AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sam...AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD(aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroenterology service.Sixty-four participants met diagnostic criteria for Crohn's disease,while eightythree patients had ulcerative colitis.Socio-demographic data(education,age,race,gender,gross monthly income and marital status),disease-related variables(illness activity,relapse rate in past 2 years,history of surgery and time since diagnosis),sense of coherence(Antonovsky's SOC scale),psychological distress symptoms(Hospital Anxiety and Depression Scale) and health-related quality of life(HRQo L; WHOQOLBref) were assessed.Hierarchical multiple regression analyses were performed to identify factors that are independently associated with psychological distress and HRQo L in patients with IBD and to provide indications for possible moderating or mediating effects.In addition,formal moderation and mediation analyses(Sobel tests) were performed to confirm potential moderators/mediators of the relationship between SOC,psychological distress symptoms and HRQoL.RESULTS:Lower SOC scores(std beta=-0.504; P < 0.001),female gender(std beta = 0.176; P = 0.021) and White race(std beta = 0.164; P = 0.033) were independently associated with higher levels of depressive symptoms,while lower levels of SOC(std beta =-0.438; P < 0.001) and higher relapse rate(std beta = 0.161; P = 0.033) were independently associated with more severe anxiety symptoms.A significant interaction between time since diagnosis and SOC was found with regard to the severity of depressive or anxiety symptoms,as the interaction term(time since diagnosis X SOC) had beta coefficients of-0.191(P = 0.009) and-0.172(P = 0.026),respectively.Lower levels of anxiety symptoms(std beta =-0.369; P < 0.001),higher levels of SOC(std beta = 0.231; P = 0.016) and non-White race(std beta =-0.229; P = 0.006),i.e.,mixed-race,which represented the reference category,were independently associated with higher levels of overall HRQoL.Anxiety symptoms were the most potent independent correlate of most aspects of HRQoL.In addition,anxiety mediated the association between SOC and satisfaction with health,as well as its relationship with physical,mental,and social relations HRQo L.Depressive symptoms also mediated the association between SOC and mental HRQoL.CONCLUSION:Our data indicated that SOC is an important construct,as it influences psychological distress and has significant albeit indirect effects on several HRQoL domains in IBD.展开更多
Metabolic syndrome has recently become a concern in Japan. It is commonly believed that lifestyle quality must be improved and main- tained for optimum health. A cross-sectional survey of middle-aged workers was perfo...Metabolic syndrome has recently become a concern in Japan. It is commonly believed that lifestyle quality must be improved and main- tained for optimum health. A cross-sectional survey of middle-aged workers was performed to examine the relationship between a sense of coherence (SOC) and health status. The study further aimed to determine the quality of life necessary to maintain physical and psychologi- cal health. An anonymous online survey was conducted with a panel of respondents regis- tered with an Internet research service. The survey items addressed SOC and awareness of lifestyle habits, specifically lifestyle factors of self-rated health, level of satisfaction, and level of stress. Responses were obtained from 412 women and 206 men. The approximately equal high and low SOC results indicated that self- rated health and level of satisfaction were signi- ficantly higher in both sexes with a high SOC, and such participants also experienced signifi- cantly lower levels of daily stress. With regard to the association between lifestyle factors and health, women with a high SOC tended to have shorter commutes, and a higher percentage ate breakfast daily compared with women with a low SOC. Men with a high SOC worked significantly longer hours, and a higher percentage were ei- ther married or resided with family. No sex dif- ferences in SOC were observed for health be- havior in daily life, and 50% of both women and men reported positive health behavior. Health behavior differed, however, according to SOC and sex. These findings suggest that health pre- servation in daily life of middle-aged worker’s women is possible through sustaining and en- hancing展开更多
文摘AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD(aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroenterology service.Sixty-four participants met diagnostic criteria for Crohn's disease,while eightythree patients had ulcerative colitis.Socio-demographic data(education,age,race,gender,gross monthly income and marital status),disease-related variables(illness activity,relapse rate in past 2 years,history of surgery and time since diagnosis),sense of coherence(Antonovsky's SOC scale),psychological distress symptoms(Hospital Anxiety and Depression Scale) and health-related quality of life(HRQo L; WHOQOLBref) were assessed.Hierarchical multiple regression analyses were performed to identify factors that are independently associated with psychological distress and HRQo L in patients with IBD and to provide indications for possible moderating or mediating effects.In addition,formal moderation and mediation analyses(Sobel tests) were performed to confirm potential moderators/mediators of the relationship between SOC,psychological distress symptoms and HRQoL.RESULTS:Lower SOC scores(std beta=-0.504; P < 0.001),female gender(std beta = 0.176; P = 0.021) and White race(std beta = 0.164; P = 0.033) were independently associated with higher levels of depressive symptoms,while lower levels of SOC(std beta =-0.438; P < 0.001) and higher relapse rate(std beta = 0.161; P = 0.033) were independently associated with more severe anxiety symptoms.A significant interaction between time since diagnosis and SOC was found with regard to the severity of depressive or anxiety symptoms,as the interaction term(time since diagnosis X SOC) had beta coefficients of-0.191(P = 0.009) and-0.172(P = 0.026),respectively.Lower levels of anxiety symptoms(std beta =-0.369; P < 0.001),higher levels of SOC(std beta = 0.231; P = 0.016) and non-White race(std beta =-0.229; P = 0.006),i.e.,mixed-race,which represented the reference category,were independently associated with higher levels of overall HRQoL.Anxiety symptoms were the most potent independent correlate of most aspects of HRQoL.In addition,anxiety mediated the association between SOC and satisfaction with health,as well as its relationship with physical,mental,and social relations HRQo L.Depressive symptoms also mediated the association between SOC and mental HRQoL.CONCLUSION:Our data indicated that SOC is an important construct,as it influences psychological distress and has significant albeit indirect effects on several HRQoL domains in IBD.
文摘Metabolic syndrome has recently become a concern in Japan. It is commonly believed that lifestyle quality must be improved and main- tained for optimum health. A cross-sectional survey of middle-aged workers was performed to examine the relationship between a sense of coherence (SOC) and health status. The study further aimed to determine the quality of life necessary to maintain physical and psychologi- cal health. An anonymous online survey was conducted with a panel of respondents regis- tered with an Internet research service. The survey items addressed SOC and awareness of lifestyle habits, specifically lifestyle factors of self-rated health, level of satisfaction, and level of stress. Responses were obtained from 412 women and 206 men. The approximately equal high and low SOC results indicated that self- rated health and level of satisfaction were signi- ficantly higher in both sexes with a high SOC, and such participants also experienced signifi- cantly lower levels of daily stress. With regard to the association between lifestyle factors and health, women with a high SOC tended to have shorter commutes, and a higher percentage ate breakfast daily compared with women with a low SOC. Men with a high SOC worked significantly longer hours, and a higher percentage were ei- ther married or resided with family. No sex dif- ferences in SOC were observed for health be- havior in daily life, and 50% of both women and men reported positive health behavior. Health behavior differed, however, according to SOC and sex. These findings suggest that health pre- servation in daily life of middle-aged worker’s women is possible through sustaining and en- hancing
