“Magnetic window”is considered as an effective method to solve the communication blackout issue.COMSOL software package based on the finite element method is utilized to simulate the propagation of right-handed circ...“Magnetic window”is considered as an effective method to solve the communication blackout issue.COMSOL software package based on the finite element method is utilized to simulate the propagation of right-handed circularly polarized wave in the magnetized plasma sheath.We assume a double Gaussian model of electron density and an exponential attenuation model of magnetic field.The propagation characteristics of right-handed circularly polarized wave are analyzed by the observation of the reflected,transmitted and loss coefficient.The numerical results show that the propagation of right-handed circularly polarized wave in the magnetized plasma sheath varies for different incident angles,collision frequencies,non-uniform magnetic fields and non-uniform plasma densities.We notice that reducing the wave frequency can meet the propagation conditions of whistle mode in the weak magnetized plasma sheath.And the transmittance of whistle mode is less affected by the variation of the electron density and the collision frequency.It can be used as a communication window.展开更多
BACKGROUND Epithelioid malignant peripheral nerve sheath tumor(EMPNST)of the bladder is a rare entity with devastating features.These tumors are thought to originate from malignant transformation of pre-existing schwa...BACKGROUND Epithelioid malignant peripheral nerve sheath tumor(EMPNST)of the bladder is a rare entity with devastating features.These tumors are thought to originate from malignant transformation of pre-existing schwannomas of pelvic autonomic nerve plexuses,and unlike the conventional malignant peripheral nerve sheath tumor(MPNST),are not associated with neurofibromatosis.The tumor has dis-tinctive morphological,immunohistochemical and molecular features.Addi-tionally,it tends to be more aggressive and have a higher mortality.This is the first case that presents with a synchronous urothelial carcinoma of the bladder and the epithelioid variant of MPNST in the literature.It’s also the second re-ported case of EMPNST originating from the bladder wall.CASE SUMMARY In this case report,we present the detailed clinical course of a 71-year-old patient with EMPNST of the bladder alongside a literature review.CONCLUSION During the management of EMPNST cases,offering aggressive treatment moda-lities to the patient,such as radical cystectomy,is appropriate for the best chance to contain the disease,regardless of the tumor stage and the extent of local disease at initial diagnosis.展开更多
When the contacts of a medium-voltage DC air circuit breaker(DCCB) are separated, the energy distribution of the arc is determined by the formation process of the near-electrode sheath. Therefore, the voltage drop thr...When the contacts of a medium-voltage DC air circuit breaker(DCCB) are separated, the energy distribution of the arc is determined by the formation process of the near-electrode sheath. Therefore, the voltage drop through the near-electrode sheath is an important means to build up the arc voltage, which directly determines the current-limiting performance of the DCCB. A numerical model to describe the near-electrode sheath formation process can provide insight into the physical mechanism of the arc formation, and thus provide a method for arc energy regulation. In this work, we establish a two-dimensional axisymmetric time-varying model of a medium-voltage DCCB arc when interrupted by high current based on a fluid-chemical model involving 16 kinds of species and 46 collision reactions. The transient distributions of electron number density, positive and negative ion number density, net space charge density, axial electric field, axial potential between electrodes, and near-cathode sheath are obtained from the numerical model. The computational results show that the electron density in the arc column increases, then decreases, and then stabilizes during the near-cathode sheath formation process, and the arc column's diameter gradually becomes wider. The 11.14 V–12.33 V drops along the17 μm space charge layer away from the cathode(65.5 k V/m–72.5 k V/m) when the current varies from 20 k A–80 k A.The homogeneous external magnetic field has little effect on the distribution of particles in the near-cathode sheath core,but the electron number density at the near-cathode sheath periphery can increase as the magnetic field increases and the homogeneous external magnetic field will lead to arc diffusion. The validity of the numerical model can be proven by comparison with the experiment.展开更多
With the popularization of central venous catheterization in recent years,the problems arising from intravenous therapy have gradually increased.Fibrin sheath is the complication with the highest incidence rate in cen...With the popularization of central venous catheterization in recent years,the problems arising from intravenous therapy have gradually increased.Fibrin sheath is the complication with the highest incidence rate in central venous catheterization,which has always been a major problem in intravenous therapy.So the prevention and treatment of fibrin sheath has become a hot spot of research in recent years.Hence,this paper summarizes the research on fibrin sheath in recent years.展开更多
During spacecraft re-entry,the challenge of measuring plasma sheath parameters directly contributes to difficulties in addressing communication blackout.In this work,we have discovered a phenomenon of multiple peaks i...During spacecraft re-entry,the challenge of measuring plasma sheath parameters directly contributes to difficulties in addressing communication blackout.In this work,we have discovered a phenomenon of multiple peaks in reflection data caused by the inhomogeneous plasma.Simulation results show that the multi-peak points fade away as the characteristic frequency is approached,resembling a series of gradually decreasing peaks.The positions and quantities of these points are positively correlated with electron density,yet they show no relation to collision frequency.This phenomenon is of significant reference value for future studies on the spatial distribution of plasmas,particularly for using microwave reflection signals in diagnosing the plasma sheath.展开更多
Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system.Recent evidence has challenged the classical view of the functio...Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system.Recent evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to axons.Despite the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is lacking.We delve into early 20th-century studies by Robertson and Río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature oligodendrocytes.Indeed,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination preferences.Furthermore,modern molecular investigations,employing techniques such as single cell/nucleus RNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system region.Age and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric disorders.Nevertheless,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined investigations.Future studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte heterogeneity.Such research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,hold promise for the development of therapeutic interventions targeting varied central nervous system pathology.展开更多
Generally,the so-called expansion agent is very effective in eliminating all the micro-annuli that exist between the casing and the cement sheath or between the cement sheath and the formation.However,this approach ca...Generally,the so-called expansion agent is very effective in eliminating all the micro-annuli that exist between the casing and the cement sheath or between the cement sheath and the formation.However,this approach can detrimentally affect the sealing ability of cement sheath if the expansion agent is used in an unreasonable way.For these reasons,in the present work,numerical simulations have been conducted to analyze the effect of elasticity modulus of cement sheath,the elasticity modulus of formation,the expansion rate of cement,the geo-stress on the micro-annulus caused by cement expansion,and the cement sheath expansion on the integrity of cement sheath and formation.The micro-annulus between the casing and the cement sheath has been found to decrease according to the ratio between the elasticity modulus of formation and the elasticity modulus of cement sheath.A positive correlation has been observed between the micro-annulus and the cement expansion ratio.The microannulus decreases as the geo-stress increases,but the effect of the geo-stress on the micro-annulus is much smaller.In conclusion,the expansion agent is suitable for the formation in which the elasticity modulus is higher than the cement sheath.展开更多
To understand the characteristics of the plasma sheath within small tubes,a 2D numerical model of He discharge within dielectric tubes is developed.During plasma propagation for a tube diameter of 0.05 mm,the sheath t...To understand the characteristics of the plasma sheath within small tubes,a 2D numerical model of He discharge within dielectric tubes is developed.During plasma propagation for a tube diameter of 0.05 mm,the sheath thickness in the plasma head is almost equal to the tube radius.It decreases rapidly to several micrometers at an axial distance of 0.05 mm behind the plasma head,and then slightly increases and saturates at the axial position far behind the plasma head.A plasma-gas sheath surrounding the central plasma column is observed for a tube diameter equal to or greater than 0.8 mm.It is replaced by a plasma-wall sheath for smaller tubes.With the decrease in the tube diameter,the sheath thickness far behind the plasma head decreases while the ion flux increases significantly.However,when O_(2)gas with a proportion of 2%is added,both the sheath thickness and ion flux decrease.展开更多
One of the main obstacles hindering the exploitation of high-temperature and high-pressure oil and gas is the sealing integrity of the cement sheath.Analyzing the microstructure of the cement sheath is therefore an im...One of the main obstacles hindering the exploitation of high-temperature and high-pressure oil and gas is the sealing integrity of the cement sheath.Analyzing the microstructure of the cement sheath is therefore an important task.In this study,the microstructure of the cement sheath is determined using a CT scanner under different temperature and pressure conditions.The results suggest that the major cause of micro-cracks in the cement is the increase in the casing pressure.When the micro-cracks accumulate to a certain extent,the overall structure of the cement sheath is weakened,resulting in gas channeling,which poses a direct threat to the safe production of oil and gas.A change in the casing temperature has a limited effect on the microstructure of the cement sheath.展开更多
OsPLS4 encodes aβ-ketoacyl carrier protein reductase(KAR).The role of OsPLS4 in rice sheath blight(Rhizoctonia solani)remains unclear.Our preliminary studies showed that premature leaf senescence mutants(pls4)were hi...OsPLS4 encodes aβ-ketoacyl carrier protein reductase(KAR).The role of OsPLS4 in rice sheath blight(Rhizoctonia solani)remains unclear.Our preliminary studies showed that premature leaf senescence mutants(pls4)were highly susceptive to sheath blight in the early stage of rice development.To explore the role of this gene in the development of rice sheath blight,the transcriptome profiles of the rice pls4 mutant and wild type were compared by RNA-seq.The results revealed 2,569 differentially expressed genes(DEGs).The down-regulated genes were significantly enriched in the defense response-related biological processes.These down-regulated genes included the chitinase genes and WRKY genes,which were significantly changed in pls4 mutants.Furthermore,467 genes induced significant alternative splicing(AS)events.Among them,intron retention(IR)affected gene expression levels and functions of the vitamin B6(VB6)metabolism pathway related to sheath blight.This result suggests that IR plays an important role in the sheath blight resistance of mutant pls4.Together,these results indicate that pls4 could be involved in the biological process of sheath blight via DEGs and the fine-tuning of IR.The present study provides a molecular basis for further investigation of the resistance of rice to sheath blight.展开更多
BACKGROUND Malignant peripheral nerve sheath tumor(MPNST)is a rare and aggressive soft tissue sarcoma that poses a major diagnostic and therapeutic challenge.CASE SUMMARY We retrospectively reviewed patients with head...BACKGROUND Malignant peripheral nerve sheath tumor(MPNST)is a rare and aggressive soft tissue sarcoma that poses a major diagnostic and therapeutic challenge.CASE SUMMARY We retrospectively reviewed patients with head and neck MPNSTs treated in our hospital from 2000 to 2021.The clinical features,pathological manifestations,treatments,and prognoses were summarized.We also reviewed the literature,focusing on MPNST in the mandible and maxilla.The study population consisted of five women and five men aged 22–75 years(mean age,49 years).Of the 10 patients,7 were initial cases and 3 were recurrent cases.All lesions were sporadic.The most common site was the mandible.The most frequently encountered symptoms were a progressive mass and local swelling.Complete or partial loss of trimethylation at lysine 27 of histone H3(H3K27me3)was evident on staining in four of nine cases(one case was excluded due to lack of tissue for evaluation of loss of H3K27me3).The 2-and 5-year disease-specific survival rates were 86%a nd 43%,respectively.The average survival time was 64 mo.CONCLUSION MPNST is a highly malignant tumor with a poor prognosis,prone to a high risk of recurrence and distant metastasis.Complete surgical resection is the main treatment.展开更多
In the plasma sheath, there is a significant gradient in ion velocity, resulting in strong stress on ions treated as a fluid. This aspect has often been neglected in previous sheath studies. This study is based on the...In the plasma sheath, there is a significant gradient in ion velocity, resulting in strong stress on ions treated as a fluid. This aspect has often been neglected in previous sheath studies. This study is based on the Braginskii plasma transport theory and establishes a 1D3V sheath fluid model that takes into account the ion stress effect. Under the assumption that ions undergo both electric and diamagnetic drift in the presheath region, self-consistent boundary conditions,including the ion Bohm velocity, are derived based on the property of the Sagdeev pseudopotential.Furthermore, assuming that the electron velocity at the wall follows a truncated Maxwell distribution, the wall floating potential is calculated, leading to a more accurate sheath thickness estimation. The results show that ion stress significantly reduces the sheath thickness, enhances ion Bohm velocity, wall floating potential, and ion flux at the wall. It hinders the acceleration of ions within the sheath, leading to notable alterations in the particle density profiles within the sheath. Further research indicates that in ion stress, bulk viscous stress has the greatest impact on sheath properties.展开更多
Objective:To evaluate the effect of ureteral access sheath(UAS)use and calibration change on stone-free rate and complications of retrograde intrarenal surgery(RIRS).Methods:Data from 568 patients undergoing RIRS for ...Objective:To evaluate the effect of ureteral access sheath(UAS)use and calibration change on stone-free rate and complications of retrograde intrarenal surgery(RIRS).Methods:Data from 568 patients undergoing RIRS for kidney or upper ureteral stones were retrospectively included.Firstly,patients were compared after 1:1 propensity score matching,according to UAS usage during RIRS(UAS used[+]87 and UAS non-used[−]87 patients).Then all UAS+patients(n=481)were subdivided according to UAS calibration:9.5-11.5 Fr,10-12 Fr,11-13 Fr,and 13-15 Fr.Primary outcomes of the study were the success and complications of RIRS.Results:Stone-free rate of UAS+patients(86.2%)was significantly higher than UAS−patients(70.1%)after propensity score matching(p=0.01).Stone-free rate increased with higher caliber UAS(9.5-11.5 Fr:66.7%;10-12 Fr:87.0%;11-13 Fr:90.6%;13-15 Fr:100%;p<0.001).Postoperative complications of UAS+patients(11.5%)were significantly lower than UAS−patients(27.6%)(p=0.01).Complications(8.7%)with 9.5-11.5 Fr UAS was lower than thicker UAS(17.2%)but was not statistically significant(p=0.09).UAS usage was an independent factor predicting stone-free status or peri-and post-operative complications(odds ratio[OR]3.654,95%confidence interval[CI]1.314-10.162;OR 4.443,95%CI 1.350-14.552;OR 4.107,95%CI 1.366-12.344,respectively).Conclusion:Use of UAS in RIRS may increase stone-free rates,which also increase with higher caliber UAS.UAS usage may reduce complications;however,complications seemingly increase with higher UAS calibration.展开更多
BACKGROUND:As advocated in advanced trauma life support and prehospital trauma life support protocols,cervical immobilization is applied until cervical spine injury is excluded.This study aimed to show the difference ...BACKGROUND:As advocated in advanced trauma life support and prehospital trauma life support protocols,cervical immobilization is applied until cervical spine injury is excluded.This study aimed to show the difference in optic nerve sheath diameter(ONSD)between patients with and without a cervical collar using computed tomography(CT).METHODS:This was a single-center,retrospective study examining trauma patients who presented to the emergency department between January 1,2021,and December 31,2021.The ONSD on brain CT of the trauma patients was measured and analyzed to determine whether there was a difference between the ONSD with and without the cervical collar.RESULTS:The study population consisted of 169 patients.On CT imaging of patients with(n=66)and without(n=103)cervical collars,the mean ONSD in the axial plane were 5.43±0.50 mm and 5.04±0.46 mm respectively for the right eye and 5.50±0.52 mm and 5.11±0.46 mm respectively for the left eye.The results revealed an association between the presence of a cervical collar and the mean ONSD,which was statistically significant(P<0.001)for both the right and left eyes.CONCLUSION:A cervical collar may be associated with increased ONSD.The effect of this increase in the ONSD on clinical outcomes needs to be investigated,and the actual need for cervical collar in the emergency department should be evaluated on a case-by-case basis.展开更多
AIM:To investigate the symmetry of upper eyelid in patients with unilateral mild and moderate blepharoptosis who underwent unilateral minimally invasive combined fascia sheath(CFS)suspension.METHODS:A retrospective st...AIM:To investigate the symmetry of upper eyelid in patients with unilateral mild and moderate blepharoptosis who underwent unilateral minimally invasive combined fascia sheath(CFS)suspension.METHODS:A retrospective study of patients who underwent unilateral minimally invasive CFS suspension surgery between January 2018 and December 2021.Inclusion criteria included unilateral mild and moderate ptosis,good levator muscle function(>9 mm)and follow-up of at least 6mo.Pre-and post-operative symmetry was graded subjectively for marginal reflex distance 1(MRD1),tarsal platform show(TPS)and eyebrow fat span(BFS).A t-test was used to evaluate MRD1,TPS and BFS asymmetry by calculating delta values.The Bézier curve tool of the Image J software was used to extract the upper eyelid contours,where the symmetry was measured by the percentage of overlapping curvatures(POC).RESULTS:Totally 105 patients(105 eyelids)were included(mild group,n=84;moderate group,n=21).Postoperatively,all patients increased MRD1 and decreased TPS in the ptotic eye while maintaining unchanged BFS.The asymmetric delta value for MRD1 was measured to be 1.48±0.86 preoperatively,and it decreased to 0.58±0.67 postoperatively in all cases(P=0.0004).In patients with mild ptosis,the asymmetry value of TPS fell significantly from 1.15±0.62 to 0.68±0.38(P=0.0187).The symmetry of the upper eyelid contour increased in all subgroups of patients,with a POC of 59.39%±13.45%preoperatively and POC of 78.29%±13.80%postoperatively.CONCLUSION:Minimally invasive CFS suspension is proved to be an effective means of improving the symmetry of unilateral ptosis in terms of MRD1(all subgroups),POC(all subgroups)and TPS(only mild group),whereas BFS is unaffected.展开更多
Equisetum(Equisetaceae)has long been a focus of attention for botanists and palaeontologists because,given its extensive and well-documented fossil record,it is considered the oldest extant vascular plant and a key el...Equisetum(Equisetaceae)has long been a focus of attention for botanists and palaeontologists because,given its extensive and well-documented fossil record,it is considered the oldest extant vascular plant and a key element in understanding vascular plant evolution.However,to date,no authentic fossil evidence of Equisetum has been found from the Indian Cenozoic.Here,we describe a new fossil species,namely,E.siwalikum sp.nov.,recovered from the middle Siwalik(Late Miocene)sediments of Himachal Pradesh,western Himalaya.We identified fossil specimens based on morphological and epidermal characters.In addition,X-Ray diffraction(XRD)analysis was used to determine the mineral composition of compressed stems of Equisetum.The close affinity of our recovered Siwalik fossils to Equisetum is supported by the presence of both macromorphological and epidermal characters.Because Equisetum generally grows in wet conditions around water reservoirs,our findings indicate that the fossil locality was humid and surrounded by swamp and lowland regions during deposition.Ample fossil evidence indicates that this sphenopsid once existed in the western Himalaya during the Siwalik period.However,at present Equisetum is confined to a particular area of our fossil locality,probably a consequence of severe environmental changes coupled with competition from opportunistic angiosperms.Our discovery of Equisetum fossils in appreciable numbers from the Siwalik sediments of the Himachal Himalayas is unique and constitutes the first reliable recognition of Equisetum from the Indian Cenozoic.展开更多
The major QTL-qSB-9^Tq conferring partial resistance to rice (Oryza sativa L.) sheath blight (Rhizoctonia solani Kvhn) has been verified on chromosome 9 of the indica rice cultivar, Teqing. In this study, the pros...The major QTL-qSB-9^Tq conferring partial resistance to rice (Oryza sativa L.) sheath blight (Rhizoctonia solani Kvhn) has been verified on chromosome 9 of the indica rice cultivar, Teqing. In this study, the prospect of this QTL utilized in molecular breeding program of japonica rice for sheath blight resistance was investigated. Most of the japonica rice cultivars showed lower level of sheath blight resistance than the indica rice cultivars. At the corresponding site of qSB-9^Tq, nine typical japonica rice cultivars from different ecological regions or countries proved to possess the susceptible allele(s). Introgression of qSB-9^Tq into these cultivars enhanced their resistance level by decreasing sheath blight score of 1.0 (0.5-1.3), which indicated that qSB-9^Tq had a large potential in strengthening the resistance of japonica rice to sheath blight. The use of the three molecular markers, which were polymorphic between Teqing and many japonica rice cultivars, promotes the application of qSB-9^Tq in a concrete molecular breeding program.展开更多
Sheath blight of rice, caused by Rhizoctonia solani AG 1. 1a, has become the most important disease and caused serious yield losses in some major rice-growing regions in China in recent years. In the present study, fi...Sheath blight of rice, caused by Rhizoctonia solani AG 1. 1a, has become the most important disease and caused serious yield losses in some major rice-growing regions in China in recent years. In the present study, field plot experiment was conducted to examine the relationships between disease intensity and inoculum density (ID), the seasonal disease epidemic dynamics, and yield reductions due to disease damages. Results from the experiment demonstrated that the areas under progress curves of disease severity and those of percent rice tillers diseased were positively and closely related to the relative initial ID of the pathogen. The inoculum density-disease (IDD) relationships were simulated and the impractical linear models were obtained. Both logistic and Gompertz functions could be used to simulate the disease progress dynamics in time, but the progress curves of the disease severity were modeled better by the Gompertz than by logistic function. However, the Richards function was found to be the best in simulating the disease progress curves when a most appropriate value was chosen for the shape parameter m by using the computer software Epitimulator. Sheath blight infection decreased rice yield very significantly and a yield reduction of 40% was recorded in rice crop with the highest inoculum density. Rice yield was linearly and negatively correlated with the disease severity and the percent tillers affected. The simulated models for all these relationships were computed through executing Epitimulator software and were presented in this paper.展开更多
AIM:To investigate clinical features of optic nerve sheath meningioma(ONSM) that was misdiagnosed,and to find methods to reduce the misdiagnoses.METHODS:Retrospective series study.Twenty-five misdisgnosed patients...AIM:To investigate clinical features of optic nerve sheath meningioma(ONSM) that was misdiagnosed,and to find methods to reduce the misdiagnoses.METHODS:Retrospective series study.Twenty-five misdisgnosed patients with unilateral ONSM were collected from Jan.2008 to Jan.2015 and the clinical records reviewed.RESULTS:Patients were misdiagnosed with acute papillitis most frequently(P=17),immediately followed by optic atrophy(P=8),ischemic optic neuropathy(P=5),acute retrobulbar optic neuritis(P=5),optic disc vasculitis(P =3).For each patient,the minimum frequency of misdiagnoses was once and the maximum was 4 times.As for the lasting time of being misdiagnosed,the shortest was 1.5mo and the longest was 45 mo.Twentyone cases(84%) were once treated with glucocorticoids,and its side effects was found in seventeen patients.Twenty patients(80%) complained with varying degree of vision loss.When a definite diagnosis was made,sixteen cases(64%) showed slight exophthalmos and eighteen cases(72%) had the tubular ONSM.CONCLUSION:ONSM without loss obvious exophthalmos is easily misdiagnosed in clinic,and for most of these ONSMs are tubular.展开更多
It is necessary to understand the bacterial populations associated with rice so as to provide more information and natural resources for effective management of major diseases in rice. A survey on screening and identi...It is necessary to understand the bacterial populations associated with rice so as to provide more information and natural resources for effective management of major diseases in rice. A survey on screening and identification of gram-positive bacteria was conducted during 1998 2004. Seven hundred and fifty-six rice samples were collected from Zhejiang, Jiangsu, Fujian and Yunnan Provinces, China. Over 1000 bacterial isolates were isolated and tested for colony morphology, pathogenicity, and some characteristics of bacteriology including Gram staining, fluorescent pigment on Kings medium B and microscopic observation for endospore. Together with five standard reference strains, 74 representative gram-positive bacterial isolates were confirmed by Biolog and gas chromatographic analysis of fatty acid methyl esters. Five bacterial species of Bacillus and other three genera were identified and isolates from Bacillus sublitis and Bacillus megaterium, exhibited the most effective inhibition against the pathogens of sheath blight and bakanae disease of rice. A few isolates from Bacillus pumilus and Bacillus megaterium showed weak virulent on rice together with some virulent isolates, risk should be considered when isolates from these species were screened for biocontrol agents.展开更多
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12275202,62371372,62101406,and 62001340)China Postdoctoral Science Foundation(Grant Nos.2022M71490 and 2020M673341)+1 种基金the Innovation Capability Support Program of Shaanxi Province,China(Grant No.2022TD-37)the Natural Science Basic Research Program of Shaanxi Province,China(Grant No.2023JC-YB-549)。
文摘“Magnetic window”is considered as an effective method to solve the communication blackout issue.COMSOL software package based on the finite element method is utilized to simulate the propagation of right-handed circularly polarized wave in the magnetized plasma sheath.We assume a double Gaussian model of electron density and an exponential attenuation model of magnetic field.The propagation characteristics of right-handed circularly polarized wave are analyzed by the observation of the reflected,transmitted and loss coefficient.The numerical results show that the propagation of right-handed circularly polarized wave in the magnetized plasma sheath varies for different incident angles,collision frequencies,non-uniform magnetic fields and non-uniform plasma densities.We notice that reducing the wave frequency can meet the propagation conditions of whistle mode in the weak magnetized plasma sheath.And the transmittance of whistle mode is less affected by the variation of the electron density and the collision frequency.It can be used as a communication window.
文摘BACKGROUND Epithelioid malignant peripheral nerve sheath tumor(EMPNST)of the bladder is a rare entity with devastating features.These tumors are thought to originate from malignant transformation of pre-existing schwannomas of pelvic autonomic nerve plexuses,and unlike the conventional malignant peripheral nerve sheath tumor(MPNST),are not associated with neurofibromatosis.The tumor has dis-tinctive morphological,immunohistochemical and molecular features.Addi-tionally,it tends to be more aggressive and have a higher mortality.This is the first case that presents with a synchronous urothelial carcinoma of the bladder and the epithelioid variant of MPNST in the literature.It’s also the second re-ported case of EMPNST originating from the bladder wall.CASE SUMMARY In this case report,we present the detailed clinical course of a 71-year-old patient with EMPNST of the bladder alongside a literature review.CONCLUSION During the management of EMPNST cases,offering aggressive treatment moda-lities to the patient,such as radical cystectomy,is appropriate for the best chance to contain the disease,regardless of the tumor stage and the extent of local disease at initial diagnosis.
基金Project supported by the National Natural Science Foundation of China (Grant No.51977132)Key Special Science and Technology Project of Liaoning Province (Grant No.2020JH1/10100012)General Program of the Education Department of Liaoning Province (Grant No.LJKZ0126)。
文摘When the contacts of a medium-voltage DC air circuit breaker(DCCB) are separated, the energy distribution of the arc is determined by the formation process of the near-electrode sheath. Therefore, the voltage drop through the near-electrode sheath is an important means to build up the arc voltage, which directly determines the current-limiting performance of the DCCB. A numerical model to describe the near-electrode sheath formation process can provide insight into the physical mechanism of the arc formation, and thus provide a method for arc energy regulation. In this work, we establish a two-dimensional axisymmetric time-varying model of a medium-voltage DCCB arc when interrupted by high current based on a fluid-chemical model involving 16 kinds of species and 46 collision reactions. The transient distributions of electron number density, positive and negative ion number density, net space charge density, axial electric field, axial potential between electrodes, and near-cathode sheath are obtained from the numerical model. The computational results show that the electron density in the arc column increases, then decreases, and then stabilizes during the near-cathode sheath formation process, and the arc column's diameter gradually becomes wider. The 11.14 V–12.33 V drops along the17 μm space charge layer away from the cathode(65.5 k V/m–72.5 k V/m) when the current varies from 20 k A–80 k A.The homogeneous external magnetic field has little effect on the distribution of particles in the near-cathode sheath core,but the electron number density at the near-cathode sheath periphery can increase as the magnetic field increases and the homogeneous external magnetic field will lead to arc diffusion. The validity of the numerical model can be proven by comparison with the experiment.
文摘With the popularization of central venous catheterization in recent years,the problems arising from intravenous therapy have gradually increased.Fibrin sheath is the complication with the highest incidence rate in central venous catheterization,which has always been a major problem in intravenous therapy.So the prevention and treatment of fibrin sheath has become a hot spot of research in recent years.Hence,this paper summarizes the research on fibrin sheath in recent years.
文摘During spacecraft re-entry,the challenge of measuring plasma sheath parameters directly contributes to difficulties in addressing communication blackout.In this work,we have discovered a phenomenon of multiple peaks in reflection data caused by the inhomogeneous plasma.Simulation results show that the multi-peak points fade away as the characteristic frequency is approached,resembling a series of gradually decreasing peaks.The positions and quantities of these points are positively correlated with electron density,yet they show no relation to collision frequency.This phenomenon is of significant reference value for future studies on the spatial distribution of plasmas,particularly for using microwave reflection signals in diagnosing the plasma sheath.
基金supported by a grant from the Progressive MS Alliance(BRAVE in MS)Le Grand Portage Fund。
文摘Mature oligodendrocytes form myelin sheaths that are crucial for the insulation of axons and efficient signal transmission in the central nervous system.Recent evidence has challenged the classical view of the functionally static mature oligodendrocyte and revealed a gamut of dynamic functions such as the ability to modulate neuronal circuitry and provide metabolic support to axons.Despite the recognition of potential heterogeneity in mature oligodendrocyte function,a comprehensive summary of mature oligodendrocyte diversity is lacking.We delve into early 20th-century studies by Robertson and Río-Hortega that laid the foundation for the modern identification of regional and morphological heterogeneity in mature oligodendrocytes.Indeed,recent morphologic and functional studies call into question the long-assumed homogeneity of mature oligodendrocyte function through the identification of distinct subtypes with varying myelination preferences.Furthermore,modern molecular investigations,employing techniques such as single cell/nucleus RNA sequencing,consistently unveil at least six mature oligodendrocyte subpopulations in the human central nervous system that are highly transcriptomically diverse and vary with central nervous system region.Age and disease related mature oligodendrocyte variation denotes the impact of pathological conditions such as multiple sclerosis,Alzheimer's disease,and psychiatric disorders.Nevertheless,caution is warranted when subclassifying mature oligodendrocytes because of the simplification needed to make conclusions about cell identity from temporally confined investigations.Future studies leveraging advanced techniques like spatial transcriptomics and single-cell proteomics promise a more nuanced understanding of mature oligodendrocyte heterogeneity.Such research avenues that precisely evaluate mature oligodendrocyte heterogeneity with care to understand the mitigating influence of species,sex,central nervous system region,age,and disease,hold promise for the development of therapeutic interventions targeting varied central nervous system pathology.
基金funded by the Sinopec Science and Technology Department Project(P21056).
文摘Generally,the so-called expansion agent is very effective in eliminating all the micro-annuli that exist between the casing and the cement sheath or between the cement sheath and the formation.However,this approach can detrimentally affect the sealing ability of cement sheath if the expansion agent is used in an unreasonable way.For these reasons,in the present work,numerical simulations have been conducted to analyze the effect of elasticity modulus of cement sheath,the elasticity modulus of formation,the expansion rate of cement,the geo-stress on the micro-annulus caused by cement expansion,and the cement sheath expansion on the integrity of cement sheath and formation.The micro-annulus between the casing and the cement sheath has been found to decrease according to the ratio between the elasticity modulus of formation and the elasticity modulus of cement sheath.A positive correlation has been observed between the micro-annulus and the cement expansion ratio.The microannulus decreases as the geo-stress increases,but the effect of the geo-stress on the micro-annulus is much smaller.In conclusion,the expansion agent is suitable for the formation in which the elasticity modulus is higher than the cement sheath.
基金supported by National Natural Science Foundation of China(No.51977110)。
文摘To understand the characteristics of the plasma sheath within small tubes,a 2D numerical model of He discharge within dielectric tubes is developed.During plasma propagation for a tube diameter of 0.05 mm,the sheath thickness in the plasma head is almost equal to the tube radius.It decreases rapidly to several micrometers at an axial distance of 0.05 mm behind the plasma head,and then slightly increases and saturates at the axial position far behind the plasma head.A plasma-gas sheath surrounding the central plasma column is observed for a tube diameter equal to or greater than 0.8 mm.It is replaced by a plasma-wall sheath for smaller tubes.With the decrease in the tube diameter,the sheath thickness far behind the plasma head decreases while the ion flux increases significantly.However,when O_(2)gas with a proportion of 2%is added,both the sheath thickness and ion flux decrease.
基金the research project from“Study of Risk assessment and Countermeasures of Well Drilling and Completion under Ultra-High Temperature and High Pressure”and“Research on Development Feasibility of LS25-1 Gas Field”(Grant Nos.YXKY-ZX-09-2021,2020FS-08).
文摘One of the main obstacles hindering the exploitation of high-temperature and high-pressure oil and gas is the sealing integrity of the cement sheath.Analyzing the microstructure of the cement sheath is therefore an important task.In this study,the microstructure of the cement sheath is determined using a CT scanner under different temperature and pressure conditions.The results suggest that the major cause of micro-cracks in the cement is the increase in the casing pressure.When the micro-cracks accumulate to a certain extent,the overall structure of the cement sheath is weakened,resulting in gas channeling,which poses a direct threat to the safe production of oil and gas.A change in the casing temperature has a limited effect on the microstructure of the cement sheath.
基金supported by a grant from the Double Thousand Plan of Jiangxi Province(No.jxsq2019101057)the National Natural Science Foundation of China(No.3196150349)to Haihui Fu and Xu Jie,respectively.
文摘OsPLS4 encodes aβ-ketoacyl carrier protein reductase(KAR).The role of OsPLS4 in rice sheath blight(Rhizoctonia solani)remains unclear.Our preliminary studies showed that premature leaf senescence mutants(pls4)were highly susceptive to sheath blight in the early stage of rice development.To explore the role of this gene in the development of rice sheath blight,the transcriptome profiles of the rice pls4 mutant and wild type were compared by RNA-seq.The results revealed 2,569 differentially expressed genes(DEGs).The down-regulated genes were significantly enriched in the defense response-related biological processes.These down-regulated genes included the chitinase genes and WRKY genes,which were significantly changed in pls4 mutants.Furthermore,467 genes induced significant alternative splicing(AS)events.Among them,intron retention(IR)affected gene expression levels and functions of the vitamin B6(VB6)metabolism pathway related to sheath blight.This result suggests that IR plays an important role in the sheath blight resistance of mutant pls4.Together,these results indicate that pls4 could be involved in the biological process of sheath blight via DEGs and the fine-tuning of IR.The present study provides a molecular basis for further investigation of the resistance of rice to sheath blight.
文摘BACKGROUND Malignant peripheral nerve sheath tumor(MPNST)is a rare and aggressive soft tissue sarcoma that poses a major diagnostic and therapeutic challenge.CASE SUMMARY We retrospectively reviewed patients with head and neck MPNSTs treated in our hospital from 2000 to 2021.The clinical features,pathological manifestations,treatments,and prognoses were summarized.We also reviewed the literature,focusing on MPNST in the mandible and maxilla.The study population consisted of five women and five men aged 22–75 years(mean age,49 years).Of the 10 patients,7 were initial cases and 3 were recurrent cases.All lesions were sporadic.The most common site was the mandible.The most frequently encountered symptoms were a progressive mass and local swelling.Complete or partial loss of trimethylation at lysine 27 of histone H3(H3K27me3)was evident on staining in four of nine cases(one case was excluded due to lack of tissue for evaluation of loss of H3K27me3).The 2-and 5-year disease-specific survival rates were 86%a nd 43%,respectively.The average survival time was 64 mo.CONCLUSION MPNST is a highly malignant tumor with a poor prognosis,prone to a high risk of recurrence and distant metastasis.Complete surgical resection is the main treatment.
基金supported by National Natural Science Foundation of China (Nos.11975062 and 11605021)the Fundamental Research Funds for the Central Universities (No.3132023192)。
文摘In the plasma sheath, there is a significant gradient in ion velocity, resulting in strong stress on ions treated as a fluid. This aspect has often been neglected in previous sheath studies. This study is based on the Braginskii plasma transport theory and establishes a 1D3V sheath fluid model that takes into account the ion stress effect. Under the assumption that ions undergo both electric and diamagnetic drift in the presheath region, self-consistent boundary conditions,including the ion Bohm velocity, are derived based on the property of the Sagdeev pseudopotential.Furthermore, assuming that the electron velocity at the wall follows a truncated Maxwell distribution, the wall floating potential is calculated, leading to a more accurate sheath thickness estimation. The results show that ion stress significantly reduces the sheath thickness, enhances ion Bohm velocity, wall floating potential, and ion flux at the wall. It hinders the acceleration of ions within the sheath, leading to notable alterations in the particle density profiles within the sheath. Further research indicates that in ion stress, bulk viscous stress has the greatest impact on sheath properties.
文摘Objective:To evaluate the effect of ureteral access sheath(UAS)use and calibration change on stone-free rate and complications of retrograde intrarenal surgery(RIRS).Methods:Data from 568 patients undergoing RIRS for kidney or upper ureteral stones were retrospectively included.Firstly,patients were compared after 1:1 propensity score matching,according to UAS usage during RIRS(UAS used[+]87 and UAS non-used[−]87 patients).Then all UAS+patients(n=481)were subdivided according to UAS calibration:9.5-11.5 Fr,10-12 Fr,11-13 Fr,and 13-15 Fr.Primary outcomes of the study were the success and complications of RIRS.Results:Stone-free rate of UAS+patients(86.2%)was significantly higher than UAS−patients(70.1%)after propensity score matching(p=0.01).Stone-free rate increased with higher caliber UAS(9.5-11.5 Fr:66.7%;10-12 Fr:87.0%;11-13 Fr:90.6%;13-15 Fr:100%;p<0.001).Postoperative complications of UAS+patients(11.5%)were significantly lower than UAS−patients(27.6%)(p=0.01).Complications(8.7%)with 9.5-11.5 Fr UAS was lower than thicker UAS(17.2%)but was not statistically significant(p=0.09).UAS usage was an independent factor predicting stone-free status or peri-and post-operative complications(odds ratio[OR]3.654,95%confidence interval[CI]1.314-10.162;OR 4.443,95%CI 1.350-14.552;OR 4.107,95%CI 1.366-12.344,respectively).Conclusion:Use of UAS in RIRS may increase stone-free rates,which also increase with higher caliber UAS.UAS usage may reduce complications;however,complications seemingly increase with higher UAS calibration.
文摘BACKGROUND:As advocated in advanced trauma life support and prehospital trauma life support protocols,cervical immobilization is applied until cervical spine injury is excluded.This study aimed to show the difference in optic nerve sheath diameter(ONSD)between patients with and without a cervical collar using computed tomography(CT).METHODS:This was a single-center,retrospective study examining trauma patients who presented to the emergency department between January 1,2021,and December 31,2021.The ONSD on brain CT of the trauma patients was measured and analyzed to determine whether there was a difference between the ONSD with and without the cervical collar.RESULTS:The study population consisted of 169 patients.On CT imaging of patients with(n=66)and without(n=103)cervical collars,the mean ONSD in the axial plane were 5.43±0.50 mm and 5.04±0.46 mm respectively for the right eye and 5.50±0.52 mm and 5.11±0.46 mm respectively for the left eye.The results revealed an association between the presence of a cervical collar and the mean ONSD,which was statistically significant(P<0.001)for both the right and left eyes.CONCLUSION:A cervical collar may be associated with increased ONSD.The effect of this increase in the ONSD on clinical outcomes needs to be investigated,and the actual need for cervical collar in the emergency department should be evaluated on a case-by-case basis.
基金Supported by Tianjin Key Medical Discipline Construction Project(No.TJYXZDXK-016A).
文摘AIM:To investigate the symmetry of upper eyelid in patients with unilateral mild and moderate blepharoptosis who underwent unilateral minimally invasive combined fascia sheath(CFS)suspension.METHODS:A retrospective study of patients who underwent unilateral minimally invasive CFS suspension surgery between January 2018 and December 2021.Inclusion criteria included unilateral mild and moderate ptosis,good levator muscle function(>9 mm)and follow-up of at least 6mo.Pre-and post-operative symmetry was graded subjectively for marginal reflex distance 1(MRD1),tarsal platform show(TPS)and eyebrow fat span(BFS).A t-test was used to evaluate MRD1,TPS and BFS asymmetry by calculating delta values.The Bézier curve tool of the Image J software was used to extract the upper eyelid contours,where the symmetry was measured by the percentage of overlapping curvatures(POC).RESULTS:Totally 105 patients(105 eyelids)were included(mild group,n=84;moderate group,n=21).Postoperatively,all patients increased MRD1 and decreased TPS in the ptotic eye while maintaining unchanged BFS.The asymmetric delta value for MRD1 was measured to be 1.48±0.86 preoperatively,and it decreased to 0.58±0.67 postoperatively in all cases(P=0.0004).In patients with mild ptosis,the asymmetry value of TPS fell significantly from 1.15±0.62 to 0.68±0.38(P=0.0187).The symmetry of the upper eyelid contour increased in all subgroups of patients,with a POC of 59.39%±13.45%preoperatively and POC of 78.29%±13.80%postoperatively.CONCLUSION:Minimally invasive CFS suspension is proved to be an effective means of improving the symmetry of unilateral ptosis in terms of MRD1(all subgroups),POC(all subgroups)and TPS(only mild group),whereas BFS is unaffected.
基金DST-SERB,GOI,New Delhi,India(File no.CRG/2020/001303)for their financial assistance。
文摘Equisetum(Equisetaceae)has long been a focus of attention for botanists and palaeontologists because,given its extensive and well-documented fossil record,it is considered the oldest extant vascular plant and a key element in understanding vascular plant evolution.However,to date,no authentic fossil evidence of Equisetum has been found from the Indian Cenozoic.Here,we describe a new fossil species,namely,E.siwalikum sp.nov.,recovered from the middle Siwalik(Late Miocene)sediments of Himachal Pradesh,western Himalaya.We identified fossil specimens based on morphological and epidermal characters.In addition,X-Ray diffraction(XRD)analysis was used to determine the mineral composition of compressed stems of Equisetum.The close affinity of our recovered Siwalik fossils to Equisetum is supported by the presence of both macromorphological and epidermal characters.Because Equisetum generally grows in wet conditions around water reservoirs,our findings indicate that the fossil locality was humid and surrounded by swamp and lowland regions during deposition.Ample fossil evidence indicates that this sphenopsid once existed in the western Himalaya during the Siwalik period.However,at present Equisetum is confined to a particular area of our fossil locality,probably a consequence of severe environmental changes coupled with competition from opportunistic angiosperms.Our discovery of Equisetum fossils in appreciable numbers from the Siwalik sediments of the Himachal Himalayas is unique and constitutes the first reliable recognition of Equisetum from the Indian Cenozoic.
基金the National High Technology Research and Development Program of China (863 Program) (No. 2006AA10Z165, 2006AA10A103 and 2007AA10Z191)the Ministry of Agriculture of China (No. nyhyzx07-049)the 948 Program (No. 2006-G51).
文摘The major QTL-qSB-9^Tq conferring partial resistance to rice (Oryza sativa L.) sheath blight (Rhizoctonia solani Kvhn) has been verified on chromosome 9 of the indica rice cultivar, Teqing. In this study, the prospect of this QTL utilized in molecular breeding program of japonica rice for sheath blight resistance was investigated. Most of the japonica rice cultivars showed lower level of sheath blight resistance than the indica rice cultivars. At the corresponding site of qSB-9^Tq, nine typical japonica rice cultivars from different ecological regions or countries proved to possess the susceptible allele(s). Introgression of qSB-9^Tq into these cultivars enhanced their resistance level by decreasing sheath blight score of 1.0 (0.5-1.3), which indicated that qSB-9^Tq had a large potential in strengthening the resistance of japonica rice to sheath blight. The use of the three molecular markers, which were polymorphic between Teqing and many japonica rice cultivars, promotes the application of qSB-9^Tq in a concrete molecular breeding program.
文摘Sheath blight of rice, caused by Rhizoctonia solani AG 1. 1a, has become the most important disease and caused serious yield losses in some major rice-growing regions in China in recent years. In the present study, field plot experiment was conducted to examine the relationships between disease intensity and inoculum density (ID), the seasonal disease epidemic dynamics, and yield reductions due to disease damages. Results from the experiment demonstrated that the areas under progress curves of disease severity and those of percent rice tillers diseased were positively and closely related to the relative initial ID of the pathogen. The inoculum density-disease (IDD) relationships were simulated and the impractical linear models were obtained. Both logistic and Gompertz functions could be used to simulate the disease progress dynamics in time, but the progress curves of the disease severity were modeled better by the Gompertz than by logistic function. However, the Richards function was found to be the best in simulating the disease progress curves when a most appropriate value was chosen for the shape parameter m by using the computer software Epitimulator. Sheath blight infection decreased rice yield very significantly and a yield reduction of 40% was recorded in rice crop with the highest inoculum density. Rice yield was linearly and negatively correlated with the disease severity and the percent tillers affected. The simulated models for all these relationships were computed through executing Epitimulator software and were presented in this paper.
文摘AIM:To investigate clinical features of optic nerve sheath meningioma(ONSM) that was misdiagnosed,and to find methods to reduce the misdiagnoses.METHODS:Retrospective series study.Twenty-five misdisgnosed patients with unilateral ONSM were collected from Jan.2008 to Jan.2015 and the clinical records reviewed.RESULTS:Patients were misdiagnosed with acute papillitis most frequently(P=17),immediately followed by optic atrophy(P=8),ischemic optic neuropathy(P=5),acute retrobulbar optic neuritis(P=5),optic disc vasculitis(P =3).For each patient,the minimum frequency of misdiagnoses was once and the maximum was 4 times.As for the lasting time of being misdiagnosed,the shortest was 1.5mo and the longest was 45 mo.Twentyone cases(84%) were once treated with glucocorticoids,and its side effects was found in seventeen patients.Twenty patients(80%) complained with varying degree of vision loss.When a definite diagnosis was made,sixteen cases(64%) showed slight exophthalmos and eighteen cases(72%) had the tubular ONSM.CONCLUSION:ONSM without loss obvious exophthalmos is easily misdiagnosed in clinic,and for most of these ONSMs are tubular.
基金the National Natural Science Foundation of China(30270891) National 863 Program(2002AA241261).
文摘It is necessary to understand the bacterial populations associated with rice so as to provide more information and natural resources for effective management of major diseases in rice. A survey on screening and identification of gram-positive bacteria was conducted during 1998 2004. Seven hundred and fifty-six rice samples were collected from Zhejiang, Jiangsu, Fujian and Yunnan Provinces, China. Over 1000 bacterial isolates were isolated and tested for colony morphology, pathogenicity, and some characteristics of bacteriology including Gram staining, fluorescent pigment on Kings medium B and microscopic observation for endospore. Together with five standard reference strains, 74 representative gram-positive bacterial isolates were confirmed by Biolog and gas chromatographic analysis of fatty acid methyl esters. Five bacterial species of Bacillus and other three genera were identified and isolates from Bacillus sublitis and Bacillus megaterium, exhibited the most effective inhibition against the pathogens of sheath blight and bakanae disease of rice. A few isolates from Bacillus pumilus and Bacillus megaterium showed weak virulent on rice together with some virulent isolates, risk should be considered when isolates from these species were screened for biocontrol agents.