目的:探讨先兆流产患者保胎后不良妊娠结局的影响因素。方法:选取2020年7月至2023年2月本院收治的先兆流产患者96例为研究对象,均接受保胎治疗。依据治疗后妊娠结局情况分为良好组79例、不良组17例。分析比较两组临床资料。多因素Logis...目的:探讨先兆流产患者保胎后不良妊娠结局的影响因素。方法:选取2020年7月至2023年2月本院收治的先兆流产患者96例为研究对象,均接受保胎治疗。依据治疗后妊娠结局情况分为良好组79例、不良组17例。分析比较两组临床资料。多因素Logistic回归分析不良妊娠结局的影响因素。结果:孕产次数、流产次数、黄体功能不全、焦虑评分、宫内大血肿、尿完整型人绒毛膜促性腺激素(Intact human chorionic gonadotropin,I-HCG)/人绒毛膜促性腺激素相关蛋白(Human chorionic gonadotropin related protein,HCGRP)阳性2为不良妊娠结局的独立危险因素(P<0.05)。结论:孕产次数、流产次数、黄体功能不全、焦虑评分、宫内大血肿、尿I-HCG/HCGRP阳性2为先兆流产患者保胎后不良妊娠结局的高危因素。展开更多
To analyze how the multidisciplinary clinical, biohumoral, instrumental approach to ALTE (Apparent Life Threatening Event) episode may discover cardiovascular disease in the newborn. Introduction: In the first year of...To analyze how the multidisciplinary clinical, biohumoral, instrumental approach to ALTE (Apparent Life Threatening Event) episode may discover cardiovascular disease in the newborn. Introduction: In the first year of life ALTEs concern 0.8% of access to Pediatric Emergency Department. The cause of apparent life-threatening events (ALTEs) in infants reflects a differential diagnosis that includes an array of congenital or acquired disorders. Approximately 10% - 25% of ap-parent life-threatening events may remain unexplained following a thorough evaluation. Case re-port: B. E., a 2-month-old child, in wellbeing, shortly before meal, during sleep, was not responsive to repeated stimulations;he was hypotonic and unresponsive. About 15 minutes later, he pre-sented a normal tone and state of consciousness. Evaluating the referred symptoms, diagnostic protocol for ALTE was started;the Angio-MRI brain performed as second line analysis showed a focal gliotic lesion at left striatal area. The cardiological evaluation with echocardiography detected a pervium foramen ovale (PFO), with minimum shunt left-right direction. At least, biohumoral tests revealed protrombin gene heterozygosis mutation. Conclusion: Apparent Life-Threatening Events are first manifestation of stroke in infant. Discussion: This report discloses how the multidisciplinary clinical approach is essential in ALTE. The exact management of ALTE patients is very important in situations like this, when the concomitant disease is rare. In fact, arterial stroke incidence in children > 28 days of life is estimated between 1.2 and 7.9 cases/100,000 child-ren/year. However, in the last 20 years, we observed an increased incidence of stroke, probably related to two main causes: a greater attention for this disease and a major survival of children with pathology that arrange for stroke thanks to a better prevention. In conclusion, it’s a fundamental multidisciplinary approach even in following months after the events.展开更多
文摘目的:探讨先兆流产患者保胎后不良妊娠结局的影响因素。方法:选取2020年7月至2023年2月本院收治的先兆流产患者96例为研究对象,均接受保胎治疗。依据治疗后妊娠结局情况分为良好组79例、不良组17例。分析比较两组临床资料。多因素Logistic回归分析不良妊娠结局的影响因素。结果:孕产次数、流产次数、黄体功能不全、焦虑评分、宫内大血肿、尿完整型人绒毛膜促性腺激素(Intact human chorionic gonadotropin,I-HCG)/人绒毛膜促性腺激素相关蛋白(Human chorionic gonadotropin related protein,HCGRP)阳性2为不良妊娠结局的独立危险因素(P<0.05)。结论:孕产次数、流产次数、黄体功能不全、焦虑评分、宫内大血肿、尿I-HCG/HCGRP阳性2为先兆流产患者保胎后不良妊娠结局的高危因素。
文摘To analyze how the multidisciplinary clinical, biohumoral, instrumental approach to ALTE (Apparent Life Threatening Event) episode may discover cardiovascular disease in the newborn. Introduction: In the first year of life ALTEs concern 0.8% of access to Pediatric Emergency Department. The cause of apparent life-threatening events (ALTEs) in infants reflects a differential diagnosis that includes an array of congenital or acquired disorders. Approximately 10% - 25% of ap-parent life-threatening events may remain unexplained following a thorough evaluation. Case re-port: B. E., a 2-month-old child, in wellbeing, shortly before meal, during sleep, was not responsive to repeated stimulations;he was hypotonic and unresponsive. About 15 minutes later, he pre-sented a normal tone and state of consciousness. Evaluating the referred symptoms, diagnostic protocol for ALTE was started;the Angio-MRI brain performed as second line analysis showed a focal gliotic lesion at left striatal area. The cardiological evaluation with echocardiography detected a pervium foramen ovale (PFO), with minimum shunt left-right direction. At least, biohumoral tests revealed protrombin gene heterozygosis mutation. Conclusion: Apparent Life-Threatening Events are first manifestation of stroke in infant. Discussion: This report discloses how the multidisciplinary clinical approach is essential in ALTE. The exact management of ALTE patients is very important in situations like this, when the concomitant disease is rare. In fact, arterial stroke incidence in children > 28 days of life is estimated between 1.2 and 7.9 cases/100,000 child-ren/year. However, in the last 20 years, we observed an increased incidence of stroke, probably related to two main causes: a greater attention for this disease and a major survival of children with pathology that arrange for stroke thanks to a better prevention. In conclusion, it’s a fundamental multidisciplinary approach even in following months after the events.
