Impact of the Rapid Recovery Concept on Complications and Patient Quality of Life in the Perioperative Nursing of Robot-Assisted Radical Oesophageal Cancer

Aim: This study evaluates the impact of Enhanced Recovery After Surgery (ERAS) nursing on postoperative complications and quality of life in patients undergoing robot-assisted minimally invasive esophagectomy (RAMIE). Methods: A total of 150 patients who underwent RAMIE from January 2020 to January 2022 at our hospital were randomly assigned to either the observation group or the control group, with 75 patients in each. The control group received standard perioperative management and nursing care, while the observation group was treated with ERAS nursing strategies. Interventions continued until discharge, and outcomes such as postoperative complications, quality of life, and nutritional status were compared between the groups. Results: The observation group exhibited a significantly lower incidence of postoperative adverse reactions compared to the control group (P ionally, all dimension scores of the Short-Form 36 Health Survey (SF-36), including the total score, were higher in the observation group (P < 0.05). Furthermore, the Nutritional Risk Screening (NRS) scores for impaired nutritional status and disease severity, along with the total NRS score, were significantly lower in the observation group compared to the control group (P Conclusion: Implementing ERAS nursing in the perioperative care of patients undergoing RAMIE is associated with reduced postoperative complications and enhanced postoperative quality of life and nutritional status. .

Application of neoadjuvant chemoradiotherapy and neoadjuvant chemotherapy in curative surgery for esophageal cancer:A metaanalysis

BACKGROUND The effectiveness of neoadjuvant therapy in esophageal cancer(EC)treatment is still a subject of debate.AIM To compare the clinical efficacy and toxic side effects between neoadjuvant chemoradiotherapy(nCRT)and neoadjuvant chemotherapy(nCT)for locally advanced EC(LAEC).METHODS A comprehensive search was conducted using multiple databases,including PubMed,EMBASE,MEDLINE,Science Direct,The Cochrane Library,China National Knowledge Infrastructure,Wanfang Database,Chinese Science and Technology Journal Database,and Chinese Biomedical Literature Database Article.Studies up to December 2022 comparing nCRT and nCT in patients with EC were selected.RESULTS The analysis revealed significant differences between nCRT and nCT in terms of disease-free survival.The results indicated that nCRT provided better outcomes in terms of the 3-year overall survival rate(OSR)[odds ratio(OR)=0.95],complete response rate(OR=3.15),and R0 clearance rate(CR)(OR=2.25).However,nCT demonstrated a better 5-year OSR(OR=1.02)than nCRT.Moreover,when compared to nCRT,nCT showed reduced risks of cardiac complications(OR=1.15)and pulmonary complications(OR=1.30).CONCLUSION Overall,both nCRT and nCT were effective in terms of survival outcomes for LAEC.However,nCT exhibited better performance in terms of postoperative complications.

Impact of thoracic paravertebral block and sufentanil on outcomes and postoperative cognitive dysfunction in thoracoscopic lung cancer surgery

BACKGROUND Postoperative pain management and cognitive function preservation are crucial for patients undergoing thoracoscopic surgery for lung cancer(LC).This is achieved using either a thoracic paravertebral block(TPVB)or sufentanil(SUF)-based multimodal analgesia.However,the efficacy and impact of their combined use on postoperative pain and postoperative cognitive dysfunction(POCD)remain unclear.AIM To explore the analgesic effect and the influence on POCD of TPVB combined with SUF-based multimodal analgesia in patients undergoing thoracoscopic radical resection for LC to help optimize postoperative pain management and improve patient outcomes.METHODS This retrospective analysis included 107 patients undergoing thoracoscopic radical resection for LC at The Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital between May 2021 and January 2023.Patients receiving SUF-based multimodal analgesia(n=50)and patients receiving TPVB+SUF-based multimodal analgesia(n=57)were assigned to the control group and TPVB group,respectively.We compared the Ramsay Sedation Scale and visual analog scale(VAS)scores at rest and with cough between the two groups at 2,12,and 24 h after surgery.Serum levels of epinephrine(E),angio-tensin Ⅱ(Ang Ⅱ),norepinephrine(NE),superoxide dismutase(SOD),vascular endothelial growth factor(VEGF),transforming growth factor-β1(TGF-β1),tumor necrosis factor-α(TNF-α),and S-100 calcium-binding proteinβ(S-100β)were measured before and 24 h after surgery.The Mini-Mental State Examination(MMSE)was administered 1 day before surgery and at 3 and 5 days after surgery,and the occurrence of POCD was monitored for 5 days after surgery.Adverse reactions were also recorded.RESULTS There were no significant time point,between-group,and interaction effects in Ramsay sedation scores between the two groups(P>0.05).Significantly,there were notable time point effects,between-group differences,and interaction effects observed in VAS scores both at rest and with cough(P<0.05).The VAS scores at rest and with cough at 12 and 24 h after surgery were lower than those at 2 h after surgery and gradually decreased as postoperative time increased(P<0.05).The TPVB group had lower VAS scores than the control group at 2,12,and 24 h after surgery(P<0.05).The MMSE scores at postoperative days 1 and 3 were markedly higher in the TPVB group than in the control group(P<0.05).The incidence of POCD was significantly lower in the TPVB group than in the control group within 5 days after surgery(P<0.05).Both groups had elevated serum E,Ang Ⅱ,and NE and decreased serum SOD levels at 24 h after surgery compared with the preoperative levels,with better indices in the TPVB group(P<0.05).Marked elevations in serum levels of VEGF,TGF-β1,TNF-α,and S-100β were observed in both groups at 24 h after surgery,with lower levels in the TPVB group than in the control group(P<0.05).CONCLUSION TPVB combined with SUF-based multimodal analgesia further relieves pain in patients undergoing thoracoscopic radical surgery for LC,enhances analgesic effects,reduces postoperative stress response,and inhibits postoperative increases in serum VEGF,TGF-β1,TNF-α,and S-100β levels.This scheme also reduced POCD and had a high safety profile.

Influence of the dexmedetomidine combined with parecoxib sodium on inflammatory factor, blood gas analysis and stress hormone levels in patients undergoing radical resection of esophageal carcinoma during one lung ventilation

Objective: To investigate the effect of dexmedetomidine combined with parecoxib sodium on the levels of inflammatory factors, blood gas analysis and stress hormone in patients undergoing radical resection of esophageal carcinoma during one lung ventilation. Methods:According to the random data table, 81 cases of esophageal cancer patients were divided into the control group (n=41) and observation group (n=40), the patients in the two groups underwent left thoracotomy esophageal cancer radical resection, the control group patients were treated with parecoxib sodium, and patients in the observation group were treated with parecoxib sodium combined with dexmedetomidine medetomidine treatment, before induction of anesthesia (T0), 30 min of one lung ventilation (T1) and 120 min after operation (T2) at three time points, the levels of inflammatory factors [tumor necrosis factor-α (TNF-α), C reactive protein (CRP)], blood gas analysis[oxygen partial pressure (PaO2), carbon dioxide partial pressure (PaCO2)] and stress hormone[epinephrine (E), norepinephrine (NE)] of the two groups were compared. Results: Intra group level comparison, compared with the levels of two groups at the T0 moment, the levels of TNF-α, CRPand NE of theT1 and T2 moment were significantly increased, the level of PaO2 were significantly decreased, and T2 moment levels were significantly higher than that of T1 moment, the difference was statistical significance;There were no significant differences between the two groups of the levels of TNF-α, CRP, PaO2, E and NE of the T0 moment, the levels of TNF-α, CRP, E and NE of the observation group at the T1 and T2 moment were significantly lower than the control group, at the same time the PaO2 level was significantly higher than the control group, the difference was statistically significant;There were no statistically significant differences in PaCO2 levels between groups and at any time. Conclusion: Dexmedetomidine combined with parecoxib sodium can effectively relieve the inflammatory stress, improve the levels of the blood gas analysis index and stress hormone during one lung ventilation, has an important clinical value.

Effect of Goal-Directed Fluid Therapy on Lung Function, Cognitive Function and Inflammatory Response in Patients Undergoing Radical Esophageal Cancer Surgery under One-Lung Ventilation

Objective: To explore the effects of goal-directed fluid therapy (GDFT) on lung function, cognitive function and inflammatory response in patients undergoing radical esophageal cancer surgery under one-lung ventilation. Methods: Sixty-seven patients undergoing radical esophageal cancer surgery were divided into GDFT group (GDFT therapy) and control group (conventional liquid therapy). The changes in patients’ pulmonary function, cognitive function and inflammatory response were evaluated. Results: Both alveolar-arterial oxygen partial pressure difference [P(A-a)O2] and respiratory index (RI) increased at one-lung ventilation for 30 minutes (T2) and decreased at one-lung ventilation for 60 minutes (T3), and after surgery (T4) in the two groups, and the GDFT group was lower than the control group (P < 0.05);theoxygenation index (OI) of the two groups decreased at T2, T3, and T4 compared with that at T1 (before one-lung ventilation), and the GDFT group was higher than the control group (P < 0.05). At T4 and T5, the tumor necrosis factor α (TNF-α), interleukin 6 (IL-6), central nervous system specific protein (S100β), and neuron specific enolase (NSE) in the GDFT group were lower compared to the control group (P < 0.05), while interleukin-10 (IL-10) was higher compared to the control group (P < 0.05);the incidence of perioperative neurocognitive disorder (PND) in the GDFT group was lower than that in the control group (P < 0.05). Conclusion: GDFT can help prevent lung injury during radical esophageal cancer surgery under one-lung ventilation, reduce the body’s inflammatory response, and reduce the incidence of perioperative cognitive disorder to a certain extent.

胸椎旁神经阻滞联合全身麻醉在胸腔镜肺癌根治术患者中的应用效果

目的探讨胸椎旁神经阻滞联合全身麻醉在胸腔镜肺癌根治术患者中的应用效果。方法根据麻醉方法的不同将65例胸腔镜肺癌根治术患者分为全麻组(n=31,单纯全身麻醉)和联合组(n=34,胸椎旁神经阻滞联合全身麻醉)。比较两组患者的疼痛情况[视觉模拟评分法(VAS)评分、术后24 h镇痛泵按压次数]、瑞芬太尼用量、苏醒进程指标、应激反应指标[去甲肾上腺素(NE)、超氧化物歧化酶(SOD)、丙二醛(MDA)]及术后并发症发生情况。结果术后2、6、12、24 h,联合组患者VAS评分均明显低于全麻组(P﹤0.01);联合组患者术后24 h镇痛泵按压次数明显少于全麻组(P﹤0.01)。联合组患者瑞芬太尼用量明显少于全麻组,苏醒时间和自主呼吸恢复时间均明显短于全麻组,差异均有统计学意义(P﹤0.01)。术后,两组患者NE、MDA水平均高于本组术前,SOD水平均低于本组术前,联合组患者NE、MDA水平均低于全麻组,SOD水平高于全麻组,差异均有统计学意义(P﹤0.05)。联合组患者术后并发症总发生率低于全麻组(P﹤0.05)。结论胸椎旁神经阻滞联合全身麻醉应用于胸腔镜肺癌根治术患者,不仅能够减轻疼痛程度和应激反应程度,还能够减少阿片类药物用量,降低并发症发生率。

达芬奇机器人辅助下肝癌根治术的临床疗效及围手术期护理路径的构建

目的:探究达芬奇机器人辅助下肝癌根治术的临床疗效以及护理路径在患者围手术期的应用效果。方法:选取2020年1月—2022年12月在四川省人民医院和成都市第三人民医院接受达芬奇机器人辅助下肝癌根治术的80例患者,采用随机数字表法将其分为研究组和对照组,各40例。对照组给予常规护理干预,研究组给予临床护理路径(CNP)。对比两组临床疗效、肝功能指标、生活质量评分、心理状态评分及住院指标。结果:所有手术均顺利完成,仅有1例胆漏,3例肝断面积液,经保守治疗后相关患者症状均消失;随访6~36个月所有患者均无复发或死亡;比较两组术后肝功能指标、各项生活质量评分、心理状态评分,差异具有统计学意义(P>0.05);出院前,两组肝功能指标和心理状态评分均明显降低,两组各项生活质量评分均明显升高,且研究组明显优于对照组,差异具有统计学意义(P<0.05);研究组卧床时间、住院时间、住院费用明显低于对照组,差异具有统计学意义(P<0.05)。结论:达芬奇机器人辅助下肝癌根治术能够取得良好的手术效果。同时与传统护理干预措施相比,临床护理路径构建的标准化护理流程能够改善患者肝功能、提高生活质量、调节不良情绪,具有较高的临床应用和推广价值。

术中改良体位联合风险管理对机器人辅助下直肠癌根治术患者术后疼痛及并发症发生风险的影响

目的:探讨术中改良体位联合风险管理对机器人辅助下直肠癌根治术患者术后疼痛及并发症发生风险的影响。方法:选取2021年6月—2022年6月浙江大学医学院附属第一医院行常规护理的38例机器人辅助下直肠癌根治术患者作为研究对象,将其纳入对照组;另选取2022年7月—2023年7月于本院行术中改良体位联合风险管理的38例患者作为研究对象,将其纳入观察组。所有患者均护理14 d,比较两组手术相关指标、术后恢复指标、并发症发生率、不同时点疼痛水平。结果:观察组手术时间短于对照组,术中失血量少于对照组(P<0.05);观察组术后首次排气、排便、下床活动及住院时间短于对照组(P<0.05);观察组术后VAS评分低于对照组(P<0.05);观察组并发症发生率低于对照组(P<0.05)。结论:术中改良体位联合风险管理能够有效缓解机器人辅助下直肠癌根治术患者的应激反应,减轻术后疼痛,降低术后并发症发生风险,促进术后康复。

目标导向液体治疗在胸腔镜肺癌根治术中的应用

目的探讨目标导向液体治疗(GDFT)在胸腔镜肺癌根治术中的应用价值。方法94例行胸腔镜肺癌根治术患者随机分为观察组和对照组。观察组采用GDFT,对照组采用常规液体治疗。比较两组患者围术期的血流动力学指标、术中肺通气功能指标、手术观察指标和认知功能。结果在单肺通气1 h和术毕即刻,观察组的平均动脉压(MAP)、中心静脉压(CVP)、呼吸指数(RI)均明显低于对照组,而脑氧饱和度(rSO_(2))和氧合指数(OI)均明显高于对照组(P<0.05或0.01)。观察组胶体补液量、晶体补液量、尿量、补液总量均明显少于对照组,使用血管活性药物构成比低于对照组(P<0.05或0.01)。术后1 d时,观察组的智力状态检查量表(MMSE)评分明显高于对照组,认知功能障碍发生率低于对照组(P<0.05)。结论在胸腔镜肺癌根治术中采用GDFT能够稳定血流动力学,控制容量负荷,减少血管活性药物的使用率,减轻肺通气功能损伤和降低认知功能障碍发生率。

基于膜解剖理论的胸、腹腔镜联合食管癌根治术

目的探讨膜解剖理论应用于胸、腹腔镜联合食管癌根治术的可行性及临床意义。方法回顾性分析2018年12月~2021年10月行基于膜解剖理论的胸、腹腔镜联合食管癌根治术142例资料。将食管系膜、食管癌以及食管系膜内的神经、血管、淋巴系统、脂肪组织、胃上部、胃左系膜、胃左淋巴结作为一个整体切除。术中可见食管周围含疏松结缔组织的间隙为食管筋膜融合间隙。前10例使用纳米炭示踪标记,显示食管淋巴液引流至胃左淋巴结。结果142例手术顺利,手术时间150~230(184.6±21.3)min,术中出血量20~100(46.7±16.8)ml,清扫淋巴结12~41(23.5±7.3)枚,97例淋巴结阳性;术后胸腔引流时间3~10(7.1±2.5)d,经口进流食时间5~10(7.6±1.7)d,总住院时间9~20(14.0±4.6)d。术后并发症发生率21.8%(31/142),包括吻合口漏7例(4.9%),吻合口狭窄9例(6.3%),声音嘶哑9例(6.3%),残胃炎6例(4.2%)。无术后出血、乳糜漏、感染或术后30 d内死亡。142例随访11~35个月,中位数26个月,无复发和死亡。结论食管周围存在构成“信封”的系膜结构,膜解剖理论适用于食管癌的治疗,基于膜解剖理论的食管癌根治术安全、有效、可行。

ERAS护理模式联合病友互助模式在肺癌根治术后老年患者康复中的应用效果

目的探讨ERAS护理模式联合病友互助模式在肺癌根治术老年患者中的康复效果。方法选取河南省胸科医院,郑州大学附属胸科医院2021年10月至2022年10月收治的78例肺癌根治术患者,按随机数字表法分为对照组和观察组,各39例。对照组采用常规护理,观察组采用ERAS护理联合病友互助模式。比较两组干预后的围手术期指标、疼痛评分、肺功能指标、希望水平及病耻感评分。结果观察组围手术期指标改善优于对照组;观察组术后12 h、后24 h、后72 h疼痛评分低于对照组;观察组二氧化碳分压(PaCO_(2))、血氧分压(PaO_(2))、血氧饱和度(SpO_(2))水平高于对照组;观察组希望水平评分高于对照组,病耻感评分低于对照组,差异有统计学意义(P<0.05)。结论ERAS护理模式联合病友互助模式有效改善老年肺癌根治术患者围手术期指标和肺功能,降低疼痛程度,提高希望水平,降低病耻感。

竖脊肌平面阻滞对胸腔镜下老年肺癌根治术后谵妄及认知功能的影响

目的明确竖脊肌平面阻滞对胸腔镜下肺癌根治术老年患者术后谵妄和认知功能的影响。方法选取行胸腔镜下肺癌根治术的90例老年患者作为研究对象,随机分为对照组、观察组,每组45例。对照组患者实施常规全身麻醉,观察组患者在全身麻醉前行竖脊肌平面阻滞。对2组患者不同时点的生命体征、阿片类药物用量、镇痛泵按压次数、切口疼痛视觉模拟量表(VAS)评分、认知功能和术后谵妄情况进行比较。结果在麻醉结束时,观察组患者的平均动脉压(MAP)及心率明显低于对照组(P<0.05)。观察组患者手术过程中瑞芬太尼用量、围术期舒芬太尼用量和镇痛泵按压次数均显著少于对照组(P<0.05)。在术后6 h、12 h、24 h及48 h,观察组患者的切口疼痛VAS评分显著低于对照组(P<0.05)。观察组患者术后6 h及24 h的认知功能评分均显著高于对照组(P<0.05);对照组术后6 h及24 h的谵妄发生率显著高于观察组(P<0.05)。结论竖脊肌平面阻滞可以显著缓解胸腔镜下肺癌根治术老年患者的围术期疼痛状况,减少阿片类药物用量,降低术后谵妄发生率,还可以改善患者术后认知功能,为降低术后精神类疾病发生率提供了一种新思路。

舒更葡糖钠对胸腔镜肺癌根治术后患者肌松恢复及凝血功能的影响

目的探讨舒更葡糖钠注射液对胸腔镜肺癌根治术后患者肌松恢复及凝血功能的影响。方法选取2020年2月至2022年1月在江苏大学附属镇江三院、常州市第七人民医院于全麻下行胸腔镜肺癌根治术的86例患者为研究对象。应用随机数字表法将患者分成A、B两组,每组各43例。两组麻醉诱导和术中全麻维持方案相同,使用肌松监测仪(TOF)监测肌松。手术结束后,TOF计数≥2时,A组静脉推注新斯的明(2 mg/kg)、阿托品(0.5 mg/kg)逆转肌松药,B组静脉推注舒更葡糖钠(2 mg/kg)。记录推注肌松拮抗药后5、15、30 min时肌松残余率。观察注射罗库溴铵后5 min(T0)、推注肌松拮抗药后5 min(T1)、15 min(T2)、30 min(T3)时血浆凝血酶时间(TT)、活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、纤维蛋白原(FIB)水平。同时记录气管导管拔除时间及患者发生恶心、呕吐等情况。结果A组给予肌松拮抗药5、15 min后肌松残余率明显高于B组(100.00%vs 13.95%,65.12%vs 0.00%)(χ^(2)=64.939、41.517,P<0.01)。两组患者在相同时间点TT、APTT、PT、FIB指标差异均无统计学意义(P均>0.05)。B组气管导管拔管时间[(3.8±1.1)min]短于A组[(13.9±4.3)min],差异有统计学意义(t=14.922,P<0.001);B组呼吸抑制发生率低于A组(0.00%vs 11.63%)(χ^(2)=5.309,P=0.021)。结论舒更葡糖钠注射液用于胸腔镜肺癌根治术患者,可快速拮抗罗库溴铵的肌松作用,降低肌松残余发生率,缩短气管导管拔管时间,利于患者术后康复。

单操作孔电视胸腔镜肺癌根治术治疗非小细胞肺癌患者的疗效观察

目的观察单操作孔电视胸腔镜(VATS)肺癌根治术对非小细胞肺癌(NSCLC)血管内皮生长因子受体2(VEGFR2)、胸苷激酶1(TK1)水平的影响。方法我院收治的245例NSCLC患者,按手术方式分为对照组(三孔胸腔镜肺癌根治术,n=115)和观察组(单操作孔VATS肺癌根治术,n=130),比较两组围术期指标、视觉模拟(VAS)评分、肺功能、炎性因子、肿瘤标志物、VEGFR2、TK1水平及并发症。结果观察组术中出血量较对照组少(P<0.05);术后,观察组VAS评分、炎性因子、肿瘤标志物和VEGFR2、TK1水平低于对照组,肺功能高于对照组(P<0.05)。结论单操作孔VATS肺癌根治术治疗NSCLC出血量少、疼痛轻,可改善肺功能,降低炎性因子、肿瘤标志物和VEGFR2、TK1水平,且不增加术后并发症,值得临床推广。

前馈控制护理干预在机器人辅助胸腔镜肺癌根治术患者麻醉恢复管理中的应用

目的探讨前馈控制护理干预在机器人辅助胸腔镜肺癌根治术患者麻醉恢复管理中的应用。方法选取2021年12月至2022年5月山东省聊城市人民医院实施机器人辅助胸腔镜肺癌根治术的64例患者为研究对象,随机将其分为对照组和试验组,每组各32例。对照组患者给予常规护理措施,试验组患者在对照组的基础上采用前馈控制下的护理干预。比较两组患者的护士相关理论知识合格率、围手术期并发症发生情况、护理满意度、护理质量评分、恢复室停留时间、术前及出恢复室时的焦虑自评量表(self-rating anxiety scale,SAS)及抑郁自评量表(self-rating depression scale,SDS)评分。结果试验组患者的护士相关理论知识合格率显著高于对照组(P<0.05);试验组患者的压力性损伤总发生率及液路问题、躁动、低体温发生率均显著低于对照组(P<0.05);试验组患者的护理效果、护理专业性、护理操作、护理态度评分均显著高于对照组,恢复室停留时间显著短于对照组(P<0.05)。出恢复室时,试验组患者的SAS、SDS评分均显著低于本组术前及对照组(P<0.05)。结论前馈控制护理干预应用于机器人辅助胸腔镜肺癌患者麻醉恢复期管理,可有效降低围手术期并发症发生率,缩短麻醉恢复时间,提高护理满意度和护理质量评分,改善患者的术后早期焦虑和抑郁状况,值得临床应用推广。

单孔胸腔镜肺癌根治术联合阶梯性镇痛干预在肺癌患者中的应用效果

目的探讨单孔胸腔镜肺癌根治术联合阶梯性镇痛干预在肺癌患者中的应用效果。方法将210例肺癌患者根据干预方式的不同分为常规组(n=100)和镇痛组(n=110),两组患者均行单孔胸腔镜肺癌根治术,常规组患者围手术期接受常规干预,镇痛组患者围手术期接受阶梯性镇痛干预。比较两组患者的术后指标、镇痛情况、肺功能指标[最大自主通气量(MVV)、用力肺活量(FVC)、第1秒用力呼气容积(FEV_(1))]、疼痛程度[视觉模拟评分法(VAS)]、认知功能[简易智力状态检查量表(MMSE)]及满意情况。结果镇痛组患者首次下床时间、引流管留置时间均明显短于常规组,镇痛药物使用率明显低于常规组,总满意率明显高于常规组,差异均有统计学意义(P﹤0.01)。干预后2天,两组患者FVC、MVV、FEV_(1)及VAS评分均低于本组干预前1天,MMSE评分高于本组干预前1天,镇痛组患者FVC、MVV、FEV_(1)及MMSE评分均高于常规组,VAS评分低于常规组,差异均有统计学意义(P﹤0.05)。结论单孔胸腔镜肺癌根治术联合阶梯性镇痛干预可以促进肺癌患者术后恢复,有效减轻患者疼痛,改善患者认知状态及肺功能,提高患者的满意度。

老年食管癌根治术患者出院准备度现状及其影响因素

目的调查了解老年食管癌根治术患者出院准备度现状,并分析其影响因素。方法选取2021年11月—2022年4月江苏省盐城市某三级甲等医院胸外科住院治疗的老年食管癌根治术患者,采用一般资料调查表、出院准备度量表、出院指导质量量表、疾病不确定感量表、社会支持评定量表进行调查。采用多元线性回归分析老年食管癌根治术患者的出院准备度的影响因素。结果老年食管癌根治术患者出院准备度总分为108.23±12.79分,出院指导质量总分为96.50±11.76分,疾病不确定感总分为117.05±13.17分,社会支持总分为28.08±5.21分;相关分析结果表明,老年食管癌根治术患者出院准备度与出院指导质量呈正相关,与疾病不确定感呈负相关,与社会支持水平呈正相关;多元回归分析结果显示,文化程度、合并症种类、营养状态、出院指导质量、疾病不确定感、社会支持是老年食管癌根治术患者出院准备度的影响因素。结论老年食管癌根治术患者出院准备度处于中等偏下水平,文化程度高、合并症种类少、营养状态好、出院指导质量好、疾病不确定感低、社会支持力度大的食管癌根治术患者出院准备度较高。医护人员需根据患者个体情况进行评估,制定有针对性、个性化、多元化的健康指导方案和出院准备计划,提升患者的出院准备度水平与院外生活质量。

微创McKeown食管癌根治术后疲劳综合征的相关危险因素分析

目的 探讨微创McKeown食管癌根治术后疲劳综合征(postoperative fatigue syndrome,POFS)的相关危险因素。方法 前瞻性收集2022年1月至2023年6月于南通市肿瘤医院行微创McKeown手术的80例食管癌患者的临床资料,依据围手术期疲劳评测量表(identity-consequence fatigue scale,ICFS)对纳入的患者实施术后疲劳状况的评估,然后将患者分为POFS组(n=34)和非POFS组(n=46)。通过电子病历收集两组患者的围手术期临床资料并进行单因素分析,最后采用多因素Logistic回归分析POFS的相关因素。结果 80例患者术后的ICFS总分为(82.21±6.64)分,显著高于术前的(57.34±4.11)分(P<0.05),且日常活动、精力、活力、注意力和疲劳维度5个维度评分也均显著高于术前(均P<0.05)。80例患者术后发生POFS为34例,发生率为42.50%。单因素分析显示,POFS组年龄显著大于非POFS组(P<0.05),POFS组术前合并焦虑或抑郁、睡眠障碍、低蛋白血症比例均显著高于非POFS组(均P<0.05),POFS组术前六分钟步行试验(6-minute walking test,6MWT)距离<350 m比例显著高于非POFS组(P<0.05),POFS组麻醉时间显著短于非POFS组(P<0.05),POFS组术后视觉模拟量评分法(visual analogue scale,VAS)评分、术后血清C反应蛋白(C-reactive protein,CRP)水平、术后乳酸水平均显著高于非POFS组(均P<0.05),POFS组术后血红蛋白(hemoglobin,Hb)水平显著低于非POFS组(P<0.05)。多因素Logistic回归分析显示,术前合并焦虑或抑郁、低蛋白血症、术前6MWT距离<350 m、麻醉时间短、术后血清CRP水平高均是微创McKeown食管癌根治术POFS发生的独立危险因素(均P<0.05)。结论 微创McKeown食管癌根治术后POFS发生率较高,且与术前焦虑抑郁情绪、低蛋白血症、6MWT距离过短、麻醉时间偏短和CRP水平偏高等因素密切相关,临床应重视此类危险因素并制订针对性的措施对其进行干预,以降低POFS发生率。

加速康复外科理念在胸腔镜肺癌根治术患者围术期的护理效果观察

目的观察加速康复外科理念在胸腔镜肺癌根治术患者围术期的护理效果。方法选取我院2021年1月至2023年1月收治的180例胸腔镜肺癌根治术患者,随机分为两组。对照组行常规护理,实验组在对照组基础上采用加速康复外科理念护理,比较两组的护理效果。结果护理后,实验组SAS、SDS评分低于对照组(P<0.05)。实验组首次下床时间、首次进食时间、胸腔引流管留置时间、平均住院时间短于对照组(P<0.05)。实验组并发症发生率为2.22%,低于对照组的16.67%(P<0.05)。结论加速康复外科理念护理可缓解胸腔镜肺癌根治术患者围术期负性情绪,缩短术后恢复时间及住院时间,降低并发症发生率。

Teach-back沟通模式结合疼痛管理在胸腔镜肺癌根治术后患者中的应用效果

目的:探讨Teach-back沟通模式结合疼痛管理在胸腔镜下肺癌根治术后患者中的应用效果。方法:选取2022年1—12月于广西医科大学附属肿瘤医院胸瘤外科行胸腔镜下肺癌根治术的412例患者作为研究对象,采用随机数表法将其分为观察组与对照组,各206例。对照组实施常规护理模式,观察组实施Teach-back沟通模式结合疼痛管理。比较两组疼痛程度、心境状态、自我效能感、癌因性疲乏状况及睡眠质量。结果:术后6 h、1 d、3 d,观察组疼痛数字评分法(NRS)评分均低于对照组,差异有统计学意义(P<0.05)。术后7 d,两组焦虑自评量表(SAS)、抑郁自评量表(SDS)评分均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。术后7 d,两组健康促进策略量表(SUPPH)中正性态度、自我决策、自我减压评分及总分均高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。术后7 d,两组Piper疲乏修正量表(PFS-R)中行为疲乏、情感疲乏、感觉疲乏、认知疲乏评分均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。术后7 d,两组匹兹堡睡眠指数量表(PSQI)评分均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。结论:Teach-back沟通模式结合疼痛管理有利于缓解胸腔镜下肺癌根治术患者疼痛程度、提升自我效能感,改善癌因性疲乏、心境状态及睡眠质量。