Effects of Continuous Precision Nursing Model on Knowledge, Attitudes, and Practices (KAP) Behavior and Cardiac Function in Patients after Percutaneous Coronary Angiography and Stent Implantation

Objective:To explore the impact of a continuous precision nursing model on patients’Knowledge,Attitudes,and Practices(KAP)and cardiac function during the nursing process of patients undergoing percutaneous coronary angiography and stent implantation.Methods:Ninety patients who underwent percutaneous coronary angiography and stent implantation in our hospital from April 2022 to April 2023 were selected and randomly divided into the control group(45 cases),in which routine nursing support was carried out during the treatment process,and the observation group(45 cases),in which continuous precision nursing model was carried out during the treatment process.Comparisons were made between the two groups of patients on their KAP,cardiac function,and quality of life during recovery.Results:There was no difference in the left ventricular ejection fraction(LVEF),cardiac output(CO),and cardiac index(CI)levels before intervention.After the intervention,the levels of cardiac function in the observation group were higher than those of the control group(P<0.05).There was no difference in the Exercise of Self-Care Agency(ESCA)self-care ability scale scores before the intervention.After the intervention,the observation group had higher ESCA scores than the control group(P<0.05).Conclusion:Implementation of a continuous precision nursing model in the care of patients undergoing percutaneous coronary angiography and stent implantation improved the patient’s cardiac function,and KAP,and promoted recovery.

Distribution and differentiation of bone marrow-derived mesenchymal stem cells in vivo after intraperitoneal and tail vein injection into rats in the recovery phase of stroke: Which path is better?

BACKGROUND： Stereotactic injection （striatum or lateral ventricle） and vascular injection （ tail vein or carotid artery） are now often used in cellular therapy for cerebral infarction. Stereotactic injection can accurately deliver cells to the infarct area, but requires a stereotactic device and causes secondary trauma; vascular injection is easy and better for host neurological deficit recovery, but can cause thrombosis. OBJECTIVE： To compare the therapeutic potential of adult bone marrow-derived mesenchymal stem cells （BMSCs） transplantation by intraperitoneal versus intravenous administration to cerebral ischemic rats. DESIGN, TIME AND SE＇B＇ING： A randomized controlled animal experiment was performed at the Cell Room and Pathology Laboratory, Brain Hospital Affiliated to Nanjing Medical University from November 2007 to September 2008. MATERIALS： BMSCs were derived from 20 healthy Sprague-Dawley rats aged 4-6 weeks. METHODS： Forty-five adult middle cerebral artery occlusion （MCAO） rats were randomly divided into control, intravenous and intraperitoneal injection groups, with 15 rats in each group. At 21 days after modeling, rats in the control group received 1 mL of 0.01 mol/L phosphate buffered saline via tail vein injection and each experimental rat received 4 x 106 BMSCs labeled by bromodeoxyuridine （BrdU） via intravenous or intraperitoneal injection. MAIN OUTCOME MEASURES： Angiogenin expression and survival of transplanted cells were measured by immunohistochemical staining of brain tissue in infarction hemisphere at 7, 14 or 21 days after BMSC transplantation. Co-expression of BrdU/microtubule-associated protein 2 or BrdU/glial fibrillary acidic protein was observed by double-labeled immunofluorescence of cerebral cortex. Evaluation of nerve function adhesion-removal test was performed on the 14 or 21 days after BMSCs treatment. using the neurological injury severity score and the 1st and 21st day before and after MCAO, and at 3, 7 RESULTS： Angiogenin-positive new vessels were distributed in the bilateral striatum, hippocampus and cerebral cortex of each group of rats at each time point, most markedly in the intravenous injection group. There were significantly more BrdU-positive cells in the intravenous injection group than in the intraperitoneal injection group （P 〈 0.01）. Co-expression of BrdU/ microtubule-associated protein 2 or BrdU/glial fibrillary acidic protein were almost only seen in the intravenous group by fluorescence microscopy. After transplantation, BMSCs significantly restored nerve function in rats, particularly in the intravenous injection group. CONCLUSION： BMSCs were able to enter brain tissue via the tail vein or peritoneal injection and improve neurological function by promoting the regeneration of nerves and blood vessels in vivo, more effectively after intravenous than intraperitoneal injection.

CONSTRUCTION OF SOME KIESSWETTER-LIKE FUNCTIONS-THE CONTINUOUS BUT NON-DIFFERENT-IABLE FUNCTION DEFINED BY QUINARY DECIMAL

In this paper, we construct some continuous but non-differentiable functions defined by quinary dec-imal, that are Kiesswetter-like functions. We discuss their properties, then investigate the Hausdorff dimensions of graphs of these functions and give a detailed proof.

On Applications of Generalized Functions in the Discontinuous Beam Bending Differential Equations

This paper discusses the mathematical modeling for the mechanics of solid using the distribution theory of Schwartz to the beam bending differential Equations. This problem is solved by the use of generalized functions, among which is the well known Dirac delta function. The governing differential Equation is Euler-Bernoulli beams with jump discontinuities on displacements and rotations. Also, the governing differential Equations of a Timoshenko beam with jump discontinuities in slope, deflection, flexural stiffness, and shear stiffness are obtained in the space of generalized functions. The operator of one of the governing differential Equations changes so that for both Equations the Dirac Delta function and its first distributional derivative appear in the new force terms as we present the same in a Euler-Bernoulli beam. Examples are provided to illustrate the abstract theory. This research is useful to Mechanical Engineering, Ocean Engineering, Civil Engineering, and Aerospace Engineering.

Dynamic Systems of Shifts in the Space of Piece-Wise Continuous Functions

In this paper we embark on the study of Dynamic Systems of Shifts in the space of piece-wise continuous functions analogue to the known Bebutov system. We give a formal definition of a topological dynamic system in the space of piece-wise continuous functions and show, by way of an example, stability in the sense of Poisson discontinuous function. We prove that a fixed discontinuous function, f, is discontinuous for all its shifts, whereas the trajectory of discontinuous function is not a compact set.

Efficacy of Ulinastatin Combined with Continuous Renal Replacement Therapy in the Treatment of Sepsis Acute Kidney Injury and Its Effects on Systemic Inflammation, Immune Function and miRAN Expression

Objective: To research the effectiveness of ulinastatin in combination with continuous renal replacement therapy in treating sepsis acute kidney injury and its effect on systemic inflammation, immune function and miRAN expression. Methods: The 84 patients who were diagnosed with sepsis complicated by acute kidney injury in our hospital between May 2020 and June 2022 were chosen and randomly assigned to the study group (n = 42) and the control group (n = 42). Ulinastatin in combination with continuous renal replacement therapy was administered to the study group, whereas the control group was administered with continuous renal replacement therapy alone. Both groups’ clinical effects were observed. The levels of blood urea nitrogen (BUN), serum creatinine (SCr), tumor necrosis factor-α (TNF-α), high sensitivity Creactive protein (hs-CRP), vascular cell adhesion molecule-1 (VCAM-1), IgG, IgA, IgM, expression levels of miR-233 and miR-10a were compared among both the groups, pre-, and post-treatment. Results: The study group’s overall effectiveness rate was higher that is 95.24%, in comparison to the control group’s 78.57%, and this difference was statistically significant (P α, hs-CRP, VCAM-1, and miR-233 and miR-10a expression levels in both the study and control groups were decreased, however, the study group had reduced levels in comparison to the control group, with statistically significant differences (P P Conclusion: Ulinastatin in combination with continuous renal replacement therapy for treating sepsis acute kidney injury exhibits a positive effect and can significantly improve the systemic inflammation and immune function in patients.

Effect of continuous nursing on treatment compliance and side effect management of coronary heart disease

BACKGROUND There are relatively few studies on continuing care of coronary heart disease(CHD),and its research value needs to be further clarified.AIM To investigate the effect of continuous nursing on treatment compliance and side effect management in patients with CHD.METHODS This is a retrospective study with patients from January 2021 to 2023.The study was divided into two groups with 30 participants in each group.Self-rating anxiety scale(SAS)and Self-rating depression scale(SDS)were used to assess patients'anxiety and depression,and medical coping questionnaire was used to assess patients'coping styles.The pelvic floor dysfunction questionnaire(PFDI-20)was used to assess the status of pelvic floor function,including bladder symptoms,intestinal symptoms,and pelvic symptoms.RESULTS SAS score decreased from 57.33±3.01before treatment to 41.33±3.42 after treatment,SDS score decreased from 50.40±1.45 to 39.47±1.57.The decrease of these two indexes was statistically significant(P<0.05).PFDI-20 scores decreased from the mean 16.83±1.72 before treatment to 10.47±1.3the mean after treatment,which was statistically significant(P<0.05).CONCLUSION The results of this study indicate that pioneering research in continuous care of CHD has a positive impact on improving patients'treatment compliance,reducing anxiety and depression levels,and improving coping styles and pelvic floor functional status.

THE EXISTENCE AND UNIQUENESS OF SOLUTION FOR A CLASS OF STOCHASTIC FUNCTIONAL EQUAFIONS ON S.P.SPACE

This paper is concerned with the existence and uniqueness of solution for a class of stochastic functional equation: X =φ(X), where φ: B → B and B is a Banach space consisted of all left-continuous, (■_t)-adapted processes. Also, the main result is applied to some S.D.E (or S.I.E.). And the authors adopted some of the results in current research in the models of stochastic control recently. This paper proves the ekistence and uniquence and uniqueness of solution for stochastic functional equation. A series of corollaries are deduced from the special examples of the theorems in this paper.

The Most Probable Mechanism Function and Kinetic Parameters of Gibbsite Dissolution in NaOH

Determination of probable mechanism function and kinetic parameters is important to hydrometallurgical kinetics.In this work,the most probable mechanism function and kinetic parameters of gibbsite dissolution in NaOH solution are studied.The sample,the mixture of synthetic gibbsite and sodium hydroxide solution,was scanned in high-pressure differential scanning calorimetry(DSC) equipment with the heating rate of 10 K·min-1. Integral equation and differential equation of non-isothermal kinetics were solved to fit the data related to DSC curve.According to the calculation results,the most probable mechanism function for pure synthetic gibbsite dissolution in sodium hydroxide solution is presented based on the optimum procedure in the database of the mechanism function.The apparent activation energy obtained is(75±1) kJ·mol-1,the frequency factor is 10 8±1mol·s-1,and the reaction is a second order reaction.

Neural differentiation of human Wharton＇s jelly-derived mesenchymal stem cells improves the recovery of neurological function after transplantation in ischemic stroke rats

Human Wharton＇s jelly-derived mesenchymal stem cells（h WJ-MSCs）have excellent proliferative ability,differentiation ability,low immunogenicity,and can be easily obtained.However,there are few studies on their application in the treatment of ischemic stroke,therefore their therapeutic effect requires further verification.In this study,h WJ-MSCs were transplanted into an ischemic stroke rat model via the tail vein 48 hours after transient middle cerebral artery occlusion.After 4 weeks,neurological functions of the rats implanted with h WJ-MSCs were significantly recovered.Furthermore,many h WJ-MSCs homed to the ischemic frontal cortex whereby they differentiated into neuron-like cells at this region.These results confirm that h WJ-MSCs transplanted into the ischemic stroke rat can differentiate into neuron-like cells to improve rat neurological function and behavior.

Buckling analysis of functionally graded plates partially resting on elastic foundation using the differential quadrature element method

We extend the differential quadrature element method (DQEM) to the buckling analysis of uniformly in-plane loaded functionally graded (FG) plates fully or partially resting on the Pasternak model of elastic support. Material properties of the FG plate are graded in the thickness direction and assumed to obey a power law distribution of the volume fraction of the constituents. To set up the global eigenvalue equation, the plate is divided into sub-domains or elements and the generalized differential quadrature procedure is applied to discretize the governing, boundary and compatibility equations. By assembling discrete equations at all nodal points, the weighting coefficient and force matrices are derived. To validate the accuracy of this method, the results are compared with those of the exact solution and the finite element method. At the end, the effects of different variables and local elastic support arrangements on the buckling load factor are investigated.

THE EXISTENCE OF PERIODIC SOLUTIONS FOR A CLASS OF FUNCTIONAL DIFFERENTIAL EQUATIONS AND THEIR APPLICATION

In this paper. four sufficiency theorems of existence of periodic solutions for aclass of retarded functional differential equations are given. The result of thesetheorems is better than the well-known Yoshizawa’s periodic solution theorem. Anexample of application is given at the end.

Three-dimensional magneto-thermo-elastic analysis of functionally graded cylindrical shell

The present paper presents the three-dimensional magneto-thermo-elastic analysis of the functionally graded cylindrical shell immersed in applied thermal and magnetic fields under non-uniform internal pressure. The inhomogeneity of the shell is assumed to vary along the radial direction according to a power law function, whereas Poisson＇s ratio is supposed to be constant through the thickness. The existing equations in terms of the displacement components, temperature, and magnetic parameters are derived, and then the effective differential quadrature method （DQM） is used to acquire the analytical solution. Based on the DQM, the governing heat differential equations and edge boundary conditions are transformed into algebraic equations, and discretized in the series form. The effects of the gradient index and rapid temperature on the displacement, stress components, temperature, and induced magnetic field are graphically illustrated. The fast convergence of the method is demonstrated and compared with the results obtained by the finite element method （FEM）.

Generalized thermoelastic functionally graded spherically isotropic solid containing a spherical cavity under thermal shock

This paper is concerned with the determination of thermoelastic displacement, stress and temperature in a functionally graded spherically isotropic infinite elastic medium having a spherical cavity, in the context of the linear theory of generalized thermoelasticity with two relaxation time parameters （Green and Lindsay theory）. The surface of cavity is stress-free and is subjected to a time-dependent thermal shock. The basic equations have been written in the form of a vector-matrix differential equation in the Laplace transform domain, which is then solved by an eigenvalue approach. Numerical inversion of the transforms is carried out using the Bellman method. Displacement, stress and temperature are computed and presented graphically. It is found that variation in the thermo-physical properties of a material strongly influences the response to loading. A comparative study with a corresponding homogeneous material is also made.

Effect of continuous nursing combined with respiratory exercise nursing on pulmonary function of postoperative patients with lung cancer

BACKGROUND Lung cancer is a malignant tumor with high morbidity and mortality among cancers.Surgery is currently one of the primary methods of treating lung cancer.Although it can slow down the progression of the disease by removing the lesion,this invasive surgery inevitably damages the integrity of the patient’s chest.Moreover,the patient’s pulmonary function may have a low compensatory capacity after surgery,causing various respiratory diseases such as atelectasis,respiratory function decline,and even serious cardiovascular disease.All of these have great negative impacts on the surgical effect and the prognosis of patients.With the continuous exploration and development of nursing,continuous nursing and respiratory exercise nursing have been gradually applied in the nursing of patients after lung cancer surgery,and have achieved good nursing results.AIM To investigate the effect of continuous nursing combined with respiratory exercise nursing on the pulmonary function of postoperative patients with lung cancer.METHODS A total of 80 patients with lung cancer who underwent surgery in our hospital from January 2021 to December 2021 were selected as the study subjects.All subjects were randomly divided into the control group(n=40 cases)and the experimental group(n=40 cases).Patients with lung cancer in the control group were given conventional nursing after surgery,while the experimental group was given continuous nursing combined with respiratory exercise nursing based on conventional nursing.The recovery of pulmonary function and respiratory symptoms was observed before and after 3 mo of intervention in both groups.The pulmonary function parameters,blood gas analysis,MD Anderson Symptom Inventory-lung cancer module(MDASI-LC)scores,incidence of pulmonary complications,and Morisky compliance scores were compared between the two groups before and after 3 mo of intervention.RESULTS There was no significant difference in pulmonary function and blood gas analysis between the two groups before intervention(P>0.05).3 mo after the intervention,the pulmonary function parameters in the experimental group(SpO2,VC,MVV,FEV1,FEV1%pred,and FEV1/FVC)were higher than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in blood gas analysis between the two groups before intervention(P>0.05).PaO2 in the experimental group was significantly higher than that in the control group,and PaCO_(2) was significantly lower than that in the control group 3 mo after the intervention.The difference had statistical significance(P<0.05).3 mo after the intervention,the MDASI score of respiratory symptoms in the experimental group was significantly lower than that in the control group(P<0.05),and the incidence of pulmonary complications was lower than that in the control group(P<0.05).In addition,the treatment compliance and nursing satisfaction of patients in the experimental group were higher than those in the control group,and the differences were statistically significant(P<0.05).CONCLUSION Continuous nursing combined with respiratory exercise nursing can significantly accelerate the recovery of respiratory function in postoperative lung cancer patients,reduce the incidence of postoperative complications of lung cancer as well as improve the treatment compliance of patients.

A continuous differentiable wavelet threshold function for speech enhancement

Enhanced speech based on the traditional wavelet threshold function had auditory oscillation distortion and the low signal-to-noise ratio (SNR). In order to solve these problems, a new continuous differentiable threshold function for speech enhancement was presented. Firstly, the function adopted narrow threshold areas, preserved the smaller signal speech, and improved the speech quality; secondly, based on the properties of the continuous differentiable and non-fixed deviation, each area function was attained gradually by using the method of mathematical derivation. It ensured that enhanced speech was continuous and smooth; it removed the auditory oscillation distortion; finally, combined with the Bark wavelet packets, it further improved human auditory perception. Experimental results show that the segmental SNR and PESQ (perceptual evaluation of speech quality) of the enhanced speech using this method increase effectively, compared with the existing speech enhancement algorithms based on wavelet threshold.

Dynamic Characteristics of Functionally Graded Timoshenko Beams by Improved Differential Quadrature Method

This study proposes an effective method to enhance the accuracy of the Differential Quadrature Method(DQM)for calculating the dynamic characteristics of functionally graded beams by improving the form of discrete node distribution.Firstly,based on the first-order shear deformation theory,the governing equation of free vibration of a functionally graded beam is transformed into the eigenvalue problem of ordinary differential equations with respect to beam axial displacement,transverse displacement,and cross-sectional rotation angle by considering the effects of shear deformation and rotational inertia of the beam cross-section.Then,ignoring the shear deformation of the beam section and only considering the effect of the rotational inertia of the section,the governing equation of the beam is transformed into the eigenvalue problem of ordinary differential equations with respect to beam transverse displacement.Based on the differential quadrature method theory,the eigenvalue problem of ordinary differential equations is transformed into the eigenvalue problem of standard generalized algebraic equations.Finally,the first several natural frequencies of the beam can be calculated.The feasibility and accuracy of the improved DQM are verified using the finite element method(FEM)and combined with the results of relevant literature.

Asymptotic Normality Distribution of Simulated Minimum Hellinger Distance Estimators for Continuous Models

Certain distributions do not have a closed-form density, but it is simple to draw samples from them. For such distributions, simulated minimum Hellinger distance (SMHD) estimation appears to be useful. Since the method is distance-based, it happens to be naturally robust. This paper is a follow-up to a previous paper where the SMHD estimators were only shown to be consistent;this paper establishes their asymptotic normality. For any parametric family of distributions for which all positive integer moments exist, asymptotic properties for the SMHD method indicate that the variance of the SMHD estimators attains the lower bound for simulation-based estimators, which is based on the inverse of the Fisher information matrix, adjusted by a constant that reflects the loss of efficiency due to simulations. All these features suggest that the SMHD method is applicable in many fields such as finance or actuarial science where we often encounter distributions without closed-form density.

A Denoising Algorithm for Noisy Chaotic Signals Based on the Higher Order Threshold Function in Wavelet-Packet

Aiming at the shortage of conventional threshold function in wavelet noise reduction of chaotic signals,we propose a wavelet-packet noise reduction method of chaotic signals based on a new higher order threshold function.The method retains the useful high-frequency information,and the threshold function is continuous and derivable,therefore it is more consistent with the characteristics of the continuous signal.Contrast simulation experiment shows that the effect of noise reduction and the precision of noise reduction of chaotic signals both are improved.

A numerical method based on boundary integral equations and radial basis functions for plane anisotropic thermoelastostatic equations with general variable coefficients

A boundary integral method with radial basis function approximation is proposed for numerically solving an important class of boundary value problems governed by a system of thermoelastostatic equations with variable coe?cients. The equations describe the thermoelastic behaviors of nonhomogeneous anisotropic materials with properties that vary smoothly from point to point in space. No restriction is imposed on the spatial variations of the thermoelastic coe?cients as long as all the requirements of the laws of physics are satis?ed. To check the validity and accuracy of the proposed numerical method, some speci?c test problems with known solutions are solved.