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A Brief Introduction of Stream of Consciousness as a Writing Technique
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作者 张利平 《内蒙古师范大学学报(哲学社会科学版)》 1999年第S3期43-47,52,共6页
As a writing technique, stream of consciousness has exerted a tremendous influence upon literature. In a stream-of-consciousness novel or short story, the authors usually use the following techniques to portray the &q... As a writing technique, stream of consciousness has exerted a tremendous influence upon literature. In a stream-of-consciousness novel or short story, the authors usually use the following techniques to portray the "stream of consciousness" of the character(s): interior monologue; free association; inversion of time and space. When the structure of thinking is considered, the portrayal of the stream of consciousness of the character(s) may fall into two types: the portrayal of individual conscious- ness and that of group consciousness. 展开更多
关键词 sTREAM of consciousness INTERIOR MONOLOGUE free association INVERsION of time and space individual consciousness group consciousness
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Group Psychological Intervention for Children with Hyperactivity Disorder
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作者 Ying Xu 《International Journal of Mental Health Promotion》 2023年第1期81-97,共17页
ADHD is a broad psychiatric disorder that affects children of normal or near-normal intelligence.It is character-ized by inattention,hyperactivity,and age-inappropriate impulsivity,and it is often accompanied by learn... ADHD is a broad psychiatric disorder that affects children of normal or near-normal intelligence.It is character-ized by inattention,hyperactivity,and age-inappropriate impulsivity,and it is often accompanied by learning dif-ficulties,behavioral,emotional,and interpersonal problems.On the other hand,hyperactive tendencies in children with ADHD exhibit ADHD-like behaviors such as lack of self-control,inattention,hyperactivity,and emotional impulsivity.However,because their symptoms are less severe,they do not meet the diagnostic criteria for ADHD but are ADHD or at risk of developing ADHD.The purpose of this study is to alleviate and reduce children’s hyperactivity symptoms by investigating the current situation of the children studied,and systemati-cally intervening and educating children with ADHD through psychological group intervention.Research data shows that ADHD is most commonly diagnosed in school-age children,and in 70%–80%of children with ADHD,symptoms persist into adolescence and 30%into adulthood.Through the use of group psychological intervention in the experiment,the prevalence rate of children with hyperactivity disorder tendency has been effectively reduced.This shows that group psychological intervention training has a significant effect on improving hyper-activity symptoms in children with ADHD tendency. 展开更多
关键词 Attention deficit hyperactivity disorder children’s group psychological intervention
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谷胱甘肽S转移酶P1和X线修复交错互补基因1基因多态性与前列腺癌化疗敏感性及预后关系研究
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作者 薛松 张祥 +2 位作者 潘鑫 易晓明 商学军 《中华男科学杂志》 CAS CSCD 2024年第9期803-808,共6页
目的:探究前列腺癌患者谷胱甘肽S转移酶P1(GSTP1)和X线修复交错互补基因1(XRCC1)基因多态性与化疗敏感性及预后的关系。方法:选取2018年5月至2021年5月行雄激素剥夺治疗+双药化疗的前列腺癌患者103例,收集患者临床资料,采用PCR-PFLP方... 目的:探究前列腺癌患者谷胱甘肽S转移酶P1(GSTP1)和X线修复交错互补基因1(XRCC1)基因多态性与化疗敏感性及预后的关系。方法:选取2018年5月至2021年5月行雄激素剥夺治疗+双药化疗的前列腺癌患者103例,收集患者临床资料,采用PCR-PFLP方法对患者行基因分型,并分析其GSTP1-rs1695位点和XRCC1-rs25487位点的多态性,分析其与化疗敏感性的关系,并探究GSTP1和XRCC1基因多态性与患者3年生存率的相关性。结果:103例前列腺癌化疗患者GSTP1-rs1695位点和XRCC1-rs25487位点分布均符合Hardy-Weinberg平衡(χ2=9.794,P>0.05)。GSTP1-rs1695位点中AA基因型占比为65.05%(67/103),AG基因型占比为23.30%(24/103),GG基因型占比为11.65%(12/103);XRCC1-rs25487位点中AA基因型占比为29.13%(30/103),AG基因型占比为50.49%(52/103),GG基因型占比为20.39%(21/103)。GSTP1-rs1695 AA型化疗敏感性为35.82%,低于AG/GG型58.33%(P<0.05)。XRCC1-rs25487 AA型化疗敏感性为40.00%,AG/GG型45.21%,两者差异无统计学意义(P>0.05)。GSTP1-rs1695、XRCC1-rs25487不同表型患者3年无进展生存率之间无明显差异(P>0.05)。GSTP1-rs1695 AA型3年总生存率低于AG/GG型;XRCC1-rs25487 AA型低于AG/GG型(P<0.05)。多因素COX回归分析结果显示,GSTP1-rs1695 AA型、XRCC1-rs25487 AA型均为前列腺癌患者化疗后3年总生存期的独立影响因素。结论:GSTP1-rs1695、XRCC1-rs25487基因多态性对前列腺癌患者化疗敏感性和预后均有一定影响,GSTP1-rs1695和XRCC1-rs25487 A等位基因突变均可导致更短的3年生存率,G等位基因突变可带来更好的化疗敏感性和生存期。 展开更多
关键词 前列腺癌 谷胱甘肽s转移酶P1 X线修复交错互补基因1 基因多态性 化疗敏感性
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Photo-activated microtubule targeting drugs: Advancing therapies for colorectal cancer
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作者 Naresh Singh Samantha Sharma 《World Journal of Gastroenterology》 SCIE CAS 2024年第26期3257-3260,共4页
Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies... Over the years immunotherapy has demonstrably improved the field of cancer treatment.However,achieving long-term survival for colorectal cancer(CRC)patients remains a significant unmet need.Combination immunotherapies incor-porating targeted drugs like MEK or multi-kinase inhibitors have offered some palliative benefit.Nevertheless,substantial gaps remain in the current therapeutic armamentarium for CRC.In recent years,there has been a surge of interest in exploring novel treatment strategies,including the application of light-activated drugs in conjunction with optical devices.This approach holds promise for achie-ving localized and targeted delivery of cytotoxic agents,such as microtubule-targeting drugs,directly to cancerous cells within the colon. 展开更多
关键词 Colorectal cancer Therapy MICROTUBULE Photo pharmacology Immuno-therapies©The Author(s)2024.Published by Baishideng Publishing group Inc.All rights reserved.
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Link between mutations in ACVRL1 and PLA2G4A genes and chronic intestinal ulcers:A case report and review of literature
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作者 Yong-Jing Tang Jian Zhang +7 位作者 Jie Wang Ren-Dong Tian Wei-Wei Zhong Ben-Sheng Yao Bing-Yu Hou Ying-Hua Chen Wei He Yi-Huai He 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第3期932-943,共12页
BACKGROUND Genetic factors of chronic intestinal ulcers are increasingly garnering attention.We present a case of chronic intestinal ulcers and bleeding associated with mu-tations of the activin A receptor type II-lik... BACKGROUND Genetic factors of chronic intestinal ulcers are increasingly garnering attention.We present a case of chronic intestinal ulcers and bleeding associated with mu-tations of the activin A receptor type II-like 1(ACVRL1)and phospholipase A2 group IVA(PLA2G4A)genes and review the available relevant literature.CASE SUMMARY A 20-year-old man was admitted to our center with a 6-year history of recurrent abdominal pain,diarrhea,and dark stools.At the onset 6 years ago,the patient had received treatment at a local hospital for abdominal pain persisting for 7 d,under the diagnosis of diffuse peritonitis,acute gangrenous appendicitis with perforation,adhesive intestinal obstruction,and pelvic abscess.The surgical treat-ment included exploratory laparotomy,appendectomy,intestinal adhesiolysis,and pelvic abscess removal.The patient’s condition improved and he was dis-charged.However,the recurrent episodes of abdominal pain and passage of black stools started again one year after discharge.On the basis of these features and results of subsequent colonoscopy,the clinical diagnosis was established as in-flammatory bowel disease(IBD).Accordingly,aminosalicylic acid,immunotherapy,and related symptomatic treatment were administered,but the symptoms of the patient did not improve significantly.Further investigations revealed mutations in the ACVRL1 and PLA2G4A genes.ACVRL1 and PLA2G4A are involved in angiogenesis and coagulation,respectively.This suggests that the chronic intestinal ulcers and bleeding in this case may be linked to mutations in the ACVRL1 and PLA2G4A genes.Oral Kangfuxin liquid was administered to promote healing of the intestinal mucosa and effectively manage clinical symptoms.CONCLUSION Mutations in the ACVRL1 and PLA2G4A genes may be one of the causes of chronic intestinal ulcers and bleeding in IBD.Orally administered Kangfuxin liquid may have therapeutic potential. 展开更多
关键词 Intestinal ulcers Crohn’s disease Ulcerative colitis Activin A receptor type II-like 1 Phospholipase A2 group 4A Case report
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Everything Is Timelessly Connected: Metaphysics, Physics, Consciousness, Spacetime Travel, DNA, and the Dry Bones Prophesy (Ezekiel Ch. 37)
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作者 Yosef Joseph Segman 《Natural Science》 CAS 2022年第7期265-288,共24页
This paper provides a perception that all things are connected. Starting with the perception of Metaphysics and how matter exists out of total void, complementary matter, or dark matter, the incompleteness of Einstein... This paper provides a perception that all things are connected. Starting with the perception of Metaphysics and how matter exists out of total void, complementary matter, or dark matter, the incompleteness of Einstein relativistic theory. Multi spacetime universes and the jump drive for jumping within and between spacetime universes. Warp drive for space travel. DNA as sequence of momentary frequencies and how it related to Ezekiel’s dry bones prophecy. The outcome of neural patterns as cords of consciousness, consciousness as the collection of all cords of consciousness and the lack of uniqueness of individual consciousness. Finally, all things are cords of consciousness. 展开更多
关键词 VOID COMPLEMENTARY Void Complementary MATTER Complementary Matter METAPHYsICs consciousness Neural Patterns Time Timeless synchronization Order Disorder Universe group Representation Jump Drive Warp Drive Frequency Phase Fourier Transform schrödinger Representation Gabor Transform DNA Hologram Virtual<sup>2sup>
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Comprehensive effects of traditional Chinese medicine treatment on heart failure and changes in B-type natriuretic peptide levels: A meta-analysis
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作者 Li-Li Xia Shu-Yun Yang +2 位作者 Jun-Yao Xu Han-Qing Chen Zhu-Yuan Fang 《World Journal of Clinical Cases》 SCIE 2024年第4期766-776,共11页
BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,... BACKGROUND Heart failure(HF),a common cardiovascular condition,is characterized by significant morbidity and mortality.While traditional Chinese medicine(TCM)is often used as a complementary approach in HF management,systematic evalua-tions of its impact on clinical outcomes,TCM syndrome scores,and B-type natriuretic peptide(BNP)levels are lacking.This study fills this gap through a comprehensive analysis of randomized controlled trials(RCTs)focusing on TCM for HF treatment.It encompasses an assessment of methodological quality,a meta-analysis,and an evaluation of evidence quality based on established standards.The results offer crucial insights into the potential advantages and constraints of TCM in HF management.RCTs on TCM for HF treatment published since the establishment of the database were searched in four Chinese and English databases,including China National Knowledge Infrastructure,Wanfang,VIP Information Chinese Science and Technology Journal,and PubMed.Methodological quality was assessed for the included studies with the Cochrane risk-of-bias assessment tool,and the meta-analysis and publication bias assessment was performed with the RevMan5.3 software.Finally,the quality of evidence was rated according to the GRADE criteria.RESULTS A total of 1098 RCTs were initially retrieved.After screening,16 RCTs were finally included in our study,which were published between 2020 and 2023.These RCTs involved 1660 HF patients,including 832 in the TCM group[TCM combined with conventional Western medicine(CMW)treatment]and 828 in the CWM group(CWM treatment).The course of treatments varied from 1 wk to 3 months.TCM syndrome differentiation was analyzed in 11 of the included RCTs.In all included RCTs,outcome indicators included comprehensive clinical outcomes,TCM syndrome scores,and BNP levels.The meta-analysis results showed significant differences between the TCM and CWM groups in terms of comprehensive clinical outcomes[risk ratio=-0.54;95%confidence interval(CI)=-0.61,-0.47;P<0.00001],TCM syndrome scores[weighted mean difference(WMD)=-142.07;95%CI=-147.56,-136.57;P<0.00001],and BNP levels(WMD=-142.07;95%CI=-147.56,-136.57;P<0.00001).According to the GRADE criteria,RCTs where"TCM improves clinical comprehensive outcomes"were rated as low-quality evidence,and RCTs where"TCM reduces TCM syndrome scores"or"TCM decreases BNP levels"were rated as medium-quality evidence.CONCLUSION TCM combined with CWM treatment effectively improves comprehensive clinical outcomes and diminishes TCM syndrome scores and BNP levels in HF patients.Given the low and medium quality of the included RCTs,the application of these results should be cautious. 展开更多
关键词 Traditional Chinese medicine Heart failure Comprehensive clinical outcomes Traditional Chinese medicine syndrome score B-type natriuretic peptide level Meta-analysis©The Author(s)2024.Published by Baishideng Publishing group Inc.
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Research of Social Problems under Global Vision, Local Consciousness and People's Standard --Take analysis of the design intention of individual account as example
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作者 Wang Min Min Zhu Yi 《International English Education Research》 2015年第5期78-80,共3页
In the study of social problems, it is important to realize the organic combination of global view, local people standard,, which plays an important role in handing and understanding specific social problems undoubted... In the study of social problems, it is important to realize the organic combination of global view, local people standard,, which plays an important role in handing and understanding specific social problems undoubtedly. This article takes our country's public pension personal account as example ,analyzing how to realize the combination of all three in the whole research process of the individual account. 展开更多
关键词 global view native consciousness people's standard individual account
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CHINA'S SELF-CONFIDENCE AND CONSCIOUSNESS IN GLOBAL GOVERNANCE
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作者 WANG YIWEI 《Contemporary World》 2017年第1期30-33,共4页
'China should make greater contributions to mankind.'Such contributions are now to be found more and more on the level of global governance.As General Secretary Xi Jinping observed in his New Year Address of 2... 'China should make greater contributions to mankind.'Such contributions are now to be found more and more on the level of global governance.As General Secretary Xi Jinping observed in his New Year Address of 2016,'the world is too big,and challenges are too many,to go without the voice from China being heard,without solution ideas from China being shared,without the involvement of China being needed'. 展开更多
关键词 CHINA’s sELF-CONFIDENCE AND consciousness IN GLOBAL GOVERNANCE CPC BUILDER MORE
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Kezia's Consciousness and Unconsciousness in The Doll's House
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作者 徐舒仪 《海外英语》 2016年第10期145-146,共2页
The Doll's House is one of the most famous representatives of Katherine Mansfield. She makes use of simple words to tell the story, but she vividly depicts the reality that the discrimination to the poor still exi... The Doll's House is one of the most famous representatives of Katherine Mansfield. She makes use of simple words to tell the story, but she vividly depicts the reality that the discrimination to the poor still exists. This phenomenon influences not only the world of adult but also the world of children. Kezia is the protagonist in The Doll's House. She is different from other members in her family. Although she is influenced by the canons in the adult world, she is not totally assimilated by these invisible principles. Kezia's consciousness and unconsciousness play important roles in indicating Katherine Mansfield's attitude towards the discrimination which she doesn't express directly. By analyzing Kezia's these two aspects in her mind, people's attention to the poor can be called and people's kindness and sympathy to them can be aroused. 展开更多
关键词 Katherine MANsFIELD The Doll’s HOUsE Kezia consciousness UNconsciousness
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“共享、联动、创生”:U-G-S框架下的集团化办学创新探索——以上海师范大学嘉定基础教育集团为例
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作者 吴宝英 《现代基础教育研究》 2024年第3期38-42,共5页
促进优质均衡发展,推进学区化集团化办学,是上海深化基础教育领域综合改革、积极回应人民群众接受高质量教育需求的重要举措。以“共享、联动、创生”为主旨,上海师范大学嘉定基础教育集团进行了U-G-S框架背景下的新型集团化办学创新探... 促进优质均衡发展,推进学区化集团化办学,是上海深化基础教育领域综合改革、积极回应人民群众接受高质量教育需求的重要举措。以“共享、联动、创生”为主旨,上海师范大学嘉定基础教育集团进行了U-G-S框架背景下的新型集团化办学创新探索,逐步积累了U-G-S框架下的集团愿景共享、重大项目联动、龙头课题创生等方面的经验,并取得了初步成效。 展开更多
关键词 集团化办学 U-G-s框架 创新探索
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数论中的Wilson定理通过群论中的Cauchy定理的证明
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作者 张海诚 《高等数学研究》 2024年第5期93-93,F0003,共2页
本文利用近世代数课程中有限群的Cauchy定理证明数论课程里的Wilson定理.
关键词 数论 WILsON定理 群论 CAUCHY定理
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Space and Human Consciousness: The Great Whisper
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作者 Abdullah A. Alabdulgader 《Natural Science》 2021年第7期235-253,共19页
Human Consciousness is one of most elusive issues in the scientific history. Its nature created major historical debate started thousands of years ago and still ongoing. Despite the explosive developments in the last ... Human Consciousness is one of most elusive issues in the scientific history. Its nature created major historical debate started thousands of years ago and still ongoing. Despite the explosive developments in the last century to explore its nature, the knowledge about it is still deficient. The important advances in the twentieth and 21st centuries in understanding cerebral cortex dynamics fortified by the dominant materialistic approach of the era dictated its impact on consciousness science, which is perceived as sole human brain function. This original review is a call for holistic perception of human consciousness incorporating the ancient wisdom of the human civilizations with the massive current era advances in different disciplines of applied sciences. The description of René Descartes in the 17th century of the Cartesian dualism is timely to revisit with new holistic perspective, in view of the major advances of our understanding of heart brain communications, astrophysical resonances with human heart ascending afferents to central nervous system, and signaling between humans and the space. Universal vibrations, frequencies and resonances as perceived by Nikola Tesla constitute the core of our new conceptual and experimental perspective on human consciousness. Neural and psychological correlates of human consciousness which dominate the consciousness research nowadays should undergo revolutionary conceptual understanding to perceive consciousness as a massive universal event expanding from human genes to galaxies. In the next discussion, we are going to navigate in the nature and fate of human consciousness with new innovative universal perspective based on heart rate variability of human heart and its cosmic resonances as represented by Schumann Resonances, Solar Wind Indices and Galactic Cosmic Rays. The interpretation of our existential secrets and biology without the space around us is a major gap in our scientific perception of life. The delicate orchestration between human heart and the space frequencies create the great whisper which in our perspective, encodes the secrets of human consciousness. 展开更多
关键词 sPACE consciousness Whisper Heart Rate Variability Frequencies (HRV) Heart Based Resonant Frequencies Theory (HBRF) solar Geomagnetic Activity (s-GMA)
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On s*-Completions of Maximal Subgroups of Finite Groups 被引量:1
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作者 高辉 高胜哲 尹丽 《Chinese Quarterly Journal of Mathematics》 2015年第3期381-388,共8页
Given a maximal subgroup M of a group G, a θ*-completion C of M is called an s*-completion if either C = G or there exists a subgroup D of G which is not a θ*-completion of M such that D contains C as a maximal subg... Given a maximal subgroup M of a group G, a θ*-completion C of M is called an s*-completion if either C = G or there exists a subgroup D of G which is not a θ*-completion of M such that D contains C as a maximal subgroup. In this paper, we obtain several results on s*-completions which imply G to be solvable or supersolvable. 展开更多
关键词 MAXIMAL sUBgroups θ*-completions s*-completions sOLVABLE groups super-solvable groups
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ON CRITICAL CASES OF SOBOLEV'S INEQUALITIES FOR HEISENBERG GROUPS 被引量:1
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作者 杨乔华 《Acta Mathematica Scientia》 SCIE CSCD 2012年第4期1584-1592,共9页
We prove some Trudinger-type inequalities and Brezis-Gallouet-Wainger inequality on the Heisenberg group, extending to this context the Euclidean results by T. Ozawa.
关键词 sobolev's inequality Brezis-Gallouet-Wainger inequality Heisenberg group
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Symmetry Groups and New Exact Solutions to (2+1)-Dimensional Variable Coefficient Canonical Generalized KP Equation 被引量:7
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作者 ZHANG Li-Hua LIU Xi-Qiang BAI Cheng-Lin 《Communications in Theoretical Physics》 SCIE CAS CSCD 2007年第3X期405-410,共6页
In this paper, the modified CK's direct method to find symmetry groups of nonlinear partial differential equation is extended to (2+1)-dimensional variable coeffficient canonical generalized KP (VCCGKP) equation... In this paper, the modified CK's direct method to find symmetry groups of nonlinear partial differential equation is extended to (2+1)-dimensional variable coeffficient canonical generalized KP (VCCGKP) equation. As a result, symmetry groups, Lie point symmetry group and Lie symmetry for the VCCGKP equation are obtained. In fact, the Lie point symmetry group coincides with that obtained by the standard Lie group approach. Applying the given Lie symmetry, we obtain five types of similarity reductions and a lot of new exact solutions, including hyperbolic function solutions, triangular periodic solutions, Jacobi elliptic function solutions and rational solutions, for the VCCGKP equation. 展开更多
关键词 (2+1)-dimensional variable coefficient canonical generalized KP (VCCGKP) equation modified CK's'direct method symmetry groups Lie symmetry similarity reductions new exact solutions
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Synthesis and mesomorphic properties of fluorinated Schiff's base liquid crystals containing vinyl end groups 被引量:1
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作者 Qiang Wei Siquan Zhu +4 位作者 Lin Shi Lipei Zhang Xiaotao Yuan Hui Cao Huai Yang 《Journal of University of Science and Technology Beijing》 CSCD 2007年第4期373-377,共5页
Three kinds of fluorinated Schiff's base esters, 4-allyloxy-2-X-6-X-benzoic acid 4-[(2, 3, 4-trifluorophenylimino)methyl]phenyl ester, where X=H or F, were synthesized and characterized. Their chemical structures w... Three kinds of fluorinated Schiff's base esters, 4-allyloxy-2-X-6-X-benzoic acid 4-[(2, 3, 4-trifluorophenylimino)methyl]phenyl ester, where X=H or F, were synthesized and characterized. Their chemical structures were identified by Fourier transform infrared spectroscopy (FTIR) and ^1H nuclear magnetic resonance (^1H NMR). Their mesomorphic properties were studied by polarized optical microscopy (POM) and differential scanning calorimetry (DSC). It was found that all the three compounds exhibited enantiotropic nematic phases only. And their cleating point temperature and thermal range of mesophase decreased with the number of fluorine atoms on the rigid core of the compounds; while their melting point temperature showed no distinct regularity. 展开更多
关键词 sYNTHEsIs schiff's base fluorinated liquid crystal vinyl end group
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Entanglement of E8E8 Exceptional Lie Symmetry Group Dark Energy, Einstein’s Maximal Total Energy and the Hartle-Hawking No Boundary Proposal as the Explanation for Dark Energy 被引量:7
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作者 Mohamed S. El Naschie 《World Journal of Condensed Matter Physics》 2014年第2期74-77,共4页
The present note is concerned with two connected and highly important fundamental questions of physics and cosmology, namely if E8E8 Lie symmetry group describes the universe and where cosmic dark energy comes from. F... The present note is concerned with two connected and highly important fundamental questions of physics and cosmology, namely if E8E8 Lie symmetry group describes the universe and where cosmic dark energy comes from. Furthermore, we reason following Wheeler, Hartle and Hawking that since the boundary of a boundary is an empty set which models the quantum wave of the cosmos, then it follows that dark energy is a fundamental physical phenomenon associated with the boundary of the holographic boundary. This leads directly to a clopen universe which is its own Penrose tiling-like multiverse with energy density in full agreement with COBE, WMAP and Type 1a supernova cosmic measurements. 展开更多
关键词 E8 Exceptional Lie symmetry group Dark Energy Einstein’s Relativity E-INFINITY Theory Wheeler BOUNDARY of a BOUNDARY Hartle-Hawking NO BOUNDARY PROPOsAL Penrose Tiling Multiverse
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Influence of group B streptococcus and vaginal cleanliness on the vaginal microbiome of pregnant women 被引量:1
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作者 Qi Liao Xiao-Fen Zhang +3 位作者 Xin Mi Feng Jin Hong-Min Sun Qing-Xuan Wang 《World Journal of Clinical Cases》 SCIE 2022年第34期12578-12586,共9页
BACKGROUND The vaginal microbiome plays a critical role in the health of pregnant women and their newborns.Group B Streptococcus(GBS)and vaginal cleanliness significantly affect the vaginal microecosystem and are clos... BACKGROUND The vaginal microbiome plays a critical role in the health of pregnant women and their newborns.Group B Streptococcus(GBS)and vaginal cleanliness significantly affect the vaginal microecosystem and are closely associated with vaginal diseases.AIM To explore the effects of GBS status and vaginal cleanliness on vaginal microecosystems.METHODS We collected 160 vaginal swabs from pregnant women and divided them into the following four groups based on GBS status and vaginal cleanliness:GBS-positive+vaginal cleanliness I–II degree,GBS-negative+vaginal cleanliness I–II degree,GBS-positive+vaginal cleanliness III–IV degree,and GBS-negative+vaginal cleanliness III–IV degree.Samples were subjected to 16S rRNA gene amplicon sequencing.RESULTS Alpha diversity analysis showed that the Shannon index did not significantly differ between the four groups.We identified significant variation in taxa abundance between the GBS-positive and GBS-negative groups and between the vaginal cleanliness I–II degree and III–IV degree groups.Principal coordinate analysis and non-metric multidimensional scaling analysis further confirmed the microbial diversity of the four groups.Moreover,the linear discriminant analysis demonstrated that Lactobacillus jensenii and Actinobacteria were strongly associated with GBS-positive status,and Lactobacillus iners,Lactobacillaceae,Lactobacillus,Lactobacillales,Bacilli and Firmicutes were closely correlated with GBS-negative status.CONCLUSION GBS status and vaginal cleanliness significantly affect vaginal microbiome differences in pregnant women.Our findings provide instructional information for clinical antibiotic treatment in pregnant women with different GBS statuses and vaginal cleanliness degrees. 展开更多
关键词 Vaginal microbiome Pregnant women 16s rRNA gene amplicon sequencing group B streptococcus Vaginal cleanliness
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Lie Symmetry Groups of(2+1)-Dimensional BKP Equation and Its New Solutions 被引量:1
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作者 MA Hong-Cai LOU Sen-Yue DENG Ai-Ping 《Communications in Theoretical Physics》 SCIE CAS CSCD 2008年第9期685-688,共4页
A modified direct method is developed to find finite symmetry groups of nonlinear mathematical physicssystems.Applying the modified direct method to the well-known (2+1)-dimensional BKP equation we get its symmetry.Fu... A modified direct method is developed to find finite symmetry groups of nonlinear mathematical physicssystems.Applying the modified direct method to the well-known (2+1)-dimensional BKP equation we get its symmetry.Furthermore,the exact solutions of (2+1)-dimensional BKP equation are obtained through symmetry analysis. 展开更多
关键词 (2+1)-dimensional BKP equation Lie symmetry group CK's direct method exact solution
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