1-取代苯氧乙酰基-4-芳酰基氨基硫脲的合成及生物活性

A series of 1 substituted phenoxyacetyl 4 aroyl thiosemicarbazides were synthe sized by reaction of aroylisothiocyanate with (substituted)phenoxyacetic acid hydrazides under solid liquid phase transfer catalysis condition. The preliminary bioassay results showed that some of the compounds have good antibiotic activity and plant growth regulation activity. The compounds were characterized by elemental analysis, IR and 1H NMR.

取代苯氧乙酸的合成及生物活性研究

以碱性水溶液为溶剂,以聚乙二醇-800为催化剂,一氯乙酸与5种取代苯酚合成了5种取代苯氧乙酸。各化合物结构经IR、1H NMR、元素分析进行表征,并对5种化合物进行了初步的室内生物活性测定,结果表明所合成的大部分化合物对所测菌种都有抑制作用。