The morphological changes of deep-water channels have an important influence on the distributions of channel sand reservoirs,so it is important to explore the morphological change process of deep-water channel for the...The morphological changes of deep-water channels have an important influence on the distributions of channel sand reservoirs,so it is important to explore the morphological change process of deep-water channel for the exploration and development of deep-water oil and gas.Based on a typical sinuous Quaternary channel(Channel I)in the Taranaki Basin,New Zealand,a variety of seismic interpretation techniques were applied to quantitatively characterize the morphological characteristics of the Channel I,and the relationships between the quantitative parameters and the morphological changes of the Channel I,as well as the controlling factors affecting those morphological changes,were discussed.The results are as follows:(1)in the quantitative analysis,six parameters were selected:the channel depth,width,sinuosity,and aspect ratio(width/depth),the channel swing amplitude(λ)and the channel bend frequency(ω);(2)according to the quantitative morphological parameters of the channel(mainly including three parameters such as channel sinuosity,ωandλ),the Channel I was divided into three types:the low-sinuous channel(LSC),the high-sinuous channel(HSC),the moderate-sinuous channel(MSC).U-shaped channel cross-sections developed in the LSC,V-shaped channel cross-sections developed in the HSC,including inclined-V and symmetric-V cross-sections,and dish-shaped channel cross-sections developed in the MSC;(3)the morphological characteristics of the LSC and MSC were related to their widths and depths,while the morphology of the HSC was greatly affected by the channel width,a change in depth did not affect the HSC morphology;(4)the morphological changes of the Channel I were controlled mainly by the slope gradient,the restricted capacity of the channel and the differential in fluid properties.展开更多
In the trend of globalization,digitization,and economic integration,human resources are the core competitiveness of enterprises,and cultivating and developing them is crucial for enhancing competitive advantages.This ...In the trend of globalization,digitization,and economic integration,human resources are the core competitiveness of enterprises,and cultivating and developing them is crucial for enhancing competitive advantages.This article delves into how human resource development drives enterprise innovation,promotes team collaboration,and optimizes performance management.Currently,although many enterprises are beginning to attach importance to human resource development,they still face problems such as insufficient investment,weak targeted training,and insufficient exploration of employee potential.Therefore,it is proposed that in the new situation,enterprises need to strengthen diversified training strategies,use digital tools to improve training efficiency,build a fair performance evaluation system,stimulate employee potential,and promote internal talent mobility.The implementation of these strategies will effectively enhance the efficiency of enterprise human resource management and consolidate market position.展开更多
This paper reviews a strategic scientific proposal to dig and construct three navigable sea lanes linking isolated inland seas and blocked side bays and linking it with the open seas, to facilitate the movement of fre...This paper reviews a strategic scientific proposal to dig and construct three navigable sea lanes linking isolated inland seas and blocked side bays and linking it with the open seas, to facilitate the movement of free trade and international navigation, and to break the captivity of geographically isolated environments, and to give a strategic advantage to some areas and sectors that are neglected politically, socially, economically and environmentally, and to adopt the strategy of establishing a marine channel between the “Caspian Sea” and the “Black Sea” through the “lands belonging to Russia”. On digging a navigational canal at the lowest cost in a plain area within the territory of Russia, with a length of approximately 600 kilometers (616 km), starting from the nearest bay in the Caspian Sea, passing near the city of “Pyatigorsk” to the city of “Sochi” on the Black Sea, while it comes: -The strategy of the waterway and the sea channel between the “Caspian Sea” and the “Arabian Gulf” through the “lands belonging to Iran” by digging and cutting a path in the rocks with a width of 100 meters and a length of about 700 kilometers, and at a time rate of less than 10 years, and this project will liberate all countries in the Caspian Sea, and the study concludes with the strategy of the navigational channel between the “Arabian Gulf” and the “Mediterranean Sea” through the two countries of “Iraq-Syria”, with a length of about 1350 km, and the world will benefit in the security, commercial and political fields.展开更多
According to the measured data after impoundment and operation of the Three Gorges Reservoir,the reservoir sediment deposition and downstream river channel scouring are described briefly and compared with the research...According to the measured data after impoundment and operation of the Three Gorges Reservoir,the reservoir sediment deposition and downstream river channel scouring are described briefly and compared with the research results achieved in the demonstration stage.It is indicated through analysis that the reservoir sediment deposition and downstream river channel scouring during 8-year impoundment and operation are still within the original forecast,so the original forecasting results are feasible.The further observation and comparison should be conducted because the comparison between the observed data and the original forecast is not so sufficient in time and the prototype observation and related research work should be strengthened in the future.展开更多
The Three Gorges Project(TGP)has changed the flow-sediment process in the middle Yangtze River.For navigation purposes,there is an urgent need to study the changes of the river regime over a long-term period and the s...The Three Gorges Project(TGP)has changed the flow-sediment process in the middle Yangtze River.For navigation purposes,there is an urgent need to study the changes of the river regime over a long-term period and the shoal-channel evolution over different seasons since the completion of the TGP.Based on analysis of the measured data and the results of a two-dimensional mathematical model,the changes of the river regime and river bed evolution in the Yaojian reach downstream of the TGP were studied.Results show that a high sediment transport flux helps to keep the main flow in the North Branch,while a low sediment transport flux helps to keep the main flow in the South Branch.Thus,the main branch will not change in the near future because of the low sediment transport load.In this study,the flow-sediment process adjusted by the TGP was restored to the conditions before the TGP,and the river bed evolution under the adjusted and non-adjusted flow-sediment conditions was calculated.After the completion of the TGP,the reservoir storage accelerated the flood recession process and decreased the erosion by 11.9%under the flow-sediment conditions in 2010,and the deposition in the flood season decreased by 56.4%.展开更多
We propose the first statistical theory of language translation based on communication theory. The theory is based on New Testament translations from Greek to Latin and to other 35 modern languages. In a text translat...We propose the first statistical theory of language translation based on communication theory. The theory is based on New Testament translations from Greek to Latin and to other 35 modern languages. In a text translated into another language</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> all linguistic variables do numerically change. To study the chaotic data that emerge, we model any translation as a complex communication channel affected by “noise”, studied according to Communication Theory applied for the first time to this channel. This theory deals with aspects of languages more complex than those currently considered in machine translations. The input language is the “signal”, the output language is a “replica” of the input language, but largely perturbed by noise, indispensable, however, for conveying the meaning of the input language to its readers</span></span></span><span><span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family: Verdana;" cambria="" math","serif";"="">.</span></b></span></span><span style="font-family:""></span><span><span><span style="font-family:""><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">We have defined a noise-to-signal power ratio and found that channels are differently affected by translation noise. Communication channels are also characterized by channel capacity. The translation of novels has more constraints than the New Testament translations. We propose a global readability formula for alphabetical languages, not available for most of them, and conclude with a general theory of language translation which shows that direct and reverse channels are not symmetric. The general theory can also be applied to channels of texts belonging to the same language both to study how texts of the same author may have changed over time, or to compare texts of different authors. In conclusion, a common underlying mathematical structure governing human textual/verbal communication channels seems to emerge. Language does not play the only role in translation;this role is shared with reader’s reading ability and short-term</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">memory capacity. Different versions of New Testament within the same language can even seem, mathematically, to belong to different languages. These conclusions are everlasting because valid also for ancient Roman and Greek readers.展开更多
The East Alligator River drains a 7000 km2 catchment in northern Australia comprised largely of Aboriginal land and has a very low average population density of about 0.15 persons per km2. River reaches were classifie...The East Alligator River drains a 7000 km2 catchment in northern Australia comprised largely of Aboriginal land and has a very low average population density of about 0.15 persons per km2. River reaches were classified according to geomorphic features on both the East Alligator River and its major tributary, Magela Creek, next to which is located the Ranger uranium mine. Sixteen reaches were described for the 241.4 km of the East Alligator River and ten reaches were described for the 118.8 km of Magela Creek. The dominant river types on the East Alligator River were various types of anabranching rivers, sandstone gorges and cuspate tidal meanders. On Magela Creek the dominant river types were wetlands and channel billabongs, island anabranching and sandstone gorges. It is unusual for anabranching rivers and gorges to be so dominant. Current river classification schemes could not accommodate all the various river types and need to be modified so that tidal channels are covered in more detail and so that the classification of anabranching rivers recognises that sand-bed varieties occur in partly confined valley settings.展开更多
The article considers the quantum information channel (QIC) described by the byuon theory (BT)—the theory of the appearance of the world around us: physical space, the world of ultimate particles, living matter etc.,...The article considers the quantum information channel (QIC) described by the byuon theory (BT)—the theory of the appearance of the world around us: physical space, the world of ultimate particles, living matter etc., based on the interaction of non-observable objects (the byuons) nature. The information transporter in the QIC is object 4b (four contact interaction of the four vacuum states of the byuon), carrying information about the information image of the object in physical space—a quantum medium formed by objects 4b. The article proposes a hypothetical model explaining the effects of ultra-high dilutions of chemical and biological substances (UHDS), the search for the physical nature of the action of which is currently underway. UHDS could be the base of the pharmaceutical industry of the future.展开更多
The two renowned water control projects on the Yangtze River—— the Gezhouba Water Control Project and the Three Gorges Water Control Project——are both in Yichang attracting world attention for the region. The Yich...The two renowned water control projects on the Yangtze River—— the Gezhouba Water Control Project and the Three Gorges Water Control Project——are both in Yichang attracting world attention for the region. The Yichang Sub-Council of the China Council for the Promotion of International Trade (CCPIT Yichang Sub-Council) and the Yichang Chamber展开更多
Objective To summarize the development status of direct to patient(DTP)pharmacy and its impact on pharmaceutical enterprises in China and to provide a reference for the pharmaceutical industry.Methods Literature resea...Objective To summarize the development status of direct to patient(DTP)pharmacy and its impact on pharmaceutical enterprises in China and to provide a reference for the pharmaceutical industry.Methods Literature research method was used to research domestic and foreign journals and magazines.Then,all sorts of data were collected to make a comprehensive comparison.Combined with relevant national policies,the current situation and advantages of the DTP pharmacy were analyzed to study its impact on pharmaceutical enterprises.Results and Conclusion Although DTP pharmacies are in the exploratory stage in China,with the advancement of comprehensive medical and health reforms,several national policies have created a good environment for the development of DTP pharmacies.Therefore,DTP pharmacies are accelerating their construction with better market value.As DTP pharmacies gradually become mature,some pharmaceutical enterprises have deepened cooperation with DTP pharmacies to open new channels for drug management.However,from the perspective of some generic drug enterprises,DTP pharmacies have certain adverse effects on them.展开更多
Elucidating the influence of dams on fluvial processes can benefit river protection and basin management. Based on hydrological and topographical data, we analyzed channel evolution in anabranching reaches under chang...Elucidating the influence of dams on fluvial processes can benefit river protection and basin management. Based on hydrological and topographical data, we analyzed channel evolution in anabranching reaches under changing hydrological regimes influenced by the Three Gorges Dam. The main conclusions are as follows: 1) the channels of specific anabranching reaches were defined as flood trend channels or low-flow trend channels according to the distribution of their flow characteristics. The anabranching reaches were classified as T1 or T2. The former is characterized by the correspondence between the flood trend and branch channels, and the latter is characterized by the correspondence between the flood trend and main channels; 2) on the basis of the new classification, the discrepant patterns of channel evolution seen in anabranching reaches were unified into a pattem that showed flood trend channels shrinking and low-flow trend channels expanding; 3) flood abatement and the increased duration of moderate flow discharges are the main factors that affect channel adjustments in anabranching reaches after dam construction; and 4) in the next few decades, the pattern of channel evolution will remain the same as that of the Three Gorges Dam operation. That is, the morphology will fully adapt to a flow with a low coefficient of variation. Our results are of interest in the management of the Yangtze River and other rivers influenced by dams.展开更多
Since the Three Gorges Dam(TGD)was put into operation,the flood water level at an identical discharge rate has not displayed a decreasing trend along the middle reaches of the Yangtze River(MYR).The flow resistance va...Since the Three Gorges Dam(TGD)was put into operation,the flood water level at an identical discharge rate has not displayed a decreasing trend along the middle reaches of the Yangtze River(MYR).The flow resistance variations of the channel and bars in response to the operation of the TGD remain poorly understood,despite the importance of understanding these for water disaster mitigation and water environment regulation.Herein,the impacts of the TGD on the downstream flow resistance of the channel and bars in the MYR were analyzed using systematic surveys of hydrological datasets,cross-sectional profiles,sediment datasets,and remote sensing images,during different periods.Under the actual natural conditions in the MYR,a modified semi-empirical formula,which considered the grain,dune resistance,as well as the topographic features of the riverbed,was proposed to predict the channel resistance.Furthermore,the effect of various dam-control flow and sediment elements on the variation in different flow resistance components,and the corresponding relationships among them were investigated.Results showed a decline in the comprehensive,channel,and bar resistances as the discharge increased,whereas there was a slight increase when reaching the bank-full discharges.Notably,the bar resistance occupied 65%,while the channel resistance,in which dune resistance was much larger than grain resistance,contributed 35%to the comprehensive resistance.In addition,while flow resistance rose over time,there was a decline as the distance from the TGD increased.In conclusion,the increased dune and bar resistances,interpreted by the fluctuated channel longitudinal profile and growing vegetated area on bars,were the dominant factors preventing the flood water level from dropping.展开更多
There is fierce global competition within the banking industry.Therefore,banks endeavor to grow and strive to increase their market share.We analyzed the effect of developing innovative channels of presenting bank ser...There is fierce global competition within the banking industry.Therefore,banks endeavor to grow and strive to increase their market share.We analyzed the effect of developing innovative channels of presenting bank services on banks’market share.The statistical population of this research was Shahr bank’s central headquarter and its branches in Tehran,Iran.We developed questionnaires for gathering the data.The validity and reliability of the scales were tested by EFA,CFA,experts’opinion,and Cronbach’s alpha.We used linear regression to assess the impact of innovative channels,including internet banking,automatic teller machines(ATMs),mobile banking,telephone banking(TB),and point of sales(POS)on banks’market share.The results indicated that some of these channels,including internet banking,POS,and TB,positively affect a bank’s market share.The effect of two other platforms,including mobile banking and ATM development,on banks’market share was rejected.The findings of this study expand our understanding of how bank managers can improve their market share by developing innovative e-banking channels.展开更多
Changes in ectopic discharges from axons in an injured nerve were examined while agents that interact with ion channels were applied to the site of the nerve injury. Tetraethylammonium (TEA) greatly facilitated sponta...Changes in ectopic discharges from axons in an injured nerve were examined while agents that interact with ion channels were applied to the site of the nerve injury. Tetraethylammonium (TEA) greatly facilitated spontaneous ectopic discharges or evoked ectopic firing in previously silent axons.Tetrodotoxin, an Na^+ channel blocker,completely blocked spontaneous discharges.Verapamil, La3^+, and Mn2^+, agents that interact with Ca2^+ channels,blocked spontaneous discharges and depressed the responses evoked by TEA, noradrenaline and high concentration of K^+.Increasing Ca2^+ levels facilitated ectopic discharges and this effect was blocked by La3^+ and Mn2^+. Normal axons (from uninjured nerves) were insensitive to all the effects seen in the axons from the injured nerve.These results suggest that following nerve injury the membrane of the regenerating sprout contains new ion channels, particularly Ca2^+ channels, anti that these channels are responsible for the generation of ectopic discharges.展开更多
基金The National Natural Science Foundation of China under contract Nos 42077410,41872112 and 42002031the Key Scientific Research Projects in University of Henan Province under contract No.18A170007.
文摘The morphological changes of deep-water channels have an important influence on the distributions of channel sand reservoirs,so it is important to explore the morphological change process of deep-water channel for the exploration and development of deep-water oil and gas.Based on a typical sinuous Quaternary channel(Channel I)in the Taranaki Basin,New Zealand,a variety of seismic interpretation techniques were applied to quantitatively characterize the morphological characteristics of the Channel I,and the relationships between the quantitative parameters and the morphological changes of the Channel I,as well as the controlling factors affecting those morphological changes,were discussed.The results are as follows:(1)in the quantitative analysis,six parameters were selected:the channel depth,width,sinuosity,and aspect ratio(width/depth),the channel swing amplitude(λ)and the channel bend frequency(ω);(2)according to the quantitative morphological parameters of the channel(mainly including three parameters such as channel sinuosity,ωandλ),the Channel I was divided into three types:the low-sinuous channel(LSC),the high-sinuous channel(HSC),the moderate-sinuous channel(MSC).U-shaped channel cross-sections developed in the LSC,V-shaped channel cross-sections developed in the HSC,including inclined-V and symmetric-V cross-sections,and dish-shaped channel cross-sections developed in the MSC;(3)the morphological characteristics of the LSC and MSC were related to their widths and depths,while the morphology of the HSC was greatly affected by the channel width,a change in depth did not affect the HSC morphology;(4)the morphological changes of the Channel I were controlled mainly by the slope gradient,the restricted capacity of the channel and the differential in fluid properties.
文摘In the trend of globalization,digitization,and economic integration,human resources are the core competitiveness of enterprises,and cultivating and developing them is crucial for enhancing competitive advantages.This article delves into how human resource development drives enterprise innovation,promotes team collaboration,and optimizes performance management.Currently,although many enterprises are beginning to attach importance to human resource development,they still face problems such as insufficient investment,weak targeted training,and insufficient exploration of employee potential.Therefore,it is proposed that in the new situation,enterprises need to strengthen diversified training strategies,use digital tools to improve training efficiency,build a fair performance evaluation system,stimulate employee potential,and promote internal talent mobility.The implementation of these strategies will effectively enhance the efficiency of enterprise human resource management and consolidate market position.
文摘This paper reviews a strategic scientific proposal to dig and construct three navigable sea lanes linking isolated inland seas and blocked side bays and linking it with the open seas, to facilitate the movement of free trade and international navigation, and to break the captivity of geographically isolated environments, and to give a strategic advantage to some areas and sectors that are neglected politically, socially, economically and environmentally, and to adopt the strategy of establishing a marine channel between the “Caspian Sea” and the “Black Sea” through the “lands belonging to Russia”. On digging a navigational canal at the lowest cost in a plain area within the territory of Russia, with a length of approximately 600 kilometers (616 km), starting from the nearest bay in the Caspian Sea, passing near the city of “Pyatigorsk” to the city of “Sochi” on the Black Sea, while it comes: -The strategy of the waterway and the sea channel between the “Caspian Sea” and the “Arabian Gulf” through the “lands belonging to Iran” by digging and cutting a path in the rocks with a width of 100 meters and a length of about 700 kilometers, and at a time rate of less than 10 years, and this project will liberate all countries in the Caspian Sea, and the study concludes with the strategy of the navigational channel between the “Arabian Gulf” and the “Mediterranean Sea” through the two countries of “Iraq-Syria”, with a length of about 1350 km, and the world will benefit in the security, commercial and political fields.
基金support from the Technology Pillar Program during the"Eleventh Five-year Plan"Period (No.2006BAB05B02No.2006BAB05B03) are acknowledged
文摘According to the measured data after impoundment and operation of the Three Gorges Reservoir,the reservoir sediment deposition and downstream river channel scouring are described briefly and compared with the research results achieved in the demonstration stage.It is indicated through analysis that the reservoir sediment deposition and downstream river channel scouring during 8-year impoundment and operation are still within the original forecast,so the original forecasting results are feasible.The further observation and comparison should be conducted because the comparison between the observed data and the original forecast is not so sufficient in time and the prototype observation and related research work should be strengthened in the future.
基金supported by the National Key Research and Development Program of China(Grants No.2016YFC0402307 and 2016YFC0402103)the National Natural Science Foundation of China(Grant No.51520105014).
文摘The Three Gorges Project(TGP)has changed the flow-sediment process in the middle Yangtze River.For navigation purposes,there is an urgent need to study the changes of the river regime over a long-term period and the shoal-channel evolution over different seasons since the completion of the TGP.Based on analysis of the measured data and the results of a two-dimensional mathematical model,the changes of the river regime and river bed evolution in the Yaojian reach downstream of the TGP were studied.Results show that a high sediment transport flux helps to keep the main flow in the North Branch,while a low sediment transport flux helps to keep the main flow in the South Branch.Thus,the main branch will not change in the near future because of the low sediment transport load.In this study,the flow-sediment process adjusted by the TGP was restored to the conditions before the TGP,and the river bed evolution under the adjusted and non-adjusted flow-sediment conditions was calculated.After the completion of the TGP,the reservoir storage accelerated the flood recession process and decreased the erosion by 11.9%under the flow-sediment conditions in 2010,and the deposition in the flood season decreased by 56.4%.
文摘We propose the first statistical theory of language translation based on communication theory. The theory is based on New Testament translations from Greek to Latin and to other 35 modern languages. In a text translated into another language</span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">,</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> all linguistic variables do numerically change. To study the chaotic data that emerge, we model any translation as a complex communication channel affected by “noise”, studied according to Communication Theory applied for the first time to this channel. This theory deals with aspects of languages more complex than those currently considered in machine translations. The input language is the “signal”, the output language is a “replica” of the input language, but largely perturbed by noise, indispensable, however, for conveying the meaning of the input language to its readers</span></span></span><span><span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family: Verdana;" cambria="" math","serif";"="">.</span></b></span></span><span style="font-family:""></span><span><span><span style="font-family:""><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">We have defined a noise-to-signal power ratio and found that channels are differently affected by translation noise. Communication channels are also characterized by channel capacity. The translation of novels has more constraints than the New Testament translations. We propose a global readability formula for alphabetical languages, not available for most of them, and conclude with a general theory of language translation which shows that direct and reverse channels are not symmetric. The general theory can also be applied to channels of texts belonging to the same language both to study how texts of the same author may have changed over time, or to compare texts of different authors. In conclusion, a common underlying mathematical structure governing human textual/verbal communication channels seems to emerge. Language does not play the only role in translation;this role is shared with reader’s reading ability and short-term</span></span></span></span><span><span><span style="font-family:""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">memory capacity. Different versions of New Testament within the same language can even seem, mathematically, to belong to different languages. These conclusions are everlasting because valid also for ancient Roman and Greek readers.
文摘The East Alligator River drains a 7000 km2 catchment in northern Australia comprised largely of Aboriginal land and has a very low average population density of about 0.15 persons per km2. River reaches were classified according to geomorphic features on both the East Alligator River and its major tributary, Magela Creek, next to which is located the Ranger uranium mine. Sixteen reaches were described for the 241.4 km of the East Alligator River and ten reaches were described for the 118.8 km of Magela Creek. The dominant river types on the East Alligator River were various types of anabranching rivers, sandstone gorges and cuspate tidal meanders. On Magela Creek the dominant river types were wetlands and channel billabongs, island anabranching and sandstone gorges. It is unusual for anabranching rivers and gorges to be so dominant. Current river classification schemes could not accommodate all the various river types and need to be modified so that tidal channels are covered in more detail and so that the classification of anabranching rivers recognises that sand-bed varieties occur in partly confined valley settings.
文摘The article considers the quantum information channel (QIC) described by the byuon theory (BT)—the theory of the appearance of the world around us: physical space, the world of ultimate particles, living matter etc., based on the interaction of non-observable objects (the byuons) nature. The information transporter in the QIC is object 4b (four contact interaction of the four vacuum states of the byuon), carrying information about the information image of the object in physical space—a quantum medium formed by objects 4b. The article proposes a hypothetical model explaining the effects of ultra-high dilutions of chemical and biological substances (UHDS), the search for the physical nature of the action of which is currently underway. UHDS could be the base of the pharmaceutical industry of the future.
文摘The two renowned water control projects on the Yangtze River—— the Gezhouba Water Control Project and the Three Gorges Water Control Project——are both in Yichang attracting world attention for the region. The Yichang Sub-Council of the China Council for the Promotion of International Trade (CCPIT Yichang Sub-Council) and the Yichang Chamber
文摘Objective To summarize the development status of direct to patient(DTP)pharmacy and its impact on pharmaceutical enterprises in China and to provide a reference for the pharmaceutical industry.Methods Literature research method was used to research domestic and foreign journals and magazines.Then,all sorts of data were collected to make a comprehensive comparison.Combined with relevant national policies,the current situation and advantages of the DTP pharmacy were analyzed to study its impact on pharmaceutical enterprises.Results and Conclusion Although DTP pharmacies are in the exploratory stage in China,with the advancement of comprehensive medical and health reforms,several national policies have created a good environment for the development of DTP pharmacies.Therefore,DTP pharmacies are accelerating their construction with better market value.As DTP pharmacies gradually become mature,some pharmaceutical enterprises have deepened cooperation with DTP pharmacies to open new channels for drug management.However,from the perspective of some generic drug enterprises,DTP pharmacies have certain adverse effects on them.
基金This work was supported by the National Key Research and Development Plan (2016YFC0402101), the National Natural Science Foundation of China (Grant No. 51779184), the West Light Foundation of The Chinese Academy of Sciences (XAB2016B06), and the Fundamental Research Funds for the Central Universities (2452017186). The authors are grateful to the editors and anonymous reviewers for their insightful comments and suggestions.
文摘Elucidating the influence of dams on fluvial processes can benefit river protection and basin management. Based on hydrological and topographical data, we analyzed channel evolution in anabranching reaches under changing hydrological regimes influenced by the Three Gorges Dam. The main conclusions are as follows: 1) the channels of specific anabranching reaches were defined as flood trend channels or low-flow trend channels according to the distribution of their flow characteristics. The anabranching reaches were classified as T1 or T2. The former is characterized by the correspondence between the flood trend and branch channels, and the latter is characterized by the correspondence between the flood trend and main channels; 2) on the basis of the new classification, the discrepant patterns of channel evolution seen in anabranching reaches were unified into a pattem that showed flood trend channels shrinking and low-flow trend channels expanding; 3) flood abatement and the increased duration of moderate flow discharges are the main factors that affect channel adjustments in anabranching reaches after dam construction; and 4) in the next few decades, the pattern of channel evolution will remain the same as that of the Three Gorges Dam operation. That is, the morphology will fully adapt to a flow with a low coefficient of variation. Our results are of interest in the management of the Yangtze River and other rivers influenced by dams.
基金National Natural Science Foundation of China(51779185)National Key Research and Development Program of China(2018YFC0407201)。
文摘Since the Three Gorges Dam(TGD)was put into operation,the flood water level at an identical discharge rate has not displayed a decreasing trend along the middle reaches of the Yangtze River(MYR).The flow resistance variations of the channel and bars in response to the operation of the TGD remain poorly understood,despite the importance of understanding these for water disaster mitigation and water environment regulation.Herein,the impacts of the TGD on the downstream flow resistance of the channel and bars in the MYR were analyzed using systematic surveys of hydrological datasets,cross-sectional profiles,sediment datasets,and remote sensing images,during different periods.Under the actual natural conditions in the MYR,a modified semi-empirical formula,which considered the grain,dune resistance,as well as the topographic features of the riverbed,was proposed to predict the channel resistance.Furthermore,the effect of various dam-control flow and sediment elements on the variation in different flow resistance components,and the corresponding relationships among them were investigated.Results showed a decline in the comprehensive,channel,and bar resistances as the discharge increased,whereas there was a slight increase when reaching the bank-full discharges.Notably,the bar resistance occupied 65%,while the channel resistance,in which dune resistance was much larger than grain resistance,contributed 35%to the comprehensive resistance.In addition,while flow resistance rose over time,there was a decline as the distance from the TGD increased.In conclusion,the increased dune and bar resistances,interpreted by the fluctuated channel longitudinal profile and growing vegetated area on bars,were the dominant factors preventing the flood water level from dropping.
文摘There is fierce global competition within the banking industry.Therefore,banks endeavor to grow and strive to increase their market share.We analyzed the effect of developing innovative channels of presenting bank services on banks’market share.The statistical population of this research was Shahr bank’s central headquarter and its branches in Tehran,Iran.We developed questionnaires for gathering the data.The validity and reliability of the scales were tested by EFA,CFA,experts’opinion,and Cronbach’s alpha.We used linear regression to assess the impact of innovative channels,including internet banking,automatic teller machines(ATMs),mobile banking,telephone banking(TB),and point of sales(POS)on banks’market share.The results indicated that some of these channels,including internet banking,POS,and TB,positively affect a bank’s market share.The effect of two other platforms,including mobile banking and ATM development,on banks’market share was rejected.The findings of this study expand our understanding of how bank managers can improve their market share by developing innovative e-banking channels.
基金This work was supported by the National Natural Science Foundation of China the China Medical Board of New York and the Ministry of Public Health of China.
文摘Changes in ectopic discharges from axons in an injured nerve were examined while agents that interact with ion channels were applied to the site of the nerve injury. Tetraethylammonium (TEA) greatly facilitated spontaneous ectopic discharges or evoked ectopic firing in previously silent axons.Tetrodotoxin, an Na^+ channel blocker,completely blocked spontaneous discharges.Verapamil, La3^+, and Mn2^+, agents that interact with Ca2^+ channels,blocked spontaneous discharges and depressed the responses evoked by TEA, noradrenaline and high concentration of K^+.Increasing Ca2^+ levels facilitated ectopic discharges and this effect was blocked by La3^+ and Mn2^+. Normal axons (from uninjured nerves) were insensitive to all the effects seen in the axons from the injured nerve.These results suggest that following nerve injury the membrane of the regenerating sprout contains new ion channels, particularly Ca2^+ channels, anti that these channels are responsible for the generation of ectopic discharges.