Pairing of the viscera and bowels is an important theory,which provides guidance to traditional Chinese medicine(TCM) clinical practice.Investigating this theory has been the focus of research on the basic theory of T...Pairing of the viscera and bowels is an important theory,which provides guidance to traditional Chinese medicine(TCM) clinical practice.Investigating this theory has been the focus of research on the basic theory of TCM.Recently,researchers have performed many studies on the theory that the lung and large intestine are exterior-interiorly related,which is a different point of view to that of previous literature,recent clinical studies and experimental studies,and these recent studies have enforced the theoretical connotation of the statement.However,there are problems in some of these studies including recent clinical studies and experimental studies.In the current article,literature on the viscera-related theory of the lung and large intestine are exterior-interiorly related is reviewed from physiological,pathological,and clinical views,and some opinions on the current research status are discussed.展开更多
Objective: To analyze the similarities and differences of the applications of "the lung and large intestine being interior-exteriorly related"between the ancient and modern clinical practices, and to reveal ...Objective: To analyze the similarities and differences of the applications of "the lung and large intestine being interior-exteriorly related"between the ancient and modern clinical practices, and to reveal the theory meaning.Method: Based on the ancient and modern medical cases database, 245 ancient medical records and 373 modern medical records were studied with the general statistical description and analysis of association rules, and the results were compared to summarize the similarities and differences of the regular pattern of syndrome and treatment on lung-large intestine related diseases in ancient and modern medical records.Results: In modern medical cases, intestinal diseases appeared with the main symptom of constipation due to deficiency of lung qi and qi stagnation of large intestine were always treated by purgation together with replenishing and restoring lung qi. In ancient medical cases, large intestine heat was always caused by lung heat and a variety of diarrhea symptoms appeared. They were always treated by clearing heat and moistening lungs. In addition, the symptom of bound stool caused by qi stagnation of large intestine due to lung qi stagnation was always treated by lowering lung qi to regulate and smooth large intestine qi. And Armeniae Amarum Semen was used by both as a core medicinal herb.Conclusion: Ascending-descending of qi movement is the core of the lung and large intestine relationship. In other words, the lung and the large intestine communicate through qi.展开更多
目的分析“肺与大肠相表里”相关研究热点和趋势,为该理论传承及创新提供参考。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)、Web of Science、PubMed、Emb...目的分析“肺与大肠相表里”相关研究热点和趋势,为该理论传承及创新提供参考。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)、Web of Science、PubMed、Embase建库至2022年12月31日收录的“肺与大肠相表里”研究中英文文献。运用CiteSpace6.1.R2和VOSviewer1.6.18软件对发文量、来源期刊、作者、机构、关键词进行可视化分析。结果共纳入中文文献661篇和英文文献125篇,中文文献发文量呈波动上升趋势,英文文献呈稳定上升趋势。中文文献发文较多的期刊有《辽宁中医杂志》《中华中医药杂志》《世界中医药》,英文文献发文较多的期刊有Chinese Journal of Integrative Medicine、Journal of Ethnopharmacol、Evidence-Based Complementary and Alternative Medicine。北京中医药大学高思华团队、李宇航团队及成都中医药大学杨宇团队发文较多;关键词分析表明,高频关键词有便秘、肺肠同治、肠道菌群、慢性阻塞性肺疾病、溃疡性结肠炎等,主要涉及疾病、理论探讨、实验研究等方面,其中肠道菌群、黏膜免疫、肺肠轴相关研究较持续。结论近年来“肺与大肠相表里”相关研究热度增加,研究团队初具规模,研究疾病主要围绕胃肠功能障碍、便秘、慢性阻塞性肺疾病、溃疡性结肠炎等,运用的方剂主要有宣白承气汤、大承气汤,肠道菌群和黏膜免疫是目前研究的热点机制。展开更多
目的分析国内外“肺肠同治”相关研究现状及发展趋势,为中医理论的传承与创新提供参考。方法以中国知网(CNKI)、Web of Science(WOS)核心数据库为数据来源,搜集2000年以来“肺肠同治”相关理论探讨和实际应用文献,采用VOSviewer和CiteSp...目的分析国内外“肺肠同治”相关研究现状及发展趋势,为中医理论的传承与创新提供参考。方法以中国知网(CNKI)、Web of Science(WOS)核心数据库为数据来源,搜集2000年以来“肺肠同治”相关理论探讨和实际应用文献,采用VOSviewer和CiteSpace软件对发文时间、期刊、地域分布、关键词等进行可视化分析。结果共纳入中文文献751篇、英文文献384篇,发文量整体呈上升趋势,2015年后进入快速发展期。发文量排名第一的中文和英文期刊分别为《中华中医药杂志》(38篇)、Frontiers in Immunology(25篇)。北京中医药大学是中文文献发文量最高的机构(90篇),并与16家机构存在紧密的合作关系;英文文献发文量最高的机构为Institut National de la Sante et de la Recherche Medicale(12篇)和University of California System(12篇)。基于VOSviewer中文关键词形成12个聚类、英文关键词形成7个聚类,研究热点主要集中在经典理论挖掘、肺肠相关疾病、方药、机制探索、相关因子等方面。结论“肺肠同治”研究呈上升发展趋势,预测未来研究热点及前沿仍在肠-肺轴、肺肠微生物等方面。不同机构间应加强和深化合作、促进学术交流,注重运用现代科技手段研究中医理论,促进中医药理论的国际传播。展开更多
OBJECTIVE:To analyze the application laws of clinical drugs by descriptive statistical method with the clinical literatures guided by "lung being connected with large intestine" used as the object.METHODS:Re...OBJECTIVE:To analyze the application laws of clinical drugs by descriptive statistical method with the clinical literatures guided by "lung being connected with large intestine" used as the object.METHODS:Retrievepubliclypublishedclinicalliteratures about "lung being connected with large intestine"inrecent30years,establishthedatabaseofclinical literature,and study on the clinically drug-used lawsbydescriptivestatisticalanalyticmethod.RESULTS:The common high frequent drugs used for the lung-intestine related diseases were Gualou(Ructus Trichsanthis),Dahuang(Radix et Rhizoma),Kuxingren(Semen Armeniacae Amarum),Gancao(Radix Glycyrrhizae),Houpu(Cortex Magnoliae Officinalis),Zhishi(Fructus Aurantii Immaturus).For the different clinical syndrome types,in the commonly used drugs there were different characteristics,reflecting the principle of TCM syndrome differentiation treatment.CONCLUSION:The common high frequent drugs used for the lung-intestine related diseases are Gualou(Fructus Trichsanthis),Dahuang(Radix et Rhizoma),Kuxingren(Semen Armeniacae Amarum),Gancao(Radix Glycyrrhizae),Houpu(Cortex Magnoliae Officinalis),Zhishi(Fructus Aurantii Immaturus),which are commonly-used drugs for the lung-intestine related diseases,with differences for different syndrome types.展开更多
基金Supported by National Key Basic Research and Development Program "The research of literature review and comprehensive analysis on the theory of lung and large intestine are exterior-interior related"(No.2009CB522701)
文摘Pairing of the viscera and bowels is an important theory,which provides guidance to traditional Chinese medicine(TCM) clinical practice.Investigating this theory has been the focus of research on the basic theory of TCM.Recently,researchers have performed many studies on the theory that the lung and large intestine are exterior-interiorly related,which is a different point of view to that of previous literature,recent clinical studies and experimental studies,and these recent studies have enforced the theoretical connotation of the statement.However,there are problems in some of these studies including recent clinical studies and experimental studies.In the current article,literature on the viscera-related theory of the lung and large intestine are exterior-interiorly related is reviewed from physiological,pathological,and clinical views,and some opinions on the current research status are discussed.
基金supported by National Key Basic Research and Development Program "The research of literature review and comprehensive analysis on the theory of lung and large intestine are exterior-interior related"(No.2009CB522701)
文摘Objective: To analyze the similarities and differences of the applications of "the lung and large intestine being interior-exteriorly related"between the ancient and modern clinical practices, and to reveal the theory meaning.Method: Based on the ancient and modern medical cases database, 245 ancient medical records and 373 modern medical records were studied with the general statistical description and analysis of association rules, and the results were compared to summarize the similarities and differences of the regular pattern of syndrome and treatment on lung-large intestine related diseases in ancient and modern medical records.Results: In modern medical cases, intestinal diseases appeared with the main symptom of constipation due to deficiency of lung qi and qi stagnation of large intestine were always treated by purgation together with replenishing and restoring lung qi. In ancient medical cases, large intestine heat was always caused by lung heat and a variety of diarrhea symptoms appeared. They were always treated by clearing heat and moistening lungs. In addition, the symptom of bound stool caused by qi stagnation of large intestine due to lung qi stagnation was always treated by lowering lung qi to regulate and smooth large intestine qi. And Armeniae Amarum Semen was used by both as a core medicinal herb.Conclusion: Ascending-descending of qi movement is the core of the lung and large intestine relationship. In other words, the lung and the large intestine communicate through qi.
文摘目的分析“肺与大肠相表里”相关研究热点和趋势,为该理论传承及创新提供参考。方法检索中国知识资源总库(CNKI)、中文科技期刊数据库(VIP)、中国学术期刊数据库(万方数据)、中国生物医学文献数据库(CBM)、Web of Science、PubMed、Embase建库至2022年12月31日收录的“肺与大肠相表里”研究中英文文献。运用CiteSpace6.1.R2和VOSviewer1.6.18软件对发文量、来源期刊、作者、机构、关键词进行可视化分析。结果共纳入中文文献661篇和英文文献125篇,中文文献发文量呈波动上升趋势,英文文献呈稳定上升趋势。中文文献发文较多的期刊有《辽宁中医杂志》《中华中医药杂志》《世界中医药》,英文文献发文较多的期刊有Chinese Journal of Integrative Medicine、Journal of Ethnopharmacol、Evidence-Based Complementary and Alternative Medicine。北京中医药大学高思华团队、李宇航团队及成都中医药大学杨宇团队发文较多;关键词分析表明,高频关键词有便秘、肺肠同治、肠道菌群、慢性阻塞性肺疾病、溃疡性结肠炎等,主要涉及疾病、理论探讨、实验研究等方面,其中肠道菌群、黏膜免疫、肺肠轴相关研究较持续。结论近年来“肺与大肠相表里”相关研究热度增加,研究团队初具规模,研究疾病主要围绕胃肠功能障碍、便秘、慢性阻塞性肺疾病、溃疡性结肠炎等,运用的方剂主要有宣白承气汤、大承气汤,肠道菌群和黏膜免疫是目前研究的热点机制。
文摘目的分析国内外“肺肠同治”相关研究现状及发展趋势,为中医理论的传承与创新提供参考。方法以中国知网(CNKI)、Web of Science(WOS)核心数据库为数据来源,搜集2000年以来“肺肠同治”相关理论探讨和实际应用文献,采用VOSviewer和CiteSpace软件对发文时间、期刊、地域分布、关键词等进行可视化分析。结果共纳入中文文献751篇、英文文献384篇,发文量整体呈上升趋势,2015年后进入快速发展期。发文量排名第一的中文和英文期刊分别为《中华中医药杂志》(38篇)、Frontiers in Immunology(25篇)。北京中医药大学是中文文献发文量最高的机构(90篇),并与16家机构存在紧密的合作关系;英文文献发文量最高的机构为Institut National de la Sante et de la Recherche Medicale(12篇)和University of California System(12篇)。基于VOSviewer中文关键词形成12个聚类、英文关键词形成7个聚类,研究热点主要集中在经典理论挖掘、肺肠相关疾病、方药、机制探索、相关因子等方面。结论“肺肠同治”研究呈上升发展趋势,预测未来研究热点及前沿仍在肠-肺轴、肺肠微生物等方面。不同机构间应加强和深化合作、促进学术交流,注重运用现代科技手段研究中医理论,促进中医药理论的国际传播。
基金Supported by National Key Basic Research Development Plan(N0.2009CB522701)Anhui Natural Science foundation(N0.090416246)
文摘OBJECTIVE:To analyze the application laws of clinical drugs by descriptive statistical method with the clinical literatures guided by "lung being connected with large intestine" used as the object.METHODS:Retrievepubliclypublishedclinicalliteratures about "lung being connected with large intestine"inrecent30years,establishthedatabaseofclinical literature,and study on the clinically drug-used lawsbydescriptivestatisticalanalyticmethod.RESULTS:The common high frequent drugs used for the lung-intestine related diseases were Gualou(Ructus Trichsanthis),Dahuang(Radix et Rhizoma),Kuxingren(Semen Armeniacae Amarum),Gancao(Radix Glycyrrhizae),Houpu(Cortex Magnoliae Officinalis),Zhishi(Fructus Aurantii Immaturus).For the different clinical syndrome types,in the commonly used drugs there were different characteristics,reflecting the principle of TCM syndrome differentiation treatment.CONCLUSION:The common high frequent drugs used for the lung-intestine related diseases are Gualou(Fructus Trichsanthis),Dahuang(Radix et Rhizoma),Kuxingren(Semen Armeniacae Amarum),Gancao(Radix Glycyrrhizae),Houpu(Cortex Magnoliae Officinalis),Zhishi(Fructus Aurantii Immaturus),which are commonly-used drugs for the lung-intestine related diseases,with differences for different syndrome types.
