After several former studies on the cognitive heuristics and correlating economical influences,the explanatory effectiveness of Status Quo Bias perspective is explained by multiple empirical scenarios.Hence,this essay...After several former studies on the cognitive heuristics and correlating economical influences,the explanatory effectiveness of Status Quo Bias perspective is explained by multiple empirical scenarios.Hence,this essay will focus on three applications in which the Status Quo Bias perspective,correlating models,and research methods would provide insightful opinions.After reviewing the former attempts on the original model and early researchers’empirical examination on the Status Quo Bias,this essay will concentrate on Status Quo Bias and technology resistance among the public sector employees,Status Quo Bias and medical insurance outcomes,Status Quo Bias and shoppers’mobile website purchasing resistance respectively.For each application,research methodology will be explained and be integrated into the Status Quo Bias perspective through the research question.Through researching on these applications’methodology and main studies,discussing cognitive biases existing in the empirical scenarios,the present study could approach to the efficiency of the explanation from Status Quo Bias perspective.展开更多
As an international language,English has a great influence on the whole world.English literary works reflect the social and economic fields of western countries.Therefore,we explore the aesthetic value of English lite...As an international language,English has a great influence on the whole world.English literary works reflect the social and economic fields of western countries.Therefore,we explore the aesthetic value of English literature help us to better under-stand the literature of western countries,as well as the social and economic aspects,and enhance the communication between China and the West.This article is about the exploration on aesthetic value of English literature.展开更多
Among the three methods of intangible cultural heritage (ICH) protection--salvage, integrity and productivity^--productive protection is the most complex and controversial one. Through a comprehensive analysis of le...Among the three methods of intangible cultural heritage (ICH) protection--salvage, integrity and productivity^--productive protection is the most complex and controversial one. Through a comprehensive analysis of legal relations, coordination mecha- nisms and modes of operation by the Wuhan Tourism Investment Group in the course of safeguarding intangible cultural heritage in handicrafts, this paper discusses the sustainable "Wuhan Model" and its human values.展开更多
Disaster runs through the whole process of human development.As a common topic faced by mankind anywhere and anytime,disaster has become the object of consideration and writing by writers in every country.This paper f...Disaster runs through the whole process of human development.As a common topic faced by mankind anywhere and anytime,disaster has become the object of consideration and writing by writers in every country.This paper first identifies the etymological meaning of“disaster”in Western language and culture,and then examines the main representations of Western“disaster”literature in terms of literary genre,developing trajectory and thematic characteristics.Finally,the paper summarizes the researches of Western“disaster”literature,and provide references for worldwide study of“disaster”literature.展开更多
Several prediction models have been developed to estimate the outcomes of prostate biopsies. Most of these tools were designed for use with Western populations and have not been validated across different ethnic group...Several prediction models have been developed to estimate the outcomes of prostate biopsies. Most of these tools were designed for use with Western populations and have not been validated across different ethnic groups. Therefore, we evaluated the predictive value of the Prostate Cancer Prevention Trial (PCPT) and the European Randomized Study of Screening for Prostate Cancer (ERSPC) risk calculators in a Chinese cohort. Clinicopathological information was obtained from 495 Chinese men who had undergone extended prostate biopsies between January 2009 and March 2011. The estimated probabilities of prostate cancer and high-grade disease (Gleason 〉6) were calculated using the PCPT and ERSPC risk calculators. Overall measures, discrimination, calibration and clinical usefulness were assessed for the model evaluation. Of these patients, 28.7% were diagnosed with prostate cancer and 19.4% had high-grade disease. Compared to the PCPT model and the prostate-specific antigen (PSA) threshold of 4 ng m1-1, the ERSPC risk calculator exhibited better discriminative ability for predicting positive biopsies and high-grade disease (the area under the curve was 0.831 and 0.852, respectively, P〈O.01 for both). Decision curve analysis also suggested the favourable clinical utility of the ERSPC calculator in the validation dataset. Both prediction models demonstrated miscalibration: the risk of prostate cancer and high-grade disease was overestimated by approximately 20% for a wide range of predicted probabilities. In conclusion, the ERSPC risk calculator outperformed both the PCPT model and the PSA threshold of 4 ng ml- z in predicting prostate cancer and high-grade disease in Chinese patients. However, the prediction tools derived from Western men significantly overestimated the probability of prostate cancer and high-grade disease compared to the outcomes of biopsies in a Chinese cohort.展开更多
Assessment on wetland values is being payed more and more attention by researchers, administrators and public. This question is related to human’s sustainable development in biosphere. This article analyses the commo...Assessment on wetland values is being payed more and more attention by researchers, administrators and public. This question is related to human’s sustainable development in biosphere. This article analyses the commonweal values of wetlands and establishes an index system by Analytical Hierarchy Process, then assigns quantitatively the system through calculating matrix eigenvalue and characteristic vector, at last, sets up an integral way of commonweal value assessment .This paper takes Zhalong Wetland and Xianghai Wetland as study cases , the assessment results show that the both wetlands belong to the first grade importance protective wetland, which validates the method’s practicability , scientific nature and rationality.展开更多
This essay discusses the issue concerning the use of literature as a pedagogic tool in the EFL reading classroom, which is different from the traditional study of literature. It aims to illustrate that literary texts ...This essay discusses the issue concerning the use of literature as a pedagogic tool in the EFL reading classroom, which is different from the traditional study of literature. It aims to illustrate that literary texts can be used as a useful language teaching resource rather than as an object of literary study. In the essay, the first part talks about the values of using literature in the EFL reading classroom. The second part is a set of activities related to a specific literary text which aim to develop some of the values identified in the first part.展开更多
Background: The association between food insecurity (FI) and obesity is now so well documented that scholars have dubbed it the “‘new’ food insecurity” and cited it as a leading cause of increased chronic disease ...Background: The association between food insecurity (FI) and obesity is now so well documented that scholars have dubbed it the “‘new’ food insecurity” and cited it as a leading cause of increased chronic disease (CD) risk. Here, the chain of causality is assumed to be FI → obesity → CD. However, this model overlooks the possible direct associations between FI and CD independent of obesity. Aim: This study assessed the literature on relationships between FI and CD. Methods: We conducted a systematic literature review of electronic databases. Selection criteria were designed to elicit studies that assessed FI and CD using a measure of CD other than obesity. Results: Fifty-one articles met the inclusion criteria. Forty-five studies (87%) reported a statistically significant association between FI and CD, but only 15 adjusted for obesity. The association was less consistent for asthma and dyslipidemia than for diabetes, hypertension, and other dietrelated CDs, and most were conducted in the USA or Canada. Conclusion: There is a body of literature documenting relationships between FI and CD, but it is heavily biased toward Western nations, ecological study designs, and type 2 diabetes as the CD of focus. A small subset of the literature controls for BMI, demonstrating that a portion of the FI-CD relationship cannot be fully explained by obesity. Possible direct pathways linking FI and CD include systematic effects of poverty that accompanies FI, micronutrient deficiencies, and environmental exposure to toxins;however, exploration of these alternative pathways is limited by study designs that fail to include obesity as a control variable.展开更多
According to the research of Wen Jun and Li Peijia, this paper examins the articles and treatises regarding the English translations of Romance of the Three Kingdoms in China in the past five years. It is divided into...According to the research of Wen Jun and Li Peijia, this paper examins the articles and treatises regarding the English translations of Romance of the Three Kingdoms in China in the past five years. It is divided into four sections: Summary, Language, Literature and Culture. We point out the existing problems of the current studies;limited in traditional linguistic levels, leaning to the translation of Moss Roberts, neglecting the study of non-cover-to-cover translations, revelry at home and coldness abroad. Besides, we put forward the translation studies of Romance of the Three Kingdoms based on comparative literature to fill the gaps in the current research. The translation study of comparative literature pays attention to four aspects;literary translations and translated literature, cover-to-cover translations and non-cover-to-cover translations, C.H. Brewitt-Taylor and Moss Roberts, domestic and overseas.展开更多
In the present article,the attention is focused on autorepresentational image that can be derived from Cristina Campo’s literary language,while analyzing at the same time its genesis,given finalities and reception.It...In the present article,the attention is focused on autorepresentational image that can be derived from Cristina Campo’s literary language,while analyzing at the same time its genesis,given finalities and reception.It is what can be deduced in filigrain from essayistic-critical writings in The Unforgivable Ones(Gli imperdonabili)and Under a False Name(Sotto falso nome),as well as from collections of letters and illuminating lyrical motifs,based on which it will be demonstrated that analogous themes are associated to various literary genres on grounds of principle of inter-genre contamination.By illustrating the founding postulates of autopoetic reflections,the intention is to ulteriorly determine their collocation within the frame of cultural history.To veiled autobiographism contributes pseudonymical practice,as well as subsequent stylistic devices,through which modernistic aspects are highlighted.The autobiographical narration in The Golden Walnut(La noce d’oro),short story-fairy tale of aesthetic timbre frequently infused with figural tropism,comprises a literary mixture of rievocation and mythography,relying on anthropological premises that are speculatively articulated.展开更多
Delicacy is one significant theme of literary and artistic creation.Since the 1980s,excellent delicacy writing industry has become an important part of Chinese teaching in middle schools.Since the beginning of the new...Delicacy is one significant theme of literary and artistic creation.Since the 1980s,excellent delicacy writing industry has become an important part of Chinese teaching in middle schools.Since the beginning of the new century,the carrier of food writing has changed from the literal one to full-view video,audiovisual television documentaries.The essence of new form of contemporary food writing does not change;it still implies the meticulous and warm humanistic care.The value of it in Chinese courses still has much room to expand.展开更多
With the development of global economic integration in recent years, Chinese culture is influenced by the penetration of Western culture, and there are many excellent English literature works. This paper focuses on ho...With the development of global economic integration in recent years, Chinese culture is influenced by the penetration of Western culture, and there are many excellent English literature works. This paper focuses on how to translate excellent English literature into appropriate Chinese. It shows the key meaning of English literary translation which embodies artistic characteristics and aesthetic value. Then it analyzes how to reflect aesthetic value and artistic characteristics in English literary translation.展开更多
Li Bai and George Gordon Byron can be regarded as the most outstanding romantic poets of China and Britain respectively. By making a comparative study, both the similarities and differences between their literary work...Li Bai and George Gordon Byron can be regarded as the most outstanding romantic poets of China and Britain respectively. By making a comparative study, both the similarities and differences between their literary works are to be figured out. For one thing, despite the different times and cultural background they lived in, there exists similarities between their works in pursuit of freedom and writing techniques, such as the portrait of sublime and the use of mythological imageries. For another, besides these similarities, there still remains subtle differences between their works in political ideal, tone and themes.展开更多
The paper starts with an introduction to Greek mythology,and then deeply explores the influence of Greek mythology on western culture and its roles in the development of British and American classical literature in th...The paper starts with an introduction to Greek mythology,and then deeply explores the influence of Greek mythology on western culture and its roles in the development of British and American classical literature in the west.At last,the author analyzes the profound influences of Greek mythology on British and American literature from vocabulary,character role,creative inspiration,way of thinking,the outlook on life,values,and other aspects.展开更多
Air-tightness and energy consumption was measured in a one-family house built in 2009 and 2010.The air-tightness fulfilled the goals,which was set to 0.3 L/s·m^(2).The energy consumption was measured from the sta...Air-tightness and energy consumption was measured in a one-family house built in 2009 and 2010.The air-tightness fulfilled the goals,which was set to 0.3 L/s·m^(2).The energy consumption was measured from the start in May 2010.The figures in this report refer to measurements between May 2010 and October 2013 and are well below the authority demand of 55 kWh/m^(2)·year.展开更多
Considered a great example of investigative fiction,Mia per sempre[Mine Forever]which denounces violence against women,encourages them to speak out,seek assistance,and refuse to flee in terror,has been hailed as outst...Considered a great example of investigative fiction,Mia per sempre[Mine Forever]which denounces violence against women,encourages them to speak out,seek assistance,and refuse to flee in terror,has been hailed as outstanding work to denounce violence against women.The book is a study of women’s unusual relationships,which are marked by intense love,envious friendships,and unbreakable ties that result in mental instability,irrational behavior,or uncontrollable behavior.Tani’s work has also received recognition for including the knowledgeable perspectives of various specialists who offer a deeper and priceless understanding of these catastrophes occurring individuals’home.This study examines those instances of fear-sharing in relation to women’s independence and ability to move on or start new lives.The main question is how and why Tani’s employs fear.Who are the women or circumstances that cause fear?This paper considers the theoretical discourse on fear developed by scholars of the emotions such as,among others,Jaimal Yogis and Olsson and Phelps in order to examine the circumstances and outcomes of fear fashioned by Tani in her representation of Italian men’s criminal reaction to women’s autonomy.展开更多
AIM:To assess the diagnostic value of serum interleukin-8(IL-8)in the detection of colorectal cancer(CRC).METHODS:An original study was conducted to explore the potential value of IL-8 in CRC diagnosis.Receiver operat...AIM:To assess the diagnostic value of serum interleukin-8(IL-8)in the detection of colorectal cancer(CRC).METHODS:An original study was conducted to explore the potential value of IL-8 in CRC diagnosis.Receiver operating characteristic(ROC)analysis was performed and the area under the curve(AUC)value was calculated.PUBMED and EMBASE were searched(to October,2013),supplemented with manual screening for relevant publications.Meta-analysis methods were applied to pool sensitivity,specificity,positive and negative likelihood ratios,and diagnostic odds ratios and to construct a summary receiver-operating characteristic(s ROC)curve.Heterogeneity across studies was checked by the I2 test and Deek’s funnel plot method was applied to test publication bias.RESULTS:In our original study,serum IL-8 yielded an AUC of 0.742[95%CI:0.635-0.849].The sensitivity and specificity were 85.42%and 54.05%,respectively,at a cut-off value of 5.39.In this meta-analysis,we included five studies with 668 CRC patients and 374controls and one study in our own center with 48 CRC patients and 37 controls.The pooled sensitivity and specificity of IL-8 were 0.69(95%CI:0.42-0.87)and0.85(95%CI:0.68-0.94)for CRC detection.Besides,the area under the s ROC curve was 0.86(95%CI:0.82-0.88).Subgroup analysis suggested that there was no heterogeneity in the Asian subgroup but some in the European subgroup.In addition,no publication bias was found according to the Deek’s funnel plot asymmetry test.CONCLUSION:Serum IL-8 is a promising biomarker for CRC detection and may become a clinically useful tool to identify high-risk patients.展开更多
文摘After several former studies on the cognitive heuristics and correlating economical influences,the explanatory effectiveness of Status Quo Bias perspective is explained by multiple empirical scenarios.Hence,this essay will focus on three applications in which the Status Quo Bias perspective,correlating models,and research methods would provide insightful opinions.After reviewing the former attempts on the original model and early researchers’empirical examination on the Status Quo Bias,this essay will concentrate on Status Quo Bias and technology resistance among the public sector employees,Status Quo Bias and medical insurance outcomes,Status Quo Bias and shoppers’mobile website purchasing resistance respectively.For each application,research methodology will be explained and be integrated into the Status Quo Bias perspective through the research question.Through researching on these applications’methodology and main studies,discussing cognitive biases existing in the empirical scenarios,the present study could approach to the efficiency of the explanation from Status Quo Bias perspective.
文摘As an international language,English has a great influence on the whole world.English literary works reflect the social and economic fields of western countries.Therefore,we explore the aesthetic value of English literature help us to better under-stand the literature of western countries,as well as the social and economic aspects,and enhance the communication between China and the West.This article is about the exploration on aesthetic value of English literature.
文摘Among the three methods of intangible cultural heritage (ICH) protection--salvage, integrity and productivity^--productive protection is the most complex and controversial one. Through a comprehensive analysis of legal relations, coordination mecha- nisms and modes of operation by the Wuhan Tourism Investment Group in the course of safeguarding intangible cultural heritage in handicrafts, this paper discusses the sustainable "Wuhan Model" and its human values.
文摘Disaster runs through the whole process of human development.As a common topic faced by mankind anywhere and anytime,disaster has become the object of consideration and writing by writers in every country.This paper first identifies the etymological meaning of“disaster”in Western language and culture,and then examines the main representations of Western“disaster”literature in terms of literary genre,developing trajectory and thematic characteristics.Finally,the paper summarizes the researches of Western“disaster”literature,and provide references for worldwide study of“disaster”literature.
文摘Several prediction models have been developed to estimate the outcomes of prostate biopsies. Most of these tools were designed for use with Western populations and have not been validated across different ethnic groups. Therefore, we evaluated the predictive value of the Prostate Cancer Prevention Trial (PCPT) and the European Randomized Study of Screening for Prostate Cancer (ERSPC) risk calculators in a Chinese cohort. Clinicopathological information was obtained from 495 Chinese men who had undergone extended prostate biopsies between January 2009 and March 2011. The estimated probabilities of prostate cancer and high-grade disease (Gleason 〉6) were calculated using the PCPT and ERSPC risk calculators. Overall measures, discrimination, calibration and clinical usefulness were assessed for the model evaluation. Of these patients, 28.7% were diagnosed with prostate cancer and 19.4% had high-grade disease. Compared to the PCPT model and the prostate-specific antigen (PSA) threshold of 4 ng m1-1, the ERSPC risk calculator exhibited better discriminative ability for predicting positive biopsies and high-grade disease (the area under the curve was 0.831 and 0.852, respectively, P〈O.01 for both). Decision curve analysis also suggested the favourable clinical utility of the ERSPC calculator in the validation dataset. Both prediction models demonstrated miscalibration: the risk of prostate cancer and high-grade disease was overestimated by approximately 20% for a wide range of predicted probabilities. In conclusion, the ERSPC risk calculator outperformed both the PCPT model and the PSA threshold of 4 ng ml- z in predicting prostate cancer and high-grade disease in Chinese patients. However, the prediction tools derived from Western men significantly overestimated the probability of prostate cancer and high-grade disease compared to the outcomes of biopsies in a Chinese cohort.
基金Sponsored by Foundation of Institute Director, Changchun Institute of Geography, the Chinese Academy of Sciences.
文摘Assessment on wetland values is being payed more and more attention by researchers, administrators and public. This question is related to human’s sustainable development in biosphere. This article analyses the commonweal values of wetlands and establishes an index system by Analytical Hierarchy Process, then assigns quantitatively the system through calculating matrix eigenvalue and characteristic vector, at last, sets up an integral way of commonweal value assessment .This paper takes Zhalong Wetland and Xianghai Wetland as study cases , the assessment results show that the both wetlands belong to the first grade importance protective wetland, which validates the method’s practicability , scientific nature and rationality.
文摘This essay discusses the issue concerning the use of literature as a pedagogic tool in the EFL reading classroom, which is different from the traditional study of literature. It aims to illustrate that literary texts can be used as a useful language teaching resource rather than as an object of literary study. In the essay, the first part talks about the values of using literature in the EFL reading classroom. The second part is a set of activities related to a specific literary text which aim to develop some of the values identified in the first part.
文摘Background: The association between food insecurity (FI) and obesity is now so well documented that scholars have dubbed it the “‘new’ food insecurity” and cited it as a leading cause of increased chronic disease (CD) risk. Here, the chain of causality is assumed to be FI → obesity → CD. However, this model overlooks the possible direct associations between FI and CD independent of obesity. Aim: This study assessed the literature on relationships between FI and CD. Methods: We conducted a systematic literature review of electronic databases. Selection criteria were designed to elicit studies that assessed FI and CD using a measure of CD other than obesity. Results: Fifty-one articles met the inclusion criteria. Forty-five studies (87%) reported a statistically significant association between FI and CD, but only 15 adjusted for obesity. The association was less consistent for asthma and dyslipidemia than for diabetes, hypertension, and other dietrelated CDs, and most were conducted in the USA or Canada. Conclusion: There is a body of literature documenting relationships between FI and CD, but it is heavily biased toward Western nations, ecological study designs, and type 2 diabetes as the CD of focus. A small subset of the literature controls for BMI, demonstrating that a portion of the FI-CD relationship cannot be fully explained by obesity. Possible direct pathways linking FI and CD include systematic effects of poverty that accompanies FI, micronutrient deficiencies, and environmental exposure to toxins;however, exploration of these alternative pathways is limited by study designs that fail to include obesity as a control variable.
文摘According to the research of Wen Jun and Li Peijia, this paper examins the articles and treatises regarding the English translations of Romance of the Three Kingdoms in China in the past five years. It is divided into four sections: Summary, Language, Literature and Culture. We point out the existing problems of the current studies;limited in traditional linguistic levels, leaning to the translation of Moss Roberts, neglecting the study of non-cover-to-cover translations, revelry at home and coldness abroad. Besides, we put forward the translation studies of Romance of the Three Kingdoms based on comparative literature to fill the gaps in the current research. The translation study of comparative literature pays attention to four aspects;literary translations and translated literature, cover-to-cover translations and non-cover-to-cover translations, C.H. Brewitt-Taylor and Moss Roberts, domestic and overseas.
文摘In the present article,the attention is focused on autorepresentational image that can be derived from Cristina Campo’s literary language,while analyzing at the same time its genesis,given finalities and reception.It is what can be deduced in filigrain from essayistic-critical writings in The Unforgivable Ones(Gli imperdonabili)and Under a False Name(Sotto falso nome),as well as from collections of letters and illuminating lyrical motifs,based on which it will be demonstrated that analogous themes are associated to various literary genres on grounds of principle of inter-genre contamination.By illustrating the founding postulates of autopoetic reflections,the intention is to ulteriorly determine their collocation within the frame of cultural history.To veiled autobiographism contributes pseudonymical practice,as well as subsequent stylistic devices,through which modernistic aspects are highlighted.The autobiographical narration in The Golden Walnut(La noce d’oro),short story-fairy tale of aesthetic timbre frequently infused with figural tropism,comprises a literary mixture of rievocation and mythography,relying on anthropological premises that are speculatively articulated.
文摘Delicacy is one significant theme of literary and artistic creation.Since the 1980s,excellent delicacy writing industry has become an important part of Chinese teaching in middle schools.Since the beginning of the new century,the carrier of food writing has changed from the literal one to full-view video,audiovisual television documentaries.The essence of new form of contemporary food writing does not change;it still implies the meticulous and warm humanistic care.The value of it in Chinese courses still has much room to expand.
文摘With the development of global economic integration in recent years, Chinese culture is influenced by the penetration of Western culture, and there are many excellent English literature works. This paper focuses on how to translate excellent English literature into appropriate Chinese. It shows the key meaning of English literary translation which embodies artistic characteristics and aesthetic value. Then it analyzes how to reflect aesthetic value and artistic characteristics in English literary translation.
文摘Li Bai and George Gordon Byron can be regarded as the most outstanding romantic poets of China and Britain respectively. By making a comparative study, both the similarities and differences between their literary works are to be figured out. For one thing, despite the different times and cultural background they lived in, there exists similarities between their works in pursuit of freedom and writing techniques, such as the portrait of sublime and the use of mythological imageries. For another, besides these similarities, there still remains subtle differences between their works in political ideal, tone and themes.
文摘The paper starts with an introduction to Greek mythology,and then deeply explores the influence of Greek mythology on western culture and its roles in the development of British and American classical literature in the west.At last,the author analyzes the profound influences of Greek mythology on British and American literature from vocabulary,character role,creative inspiration,way of thinking,the outlook on life,values,and other aspects.
文摘Air-tightness and energy consumption was measured in a one-family house built in 2009 and 2010.The air-tightness fulfilled the goals,which was set to 0.3 L/s·m^(2).The energy consumption was measured from the start in May 2010.The figures in this report refer to measurements between May 2010 and October 2013 and are well below the authority demand of 55 kWh/m^(2)·year.
文摘Considered a great example of investigative fiction,Mia per sempre[Mine Forever]which denounces violence against women,encourages them to speak out,seek assistance,and refuse to flee in terror,has been hailed as outstanding work to denounce violence against women.The book is a study of women’s unusual relationships,which are marked by intense love,envious friendships,and unbreakable ties that result in mental instability,irrational behavior,or uncontrollable behavior.Tani’s work has also received recognition for including the knowledgeable perspectives of various specialists who offer a deeper and priceless understanding of these catastrophes occurring individuals’home.This study examines those instances of fear-sharing in relation to women’s independence and ability to move on or start new lives.The main question is how and why Tani’s employs fear.Who are the women or circumstances that cause fear?This paper considers the theoretical discourse on fear developed by scholars of the emotions such as,among others,Jaimal Yogis and Olsson and Phelps in order to examine the circumstances and outcomes of fear fashioned by Tani in her representation of Italian men’s criminal reaction to women’s autonomy.
文摘AIM:To assess the diagnostic value of serum interleukin-8(IL-8)in the detection of colorectal cancer(CRC).METHODS:An original study was conducted to explore the potential value of IL-8 in CRC diagnosis.Receiver operating characteristic(ROC)analysis was performed and the area under the curve(AUC)value was calculated.PUBMED and EMBASE were searched(to October,2013),supplemented with manual screening for relevant publications.Meta-analysis methods were applied to pool sensitivity,specificity,positive and negative likelihood ratios,and diagnostic odds ratios and to construct a summary receiver-operating characteristic(s ROC)curve.Heterogeneity across studies was checked by the I2 test and Deek’s funnel plot method was applied to test publication bias.RESULTS:In our original study,serum IL-8 yielded an AUC of 0.742[95%CI:0.635-0.849].The sensitivity and specificity were 85.42%and 54.05%,respectively,at a cut-off value of 5.39.In this meta-analysis,we included five studies with 668 CRC patients and 374controls and one study in our own center with 48 CRC patients and 37 controls.The pooled sensitivity and specificity of IL-8 were 0.69(95%CI:0.42-0.87)and0.85(95%CI:0.68-0.94)for CRC detection.Besides,the area under the s ROC curve was 0.86(95%CI:0.82-0.88).Subgroup analysis suggested that there was no heterogeneity in the Asian subgroup but some in the European subgroup.In addition,no publication bias was found according to the Deek’s funnel plot asymmetry test.CONCLUSION:Serum IL-8 is a promising biomarker for CRC detection and may become a clinically useful tool to identify high-risk patients.