Three-dimensional displacement characteristics of adjacent pile induced by shield tunneling under influence of multiple factors

Shield tunneling inevitably passes through a large number of pile foundations in urban areas.Thus,an accurate assessment of tunneling-induced pile displacement and potential damage becomes a critical part of shield construction.This study presents a mechanism research of pile-soil-tunnel interaction through Pasternak-based two-stage analysis method.In the first stage,based on Mindlin’s solution,the soil displacement fields induced by shield thrust force,cutterhead frictions,shield shell frictions and grouting pressure are derived.The analytical solution of threedimensional soil displacement field is established by introducing Pinto’s three-dimensional volume loss formula,which solves the problems that shield construction factors are not taken into account in Loganathan’s formula and only twodimensional soil displacement field can be obtained.In the second stage,based on Pasternak’s two-parameter foundation model,the analytical solution of pile displacement induced by shield tunneling in layered soil is derived.A case was found in the project of interval tunnels from Wanjiali Square to Furong District Government of Changsha Metro Line 5,where the shield tunnels were constructed near viaduct piles.The reliability of the analytical solution proposed in this study is verified by comparing with the field measured data and the results of finite element method(FEM).In addition,the comparisons of longitudinal,horizontal and vertical displacements of soil and pile foundation analyzed by the analytical solution and FEM provide corresponding theoretical basis,which has significant engineering guidance for similar projects.

A modified moire interferometer for three-dimensional displacement measurement

This paper presents a new optical interferometric system, MMI-T/G, composed of a modified four-beam moire interferometer and a Twyman/Green interferometer. The MMI-T/G system can measure three-dimensional displacement fringe patterns with a single loading on the specimen, and the in-plane and out-of-plane displacement fields can be measured independently and defined clearly. The optical setup has the advantages of structural novelty, flexibility, and high fringe contrast. Moreover, the in-plane displacement sensitivity is twice of that of the normal moire interferometer. The measuring techniques to obtain the fringe patterns and displacement fields using the MMI-T/G system are described. The experimental results of thermal displacement of an electronic device are shown.

Effect of proximal contact strength on the three-dimensional displacements of implant-supported cantilever fixed partial dentures under axial loading

Objective:This study investigated the effect of proximal contact strength on the three-dimensional displacements of cantilever fixed partial denture(CFPD) under vertically concentrated loading with digital laser speckle(DLS) technique.Methods:Fresh mandible of beagle dog was used to establish the implant-supported CFPD for specimen.DLS technique was employed for measuring the three-dimensional displacement of the prosthesis under vertically concentrated loading ranging from 200 to 3 000 g.The effect of the contact tightness on the displacement of CFPD was investigated by means of changing the contact tightness.Results:When an axial concentrated loading was exerted on the pontic of the implant-supported CFPD,the displacement of the CFPD was the greatest.The displacement of the prosthesis decreased with the increase of contact strength.When the contact strength was 0,0.95,and 3.25 N,the displacement of the buccolingual direction was smaller than that of the mesiodistal direction but greater than that of the occlusogingival direction.When the force on the contact area was 6.50 N,the mesiodistal displacement of the prosthesis was the biggest while the buccolingual displacement was the smallest.Conclusions:The implant supported CFPD is an effective therapy for fully or partially edentulous patients.The restoration of the contact area and the selection of the appropriate contact strength can reduce the displacement of the CFPD,and get a better stress distribution.The most appropriate force value is 3.25 N in this study.

Autologous nerve graft repair of different degrees of sciatic nerve defect:stress and displacement at the anastomosis in a three-dimensional finite element simulation model

In the repair of peripheral nerve injury using autologous or synthetic nerve grafting, the mag- nitude of tensile forces at the anastomosis affects its response to physiological stress and the ultimate success of the treatment. One-dimensional stretching is commonly used to measure changes in tensile stress and strain; however, the accuracy of this simple method is limited. There- fore, in the present study, we established three-dimensional finite element models of sciatic nerve defects repaired by autologous nerve grafts. Using PRO E 5.0 finite element simulation software, we calculated the maximum stress and displacement of an anastomosis under a 5 N load in 10-, 20-, 30-, 40-mm long autologous nerve grafts. We found that maximum displacement increased with graft length, consistent with specimen force. These findings indicate that three-dimensional finite element simulation is a feasible method for analyzing stress and displacement at the anas- tomosis after autologous nerve grafting.

Analysis of Three-dimensional Crack Propagation by Using Displacement Discontinuity Method

A technique for modelling of three-dimensional(3D)quasi-statically propagating cracks in elastic bodies by the displacement discontinuity method(DDM)was described.When the crack is closed,the Mohr-coulomb rule on the two contacted surfaces of the crack must be satisfied.A simple iterative method was adopted in order to consider three different states of cracks.Under the assumption that the advance of the point on the crack front would occur only in the normal plane which is through this edge point,the maximum energy release rate criterion is modified to be used as the criterion for the crack growth.With discretization,the process of crack propagation can be seen as the advance of the vertices of the crack front.The program MCP3D was developed based on these theories to simulate the 3D quasi-static crack propagation.A numerical example of a penny-shaped crack subject to tension and compression in an infinite elastic media was analyzed with MCP3D,and the results in comparison with others' show that the present method for 3D crack propagation is effective.

Measurement of absolute three-dimensional displacement gradients using tri-color quad-beam digital shearography

A tri-color quad-beam digital shearography is proposed to achieve the measurement of absolute three-dimensional(3D) displacement gradients.Four laser beams with three different center wavelengths are symmetrically irradiated to the object surface from the upper and lower left and right directions.Four phase maps are then extracted from the two interferograms obtained from two shots.Based on these four phase maps,the absolute 3D displacement gradients are determined.This means of absolute 3D displacement gradient measurement effectively improves the measurement capability of digital shearography and expands its application range.

Double Beams to Measure Three-dimensional Rigid Body Displacements

A new method for measuring 3-D rigid body displacements is proposed,in which two perpendicular beams are emitted onto two sensitive planes of PSDs being perpendicular to each other.The method can be used to measure 1-D or 2-D displacements when required.Moreover,the experimental results are presented,which demonstrate that the new method has high accuracy,fast processing speed,high reliability,and easily being realized.

A theory for three-dimensional response of micropolar plates

Through combined applications of the transfer-matrix method and asymptotic expansion technique,we formulate a theory to predict the three-dimensional response of micropolar plates.No ad hoc assumptions regarding through-thickness assumptions of the field variables are made,and the governing equations are two-dimensional,with the displacements and microrotations of the mid-plane as the unknowns.Once the deformation of the mid-plane is solved,a three-dimensional micropolar elastic field within the plate is generated,which is exact up to the second order except in the boundary region close to the plate edge.As an illustrative example,the bending of a clamped infinitely long plate caused by a uniformly distributed transverse force is analyzed and discussed in detail.

Oxygen tension modulates cell function in an in vitro three-dimensional glioblastoma tumor model

Hypoxia is a typical feature of the tumor microenvironment,one of the most critical factors affecting cell behavior and tumor progression.However,the lack of tumor models able to precisely emulate natural brain tumor tissue has impeded the study of the effects of hypoxia on the progression and growth of tumor cells.This study reports a three-dimensional(3D)brain tumor model obtained by encapsulating U87MG(U87)cells in a hydrogel containing type I collagen.It also documents the effect of various oxygen concentrations(1%,7%,and 21%)in the culture environment on U87 cell morphology,proliferation,viability,cell cycle,apoptosis rate,and migration.Finally,it compares two-dimensional(2D)and 3D cultures.For comparison purposes,cells cultured in flat culture dishes were used as the control(2D model).Cells cultured in the 3D model proliferated more slowly but had a higher apoptosis rate and proportion of cells in the resting phase(G0 phase)/gap I phase(G1 phase)than those cultured in the 2D model.Besides,the two models yielded significantly different cell morphologies.Finally,hypoxia(e.g.,1%O2)affected cell morphology,slowed cell growth,reduced cell viability,and increased the apoptosis rate in the 3D model.These results indicate that the constructed 3D model is effective for investigating the effects of biological and chemical factors on cell morphology and function,and can be more representative of the tumor microenvironment than 2D culture systems.The developed 3D glioblastoma tumor model is equally applicable to other studies in pharmacology and pathology.

Three-dimensional cell-based strategies for liver regeneration

Liver regeneration and the development of effective therapies for liver failure remain formidable challenges in modern medicine.In recent years,the utilization of 3D cell-based strategies has emerged as a promising approach for addressing these urgent clinical requirements.This review provides a thorough analysis of the application of 3D cell-based approaches to liver regeneration and their potential impact on patients with end-stage liver failure.Here,we discuss various 3D culture models that incorporate hepatocytes and stem cells to restore liver function and ameliorate the consequences of liver failure.Furthermore,we explored the challenges in transitioning these innovative strategies from preclinical studies to clinical applications.The collective insights presented herein highlight the significance of 3D cell-based strategies as a transformative paradigm for liver regeneration and improved patient care.

Three-dimensional visualization technology for guiding one-step percutaneous transhepatic cholangioscopic lithotripsy for the treatment of complex hepatolithiasis

BACKGROUND Biliary stone disease is a highly prevalent condition and a leading cause of hospitalization worldwide.Hepatolithiasis with associated strictures has high residual and recurrence rates after traditional multisession percutaneous transhepatic cholangioscopic lithotripsy(PTCSL).AIM To study one-step PTCSL using the percutaneous transhepatic one-step biliary fistulation(PTOBF)technique guided by three-dimensional(3D)visualization.METHODS This was a retrospective,single-center study analyzing,140 patients who,between October 2016 and October 2023,underwent one-step PTCSL for hepatolithiasis.The patients were divided into two groups:The 3D-PTOBF group and the PTOBF group.Stone clearance on choledochoscopy,complications,and long-term clearance and recurrence rates were assessed.RESULTS Age,total bilirubin,direct bilirubin,Child-Pugh class,and stone location were similar between the 2 groups,but there was a significant difference in bile duct strictures,with biliary strictures more common in the 3D-PTOBF group(P=0.001).The median follow-up time was 55.0(55.0,512.0)days.The immediate stone clearance ratio(88.6%vs 27.1%,P=0.000)and stricture resolution ratio(97.1%vs 78.6%,P=0.001)in the 3D-PTOBF group were significantly greater than those in the PTOBF group.Postoperative complication(8.6%vs 41.4%,P=0.000)and stone recurrence rates(7.1%vs 38.6%,P=0.000)were significantly lower in the 3D-PTOBF group.CONCLUSION Three-dimensional visualization helps make one-step PTCSL a safe,effective,and promising treatment for patients with complicated primary hepatolithiasis.The perioperative and long-term outcomes are satisfactory for patients with complicated primary hepatolithiasis.This minimally invasive method has the potential to be used as a substitute for hepatobiliary surgery.

The combined application of stem cells and three-dimensional bioprinting scaffolds for the repair of spinal cord injury

Spinal cord injury is considered one of the most difficult injuries to repair and has one of the worst prognoses for injuries to the nervous system.Following surgery,the poor regenerative capacity of nerve cells and the generation of new scars can make it very difficult for the impaired nervous system to restore its neural functionality.Traditional treatments can only alleviate secondary injuries but cannot fundamentally repair the spinal cord.Consequently,there is a critical need to develop new treatments to promote functional repair after spinal cord injury.Over recent years,there have been seve ral developments in the use of stem cell therapy for the treatment of spinal cord injury.Alongside significant developments in the field of tissue engineering,three-dimensional bioprinting technology has become a hot research topic due to its ability to accurately print complex structures.This led to the loading of three-dimensional bioprinting scaffolds which provided precise cell localization.These three-dimensional bioprinting scaffolds co uld repair damaged neural circuits and had the potential to repair the damaged spinal cord.In this review,we discuss the mechanisms underlying simple stem cell therapy,the application of different types of stem cells for the treatment of spinal cord injury,and the different manufa cturing methods for three-dimensional bioprinting scaffolds.In particular,we focus on the development of three-dimensional bioprinting scaffolds for the treatment of spinal cord injury.

Comparison of displacement damage effects on the dark signal in CMOS image sensors induced by CSNS back-n and XAPR neutrons

This study investigates the effects of displacement damage on the dark signal of a pinned photodiode CMOS image sensor(CIS)following irradiation with back-streaming white neutrons from white neutron sources at the China spallation neutron source(CSNS)and Xi'an pulsed reactor(XAPR).The mean dark signal,dark signal non-uniformity(DSNU),dark signal distribution,and hot pixels of the CIS were compared between the CSNS back-n and XAPR neutron irradiations.The nonionizing energy loss and energy distribution of primary knock-on atoms in silicon,induced by neutrons,were calculated using the open-source package Geant4.An analysis combining experimental and simulation results showed a noticeable proportionality between the increase in the mean dark signal and the displacement damage dose(DDD).Additionally,neutron energies influence DSNU,dark signal distribution,and hot pixels.High neutron energies at the same DDD level may lead to pronounced dark signal non-uniformity and elevated hot pixel values.

Data-augmented landslide displacement prediction using generative adversarial network

Landslides are destructive natural disasters that cause catastrophic damage and loss of life worldwide.Accurately predicting landslide displacement enables effective early warning and risk management.However,the limited availability of on-site measurement data has been a substantial obstacle in developing data-driven models,such as state-of-the-art machine learning(ML)models.To address these challenges,this study proposes a data augmentation framework that uses generative adversarial networks(GANs),a recent advance in generative artificial intelligence(AI),to improve the accuracy of landslide displacement prediction.The framework provides effective data augmentation to enhance limited datasets.A recurrent GAN model,RGAN-LS,is proposed,specifically designed to generate realistic synthetic multivariate time series that mimics the characteristics of real landslide on-site measurement data.A customized moment-matching loss is incorporated in addition to the adversarial loss in GAN during the training of RGAN-LS to capture the temporal dynamics and correlations in real time series data.Then,the synthetic data generated by RGAN-LS is used to enhance the training of long short-term memory(LSTM)networks and particle swarm optimization-support vector machine(PSO-SVM)models for landslide displacement prediction tasks.Results on two landslides in the Three Gorges Reservoir(TGR)region show a significant improvement in LSTM model prediction performance when trained on augmented data.For instance,in the case of the Baishuihe landslide,the average root mean square error(RMSE)increases by 16.11%,and the mean absolute error(MAE)by 17.59%.More importantly,the model’s responsiveness during mutational stages is enhanced for early warning purposes.However,the results have shown that the static PSO-SVM model only sees marginal gains compared to recurrent models such as LSTM.Further analysis indicates that an optimal synthetic-to-real data ratio(50%on the illustration cases)maximizes the improvements.This also demonstrates the robustness and effectiveness of supplementing training data for dynamic models to obtain better results.By using the powerful generative AI approach,RGAN-LS can generate high-fidelity synthetic landslide data.This is critical for improving the performance of advanced ML models in predicting landslide displacement,particularly when there are limited training data.Additionally,this approach has the potential to expand the use of generative AI in geohazard risk management and other research areas.

Virtual and augmented reality systems and three-dimensional printing of the renal model—novel trends to guide preoperative planning for renal cancer

ObjectiveThis study aimed to explore the applications of three-dimensional (3D) technology, including virtual reality, augmented reality (AR), and 3D printing system, in the field of medicine, particularly in renal interventions for cancer treatment.MethodsA specialized software transforms 2D medical images into precise 3D digital models, facilitating improved anatomical understanding and surgical planning. Patient-specific 3D printed anatomical models are utilized for preoperative planning, intraoperative guidance, and surgical education. AR technology enables the overlay of digital perceptions onto real-world surgical environments.ResultsPatient-specific 3D printed anatomical models have multiple applications, such as preoperative planning, intraoperative guidance, trainee education, and patient counseling. Virtual reality involves substituting the real world with a computer-generated 3D environment, while AR overlays digitally created perceptions onto the existing reality. The advances in 3D modeling technology have sparked considerable interest in their application to partial nephrectomy in the realm of renal cancer. 3D printing, also known as additive manufacturing, constructs 3D objects based on computer-aided design or digital 3D models. Utilizing 3D-printed preoperative renal models provides benefits for surgical planning, offering a more reliable assessment of the tumor's relationship with vital anatomical structures and enabling better preparation for procedures. AR technology allows surgeons to visualize patient-specific renal anatomical structures and their spatial relationships with surrounding organs by projecting CT/MRI images onto a live laparoscopic video. Incorporating patient-specific 3D digital models into healthcare enhances best practice, resulting in improved patient care, increased patient satisfaction, and cost saving for the healthcare system.

High-speed autopolarization synchronization modulation three-dimensional structured illumination microscopy

In recent years,notable progress has been achieved in both the hardware and algorithms of structured illumination microscopy(SIM).Nevertheless,the advancement of three-dimensional structured illumination microscopy(3DSIM)has been impeded by challenges arising from the speed and intricacy of polarization modulation.We introduce a high-speed modulation 3DSIM system,leveraging the polarizationmaintaining and modulation capabilities of a digital micromirror device(DMD)in conjunction with an electrooptic modulator.The DMD-3DSIM system yields a twofold enhancement in both lateral(133 nm)and axial(300 nm)resolution compared to wide-field imaging and can acquire a data set comprising 29 sections of 1024 pixels×1024 pixels,with 15 ms exposure time and 6.75 s per volume.The versatility of the DMD-3DSIM approach was exemplified through the imaging of various specimens,including fluorescent beads,nuclear pores,microtubules,actin filaments,and mitochondria within cells,as well as plant and animal tissues.Notably,polarized 3DSIM elucidated the orientation of actin filaments.Furthermore,the implementation of diverse deconvolution algorithms further enhances 3D resolution.The DMD-based 3DSIM system presents a rapid and reliable methodology for investigating biomedical phenomena,boasting capabilities encompassing 3D superresolution,fast temporal resolution,and polarization imaging.

Simulation of Rotating Asymmetric Sideways Forces during Vertical Displacement Events in CFETR

Tokamak plasmas with elongated cross sections are susceptible to vertical displacement events(VDEs),which can damage the first wall via heat flux or electromagnetic(EM)forces.We present a 3D nonlinear reduced magnetohydrodynamic(MHD)simulation of CFETR plasma during a cold VDE following the thermal quench,focusing on the relationship among the EM force,plasma displacement,and the n=1 mode.The dominant mode,identified as m/n=2/1,becomes destabilized when most of the current is contracted within the q=2 surface.The displacement of the plasma current centroid is less than that of the magnetic axis due to the presence of SOL current in the open field line region.Hence,the symmetric component of the induced vacuum vessel current is significantly mitigated.The direction of the sideways force keeps a constant phase approximately compared to the asymmetric component of the vacuum vessel current and the SOL current,which in turn keep in-phase with the dominant 2/1 mode.Their amplitudes are also closely associated with the growth of the dominant mode.These findings provide insights into potential methods for controlling the phase and amplitude of sideways forces during VDEs in the future.

Effects of Fluorescent Pair on the Kinetics of DNA Strand Displacement Reaction

Fluorescent labels are widely used in the characterizations of DNA-based reaction network operations.We systematically studied the effects of commonly used fluorescent pairs on thermal stabilities of signal-substrate duplex and the strand displacement kinetics.It is demonstrated that the modifications of duplex with fluorescent pairs stabilize DNA duplex by up to 3.5°C,and the kinetics of DNA strand displacement circuit is also evidently slowed down.These results highlight the importance of fluorescent pairs towards the kinetic modulation in designing nucleic acid probes and complex DNA dynamic circuits.

Development of a toroidal soft x-ray imaging system and application for investigating three-dimensional plasma on J-TEXT

A toroidal soft x-ray imaging(T-SXRI)system has been developed to investigate threedimensional(3D)plasma physics on J-TEXT.This T-SXRI system consists of three sets of SXR arrays.Two sets are newly developed and located on the vacuum chamber wall at toroidal positionsφof 126.4°and 272.6°,respectively,while one set was established previously atφ=65.50.Each set of SXR arrays consists of three arrays viewing the plasma poloidally,and hence can be used separately to obtain SXR images via the tomographic method.The sawtooth precursor oscillations are measured by T-SXRI,and the corresponding images of perturbative SXR signals are successfully reconstructed at these three toroidal positions,hence providing measurement of the 3D structure of precursor oscillations.The observed 3D structure is consistent with the helical structure of the m/n=1/1 mode.The experimental observation confirms that the T-SXRI system is able to observe 3D structures in the J-TEXT plasma.

Intraoperative application of three-dimensional printed guides in total hip arthroplasty: A systematic review

BACKGROUND Acetabular component positioning in total hip arthroplasty(THA)is of key importance to ensure satisfactory post-operative outcomes and to minimize the risk of complications.The majority of acetabular components are aligned freehand,without the use of navigation methods.Patient specific instruments(PSI)and three-dimensional(3D)printing of THA placement guides are increasingly used in primary THA to ensure optimal positioning.AIM To summarize the literature on 3D printing in THA and how they improve acetabular component alignment.METHODS PubMed was used to identify and access scientific studies reporting on different 3D printing methods used in THA.Eight studies with 236 hips in 228 patients were included.The studies could be divided into two main categories;3D printed models and 3D printed guides.RESULTS 3D printing in THA helped improve preoperative cup size planning and post-operative Harris hip scores between intervention and control groups(P=0.019,P=0.009).Otherwise,outcome measures were heterogeneous and thus difficult to compare.The overarching consensus between the studies is that the use of 3D guidance tools can assist in improving THA cup positioning and reduce the need for revision THA and the associated costs.CONCLUSION The implementation of 3D printing and PSI for primary THA can significantly improve the positioning accuracy of the acetabular cup component and reduce the number of complications caused by malpositioning.