Evaluation of the Impact of Refined Quality Control Management Model on the Qualified Rate of Disinfection and Sterilization of Surgical Instruments in the Sterilization Supply Center

Objective:To evaluate the application value of a refined quality control management model for a sterilization supply center.Methods:A retrospective analysis was conducted on the work situation of the sterilization supply center from January 2021 to January 2023.The work situation before January 31,2022,was classified as the control group;a routine quality control management model was implemented,and the work situation after January 31,2022,was classified as the observation group.The quality of medical device management and department satisfaction between the two groups were compared.Results:The timely recovery and supply rate,classification and cleaning pass rate,disinfection pass rate,packaging pass rate,sterilization pass rate,and department satisfaction score in the observation group were all higher than those of the control group(P<0.05).Conclusion:Implementing a refined quality control management model in the sterilization supply center can improve the quality management level of medical devices and department satisfaction and is worthy of promotion.

Radiofrequency ablation combined with transcatheter arterial chemoembolization for recurrent liver cancer

BACKGROUND The recurrence rate of liver cancer after surgery is high.Radiofrequency ablation(RFA)combined with transcatheter arterial chemoembolization(TACE)is an effective treatment for liver cancer;however,its efficacy in recurrent liver cancer remains unclear.AIM To investigate the clinical effect of TACE combined with RFA in the treatment of recurrent liver cancer.METHODS Ninety patients with recurrent liver cancer were divided into 2 groups according to treatment plan:Control(RFA alone);and experimental[TACE combined with RFA(TACE+RFA)].The incidence of increased alanine aminotransferase levels,complications,and other indices were compared between the two groups before and after the procedures.RESULTS One month after the procedures,the short-term efficacy rate and Karnofsky Performance Status scores of the experimental group were significantly higher than those of the control group(P<0.05).Alpha-fetoprotein(AFP)and total bilirubin levels were lower than those in the control group(P<0.05);The overall response rate was 82.22%and 66.67%in the experimental and control groups,respectively;The disease control rate was 93.33%and 82.22%in the experimental and control groups,respectively,the differences are statistically significant(P<0.05).And there were no statistical differences in complications between the two groups(P>0.05).CONCLUSION TACE+RFA was effective for the treatment of recurrent liver cancer and significantly reduced AFP levels and improved various indices of liver function.

Research on Passive Locating Method Using Phase Rate of Change with Variant Posture of the Observer

Technology of passive location has broad prospects in applications. In this paper, the method using the phase rate of change for the single observer passive location is introduced based on existing methods. One can obtain the direction of the target with phase information of two orthogonal interferometers on the observer and the radial distance with the corresponding phase rate of change. Then the target can be located with high speed and precision. A locating approach is given when the flying posture of t...

How to properly evaluate cardiac vagal tone in oncology studies:a state-of-the-art review

Heart rate variability(HRV)analysis provides an assessment of cardiac vagal tone and consequently global cardiac health as well as systemic condition.In systemic diseases such as cancer and during treatments that affect the whole body,like chemotherapy,the vagus nerve activity is low and deregulated.Some studies focus on using HRV to predict mortality in oncology.However,in cancer patients,systemic alterations substantially increase artifacts during HRV measurement,especially atrial ectopic beats.Moreover,HRV may be altered by various factors(duration and time of measurement,breathing,drugs,and other confounding factors)that alter each metric in different ways.The Standard Deviation of all Normal to Normal intervals(SDNN)is the most commonly used metric to evaluate HRV in oncology,but it does not appear to be specific to the cardiac vagal tone.Thus,cardiac vagal activity diagnosis and vital prognosis of cancer patients can be biased.Our review presents the main HRV metrics that can be currently used in oncology studies and their links with vagus nerve and cancer.We present the influence of external factors and the required duration and time of measurement.Considering all these parameters,this review proposes seven key points for an assessment of HRV and cardiac vagal tone in patients with cancer.

Chromosomal Location of the Genes Associated with Photosynthesis of Lophopyrum elongatum (Host) A.Lve in Chinese Spring Background

Researches on the relationship between photosynthesis and wheat yield have equally attracted the attention of both domestic and overseas scholars. No report has existed so far on the study of the effects of exogenous chromosomes on photosynthesis using the substitution series as materials. In this research, Triticum aestivum cv. Chinese Spring-Lophopyrum elongatum （Host） A.Loeve disomic substitution series were used as materials and flag leaves as the measuring position. And the CI-310 Portable Photosynthesis System made by CID Co. in USA was used to measure the net rate of photosynthesis of flag leaves in different developing stages and also to correlate photosynthesis with yield. Results showed that, out of the whole developing stages, at the anthesis stage the line of DS2Ee （2A） had the highest photosynthetic rate, therefore it could be used in improving process of the character of kernel number. The flag leaves of DS4Ee （4A, 4B, 4D） lines demonstrated certain high net photosynthetic rate from heading to grain filling stage, so it is valuable in the researh of promoting the yield index like 1 000-grain weight through improvement of the photosynthetic rate at grain filling stage.

Key Role of Some Specific Occupied Molecular Orbitals of Short Chain n-Alkanes in Their Surface Tension and Reaction Rate Constants with Hydroxyl Radicals: DFT Study

Basing on the DFT calculations we propose the new theoretical model which describes both the surface tension σ of the short chain n-alkanes at their normal boiling points and their reaction rate constants with hydroxyl radicals OH• (at 297 ± 2 K) on the basis of their molecular orbital electronic characteristics. It has been shown that intermolecular dispersion attraction within the surface liquid monolayer of these compounds, as well as their reaction rate constants k with OH• radicals are determined by the energies Eorb of the specific occupied molecular orbitals which are the same in the determination of both the above physico-chemical characteristics of the studied n-alkanes. The received regression equations confirm the theoretically found dependences between the quantities of σ and k and the module |Eorb|. For the compounds under study this fact indicates the key role of their electronic structure particularities in determination of both the physical (surface tension) and the chemical (reaction rate constants) properties.

Unraveling the distribution patterns of near-surface temperature lapse rates in the Northwestern Kunlun Mountains

The near-surface temperature lapse rates for the core area of the Kunlun Mountains remain critically unresolved due to data scarcity.Here,we revealed the spatial and temporal patterns of nearsurface temperature lapse rate in the Kunlun Mountain regions based on both long-term meteorological records(1961-2017)and field surveys measured data(2012-2017).The results showed that(1)The near-surface temperature lapse rates(β;)has spatiotemporal distribution patterns on the Northwestern Kunlun Mountains(NWKM),and in complex terrain areas the complexity of the temperature-elevation relationship cannot be explained by the constant environmental temperature lapse rate(0.65℃/100 m)throughout alone.(2)Theβ;for the daily mean,minimum,and maximum temperature on the north slopes in the Kunlun mountain area are 0.41,0.47,and 0.37℃/100 m and on the Tiznafu River(TR)basin are 0.51,0.47 and 0.53℃/100 m,respectively.(3)The variations ofβ;for daily maximum and minimum temperature of the two regions exhibit similar monthly characteristics,which are lower in the winter and spring months than in other months.A greatest variability ofβ;for the daily mean,minimum,and maximum temperature appears in winter and a light variability ofβ;occurs in spring.The seasonal variability ofβ;for daily maximum temperature is greater than that for daily minimum temperature,and the seasonal variability ofβ;for daily average temperature has the smallest variability.(4)There is no significant trend of change occurred in theβ;of NWKM.(5)The spatial and temporal variations ofβ;for the NWKM are linked to the geographic differences and climate factors.The results of Grey Relational Analysis showed that theβ;distribution is mainly influenced by the wind speed and relative humidity of the NWKM.

Reducing the Error Rate of Drug Delivery in Hospital Pharmacies: From the Angle of Pharmacy Quality Control Circle

Objective To explore the effect of applying pharmacy quality control circle to reduce the error rate of drug delivery in inpatient pharmacy,and to improve the service quality of inpatient pharmacy staff.Methods According to the ten standardized steps of pharmaceutical product management and Gantt chart,fishbone diagram and Plato were used to analyze the causes of drug delivery errors in hospital pharmacies,to find countermeasures and confirm the implementation effect.Results and Conclusion The error rate was reduced from 52% before implementation to 27.8%,and the target achievement rate was 100%.The staff’s understanding and application ability of pharmaceutical product circle was further enhanced.The “Training Standard for Newcomers” has reference value for hospital inpatient pharmacies and it can be promoted continuously.Pharmaceutical quality control circle can improve the quality of pharmacy services in hospitals.

Reducing the Internal Difference Error Rate in Hospital Pharmacies:From the Angle of Quality Control Circle

Objective To improve the management level of pharmacy dispensing center,reduce dispensing errors and promote the safety of drug use.Methods Hospital pharmacies could be managed according to the theory of quality control circle(QCC).Based on the ten steps of QCC,the internal difference error rate in pharmacies could be reduced.Results and Conclusion The error rate of pharmacies was reduced from 2.74‰to 0.57‰,and the goal achievement rate was 108.466.Besides,the progress rate reached 84.82%.The abilities of circle members were improved,and the operation of pharmacy was more standardized.The activity of QCC is helpful to reduce the internal difference error rate,improve the operation level of pharmacy and ensure the safety of drug use.

Hypertension in Clinical Practice: Control Rate in Short Term and Associated Factors in the Cardiology Department of the University Hospital Gabriel Touré(UH-GT) in Bamako (Mali)

Introduction: Hypertension (HTN) is for many decades a worldwide major risk factor for cardiovascular disease.However, hypertension control rates are globally low in the world. Studies on observance have been published in Mali but there is to our knowledge no published data about HTN control rate. We therefore conducted this study to assess the control rate in short term after 3 months management and to look for factors associated with HTN control. Materials and Methods: This study designed as prospective was conducted in the cardiology department of the University Hospital Gabriel Touré (UH-GT) from March 24 to September 24, 2017. All outpatients aged 18 years and more who came for visit and with hypertension as diagnose were involved. All patients have consented to participate in the study. Sociodemographic and data on physical examination including measures for BP, height, weight, waist circumference (WC) and direct costs as reported by the patients were recorded. Patients were asked about medication discontinuation and if yes why and then they were informed about the need to take regularly medication. The concept of chronic disease was explained to them. A formulary served to collect data that were inserted into a Microsoft Access database and analyzed using SPSS version 18. After describing of sociodemographics and continuous variables, crosstabs and finally a logistic regression was performed to look for blood pressure control predictors. Results: There was no statistical difference in sociodemographics between older and newly diagnosed patients. At 3 months globally 40.90% (31.1 for old Patients and 09.8% for newPatients) of the sample were controlled (Figure 1). For old patients, hypertension control rate at inclusion was 12.78% and reached 49.44% at 3 months (Figure 2). After logistic regression only HTN duration was significant predictor with Odd-ratio of 0.365 [0.213 - 0.624] 95% CI and p-value patients as reference). During the study period therapeutic regimen remained unchanged in 73.1% (44.4 for old Patients and 28.7 for newPatients. Calcium channel blocker (CCB), diuretics (DIU) and ACE-inhibitors (ACE-I) were the most prescribed drugs without statistical difference between patients with and without blood pressure under control. Conclusion: Short term hypertension control rate is low and patient follow-up must incorporate information at each visit as well as information through others channels for preventing hypertension. The duration of hypertension was found to be predictor for hypertension control.

Molecular Orbital Nature of Solubility of Shot Chain n-Alkanes in Water and Their Reaction Rate Constants with Nitronium Cations: A DFT Study

The new theoretical models describe both the solubility S of the shot chain n-alkanes in water at 298.15 K, and their reaction rate constants k with nitronium cation NO2+ at 293.15 K on the basis of their molecular orbital characteristics. It is shown that both the quantities S and k are determined by the energies Eorb of the specific virtual (for S) and occupied (for k) molecular orbitals of these n-alkanes. The obtained regression equations confirm the theoretically found dependences of S and k on the absolute value of Eorb. This fact demonstrates that the electronic structure particularities of the studied n-alkanes play a crucial role in both their above-mentioned physicochemical properties.

Investigation of Probability Generating Function in an Interdependent <i>M/M/</i>1:(∞;GD) Queueing Model with Controllable Arrival Rates Using Rouche’s Theorem

Present paper deals a M/M/1:(∞;GD) queueing model with interdependent controllable arrival and service rates where- in customers arrive in the system according to poisson distribution with two different arrivals rates-slower and faster as per controllable arrival policy. Keeping in view the general trend of interdependent arrival and service processes, it is presumed that random variables of arrival and service processes follow a bivariate poisson distribution and the server provides his services under general discipline of service rule in an infinitely large waiting space. In this paper, our central attention is to explore the probability generating functions using Rouche’s theorem in both cases of slower and faster arrival rates of the queueing model taken into consideration;which may be helpful for mathematicians and researchers for establishing significant performance measures of the model. Moreover, for the purpose of high-lighting the application aspect of our investigated result, very recently Maurya [1] has derived successfully the expected busy periods of the server in both cases of slower and faster arrival rates, which have also been presented by the end of this paper.

Impact of Village-based Health Education of Tobacco Control on the Current Smoking Rate in Chinese Rural Areas

The number of smokers in Chinese rural areas is more than 200 million, which is twice that in cities. It is very significant to carry out tobacco control interventions in rural areas. We performed this community intervention study to evaluate the efficacy of village-based health education of tobacco control on the male current smoking rate in rural areas. The population of this study was the males above 15 years old from 6 villages in rural areas. The villages were randomly assigned to intervention group or control group（3 villages in each group）. Self-designed smoking questionnaire was applied. The intervention group received the village-based health education of tobacco control for one year. The primary outcome measurement was the male current smoking rate. In the baseline investigation, completed surveys were returned by 814 male residents from the control group and 831 male residents from the intervention group. The male current smoking rate in the control group and the intervention group was 61.2% and 58.5%, respectively, before intervention. There was no significant difference between these two groups（P〉0.05）. After one-year intervention, the current smoking rate in the intervention group（51.2%） was significantly lower than that in the control group（62.8%）（P〈0.001）. Our study suggested that the village-based health education of tobacco control was effective in lowering the male current smoking rate in rural areas, which could be a suitable and feasible way for tobacco control in the Chinese rural areas.

ON THE ASYMPTOTIC ASSIGNMENT OF THE BOUNDS OF DECREASING RATE FOR A TIME-VARYING LINEAR CONTROL SYSTEM

In the paper the problem on the assignment of the bounds of decreasing rate for a time-varying linear control system is discussed. The sufficient and necessary condition for bounds of decreasing rate of a time-varying linear system to be assigned arbitrarily is presented. It is pointed out that for any given real number m, M, m<M, there exists a linear state feedback with time-varying gain matrix which makes the corresponding closed-loop system possess M and m as its upper bound and lower bound of the decreasing rate respectively. For the purposes of its application to system design the concept of the asymptotic assignment of the bounds of decreasing rate is also proposed. The method dealing with the asymptotic assignment is given too.

Joint Rate Allocation and Buffer Management for Robust Transmission of VBR Video

在这份报纸我们在场在接收装置与播放调整机制在来源集成率分配和缓冲区控制的一个适应录像传播框架。传播率被使用在录像流嵌入以一个精制方法调整传播率的程序钟引用(PCR ) 的一个率分配算法决定。服务者方面也维持多重缓冲区让一些不同重要性层次根据来源缓冲区尺寸，视觉影响，和播放截止时间为控制损失做贸易离开随机的损失。在边界上播放调整机制基于 proportional-integra (PI ) ，控制器在接收装置被采用根据全面损失和接收装置缓冲区占有最大化显示的录像的视觉质量。我们的建议框架的表演在模拟以山峰 signal-to-noise 比率(PSNR ) 被评估，并且模拟结果象译码的框架的更好的质量一样表明平均 PSNR 价值的改进。

Investigation of the kinetic mechanism of the demanganization reaction between carbon-saturated liquid iron and CaF2–CaO–SiO2-based slags

The demanganization reaction kinetics of carbon-saturated liquid iron with an eight-component slag consisting of CaO–SiO2–MgO–FeO–MnO–Al2O3–TiO2–CaF2 was investigated at 1553, 1623, and 1673 K in this study. The rate-controlling step（RCS） for the demanganization reaction with regard to the hot metal pretreatment conditions was studied via kinetics analysis based on the fundamental equation of heterogeneous reaction kinetics. From the temperature dependence of the mass transfer coefficient of a transition-metal oxide（MnO）, the apparent activation energy of the demanganization reaction was estimated to be 189.46 kJ·mol^–1 in the current study, which indicated that the mass transfer of MnO in the molten slag controlled the overall rate of the demanganization reaction. The calculated apparent activation energy was slightly lower than the values reported in the literature for mass transfer in a slag phase. This difference was attributed to an increase in the ＂specific reaction interface＂（SRI） value, either as a result of turbulence at the reaction interface or a decrease of the absolute amount of slag phase during sampling, and to the addition of calcium fluoride to the slag.

Survey of coverage,strategy and cost of hepatitis B vaccination in rural and urban areas of China

AIM In order to understand the coverage, immunization strategy and cost of hepatitis B (HB) vaccination of China in recent years. METHODS A two stage household random sampling method was used in the survey. RESULTS The survey carried out at 112 Disease Surveillance Points (DSPs) of 25 provinces, autonomous regions and municipalities of China in 1996, showed that the coverage rates of HB vaccination among neonates were 96 9% in the urban DSPs and 50 8% in the rural DSPs in 1993-1994, while in students aged 7-9 years, they were 85 8% and 31 5% in 1994, respectively. Up to 1994, 97 5% of the urban DSPs and 73 9% of the rural DSPs on a neonate vaccination against HB program were included in EPI. About 93% of the urban DSPs and 44% of the rural DSPs did HBsAg and HBeAg screening for all or part of pregnant women. The neonates received the regimen of high dose HB vaccine in combination with hepatitis B immune globin (HBIG) if their mothers were HBsAg and/or HBeAg positive in pregnancy, otherwise they received the low dose vaccine (10μg×3). Part of DSPs had a lower neonate coverage due to unreasonable allocation of the vaccines (used for adults not at risk) or higher cost or insufficient supply of the vaccines. It is necessary to evaluate the quality of serological lab test to HBVMs in the maternal prescreening. CONCLUSION Remarkable achievements have been made according to the national planning and policy of HB immunization in China.

Anisodamine accelerates spontaneous passage of single symptomatic bile duct stones ≤ 10 mm

AIM:To investigate the rate of spontaneous passage of single and symptomatic common bile duct(CBD)stones≤10 mm in diameter in 4 wk with or without a2-wk course of anisodamine.METHODS:A multicenter,randomized,placebocontrolled trial was undertaken.A total of 197 patients who met the inclusion criteria were enrolled.Ninetyseven patients were assigned randomly to the control group and the other 100 to the anisodamine group.The anisodamine group received intravenous infusions of anisodamine(10 mg every 8 h)for 2 wk.The control group received the same volume of 0.9%isotonic saline for 2 wk.Patients underwent imaging studies and liver-function tests every week for 4 wk.The rate of spontaneous passage of CBD stones was analyzed.RESULTS:The rate of spontaneous passage of CBD stones was significantly higher in the anisodamine group than that in the control group(47.0%vs 22.7%).Most(87.2%,41/47)stone passages in the anisodamine group occurred in the first 2 wk,and passages in the control group occurred at a comparable rate each week.Factors significantly increasing the possibility of spontaneous passage by univariate logistic regression analyses were stone diameter(<5 mm vs≥5 mm and≤10 mm)and anisodamine therapy.Multivariate logistic regression analyses revealed that these two factors were significantly associated with spontaneous passage.CONCLUSION:Two weeks of anisodamine administration can safely accelerate spontaneous passage of single and symptomatic CBD stones≤10 mm in diameter,especially for stones<5 mm.

The Thermal History of the Huangmeijian Granite Intrusion in Anhui and Its Relation to Mineralization: Isotopic Evidence

Whole-rock Rb-Sr, zircon U-Pb and hornblende, biotite and K-feldspar K-Ar ages areused to reconstruct the cooling history of the Huangmeijian intrusion in the Anqing-Lujiangquartz-syenite belt in Anhui. Oxygen isotope geothermometry of mineral pairs demonstrates thatdiffusion is a dominant factor controlling the closure of isotopic systems. Assuming the coolingof the intrusion is synchronous with a dicrease in local geothermal gradients, an emplacementdepth of about 8 km and the magma crystallization temperature of 800±50℃ are estimated. TheHuangmeijian intrusion experienced a rapid cooling process and uplifted after its emplacementand crystallization at 133 Ma B.P. with a cooling rate of 34.5℃/Ma and an uplifting rate of 0.35mm/a. The intrusion was rising until it rested at a depth of 3km at a temperature of 300±50℃about 14 Ma later. Then the intrusion was in slow cooling and uplifting with a cooling rate of4.4℃/Ma and an uplifting rate of 0.04 mm/a. U-Pb dating of pitchblende is done for the hydrothermal uranium deposit formed in thecontact zone of the Huangmeijian intrusion. The result shows that the mineralization age is closeto the closing time of the K-Ar system in biotite. The fluid inclusion thermometry indicates thatthe mineralization temperature is in agreement with the closure temperature of the biotite K-Arsystem. This suggests a close relationship between the slow cooling of the intrusion and thehydrothermal uranium mineralization process.

Mathematical model and magnetic-control mechanism of the stability of rotating spray transfer

To realize stable rotating spray transfer in the region of high constant current is the key of realizing high deposition rate MAG welding process without helium in shielding gas and extending the welding current range of traditional MAG welding process. In this paper, the magnetic control mechanism of the rotating spray transfer is stated and mathematical model is given. Theoretic basis is established, which implements high deposition rate MAG welding process with magnetic control instead of helium in shielding gas.