Development of a new cerebral ischemia reperfusion model of Mongolian gerbils and standardized evaluation system

Background:The Mongolian gerbil is an excellent laboratory animal for preparing the cerebral ischemia model due to its inherent deficiency in the circle of Willis.However,the low incidence and unpredictability of symptoms are caused by numerous complex variant types of the circle.Additionally,the lack of an evaluation system for the cer-ebral ischemia/reperfusion(I/R)model of gerbils has shackled the application of this model.Methods:We created a symptom-oriented principle and detailed neurobehavioral scoring criteria.At different time points of reperfusion,we analyzed the alteration in locomotion by rotarod test and grip force score,infarct volume by triphenyltetrazo-lium chloride(TTC)staining,neuron loss using Nissl staining,and histological charac-teristics using hematoxylin-eosin(H&E)straining.Results:With a successful model rate of 56%,32 of the 57 gerbils operated by our method harbored typical features of cerebral I/R injury,and the mortality rate in the male gerbils was significantly higher than that in the female gerbils.The suc-cessfully prepared I/R gerbils demonstrated a significant reduction in motility and grip strength at 1 day after reperfusion;formed obvious infarction;exhibited typi-cal pathological features,such as tissue edema,neuronal atrophy and death,and vacuolated structures;and were partially recovered with the extension of reperfu-sion time.Conclusion:This study developed a new method for the unilateral common carotid artery ligation I/R model of gerbil and established a standardized evaluation system for this model,which could provide a new cerebral I/R model of gerbils with more practical applications.

Professional Development of County-level Physical Education Teachers from the Perspective of the New Curriculum Standards:A Case Study of Huaiji County

Using methods such as questionnaire survey and literature review,a survey was conducted on the professional development of physical education teachers in Huaiji County under the background of the new curriculum standards.The research results found that physical education teachers in Huaiji County have a relatively good distribution structure in terms of teaching experience,age,and education level,but the gender ratio and professional title ratio need to be improved.In terms of professional competence,teachers have shown good performance in teaching implementation ability,but there is still room for improvement in teaching design ability.A certain proportion of teachers still express dissatisfaction with professional title promotion,hardware configuration satisfaction,salary and benefits,and school reward mechanisms.Based on this,this study proposes some measures to improve the professional development level of county-level physical education teachers,such as enhancing teachers teaching design and implementation abilities,strengthening the cultivation of technical action demonstration abilities,improving hardware configuration satisfaction and teaching effectiveness reflection level,strengthening guidance and support for teachers professional development,and enhancing the promotion and implementation of post employment training.

Research on Key Points of Design of Standard Plants in Modern Industrial Parks Under the Background of Promoting the Development of New Quality Productive Forces

With the progress of science and technology and the acceleration of industrialization,the modern industrial park is an important carrier of industrial development.The importance of its standard plant design has become increasingly prominent.With the development of new quality productive forces as the background,this research deeply discusses the key points of standard plant design in modern industrial parks.This paper uses literature review and case analysis to systematically analyze the important role of standard plant design in developing new quality productive forces in modern industrial parks and puts forward suggestions for optimizing design.It is found that the rationality,intelligence,and environmental protection of plant design are the key factors affecting the development of new quality productive forces.The paper summarizes the core points of modern industrial park standard plant design to provide a reference for the future development of related industries.

Issues and Countermeasures in Chinese FLTRP Primary School Textbooks under the New Curriculum Standard

The New Curriculum Standard(NCS)is the norm and quality requirement of the Chinese national educational curriculum as well as the basis of teaching management,curriculum evaluation,and textbook compilation.In textbook design,the selection of textbook materials should meet the objectives and requirements of the NCS.Since appropriate teaching materials are essential to curriculum standards and effective teaching,we must follow the consistency between textbook materials and curriculum standards to achieve an ideal degree of conformity with the textbook system and teaching objectives and promote the sustainable development of the English curriculum reform.However,the current primary school English textbooks fall short of the NCS,which leads to difficulties in implementing teaching tasks and achieving teaching goals.Given these difficulties,we should analyze the causes from three dimensions:linguistic knowledge,cultural awareness,and learning strategies.In addition,a high recurrence of phonetic knowledge,systematic grammar presentation,diversified learning styles,level grading,and in-depth involvement of cultural factors are keys to the perfect conformity of the NCS and English textbooks.

交互式数字叙事:加拿大Writing New Body Worlds阅读治疗新探索

文章基于相关研究文献与语料,对加拿大WNB阅读治疗实践进行梳理与归纳。WNB首次使用交互式数字叙事技术,构建面向公众的阅读治疗平台,以其交互式特征,融合了阅读和治疗引导两个过程,提供可访问的非临床方式,可面向大规模人群实现预防性健康干预。基于数据与计算的精准化阅读治疗是数字人文视角下的新变革,更具推广应用价值;以在线阅读平台建设为依托,推进实施平台化的阅读和治疗应成为未来发展方向之一;基于阅读形态与体验因技术赋能而改变的现状,图书馆应发挥引领作用,积极收集、创建或协助创建数字故事,推进阅读推广、服务与治疗的融合性发展,成为社区建设促进者、历史欣赏者和社区参与倡导者,也使阅读借助交互式数字叙事这一新载体,更好地发挥变革的力量,促进健康与幸福。

Thinking about Renewable Portfolio Standard to be Implemented in China

This paper briefs the basic objective of pursuing Renewable Portfolio Standard (RPS), puts forward a thinking about the scope and three modes of RPS-implementation in China and enumerates other possible measures, such as public bidding on concession, exemption from value-added tax, to promote wind power exploitation and development.

New formula for predicting standard liver volume in Chinese adults

AIM To obtain a reference range of morphological indices and establish a formula to accurately predict standard liver volume(SLV) in Chinese adults.METHODS Computed tomography(CT)-estimated total liver volume(CTLV) was determined in 369 Chinese adults. Age,sex,body weight,body height,body mass index,and body surface area(BSA) were recorded using CT. Total splenic volume,portal venous diameter(PVD),splenic venous diameter(SVD),and portal venous cross-sectional area(PVCSA) were also measured by CT. Stepwise multiple linear regression analysis was performed to evaluate the impact of each parameter on CTLV and to develop a new SLV formula. The accuracy of the new formula was compared with the existing formulas in a validation group.RESULTS The average CTLV was 1205.41 ± 257.53 cm3(range,593.80-2250.10 cm3). The average of PVD,SVD and PVCSA was 9.34 ± 1.51 mm,7.40 ± 1.31 mm and 173.22 ± 48.11 mm2,respectively. The CT-estimated splenic volume of healthy adults varied markedly(range,46.60-2892.30 cm3). Sex,age,body height,body weight,body mass index,and BSA were significantly correlated with CTLV. BSA showed the strongest correlation(r = 0.546,P < 0.001),and was used to establish a new model for calculating SLV: SLV(cm3) = 758.259 × BSA(m2)-124.272(R2 = 0.299,P < 0.001). This formula also predicted CTLV more accurately than the existing formulas,but overestimated CTLV in elderly subjects > 70 years of age,and underestimated liver volume when CTLV was > 1800 cm3.CONCLUSION Our new BSA-based formula is more accurate than other formulas in estimating SLV in Chinese adults.

New Insights into the Depositional Environments of Ordovician Carbonate Formations in the Yubei Area of Tarim Basin Based on Standard Microfacies Types

Objective The Yubei area is located in the mid-east Maigaiti slope of southwestern Tarim Basin, China, with an exploration history of several years. Recent exploration has preliminarily indicated that the Ordovician carbonate formations in this area have some oil and gas potential. Carbonate microfacies provides material basis for reservoir development, seal formation and hydrocarbon generation. Therefore, this work utilized the standard microfacies （SMF） types to study the microfacies of the Ordovician formations in the Yubei area in order to provide theoretical basis for the next exploration.

Progress and Challenges of Reference Standard and Its New Form: Digital Reference Standard

Number and quantities of reference standards (RS) needed for the quality control of drugs are increasing, bringing great pressure to the calibration and using company. This manuscript summarized the four generations for the development of RS including physical RS, paper atlas, substitute RS and electronic databases. The advantages and disadvantages of each generation were summarized. The concept of digital RS (DRS) was proposed based on this, and summed up the definition, advantages, and technical architecture of DRS. The 10 characteristics of five aspects of the DRS were discussed including digital, multi-dimension, big data, cloud computing, internet, internet of things, sharing, multi-terminal, intelligence, and compliance certification. Then, the necessity of its formation and application in the medicine holistic quality control of internet plus era was discussed in this manuscript.

The Impact of New Standard of Financial Instruments on Commercial Banks- A Case Study of Industrial and Commercial Bank of China

In July 2014,《International Financial Reporting Standard 9:Financial Instruments》(Referred to IFRS 9)was formally published. Compared to the former standard,《International Accounting Standard 39: Financial Instruments》(Referred to IAS 39), rules of two main aspects, the classification and measurement of financial assets and the impairment model of financial assets have been changed in IFRS 9. Taking ICBC as an example, this paper studies the impact of changes in financial instruments on commercial banks. The study shows three impacts on commercial banks’ financial report. Firstly, the changes of the classification and measurement of financial assets will have limited impacts on commercial banks. Secondly, the expected-loss model will significantly increase the loan loss reserves under the new standard, thus reducing the net asset and net profit. Thirdly, the change in the measurement way of the equity instruments of available-for-sale securities will increase the fluctuation of the net profit. This study shows investors and regulators the impact of the new standard of financial instruments on commercial banks.

New Thoughts on Standardization and Its Developmental Trend

The standardization community need to recognize the nature of standards. In the 199os, I put forward that standards are restraints by nature. First of all, those restraints are imposed by humans to create order and obtain benefits rather than being formed naturally. Secondly, they are good for development; otherwise, there is no necessity for its existence. Furthermore, they can bring both economical and social benefits. Finally, those restraints are characterized by specific methods, such as simplification （including serialization and universalization）, unification, modularization, routinization and comprehensive standardization. Standardization is how such restraints are implemented.

Cryptanalysis and Improvement of a New Certificateless Signature Scheme in the Standard Model

Digital signature,as an important cryptographic primitive,has been widely used in many application scenarios,such as e-commerce,authentication,cloud computing,and so on.Certificateless Public Key Cryptography(PKC)can get rid of the certificate management problem in the traditional Public Key Infrastructure(PKI)and eliminate the key-escrow problem in the identity-based PKC.Lately,a new Certificateless Signature(CLS)scheme has been proposed by Kyung-Ah Shim(IEEE SYSTEMS JOURNAL,2018,13(2)),which claimed to achieve provable security in the standard model.Unfortunately,we present a concrete attack to demonstrate that the scheme cannot defend against the Type I adversary.In this type of attack,the adversary can replace the public key of the signer,and then he plays the role of the signer to forge a legal certificateless signature on any message.Furthermore,we give an improved CLS scheme to resist such an attack.In terms of the efficiency and the signature length,the improved CLS is preferable to the original scheme and some recently proposed CLS schemes in the case of precomputation.

网络新媒体视阈下客家议题在日传播特征分析——基于日本Google News的考察

以日本Google News中的客家相关日文报道为语料,通过文本挖掘工具KH Coder进行文本数据挖掘,发现日本网络新闻媒体的客家议题日文报道具有分布零散性及以图片报道为主的特点。报道关注的客家区域主要涉及台湾地区、福建、香港地区、广东等地,其中,台湾地区的客家关注度最高。报道聚焦客家的观光旅游、产业振兴、客家书籍出版等相关内容,形成了客家传统建筑类、台湾地区客家文化交流类、客家文学作品推介类、客家观光旅游类等四大主要议题。本文提出要充分运用Google News等网络新媒体强大的技术功能和传播优势加大客家文化的传播力度。

Influences of population characteristics and natural resource endowment on renewable portfolio standard schedule design

Renewable portfolio standard （RPS） schedule requires a specified percentage of renewable electricity development by a specified date, and therefore directly determines the pace of renewable electricity in one area. The article aims to explore the ways the natural resource endowment and population characteristic affect the adoption of a RPS schedule. We used logistic regression to analyze the data of RPS dynamic schedules of 29 states and Washington, D.C. in the United States. Results show that local renewable potential and the interaction performance between citizen ideology and the league of conversation voters scoreboard are main factors affecting the choice of an RPS schedule, and the effect of the interaction performance between citizen ideology and LCV scoreboard has a higher significance. The finding suggests that strategies for developing renewable energy should be based on resources rather than economical level, and nublic education for environmental protection should be emphasized.

Thinking About the New Atmospheric Pollutant Emission Standard for Thermal Power Plants

China's new Atmospheric Pollutant Emission Standard for Thermal Power Plants has been made the most stringent atmospheric pollutant emission limit in the world,with the intensified control of nitrogen oxides in the air pollutants emitted by thermal power plants,the tightened limit on the emission of sulfur dioxide,and the widened range of control including mercury and other compounds discharge.The adoption of the new standard will considerably impact the survival and development of power plants,even the whole economy of the nation.While implementing all the policies and measures on emission reduction issued by the State to fulfill political,social,and economic responsibilities,China Huadian Corporation,one of the leading state-owned power generation groups,is actively exploring the green and low-carbon path for the sound and rapid development of the group.

New insights on the standardization of peripheral nerve regeneration quantitative analysis

Peripheral nerves form a complex network connecting the central nervous system and the body. Injuries to peripheral nerves often lead to partial or complete loss of motor, sen- sory and autonomic functions, thus interfering with many aspects of an individual＇s life.

A New Model for Calculation of Standard Entropies of Solid Compounds Ⅳ-Calculation of Standard Entropies of Solid Complex Silicates S

This paper presents a new model for the calculation of the standard entropies of solidcomplex silicates as follows.4. =53.63+9914-72.81 J/kmol (R=0.9915, Sd=5.39)Sixty complex silicates have been investigated, and good agreement was found between theestimated and experimental entropy values.

THE NEW MODEL FOR CALCULATION OF STANDARD ENTROPIES OF SOLID COMPOUNDS Ⅲ CALCULATION FOR STANDARD ENTROPIES OF SOLID BINARY OXIDES

This paper establishes a new model for calculation of the standard entropies of solid binary oxides as follows: S_(29)=27.07×Φ_1+1.120×Φ_2+n_1×k×Φ, -22.19 e.u (R=0.9960) We have invesigated 103 binary oxides. and found good agreemenl between estimated and experimental entropies.

A New Method for Impossible Differential Cryptanalysis of 8-Round Advanced Encryption Standard

This paper first presents an impossible differential property for 5-round Advanced Encryption Standard （AES） with high probability. Based on the property and the impossible differential cryptanalytic method for the 5-round AES, a new method is proposed for cryptanalyzing the 8-round AES-192 and AES-256. This attack on the reduced 8-round AES-192 demands 2^121 words of memory, and performs 2^148 8-round AES-192 encryptions. This attack on the reduced 8-round AES-256 demands 2^153 words of memory, and performs 2^180 8-round AES-256 encryptions. Furthermore, both AES-192 and AES-256 require about 2^98 chosen plaintexts for this attack, and have the same probability that is only 2^-3 to fail to recover the secret key.

An Empirical Study of the Effect of Inquiry Teaching on the Development of High School Students'Critical Thinking Under the New Curriculum Standards

The Ministry of Education of the People’s Republic of China has issued three guideline documents to encourage inquiry teaching to help students develop their ability to question,which is a defining feature of critical thinking.Two of the documents have clearly stated that English subject teaching should focus on building students’thinking capacity.Critical thinking is an essential feature of building thinking capacity and a key element of the core competencies the English subject seeks to cultivate.This research measures the performance of students of two high school classes in the exams conducted at the beginning,in the middle,and at the end of the experiment period during which inquiry teaching was applied to enhance students’critical thinking ability.The experiment results show that inquiry teaching can improve students’academic performance in English study and help them better develop their language skills.The implementation of the inquiry design in teaching listening,reading,and writing conforms to the law that governs the development of critical thinking,and the adoption of inquiry teaching can promote the development of critical thinking.