Does the traditional Chinese medicine theory of five circuits and six qi improve treatment effectiveness?A systematic review of randomized controlled trials

Objective:To evaluate whether the traditional Chinese medicine(TCM)theory of five circuits and six qi(FCSQ)is beneficial in terms of improving clinical effectiveness.Methods:Randomized controlled trials(RCTs)evaluating the clinical value of FCSQ theory were reviewed.Multiple databases(China Network Knowledge Infrastructure,Chinese Scienti fic Journals Database,Wanfang Data,SinoMed,Cochrane Library,PubMed,and Embase)weresystematically searched from inception to June 12,2018.Two authors independently extracted the data and performed a methodological quality assessment of the RCTs.RevMan 5.3 software was used for the data analysis.The effect sizes for the primary outcome measures were expressed as relative risks or mean differences with 95%confidence intervals.Results:A total of 13 RCTs were selected,involving 12 types of diseases and 4695 patients.The methodological quality of the RCTs was generally low.Five studies compared the effectiveness of TCM treatments guided by FCSQ theory with conventional TCM therapies,and the remaining eight studies compared the effectiveness of TCM treatments guided by FCSQ theory with biomedical treatments.All of the RCTs reported that the effectiveness of the treatment intervention was better than that of the intervention in the control group.Conclusion:Because of many methodological problems in existing clinical studies,it remains impossible to definitively conclude that FCSQ theory can improve clinical effectiveness.It is difficult to unify the clinical application of FCSQ theory.The feasibility and repeatability of FCSQas an intervention should be given more attention in future clinical research.Future work should also follow international norms for clinical research implementation and reporting to provide high-quality evidence for evaluating the clinical value of FCSQ theory.

Spatiotemporal Evolution of Urban Heat Islands and Optimization of Spatial Network Construction in the Central Urban Area of Fuzhou City, China

Although accelerated urbanization has led to economic prosperity,it has also resulted in urban heat island effects.Therefore,identifying methods of using limited urban spaces to alleviate heat islands has become an urgent issue.In this study,we assessed the spatiotemporal evolution of urban heat islands within the central urban area of Fuzhou City,China from 2010 to 2019.This assessment was based on a morphological spatial pattern analysis(MSPA)model and an urban thermal environment spatial network constructed us-ing the minimum cumulative resistance(MCR)model.Optimization measures for the spatial network were proposed to provide a theor-etical basis for alleviating urban heat islands.The results show that the heat island area within the study area gradually increased while that of urban cold island area gradually decreased.The core area was the largest of the urban heat island patch landscape elements with a significant impact on other landscape elements,and represented an important factor underlying urban heat island network stability.The thermal environment network revealed a total of 197 thermal environment corridors and 93 heat island sources.These locations were then optimized according to the current land use,which maximized the potential of 1599.83 ha.Optimization based on current land use led to an increase in climate resilience,with effective measures showing reduction in thermal environment spatial network structure and function,contributing to the mitigation of urban heat island.These findings support the use of current land use patterns during urban heat island mitigation measure planning,thus providing an important reference basis for alleviating urban heat island effects.

Impacts of multi-scenario land use change on ecosystem services and ecological security pattern: A case study of the Yellow River Delta

The Yellow River Delta(YRD), a critical economic zone along China's eastern coast, also functions as a vital ecological reserve in the lower Yellow River. Amidst rapid industrialization and urbanization, the region has witnessed significant land use/cover changes(LUCC), impacting ecosystem services(ES) and ecological security patterns(ESP). Investigating LUCC's effects on ES and ESP in the YRD is crucial for ecological security and sustainable development. This study utilized the PLUS model to simulate 2030 land use scenarios, including natural development(NDS), economic development(EDS), and ecological protection scenarios(EPS). Subsequently, the InVEST model and circuit theory were applied to assess ES and ESP under varying LUCC scenarios from 2010 to 2030. Findings indicate:(1) Notable LUCC from 2010 to 2030, marked by decreasing cropland and increasing construction land and water bodies.(2) From 2010 to 2020, improvements were observed in carbon storage,water yield, soil retention, and habitat quality, whereas 2020–2030 saw increases in water yield and soil retention but declines in habitat quality and carbon storage. Among the scenarios, EPS showed superior performance in all four ES.(3) Between 2010 and 2030, ecological sources, corridors, and pinchpoints expanded, displaying significant spatial heterogeneity. The EPS scenario yielded the most substantial increases in ecological sources,corridors, and pinchpoints, totaling 582.89 km^(2), 645.03 km^(2),and 64.43 km^(2), respectively. This study highlights the importance of EPS, offering insightful scientific guidance for the YRD's sustainable development.

ANALYSIS OF CIRCUIT TOLERANCE BASED ON RANDOM SET THEORY

Monte Carlo Analysis has been an accepted method for circuit tolerance analysis, but the heavy computational complexity has always prevented its applications. Based on random set theory, this paper presents a simple and flexible tolerance analysis method to estimate circuit yield. It is the alternative to Monte Carlo analysis, but reduces the number of calculations dramatically.

Study on the Biological Basis of Qi, Blood, and Vessel in Immune Thrombocytopenia Patients With Syndrome of Qi Failing to Govern Blood Based on the Theory of Qi and Blood

Objective: To investigate the biological basis of qi, blood and vessel in immune thrombocytopenia(ITP) patients with syndrome of qi failing to govern blood(SQFGB) based on traditional Chinese medicine.Methods: A total of 52 ITP patients with SQFCB were enrolled and divided into bleeding group(38 cases) and non-bleeding group(14 cases).Bleeding group was further divided into mild qi deficiency group(25 cases) and moderate/severe qi deficiency group(13 cases) based on Chinese Medicine syndrome score.20 healthy volunteer were recruited as control group.The count of platelet(PLT) was taken as the blood related indicator.The expressions of cytokines including IL-1β, IL-17 A, TNF-α, CD40 L, and TGF-β, detected by Aim Plex Multiple Immunoassays for Flow, were taken as the qi related indicators.The expressions of VEGF-A, detected by Aim Plex Multiple Immunoassays for Flow and NO, NOS, and ET-1 detected by ELISA, were taken as the vessel related indicators.Results: As compared to the control group, the count of PLT, taken as the blood related indicator, was significantly lower in ITP group patients with SQFCB(P<0.05).The expression levels of IL-17 A and TNF-α, taken as the qi related indicators, were significantly higher, while those of CD40 L, IL-1β, and TGF-β, also taken as the qi related indicators, were significantly lower in ITP patients with SQFCB, respectively(P<0.05).The expression levels of NO and ET-1, taken as the vessel related indicators, were significantly higher, while the expression levels of NOS and VEGF-A also taken as the vessel related indicators, were significantly lower in ITP patients with SQFCB, respectively(P<0.05).The count of PLT, taken as the blood related indicator, was significantly lower in moderate/severe group than those in mild group(P<0.05).The expression levels of CD40 L and TGF-β, taken as the qi related indicators, were also significantly lower in moderate/severe group than those in mild group, respectively(P<0.05).Conclusion: The count of PLT might be the biological basis of blood.The expressions of NO, NOS, ET-1 and VEGF-A might be the biological basis of vessel.The expressions of IL-1β, IL-17 A, TNF-α, TGF-β, and CD40 L may be the biological basis of qi.The expressions of CD40 L and TGF-β could reflect the degree of qi deficiency in ITP patients based on the theory of qi and blood.

A Discussion on the Constitution Factors of Thin Endometrium Based on the Theory of Qi and Blood

Thin endometrium has been proven to be a key contributing factor leading to infertility and poor pregnancy outcomes.Increasing the thickness and capacity of thin endometrium seems to be one of the challenging issues in reproductive medicine.The states of qi and blood are closely related to uterine blood circulation.Constitution is regarded as an important basis for determining the incidence as well as distinguishing,preventing,and treating diseases in traditional Chinese medicine.Based on the theory of qi and blood,this paper discusses the constitution factors of thin endometrium and puts forward the prospect of using big data tools to investigate the correlation between qi-blood imbalance constitution and the incidence of thin endometrium,so as to explore new approaches for the prevention and treatment of thin endometrium by regulating qi and blood as well as improving the constitution condition.

DESIGN OF TERNARY CURRENT-MODE CMOS CIRCUITS BASED ON SWITCH-SIGNAL THEORY

By applying switch-signal theory, the interaction between MOS transmission switch-ing transistor and current signal in current-mode CMOS circuits is analyzed, and the theory oftransmission current-switches which is suitable to current-mode CMOS circuits is proposed. Thecircuits, such as ternary full-adder etc., designed by using this theory have simpler circuit struc-tures and correct logic functions. It is confirmed that this theory is efficient in guiding the logicdesign of current-mode CMOS circuits at switch level.

SYNTHESIS OF MULTIVALUED CMOS CIRCUITS WITH MANY VARIABLES BASED ON TRANSMISSION FUNCTION THEORY

Based on transmission function theory,the synthesis technique for multivaluedCMOS circuits is discussed.By comparing the CMOS circuits based on transmission functiontheory with the T gate,it is shown that their action principles are identical.Based on it,thesynthesis method for multivalued CMOS circuits with many variables by using function decom-position is proposed.

Quantum simulation of lattice gauge theories on superconducting circuits:Quantum phase transition and quench dynamics

Recently,quantum simulation of low-dimensional lattice gauge theories(LGTs)has attracted many interests,which may improve our understanding of strongly correlated quantum many-body systems.Here,we propose an implementation to approximate Z;LGT on superconducting quantum circuits,where the effective theory is a mixture of a LGT and a gauge-broken term.By using matrix product state based methods,both the ground state properties and quench dynamics are systematically investigated.With an increase of the transverse(electric)field,the system displays a quantum phase transition from a disordered phase to a translational symmetry breaking phase.In the ordered phase,an approximate Gauss law of the Z;LGT emerges in the ground state.Moreover,to shed light on the experiments,we also study the quench dynamics,where there is a dynamical signature of the spontaneous translational symmetry breaking.The spreading of the single particle of matter degree is diffusive under the weak transverse field,while it is ballistic with small velocity for the strong field.Furthermore,due to the emergent Gauss law under the strong transverse field,the matter degree can also exhibit confinement dynamics which leads to a strong suppression of the nearest-neighbor hopping.Our results pave the way for simulating the LGT on superconducting circuits,including the quantum phase transition and quench dynamics.

A General Method in the Synthesis of Ternary Double Pass-Transistor Circuits

A general method for designing ternary circuits using double pass-transistor logic is investigated. The logical relation of each MOS transistor is formulated by using the transmission operation in order to make effective and practical use of the circuits. A way to generate ternary complementary and dual circuits by applying the complementarity and duality principles is presented. This new static ternary double pass-transistor logic scheme has some favorable properties：the use of standard CMOS process without any modification of the thresholds, a perfectly symmetrical structure,a full logic swing, the maximum possible noise margins, a less complex structure, and no static power consumption. HSPICE simulations using TSMC 0.25μm CMOS technology and a 3V power supply demonstrate the effectiveness of the proposed design.

Effect of Meteorological Factors on Incidence of Tuberculosis:A 15-Year Retrospective Study Based on Chinese Medicine Theory of Five Circuits and Six Qi

ABSTRACT Objective： To analyze the correlations between the incidence of tuberculosis and meteorological factors over the same period and previous periods including 1, 2 and 3 years ago, defined according to the Chinese medicine theory of five circuits （Wu Yun） and six qi, to establish medical-meteorological forecast models for the Beijing area of China. Methods： Data regarding the incidence of tuberculosis between 1990 and 2004 were obtained from the Beijing Center for Disease Control and Prevention, and the data regarding the meteorological factors （including daily average temperatures, wind speeds, precipitations, relative humidities, vapor pressures and low cloud covers） between 1987 and 2004 were collected from the Beijing Meteorological Observatory and analyzed. Descriptive statistics and a back-propagation artificial neural network were adopted to analyze the data. Results： There were significant correlations between the incidence of tuberculosis and the meteorological factors in the corresponding year and previous years. Among these correlations, wind speed was the factor with the strongest influence on tuberculosis （the standardized significance was 100%）. Additionally, all prediction models would successfully established, suggesting the use of a collection of meteorological factors spanning from three years ago to the present is superior to the use of single data. Conclusions： The incidence of tuberculosis in Beijing area is correlated to meteorological factors in the current year and previous years, which verifies the practicality of the theory of five circuits and six qi.

DESIGN OF nMOS QUATERNARY FLIP-FLOPS AND THEIR APPLICATIONS

By using the theory of clipping voltage-switches, two kinds of master/slave nMOS quaternary flip-flops are designed. These flip-flops have the capability of two-input presetting and double-rail complementary outputs. It is shown that these flip-flops are effectively suitable to design nMOS quaternary sequential circuits by designing two examples of hexadecimal up-counter and decimal up-counter.

基于MSPA-MCR-CIRCUIT的山西省运城市景观生态网络构建

山西省运城市位于黄河中下游三省交界处,其景观要素成分复杂,对运城景观生态网络斑块与廊道的研究有利于黄河生态系统稳定性的保护。基于形态空间格局理论(MSPA)确定连通性强的核心斑块,识别核心生态源地,以最小累计阻力模型(MCR)为基础,叠加7种阻力因子构建综合阻力面,根据重力模型划分生态廊道等级。以基于电路理论(CIRCUIT)的Linkage Mapper工具识别生态夹点和障碍点作为生态节点,综合构建源地(面)-廊道(线)-节点(点)的运城市景观生态网络。结果表明:1)运城市核心生态源地有9处,综合重力模型和实际建设需求划分13条重要生态廊道和10条一般生态廊道,识别出关键生态节点17个,一般生态节点34个;2)现有重要生态廊道集中于运城南部,南北方向生态联系较弱,可优先加强贯穿稷山县、新绛县、闻喜县的重要生态廊道建设;3)MSPA模型与电路理论的综合运用可提升景观生态网络构建的科学性和准确性,有利于确定生态修复关键区域,为生态修复项目的布局提供有力支撑。

A Temperature Prediction Model for Oil-immersed Transformer Based on Thermal-circuit Theory

This paper proposed an improved temperature prediction model for oil-immersed transformer.The influences of the environmental temperature and heat-sinking capability changing with temperature were considered.When calculating the heat dissipation from the transformer tank to surroundings,the average oil temperature was selected as the node value in the thermal circuit.The new thermal models will be validated with the delivery experimental data of three transformers: a 220 kV-300 MV.A unit,a 110 kV40 MV.A unit and a 220 kV-75 MV.A unit.Meanwhile,the results from the proposed model were also compared with two methods recommended in the IEC loading guide.

The Changes in the Neck Meridian Test Scores Induced by Self-Administered Acupressure: A Secondary Analysis of Data from a Randomized Controlled Trial of Self-Administered Acupressure

In the neck meridian test, the examinee stretches his or her neck in four directions and rates the intensity of pain and/or symptoms on a four point Likert scale. The four responses are summed to calculate the test score. This study conducted secondary analyses of data from a randomized controlled trial of self-administered acupressure. The study aimed to examine the change of the neck meridian test score induced by self-administered acupressure. The data of 54 (male, n = 34;female, n = 20) students, who were randomly assigned to an intervention group (IG) and a control group (CG), were subjected to secondary analyses. The IG participants were asked to complete a self-administered acupressure intervention for two weeks;the CG participants were not. In the IG, the perceived stress decreased significantly over time, while the neck meridian test score decreased significantly;in contrast, this score increased in the CG. A significant positive correlation was found between the changes in the perceived stress and neck meridian test scores. These results supported validity of the neck meridian test as a tool for assessing perceived stress.

A Study on the Theories of Qi in the Middle Ming Dynasty

The revival of qi theory in the middle Ming dynasty is crucial in the development of Confucianism.In this stage,Luo Qinshun,Wang Yangming,Wang Tingxiang,and LüNan discussed issues such as the relationship between li(principle)and qi(vital energy),the relationship between xing(human nature)and qi,and gongfu(e ort)for the theory of qi. e multifaceted debates between them are relevant to the development of Neo-Confucianism and the issues of Confucianism in the Ming and Qing dynasties,demonstrating the features of mid-Ming Confucian theories of qi.A general survey of the four Confucian scholars’theories of qi,especially the transition from li–qi monism to the xing–qi connection,reveals that how to establish the unity between the universe and human nature in the theories of qi became a central concern of mid-Ming Confucianism.In addition,the gongfu for the theory of qi represented a new level of the holistic development of Ming Confucianism,though it su ered setbacks in its development.

Effect of copper content on the pyrolysis process of organic components in waste printed circuit boards:Based on experimental and quantum chemical DFT simulations

In recent years,scientists have become increasingly concerned in recycling electronic trash,particularly waste printed circuit boards(WPCBs).Previous research has indicated that the presence of Cu impacts the pyrolysis of WPCBs.However,there may be errors in the experimental results,as printed circuit boards(PCBs)with copper and those without copper are produced differently.For this experiment,we blended copper powder with PCB nonmetallic resin powder in various ratios to create the samples.The apparent kinetics and pyrolysis properties of four resin powders with varying copper concentrations were compared using nonisothermal thermogravimetric analysis(TG)and thermal pyrolysis-gas chromatography mass spectrometry(Py-GC/MS).From the perspective of kinetics,the apparent activation energy of the resin powder in the pyrolysis reaction shows a rise(0.1<a<0.2)-stable(0.2<a<0.4)-accelerated increase(0.4<a<0.8)-decrease(0.8<a<0.9)process.After adding copper powder,the apparent activation energy changes more obviously when(0.2<a<0.4).In the early stage of the pyrolysis reaction(0.1<a<0.6),the apparent activation energy is reduced,but when a?0.8,it is much higher than that of the resin sample without copper.Additionally,it is discovered using thermogravimetric analysis and Py-GC/MS that copper shortens the temperature range of the primary pyrolysis reaction and prevents the creation of compounds containing bromine.This inhibition will raise the temperature at which compounds containing bromine first form,and it will keep rising as the copper level rises.The majority of the circuit board molecules have lower bond energies when copper is present,according to calculations performed using the Gaussian09 software,which promotes the pyrolysis reaction.

Novel method of enhancing the key amount for FH systems

Based on the principle of information theory, a novel scheme of unequal-interval frequency-hopping (FH) systems was proposed. For cases of spectrum overlapping systems and non-overlapping systems, the implementation methods were presented and the security performances were discussed theoretically. Firstly, the definitions of absolute and relative key amounts of FH systems, equal-interval and unequal-interval FH systems were given. Then, the absolute key amount and relative key amount were analyzed for equal-interval and unequal-interval FH systems. The results indicated that the absolute key amount had become the key point in improving the security and secrecy of FH systems, especially in today's epoch of highly developed computer science and IC design technology. Theoretical analysis and practical examples showed that the absolute key amount of unequal-interval FH systems was generally over two orders larger than that of equal-interval ones when spectrum overlapping was allowable. Therefore, there was great superiority in enhancing the security and secrecy for the scheme mentioned.

ASYMPTOTIC THEORY FOR THE CIRCUIT ENVELOPE ANALYSIS

Asymptotic theory for the circuit envelope analysis is developed in this paper.A typical feature of circuit envelope analysis is the existence of two significantly distinct timescales:one is the fast timescale of carrier wave,and the other is the slow timescale of modulation signal.We first perform pro forma asymptotic analysis for both the driven and autonomous systems.Then resorting to the Floquet theory of periodic operators,we make a rigorous justification for first-order asymptotic approximations.It turns out that these asymptotic results are valid at least on the slow timescale.To speed up the computation of asymptotic approximations,we propose a periodization technique,which renders the possibility of utilizing the NUFFT algorithm.Numerical experiments are presented,and the results validate the theoretical findings.

Transmission upper limit of band-pass double-layer FSS and method of transmission performance improvement

The transmission upper limit of a double-layer frequency selective surface （FSS） with two infinitely thin metal arrays is pre- sented based on the study of the general equivalent transmission line model of a double-layer FSS. Results of theoretical analyses, numerical simulations and experiments show that this transmis- sion upper limit is independent of the array and the element, which indicates that it is impossible to achieve a transmission upper limit higher than this one under a given incident and dielectric- supporting condition by the design of the periodic array. Both the applicable condition and the possible application of the transmis- sion upper limit are discussed. The results show that the transmis- sion upper limit not only has a good reachability, but also provides a key to effectively improve the transmission performance of a double-layer FSS or more complex frequency selective structures.