Variations of OCT measurements corrected for the magnification effect according to axial length and refractive error in children

Purpose:The aim of this paper was to examine the distribution of macular,retinal nerve fiber layer(RNFL)thickness and optic disc parameters of myopic and hyperopic eyes in comparison withemmetropic control eyes and to investigate their variation according to axial length(AL)andspherical equivalent(SE)in healthy children.Methods:This study included 293 pairs of eyes of 293children(145 boys and 148 girks),ranging in age from 6 to 17 years,Subjects were dividedaccording to SE in control(emmetropia,99 children),myopia(100 children)and hyperopia(94children)groups and according to axial AL in 68 short(<22.00 mm,68),medium(from≥22.00 mmto 25.00 mm,189)and long eyes(>25.00 mm,36).Macular parameters,RNFL thickness and opticdisc morphology were assessed by the Cirrus^(TM) HD-OCT.AL was measured using the IOL-Mastersystem.Littmann's formula was used for calculating the corrected AL-related ocular magnification.Results Mean age(±SD)was 10.84±3.05 years;mean(±SD)SE was+0.14±0.51 D(range from8.75 to+8.25 D)and mean AL(±SD)was 23.12±1.49.Average RNFL thickness,averagemacular thickness and macular volume decreased as AL and myopia increased.No correlationsbetween AL/SE and optic disc parameters were found after correcting for magnification effect.Conclusions:AL and refractive error affect measurements of macular and RNFL thickness inhealthy children.To make a correct interpretation of ocT measurements,ocular magnificationeffect should be taken into account by clinicians or OCT manufacturers.

On constructing symmetrical reversible variable-length codes independent of the Huffman code

Reversible variable length codes (RVLCs) have received much attention due to their excellent error resilient capabilities. In this paper, a novel construction algorithm for symmetrical RVLC is proposed which is independent of the Huffman code. The proposed algorithm's codeword assignment is only based on symbol occurrence probability. It has many advantages over symmetrical construction algorithms available for easy realization and better code performance. In addition, the proposed algorithm simplifies the codeword selection mechanism dramatically.

Estimating the Baseline Error of Wide-Swath Altimeters Using Nadir Altimeters via Numerical Simulation

The baseline roll and length errors for wide-swath altimeters are major error sources in sea surface measurements that exhibit strong spatial characteristics in the cross-track direction.These errors can be identified and estimated in accordance with height differences at crossover points generated with nadir altimeters after excluding the interference from other error sources.Most of the wide-swath altimeter baseline estimation methods considered only the roll error in previous studies.A numerical simulation was conducted in this study using nadir altimeters to estimate the roll and length errors simultaneously to provide a selectable scheme for baseline error estimation and correction for future wide-swath altimeters.Results based on the parameters of the surface water and ocean topography mission and Sentinel-3A show that the correlation coefficient of the roll error between the estimated and simulated values is 0.89,while the correlation coefficient of the length error is 0.85.The sea surface height root mean square error(RMSE)can be reduced from 12.18 cm to 6.45 cm based on the two estimated results.The estimation effect can be increased by using multiple nadir altimeters to form an observation constellation.The numerical simulation of the five nadir altimeter constellation shows that the correlation coefficients of the roll and length errors would increase to 0.97,which reduces the sea surface height RMSE to 2.88 cm.In addition,the stability of this method is indicated in simulation experiments,which introduce different degrees of sea state errors.

On Error Analysis and Refinement of the Measurement of Plane-to-Plane Perpendicularity

The principle of planc-to-plane perpendicularity measuring with coordinate measuring machine （CMM） is described and the main factors that influence the measuring precision are analyzed. The minimum condition method is adopted to eliminate the fitting error of the datum plane. In order to diminish the length error of the object plane, the tactics of measuring some part of the plane and then scale to the whole plane is employed. With large quantity of measuring experiments on fiat plates, the most appropriate number of points in measuring a plane is determined to reduce the sampling error.

Error Modeling and Sensitivity Analysis of a Parallel Robot with SCARA(Selective Compliance Assembly Robot Arm) Motions

Parallel robots with SCARA（selective compliance assembly robot arm） motions are utilized widely in the field of high speed pick-and-place manipulation. Error modeling for these robots generally simplifies the parallelogram structures included by the robots as a link. As the established error model fails to reflect the error feature of the parallelogram structures, the effect of accuracy design and kinematic calibration based on the error model come to be undermined. An error modeling methodology is proposed to establish an error model of parallel robots with parallelogram structures. The error model can embody the geometric errors of all joints, including the joints of parallelogram structures. Thus it can contain more exhaustively the factors that reduce the accuracy of the robot. Based on the error model and some sensitivity indices defined in the sense of statistics, sensitivity analysis is carried out. Accordingly, some atlases are depicted to express each geometric error’s influence on the moving platform’s pose errors. From these atlases, the geometric errors that have greater impact on the accuracy of the moving platform are identified, and some sensitive areas where the pose errors of the moving platform are extremely sensitive to the geometric errors are also figured out. By taking into account the error factors which are generally neglected in all existing modeling methods, the proposed modeling method can thoroughly disclose the process of error transmission and enhance the efficacy of accuracy design and calibration.

Motor Imagery and Error Related Potential Induced Position Control of a Robotic Arm

The paper introduces an electroencephalography(EEG) driven online position control scheme for a robot arm by utilizing motor imagery to activate and error related potential(ErrP) to stop the movement of the individual links, following a fixed(pre-defined) order of link selection. The right(left)hand motor imagery is used to turn a link clockwise(counterclockwise) and foot imagery is used to move a link forward. The occurrence of ErrP here indicates that the link under motion crosses the visually fixed target position, which usually is a plane/line/point depending on the desired transition of the link across 3D planes/around 2D lines/along 2D lines respectively. The imagined task about individual link's movement is decoded by a classifier into three possible class labels: clockwise, counterclockwise and no movement in case of rotational movements and forward, backward and no movement in case of translational movements. One additional classifier is required to detect the occurrence of the ErrP signal, elicited due to visually inspired positional link error with reference to a geometrically selected target position. Wavelet coefficients and adaptive autoregressive parameters are extracted as features for motor imagery and ErrP signals respectively. Support vector machine classifiers are used to decode motor imagination and ErrP with high classification accuracy above 80%. The average time taken by the proposed scheme to decode and execute control intentions for the complete movement of three links of a robot is approximately33 seconds. The steady-state error and peak overshoot of the proposed controller are experimentally obtained as 1.1% and4.6% respectively.

Not Relying on the Newton Gravitational Constant Gives More Accurate Gravitational Predictions

The Newton gravitational constant is considered a cornerstone of modern gravity theory. Newton did not invent or use the gravity constant;it was invented in 1873, about the same time as it became standard to use the kilogram mass definition. We will claim that G is just a term needed to correct the incomplete kilogram definition so to be able to make gravity predictions. But there is another way;namely, to directly use a more complete mass definition, something that in recent years has been introduced as collision-time and a corresponding energy called collision-length. The collision-length is quantum gravitational energy. We will clearly demonstrate that by working with mass and energy based on these new concepts, rather than kilogram and the gravitational constant, one can significantly reduce the uncertainty in most gravity predictions.

Relationship between Refractive Error and Ocular Biometrics in Twin Children:the Guangzhou Twin Eye Study

Purpose:A cross-sectional study was conducted to explore the relationship between refractive error and ocular biometrics in children from the Guangzhou twin eye study.Methods:.Twin participants aged 7-15 years were selected from Guangzhou Twin Eye Study..Ocular examinations included visual acuity measurement, ocular motility evaluation, autorefraction under cycloplegia, and anterior segment, media, and fundus examination...Axial length(AL),..anterior cham ber depth(ACD), and corneal curvature radius were measured using partial coherence laser interferometry. A multivariate linear regression model was used for statistical analysis.Results:.Twin children from Guangzhou city showed a decreased spherical equivalent with age,.whereas both AL and ACD were increased and corneal curvature radius remained unchanged. When adjusted by age and gender, the data from77% of twins presenting with spherical equivalent changes indicated that these were caused by predictable variables.(R2=0.77, P<0.001). Primary factors affecting children's refraction included axial length(β=-0.97,P<0.001), ACD(β=0.33,P<0.001), and curvature radius(β=2.10,P<0.001). Girls had a higher tendency for myopic status than did boys(β=-0.26,P<0.001)..Age exerted no effect upon the changes in refraction(β=-0.01, P=0.25).Conclusion:.Refraction is correlated with ocular biometrics.Refractive status is largely determined by axial length as the major factor.

The Variables and Invariants in the Evolution of Logic Optical Lithography Process

Photolithography has been a major enabler for the continuous shrink of the semiconductor manufacturing design rules.Throughout the years of the development of the photolithography,many new technologies have been invented and successfully implemented,such as image projection lithography,chemically amplified photoresist,phase shifting mask,optical proximity modeling and correction,etc.From 0.25μm technology to the current 7 nm technology,the linewidth has been shrunk from 250 nm to about 20 nm,or 12.5 times.Although imaging resolution is proportional to the illumination wavelength,with the new technologies,the wavelength has only been shrunk from 248 nm to 134.7 nm(193 nm immersion in water),less than 2 times.Would it mean that the imaging performance has been continuously declining?Or we have yet fully utilized the potential of the photolithography technology?In this paper,we will present a study on the key parameters and process window performance of the image projection photolithography from 0.25μm node to the current 7 nm node.

ADAPTIVE FUZZY CONTROL FOR ROBOT ARM MANIPULATOR WITH 5-DOF

To control the robot and track the designed trajectory with uncertain disturbances in a specified precision range, an adaptive fuzzy control scheme for the robot arm manipulator is discussed. The controller output error method （COEM） is used to design the adaptive fuzzy controller. A few or all of the parameters of the controller are adjusted by using the gradient descent algorithm to minimize the output error. COEM is adopted in the adaptive control system for the robot arm manipulator with 5-DOF. Simulation results show the effectiveness of the method and the real time adjustment of the parameters.

ANALYSIS OF LEVER ARM EFFECTS IN GPS／IMU INTEGRATION SYSTEM

Disturbance specific force caused by the lever arm ef-fects in integration navigation system is investigated,Navigation errors eaused by the lever arm effects have been demonstrated under three flinght scenarios of the air-craft.Analytical under three flight scenarios of the ari-craft.Analytical results show that disturbance specific force resulted from lever arm effects may become one of the major error sources while an aircraft undertakes the maneuvers,and mavigation errors caused by the lever arm effects accumulate rapidly with time.Therefore,a com-pensation method must be taken into account to eliminate the disturbance specific force caused by the lever arm ef-fects in integration navigation system.

Axial length,vitreoretinal pathology,and anterior chamber depth can predict postoperative refractive outcomes in phacovitrectomy/silicone oil removal

AIM:To evaluate the postoperative refractive prediction error(PE)and determine the factors that af fect the refractive outcomes of combined pars plana vitrectomy(PPV)or silicone oil removal(SOR)with cataract surgery.METHODS:The study is a retrospective,case-series study.Totally 301 eyes of 301 patients undergoing combined PPV/SOR with cataract surgery were enrolled.Eligible individuals were separated into four groups according to their preoperative diagnoses:silicone oil-filled eyes after PPV(group 1),epiretinal membrane(group 2),macular hole(group 3),and primary retinal detachment(RD;group 4).The variables af fecting postoperative refractive outcomes were analyzed,including age,gender,preoperative best-corrected visual acuity(BCVA),axial length(AL),keratometry average,anterior chamber depth(ACD),intraocular tamponade,and vitreoretinal pathology.The outcome measurements include the mean refractive PE and the proportions of eyes with a PE within±0.50 diopter(D)and±1.00 D.RESULTS:For all patients,the mean PE was-0.04±1.17 D,and 50.17%of patients(eyes)had a PE within±0.50 D.There was a significant difference in refractive outcomes among the four groups(P=0.028),with RD(group 4)showing the least favorable refractive outcome.In multivariate regression analysis,only AL,vitreoretinal pathology,and ACD were strongly associated with PE(all P<0.01).Univariate analysis revealed that longer eyes(AL>26 mm)and a deeper ACD were correlated with hyperopic PE,and shorter eyes(AL<26 mm)and a shallower ACD were correlated with myopic PE.CONCLUSION:RD patients have the least favorable refractive outcome.AL,vitreoretinal pathology,and ACD are strongly associated with PE in the combined surgery.These three factors affect refractive outcomes and thus can be used to predict a better postoperative refractive outcome in clinical practice.

Medication Error and Interprofessional Communication-Related Factors Contributing to Hospitalisation in Community-Dwelling Older Adults in Australia

Background: Population ageing is a worldwide phenomenon. It is common for older adults to develop multiple age-related illnesses and the prevalence of multimorbidity increases substantially with age. Multimorbid adults are frequently treated with several concurrent medications and the regimen may be complex requiring multiple steps in the preparation of a medication prior to its administration. Polypharmacy is a concerning trend and older adults have a 100% risk of experiencing adverse drug events when taking ten or more medications concurrently. Discharge summaries communicating the number of medications, changes made to medication regimens during hospitalisations and the requirement for ongoing monitoring in the community are often incomplete. The aim of this study was to investigate contributing factors to medication-related hospitalisation, length of stay or readmission in older community-dwelling persons and examine the quality of discharge summaries. Methods: Descriptive and correlational analyses of demographic, clinical, admission, readmission, length of stay and medication variables were examined in Australia in 2016-2018. Discharge summaries were analysed for completeness, timeliness and interprofessional communication. Results: There were 295 participants, mean age 80 years, 55% were female, taking an average of 11 prescribed medications and with a mean Medication Regimen Complexity Index score of 34. Medication errors that were unrecognised at the time of hospitalisation were present in 19% of the sample. Factors associated with medication error were older age and a longer median length of stay. Fewer than 52% of these older patients had detailed discharge summaries. Conclusion: The prevalence of polypharmacy and medication regimen complexity at admission was high. A high proportion of older adults on medical units may have unrecognised medication errors impacting their admission. Medical discharge summaries are inadequately addressing this issue for patients returning to the care of their family physician.

Residual refractive errors in pseudophakic eyes and related factors:a population-based study

AIM: To determine residual refractive error after cataract surgery in pseudophakic eyes and its relationship with age, sex, and axial length(AL).METHODS: In this population-based cross-sectional study, the sampling was performed on individuals aged 60y and above in Tehran, Iran using a multi-stage stratified random cluster sampling method. Pseudophakic eyes with a best-corrected visual acuity of 20/32 or better were analyzed and their refractive results were reported.RESULTS: The mean spherical equivalent(SE) refraction was-0.34±0.97 diopters(D) and the mean absolute SE was 0.72±0.74 D with a median of 0.5 D. Moreover, 32.68%(n=546, 95%CI: 30.27%-35.08%), 53.67%(n=900, 95%CI: 51.23%-56.1%), 68.99%(n=1157, 95%CI: 66.96%-71.02%), and 79.73%(n=1337, 95%CI: 77.69%-81.76%) of the eyes had a residual SE within ±0.25, ±0.50, ±0.75, and ±1.00 D of emmetropia, respectively. According to the multiple logistic regression model, increasing age was associated with a statistically significant decrease in predictability for all cut points. Moreover, the predictability based on all cut points was significantly lower in individuals with an AL longer than 24.5 mm than in those with an AL between 22 to 24.5 mm.CONCLUSION: Based on the results, the accuracy of intraocular lens(IOL) power calculation is lower for those who underwent cataract surgery during the last 5y in Tehran, Iran. Among the most important influential factors, the choice of IOL or it's power disproportionate to eye conditions and age can be mentioned.

水平偏心摆波能装置运动获能特性研究

以水平偏心摆波能装置为对象,通过物理模型试验和数值模拟,对装置在单自由度和多自由度下的运动和获能规律进行研究。不同波周期下,摆体出现小幅振荡、旋转和振荡旋转三种运动状态。研究表明,装置在单自由度下出现对获能不利的“锁停”现象,而多自由度的获能相对较好,平均功率随波浪周期出现两次峰值。第一次峰值对应波周期与能量输出(PTO)阻尼和摆臂长度正相关,峰值与PTO阻尼正相关;第二次峰值及对应波周期与外浮体轴比正相关。

考虑弹性变形的机械臂末端位姿误差补偿技术研究

常规的机械臂末端位姿误差补偿技术主要采用求解位置参数实现位姿误差补偿,忽略了机械臂自身弹性变形对误差补偿的影响,导致补偿结果精度较低.因此,提出考虑弹性变形的机械臂末端位姿误差补偿技术研究.构建以四参数定义为基础的机械臂末端运动学建模,在此基础上,基于抗拉强度等参数分析机械臂连杆、关节以及末端三个部位的弹性变形误差量,建立机械臂原点坐标系对位姿参数进行辨识,综合弹性变形情况计算位姿误差补偿值.实验结果表明:所提技术应用后得出的误差补偿结果表现出的标定轨迹重复度较高,补偿结果精度较高,满足了机械臂的实际应用精度需求.

某电动汽车减速器微观修形分析

新能源电动汽车减速器取代了传统汽车变速器,可以实现汽车的前进、停止、倒退等功能。新能源电动汽车减速器的核心部件是齿轮,齿轮性能的好坏直接影响电动汽车减速器的工作性能。基于Romax软件对新能源电动汽车减速器的齿轮进行了微观分析,对一级齿轮副小齿轮进行了齿向修形和齿廓修形,以满足实际工作需要。

双臂工业机器人协作定位精度姿态误差校正

为提高机械臂在货物交接时对多种控制状态的适应能力,设计了一种双臂工业机器人协作定位精度姿态误差校正方法,以达到械臂运动参数校准的目的。建立了机械臂残余姿态误差数学模型,精确地对机械臂残余定位误差进行计算。研究结果表明:运动特性曲线呈现平滑分布的特点,加速度突变程度很小,表明该系统能够满足工况作业要求。姿态误差有效补偿能够更精确完成两臂协同定位,从而准确识别手臂基座标变换参数。本研究有助于提高双臂工业机器人协作动作效率,为后续的参数优化奠定一定的理论基础。

煤矿用钻孔机器人钻臂定位误差补偿研究

目前钻孔机器人位姿调节多采用手动遥控调节与人工复测结合,未实现全自动调节,开环控制精度低、自动化能力低、无法实现煤矿用探放水、防突和防冲钻孔机器人精确开孔定位与孔群全自动施工。通过分析钻孔机器人钻臂结构和动作,建立了钻臂运动学模型;通过对加工误差、机身变形、装配间隙等影响因素分析,发现采用回转减速器蜗轮蜗杆结构间隙会引起倾角和方位角误差放大,并在机身平时会引起倾角和方位角误差最大达0.85°;为消除误差,首先采用传统钻臂运动学误差补偿方法建立了钻臂静、动态误差补偿模型,利用全站仪测试关节间隙和变形量,基于补偿模型和RBF神经网络法求逆解得到误差补偿量,钻臂期望位姿与实际位姿误差的x方向平均误差为9.6 mm,y方向平均误差为18.2 mm,z方向平均误差为16 mm,满足工程应用要求;其次为解决传统全站仪试验测量的方法的复杂性和非实时性问题,提出了一种通过激光测距仪和高精度开孔定向仪组合获得位姿误差检测的方法,通过测距实时计算实际和理论倾角、方位角差值,作为误差补偿后的新倾角和方位角的控制输入量,对钻臂进行实时误差检测与补偿;最后利用传统全站仪精度检测方法对激光测距组合位姿误差补偿模型进行验证。试验表明:激光测距组合定位误差检测法最大误差差值在±0.5°以内,方位角最大误差在±0.5°以内,比未采用误差补偿前分别提高了41.1%和37.5%,满足了钻孔机器人开孔定位误差要求。在煤炭行业开展了钻孔机器人钻臂在线精确定位与误差补偿研究,对钻孔机器人精确自动开孔定位及孔群全自动施工具有重要的借鉴和指导意义。