Comprehensive Benefit Evaluation Method of Mountain Flood Disaster Prevention and Control in Jiangxi Province Based on Matter-Element Extension Model

Taking the mountain flood disaster prevention and control project in Jiangxi province as the research object, the evaluation period is 2010-2015, and 29 evaluation indexes are selected from 7 aspects. In this paper, game theory is introduced to optimize the subjective and objective weights of the index, and the comprehensive weights are obtained by normalization. The results show that the eigenvalues of the grade variables of benefit evaluation decreased from 3.43 to 2.03, indicating that the project of mountain flood disaster prevention and control in Jiangxi province brings into play the benefits year by year, and the eigenvalues tend to decrease steadily after 2012, it is consistent with the changes of various engineering measures and non-engineering measures in the project.

Evaluation on Urban Land Ecological Security Based on the PSR Model and Matter-Element Analysis: A Case Study of Zhuhai, Guangdong, China

As one of the Special Economic Zones since the reform and opening up, Zhuhai has developed during the past 30 years. Its economic development, industrial structure and ecological environment have undergone great changes. Research on changes in Zhuhai’s land ecological security is of great significance. Using relevant data from 2007-2012, this study established a land ecological security assessment system based on the PSR conceptual framework model. The system contained 18 indicators from 3 aspects according to the concrete features of Zhuhai. Then we used the matterelement analysis and the improved entropy weight to analyze and evaluate the land ecological security of Zhuhai. The results showed that: from 2007 to 2012, the levels of the land ecological security of Zhuhai were “secure”, and the value increased year by year;as the land ecological security response value increased, Zhuhai was capable of solving land ecosystem problems. However, it should be noted that the structure of land ecosystem in Zhuhai has not formed and that rapid expansion of construction land has caused the shortage of cultivated land and other issues. Measures should be taken to control the construction area, improve land intensive utilization and improve the land ecological security.

Application of Matter-element Model in Soil Nutrient Evaluation of Ecological Fragile Region

On the basis of the soil environment investigation in Da＇an City, Jilin Province, China, 40 soil samples from main land use types were obtained and tested by standard method. Soil organic matter （SOM）, total N （TN）, total P （TP）, total K （TK）, available N （AN）, available P （AP） and available K （AK） were chosen as the evaluation factors. A regional soil nutrient evaluation model was developed based on the matter-element model. The results show that the soil samples with nutrient grade Ⅱ-Ⅴ respectively account for 10%, 30%, 32.5% and 27.5%, and those with grade Ⅳ and Ⅴ account for 60% in all samples. The relationship between soil nutrients and land types indicates that the nutrients of farmland are relatively good, with 41.7% of soil samples with the nutrient grade Ⅳ and Ⅴ. The nutrients of saline-alkali land and sandy land are the worst, with 100% of soil samples with the nutrient grade IV and V. And the ratios of soil samples grade IV and V in grassland and wasteland are respectively 62.5 % and 54.55%. Generally speaking, the soil nutrients status in Da＇an City is poor, 60% of soil samples are in poor and extremely poor conditions, indicating that the soil has been severely eroded. Being a relatively superior evaluation method with more accurate resuits and spatial distribution consistency, matter-element analysis is more suitable for regional soil nutrient evaluation than previous models.

Evaluation model of venture investment based on fuzzy matter-element method of combined weight

An evaluation model of an international venture investment project on the basis of fuzzy matter-element and combined weight methods is introduced. First, the compound fuzzy matter-element of optimal subordinate degree is constructed on the principle of the bigger-more-optimal or the less-more-optimal depending on the actual evaluation indicators, and combined with standard fuzzy matter-element to form a difference-square fuzzy matter-element. Secondly, a combined weight is calculated by both information entropy and the expert grading method. Finally, the compound fuzzy matter-element of Euclidian approach degree by M(·,+)method is constituted and used to classify venture investment projects. Based on the model above, six venture investment projects in a company are evaluated, and the results show that the projects are all good, which is demonstrated by the good income of the projects. Therefore, the coincidence of evaluation results and actual operation status indicates that the model is of great value in practical application.

Carrying capacity of water environment in public tourism resources based on matter-element model

When water environmental carrying capacity of public resource tourist attraction is studied, the two action subjects of tourists and local residents should be discussed, and comprehensive consideration must be given to the influence of these two on water environment. On the basis of water resource carrying capacity and water quality carrying capacity, water environmental carrying capacity index of public resource tourist attraction was constructed, the model for the water environmental carrying capacity of public resource tourist attraction was established on the basis of matter-element model and analytical hierarchy process. By applying this method, water environmental carrying capacity situation of a certain public resource tourist attraction can be gained, moreover, situations about several aspects of water environmental carrying capacity can be evaluated.

Matter-elements model and application for prediction of ccoal and gas outburst

The theory and method of extenics were applied to establish classical field matterelements and segment field matter elements for coal and gas outburst.A matter-element model for prediction was established based on five matter-elements,which includedgas pressure,types of coal damage,coal rigidity,initial speed of methane diffusionand in-situ stress.Each index weight was given fairly and quickly through the improvedanalytic hierarchy process,which need not carry on consistency checks,so accuracy ofassessment can be improved.

Matter-element models for comprehensive earthquake predication and their applications

Extenics was a branch of mathematics for studying the incompatible problems. In this paper, basing on calculating the associative functions of all various indexes, we have obtained the quantitative assessment results of prediction indexes by introducing this theory into the comprehensive earthquake prediction through establishing the matter-element model for comprehensive prediction, so that the incompatible problems can be solved. The preliminary results demonstrate that this method has better prospects in comprehensive earthquake prediction.

Evaluation of the eco-environmental frangibility in west Jilin Province based on the matter-element model

The west Jilin Province is a typical area in the ecotone between agriculture and animal husbandry,with a frangible eco-environment.With respect to the three aspects of water resource,natural disasters and land degradation,10 indices were selected to establish a matter-element model for the assessment of eco-environmental frangibility in the west Jilin Province.The results indicate that during 1985–2000,Qian’an,Fuyu,and Changling had the least frangibility(level Ⅰ),followed by Da’an and Qianguo(level Ⅱ),and Taobei,Zhenlai,Taonan,and Tongyu had the highest frangibility(level Ⅲ).On the whole,the counties in Songyuan city were less frangible than those in Baicheng city.Different counties had different frangibilities to environmental factors,e.g.,Da’an and Tongyu were frangible in water resource conditions;Taobei,Zhenlai,Taonan,Tongyu and Qian’an suffered most from natural disasters;while Taobei,Taonan and Qianguo were threatened by severe land degradation.

Expert Anti-Evaluation Model Based on Matter-Element Analysis in Fund Project Peer-Review System

The article analyses several key issues which restrict the effectiveness of fund project peer review work. It analyses the evaluating theory and matter-element theory to access the expert anti-evaluation model, and also studies the expert anti-evaluation index system to support the anti-evaluation method. The practical basis is the true score data of the experts which is collected from the actual anti-evaluation in Liaoning province science and technology fund project peer review system. With the practical experience of the actual project, we prove that the expert index system anti-evaluation model and expert anti-evaluation method can improve the fund project peer review work and play a positive role for the peer review work and also make the review work more scientific and more rational.

River Health Assessment Based on Fuzzy Matter-element Model

[Objective] The study aimed to assess the health state of rivers by using fuzzy matter-element model.[Method] Based on fuzzy matter-element analysis theory,the assessment model of river health was established,then a modified method to calculate the superior subordinate degree was put forward according to Hamming distance.Afterwards,a multi-level evaluation model,which contained the assessment indicators about hydrological features,ecological characteristics,environmental traits and service function,was set up based on this method above.Finally,the model was applied in the health assessment of Qinhuai River.[Result] The health state of Qinhuai River was at medium level.This assessment result was consistent with that of comprehensive index method,and it showed that the multi-level fuzzy matter-element model was effective in the assessment of river health.[Conclusion] The research provided an effective method to evaluate the state of river health.

Evaluation of Social Environment Impact of Highway Construction Using Gray Matter-Element Information Entropy Model

Due to the importance of the social environment impact of highway construction project, an advanced evaluation is required to incorporate situations such as uncertainty, incompatibility and less information. This paper proposes a gray matter-element evaluation model based on the information entropy. The model is developed by combining both quantitative and qualitative methods, using probability theory to convert quantitative index to qualitative index, and the weight of those indexes were determined through synthesised integral weighting method, integrating matter-element theory, grey theory, and information theory. The model is then applied to evaluate the impact of the social environmental impact of highway construction project which will provide support for decision makers. Cheng-Yu highway and Shen-Da highway were selected for model application, and good results were achieved similar to the real situation.

Optimizing selection of bridge raft based on fuzzy matter-element model and combination weighting

It＇ s a necessary selection to support the maneuver across Yangtze River by floating bridge constructed by portable steel bridge and civilian ships. It is a comprehensive index for the scheme of bridge raft, containing a variety of technical factors and uncertainties. The optimization is the selection in the constructing time, quantity of equipments and man power. Based on the calculation result of bridge rafts, an evaluating system is established, consisting of index of spacing between interior bays, raft length, truss numbers, operation difficulty and maximal bending stress. A fuzzy matter element model of optimizing selection of bridge rafts was built up by combining quantitative analysis with qualitative analysis. The method of combination weighting was used to calculate the value of weights index to reduce the subjective randomness. The sequence of schemes and the optimization resuh were gained finally based on euclid approach degree. The application result shows that it is simple and practical.

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis

Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor dysfunction.To date,no effective treatment exists as the exact causative mechanism remains unknown.Therefore,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic targets.Since most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets astrocytes.These experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum disorders.In this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model choices.In addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.

Failure model of environmental PPP project based on extension matter-element theory

In recent years,with the global environmental pollution becoming more and more serious,and the widespread application of PPP model in various fields,PPP model provides a new solution for environmental governance.However,due to environmental management of PPP projects in practice by various factors,such as the lack of social value,organizational management confusion and consultation communication is not in place cause group events,resulting in the failure of the PPP project,and a large number of economic losses.Therefore,the objective of this paper is to ensure the smooth implementation of environmental management of PPP projects,to reduce the risk to avoid failure.The research methods adopted in this study include literature review and case analysis,based on the theory of environmental governance PPP,select 15 failure cases analysis failure reasons,identify environmental management PPP project’s 18 failure factors,starting from the government to enterprises.The index is divided into three dimensions:social system,organization and management,public behavior,and determination of failure measure index system.Based on the theory of the open matter,the failure measure model is established,and the failure factor index is measured and analyzed.The degree of failure of the project is clarified and the PPP project is analyzed by a sewage treatment to verify the reasonable model of the failure measure model.The feasibility of the future of environmental management PPP project failure risk provides a practical tool.

Exploiting fly models to investigate rare human neurological disorders

Rare neurological diseases,while individually are rare,collectively impact millions globally,leading to diverse and often severe neurological symptoms.Often attributed to genetic mutations that disrupt protein function or structure,understanding their genetic basis is crucial for accurate diagnosis and targeted therapies.To investigate the underlying pathogenesis of these conditions,researchers often use non-mammalian model organisms,such as Drosophila(fruit flies),which is valued for their genetic manipulability,cost-efficiency,and preservation of genes and biological functions across evolutionary time.Genetic tools available in Drosophila,including CRISPR-Cas9,offer a means to manipulate gene expression,allowing for a deep exploration of the genetic underpinnings of rare neurological diseases.Drosophila boasts a versatile genetic toolkit,rapid generation turnover,and ease of large-scale experimentation,making it an invaluable resource for identifying potential drug candidates.Researchers can expose flies carrying disease-associated mutations to various compounds,rapidly pinpointing promising therapeutic agents for further investigation in mammalian models and,ultimately,clinical trials.In this comprehensive review,we explore rare neurological diseases where fly research has significantly contributed to our understanding of their genetic basis,pathophysiology,and potential therapeutic implications.We discuss rare diseases associated with both neuron-expressed and glial-expressed genes.Specific cases include mutations in CDK19 resulting in epilepsy and developmental delay,mutations in TIAM1 leading to a neurodevelopmental disorder with seizures and language delay,and mutations in IRF2BPL causing seizures,a neurodevelopmental disorder with regression,loss of speech,and abnormal movements.And we explore mutations in EMC1 related to cerebellar atrophy,visual impairment,psychomotor retardation,and gain-of-function mutations in ACOX1 causing Mitchell syndrome.Loss-of-function mutations in ACOX1 result in ACOX1 deficiency,characterized by very-long-chain fatty acid accumulation and glial degeneration.Notably,this review highlights how modeling these diseases in Drosophila has provided valuable insights into their pathophysiology,offering a platform for the rapid identification of potential therapeutic interventions.Rare neurological diseases involve a wide range of expression systems,and sometimes common phenotypes can be found among different genes that cause abnormalities in neurons or glia.Furthermore,mutations within the same gene may result in varying functional outcomes,such as complete loss of function,partial loss of function,or gain-of-function mutations.The phenotypes observed in patients can differ significantly,underscoring the complexity of these conditions.In conclusion,Drosophila represents an indispensable and cost-effective tool for investigating rare neurological diseases.By facilitating the modeling of these conditions,Drosophila contributes to a deeper understanding of their genetic basis,pathophysiology,and potential therapies.This approach accelerates the discovery of promising drug candidates,ultimately benefiting patients affected by these complex and understudied diseases.

A promising approach for quantifying focal stroke modeling and assessing stroke progression:optical resolution photoacoustic microscopy photothrombosis

To investigate the mechanisms underlying the onset and progression of ischemic stroke,some methods have been proposed that can simultaneously monitor and create embolisms in the animal cerebral cortex.However,these methods often require complex systems and the effect of age on cerebral embolism has not been adequately studied,although ischemic stroke is strongly age-related.In this study,we propose an optical-resolution photoacoustic microscopy-based visualized photothrombosis methodology to create and monitor ischemic stroke in mice simultaneously using a 532 nm pulsed laser.We observed the molding process in mice of different ages and presented age-dependent vascular embolism differentiation.Moreover,we integrated optical coherence tomography angiography to investigate age-associated trends in cerebrovascular variability following a stroke.Our imaging data and quantitative analyses underscore the differential cerebrovascular responses to stroke in mice of different ages,thereby highlighting the technique's potential for evaluating cerebrovascular health and unraveling age-related mechanisms involved in ischemic strokes.

Reduced mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor contributes to neurodegeneration in a model of spinal and bulbar muscular atrophy pathology

Spinal and bulbar muscular atrophy is a neurodegenerative disease caused by extended CAG trinucleotide repeats in the androgen receptor gene,which encodes a ligand-dependent transcription facto r.The mutant androgen receptor protein,characterized by polyglutamine expansion,is prone to misfolding and forms aggregates in both the nucleus and cytoplasm in the brain in spinal and bulbar muscular atrophy patients.These aggregates alter protein-protein interactions and compromise transcriptional activity.In this study,we reported that in both cultured N2a cells and mouse brain,mutant androgen receptor with polyglutamine expansion causes reduced expression of mesencephalic astrocyte-de rived neurotrophic factor.Overexpressio n of mesencephalic astrocyte-derived neurotrophic factor amelio rated the neurotoxicity of mutant androgen receptor through the inhibition of mutant androgen receptor aggregation.Conversely.knocking down endogenous mesencephalic astrocyte-derived neurotrophic factor in the mouse brain exacerbated neuronal damage and mutant androgen receptor aggregation.Our findings suggest that inhibition of mesencephalic astrocyte-derived neurotrophic factor expression by mutant androgen receptor is a potential mechanism underlying neurodegeneration in spinal and bulbar muscular atrophy.

基于Fuzzy Matter-Element模型的电力上市公司财务核心竞争能力评价

鉴于电力上市公司财务核心竞争能力评价的复杂性以及单项指标评价结果的不相容性,本文在模糊物元分析的基础上,将熵权的理论方法与海明贴近度的概念相结合,建立了电力上市公司财务核心竞争能力评价的模糊物元模型。把不同电力企业作为物元的事物,以它们的各项评价指标及相应的模糊量值构造模糊物元,通过计算与理想模糊物元之间的海明贴近度,实现对上市电力公司财务核心竞争能力的综合评价。

采用STAMP-24Model的多组织事故分析

安全生产事故往往由多组织交互、多因素耦合造成,事故原因涉及多个组织。为预防和遏制多组织生产安全事故的发生,基于系统理论事故建模与过程模型(Systems-Theory Accident Modeling and Process,STAMP)、24Model,构建一种用于多组织事故分析的方法,并以青岛石油爆炸事故为例进行事故原因分析。结果显示:STAMP-24Model可以分组织,分层次且有效、全面、详细地分析涉及多个组织的事故原因,探究多组织之间的交互关系;对事故进行动态演化分析,可得到各组织不安全动作耦合关系与形成的事故失效链及管控失效路径,进而为预防多组织事故提供思路和参考。