N′-（4-fluorobenzylidene）-2-（ 1H-1,2,4-triasole-1-yl） acetohydrazide was synthesized by the reaction of 4-flu- orobenzaldehyde with 2-（ 1H-1,2,4-triazole-1-yl） acetohydrazide. The structure was confirmed via ele...N′-（4-fluorobenzylidene）-2-（ 1H-1,2,4-triasole-1-yl） acetohydrazide was synthesized by the reaction of 4-flu- orobenzaldehyde with 2-（ 1H-1,2,4-triazole-1-yl） acetohydrazide. The structure was confirmed via elemental analysis, MS, ^1H NMR, IR, and X-ray diffraction. It crystallized in a monoclinic system with space group P2 （ 1 ）, α = 0.4905（1） nm, b =0. 8160（2） nm, c = 1.4105（3） nm, β =93. 33（3）°, Z=2, V=0.5636（2） nm^3, Do =1.457 Mg/m^3,μ =0. 112 mm^-1 , F（000） =256, and final R1 =0. 0685. Several intermolecular hydrogen-bond interactions existed in the crystal structure, facilitating the stabilization of the compound.展开更多
A typical nitroimine bistriazole（DNABT） was synthesized with high yield（90.4%） by nitration reaction from DABT in HNO3 and NH4NO3. Furthermore, a novel cocrystal（1） consisting of DNABT, H2O and DMSO in a 1：2：2...A typical nitroimine bistriazole（DNABT） was synthesized with high yield（90.4%） by nitration reaction from DABT in HNO3 and NH4NO3. Furthermore, a novel cocrystal（1） consisting of DNABT, H2O and DMSO in a 1：2：2 molar ratio was analysized on the crystal structure. Cocrystal 1 crystallizes in the triclinic system, space group P1 with a = 6.3124（18）, b = 8.233（2）, c = 9.775（3） A, β = 98.326（4）°, V = 481.59（74）A^3, Z = 2, Dc = 1.55 g/cm^3, F（000） = 234, μ = 0.337 mm^-1, S = 1.078, the final R = 0.0609 and w R = 0.2743. Additionally, the crystal structure is built up by four strong and seven weak hydrogen bonds. And the hydrogen bond network contributes to the stability of DNABT molecule. Typical TGA and DSC curves indicate the cocrystal 1 includes one endothermic and one exothermic decomposition processes, and the peak temperature at each process is 164.0 and 245.0 ℃. The nonisothermal decomposition kinetics analysis was performed by means of the Kissinger and Ozawa methods. The apparent activation energy（Ea） and pre-exponential factor（A） of the two decompositions are 96.0 kJ·mol^-1, 108.1 s^-1 and 215.8 kJ·mol^-1, 1018.9 s^-1, respectively.展开更多
The title compound, N′-(4-methoxybenzylidene)-2-(1%H%-1,2,4-triazol-1-yl)acetohydrazide, was synthesized and its structure was confirmed by means of IR, MS, 1H NMR and elemental analysis. The single crystal structure...The title compound, N′-(4-methoxybenzylidene)-2-(1%H%-1,2,4-triazol-1-yl)acetohydrazide, was synthesized and its structure was confirmed by means of IR, MS, 1H NMR and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test shows that the synthesized compound has a low antifungal activity.展开更多
The title compound, 2-（ 4-fluorophenyl ） -2-oxo-1-（ 1H-1, 2,4-triazol-1-yl ） ethyl morpholine-4-carbodithioate, was synthesized and its structure was confirmed by means of IR, MS, 1 H NMR and elemental analysis. T...The title compound, 2-（ 4-fluorophenyl ） -2-oxo-1-（ 1H-1, 2,4-triazol-1-yl ） ethyl morpholine-4-carbodithioate, was synthesized and its structure was confirmed by means of IR, MS, 1 H NMR and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test showed that the synthesized compound possesses some biological activities.展开更多
A series of ω-heterocyclyl-ω-(1H-1,2,4-triazol-1-yl) acetophenones have beensynthesized. All the compounds were characterized by elemental analysis and spectral data Thepreliminary biological test showed that some o...A series of ω-heterocyclyl-ω-(1H-1,2,4-triazol-1-yl) acetophenones have beensynthesized. All the compounds were characterized by elemental analysis and spectral data Thepreliminary biological test showed that some of them exhibited mild antifungal and plant growthregulative activities.展开更多
Eighteen novel triazole compounds containing 1,3,4-oxadiazole groups were synthesized from 2-（1H-1,2,4-triazol-1-yl）acetohydrazide and carbon disulfide by several step reactions. The target compounds were characteri...Eighteen novel triazole compounds containing 1,3,4-oxadiazole groups were synthesized from 2-（1H-1,2,4-triazol-1-yl）acetohydrazide and carbon disulfide by several step reactions. The target compounds were characterized by elemental analysis, 1H NMR, 13C NMR, IR, MS, and X-ray crystallography. The results of preliminary biological tests show that all the compounds exhibit certain fungicidal activities.展开更多
Seven novel triazole compounds containing 1,3-dithiolane groups were synthesized according to the biological isosterism. Their structures were confirmed by means of elemental analysis, MS, ^1H NMR, IR and X-ray crysta...Seven novel triazole compounds containing 1,3-dithiolane groups were synthesized according to the biological isosterism. Their structures were confirmed by means of elemental analysis, MS, ^1H NMR, IR and X-ray crystallography. The results of preliminary biological tests showed that all of these compounds possess some antifungal and plant growth regulatory activities.展开更多
文摘N′-（4-fluorobenzylidene）-2-（ 1H-1,2,4-triasole-1-yl） acetohydrazide was synthesized by the reaction of 4-flu- orobenzaldehyde with 2-（ 1H-1,2,4-triazole-1-yl） acetohydrazide. The structure was confirmed via elemental analysis, MS, ^1H NMR, IR, and X-ray diffraction. It crystallized in a monoclinic system with space group P2 （ 1 ）, α = 0.4905（1） nm, b =0. 8160（2） nm, c = 1.4105（3） nm, β =93. 33（3）°, Z=2, V=0.5636（2） nm^3, Do =1.457 Mg/m^3,μ =0. 112 mm^-1 , F（000） =256, and final R1 =0. 0685. Several intermolecular hydrogen-bond interactions existed in the crystal structure, facilitating the stabilization of the compound.
文摘A typical nitroimine bistriazole（DNABT） was synthesized with high yield（90.4%） by nitration reaction from DABT in HNO3 and NH4NO3. Furthermore, a novel cocrystal（1） consisting of DNABT, H2O and DMSO in a 1：2：2 molar ratio was analysized on the crystal structure. Cocrystal 1 crystallizes in the triclinic system, space group P1 with a = 6.3124（18）, b = 8.233（2）, c = 9.775（3） A, β = 98.326（4）°, V = 481.59（74）A^3, Z = 2, Dc = 1.55 g/cm^3, F（000） = 234, μ = 0.337 mm^-1, S = 1.078, the final R = 0.0609 and w R = 0.2743. Additionally, the crystal structure is built up by four strong and seven weak hydrogen bonds. And the hydrogen bond network contributes to the stability of DNABT molecule. Typical TGA and DSC curves indicate the cocrystal 1 includes one endothermic and one exothermic decomposition processes, and the peak temperature at each process is 164.0 and 245.0 ℃. The nonisothermal decomposition kinetics analysis was performed by means of the Kissinger and Ozawa methods. The apparent activation energy（Ea） and pre-exponential factor（A） of the two decompositions are 96.0 kJ·mol^-1, 108.1 s^-1 and 215.8 kJ·mol^-1, 1018.9 s^-1, respectively.
文摘The title compound, N′-(4-methoxybenzylidene)-2-(1%H%-1,2,4-triazol-1-yl)acetohydrazide, was synthesized and its structure was confirmed by means of IR, MS, 1H NMR and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test shows that the synthesized compound has a low antifungal activity.
文摘The title compound, 2-（ 4-fluorophenyl ） -2-oxo-1-（ 1H-1, 2,4-triazol-1-yl ） ethyl morpholine-4-carbodithioate, was synthesized and its structure was confirmed by means of IR, MS, 1 H NMR and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test showed that the synthesized compound possesses some biological activities.
文摘A series of ω-heterocyclyl-ω-(1H-1,2,4-triazol-1-yl) acetophenones have beensynthesized. All the compounds were characterized by elemental analysis and spectral data Thepreliminary biological test showed that some of them exhibited mild antifungal and plant growthregulative activities.
基金the National Natural Science Foundation of China(Nos.20771030 and 20671025)
文摘Eighteen novel triazole compounds containing 1,3,4-oxadiazole groups were synthesized from 2-（1H-1,2,4-triazol-1-yl）acetohydrazide and carbon disulfide by several step reactions. The target compounds were characterized by elemental analysis, 1H NMR, 13C NMR, IR, MS, and X-ray crystallography. The results of preliminary biological tests show that all the compounds exhibit certain fungicidal activities.
文摘Seven novel triazole compounds containing 1,3-dithiolane groups were synthesized according to the biological isosterism. Their structures were confirmed by means of elemental analysis, MS, ^1H NMR, IR and X-ray crystallography. The results of preliminary biological tests showed that all of these compounds possess some antifungal and plant growth regulatory activities.
