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Prediction of three-dimensional ocean temperature in the South China Sea based on time series gridded data and a dynamic spatiotemporal graph neural network
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作者 Feng Nan Zhuolin Li +3 位作者 Jie Yu Suixiang Shi Xinrong Wu Lingyu Xu 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2024年第7期26-39,共14页
Ocean temperature is an important physical variable in marine ecosystems,and ocean temperature prediction is an important research objective in ocean-related fields.Currently,one of the commonly used methods for ocean... Ocean temperature is an important physical variable in marine ecosystems,and ocean temperature prediction is an important research objective in ocean-related fields.Currently,one of the commonly used methods for ocean temperature prediction is based on data-driven,but research on this method is mostly limited to the sea surface,with few studies on the prediction of internal ocean temperature.Existing graph neural network-based methods usually use predefined graphs or learned static graphs,which cannot capture the dynamic associations among data.In this study,we propose a novel dynamic spatiotemporal graph neural network(DSTGN)to predict threedimensional ocean temperature(3D-OT),which combines static graph learning and dynamic graph learning to automatically mine two unknown dependencies between sequences based on the original 3D-OT data without prior knowledge.Temporal and spatial dependencies in the time series were then captured using temporal and graph convolutions.We also integrated dynamic graph learning,static graph learning,graph convolution,and temporal convolution into an end-to-end framework for 3D-OT prediction using time-series grid data.In this study,we conducted prediction experiments using high-resolution 3D-OT from the Copernicus global ocean physical reanalysis,with data covering the vertical variation of temperature from the sea surface to 1000 m below the sea surface.We compared five mainstream models that are commonly used for ocean temperature prediction,and the results showed that the method achieved the best prediction results at all prediction scales. 展开更多
关键词 dynamic associations three-dimensional ocean temperature prediction graph neural network time series gridded data
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Three-dimensional dynamics of supported pipes conveying fluid 被引量:9
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作者 L.Wang T.L.Jiang H.L.Dai 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2017年第6期1065-1074,共10页
This paper deals with the three-dimensional dynamics and postbuckling behavior of flexible supported pipes conveying fluid, considering flow velocities lower and higher than the critical value at which the buckling in... This paper deals with the three-dimensional dynamics and postbuckling behavior of flexible supported pipes conveying fluid, considering flow velocities lower and higher than the critical value at which the buckling instability occurs. In the case of low flow velocity, the pipe is stable with a straight equilibrium position and the dynamics of the system can be examined using linear theory. When the flow velocity is beyond the critical value, any motions of the pipe could be around the postbuckling configuration(non-zero equilibrium position) rather than the straight equilibrium position, so nonlinear theory is required. The nonlinear equations of perturbed motions around the postbuckling configuration are derived and solved with the aid of Galerkin discretization. It is found, for a given flow velocity,that the first-mode frequency for in-plane motions is quite different from that for out-of-plane motions. However, the second-or third-mode frequencies for in-plane motions are approximately equal to their counterparts for out-of-plane motions, keeping almost constant values with increasing flow velocity. Moreover, the orientation angle of the postbuckling configuration plane for a buckled pipe can be significantly affected by initial conditions, displaying new features which have not been observed in the same pipe system factitiously supposed to deform in a single plane. 展开更多
关键词 Pipe conveying fluid three-dimensional dynamics INSTABILITY Natural frequency Postbuckling configuration
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Three-dimensional Computational Fluid Dynamics Modeling of Two-phase Flow in a Structured Packing Column 被引量:4
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作者 张小斌 姚蕾 +1 位作者 邱利民 张学军 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2013年第9期959-966,共8页
Characterizing the complex two-phase hydrodynamics in structured packed columns requires a power- ful modeling tool. The traditional two-dimensional model exhibits limitations when one attempts to model the de- tailed... Characterizing the complex two-phase hydrodynamics in structured packed columns requires a power- ful modeling tool. The traditional two-dimensional model exhibits limitations when one attempts to model the de- tailed two-phase flow inside the columns. The present paper presents a three-dimensional computational fluid dy- namics (CFD) model to simulate the two-phase flow in a representative unit of the column. The unit consists of an CFD calculations on column packed with Flexipak 1Y were implemented within the volume of fluid (VOF) mathe- matical framework. The CFD model was validated by comparing the calculated thickness of liquid film with the available experimental data. Special attention was given to quantitative analysis of the effects of gravity on the hy- drodynamics. Fluctuations in the liquid mass flow rate and the calculated pressure drop loss were found to be quali- tatively in agreement with the experimental observations. 展开更多
关键词 structured packing column two-phase flow computational fluid dynamics three-dimension
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Predicting the Dynamic Behavior of Asphalt Concrete Using Three-dimensional Discrete Element Method 被引量:4
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作者 陈俊 PAN Tongyan +2 位作者 CHEN Jingya HUANG Xiaoming LU Yang 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2012年第2期382-388,共7页
A user-defined three-dimensional (3D) discrete element model was presented to predict the dynamic modulus and phase angle of asphalt concrete (AC). The 3D discrete element method (DEM) model of AC was constructe... A user-defined three-dimensional (3D) discrete element model was presented to predict the dynamic modulus and phase angle of asphalt concrete (AC). The 3D discrete element method (DEM) model of AC was constructed employing a user-defined computer program developed using the "Fish" language in PFC3D. Important microstructural features of AC were modeled, including aggregate gradation, air voids and mastic. The irregular shape of aggregate particle was modeled using a clump of spheres. The developed model was validated through comparing with experimental measurements and then used to simulate the cyclic uniaxial compression test, based on which the dynamic modulus and phase angle were calculated from the output stress- strain relationship. The effects of air void content, aggregate stiffness and volumetric fraction on AC modulus were further investigated. The experimental results show that the 3D DEM model is able to accurately predict both dynamic modulus and phase angle of AC across a range of temperature and loading frequencies. The user- defined 3D model also demonstrated significant improvement over the general existing two-dimensional models. 展开更多
关键词 asphalt concrete dynamic modulus MICROMECHANICS discrete element method three-dimensional model uniaxial compression test
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Science Letters:Dynamic concision for three-dimensional reconstruction of human organ built with virtual reality modelling language (VRML) 被引量:3
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作者 禹正杨 郑树森 +2 位作者 陈雷霆 何晓乾 王建军 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2005年第7期611-616,共6页
This research studies the process of 3D reconstruction and dynamic concision based on 2D medical digital images using virtual reality modelling language (VRML) and JavaScript language, with a focus on how to realize t... This research studies the process of 3D reconstruction and dynamic concision based on 2D medical digital images using virtual reality modelling language (VRML) and JavaScript language, with a focus on how to realize the dynamic concision of 3D medical model with script node and sensor node in VRML. The 3D reconstruction and concision of body internal organs can be built with such high quality that they are better than those obtained from the traditional methods. With the function of dynamic concision, the VRML browser can offer better windows for man-computer interaction in real-time environment than ever before. 3D reconstruction and dynamic concision with VRML can be used to meet the requirement for the medical observation of 3D reconstruction and have a promising prospect in the fields of medical imaging. 展开更多
关键词 Virtual Reality Modelling Language (VRML) Direct texture mapping three-dimensional reconstruction dynamic concision
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Three-dimensional coordinates test method with uncertain projectile proximity explosion position based on dynamic seven photoelectric detection screen 被引量:2
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作者 Han-shan Li Xiao-qian Zhang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2022年第9期1643-1652,共10页
To objectively obtain the three-dimensional coordinates of the projectile fuze proximity explosion when projectile intersects the head of missile target, we propose a dynamic seven photoelectric detection screen test ... To objectively obtain the three-dimensional coordinates of the projectile fuze proximity explosion when projectile intersects the head of missile target, we propose a dynamic seven photoelectric detection screen test method, which is made up of six plane detection screens and a flash photoelectric dynamic detection screen. The three-dimensional coordinates calculation model of the projectile proximity explosion position based on seven plane detection screens with dynamic characteristics is established.According to the relation of the dynamic seven photoelectric detection screen planes and the time values,the analytical function of the projectile proximity explosion position parameters under non-linear motion is derived. The projectile signal filtering method based on discrete wavelet transform is explored in this work. Additionally, the projectile signal recognition algorithm using an improved particle swarm is proposed. Based on the characteristics of the time duration and the signal peak error for the projectile passing through the detection screen, the signals attribution of the same projectile passing through six detection screens are analyzed for obtaining precise time values of the same projectile passing through the detection screens. On the basis of the projectile fuze proximity explosion test, the linear motion model and the proposed non-linear motion model are used to calculate and compare the same group of projectiles proximity explosion position parameters. The comparison of test results verifies that the proposed test method and calculation model in this work accurately obtain the actual projectile proximity explosion position parameters. 展开更多
关键词 dynamic multi-screen array plane Flash photoelectric detection target Projectile signal processing Particle swarm Proximity explosion fuze three-dimensional coordinate
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CONVOLUTION OF THE IMPACT THREE-DIMENSIONAL ELASTO-DYNAMICS AND DYNAMIC STRESS INTENSITY FACTOR FOR AN ELLIPTIC CRACK
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作者 孙竹凤 范天佑 吴祥法 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2002年第3期302-308,共7页
This paper presents a formulation for three-dimensional elasto-dynamics with an elliptic crack based on the Laplace and Fourier transforms and the convolution theorem. The dynamic stress intensity factor for the crack... This paper presents a formulation for three-dimensional elasto-dynamics with an elliptic crack based on the Laplace and Fourier transforms and the convolution theorem. The dynamic stress intensity factor for the crack is determined by solving a Fredholm integral equation of the first kind. The results of this paper are very close to those given by the two-dimensional dual integral equation method. 展开更多
关键词 dynamic loading three-dimensional elliptic crack dynamic stress intensity factor
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Three-Dimensional Nonlinear Dynamic Model and Macro Control of Real Estate
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作者 Dan Ma Shengwu Zhou Haojin Lv 《Intelligent Information Management》 2010年第5期325-328,共4页
In this paper, according to economics of real estate and macro-control theory, combine with the characteristics of the real estate market, macro-control of the real estate market is studied. After giving the dynamic m... In this paper, according to economics of real estate and macro-control theory, combine with the characteristics of the real estate market, macro-control of the real estate market is studied. After giving the dynamic model of three-dimensional nonlinear differential equations based on the total number of houses on the real estate business, the government’s averages housing investment funds and the standard price, systematically established the stability conditions of equilibrium point for this model. What’s more, through the use of extreme value analysis model, government funds have been invested in real estate business building devotion principles and the construction base of the real estate businessmen has also been estimated successfully. This provides the corresponding theoretical basis for government macro control policy-making. 展开更多
关键词 REAL ESTATE MACRO Control three-dimensional dynamic Model EXTREME Value Analysis
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In-situ three-dimensional visualization of dynamic tension deformation in ferrite stainless steels
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作者 ZHANG Zhixia BI Hongyun LI Xin 《Baosteel Technical Research》 CAS 2013年第4期56-61,共6页
An improved three-dimensional (3-D) experimental visualization methodology is presented tor evaluating the fracture mechanisms of ferritic stainless steels by in-situ tensile testing with an environmental scanning e... An improved three-dimensional (3-D) experimental visualization methodology is presented tor evaluating the fracture mechanisms of ferritic stainless steels by in-situ tensile testing with an environmental scanning electron microscope (ESEM). The samples were machined with a radial notched shape and a sloped surface. Both planar surface deformation and sloping surface deformation-induced microvoids were observed during dynamic tension experiments, where a greater amount of information could be obtained from the sloping surface. The results showed that microvoids formed at the grain boundaries of highly elongated large grains. The microvoids nucleated in the severely deformed regions grew nearly parallel to the tensile axis, predominantly along the grain boundaries. The microvoids nucleated at the interface of particles and the matrix did not propagate due to the high plasticity of the matrix. The large microvoids propagated and showed a zigzag shape along the grain boundaries,seemingly a consequence of the fracture of the slip bands caused by dislocation pile-ups. The final failure took place due to the reduction of the load-beating area. 展开更多
关键词 three-dimensional (3-D) visualization MICROVOIDS in-situ dynamic tensile testing ferritic stainless steels
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Impact of the synergy between technology management and technological capability on new product development:a system dynamics approach 被引量:2
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作者 MA Qian WU Weiwei +2 位作者 LIU Yexin LIANG Zhou KOU Lingzhi 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2022年第1期105-119,共15页
This paper employs system dynamics to explore how the synergy between technology management and technological capability affects new product development.The results show that the synergy between technology management ... This paper employs system dynamics to explore how the synergy between technology management and technological capability affects new product development.The results show that the synergy between technology management and technological capability has positive impact on new product development.Moreover, the leading synergy processes between technology management and technological capability in different new product development stages are different.This paper deepens the theoretical understanding of how to achieve new product development, and also provides useful guidance for firms to implement new product development. 展开更多
关键词 technology management technological capability new product development system dynamics
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Research on Quantitative Identification of Three-Dimensional Connectivity of Fractured-Vuggy Reservoirs
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作者 Xingliang Deng Peng Cao +3 位作者 Yintao Zhang Yuhui Zhou Xiao Luo Liang Wang 《Energy Engineering》 EI 2024年第5期1195-1207,共13页
The fractured-vuggy carbonate oil resources in the western basin of China are extremely rich.The connectivity of carbonate reservoirs is complex,and there is still a lack of clear understanding of the development and ... The fractured-vuggy carbonate oil resources in the western basin of China are extremely rich.The connectivity of carbonate reservoirs is complex,and there is still a lack of clear understanding of the development and topological structure of the pore space in fractured-vuggy reservoirs.Thus,effective prediction of fractured-vuggy reservoirs is difficult.In view of this,this work employs adaptive point cloud technology to reproduce the shape and capture the characteristics of a fractured-vuggy reservoir.To identify the complex connectivity among pores,fractures,and vugs,a simplified one-dimensional connectivity model is established by using the meshless connection element method(CEM).Considering that different types of connection units have different flow characteristics,a sequential coupling calculation method that can efficiently calculate reservoir pressure and saturation is developed.By automatic history matching,the dynamic production data is fitted in real-time,and the characteristic parameters of the connection unit are inverted.Simulation results show that the three-dimensional connectivity model of the fractured-vuggy reservoir built in this work is as close as 90%of the fine grid model,while the dynamic simulation efficiency is much higher with good accuracy. 展开更多
关键词 Fractured-vuggy reservoir three-dimensional connectivity connection unit dynamic prediction automatic history matching
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The Role of R&D Leverage as a Dynamic Capability in Performance Creation:Evidence from SMEs in Taiwan 被引量:2
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作者 Tung-Shan Liao 《Journal of Business Administration Research》 2019年第2期20-39,共20页
This study addresses the role of R&D leverage in SMEs’performance creation.The authors do so by considering SMEs’high resource dependence due to isomorphism.We propose that R&D leverage,with a presence of dy... This study addresses the role of R&D leverage in SMEs’performance creation.The authors do so by considering SMEs’high resource dependence due to isomorphism.We propose that R&D leverage,with a presence of dynamic capabilities,plays a moderating role in the relation between resource investments and performance.This study,which focused on Taiwan’s SMEs,conducts a questionnaire survey using the hierarchical sampling technique,across various industries and geographic areas in Taiwan.The empirical findings reveal that R&D leverage as an essential leveler in resource management enhances resource advantages. 展开更多
关键词 dynamic capabilities view R&D leverage ISOMORPHISM SMES FIRM PERFORMANCE DIVERGENCE
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Fluke 9640A RF Reference Source combines level precision,dynamic range,frequency capability in a single instrument
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作者 Stream lines workload enables automationof calibration procedures with MET/CAL(Plus Calibration Measurement Software 《国外电子测量技术》 2007年第1期81-81,共1页
关键词 Source RF Fluke 9640A RF Reference Source combines level precision dynamic range frequency capability in a single instrument
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Experimental and measured research on three-dimensional deformation law of gas drainage borehole in coal seam 被引量:8
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作者 Hongbao Zhao Jinyu Li +3 位作者 Yihong Liu Yikuo Wang Tao Wang Hui Cheng 《International Journal of Mining Science and Technology》 SCIE EI CSCD 2020年第3期397-403,共7页
Using self-researched gas drainage borehole stability dynamic monitoring device, three-dimensional deformation characteristics of borehole under steady vertical load were researched experimentally and systematically. ... Using self-researched gas drainage borehole stability dynamic monitoring device, three-dimensional deformation characteristics of borehole under steady vertical load were researched experimentally and systematically. This research indicated that under the action of steady loading, the mechanical deformation path of the simulated gas drainage borehole is gradually complicated, and the decay of the borehole circumferential strain is an important characterization of the prediction and early warning of borehole instability and collapse. The horizontal position of borehole occurs compressive strain, and the vertical of which occurs tensile strain under the action of vertical stress. At the initial stage of loading, the vertical strain is more sensitive than that in the horizontal direction. After a certain period of time, the horizontal strain is gradually higher than the vertical one, and the intersection of the borehole horizontal diameter and the hole wall is the stress concentration point. With the increase of the depth of hole, the strain shows a gradual decay trend as a whole, and the vertical strain decays more observably, but there is no absolute position correlation between the amount of strain decay and the increase in borehole depth,and the area within 1.5 times the orifice size is the borehole stress concentration zone. 展开更多
关键词 Gas drainage borehole dynamic monitoring Strain-time curve three-dimensional deformation law
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THE APPLICATION OF DISCRETE ELEMENT METHOD IN SOLVING THREE-DIMENTIONAL IMPACT DYNAMICS PROBLEMS 被引量:7
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作者 Liu Kaixin Gao Lingtian (Department of Mechanics and Engineering Science,Peking University,Beijing 100871,China) 《Acta Mechanica Solida Sinica》 SCIE EI 2003年第3期256-261,共6页
A three-dimensional discrete element model of the connective type is presented. Moreover,a three-dimensional numerical analysis code,which can carry out the transitional pro- cess from connective model(for continuum)t... A three-dimensional discrete element model of the connective type is presented. Moreover,a three-dimensional numerical analysis code,which can carry out the transitional pro- cess from connective model(for continuum)to contact model(for non-continuum),is developed for simulating the mechanical process from continuum to non-continuum.The wave propagation process in a concrete block(as continuum)made of cement grout under impact loading is numer- ically simulated with this code.By comparing its numerical results with those by LS-DYNA,the calculation accuracy of the model and algorithm is proved.Furthermore,the failure process of the concrete block under quasi-static loading is demonstrated,showing the basic dynamic tran- sitional process from continuum to non-continuum.The results of calculation can be displayed by animation.The damage modes are similar to the experimental results.The two numerical examples above prove that our model and its code are powerful and efficient in simulating the dynamic failure problems accompanying the transition from continuum to non-continuum.It also shows that the discrete element method(DEM)will have broad prospects for development and application. 展开更多
关键词 discrete element method three-dimensional model IMPACT stress wave dynamic failure
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Damage Initiation and Propagation in Composites Subjected to Low-Velocity Impact:Experimental Results,3D Dynamic Damage Model,and FEM Simulations 被引量:3
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作者 JIA Wenbin WEN Weidong FANG Lei 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI CSCD 2019年第3期488-499,共12页
A three-dimensional dynamic damage model that fits both small and large damage sizes is developed to predict impact damage initiation and propagation for each lamina of T300-carbon/epoxy laminations.First,13 specimens... A three-dimensional dynamic damage model that fits both small and large damage sizes is developed to predict impact damage initiation and propagation for each lamina of T300-carbon/epoxy laminations.First,13 specimens of the same lamination sequence are subjected to three different impact energies(10 J,15 J,and 20 J).After the impact,the laminates are inspected by the naked eye to observe the damage in the outer layers,and subsequently X-rayed to detect the inner damage.Next,the stress analysis of laminates subjected to impact loading is presented,based on the Hertz contact law and virtual displacement principle.Based on the analysis results,a three-dimensional dynamic damage model is proposed,including the Hou failure criteria and Camanho stiffness degradation model,to predict the impact damage shape and area.The numerical predictions of the damage shape and area show a relatively reasonable agreement with the experiments.Finally,the impact damage initiation and propagation for each lamina are investigated using this damage model,and the results improve the understanding of the impact process. 展开更多
关键词 COMPOSITES IMPACT three-dimensional dynamic DAMAGE model IMPACT DAMAGE INITIATION and PROPAGATION
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Static and dynamic finite element analysis of 304 stainless steel rod and wire hot continuous rolling process 被引量:5
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作者 Siyu Yuan Liwen Zhang +4 位作者 Shulun Liao Mao Li Min Qi Yu Zhen Shuqi Guo 《Journal of University of Science and Technology Beijing》 CSCD 2008年第3期324-329,共6页
Three-dimensional finite element models were developed to analyze 304 stainless steel rod and wire hot continuous rolling process with the help of MSC.Marc software. The entire 30-pass deformation process and the actu... Three-dimensional finite element models were developed to analyze 304 stainless steel rod and wire hot continuous rolling process with the help of MSC.Marc software. The entire 30-pass deformation process and the actual parameters of production line were taken into account. Static and dynamic procedures were used to study the continuous rolling process with the aid of the thermo-mechanical coupled FEM of elastic-plasticity. The properties of billets, such as deformation, temperature field and rolling force, were mainly discussed. The simulation results of temperature agree well with the measured values. Comparisons of the analysis results obtained using static implicit method and dynamic implicit method were presented. It is shown that static implicit procedure is more accurate than dynamic implicit procedure and is able to simulate the rolling process with a lower speed, such as a roughing mill. Whereas, dynamic analysis shows a higher efficiency than static analysis and is fit for simulating the rolling process with a higher speed, such as a finishing mill. 展开更多
关键词 304 stainless steel static implicit dynamic implicit three-dimensional simulation continuous rolling
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THREE-DIMENSIONAL ELLIPTIC CRACK UNDER IMPACT LOADING 被引量:4
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作者 Sun Zhufeng Wu Xiangfa Fan Tianyou 《Acta Mechanica Solida Sinica》 SCIE EI 2001年第4期312-316,共5页
The dynamic stress intensity factor of a three-dimensionalelliptic crack under impact loading is determined with the finiteelement method. The computation results can take into account theinfluence of time and the rat... The dynamic stress intensity factor of a three-dimensionalelliptic crack under impact loading is determined with the finiteelement method. The computation results can take into account theinfluence of time and the ratio of the wave speeds on the stressintensity factor. The present method is suitable not only forthree-dimensional dynamic crack, but also for three-dimensionaldynamic contact. 展开更多
关键词 dynamic loading three-dimensional elliptic crack finite element dynamicstress intensity factor
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Computational fluid dynamics simulations of respiratory airflow in human nasal cavity and its characteristic dimension study 被引量:3
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作者 Jun Zhang Yingxi Liu +2 位作者 Xiuzhen Sun Shen Yu Chi Yu 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2008年第2期223-228,共6页
To study the airflow distribution in human nasal cavity during respiration and the characteristic parameters of nasal structure, three-dimensional, anatomically accurate representations of 30 adult nasal cavity models... To study the airflow distribution in human nasal cavity during respiration and the characteristic parameters of nasal structure, three-dimensional, anatomically accurate representations of 30 adult nasal cavity models were recons- tructed based on processed tomography images collected from normal people. The airflow fields in nasal cavities were simulated by fluid dynamics with finite element software ANSYS. The results showed that the difference of human nasal cavity structure led to different airflow distribution in the nasal cavities and variation of the main airstream passing through the common nasal meatus. The nasal resistance in the regions of nasal valve and nasal vestibule accounted for more than half of the overall resistance. The characteristic model of nasal cavity was extracted on the basis of characteristic points and dimensions deduced from the original models. It showed that either the geometric structure or the airflow field of the two kinds of models was similar. The characteristic dimensions were the characteristic parameters of nasal cavity that could properly represent the original model in model studies on nasal cavity. 展开更多
关键词 Nasal cavity Characteristic dimension three-dimensional reconstruction Numerical simulation of flowfield Computational fluid dynamic Finite element method
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Generation of dynamically perfused functional vascular network system within hydrogel using3D bio-printing technology 被引量:1
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作者 Vivian K.Lee Seung-Schik Yoo +1 位作者 Peter Vincent Guohao Dai 《医用生物力学》 EI CAS CSCD 北大核心 2013年第S1期9-11,共3页
Introduction:3D bio-printing technology<sup>[1-3]</sup>(Figure 1)capable of dispensing live cells,soluble factors,and phase-changing hydrogel in a desired pattern,has great potential in creating 3D tissu... Introduction:3D bio-printing technology<sup>[1-3]</sup>(Figure 1)capable of dispensing live cells,soluble factors,and phase-changing hydrogel in a desired pattern,has great potential in creating 3D tissue.However,maintaining the viability of a thick tissue structure during tissue growth and maturation is challenging due to lack of adequate vascular perfusion.In a simple tissue model with 展开更多
关键词 HYDROGEL PRINTING PERFUSION dynamically challenging VIABILITY maintaining DESIRED thick capable
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