In this contribution results from different disciplines of science were compared to show their intimate interweaving with each other having in common the golden ratio <i><span style="font-family:Verdana;...In this contribution results from different disciplines of science were compared to show their intimate interweaving with each other having in common the golden ratio <i><span style="font-family:Verdana;">φ</span></i><span style="font-family:Verdana;"> respectively its fifth power </span><i><span style="font-family:Verdana;">φ</span></i><sup><span style="font-family:Verdana;">5</span></sup><span style="font-family:Verdana;">. The research fields cover model calculations of statistical physics associated with phase transitions, the quantum probability of two particles, new physics of everything suggested by the information relativity theory (</span><i><span style="font-family:Verdana;">IRT</span></i><span style="font-family:Verdana;">) including explanations of cosmological relevance, the </span><i><span style="font-family:Verdana;">ε</span></i><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">-</span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">infinity theory, superconductivity, and the </span><i><span style="font-family:Verdana;">Tammes</span></i><span style="font-family:Verdana;"> problem of the largest diameter of </span><i><span style="font-family:Verdana;">N</span></i><span style="font-family:Verdana;"> non-overlapping circles on the surface of a sphere with its connection to viral morphology and crystallography. Finally, </span><i><span style="font-family:Verdana;">Fibo</span><span style="font-family:Verdana;">nacci</span></i><span style="font-family:Verdana;"> anyons proposed for topological quantum</span><span style="font-family:Verdana;"> computation (</span><i><span style="font-family:Verdana;">TQC</span></i><span style="font-family:Verdana;">) were briefly described in comparison to the recently formulated reverse </span><i><span style="font-family:Verdana;">Fibonacci</span></i><span style="font-family:Verdana;"> approach using the </span><span style="font-family:Verdana;"><em>Jani</em></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="white-space:nowrap;"><em>č</em></span><em>ko</em></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> number sequence. An architecture applicable for a quantum computer is proposed consisting of 13-step twisted microtubules similar to tubulin microtubules of living matter. Most topics point to the omnipresence of the golden mean as the numerical dominator of our world.</span></span></span>展开更多
Mean platelet volume (MPV) is an early marker ofplatelet activation. Larger platelets, compared to small ones, increase platelet adhesion and aggregation, and present a higher thrombotic activity. Some studies have ...Mean platelet volume (MPV) is an early marker ofplatelet activation. Larger platelets, compared to small ones, increase platelet adhesion and aggregation, and present a higher thrombotic activity. Some studies have explored the association between MPV and the morbidity of portal vein thrombosis (PVT). The aim of this study was to evaluate the predictive effect of MPV in patients with PVT by a meta-analysis. We searched Pubmed, Web of Science, SCOPUS, OVID, CNKI and CBMD from database inception to September 13, 2017. Seven studies in accordance with selection criteria were included. The extraction of basic data was independently conducted by two reviewers. The mean difference in MPV between PVT patients and controls were pooled with weighted mean difference (WMD) and 95% confidence interval of 0.88 fl (95% CI: 0.61-1.15). A random-effect model was chosen for an obvious heterogeneity in the pooling (Chi-square=27.12, df=6, P〈0.0001, F=77.9%). The sources of heterogeneity were from the difference of primary disease of participants and portal vein diameter. Taken together, our results reveal that MPV is a predictive indicator in patients with PVT.展开更多
We investigate the effect of interaction, temperature, and anisotropic parameter on the quantum phase transitions in an anisotropic square-octagon lattice with fermions under the framework of the single band Hubbard m...We investigate the effect of interaction, temperature, and anisotropic parameter on the quantum phase transitions in an anisotropic square-octagon lattice with fermions under the framework of the single band Hubbard model through using the combination of cellular dynamical mean field theory and a continuous time Monte Carlo algorithm. The competition between interaction and temperature shows that with the increase of the anisotropic parameter, the critical on-site repulsive interaction for the metal-insulator transition increases for fixed temperature. The interaction-anisotropic parameter phase diagram reveals that with the decrease of temperature, the critical anisotropic parameter for the Mott transition will increase for fixed interaction cases.展开更多
In the present paper, we have studied the effect of Ge addition on the physical properties of Se-Sn-Pb chalcogenide ma- terial. The necessary physical parameters which have important role in determining the structure ...In the present paper, we have studied the effect of Ge addition on the physical properties of Se-Sn-Pb chalcogenide ma- terial. The necessary physical parameters which have important role in determining the structure and strength of the material viz. constraints, coordination number etc. have been calculated. The increasing trend has been found in cohesive energy, heat of atomization and mean bond energy. The glass transition has been studied using the Tichy-Ticha and Lankhorst approaches, which also increases with the increasing Ge contents. The increase in these physical parameters is due to the increasing covalent character in the material.展开更多
We used a combined quantum mechanics and molecular mechanics (QM/MM) method to investigate the solvent effects and potential of mean force of the CH3F+CN- reaction in water. Comparing to gas phase, the water soluti...We used a combined quantum mechanics and molecular mechanics (QM/MM) method to investigate the solvent effects and potential of mean force of the CH3F+CN- reaction in water. Comparing to gas phase, the water solution substantially affects the structures of the stationary points along the reaction path. We quantitatively obtained the solvent effects' contributions to the reaction: 1.7 kcal/mol to the activation barrier and -26.0 kcal/mol to the reaction free energy. The potential mean of force calculated with the density functional theory/MM theory has a barrier height at 19.7 kcal/mol, consistent with the experimental result at 23.0 kcal/mol; the calculated reaction free energy at -43.5 kcal/mol is also consistent with the one estimated based on the gas-phase data at -39.7 kcal/mol.展开更多
The quaternary chalcogenide glass Te9Se72Ge19-xSbx (x = 8, 9, 10, 11, 12) has been prepared by the melt quench technique. The material fragility increases due to decrease in degree of cross linking in glass matrix as ...The quaternary chalcogenide glass Te9Se72Ge19-xSbx (x = 8, 9, 10, 11, 12) has been prepared by the melt quench technique. The material fragility increases due to decrease in degree of cross linking in glass matrix as the Sb content increases. The heat of atomization decreases due to lower value of heat of atomization of antimony. The glass transition temperature is calculated by Tichy-Ticha and Lankhorst approaches. The glass seems to have high value of glass transition temperature as per theoretical calculations and is monotonically decreasing with increasing Sb content because increasing concentration of Sb reduces the cohesive energy and mean bond energy of the material.展开更多
BACKGROUND Preoperative portal vein embolization(PVE)is a widely used strategy to enable major hepatectomy in patients with insufficient liver remnant.PVE induces hypertrophy of the future liver remnant(FLR)and a shif...BACKGROUND Preoperative portal vein embolization(PVE)is a widely used strategy to enable major hepatectomy in patients with insufficient liver remnant.PVE induces hypertrophy of the future liver remnant(FLR)and a shift of the functional reserve to the FLR.However,whether the increase of the FLR volume(FLRV)corresponds to the functional transition after PVE remains unclear.AIM To investigate the sequential relationship between the increase in FLRV and functional transition after preoperative PVE using 3-dimensional(3D)computed tomography(CT)and 99mTc-galactosyl-human serum albumin(99mTc-GSA)singlephoton emission computed tomography(SPECT)fusion images.METHODS Thirty-three patients who underwent major hepatectomy following PVE at the Department of Gastroenterological Surgery I,Hokkaido University Hospital between October 2013 and March 2018 were enrolled.Three-phase dynamic multidetector CT and 99mTc-GSA SPECT scintigraphy were performed at pre-PVE,and at 1 and 2 wk after PVE;3D 99mTc-GSA SPECT CT-fused images were constructed from the Digital Imaging and Communications in Medicine data using 3D image analysis system.Functional FLRV(FFLRV)was defined as the total liver volume×(FLR volume counts/total liver volume counts)on the 3D 99m Tc-GSA SPECT CT-fused images.The calculated FFLRV was compared with FLRV.RESULTS FFLRV increased by a significantly larger extent than FLRV at 1 and 2 wk after PVE(P<0.01).The increase in FFLRV and FLRV was 55.1%±41.6%and 26.7%±17.8%(P<0.001),respectively,at 1 wk after PVE,and 64.2%±33.3%and 36.8%±18.9%(P<0.001),respectively,at 2 wk after PVE.In 3 of the 33 patients,FFLRV levels decreased below FLRV at 2 wk.One of the three patients showed rapidly progressive fatty changes in FLR.The biopsy at 4 wk after PVE showed macroand micro-vesicular steatosis of more than 40%,which improved to 10%.Radical resection was performed at 13 wk after PVE.The patient recovered uneventfully without any symptoms of pos-toperative liver failure.CONCLUSION The functional transition lagged behind the increase in FLRV after PVE in some cases.Evaluating both volume and function is needed to determine the optimal timing of hepatectomy after PVE.展开更多
Some in vitro experiments have shown that erythropoietin (EPO) increases resistance to apoptosis and facilitates neuronal survival follow- ing cerebral ischemia. However, results from in vivo studies are rarely repo...Some in vitro experiments have shown that erythropoietin (EPO) increases resistance to apoptosis and facilitates neuronal survival follow- ing cerebral ischemia. However, results from in vivo studies are rarely reported. Perfusion-weighted imaging (PWI) and diffusion-weighted imaging (DWI) have been applied successfully to distinguish acute cerebral ischemic necrosis and penumbra in living animals; therefore, we hypothesized that PWI and DWI could be used to provide imaging evidence in vivo for the conclusion that EPO could reduce apoptosis in brain areas injured by cerebral ischemia/reperfusion. To validate this hypothesis, we established a rat model of focal cerebral ischemia/ reperfusion injury, and treated with intra-cerebroventricular injection of EPO (5,000 U/kg) 20 minutes before injury. Brain tissue in the ischemic injury zone was sampled using MRI-guided localization. The relative area of abnormal tissue, changes in PWI and DWI in the ischemic injury zone, and the number of apoptotic cells based on TdT-mediated dUTP-biotin nick end-labeling (TUNEL) were assessed. Our findings demonstrate that EPO reduces the relative area of abnormally high signal in PWI and DWI, increases cerebral blood volume, and decreases the number of apoptotic cells positive for TUNEL in the area injured by cerebral ischemia/reperfusion. The experiment pro- vides imaging evidence in vivo for EPO treating cerebral ischemia/reperfusion injury.展开更多
文摘In this contribution results from different disciplines of science were compared to show their intimate interweaving with each other having in common the golden ratio <i><span style="font-family:Verdana;">φ</span></i><span style="font-family:Verdana;"> respectively its fifth power </span><i><span style="font-family:Verdana;">φ</span></i><sup><span style="font-family:Verdana;">5</span></sup><span style="font-family:Verdana;">. The research fields cover model calculations of statistical physics associated with phase transitions, the quantum probability of two particles, new physics of everything suggested by the information relativity theory (</span><i><span style="font-family:Verdana;">IRT</span></i><span style="font-family:Verdana;">) including explanations of cosmological relevance, the </span><i><span style="font-family:Verdana;">ε</span></i><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">-</span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">infinity theory, superconductivity, and the </span><i><span style="font-family:Verdana;">Tammes</span></i><span style="font-family:Verdana;"> problem of the largest diameter of </span><i><span style="font-family:Verdana;">N</span></i><span style="font-family:Verdana;"> non-overlapping circles on the surface of a sphere with its connection to viral morphology and crystallography. Finally, </span><i><span style="font-family:Verdana;">Fibo</span><span style="font-family:Verdana;">nacci</span></i><span style="font-family:Verdana;"> anyons proposed for topological quantum</span><span style="font-family:Verdana;"> computation (</span><i><span style="font-family:Verdana;">TQC</span></i><span style="font-family:Verdana;">) were briefly described in comparison to the recently formulated reverse </span><i><span style="font-family:Verdana;">Fibonacci</span></i><span style="font-family:Verdana;"> approach using the </span><span style="font-family:Verdana;"><em>Jani</em></span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="white-space:nowrap;"><em>č</em></span><em>ko</em></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> number sequence. An architecture applicable for a quantum computer is proposed consisting of 13-step twisted microtubules similar to tubulin microtubules of living matter. Most topics point to the omnipresence of the golden mean as the numerical dominator of our world.</span></span></span>
基金This work was supported by the National Natural Science Foundation of China (No. 81500109).
文摘Mean platelet volume (MPV) is an early marker ofplatelet activation. Larger platelets, compared to small ones, increase platelet adhesion and aggregation, and present a higher thrombotic activity. Some studies have explored the association between MPV and the morbidity of portal vein thrombosis (PVT). The aim of this study was to evaluate the predictive effect of MPV in patients with PVT by a meta-analysis. We searched Pubmed, Web of Science, SCOPUS, OVID, CNKI and CBMD from database inception to September 13, 2017. Seven studies in accordance with selection criteria were included. The extraction of basic data was independently conducted by two reviewers. The mean difference in MPV between PVT patients and controls were pooled with weighted mean difference (WMD) and 95% confidence interval of 0.88 fl (95% CI: 0.61-1.15). A random-effect model was chosen for an obvious heterogeneity in the pooling (Chi-square=27.12, df=6, P〈0.0001, F=77.9%). The sources of heterogeneity were from the difference of primary disease of participants and portal vein diameter. Taken together, our results reveal that MPV is a predictive indicator in patients with PVT.
基金supported by the National Natural Science Foundation of China(Grant Nos.11174169,11234007,and 51471093)
文摘We investigate the effect of interaction, temperature, and anisotropic parameter on the quantum phase transitions in an anisotropic square-octagon lattice with fermions under the framework of the single band Hubbard model through using the combination of cellular dynamical mean field theory and a continuous time Monte Carlo algorithm. The competition between interaction and temperature shows that with the increase of the anisotropic parameter, the critical on-site repulsive interaction for the metal-insulator transition increases for fixed temperature. The interaction-anisotropic parameter phase diagram reveals that with the decrease of temperature, the critical anisotropic parameter for the Mott transition will increase for fixed interaction cases.
文摘In the present paper, we have studied the effect of Ge addition on the physical properties of Se-Sn-Pb chalcogenide ma- terial. The necessary physical parameters which have important role in determining the structure and strength of the material viz. constraints, coordination number etc. have been calculated. The increasing trend has been found in cohesive energy, heat of atomization and mean bond energy. The glass transition has been studied using the Tichy-Ticha and Lankhorst approaches, which also increases with the increasing Ge contents. The increase in these physical parameters is due to the increasing covalent character in the material.
基金Project supported by the National Natural Science Foundation of China(Grant No.11774206)Taishan Scholarship Fund from Shandong Province,China
文摘We used a combined quantum mechanics and molecular mechanics (QM/MM) method to investigate the solvent effects and potential of mean force of the CH3F+CN- reaction in water. Comparing to gas phase, the water solution substantially affects the structures of the stationary points along the reaction path. We quantitatively obtained the solvent effects' contributions to the reaction: 1.7 kcal/mol to the activation barrier and -26.0 kcal/mol to the reaction free energy. The potential mean of force calculated with the density functional theory/MM theory has a barrier height at 19.7 kcal/mol, consistent with the experimental result at 23.0 kcal/mol; the calculated reaction free energy at -43.5 kcal/mol is also consistent with the one estimated based on the gas-phase data at -39.7 kcal/mol.
文摘The quaternary chalcogenide glass Te9Se72Ge19-xSbx (x = 8, 9, 10, 11, 12) has been prepared by the melt quench technique. The material fragility increases due to decrease in degree of cross linking in glass matrix as the Sb content increases. The heat of atomization decreases due to lower value of heat of atomization of antimony. The glass transition temperature is calculated by Tichy-Ticha and Lankhorst approaches. The glass seems to have high value of glass transition temperature as per theoretical calculations and is monotonically decreasing with increasing Sb content because increasing concentration of Sb reduces the cohesive energy and mean bond energy of the material.
文摘BACKGROUND Preoperative portal vein embolization(PVE)is a widely used strategy to enable major hepatectomy in patients with insufficient liver remnant.PVE induces hypertrophy of the future liver remnant(FLR)and a shift of the functional reserve to the FLR.However,whether the increase of the FLR volume(FLRV)corresponds to the functional transition after PVE remains unclear.AIM To investigate the sequential relationship between the increase in FLRV and functional transition after preoperative PVE using 3-dimensional(3D)computed tomography(CT)and 99mTc-galactosyl-human serum albumin(99mTc-GSA)singlephoton emission computed tomography(SPECT)fusion images.METHODS Thirty-three patients who underwent major hepatectomy following PVE at the Department of Gastroenterological Surgery I,Hokkaido University Hospital between October 2013 and March 2018 were enrolled.Three-phase dynamic multidetector CT and 99mTc-GSA SPECT scintigraphy were performed at pre-PVE,and at 1 and 2 wk after PVE;3D 99mTc-GSA SPECT CT-fused images were constructed from the Digital Imaging and Communications in Medicine data using 3D image analysis system.Functional FLRV(FFLRV)was defined as the total liver volume×(FLR volume counts/total liver volume counts)on the 3D 99m Tc-GSA SPECT CT-fused images.The calculated FFLRV was compared with FLRV.RESULTS FFLRV increased by a significantly larger extent than FLRV at 1 and 2 wk after PVE(P<0.01).The increase in FFLRV and FLRV was 55.1%±41.6%and 26.7%±17.8%(P<0.001),respectively,at 1 wk after PVE,and 64.2%±33.3%and 36.8%±18.9%(P<0.001),respectively,at 2 wk after PVE.In 3 of the 33 patients,FFLRV levels decreased below FLRV at 2 wk.One of the three patients showed rapidly progressive fatty changes in FLR.The biopsy at 4 wk after PVE showed macroand micro-vesicular steatosis of more than 40%,which improved to 10%.Radical resection was performed at 13 wk after PVE.The patient recovered uneventfully without any symptoms of pos-toperative liver failure.CONCLUSION The functional transition lagged behind the increase in FLRV after PVE in some cases.Evaluating both volume and function is needed to determine the optimal timing of hepatectomy after PVE.
文摘Some in vitro experiments have shown that erythropoietin (EPO) increases resistance to apoptosis and facilitates neuronal survival follow- ing cerebral ischemia. However, results from in vivo studies are rarely reported. Perfusion-weighted imaging (PWI) and diffusion-weighted imaging (DWI) have been applied successfully to distinguish acute cerebral ischemic necrosis and penumbra in living animals; therefore, we hypothesized that PWI and DWI could be used to provide imaging evidence in vivo for the conclusion that EPO could reduce apoptosis in brain areas injured by cerebral ischemia/reperfusion. To validate this hypothesis, we established a rat model of focal cerebral ischemia/ reperfusion injury, and treated with intra-cerebroventricular injection of EPO (5,000 U/kg) 20 minutes before injury. Brain tissue in the ischemic injury zone was sampled using MRI-guided localization. The relative area of abnormal tissue, changes in PWI and DWI in the ischemic injury zone, and the number of apoptotic cells based on TdT-mediated dUTP-biotin nick end-labeling (TUNEL) were assessed. Our findings demonstrate that EPO reduces the relative area of abnormally high signal in PWI and DWI, increases cerebral blood volume, and decreases the number of apoptotic cells positive for TUNEL in the area injured by cerebral ischemia/reperfusion. The experiment pro- vides imaging evidence in vivo for EPO treating cerebral ischemia/reperfusion injury.