Application of three-dimensional speckle tracking technique in measuring left ventricular myocardial function in patients with diabetes

BACKGROUND Diabetic cardiomyopathy is considered as a chronic complication of diabetes mellitus(DM).Therefore,early detection of left ventricular systolic function(LVSF)damage in DM is essential.AIM To explore the use of the three-dimensional speckle tracking technique(3D-STI)for measuring LVSF in DM patients via meta-analysis.METHODS The electronic databases were retrieved from the initial accessible time to 29 April 2023.The current study involved 9 studies,including 970 subjects.We carried out this meta-analysis to estimate myocardial function in DM compared with controls according to myocardial strain attained by 3D-STI.RESULTS Night articles including 970 subjects were included.No significant difference was detected in the left ventricular ejection fraction between the control and the diabetic group(P>0.05),while differences in global longitudinal strain,global circumferential strain,global radial strain,and global area strain were markedly different between the controls and DM patients(all P<0.05).CONCLUSION The 3D-STI could be applied to accurately measure early LVSF damage in patients with DM.

Left Ventricular Systolic Strain of the Cardiac Allograft Evaluated with Three-dimensional Speckle Tracking Echocardiography

Three-dimensional speckle tracking echocardiography was employed to evaluate the changes of left ventricular systolic strain in 23 heart transplant recipients at 1 st, 3rd, 6th and 12th month after heart transplantation, and 23 healthy subjects served as controls. The three-dimensional full-volume echocardiographic images of left ventricle were recorded and then were analyzed using EchoPAC software. The strain curves and peak systolic strain values for each segment and overall left ventricular wall were obtained. Left ventricular global peak longitudinal strain （GPSL）, global peak radial strain （GPSR）, global peak circumferential strain （GPSC） and global peak area strain （GPSA） were measured and then statistically analyzed. There were no significant differences in left ventricular ejection fraction （LVEF） and cardiac output （CO） between heart transplant recipients and controls. The GPSL in heart transplant recipients at 1st month after surgery was significantly lower than that in controls, but close to the normal value at 3rd month after surgery and later. The GPSC, GPSA and GPSR were significantly lower in heart transplant recipients at 1 st, 3rd, 6th and 12th month after surgery than those in controls. It is suggested that three-dimensional speckle tracking echocardiography can be used for monitoring changes of left ventricular systolic strains and evaluating left ventricular systolic function in cardiac allograft.

Assessment of Left Atrial Function by Full Volume Real-time Three-dimensional Echocardiography and Left Atrial Tracking in Essential Hypertension Patients with Different Patterns of Left Ventricular Geometric Models

Objective To evaluate left atrial function in essential hypertension patients with different patterns of left ventricular geometric models by real-time three-dimensional echocardiography （RT-3DE） and left atrial tracking （EAT）.

Three-dimensional mesoscale eddy identification and tracking algorithm based on pressure anomalies Liming

The Kuroshio Extension(KE)is one of the most eddy-energetic regions in the global ocean.However,most mesoscale eddy studies in the region are focused on surface eddies and the structure and characteristics of three-dimensional(3-D)eddies require additional research.In this study,we proposed a 3-D eddy identification and tracking algorithm based on pressure anomalies,similar to sea level anomalies(SLAs)for surface eddy identification.We applied this scheme to a 5-year(2008-2012)high-resolution numerical product to develop a 3-D eddy dataset in the KE.The reliability of the numerical product was verified by the 5-year temperature/salinity hydrological characteristics and surface eddy distribution.According to the 3-D eddy tracking dataset,the number of eddies decreased dramatically as the eddy existence-time increased and more anticyclonic eddies(AEs)had an existence-time longer than 1 week than cyclonic eddies(CEs).We presented daily variations in the 3-D structure of two 3-D eddy-tracking trajectories that exhibit a certain jump in depth and a shift toward the west and equator.In addition to the bowl,lens,and cone eddies that have been discovered by previous researchers,we found that there is a cylindrical eddy,and its eddy radii are almost consistent across all layers.CEs cause significant negative temperature anomalies,“negative-positive”salinity anomalies,and sinking current fields in the KE region,while AEs cause positive temperature anomalies,“positive-negative”salinity anomalies,and upward current fields.The four types of eddies have different effects on the temperature/salinity anomalies and current field distribution which are related to their structure.

Particle path tracking method in two- and three-dimensional continuously rotating detonation engines

The particle path tracking method is proposed and used in two-dimensional（2D） and three-dimensional（3D） numerical simulations of continuously rotating detonation engines（CRDEs）. This method is used to analyze the combustion and expansion processes of the fresh particles, and the thermodynamic cycle process of CRDE. In a 3D CRDE flow field, as the radius of the annulus increases, the no-injection area proportion increases, the non-detonation proportion decreases, and the detonation height decreases. The flow field parameters on the 3D mid annulus are different from in the 2D flow field under the same chamber size. The non-detonation proportion in the 3D flow field is less than in the 2D flow field. In the 2D and 3D CRDE, the paths of the flow particles have only a small fluctuation in the circumferential direction. The numerical thermodynamic cycle processes are qualitatively consistent with the three ideal cycle models, and they are right in between the ideal F–J cycle and ideal ZND cycle. The net mechanical work and thermal efficiency are slightly smaller in the 2D simulation than in the 3D simulation. In the 3D CRDE, as the radius of the annulus increases, the net mechanical work is almost constant, and the thermal efficiency increases. The numerical thermal efficiencies are larger than F–J cycle, and much smaller than ZND cycle.

Deep Energies for Estimating Three-Dimensional Facial Pose and Expression

While much progress has been made in capturing high-quality facial performances using motion capture markers and shape-from-shading,high-end systems typically also rely on rotoscope curves hand-drawn on the image.These curves are subjective and difficult to draw consistently;moreover,ad-hoc procedural methods are required for generating matching rotoscope curves on synthetic renders embedded in the optimization used to determine three-dimensional(3D)facial pose and expression.We propose an alternative approach whereby these curves and other keypoints are detected automatically on both the image and the synthetic renders using trained neural networks,eliminating artist subjectivity,and the ad-hoc procedures meant to mimic it.More generally,we propose using machine learning networks to implicitly define deep energies which when minimized using classical optimization techniques lead to 3D facial pose and expression estimation.

Three-dimensional neural network tracking control of autonomous underwater vehicles with input saturation

This paper addresses the problem of three-dimensional trajectory tracking control for underactuated autonomous underwater vehicles in the presence of parametric uncertainties,environmental disturbances and input saturation.First,a virtual guidance control strategy is established on the basis of tracking error kinematics,which resolves the overall control system into two cascade subsystems.Then,a first-order sliding mode differentiator is introduced in the derivation to avoid tedious analytic calculation,and a Gaussian error function-based continuous differentiable symmetric saturation model is explored to tackle the issue of input saturation.Combined with backstepping design techniques,the neural network control method and an adaptive control approach are used to estimate composite items of the unknown uncertainty and approximation errors.Meanwhile,Lyapunov-based stability analysis guarantees that control error signals of the closed-loop system are uniformly ultimately bounded.Finally,simulation studies are conducted for the trajectory tracking of a moving target and a spiral line to validate the effectiveness of the proposed controller.

Estimation of Three-Dimensional Volumetric Errors of Numerically Controlled Machine Tools by a Tracking Interferometer

This paper presents the estimation of three-dimensional volumetric errors of a machining center by using a tracking interferometer. A tracking interferometer is a laser interferometer with the mechanism to steer the laser direction to follow a target retroreflector. Based on the triangulation principle, the three-dimensional position of the target can be estimated from measured laser displacements. Its capability to measure three-dimensional positioning errors for arbitrary trajectories is important for the indirect measurement of the machine＇s kinematic model. This paper presents experimental investigation of the estimation accuracy of the multilateration-based measurement by a tracking interferometer. A tracking interferometer developed by a part of the authors is used in experiments. In the present experiment, the measured volume of target positions was 100 mm × 100 mm × 100 mm. The estimation accuracy of targets within this volume was not sufficiently high compared to the positioning error of the measured machine tool. The results of the experiment and simulation show that the estimation uncertainty is dependent on tracking interferometer locations relative to target locations. Error sensitivity analysis shows that wider distribution of tracker positions in XY improves the estimation accuracy.

Three-Dimensional Discrete Observability Analysis for Air-to-Air Missile Target Tracking

The interception information of infrared（ IR）-guided air-to-air missiles（ AAM） is mainly estimated only using the basic bearing measurements. In order to intercept highly maneuverable targets,it is essential to study the system observability to improve the target tracking system performance.The uniqueness of this paper is that the observability analysis is derived based on a discrete three-dimensional （3D） system model. During the maneuvering scenario,the system is approximated by a segment-by-segment system. The relationship between missile-target motion and observability is given by direct and dual approaches. Meanwhile sufficient observability conditions are derived. Moreover,a numerical simulation is conducted and an alternate method is provided to reinforce the proposed observability analysis results.

Value of myocardial function in children with Kawasaki disease by two-dimensional and three-dimensional ultrasound speckle tracking

Objective:To investigate the value of two-dimensional ultrasound speckle tracking(2D-STI)and three-dimensional ultrasound speckle tracking(3D-STI)in evaluating myocardial function in children with Kawasaki disease.Methods 92 children with Kawasaki disease admitted to our hospital from February 2017 to February 2019 were retrospectively analyzed.50 children who underwent 3D-STI examination were taken as observation group and 42 children who underwent 2D-STI examination were taken as control group.The left ventricular systolic function index,storage time and analysis time of the image,the diameter of coronary artery,the strain difference of left ventricular basal segment,middle segment,apical segment and whole segment were observed.Results The levels of left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular myocardial mass(LVMI)in the observation group were higher than those in the control group(P<0.05),but there was no statistical difference in left ventricular ejection fraction(LVEF)between the two groups(P>0.05).The storage time and analysis time of the image in the observation group were significantly lower than those in the control group(P<0.05).The left coronary artery(LCA)and right coronary artery(RCA)in the observation group were higher than those in the control group(P<0.05).There was no statistical difference between left anterior descending(LAD)in the two groups(P>0.05).The longitudinal peak systolic strain(LS),circumferential peak systolic strain(CS)and radial peak systolic strain(RS)in the observation group were higher than those in the control group(P<0.05).The global longitudinal peak strain(GLS),global circumferential peak strain(GCS)and global radial peak strain(GRS)in the observation group were higher than those in the control group(P<0.05).LS and CS in the middle segment of the observation group were higher than those in the control group(P<0.05).Conclusions Compared with 2D-STI,3D-STI can objectively and accurately reflect the myocardial function of children with Kawasaki disease.

Correlation between three-dimensional speckle tracking imaging parameter and the cardiotoxicity of chemotherapeutics in patients with lung cancer chemotherapy

Objective: To study the correlation between three-dimensional speckle tracking imaging (3D-STI) parameter global area strain (GAS) and the cardiotoxicity of chemotherapeutics in patients with lung cancer chemotherapy. Methods: Patients with lung cancer who underwent chemotherapy in the Second Affiliated Hospital of Xi'an Medical University between February 2016 and May 2017 were selected as the chemotherapy group, the healthy subjects who received physical examination during the same period were selected as the control group, the 3D-STI examination was performed and GAS was calculated;the serum was collected to determine the contents of cardiotoxicity markers as well as apoptosis and oxidative stress indexes, and the peripheral blood was collected to determine the expression of apoptosis and oxidative stress molecules. Results: GAS level, serum ALDH2 and CAT contents as well as peripheral blood Keap1 and Bcl-2 expression intensity of chemotherapy group were lower than those of control group whereas serum Copeptin, CK-MB, cTnI, cMyBP-c, sTWEAK, sFas, MDA and 8-isoPGF2α contents as well as peripheral blood Nrf-2, gp91phox, p22 phox and Caspase-3 expression intensity were significantly higher than those of control group;the GAS level in chemotherapy group was negatively correlated with serum Copeptin, CK-MB, cTnI, cMyBP-c, sTWEAK, sFas, MDA and 8-isoPGF2α contents as well as peripheral blood Nrf-2, gp91phox, p22 phox and Caspase-3 expression intensity, and positively correlated with serum ALDH2 and CAT contents as well as peripheral blood Keap1 and Bcl-2 expression intensity. Conclusion: The changes of 3D-STI parameter GAS in patients with lung cancer chemotherapy can reflect the degree of cardiotoxicity induced by oxidative stress and apoptosis.

Correlation between three-dimensional speckle tracking parameters and serum index changes during left ventricular remodeling in patients with coronary heart disease

Objective:To study the correlation between three-dimensional speckle tracking parameters and serum index changes during left ventricular remodeling in patients with coronary heart disease. Methods: Patients who were diagnosed with coronary heart disease and angina pectoris in our hospital between March 2015 and May 2017 were selected as the CHD group of the study, and the healthy subjects who received medical examination in our hospital during the same period were taken as the control group;the three-dimensional speckle tracking parameters, peripheral blood signal molecule expression as well as serum cytokine and collagen metabolism index levels of the two groups were measured.Results: GLS and AGS levels in CHD group were significantly lower than those in control group whereas GCS and GRS levels were not significantly different from those in control group, and peripheral blood Notch1, Hes1, NF-κB and PKC expression intensity as well as serum sTWEAK, FGF23, TGF-β1, GDF15, sSema4D, CaN, MMP14, PINP and ICTP contents were significantly higher than those of control group;GLS and AGS levels in CHD group were negatively correlated with peripheral blood Notch1, Hes1, NF-κB and PKC expression intensity as well as serum sTWEAK, FGF23, TGF-β1, GDF15, sSema4D, CaN, MMP14, PINP and ICTP contents.Conclusions:The changes of three-dimensional speckle tracking parameters GLS and AGS in patients with coronary heart disease are closely related to the changes in signal pathway function, cytokine secretion and collagen metabolism during left ventricular remodeling.

Three-dimensional multi-relaxation-time lattice Boltzmann front-tracking method for two-phase flow

We developed a three-dimensional multi-relaxation-time lattice Boltzmann method for incompressible and immiscible two-phase flow by coupling with a front-tracking technique. The flow field was simulated by using an Eulerian grid, an adaptive unstructured triangular Lagrangian grid was applied to track explicitly the motion of the two-fluid interface, and an indicator function was introduced to update accurately the fluid properties. The surface tension was computed directly on a triangular Lagrangian grid, and then the surface tension was distributed to the background Eulerian grid. Three benchmarks of two-phase flow, including the Laplace law for a stationary drop, the oscillation of a three-dimensional ellipsoidal drop, and the drop deformation in a shear flow, were simulated to validate the present model.

Track-MT3:一种基于Transformer的新型多目标跟踪算法

针对复杂环境中多目标跟踪数据关联难度大、难以实现目标长时间稳定跟踪的问题,该文创新性地提出了一种基于Transformer网络的端到端多目标跟踪模型Track-MT3。首先,引入了检测查询和跟踪查询机制,隐式地执行量测-目标的数据关联并且实现了目标的状态估计任务。然后,采用跨帧目标对齐策略增强跟踪轨迹的时间连续性。同时,设计了查询变换与时间特征编码模块强化目标运动建模能力。最后,在模型训练中采用了集体平均损失函数,实现了模型性能的全局优化。通过构造多种复杂的多目标跟踪场景,并利用多重性能指标进行评估,Track-MT3展现了优于MT3等基线方法的长时跟踪性能,与JPDA和MHT方法相比整体性能分别提高了6%和20%,能够有效挖掘时序信息,在复杂动态环境下实现稳定、鲁棒的多目标跟踪。

基于改进Tracktor的行人多目标跟踪算法

在多目标视频跟踪中,针对受交互遮挡等影响导致检测偏差从而致使目标身份丢失的问题,提出一种基于改进Tracktor的行人多目标跟踪算法DUTracktor。在检测框回归中设计一个动态更新模块,利用孪生网络对建议框进一步检测定位;利用时序信息增强模块更新当前帧更适合的模板,建立全局上下文关系;并通过像素相关进行特征融合,从而增强目标边缘信息和尺度信息;利用相机运动补偿和融合相似矩阵构建二级关联跟踪机制,建立检测框和轨迹更强大的关联性,提高目标跟踪的鲁棒性。在公开的MOT16数据集上进行实验测试,并与当前主流算法相比,该算法跟踪精度表现较优,具有良好的鲁棒性,FPS稳定在24帧。

BEVTrack:基于难例挖掘训练的端到端三维多目标跟踪方法

多目标跟踪已经成为自动驾驶系统中的一个关键组成部分,其目的是在连续的视频流与点云流中识别、定位并标识所有感兴趣的目标。目前三维多目标跟踪方法多依赖人工多阶段调参以保证整体跟踪性能,难以对复杂遮挡或运动进行有效建模。而现有的三维端到端多目标跟踪方法,如MUTR等,精度普遍较低。其核心原因为三维空间中的特征聚合和感知相对于二维图像更具挑战性,简单的网络难以实现复杂的三维特征聚合,并大量的噪声信息与难例信息干扰严重,影响模型的特征提取能力。针对以上问题,本文提出了一种基于难例挖掘训练的端到端多目标跟踪框架BEVTrack。针对三维特征关联问题,本文设计了基于鸟瞰图(BEV)位置编码的三维跟踪查询。通过基于BEV特征的三维跟踪查询,本文方法能够更好地将跟踪查询与实际三维特征进行有效关联,从而大幅度提升了跟踪精度。同时,模型依靠BEV数据进行特征关联,仅需轻量化的网络便可以实现快速有效的跟踪。针对数据噪声问题,本文提出了面向多目标跟踪的难例挖掘训练,通过针对检测难例与跟踪难例分别处理,训练模型去除检测错误噪声与跟踪匹配的能力,从而提升在真实场景下模型处理噪声信息与难例干扰的能力。在实验结果方面,基于Nuscenes数据集,我们进行了大量的对比实验与模型消融实验,实验结果证明本文的方法在该数据集上取得了领先的性能。

Numerical Simulation of Water Exchange Characteristics of the Jiaozhou Bay Based on A Three-Dimensional Lagrangian Model

Based on theory of three-dimensional hydrodynamics, an Euler-Lagrangian particle model is established to study the transport and water exchange capability in the Jiaozhou Bay. The three-dimensional hydrodynamic model, driven by tide and wind, is used to study the effects of wetting and drying of estuarine intertidal flats by the dry-wet grid technology based on the Estuarine, Coastal and Ocean Model （ECOM）. The particle model includes the advection and the diffusion processes, of which the advection process is simulated with a certain method, and the diffusion process is simulated with the random walk method. The effect of the intertidal zone, the turbulent diffusion and the timescales of the water exchange are also discussed. The results show that a moving boundary model can simulate the transport process of the particle in the intertidal zone, where the particles are transported for a longer distance than that of the stationary result. Simulations with and without the turbulent random walk show that the effect of turbulent diffusion is very effective at spreading particles throughout the estuary and speeding up the particle movement. The spatial distribution of residence time is given to quantify the water exchange capability that has very important ramifications to water quality. The effect of wind on the water exchange is also examined and the southeasterly wind in summer tends to block the water exchange near the northeast coast, while the northerly wind in winter speeds up the transport process. These results indicate that the Lagrangian particle model is applicable and has a large potential to help understanding the water exchange capability in estuaries, which can also be useful to simulate the transport process of contaminant.

Three-dimensional Computational Fluid Dynamics Modeling of Two-phase Flow in a Structured Packing Column

Characterizing the complex two-phase hydrodynamics in structured packed columns requires a power- ful modeling tool. The traditional two-dimensional model exhibits limitations when one attempts to model the de- tailed two-phase flow inside the columns. The present paper presents a three-dimensional computational fluid dy- namics （CFD） model to simulate the two-phase flow in a representative unit of the column. The unit consists of an CFD calculations on column packed with Flexipak 1Y were implemented within the volume of fluid （VOF） mathe- matical framework. The CFD model was validated by comparing the calculated thickness of liquid film with the available experimental data. Special attention was given to quantitative analysis of the effects of gravity on the hy- drodynamics. Fluctuations in the liquid mass flow rate and the calculated pressure drop loss were found to be quali- tatively in agreement with the experimental observations.

Three-Dimensional Tidal Model and Its Application to Numerical Simulation of Water Quality in Coastal Waters

The turbulence mechanism plays an important part in the mixing process and momentum transfer of turbulence. A three-dimensional Prandtl mixing length tidal model has been developed to simulate tidal flows and water quality. The eddy viscosities and diffusivities are computed from the Prandtl mixing length model. In order to model the water quality of an estuary or coastal area many interdependent processes need to be simulated. These may be conveniently separated into three main groups: transport and mixing processes, biochemical interaction of water quality variables and the utilization and re-cycling of nutrients by living matter. The model simulates full oxygen and nutrient balance, primary productivity and the transport, reaction mechanism and fate of pollutants over tidal time-scales. The model is applied to numerical simulation of tidal flows and water quality in Dalian Bay. The model has been calibrated against a limited data set of historical water quality observations and in general demonstrates excellent agreement with all available data.

Three-Dimensional and Cross-sectional Characteristics of Normal Grain Growth Based on Monte Carlo Simulation

An appropriate Monte Carlo method was developed to simulate the three-dimensional normal grain growth more completely. Comparative investigation on the three-dimensional and the cross-sectional characteristics of normal grain growth was done. It was found that the time exponent of grain growth determined from cross-section exhibits the same rule of increasing slowly with time and approaching the theoretical value n = 0.5 of steadygrain growth as the three-dimensional (3-D) system. From change of the number of grains per unit area with timemeasured in cross-section, the state of 3-D normal grain growth may be predicted. The gtain size distribution incross-section is different from that in 3-D system and can not express the evolution characteristic of the 3-D distribution. Furthermore, there exists statistical connection between the topological parameters in cross-section and thosein three-dimensions.