应性绩效是企业应对环境变化的重要基础,而容错动态性为解释员工适应性绩效提供了新视角。文章基于情绪事件理论、自我调节理论和资源保存理论,以306名科技型企业在职员工为调研对象,明晰了容错动态性对员工适应性绩效影响的路径和边界条件。结果表明:容错动态性对员工适应性绩效具有显著的正向影响;元认知能力在容错动态性与员工适应性绩效之间发挥中介作用;任务责任心调节容错动态性与元认知能力之间的关系,并进一步调节了容错动态性通过元认知能力对员工适应性绩效起的间接作用。研究从组织情绪视角提出了容错动态性是员工适应性绩效的另一影响因素,为企业提升员工适应性绩效提供新方法。

世界史教学中铸牢中华民族共同体意识的理念与实践

历史教学是铸牢中华民族共同体意识的重要途径,世界史教学有助于从“远距离”“宽视野”的角度增强学生的中华民族认同感、自豪感和责任感:使学生理解中华民族在世界文明舞台上从自在到自觉的发展过程,认识中华文明对世界文明发展作出的巨大贡献,并且自觉承担起为中华民族伟大复兴而奋斗的重任。在世界史教学中,教师可以通过课堂讲授、师生讨论、读书汇报等方式将中华民族共同体意识有机融入课前、课中和课后的多个环节,充分发挥历史学科增强共同记忆、培养共同情怀的重要作用。

论自然主义道德责任问题的困境——对功能规范型归责理论的再思考

基于自然化的“功能”概念来处理道德责任问题是颇为切合当代主流世界观的一种进路。沿着这一思路,晓非就“否决功能如何说明自主行为中的自由感”“如何基于功能式同一性标准应对操纵难题”与“‘功能规范型’模型如何说明道德归责的规范性”等问题展开了颇有新意的探讨。围绕这三个主题,还需要进一步探讨以下观点:升级版的否决功能假说本身存在着削弱自由感的风险;借助功能同一性标准的思路切中了操纵难题的一个当代启示,即公正的归责需要清晰锁定表面行动背后的核心决策来源;当前版本的“功能规范型”归责理论尚未彻底摆脱实用主义困境。

基于波谱响应特征的雄安新区农田土壤重金属含量反演

分析并监测雄安新区农田土壤污染状况,对于保障粮食安全、建设绿色雄安具有重要意义。该研究以雄安新区为研究区,基于多源遥感数据珠海一号(Zhuhai-1)OHS数据、哨兵二号(Sentinel-2)L2A级数据的波谱响应特征及实地测得的农田土壤重金属含量数据,在对土壤重金属含量单因子与多因子污染评价的基础上,筛选出3种超标的农田重金属元素铅(Pb)、铜(Cu)、锌(Zn),采用偏最小二乘回归方法(partial least squares regression,PLSR)建立农田土壤重金属含量反演模型。利用Zhuhai-1提取土壤样本点的原始光谱反射率以及4种变换后的光谱反射率,Sentinel-2提取7种对重金属胁迫敏感的植被指数,将其与3种土壤重金属含量作相关性分析,筛选出敏感波段与植被指数,即波谱响应特征,构建土壤重金属含量反演模型。结果表明,3种模型整体反演精度较为优良,Pb含量反演模型决定系数(determination coefficient,R^(2))为0.490,均方根误差(root mean squared error,RMSE)为4.66 mg/kg,平均绝对值误差(mean absolute error,MAE)为1.92 mg/kg;Cu含量反演模型R^(2)为0.491,RMSE为16.85 mg/kg,MAE为3.69 mg/kg;Zn含量反演模型R^(2)为0.664,RMSE为20.63 mg/kg,MAE为9.36 mg/kg。将该模型应用于雄安新区农田区域,得到大部分农田土壤中Pb含量均未超过风险筛选标准,在研究区西南部、西部部分区域Cu含量超过土壤污染风险筛选值,同时在研究区西部、西南部Zn污染较严重,雄安新区东南部部分农田有Zn零星分布,其他区域Cu和Zn含量未超过国家土壤污染风险管控值。因此,利用多源遥感数据波谱响应特征反演土壤重金属Pb、Cu和Zn含量,能够快速准确地实现对雄安新区土壤重金属污染情况的调查,同时为大面积土壤重金属含量监测提供解决方案。