Significant controversies exist with regards to the optimal management of lateral pelvic lymph nodes metastases(mLLN)in patients with low rectal cancer.The differing views held by Japanese and Western clinicians on th...Significant controversies exist with regards to the optimal management of lateral pelvic lymph nodes metastases(mLLN)in patients with low rectal cancer.The differing views held by Japanese and Western clinicians on the management of mLLN have been well documented.However,the adequacy of pelvic lymph node dissection(PLND)or neoadjuvant chemoradiation(NACRT)alone in addition to total mesorectal excision(TME)have recently come into question,due to the relatively high incidence of lateral local recurrences following PLND and TME,or NACRT and TME alone.Recently,a more selective approach to PLND has been suggested,involving a combination of neoadjuvant therapy,followed by PLND only to patients in whom the oncological benefit is likely to outweigh the risk of potential adverse events.A number of studies have attempted to retrospectively identify certain nodal characteristics on preoperative imaging,such as nodal size,appearance,and size reduction following neoadjuvant therapy.However,no consensus has been reached regarding the optimal criteria for a selective approach to PLND,partly due to the heterogeneity and retrospective nature of most of these studies.This review aims to provide an overview of recent evidence with regards to the diagnostic challenges,considerations for,and outcomes of the current management strategies for mLLN in rectal cancer patients.展开更多
In this study we describe an FEM-based methodology to solve the coupled fluid-structure problem due to squeeze film effects present in vibratory MEMS devices, such as resonators, gyroscopes, and acoustic transducers. ...In this study we describe an FEM-based methodology to solve the coupled fluid-structure problem due to squeeze film effects present in vibratory MEMS devices, such as resonators, gyroscopes, and acoustic transducers. The aforementioned devices often consist of a plate-like structure that vibrates normal to a fixed substrate, and is generally not perfectly vacuum packed. This results in a thin film of air being sandwiched between the moving plate and the fixed substrate, which behaves like a squeeze film offering both stiffness and damping. Typically, such structures are actuated electro-statically, necessitating the thin air gap for improving the efficiency of actuation and the sensitivity of detection. To accurately model these devices the squeeze film effect must be incorporated. Extensive literature is present on mod- eling squeeze film effects for rigid motion for both perforated as well as non-perforated plates. Studies which model the plate elasticity often use approximate mode shapes as input to the 2D Reynolds Equation. Recent works which try to solve the coupled fluid elasticity problem, report iterative FEM-based solution strategies for the 2D Reynolds Equation coupled with the 3D elasticity Equation. In this work we present a FEM-based single step solution for the coupled problem at hand, using only one type of element (27 node 3D brick). The structure is modeled with 27 node brick elements of which the lowest layer of nodes is also treated as the fluid domain (2D) and the integrals over fluid domain are evaluated for these nodes only. We also apply an electrostatic loading to our model by considering an equivalent electro-static pressure load on the top surface of the structure. Thus we solve the coupled 2D-fluid-3D-structure problem in a single step, using only one element type. The FEM results show good agreement with both existing analytical solutions and published experimental data.展开更多
Abstract A comprehensive three-dimensional model of droplet-gas flow was presented to study the evolution of spray in the effervescent atomization spray with an impinging plate. For gas phase, the N-S equation with t...Abstract A comprehensive three-dimensional model of droplet-gas flow was presented to study the evolution of spray in the effervescent atomization spray with an impinging plate. For gas phase, the N-S equation with the κ-ε turbulence model was solved, considering two-way coupling interaction between droplets and gas phase. Dispersed droplet phase is modeled as Lagrangian entities, accounting for the physics of droplet generation from primary and secondary breakup, droplet collision and coalescence, droplet momentum and heat transfer. The mean size and sta- tistical distribution of atomized droplets at various nozzle-to-plate distances were calculated. Some simulation resuits were compared well with experimental data. The results show that the existence of the impinging plate has a pronounced influence on the droplet mean size, size distribution and the droplet spatial distribution. The air-to-liquid ratio has obvious effects on the droplet size and distribution.展开更多
A new theory and method that differs from the tradition-al single plated weft - knitting theory and method hasbeen expounded after theoretical analyzing and experi-mental proving. If the new method is used when platin...A new theory and method that differs from the tradition-al single plated weft - knitting theory and method hasbeen expounded after theoretical analyzing and experi-mental proving. If the new method is used when platingstitch is knitted on large diameter weft knitting machine,the thorny problem of long standing that ground yarn iseasy to appear on the face side of fabric is solved. Thenew method, i.e, the production of physical ability oftraining uniform for serviceman has been used.展开更多
In this paper the significance analysis has been made of the factors influencing the yarn appearing of single plated weft-knit fabrics knitted on large diameter machine by a mathematical statistical method. By means o...In this paper the significance analysis has been made of the factors influencing the yarn appearing of single plated weft-knit fabrics knitted on large diameter machine by a mathematical statistical method. By means of orthogonal test and variance analysis, it is known that the feeding tension is the significant factor influencing the yarn appearance and the ground yarn tension should be larger than the face yarn tension. Through comparison, it is also known that the drawing off force should be regulated suitably, the carrier should be near the first closed needle, and the sinker should be out late slightly.展开更多
According to the experimental data of the orifice discharge coefficient for the flow through a vertical sharp-edged orifice obtained in the previous study of this work,a theoretical criterion for flow mechanisms of sm...According to the experimental data of the orifice discharge coefficient for the flow through a vertical sharp-edged orifice obtained in the previous study of this work,a theoretical criterion for flow mechanisms of small orifice（viz.thick-walled orifice and nozzle） and large orifice（viz.thin-walled orifice） was proposed based on the ratio of orifice diameter to plate thickness.It can help explain the dissipation of the mechanical energy loss in the flow process for the two flow mechanisms under different operating regimes.The main parameters such as orifice diameter,plate thickness and liquid head were correlated,and a semi-empirical model for orifice coefficient and an empirical model with high precision at the stable region were developed.展开更多
文摘Significant controversies exist with regards to the optimal management of lateral pelvic lymph nodes metastases(mLLN)in patients with low rectal cancer.The differing views held by Japanese and Western clinicians on the management of mLLN have been well documented.However,the adequacy of pelvic lymph node dissection(PLND)or neoadjuvant chemoradiation(NACRT)alone in addition to total mesorectal excision(TME)have recently come into question,due to the relatively high incidence of lateral local recurrences following PLND and TME,or NACRT and TME alone.Recently,a more selective approach to PLND has been suggested,involving a combination of neoadjuvant therapy,followed by PLND only to patients in whom the oncological benefit is likely to outweigh the risk of potential adverse events.A number of studies have attempted to retrospectively identify certain nodal characteristics on preoperative imaging,such as nodal size,appearance,and size reduction following neoadjuvant therapy.However,no consensus has been reached regarding the optimal criteria for a selective approach to PLND,partly due to the heterogeneity and retrospective nature of most of these studies.This review aims to provide an overview of recent evidence with regards to the diagnostic challenges,considerations for,and outcomes of the current management strategies for mLLN in rectal cancer patients.
文摘In this study we describe an FEM-based methodology to solve the coupled fluid-structure problem due to squeeze film effects present in vibratory MEMS devices, such as resonators, gyroscopes, and acoustic transducers. The aforementioned devices often consist of a plate-like structure that vibrates normal to a fixed substrate, and is generally not perfectly vacuum packed. This results in a thin film of air being sandwiched between the moving plate and the fixed substrate, which behaves like a squeeze film offering both stiffness and damping. Typically, such structures are actuated electro-statically, necessitating the thin air gap for improving the efficiency of actuation and the sensitivity of detection. To accurately model these devices the squeeze film effect must be incorporated. Extensive literature is present on mod- eling squeeze film effects for rigid motion for both perforated as well as non-perforated plates. Studies which model the plate elasticity often use approximate mode shapes as input to the 2D Reynolds Equation. Recent works which try to solve the coupled fluid elasticity problem, report iterative FEM-based solution strategies for the 2D Reynolds Equation coupled with the 3D elasticity Equation. In this work we present a FEM-based single step solution for the coupled problem at hand, using only one type of element (27 node 3D brick). The structure is modeled with 27 node brick elements of which the lowest layer of nodes is also treated as the fluid domain (2D) and the integrals over fluid domain are evaluated for these nodes only. We also apply an electrostatic loading to our model by considering an equivalent electro-static pressure load on the top surface of the structure. Thus we solve the coupled 2D-fluid-3D-structure problem in a single step, using only one element type. The FEM results show good agreement with both existing analytical solutions and published experimental data.
基金Supported by the Major Program of the National Natural Science Foundation of China （10632070）
文摘Abstract A comprehensive three-dimensional model of droplet-gas flow was presented to study the evolution of spray in the effervescent atomization spray with an impinging plate. For gas phase, the N-S equation with the κ-ε turbulence model was solved, considering two-way coupling interaction between droplets and gas phase. Dispersed droplet phase is modeled as Lagrangian entities, accounting for the physics of droplet generation from primary and secondary breakup, droplet collision and coalescence, droplet momentum and heat transfer. The mean size and sta- tistical distribution of atomized droplets at various nozzle-to-plate distances were calculated. Some simulation resuits were compared well with experimental data. The results show that the existence of the impinging plate has a pronounced influence on the droplet mean size, size distribution and the droplet spatial distribution. The air-to-liquid ratio has obvious effects on the droplet size and distribution.
文摘A new theory and method that differs from the tradition-al single plated weft - knitting theory and method hasbeen expounded after theoretical analyzing and experi-mental proving. If the new method is used when platingstitch is knitted on large diameter weft knitting machine,the thorny problem of long standing that ground yarn iseasy to appear on the face side of fabric is solved. Thenew method, i.e, the production of physical ability oftraining uniform for serviceman has been used.
文摘In this paper the significance analysis has been made of the factors influencing the yarn appearing of single plated weft-knit fabrics knitted on large diameter machine by a mathematical statistical method. By means of orthogonal test and variance analysis, it is known that the feeding tension is the significant factor influencing the yarn appearance and the ground yarn tension should be larger than the face yarn tension. Through comparison, it is also known that the drawing off force should be regulated suitably, the carrier should be near the first closed needle, and the sinker should be out late slightly.
基金supported by the National Natural Science Foundation of China(20806090)
文摘According to the experimental data of the orifice discharge coefficient for the flow through a vertical sharp-edged orifice obtained in the previous study of this work,a theoretical criterion for flow mechanisms of small orifice（viz.thick-walled orifice and nozzle） and large orifice（viz.thin-walled orifice） was proposed based on the ratio of orifice diameter to plate thickness.It can help explain the dissipation of the mechanical energy loss in the flow process for the two flow mechanisms under different operating regimes.The main parameters such as orifice diameter,plate thickness and liquid head were correlated,and a semi-empirical model for orifice coefficient and an empirical model with high precision at the stable region were developed.
