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Experiencing the Abject Female Body and Writing the Female Self:Body Narrative of In the Heart of the Country
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作者 SHI Ju-hong HAO Wen-xuan 《Journal of Literature and Art Studies》 2024年第6期395-403,共9页
In the Heart of the Country,the second novel by J.M.Coetzee,has been traditionally read as a disembodied writing that focuses on the problem of writing per se instead of the reality.This paper contends that the work i... In the Heart of the Country,the second novel by J.M.Coetzee,has been traditionally read as a disembodied writing that focuses on the problem of writing per se instead of the reality.This paper contends that the work is actually a body narrative that explores the visceral pain suffered by Magda whose infertile body impedes her being a qualified subject.As the heroine in a postcolonial novel,Magda is not just a body that is restricted and constructed by the politics of the body,but also a thinking and writing body that consciously questions and resists the gendered bodily norms under whose yardstick her subjecthood is barred.Written in the metafictional manner,Magda’s narrative of the body is not just a record of her corporeal experience,but also a self-conscious negotiation with,and challenge of,the bodily norms under whose yardstick her body has been debased or,in terms of Judith Butler,abjected.Taking her female bodily experience as the starting point,Magda writes a feminine text that values passion,fluidity and non-linearity to disrupt the patriarchal discourse underpinned with logical reasoning.The feminine body narrative endeavors to achieve a new way of communication through which a reciprocal cross race/gender relationship might be established. 展开更多
关键词 J.M.Coetzee In the heart of the Country abject female body body narrative feminine text
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Association of Congenital Heart Defects (CHD) with Factors Related to Maternal Health and Pregnancy in Newborns in Puerto Rico
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作者 Yamixa Delgado Caliani Gaytan +3 位作者 Naydi Perez Eric Miranda Bryan Colón Morales Mónica Santos 《Congenital Heart Disease》 SCIE 2024年第1期19-31,共13页
Background:Given the pervasive issues of obesity and diabetes both in Puerto Rico and the broader United States,there is a compelling need to investigate the intricate interplay among body mass index(BMI),pregesta-tio... Background:Given the pervasive issues of obesity and diabetes both in Puerto Rico and the broader United States,there is a compelling need to investigate the intricate interplay among body mass index(BMI),pregesta-tional,and gestational maternal diabetes,and their potential impact on the occurrence of congenital heart defects(CHD)during neonatal development.Methods:Using the comprehensive System of Vigilance and Surveillance of Congenital Defects in Puerto Rico,we conducted a focused analysis on neonates diagnosed with CHD between 2016 and 2020.Our assessment encompassed a range of variables,including maternal age,gestational age,BMI,pregestational diabetes,gestational diabetes,hypertension,history of abortion,and presence of preeclampsia.Results:A cohort of 673 patients was included in our study.The average maternal age was 26 years,within a range of 22 to 32 years.The mean gestational age measured 39 weeks,with a median span of 38 to 39 weeks.Of the 673 patients,274(41%)mothers gave birth to neonates diagnosed with CHD.Within this group,22 cases were linked to pre-gestational diabetes,while 202 were not;20 instances were associated with gestational diabetes,compared to 200 without;and 148 cases exhibited an overweight or obese BMI,whereas 126 displayed a normal BMI.Conclusion:We identified a statistically significant correlation between pre-gestational diabetes mellitus and the occurrence of CHD.However,our analysis did not show a statistically significant association between maternal BMI and the likelihood of CHD.These results may aid in developing effective strategies to prevent and manage CHD in neonates. 展开更多
关键词 Congenital heart defects(CHD) obesisty maternal health DIABETES body mass index(BMI)
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Relationship Between Serum Leptin Concentration and Lipids & Body Mass Index in Patients With Chronic Congestive Heart Failure 被引量:1
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作者 李刚 严清波 魏良明 《South China Journal of Cardiology》 CAS 2006年第1期40-43,9,共5页
Objectives To investigate the relationship of serum leptin concentration with the lipids and body mass index (BMI) in patients with chronic congestive heart failure(CHF). Methods The serum concentration of leptin ... Objectives To investigate the relationship of serum leptin concentration with the lipids and body mass index (BMI) in patients with chronic congestive heart failure(CHF). Methods The serum concentration of leptin in 39 patients with CHF (14 in cardiac function class Ⅱ , 21 in class Ⅲ, 4 in classⅣ , NYHA) and in 46 patients with cardiac function class Ⅰ (NYHA) were assessed by radioimmunoassay. Results The serum concentration of leptin were 9.018±4.519 μg/l in CHF group (cardiac function class Ⅱ 11.492±5.649 μg/l, class Ⅲ 7.763±3.321 μg/l, class Ⅳ 6.100±2.657 μg/l); 11.674± 6.911 μg/l in class Ⅰ group. The serum concentrations of leptin were significantly lower in CHF group, as compared with class Ⅰ group (P〈 0.05). Moreover, the decrease of serum leptin concentration was significantly correlated with the decreased serum concentrations of total cholesterol, triglyceride, body mass index and left ventricular ejection fraction in CHF group, respectively (P 〈 0.05). Conclusions The significance of the decrease in serum leptin in CHF patients needs further study. 展开更多
关键词 Congestive heart failure Leptin Serum lipids body mass index
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A Study into Blood Flow, Heart Rate Variability, and Body Surface Temperature While Listening to Music 被引量:1
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作者 Kenichi Itao Makoto Komazawa Hiroyuki Kobayashi 《Health》 2018年第2期181-188,共8页
In this study we examined the relaxing effects of listening to music on a total of 12 women aged from their 20s to their 40s by measuring their blood flow, heart rate variability, and their body surface temperature. A... In this study we examined the relaxing effects of listening to music on a total of 12 women aged from their 20s to their 40s by measuring their blood flow, heart rate variability, and their body surface temperature. As a result, We found that there was a tendency for the volume of blood flow to the fingertips to significantly increase when listening to classical music, but there was a variety of changes in blood flow between each age group for healing music and J-Pop music. When measuring heart rate it was found that the LF/HF value, which is an index for the autonomic nervous system which shows tension and stress, fell significantly when listening to each type of music. Lastly, there was a trend for body surface temperature to rise when listening to classical or healing music, a rise which was particularly significant when listening to healing music. This study shows that a relaxing effect can be expected for all indices when listening to classical music. However, for healing music and J-Pop, personal musical preferences seemed to have an effect and the results were varied. 展开更多
关键词 Music BLOOD Flow heart Rate Variability AUTONOMIC Nervous System body Surface TEMPERATURE
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Factors influencing the use of heart rate variability for evaluating autonomic nervous function in mind-body research
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作者 Shin Lin Zhong-Yuan Shen Timothy Ross 《实用心电学杂志》 2017年第2期84-90,共7页
关键词 heart rate variability respiratory SINUS ARRHYTHMIA AUTONOMIC nervous function MIND body RESEARCH
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STUDY AND APPLICATION ABOUT COMPUTED SYSTEM FOR EXTERNAL CARDIAC MASSAGE, MONITOR OF HEART AND BODY TEMPERATURE
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作者 LIU Mingshun WU Wensheng +1 位作者 MENG Fanhang ZHU Shouzeng 《现代电生理学杂志》 2006年第1期26-27,共2页
Objective:To make and study computed system for external cardiac massage,monitor of heart and body temperature and observe its clinical effect.Method:The system was made and applied.Result:The effect of system was obv... Objective:To make and study computed system for external cardiac massage,monitor of heart and body temperature and observe its clinical effect.Method:The system was made and applied.Result:The effect of system was obvious.Conclusion: The system was an effective clinical equipment in treatment of patient with cardiac arrest. 展开更多
关键词 computed system for external cardiac massage monitor of heart and body temperature STUDY clinical application
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Effect of Body Mass Index on All-cause Mortality and Incidence of Cardiovascular Diseases─Report for Meta-Analysis of Prospective Studies on Optimal Cut-off Points of Body Mass Index in Chinese Adults 被引量:58
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作者 ZHOU BEI-FAN 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2002年第3期245-252,共8页
Objective To verify the optimal cut-off points for overweight and obesity in Chinese adults based on the relationship of baseline body mass index (BMI) to all-cause mortality, and incidence of cardiovascular diseases... Objective To verify the optimal cut-off points for overweight and obesity in Chinese adults based on the relationship of baseline body mass index (BMI) to all-cause mortality, and incidence of cardiovascular diseases from pooled data of Chinese cohorts. Methods The prospective study data of existing cohort studies in China were collected, and the age-adjusted all-cause mortality stratified by BMI were estimated. The similar analysis was repeated after excluding deaths within the first three years of follow-up and after excluding smokers. The incidence of age-adjusted coronary heart disease (CHD) and stroke stratified by BMI were also analyzed. Multiple Cox regression coefficients of BMI for the incidence of CHD and stroke after controlling other risk factors were pooled utilizing the methods of weighting by inverse of variance to reveal whether BMI had independent effect and its strength on the incidence of CHD and stroke. Results The data of 4 cohorts including 76 227 persons, with 745 346 person-years of follow-up were collected and analyzed. The age-adjusted all-cause mortality stratified by BMI showed a U-shaped curve, even after excluding deaths within the first three years of follow-up and excluding smokers. Age-adjusted all-cause mortality increased when BMI was lower than 18.5 and higher than 28. The incidence of CHD and stroke, especially ishemic stroke increased with increasing BMI, this was consistent with parallel increasing of risk factors. Cox regression analysis showed that BMI was an independent risk factor for both CHD and stroke. Each amount of 2 kg/m2 increase in baseline BMI might cause 15.4%, 6.1% and 18.8 % increase in relative risk of CHD, total stroke and ischemic stroke. Reduction of BMI to under 24 might prevent the incidence of CHD by 11% and that of stroke by 15 % for men, and 22 % of both diseases for women. Conclusion BMI ≤18.5, 24-27.9 and ≥28 (kg/m2) is the appropriate cut-off points for underweight, overweight and obesity in Chinese adults. 展开更多
关键词 body mass index (BMI) All-cause mortality Coronary heart disease STROKE
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An investigation using high-precision CCD laser displacement sensor to measure body surface motion induced by heartbeat 被引量:1
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作者 Satoshi Suzuki Takemi Matsui +1 位作者 Takafumi Asao Kentaro Kotani 《Journal of Biomedical Science and Engineering》 2012年第11期672-677,共6页
The aim of this study was to measure the motion of the body surface induced by heartbeat by using a high-precision laser sensor in order to provide a reference for other research on medical remote sensing techniques t... The aim of this study was to measure the motion of the body surface induced by heartbeat by using a high-precision laser sensor in order to provide a reference for other research on medical remote sensing techniques that are unconstrained and non-contact. Body surface motions at some points on the chest and on the dorsal region were measured for eight men with a laser displacement sensor. For comparison, an electrocardiograph was also used to monitor the heartbeat. As a result, we confirmed cyclic motion of about 0.1 mm in amplitude everywhere on the body surface, not only from the front of the body but also from the back and the neck. In contrast, which part on the body was most suitable for measurement had to be taken into account because a difference in motion amplitudes was observed in different parts on the body. The amplitude of the motions also depended on the conditions of the body surface as well as underneath the skin. These results show the possibility of acquiring information about heartbeats from anywhere on the body by using an unconscious sensing technique, and the potential for the technique to monitor the condition of the body and personal physical characteristics. 展开更多
关键词 UNCONSTRAINED Sensing heart Rate body Surface MOTION
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Studies of anthropometric indicators and their relationship with metabolic variables
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作者 Antonia Dalla Pria Bankoff Leandro Calixto Zago 《Open Journal of Preventive Medicine》 2014年第2期64-68,共5页
The purpose of this work is to identify in the anthropometrical indicators used here in this study the percentage of body fat, the body mass index (BMI) and the waist-hip ratio (WHR), which present a correlation with ... The purpose of this work is to identify in the anthropometrical indicators used here in this study the percentage of body fat, the body mass index (BMI) and the waist-hip ratio (WHR), which present a correlation with the metabolic variables of heart rate, blood pressure (systolic and diastolic) and double product. A population of 69 subjects averaging 41.7 ± 6.6 years old had their data registered by applying the Bruce Protocol modified to calculate metabolic variables;to obtain the percentage of fat, the formula of Petroski was used. The data collected received statistical treatment by the “Statistical 5.0” program with correlation being made by the calculation of the simple coefficient of Pearson “r” by means of a statistical significance test (p < 0.05). In the results, heart rate appeared to be correlated essentially with the intensity of force, associating itself with the percentage of fat and the BMI. Blood pressure presented a good correlation with the BMI, principally in the female group. In the male group, the anthropometrical indicator that had major associations with blood pressure was the WHR, showing an association between the pattern of male body fat distribution (android) and blood pressure. The double-product had a major correlation with the BMI;however, this variable really reflects the work of the myocardium since the BMI is the only indicator used here that includes lean mass in its values. The time spent on the treadmill was correlated in a negative way only with the percentage of fat;in other words, the greater the percentage, the lesser time spent on the treadmill. 展开更多
关键词 ANTHROPOMETRY body FAT heart Rate Blood Pressure
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Body-temperature circadian rhythm in 67 patients after heart valve replacement surgery secondary to valvular heart disease
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作者 Xiao-Ying Jiang Cong Wang 《International Journal of Nursing Sciences》 2014年第1期64-68,共5页
Purpose:Patient body temperature was monitored after cardiac valve replacement,in order to explore the characteristics of body-temperature circadian rhythm and the factors influencing that rhythm.Methods:A cohort of 6... Purpose:Patient body temperature was monitored after cardiac valve replacement,in order to explore the characteristics of body-temperature circadian rhythm and the factors influencing that rhythm.Methods:A cohort of 67 patients who received cardiac valve replacement in a Fuzhou,Fujian province,China,general hospital underwent temperature measurements and analysis(by cosine curve)of their body-temperature circadian rhythm.A biological rhythm model was established through principal component analysis and evaluation of biological rhythm features.Multiple circadian parameters were included through linear regression analysis.Results:Patients’temperature after cardiac valve replacement exhibited circadian characteristics(p<0.05),among which the scores of temperature mesor,amplitude,and acrophase were respectively(37.610.08),(0.100.09),and33(e355,e119).Body-temperature rhythms were influenced by both gender and cardiopulmonary bypass time(p<0.05).Conclusion:Although some patients’circadian characteristics disappeared after cardiac valve replacement,circadian rhythms remained intact for most patients.Measures that were found to mitigate body-temperature circadian rhythm disruption included building a natural rhythm of light/darkness and decreasing cardiopulmonary bypass time. 展开更多
关键词 body temperature Circadian rhythm heart valve replacement Rheumatic heart disease
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Evaluation of global cardiac systolic performance and diastolic filling in central hypovolumia by lower body negative pressure with Doppler echocardiography
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作者 Baomin Liu Xiaolin Niu +3 位作者 Benyu Jiang Mike Seddon Keren McNeil Philip Chowienczyk 《Journal of Nanjing Medical University》 2007年第4期227-232,共6页
Objective :To overall evaluate the change of global cardiac systolic performance and diastolic filling in hypovoleamia by LBNP, Methods:10 healthy male subjects were placed in a standard LBNP chamber. Baseline haemo... Objective :To overall evaluate the change of global cardiac systolic performance and diastolic filling in hypovoleamia by LBNP, Methods:10 healthy male subjects were placed in a standard LBNP chamber. Baseline haemodynamic and echocardiographic measurements were made after a period of least 10 min resting supine within the chamber. Pressure was then decreased to -10,-20 and -30 mmHg, with each pressure maintained for 15 rain. The indices of four transvalvular and SVC flow were measured using Doppler echocardiography. Results :The results showed that S wave, Re wave ,and VTI of SVC progressively decreased with increasing LBNP. At -30 mmHg stage, S wave decreased by 35.4 % (change of 0.21±0.03 m/s, P 〈 0.001). This reduction in pre-load Was associated with a progressive decrease in SV(by 21.5 ± 4.5 ml at -30 mmHg,P 〈 0.001 ), decrease in CO(by 1.2 ± 0.2 L min^-1 at -30 mmHg LBNP,P 〈 0.001 ). The diastolic filling of mitral and tricuspid flow also reduced significantly. At -30 mmHg stage, the E wave of MVF and TVF decreased 31% and 32% respectively (change of 0.23 ± 0.05 m/s,P 〈 0.001 and 0.18 ± 0.01 m/s,P 〈 0.001). VTI of MVF and TVF decreased 27% and 27.7% respectively(change of 5.55 ± 1.41cm,P 〈 0.01 and 4.25 ± 0.44 cm,P 〈 0.01). A wave of both sides did not change significantly. Conclusion:Doppler indices changes in different LBNP stage can roughly reflect the degree of hypovoleamia caused by blood volume redistribution. The indices of Doppler echocardiography are more sensitive than traditional physiological indexes in evaluating cardiovascular responses of LBNP. Echocardiography techniques overall can evaluate the global cardiac function including systolic performance and diastolic filling. 展开更多
关键词 function heart ECHOCARDIOGRAPHY lower body negative pressure
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宽体探测器CT血管造影与超声心动图对小儿先天性心脏病的诊断效能
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作者 祁冬 李娟 +3 位作者 孙景巍 董楠 贾媛 沈艳 《联勤军事医学》 CAS 2024年第1期22-25,35,共5页
目的探讨宽体探测器CT血管造影(computer tomography angiography,CTA)与超声心动图(ultrasound cardiogram,UCG)在小儿先天性心脏病(congenital heart disease,CHD)的诊断效能。方法回顾性分析2019-08/2023-09月作者医院收治的65例疑似... 目的探讨宽体探测器CT血管造影(computer tomography angiography,CTA)与超声心动图(ultrasound cardiogram,UCG)在小儿先天性心脏病(congenital heart disease,CHD)的诊断效能。方法回顾性分析2019-08/2023-09月作者医院收治的65例疑似CHD患儿的影像学资料,所有患儿均行心脏CTA及UCG检查。对两种检查方式的图像质量进行主观评价并比较其差异;以手术或数字减影血管造影(digital subtraction angiography,DSA)为“金标准”,对比两种检查方式在诊断CHD的灵敏度、特异度、阳性预测值、阴性预测值及准确率的差异,并应用Kappa检验比较与“金标准”结果的一致性;采用受试者工作特征(receiver operating characteristic,ROC)曲线分析两种检查方式对小儿CHD的诊断效能。结果CTA诊断小儿CHD心外畸形图像质量主观评分明显高于UCG,二者比较差异具有统计学意义(P<0.05),心内畸形图像质量主观评分二者比较差异无统计学意义(P>0.05)。两名医师对图像质量主观评分的一致性较好(κ=0.802)。CTA、UCG诊断小儿CHD心内畸形准确率比较差异无统计学意义(P>0.05);CTA诊断小儿CHD心外畸形准确率为96.43%,显著高于UCG 50.00%,组间比较差异具有统计学意义(P<0.05)。CTA诊断小儿CHD的灵敏度、特异度、阳性预测值、阴性预测值及准确率分别为90.00%、60.00%、96.43%、33.33%及87.69%,与手术或DSA结果一致性较好(κ=0.766);UCG诊断CHD的灵敏度、特异度、阳性预测值、阴性预测值及准确率分别为83.33%、20.00%、92.59%、9.09%及79.81%,与手术或DSA结果一致性一般(κ=0.522)。CTA、UCG两种检查方式诊断小儿CHD的灵敏度、特异度、阴性预测值及准确率差异比较均有统计学意义(P均<0.05)。ROC曲线分析结果显示,CTA与UCG诊断小儿CHD的曲线下面积(area under the cure,AUC)分别为0.853和0.773,二者比较差异有统计学意义(P<0.05)。结论宽体探测器CTA在小儿CHD心外畸形方面的诊断效能优于UCG,而在心内畸形方面稍差,因此建议二者联合检查,诊断价值更高。 展开更多
关键词 先天性心脏病 超声心动图 宽体探测器CT CT血管造影
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BMI指数与老年CHF患者血浆Cys-C、NT-proBNP相关性及评测预后的可行性研究
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作者 王姣 郎月 耿直 《齐齐哈尔医学院学报》 2024年第15期1423-1426,共4页
目的分析体质量指数(Body mass index,BMI)与老年慢性心力衰竭(Chronic heart failure,CHF)患者血浆胱抑素C(cystatinC,Cys-C)、N末端B型利钠肽原(N-terminal pro-B-type natriuretic peptide,NT-proBNP)水平相关性,并分析血浆Cys-C、NT... 目的分析体质量指数(Body mass index,BMI)与老年慢性心力衰竭(Chronic heart failure,CHF)患者血浆胱抑素C(cystatinC,Cys-C)、N末端B型利钠肽原(N-terminal pro-B-type natriuretic peptide,NT-proBNP)水平相关性,并分析血浆Cys-C、NT-proBNP评估老年CHF患者预后价值。方法选择2021年7月—2022年10月在本院接受治疗的192例老年慢性心力衰竭(CHF)患者作为研究对象,按照BMI指数分为肥胖组(49例)、超重组(68例)和正常组(75例)三组。对比各亚组患者血浆Cys-C、NT-proBNP水平差异,采用Pearson相关性分析的方式探究老年CHF患者BMI指数与血浆Cys-C、NT-proBNP相关性,对入组患者实施12个月随访,将患者按照预后情况区分为死亡组和存活组,对比两亚组患者血浆Cys-C、NT-proBNP水平差异并评估预后评估价值。结果肥胖组患者血浆Cys-C、NT-proBNP水平高于超重组,超重组患者血浆Cys-C、NT-proBNP水平高于正常组,差异具有统计学意义(P<0.05);入组老年CHF患者的BMI指数与其血浆Cys-C、NT-proBN水平均呈现明显的正相关性(r=0.7104,P<0.0001)(r=0.6603,P<0.0001);随访12个月显示,死亡组患者的血浆Cys-C、NT-proBNP水平显著高于存活组患者,差异具有统计学意义(P<0.05);血浆Cys-C、NT-proBNP对老年CHF预后评估曲线下面积(area under curv,AUC)为0.6930(P=0.0009)、0.7982(P<0.0001)。结论老年CHF患者随BMI指数升高,血浆Cys-C、NT-proBNP水平逐渐升高,血浆Cys-C、NT-proBNP对老年CHF临床结局具有一定的预测价值,进一步研究有推广应用于老年CHF预后评估潜力。 展开更多
关键词 体质量指数 慢性心力衰竭 胱抑素C N末端B型利钠肽原 相关性 预后评估
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冠心病患者体成分与心肺适能的相关性
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作者 李阳 马珺 +5 位作者 都屹泓 许莉 陈菡芬 邱训涵 姜萌 卜军 《上海交通大学学报(医学版)》 CAS CSCD 北大核心 2024年第1期72-78,共7页
目的·探究冠心病患者体成分与心肺适能(cardiopulmonary fitness,CRF)的相关性。方法·选取2022年10月至2023年6月于上海交通大学医学院附属仁济医院行择期经皮冠状动脉介入治疗的冠心病患者(冠心病组)以及健康体检者(健康对照... 目的·探究冠心病患者体成分与心肺适能(cardiopulmonary fitness,CRF)的相关性。方法·选取2022年10月至2023年6月于上海交通大学医学院附属仁济医院行择期经皮冠状动脉介入治疗的冠心病患者(冠心病组)以及健康体检者(健康对照组)。所有受试者均在同一日接受心肺运动试验(cardiopulmonary exercise testing,CPET)测定CRF,以及生物电阻抗分析(bioelectrical impedance analysis,BIA)测定身体成分。结果·共纳入冠心病患者191例、健康体检者188例。2组基线特征差异均无统计学意义。与健康对照组相比,冠心病患者CRF指标均显著降低(均P<0.05);在体成分指标中,冠心病组躯干肌肉质量(trunk muscle mass,TMM)显著低于健康对照组(P<0.01),躯干脂肪质量(trunk fat mass,TFM)显著高于健康对照组(P<0.01)。相关性分析显示,冠心病组TMM(R=0.538)、下肢肌肉质量(lower limbs muscle mass,LMM)(R=0.754)、下肢脂肪质量(lower limbs fat mass,LFM)(R=0.593)与每千克体质量峰值摄氧量(VO_(2peak)/kg)呈正相关(均P<0.01),TFM(R=−0.563)与VO_(2peak)/kg呈负相关(P<0.01)。其余体成分指标与VO_(2peak)/kg之间相关性均无统计学意义。依据VO_(2peak)/kg将冠心病患者分为低CRF组、中CRF组和高CRF组,结果发现3组患者LMM、TMM、LFM、TFM之间差异均存在统计学意义(均P<0.05)。多元线性回归分析提示年龄、性别、TMM、TFM、LMM、LFM均是冠心病患者VO_(2peak)/kg的相关因素。冠心病患者的VO_(2peak)/kg随着TMM、LMM、LFM的升高而升高,随着年龄和TFM的升高而下降,女性相比于男性患者VO_(2peak)/kg更低。结论·冠心病患者的CRF显著低于健康人群,TFM更高,TMM更低;在冠心病患者中,CRF与TFM呈负相关,与TMM、LMM以及LFM呈正相关。 展开更多
关键词 冠心病 心肺适能 体成分
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基于可穿戴系统的体位/体动信息量化及其与心力衰竭患者NYHA分级关联分析
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作者 寇宇晴 王文青 +8 位作者 李梦伟 亢玉 张秀 喻鹏铭 颜伟 曹德森 晏沐阳 张庆 张政波 《解放军医学院学报》 CAS 2024年第1期59-66,共8页
背景日常活动量减少和运动功能受限是心力衰竭患者的特征性表现之一,体位/体动信息与心衰患者疾病严重程度和预后密切相关。通过可穿戴生理监测系统量化体位/体动信息或可作为一种潜在的心衰病情严重程度定量评价手段,其与纽约心脏病协... 背景日常活动量减少和运动功能受限是心力衰竭患者的特征性表现之一,体位/体动信息与心衰患者疾病严重程度和预后密切相关。通过可穿戴生理监测系统量化体位/体动信息或可作为一种潜在的心衰病情严重程度定量评价手段,其与纽约心脏病协会(New York Heart Association,NYHA)心功能分级的关系需进一步研究。目的探讨心衰患者体位/体动信息定量分析结果与NYHA分级的相关性。方法纳入2021年5月—2022年11月在四川大学华西医院心内科住院的心衰患者,通过可穿戴生理监测系统采集患者入院当天和出院前1 d各24 h的连续生理监测数据,同步收集临床数据。通过对可穿戴生理监测系统内的三轴加速传感器信息进行处理分析,计算卧床时间、活动时间、步数、睡眠翻身次数4个体位/体动指标。基于患者入院时NYHA分级、入院和出院情况、出院时NYHA分级改善与否进行分组,分析体位/体动指标与NYHA分级的关联性。结果纳入心衰患者69例,平均年龄(60.90±14.24)岁,其中男性40例,NYHAⅡ、Ⅲ、Ⅳ级的患者分别有9例、24例、36例。随着NYHA分级的升高,心衰患者全天的卧床时间占比逐渐增多,而全天的活动时间占比、平均每小时步数逐渐降低,以上3个指标在NYHAⅡ、Ⅲ、Ⅳ级间均有统计学差异(P均<0.05);其中卧床时间占比(r_(s)=0.319,P=0.008)与NYHA分级呈正相关,活动时间占比(r_(s)=-0.312,P=0.009)、平均每小时步数(r_(s)=-0.309,P=0.010)与NYHA分级存在负相关。出院时的卧床时间占比显著低于入院时(96.25%vs 97.63%,P=0.026);出院时的活动时间占比显著高于入院时(3.32%vs 1.78%,P<0.001);出院时的平均每小时步数显著高于入院时(97.17步/h vs 35.58步/h,P<0.001);其中出院时NYHA改善组患者的体位/体动指标变化趋势同上,未改善组仅出院时的平均每小时步数显著高于入院时,NYHA改善组的出入院平均每小时步数变化值显著高于未改善组(71.21步/h vs 21.31步/h,P=0.003)。结论可穿戴生理监测系统能够对心衰患者的体位/体动信息进行客观长程的监测,心衰患者的卧床时间与NYHA分级呈正相关关系;活动时间、步数与NYHA分级呈负相关关系,这些体位/体动指标或可作为心衰患者疾病严重程度分级和状态监测评估的有用指标,未来可进一步延伸到对患者的居家和长程监测。 展开更多
关键词 心力衰竭 体位/体动 NYHA分级 可穿戴系统 生理监测系统
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徐凤芹从“心主神明”辨治失眠经验
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作者 翁家俊 环璐瑶 +3 位作者 李的徽 张诗雨 张艳虹 徐凤芹(指导) 《山东中医杂志》 2024年第7期739-744,共6页
失眠病位主要在心,涉及肝、脾、肾。心神失养或实邪内扰、心神不宁皆可导致失眠。临证宜分清脏腑病位、标本虚实。肝郁血虚、心神失养者,常以柴胡加龙骨牡蛎汤或解郁合欢汤加减;痰热内盛,扰动心神者,常以半夏秫米汤或十味温胆汤加减;心... 失眠病位主要在心,涉及肝、脾、肾。心神失养或实邪内扰、心神不宁皆可导致失眠。临证宜分清脏腑病位、标本虚实。肝郁血虚、心神失养者,常以柴胡加龙骨牡蛎汤或解郁合欢汤加减;痰热内盛,扰动心神者,常以半夏秫米汤或十味温胆汤加减;心脉瘀阻、心神不宁者,常以血府逐瘀汤加减。老年人作为特殊的群体,失眠病位多在心肾,常合并脾胃虚弱,可选用交泰丸或合用归脾汤加减,并强调对于原发病的治疗和药物因素。失眠患者也需适当使用安神药物。在安神药物配伍上,多基于辨证论治角度,结合现代药理研究精妙施用安神药物。 展开更多
关键词 徐凤芹 失眠 心主神明 心神失养 实邪内扰 安神
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基于形气神一体观构建冠心病的病机理论体系
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作者 潘婷婷 张泽 《山东中医杂志》 2024年第7期675-679,共5页
形气神一体观是中医理论体系的重要组成部分。形、气、神三者对人体生命活动具有重要作用,与冠心病的发生、发展关系密切。分析形、气、神三者之间的密切联系,从形气神一体观的角度探讨形、气、神与冠心病的关系,阐述冠心病病机。冠心... 形气神一体观是中医理论体系的重要组成部分。形、气、神三者对人体生命活动具有重要作用,与冠心病的发生、发展关系密切。分析形、气、神三者之间的密切联系,从形气神一体观的角度探讨形、气、神与冠心病的关系,阐述冠心病病机。冠心病形的改变以心血不足为主,而痰浊、瘀血为主要致病因素;气的变化包括气虚、阳虚和气滞等方面;神的异常以由于心神失养造成的狭义之神调控情志、认知、思维等精神活动功能失常为主。 展开更多
关键词 冠心病 胸痹心痛 病机
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尿酸介导体重指数与慢性心力衰竭关系的孟德尔随机化分析
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作者 葛腾 房瑛 +3 位作者 齐鸿飞 宁博 吴永青 赵明君 《中国循环杂志》 CSCD 北大核心 2024年第5期495-502,共8页
目的:采用两样本孟德尔随机化分析探讨体重指数、尿酸与慢性心力衰竭(CHF)之间的因果关系。方法:使用公开的东亚人群全基因组关联研究汇总数据集,以逆方差加权(IVW)法为主要分析方法,同时采用MR-Egger回归法、加权中位数模型、简单模型... 目的:采用两样本孟德尔随机化分析探讨体重指数、尿酸与慢性心力衰竭(CHF)之间的因果关系。方法:使用公开的东亚人群全基因组关联研究汇总数据集,以逆方差加权(IVW)法为主要分析方法,同时采用MR-Egger回归法、加权中位数模型、简单模型、加权模型,分析体重指数、尿酸与CHF两两之间的关系。使用MR-Egger回归法检测多效性,使用Cochran Q检验检测异质性,使用留一法进行敏感性分析,绘制漏斗图检测偏倚性,使用MR-PRESSO包剔除离群单核苷酸多态性(SNP)。孟德尔分析后计算中介效应值及中介效应比例,最后分析体重指数、尿酸与CHF两两之间的反向孟德尔随机化研究。结果:两样本孟德尔分析中IVW法显示体重指数(OR=1.685,95%CI:1.417~2.003,P<0.001)、尿酸(OR=1.225,95%CI:1.087~1.380,P<0.001)均与CHF存在因果关系;体重指数(OR=1.204,95%CI:1.139~1.273,P<0.001)与尿酸存在因果关系。尿酸在体重指数与CHF的因果关系中的中介效应比例为7.23%。MR-Egger回归截距的P均>0.05,即筛选出的SNP不存在水平多效性,因果推断方法有效,体重指数-尿酸、体重指数-CHF的孟德尔随机化分析存在异质性(Cochran Q检验P<0.01)。反向孟德尔随机化分析中IVW法显示,CHF与体重指数(OR=0.977,95%CI:0.947~1.008,P>0.05)、CHF与尿酸(OR=1.000,95%CI:0.963~1.038,P>0.05)之间均不存在因果关系,尿酸与体重指数的分析存在基因多效性,故因果推断方法无效。结论:体重指数、尿酸均与CHF存在因果关系且呈正相关,且尿酸在体重指数与CHF的因果关系中为不完全中介因素。 展开更多
关键词 体重指数 尿酸 慢性心力衰竭 孟德尔随机化分析 因果关系 中介效应
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共享决策护理在冠心病PCI术后患者中的应用效果及对机体状态的影响
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作者 高琳英 郭瑜 +1 位作者 王红 高鑫 《临床医学研究与实践》 2024年第23期163-166,共4页
目的探讨共享决策护理在冠心病经皮冠状动脉介入治疗(PCI)术后患者中的应用效果及对机体状态的影响。方法选取2021年7月至2022年7月接受PCI治疗的80例冠心病患者为研究对象,运用随机数字表法将其分为对照组、观察组,各40例。对照组接受... 目的探讨共享决策护理在冠心病经皮冠状动脉介入治疗(PCI)术后患者中的应用效果及对机体状态的影响。方法选取2021年7月至2022年7月接受PCI治疗的80例冠心病患者为研究对象,运用随机数字表法将其分为对照组、观察组,各40例。对照组接受常规护理,观察组接受共享决策护理。比较两组的健康行为、依从性及机体状态。结果护理后,观察组的健康行为量表(HPL)各维度评分均高于对照组,差异具有统计学意义(P<0.05)。护理后,观察组的通用依从性量表(GAS)各维度评分均高于对照组,差异具有统计学意义(P<0.05)。护理后,观察组的西雅图心绞痛量表(SAQ)各维度评分均高于对照组,差异具有统计学意义(P<0.05)。结论共享决策护理可提升冠心病PCI术后患者的依从性,提升健康行为改善效果,进而改善机体状态。 展开更多
关键词 冠心病 经皮冠状动脉介入治疗 共享决策 健康行为 机体状态
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浮针调颈联合调神调衡针治疗心脾两虚型失眠38例
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作者 王彦璎 张振营 +3 位作者 马良志 张蕊 徐慧颖 高楠(指导) 《光明中医》 2024年第4期736-739,共4页
目的观察浮针调颈联合调神调衡针治疗心脾两虚型失眠的临床疗效。方法选取日照市中医院2021年11月—2022年6月收治的心脾两虚型失眠患者38例。治疗3周,以匹兹堡睡眠质量指数(PSQI)量表进行评估,进行自身对照研究。结果治疗后,总有效率为... 目的观察浮针调颈联合调神调衡针治疗心脾两虚型失眠的临床疗效。方法选取日照市中医院2021年11月—2022年6月收治的心脾两虚型失眠患者38例。治疗3周,以匹兹堡睡眠质量指数(PSQI)量表进行评估,进行自身对照研究。结果治疗后,总有效率为97.37%(37/38),愈显率89.47%(34/38);随访时,总有效率为97.37%(37/38),愈显率73.68%(28/38)。结论浮针调颈联合调神调衡针可明显改善心脾两虚型失眠患者的睡眠状况,具有良好的临床疗效。 展开更多
关键词 失眠 心脾两虚证 浮针 调神调衡针
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