The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)information.In this paper,a 3D ISAR imaging method for the space target is propos...The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)information.In this paper,a 3D ISAR imaging method for the space target is proposed based on mutliorbit observation data and an improved orthogonal matching pursuit(OMP)algorithm.Firstly,the 3D scattered field data is converted into a set of 2D matrix by stacking slices of the 3D data along the elevation direction dimension.Then,an improved OMP algorithm is applied to recover the space target's amplitude information via the 2D matrix data.Finally,scattering centers can be reconstructed with specific three dimensional locations.Numerical simulations are provided to demonstrate the effectiveness and superiority of the proposed 3D imaging method.展开更多
Three dimensional(3D) displacements, which can be translated further into 3D strain, are key parameters tor design, manufacturing and quality control. Using different optical setups, phase-shift methods, and algorit...Three dimensional(3D) displacements, which can be translated further into 3D strain, are key parameters tor design, manufacturing and quality control. Using different optical setups, phase-shift methods, and algorithms, several different 3D electronic speckle pattern interferometry(ESPl) systems for displacement and strain measurements have been achieved and commercialized. This paper provides a review of the recent developments in ESPI systems for 3D displacement and strain measurement. After an overview of the fundamentals of ESP! theory, temporal phase-shift, and spatial phase-shift techniques, 3D deformation measurements by the temporal phase-shift ESPI system, which is suited well for static measurement, and by the spatial phase-shift ESPI system, which is particularly useful for dynamic measurement, are discussed. For each method, the basic theory, a brief derivation and different optical layouts are presented. The state of art application, potential and limitation of the ESPI systems are shown and demonstrated.展开更多
According to the latest data of geological structure, geophysics, in-situ stress measurement and focal mechanism,3-D tectonic stress field model in North China is built and 3-D tectonic stress field pattern of North C...According to the latest data of geological structure, geophysics, in-situ stress measurement and focal mechanism,3-D tectonic stress field model in North China is built and 3-D tectonic stress field pattern of North China aresimulated by finite element method. Then the overall characteristics and regional specific feature of North Chinaare studied. Finally, the influences of the valid dynamic boundary conditions of North China Block, active faultsand the inhomogeneity of crustal medium on tectonic stress field of North China are investigated.展开更多
The use of three dimensional in vitro systems in cancer research is a promising path for developing effective anticancer therapies.The aim of this study was to engineer a functional 3-D in vitro model of normal and ca...The use of three dimensional in vitro systems in cancer research is a promising path for developing effective anticancer therapies.The aim of this study was to engineer a functional 3-D in vitro model of normal and cancerous cervical tissue.Normal epithelial and immortalized cervical epithelial carcinoma cell lines were used to construct 3-D artificial normal cervical and cervical cancerous tissues.De-epidermised dermis(DED) was used as a scaffold for both models.Morphological analyses were conducted by using hematoxylin and eosin staining and characteristics of the models were studied by analyzing the expression of different structural cytokeratins and differential protein marker MAX dimerisation protein 1(Mad1) using immunohistochemical technique.Haematoxylin and eosin staining results showed that normal cervical tissue had multi epithelial layers while cancerous cervical tissue showed dysplastic changes.Immunohistochemistry staining revealed that for normal cervix model cytokeratin 10 was expressed in the upper stratified layer of the epithelium while cytokeratin 5 was expressed mainly in the middle and basal layer.Cytokeratin 19 was weakly expressed in a few basal cells.Cervical cancer model showed cytokeratin 19 expression in different epithelial layers and weak or no expression for cytokeratin 5 and cytokeratin 10.Madl expression was detected in some suprabasal cells.The 3-D in vitro models showed stratified epithelial layers and expressed the same types and patterns of differentiation marker proteins as seen in corresponding in vivo tissue in either normal cervical or cervical cancerous tissue.These findings imply that they can serve as functional normal and cervical cancer models.展开更多
BACKGROUND Floating thrombus within the thoracic aorta is a rare entity but may cause systemic embolism.The pathogenesis of floating aortic thrombi is not yet fully understood.No definitive guidelines are available fo...BACKGROUND Floating thrombus within the thoracic aorta is a rare entity but may cause systemic embolism.The pathogenesis of floating aortic thrombi is not yet fully understood.No definitive guidelines are available for the management of floating aortic thrombus.CASE SUMMARY We report a 48-year-old patient,without a history of trauma and infection,who presented with sudden severe back pain.A floating thrombus within the aortic arch was found by computed tomography angiography(CTA).No evidence of coagulopathies was found.However,with the assistance of a three dimensionalprinted model,this floating thrombus was identified to be caused by occult aortic dissection(AD).Subsequently,an emergency thoracic endovascular repair was performed.The patient’s back pain was rapidly alleviated postoperatively.CTA at 1 year showed no filling defect in the stent-graft and aorta.CONCLUSION Occult AD is a potential factor causing floating aortic thrombi,endovascular stent-graft exclusion may be an optimal therapeutic choice with promising results.Moreover,the combination of CTA and three dimensional-printed models can contribute to the diagnosis and treatment of floating aortic thrombi due to occult AD.展开更多
The primary objective of this article is to explore effects of latest development in the area of three dimensional(3D)printing&to assess its abilities,and further undertake helpful reporting.Here the focus is to a...The primary objective of this article is to explore effects of latest development in the area of three dimensional(3D)printing&to assess its abilities,and further undertake helpful reporting.Here the focus is to assess ad vantages of 3D printing in orthopedics and analyze how 3D printed models help solve complex 3D orthopedics distortions.This study identified that 3D models manufactured by 3D printing models reduce medical parts de velopment cost and surgical planning time.Integrating 3D printing with orthopaedics helps in understanding the conditions of problems and achieving the operation succssfully.This technology can enable doctors/surgeons to design,produce,recreate and plan operations more accurately,carefully,and economicaly.3D models can assist specialists with a visual comprehension of the patient-particular pathology and life structures.Innovation in 3D printing initiated a scaffold for the virtual outline and execution of medical procedures.This research proposes the utilisation of 3D printers as an elective procedure for the fabrication of parts.It empowers surgeons/patients for better raining,education and research.In the future,there is a foreseeable expansion of additive manufacturing in orthopedics.展开更多
In this paper, based on the random characteristic analysis of Tianjin Hospital earthquake waves of Tangshan aftershock, the three dimensional acceleration power spectrum density ratio has been presented.
This paper introduces a new three dimensional autonomous system with five equilibrium points. It demonstrates complex chaotic behaviours within a wide range of parameters, which are described by phase portraits, Lyapu...This paper introduces a new three dimensional autonomous system with five equilibrium points. It demonstrates complex chaotic behaviours within a wide range of parameters, which are described by phase portraits, Lyapunov exponents, frequency spectrum, etc. Analysis of the bifurcation and Poincar@ map is used to reveal mechanisms of generating these complicated phenomena. The corresponding electronic circuits are designed, exhibiting experimental chaotic attractors in accord with numerical simulations. Since frequency spectrum analysis shows a broad frequency bandwidth, this system has perspective of potential applications in such engineering fields as secure communication.展开更多
An ultraviolet(UV) curable support material pre-polymer for three dimensional printing was prepared based on the synergistic effect between PEO-PPO-PEO tri-block copolymer(F127) and polyethylene glycol (400) di-...An ultraviolet(UV) curable support material pre-polymer for three dimensional printing was prepared based on the synergistic effect between PEO-PPO-PEO tri-block copolymer(F127) and polyethylene glycol (400) di-acrylate(SR344). The effects of jetting conditions, thermal stability, curing time, mechanical properties and shrinking rate on printing models were studied. The situation of removing support material from build model was investigated after building progress was completed. The experimental result shows that when F127 is 6.0wt%, SR344 is 20.0wt%, 4-Methoxy phenol is 0.15wt% and Irgacure 2959 is 1.5wt%, the support material pre-polymer could be jetted out from the nozzles smoothly during building up of three dimensional printing models at 50-55 ℃. In addition, the support material could be removed easily from building model without spoiling the model; furthermore, the forming precision of building model is improved.展开更多
In this paper a series of digital image processing methods were adopted for getting separated coarse aggregates from asphalt mixture specimen using high-resolution X-ray Computed Tomography (CT) images.The existing th...In this paper a series of digital image processing methods were adopted for getting separated coarse aggregates from asphalt mixture specimen using high-resolution X-ray Computed Tomography (CT) images.The existing three dimensional (3D) particles matching methods based on two dimensional (2D) continuous cross-sections were analyzed and a new 'overlap area method' was presented.After the 3D particles were extracted one by one successfully,the basic parameters of each aggregate:perimeter,area,surface area,and volume were calculated by chain code method.Finally,the 3D mass center coordinates and the sphericity index were introduced.展开更多
Contribution:This paper designs a learning and training platform that can systematically help radiologists learn automated medical image analysis technology.The platform can help radiologists master deep learning theo...Contribution:This paper designs a learning and training platform that can systematically help radiologists learn automated medical image analysis technology.The platform can help radiologists master deep learning theories and medical applications such as the three-dimensional medical decision support system,and strengthen the teaching practice of deep learning related courses in hospitals,so as to help doctors better understand deep learning knowledge and improve the efficiency of auxiliary diagnosis.Background:In recent years,deep learning has been widely used in academia,industry,andmedicine.An increasing number of companies are starting to recruit a large number of professionals in the field of deep learning.Increasing numbers of colleges and universities also offer courses related to deep learning to help radiologists learn automated medical image analysis techniques.For now,however,there is no practical training platform that can help radiologists learn automated medical image analysis systematically.ApplicationDesign:The platform proposes the basic learning,model combat,business application(BMR)concept,including the learning guidance system and the assessment training system,which constitutes a closed-loop learning guidance mode of“learning-assessment-training-learning”.Findings:The survey results show that most of radiologists met their learning expectations by using this platform.The platform can help radiologists master deep learning techniques quickly,comprehensively and firmly.展开更多
A novel three dimensional network complex polymer [Cu_4(oxen)_2(N_3)_3]_n(ClO_4)_n·2nH_2O, where oxen is N,N' -bis(2-aminoethyl)oxamide dianion, has been synthesized. It crystallizes in triclinic system, spac...A novel three dimensional network complex polymer [Cu_4(oxen)_2(N_3)_3]_n(ClO_4)_n·2nH_2O, where oxen is N,N' -bis(2-aminoethyl)oxamide dianion, has been synthesized. It crystallizes in triclinic system, space group P, with a=11.486(2), b=11.706(3), c=12.291(3) , α=77.42(2), β=67.59(2), γ=77.96(2)°, and z=2. The least-square refinements converged at R=0.047, with 3416 observed unique reflections. The complex has a pronounced three-dimensional character and can be viewed as the tetranuclear asymmetric repeating units through inversion and translation operations to extend a three-dimensional network. The structure of Cu_4 asymmetric unit consists of two square planar and two square pyramidal Cu central atoms linked by both azide ligands in end-on and end-to-end bonding modes, and oxamidate bridge in trans conformation.展开更多
The variation principle is discussed and Rayleigh-Ritz method is proposed for construction of veloci ty field. A kinematically admissible velocity field based on polynomials was appIied to the determina tion of forgin...The variation principle is discussed and Rayleigh-Ritz method is proposed for construction of veloci ty field. A kinematically admissible velocity field based on polynomials was appIied to the determina tion of forging load and deformed buIge profile during upset forging of blocks. Simulation of upsetforging of rectangular blocks under various friction condjtions was performed. Comparison of the computed results with experiments and FEM shows good agreement. It is shown that this techniquecan be used for 3D simulation of metal forming process.展开更多
In this paper, a new analytical-engineering method of closed form solution about stress intensity factors for three dimensional finite bodies with eccentric cracks is derived by means of energy release rate method. Th...In this paper, a new analytical-engineering method of closed form solution about stress intensity factors for three dimensional finite bodies with eccentric cracks is derived by means of energy release rate method. The results of stress intensity factors can be obtained. The results provided ir this method are in nice agreement with those of the famous alternating method by which only special cases can be solved.展开更多
We have presented a three dimensional optical protein chip that fulfills the demanding for point-of-care diagnostics in terms of ease-of-use (one step assay), miniaturization (5 μl). The artful combination of magneti...We have presented a three dimensional optical protein chip that fulfills the demanding for point-of-care diagnostics in terms of ease-of-use (one step assay), miniaturization (5 μl). The artful combination of magnetic nanoparticles on chip and total internal reflection imaging (TIRI) technology permits the sensitive and rapid detection of hs-CRP (high-sensitivity C-reactive protein). The whole test was complete within 10 min using “all in one step” assay with a limit of detection of 0.1 ng/mL hs-CRP. The measuring range for hs-CRP could be extended to 10 ng/mL. The chip can also be used to detect more parameters in blood samples.展开更多
Part orientation is one of the important factors in manufacturing with three dimensional printing (3DP) of rapid prototyping system. The minimum building time, being achieved by the part’s minimum building height and...Part orientation is one of the important factors in manufacturing with three dimensional printing (3DP) of rapid prototyping system. The minimum building time, being achieved by the part’s minimum building height and minimum width in 3DP’s y direction, is set as the objective of optimizing the part orientation. Genetic algorithm is adopted to find the minimum building height of parts and then ergodic searching is used to get the minimum width of part in y direction. A corresponding program for optimizing part orientation in 3DP was developed. Tests show the proposed approach is effective and fast.展开更多
Three dimensional dynamic stress intensity factors are analyzed for a curved crack with a second order perturbation method. The method is extended to obtain an approximate representation of a three dimensional dynamic...Three dimensional dynamic stress intensity factors are analyzed for a curved crack with a second order perturbation method. The method is extended to obtain an approximate representation of a three dimensional dynamic stress intensity factors at the tip of a curved crack. Due to three dimensional curved crack growth the dynamic energy release rate can be calculated by using the Irwin's formula. A three dimensional curved crack in materials with inhomogeneous fracture toughness are considered. Paths of a brittle three dimensional curved crack propagating along a welded joint are predicted via the present method, where the effects of dynamic applied stresses, residual stresses, and material deterioration due to welding are taken into considerations.展开更多
Load transformation from the yielding part of the soil to the adjacent part is known as the soil arching effect,which plays an important role in the design of various geotechnical infrastructures.Terzaghi’s trapdoor ...Load transformation from the yielding part of the soil to the adjacent part is known as the soil arching effect,which plays an important role in the design of various geotechnical infrastructures.Terzaghi’s trapdoor test was an importantmilestone in the development of theories on soil arching.The research on earth pressure of the trapdoor problem is presented in this paper using the three-dimensional(3D)discrete element method(DEM).Five 3D trapdoor models with different heights are established by 3DDEMsoftware PFC 3D.The variation of earth pressure on the trapdoor with the downward movement of the trapdoor,the distribution of vertical earth pressure along the horizontal direction,the distribution of vertical earth pressure along the vertical direction,the distribution of lateral earth pressure coefficient along the depth direction,the magnitude and direction of contact force chain are studied,respectively.Related research results show that the earth pressure on the trapdoor decreases rapidly after the downward movement of the trapdoor,and then reaches the minimum earth pressure.After that,the earth’s pressure will rise slightly,and whether this phenomenon occurs depends on the depth ratio.For the bottom soil,due to the stress transfer caused by the soil arching effect,the ratio of earth pressure in the loose area decreases,while the ratio of earth pressure in the stable area increases.With the trapdoor moving down,the vertical earth pressure along the depth in the stable zone is basically consistent with the initial state,which shows an approximate linear distribution.After the trapdoor moves down,the distribution of earth pressure along with the depth in the loose area changes,which is far less than the theoretical value of vertical earth pressure of its self-weight.Because of the compression of the soil on both sides,the lateral earth pressure coefficient of most areas on the central axis of the loose zone is close to the passive earth pressure coefficient Kp.The existence of a‘soil arch’can be observed intuitively from the distribution diagram of the contact force chain in the loose zone.展开更多
Monte Carlo simulations are frequently utilized in radiation dose assessments.However,many researchers find the prevailing computing platforms to be intricate.This highlights a pressing need for a specialized framewor...Monte Carlo simulations are frequently utilized in radiation dose assessments.However,many researchers find the prevailing computing platforms to be intricate.This highlights a pressing need for a specialized framework for phantom dose evalua-tion.To address this gap,we developed a user-friendly radiation dose assessment platform using the Monte Carlo toolkit,Geant4.The Tsinghua University Phantom Dose(THUDosePD)augments the flexibility of Monte Carlo simulations in dosi-metric research.Originating from THUDose,a code with generic,functional,and application layers,THUDosePD focuses predominantly on anatomical phantom dose assessment.Additionally,it enables medical exposure simulation,intricate geometry creation,and supports both three-dimensional radiation dose analysis and phantom format transformations.The system operates on a multi-threaded parallel CPU architecture,with some modules enhanced for GPU parallel computing.Benchmark tests on the ICRP reference male illustrated the capabilities of THUDosePD in phantom dose assessment,covering the effective dose,three-dimensional dose distribution,and three-dimensional organ dose.We also conducted a voxelization conversion on the polygon mesh phantom,demonstrating the method’s efficiency and consistency.Extended applications based on THUDosePD further underline its broad adaptability.This intuitive,three-dimensional platform stands out as a valuable tool for phantom radiation dosimetry research.展开更多
文摘The conventional two dimensional(2D)inverse synthetic aperture radar(ISAR)imaging fails to provide the targets'three dimensional(3D)information.In this paper,a 3D ISAR imaging method for the space target is proposed based on mutliorbit observation data and an improved orthogonal matching pursuit(OMP)algorithm.Firstly,the 3D scattered field data is converted into a set of 2D matrix by stacking slices of the 3D data along the elevation direction dimension.Then,an improved OMP algorithm is applied to recover the space target's amplitude information via the 2D matrix data.Finally,scattering centers can be reconstructed with specific three dimensional locations.Numerical simulations are provided to demonstrate the effectiveness and superiority of the proposed 3D imaging method.
基金supported by National Natural Science Foundation of China(Grant Nos.51275054,51075116)
文摘Three dimensional(3D) displacements, which can be translated further into 3D strain, are key parameters tor design, manufacturing and quality control. Using different optical setups, phase-shift methods, and algorithms, several different 3D electronic speckle pattern interferometry(ESPl) systems for displacement and strain measurements have been achieved and commercialized. This paper provides a review of the recent developments in ESPI systems for 3D displacement and strain measurement. After an overview of the fundamentals of ESP! theory, temporal phase-shift, and spatial phase-shift techniques, 3D deformation measurements by the temporal phase-shift ESPI system, which is suited well for static measurement, and by the spatial phase-shift ESPI system, which is particularly useful for dynamic measurement, are discussed. For each method, the basic theory, a brief derivation and different optical layouts are presented. The state of art application, potential and limitation of the ESPI systems are shown and demonstrated.
文摘According to the latest data of geological structure, geophysics, in-situ stress measurement and focal mechanism,3-D tectonic stress field model in North China is built and 3-D tectonic stress field pattern of North China aresimulated by finite element method. Then the overall characteristics and regional specific feature of North Chinaare studied. Finally, the influences of the valid dynamic boundary conditions of North China Block, active faultsand the inhomogeneity of crustal medium on tectonic stress field of North China are investigated.
基金supported by the Middlesex University,particularly in the award of a Postgraduate Research Studentship that provided the necessary financial support for this research
文摘The use of three dimensional in vitro systems in cancer research is a promising path for developing effective anticancer therapies.The aim of this study was to engineer a functional 3-D in vitro model of normal and cancerous cervical tissue.Normal epithelial and immortalized cervical epithelial carcinoma cell lines were used to construct 3-D artificial normal cervical and cervical cancerous tissues.De-epidermised dermis(DED) was used as a scaffold for both models.Morphological analyses were conducted by using hematoxylin and eosin staining and characteristics of the models were studied by analyzing the expression of different structural cytokeratins and differential protein marker MAX dimerisation protein 1(Mad1) using immunohistochemical technique.Haematoxylin and eosin staining results showed that normal cervical tissue had multi epithelial layers while cancerous cervical tissue showed dysplastic changes.Immunohistochemistry staining revealed that for normal cervix model cytokeratin 10 was expressed in the upper stratified layer of the epithelium while cytokeratin 5 was expressed mainly in the middle and basal layer.Cytokeratin 19 was weakly expressed in a few basal cells.Cervical cancer model showed cytokeratin 19 expression in different epithelial layers and weak or no expression for cytokeratin 5 and cytokeratin 10.Madl expression was detected in some suprabasal cells.The 3-D in vitro models showed stratified epithelial layers and expressed the same types and patterns of differentiation marker proteins as seen in corresponding in vivo tissue in either normal cervical or cervical cancerous tissue.These findings imply that they can serve as functional normal and cervical cancer models.
基金Sichuan Foundation of Science and Technology,No.2019YJ0066Sichuan Foundation of Science and Technology,No.2019YFS0346.
文摘BACKGROUND Floating thrombus within the thoracic aorta is a rare entity but may cause systemic embolism.The pathogenesis of floating aortic thrombi is not yet fully understood.No definitive guidelines are available for the management of floating aortic thrombus.CASE SUMMARY We report a 48-year-old patient,without a history of trauma and infection,who presented with sudden severe back pain.A floating thrombus within the aortic arch was found by computed tomography angiography(CTA).No evidence of coagulopathies was found.However,with the assistance of a three dimensionalprinted model,this floating thrombus was identified to be caused by occult aortic dissection(AD).Subsequently,an emergency thoracic endovascular repair was performed.The patient’s back pain was rapidly alleviated postoperatively.CTA at 1 year showed no filling defect in the stent-graft and aorta.CONCLUSION Occult AD is a potential factor causing floating aortic thrombi,endovascular stent-graft exclusion may be an optimal therapeutic choice with promising results.Moreover,the combination of CTA and three dimensional-printed models can contribute to the diagnosis and treatment of floating aortic thrombi due to occult AD.
文摘The primary objective of this article is to explore effects of latest development in the area of three dimensional(3D)printing&to assess its abilities,and further undertake helpful reporting.Here the focus is to assess ad vantages of 3D printing in orthopedics and analyze how 3D printed models help solve complex 3D orthopedics distortions.This study identified that 3D models manufactured by 3D printing models reduce medical parts de velopment cost and surgical planning time.Integrating 3D printing with orthopaedics helps in understanding the conditions of problems and achieving the operation succssfully.This technology can enable doctors/surgeons to design,produce,recreate and plan operations more accurately,carefully,and economicaly.3D models can assist specialists with a visual comprehension of the patient-particular pathology and life structures.Innovation in 3D printing initiated a scaffold for the virtual outline and execution of medical procedures.This research proposes the utilisation of 3D printers as an elective procedure for the fabrication of parts.It empowers surgeons/patients for better raining,education and research.In the future,there is a foreseeable expansion of additive manufacturing in orthopedics.
文摘In this paper, based on the random characteristic analysis of Tianjin Hospital earthquake waves of Tangshan aftershock, the three dimensional acceleration power spectrum density ratio has been presented.
基金supported by the National Natural Science Foundation of China (Grant No. 10771088)Natural Science Foundation of Jiangsu Province,China (Grant No. 2007098)+3 种基金Outstanding Personnel Program in Six Fields of Jiangsu Province,China (Grant No. 6-A-029)National Natural Science (Youth) Foundation of China (Grant No. 10801140)Youth Foundation of Chongqing Normal University,China (Grant No. 08XLQ04)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China (Grant No. 09B 202Z)
文摘This paper introduces a new three dimensional autonomous system with five equilibrium points. It demonstrates complex chaotic behaviours within a wide range of parameters, which are described by phase portraits, Lyapunov exponents, frequency spectrum, etc. Analysis of the bifurcation and Poincar@ map is used to reveal mechanisms of generating these complicated phenomena. The corresponding electronic circuits are designed, exhibiting experimental chaotic attractors in accord with numerical simulations. Since frequency spectrum analysis shows a broad frequency bandwidth, this system has perspective of potential applications in such engineering fields as secure communication.
基金Funded by National High-tech Research and Development Projects of China(No. 2002AA6Z3083)
文摘An ultraviolet(UV) curable support material pre-polymer for three dimensional printing was prepared based on the synergistic effect between PEO-PPO-PEO tri-block copolymer(F127) and polyethylene glycol (400) di-acrylate(SR344). The effects of jetting conditions, thermal stability, curing time, mechanical properties and shrinking rate on printing models were studied. The situation of removing support material from build model was investigated after building progress was completed. The experimental result shows that when F127 is 6.0wt%, SR344 is 20.0wt%, 4-Methoxy phenol is 0.15wt% and Irgacure 2959 is 1.5wt%, the support material pre-polymer could be jetted out from the nozzles smoothly during building up of three dimensional printing models at 50-55 ℃. In addition, the support material could be removed easily from building model without spoiling the model; furthermore, the forming precision of building model is improved.
基金Sponsored by the Key Projects of National Natural Science Foundation of China (Grant No.51038004)the Western China Communications Construction and Technology Project (Grant No.2009318000078)
文摘In this paper a series of digital image processing methods were adopted for getting separated coarse aggregates from asphalt mixture specimen using high-resolution X-ray Computed Tomography (CT) images.The existing three dimensional (3D) particles matching methods based on two dimensional (2D) continuous cross-sections were analyzed and a new 'overlap area method' was presented.After the 3D particles were extracted one by one successfully,the basic parameters of each aggregate:perimeter,area,surface area,and volume were calculated by chain code method.Finally,the 3D mass center coordinates and the sphericity index were introduced.
基金This work is supported in part by the Major Fundamental Research of Natural Science Foundation of Shandong Province under Grant ZR2019ZD05Joint Fund for Smart Computing of Shandong Natural Science Foundation under Grant ZR2020LZH013+1 种基金the Scientific Research Platform and Projects of Department of Education of Guangdong Province under Grant 2019GKQNCX121the Intelligent Perception and Computing Innovation Platform of the Shenzhen Institute of Information Technology under Grant PT2019E001.
文摘Contribution:This paper designs a learning and training platform that can systematically help radiologists learn automated medical image analysis technology.The platform can help radiologists master deep learning theories and medical applications such as the three-dimensional medical decision support system,and strengthen the teaching practice of deep learning related courses in hospitals,so as to help doctors better understand deep learning knowledge and improve the efficiency of auxiliary diagnosis.Background:In recent years,deep learning has been widely used in academia,industry,andmedicine.An increasing number of companies are starting to recruit a large number of professionals in the field of deep learning.Increasing numbers of colleges and universities also offer courses related to deep learning to help radiologists learn automated medical image analysis techniques.For now,however,there is no practical training platform that can help radiologists learn automated medical image analysis systematically.ApplicationDesign:The platform proposes the basic learning,model combat,business application(BMR)concept,including the learning guidance system and the assessment training system,which constitutes a closed-loop learning guidance mode of“learning-assessment-training-learning”.Findings:The survey results show that most of radiologists met their learning expectations by using this platform.The platform can help radiologists master deep learning techniques quickly,comprehensively and firmly.
文摘A novel three dimensional network complex polymer [Cu_4(oxen)_2(N_3)_3]_n(ClO_4)_n·2nH_2O, where oxen is N,N' -bis(2-aminoethyl)oxamide dianion, has been synthesized. It crystallizes in triclinic system, space group P, with a=11.486(2), b=11.706(3), c=12.291(3) , α=77.42(2), β=67.59(2), γ=77.96(2)°, and z=2. The least-square refinements converged at R=0.047, with 3416 observed unique reflections. The complex has a pronounced three-dimensional character and can be viewed as the tetranuclear asymmetric repeating units through inversion and translation operations to extend a three-dimensional network. The structure of Cu_4 asymmetric unit consists of two square planar and two square pyramidal Cu central atoms linked by both azide ligands in end-on and end-to-end bonding modes, and oxamidate bridge in trans conformation.
文摘The variation principle is discussed and Rayleigh-Ritz method is proposed for construction of veloci ty field. A kinematically admissible velocity field based on polynomials was appIied to the determina tion of forging load and deformed buIge profile during upset forging of blocks. Simulation of upsetforging of rectangular blocks under various friction condjtions was performed. Comparison of the computed results with experiments and FEM shows good agreement. It is shown that this techniquecan be used for 3D simulation of metal forming process.
文摘In this paper, a new analytical-engineering method of closed form solution about stress intensity factors for three dimensional finite bodies with eccentric cracks is derived by means of energy release rate method. The results of stress intensity factors can be obtained. The results provided ir this method are in nice agreement with those of the famous alternating method by which only special cases can be solved.
文摘We have presented a three dimensional optical protein chip that fulfills the demanding for point-of-care diagnostics in terms of ease-of-use (one step assay), miniaturization (5 μl). The artful combination of magnetic nanoparticles on chip and total internal reflection imaging (TIRI) technology permits the sensitive and rapid detection of hs-CRP (high-sensitivity C-reactive protein). The whole test was complete within 10 min using “all in one step” assay with a limit of detection of 0.1 ng/mL hs-CRP. The measuring range for hs-CRP could be extended to 10 ng/mL. The chip can also be used to detect more parameters in blood samples.
基金the Natural Science Foundation Hubei Province, China (2005ABA181)
文摘Part orientation is one of the important factors in manufacturing with three dimensional printing (3DP) of rapid prototyping system. The minimum building time, being achieved by the part’s minimum building height and minimum width in 3DP’s y direction, is set as the objective of optimizing the part orientation. Genetic algorithm is adopted to find the minimum building height of parts and then ergodic searching is used to get the minimum width of part in y direction. A corresponding program for optimizing part orientation in 3DP was developed. Tests show the proposed approach is effective and fast.
基金supported by National Natural Science Foundation of China(No.91016026)Henan Province Natural Science Foundation Subsidy Project(No.152300410003)
文摘Three dimensional dynamic stress intensity factors are analyzed for a curved crack with a second order perturbation method. The method is extended to obtain an approximate representation of a three dimensional dynamic stress intensity factors at the tip of a curved crack. Due to three dimensional curved crack growth the dynamic energy release rate can be calculated by using the Irwin's formula. A three dimensional curved crack in materials with inhomogeneous fracture toughness are considered. Paths of a brittle three dimensional curved crack propagating along a welded joint are predicted via the present method, where the effects of dynamic applied stresses, residual stresses, and material deterioration due to welding are taken into considerations.
基金supports from National Natural Science Foundation of China (NSFC Grant No.52008373)Natural Science Foundation of Zhejiang Province of China (No.Q22E080445)are greatly acknowledged.
文摘Load transformation from the yielding part of the soil to the adjacent part is known as the soil arching effect,which plays an important role in the design of various geotechnical infrastructures.Terzaghi’s trapdoor test was an importantmilestone in the development of theories on soil arching.The research on earth pressure of the trapdoor problem is presented in this paper using the three-dimensional(3D)discrete element method(DEM).Five 3D trapdoor models with different heights are established by 3DDEMsoftware PFC 3D.The variation of earth pressure on the trapdoor with the downward movement of the trapdoor,the distribution of vertical earth pressure along the horizontal direction,the distribution of vertical earth pressure along the vertical direction,the distribution of lateral earth pressure coefficient along the depth direction,the magnitude and direction of contact force chain are studied,respectively.Related research results show that the earth pressure on the trapdoor decreases rapidly after the downward movement of the trapdoor,and then reaches the minimum earth pressure.After that,the earth’s pressure will rise slightly,and whether this phenomenon occurs depends on the depth ratio.For the bottom soil,due to the stress transfer caused by the soil arching effect,the ratio of earth pressure in the loose area decreases,while the ratio of earth pressure in the stable area increases.With the trapdoor moving down,the vertical earth pressure along the depth in the stable zone is basically consistent with the initial state,which shows an approximate linear distribution.After the trapdoor moves down,the distribution of earth pressure along with the depth in the loose area changes,which is far less than the theoretical value of vertical earth pressure of its self-weight.Because of the compression of the soil on both sides,the lateral earth pressure coefficient of most areas on the central axis of the loose zone is close to the passive earth pressure coefficient Kp.The existence of a‘soil arch’can be observed intuitively from the distribution diagram of the contact force chain in the loose zone.
基金This work was supported by the National Natural Science Foundation of China(General Program)(Nos.12175114,U2167209)the Foundation of Key Laboratory of Metrology and Calibration Technology(No.JLKG2022001C001)+2 种基金the Platform Development foundation of China Institute for Radiation Protection(No.YP21030101)the National Key R&D Program of China(No.2021YFF0603600)the Tsinghua University Initiative Scientific Research Program(No.20211080081).
文摘Monte Carlo simulations are frequently utilized in radiation dose assessments.However,many researchers find the prevailing computing platforms to be intricate.This highlights a pressing need for a specialized framework for phantom dose evalua-tion.To address this gap,we developed a user-friendly radiation dose assessment platform using the Monte Carlo toolkit,Geant4.The Tsinghua University Phantom Dose(THUDosePD)augments the flexibility of Monte Carlo simulations in dosi-metric research.Originating from THUDose,a code with generic,functional,and application layers,THUDosePD focuses predominantly on anatomical phantom dose assessment.Additionally,it enables medical exposure simulation,intricate geometry creation,and supports both three-dimensional radiation dose analysis and phantom format transformations.The system operates on a multi-threaded parallel CPU architecture,with some modules enhanced for GPU parallel computing.Benchmark tests on the ICRP reference male illustrated the capabilities of THUDosePD in phantom dose assessment,covering the effective dose,three-dimensional dose distribution,and three-dimensional organ dose.We also conducted a voxelization conversion on the polygon mesh phantom,demonstrating the method’s efficiency and consistency.Extended applications based on THUDosePD further underline its broad adaptability.This intuitive,three-dimensional platform stands out as a valuable tool for phantom radiation dosimetry research.