Effect of navigation endoscopy combined with threedimensional printing technology in the treatment of orbital blowout fractures

●AIM:To explore the combined application of surgical navigation nasal endoscopy(NNE)and three-dimensional printing technology(3DPT)for the adjunctive treatment of orbital blowout fractures(OBF).●METHODS:Retrospective analysis was conducted on the data of patients with OBF who underwent surgical treatment at the Affiliated Eye Hospital of Nanchang University between July 2012 and November 2022.The control group consisted of patients who received traditional surgical treatment(n=43),while the new surgical group(n=52)consisted of patients who received NNE with 3DPT.The difference in therapeutic effects between the two groups was evaluated by comparing the duration of the operation,best corrected visual acuity(BCVA),enophthalmos difference,recovery rate of eye movement disorder,recovery rate of diplopia,and incidence of postoperative complications.●RESULTS:The study included 95 cases(95 eyes),with 63 men and 32 women.The patients’age ranged from 5 to 67y(35.21±15.75y).The new surgical group and the control group exhibited no statistically significant differences in the duration of the operation,BCVA and enophthalmos difference.The recovery rates of diplopia in the new surgical group were significantly higher than those in the control group at 1mo[OR=0.03,95%CI(0.01–0.15),P<0.0000]and 3mo[OR=0.11,95%CI(0.03–0.36),P<0.0000]postoperation.Additionally,the recovery rates of eye movement disorders at 1 and 3mo after surgery were OR=0.08,95%CI(0.03–0.24),P<0.0000;and OR=0.01,95%CI(0.00–0.18),P<0.0000.The incidence of postoperative complications was lower in the new surgical group compared to the control group[OR=4.86,95%CI(0.95–24.78),P<0.05].●CONCLUSION:The combination of NNE and 3DPT can shorten the recovery time of diplopia and eye movement disorder in patients with OBF.

Three-dimensional printing for preoperative rehearsal and intraoperative navigation during laparoscopic rectal cancer surgery with left colic artery preservation

BACKGROUND Prior studies have shown that preserving the left colic artery(LCA)during laparo-scopic radical resection for rectal cancer(RC)can reduce the occurrence of anasto-motic leakage(AL),without compromising oncological outcomes.However,anatomical variations in the branches of the inferior mesenteric artery(IMA)and LCA present significant surgical challenges.In this study,we present our novel three dimensional(3D)printed IMA model designed to facilitate preoperative rehearsal and intraoperative navigation to analyze its impact on surgical safety.AIM To investigate the effect of 3D IMA models on preserving the LCA during RC surgery.METHODS We retrospectively collected clinical dates from patients with RC who underwent laparoscopic radical resection from January 2022 to May 2024 at Fuyang People’s Hospital.Patients were divided into the 3D printing and control groups for sta-tistical analysis of perioperative characteristics.RESULTS The 3D printing observation group comprised of 72 patients,while the control group comprised 68 patients.The operation time(174.5±38.2 minutes vs 198.5±49.6 minutes,P=0.002),intraoperative blood loss(43.9±31.3 mL vs 58.2±30.8 mL,P=0.005),duration of hospitalization(13.1±3.1 days vs 15.9±5.6 days,P<0.001),postoperative recovery time(8.6±2.6 days vs 10.5±4.9 days,P=0.007),and the postoperative complication rate(P<0.05)were all significantly lower in the observation group.CONCLUSION Utilization of a 3D-printed IMA model in laparoscopic radical resection of RC can assist surgeons in understanding the LCA anatomy preoperatively,thereby reducing intraoperative bleeding and shortening operating time,demonstrating better clinical application potential.

Current trends in three-dimensional visualization and real-time navigation as well as robot-assisted technologies in hepatobiliary surgery

With the continuous development of digital medicine,minimally invasive precision and safety have become the primary development trends in hepatobiliary surgery.Due to the specificity and complexity of hepatobiliary surgery,traditional preoperative imaging techniques such as computed tomography and magnetic resonance imaging cannot meet the need for identification of fine anatomical regions.Imaging-based three-dimensional(3D)reconstruction,virtual simulation of surgery and 3D printing optimize the surgical plan through preoperative assessment,improving the controllability and safety of intraoperative operations,and in difficult-to-reach areas of the posterior and superior liver,assistive robots reproduce the surgeon’s natural movements with stable cameras,reducing natural vibrations.Electromagnetic navigation in abdominal surgery solves the problem of conventional surgery still relying on direct visual observation or preoperative image assessment.We summarize and compare these recent trends in digital medical solutions for the future development and refinement of digital medicine in hepatobiliary surgery.

Application of Digital Technology in Road and Bridge Design

With the development and progress of science and technology,road and bridge design has experienced rapid development,from the initial manual drawing design to the popularity of Computer-Aided Design(CAD),and then to today’s digital software design era.Early designers relied on hand-drawn paper design forms which was time-consuming and error-prone.Digital support for road and bridge design not only saves the design time but the design quality has also achieved a qualitative leap.This paper engages in the application of digital technology in road and bridge design,to provide technical reference for China’s road and bridge engineering design units,to promote the popularity of Civil3D and other advanced design software in the field of engineering design and development,ultimately contributing to the sustainable development of China’s road and bridge engineering.

Current and future role of three-dimensional modelling technology in rectal cancer surgery:A systematic review

BACKGROUND Three-dimensional(3D)modelling technology translates the patient-specific anatomical information derived from two-dimensional radiological images into virtual or physical 3D models,which more closely resemble the complex environment encountered during surgery.It has been successfully applied to surgical planning and navigation,as well as surgical training and patient education in several surgical specialties,but its uptake lags behind in colorectal surgery.Rectal cancer surgery poses specific challenges due to the complex anatomy of the pelvis,which is difficult to comprehend and visualise.AIM To review the current and emerging applications of the 3D models,both virtual and physical,in rectal cancer surgery。METHODS Medline/PubMed,Embase and Scopus databases were searched using the keywords“rectal surgery”,“colorectal surgery”,“three-dimensional”,“3D”,“modelling”,“3D printing”,“surgical planning”,“surgical navigation”,“surgical education”,“patient education”to identify the eligible full-text studies published in English between 2001 and 2020.Reference list from each article was manually reviewed to identify additional relevant papers.The conference abstracts,animal and cadaveric studies and studies describing 3D pelvimetry or radiotherapy planning were excluded.Data were extracted from the retrieved manuscripts and summarised in a descriptive way.The manuscript was prepared and revised in accordance with PRISMA 2009 checklist.RESULTS Sixteen studies,including 9 feasibility studies,were included in the systematic review.The studies were classified into four categories:feasibility of the use of 3D modelling technology in rectal cancer surgery,preoperative planning and intraoperative navigation,surgical education and surgical device design.Thirteen studies used virtual models,one 3D printed model and 2 both types of models.The construction of virtual and physical models depicting the normal pelvic anatomy and rectal cancer,was shown to be feasible.Within the clinical context,3D models were used to identify vascular anomalies,for surgical planning and navigation in lateral pelvic wall lymph node dissection and in management of recurrent rectal cancer.Both physical and virtual 3D models were found to be valuable in surgical education,with a preference for 3D printed models.The main limitations of the current technology identified in the studies were related to the restrictions of the segmentation process and the lack of 3D printing materials that could mimic the soft and deformable tissues.CONCLUSION 3D modelling technology has potential to be utilised in multiple aspects of rectal cancer surgery,however,it is still at the experimental stage of application in this setting.

Three-dimensional printing technology for patient-matched instrument in treatment of cubitus varus deformity:A case report

BACKGROUND Recently,medical three-dimensional printing technology(3DPT)has demonstrated potential benefits for the treatment of cubitus varus deformity(CVD)by improving accuracy of the osteotomy through the use of an osteotomy guide,with or without a patient-mated plate.Here,we present an interesting CVD case,involving a patient who was treated with corrective biplanar chevron osteotomy using an innovative customized osteotomy guide and a newly designed patient-matched monoblock crosslink plate created with 3DPT.CASE SUMMARY A 32-year-old female presented with a significant CVD from childhood injury.A computer simulation was processed using images from computerized tomography scans of both upper extremities.The biplanar chevron osteotomy was designed to create identical anatomy between the mirror image of the contralateral distal humerus and the osteotomized distal humerus.Next,the customized osteotomy guide and patient-matched monoblock crosslink plate were designed and printed.A simulation osteotomy was created for the real-sized bone model,and the operation was performed using the posterior paratricipital approach with k-wire positioning from the customized osteotomy guide as a predrilled hole for screw fixation to achieve immediate control of the reduction after osteotomy.Our method allowed for successful treatment of the CVD case,significantly improving the patient’s radiographic and clinical outcomes,with satisfactory result.CONCLUSION 3DPT-created patient-matched osteotomy guide and instrumentation provides accurate control during CVD correction.

Navigation technology/eye-tracking in ophthalmology:principles,applications and benefits-a narrative review

Navigation technology in ophthalmology,colloquially called“eye-tracking”,has been applied to various areas of eye care.This approach encompasses motion-based navigation technology in both ophthalmic imaging and treatment.For instance,modern imaging instruments use a real-time eye-tracking system,which helps to reduce motion artefacts and increase signal-to-noise ratio in imaging acquisition such as optical coherence tomography(OCT),microperimetry,and fluorescence and color imaging.Navigation in ophthalmic surgery has been firstly applied in laser vision corrective surgery and spread to involve navigated retinal photocoagulation,and positioning guidance of intraocular lenses(IOL)during cataract surgery.It has emerged as one of the most reliable representatives of technology as it continues to transform surgical interventions into safer,more standardized,and more predictable procedures with better outcomes.Eye-tracking is essential in refractive surgery with excimer laser ablation.Using this technology for cataract surgery in patients with high preoperative astigmatism has produced better therapeutic outcomes.Navigated retinal laser has proven to be safer and more accurate compared to the use of conventional slit lamp lasers.Eye-tracking has also been used in imaging diagnostics,where it is essential for proper alignment of captured zones of interest and accurate follow-up imaging.This technology is not routinely discussed in the ophthalmic literature even though it has been truly impactful in our clinical practice and represents a small revolution in ophthalmology.

Speech Recognition Technology Applied to Intelligent Mobile Navigation System

The capability of human_computer interaction reflects the intelligent degree of mobile navigation system.The navigation data and functions of mobile navigation system are divided into system commands and non_system commands in this paper.And then a group of speech commands are abstracted.This paper applies speech recognition technology to intelligent mobile navigation system to process speech commands and does some deep research on the integration of speech recognition technology with mobile navigation system.The navigation operation can be performed by speech commands,which makes human_computer interaction easy during navigation.Speech command interface of navigation system is implemented by Dutty ++ Software,which is based on speech recognition system _Via Voice of IBM.Through navigation experiments,navigation can be done almost without keyboard,which proved that human_computer interaction is very convenient by speech commands and the reliability is also higher.

Application and Analysis of Computer Virtual Simulation Technology in Three-dimensional Animation Production

With the continuous promotion of computer technology, the application system of virtual simulation technology has been further optimized and improved, and has been widely used in various fields of social development, such as urban construction, interior design, industrial simulation and tourism teaching. China's three-dimensional animation production started relatively late, but has achieved good results with the support of related advanced technology in the process of development. Computer virtual simulation technology is an important technical support in the production of three-dimensional animation. In this paper, firstly, the related content of computer virtual simulation technology was introduced. Then, the specific application of this technology in the production of three-dimensional animation was further elaborated, so as to provide some reference for the improvement of the production effect of three-dimensional animation in the future.

Application Status and Prospect of Three-Dimensional Printing Technology in the Field of Medical Devices

Three-dimensional(3D)printing technology belongs to a new manufacturing science and has been widely used in various fields of industry.This article will apply 3D printing technology as its main research topic,with emphasis on its application in the field of medical devices and prospects for contribution.

Application of Three-dimensional Laser Scanning Technology in the Teaching Practice of Surveying and Mapping of Ancient Buildings

Based on the study of the application of three-dimensional laser scanning technology in ancient building surveying and mapping,this paper briefly describes the working principle and flow of three-dimensional laser scanning technology.Based on the practical application,this paper puts forward the discussion of related problems and matters needing attention.This has a certain reference significance for the study of new technology in surveying and mapping of ancient buildings.

Digital measurement of bone tumor volume by CT three-dimensional reconstruction technology

Objective To discuss the measurement of bone tumor volume on the basis of three dimensional images segmentation technology. Methods Twenty patients with lacunar bone tumor from Tianjin Hospital and Tongji Hospital were included in the

Local Scenario Perception and Web AR Navigation

This paper proposes a local point cloud map-based Web augmented reality(AR)indoor navigation system solution.By delivering the local point cloud map to the web front end for positioning,the real-time positioning can be implemented only with the help of the computing power of the web front end.In addition,with the characteristics of short time consumption and accurate positioning,an optimization solution to the local point cloud map is proposed,which includes specific measures such as descriptor de-duplicating and outlier removal,thus improving the quality of the point cloud.In this document,interpolation and smoothing effects are introduced for local map positioning,enhancing the anchoring effect and improving the smoothness and appearance of user experience.In small-scale indoor scenarios,the positioning frequency on an iPhone 13 can reach 30 fps,and the positioning precision is within 50 cm.Compared with an existing mainstream visual-based positioning manner for AR navigation,this specification does not rely on any additional sensor or cloud computing device,thereby greatly saving computing resources.It takes a very short time to meet the real-time requirements and provide users with a smooth positioning effect.

E-navigation发展与研究

阐述基于"大数据"理念、"互联网+"思维,及以"云技术"为支撑的由信息化技术、电子导航技术、E时代海事行业规范/标准、E-海事营运模式构架的新一代E-navigation技术及实现研究。

Research on CT characteristics reconstruction technology

The traditional computed tomography(CT)reconstruction methods are noisy,low resolution,poor contrast,and generally not suitable to detect the smaller flaws.Besides,the filter design is also difficult.The CT characteristics reconstruction technology was brought forward to improve in these aspects,which is defined to directly reconstruct the characteristics of the projection for the best requirements not the overall image quality.The two-dimension(2D)and three-dimension(3D)CT characteristics reconstruction algorithm were firstly introduced,then by detailed analysis,experimental results and comparsion of parameters calculated,its advantages in keeping better high-frequency feature,better noise immunity,short time-consuming and easier design are verified.

A tightly coupled rotational SINS/CNS integrated navigation method for aircraft

Strapdown inertial navigation system(SINS)/celestial navigation system(CNS)integrated navigation is widely used to achieve long-time and high-precision autonomous navigation for aircraft.In general,SINS/CNS integrated navigation can be divided into two integrated modes:loosely coupled integrated navigation and tightly coupled integrated navigation.Because the loosely coupled SINS/CNS integrated system is only available in the condition of at least three stars,the latter one is becoming a research hotspot.One major challenge of SINS/CNS integrated navigation is obtaining a high-precision horizon reference.To solve this problem,an innovative tightly coupled rotational SINS/CNS integrated navigation method is proposed.In this method,the rotational SINS error equation in the navigation frame is used as the state model,and the starlight vector and star altitude are used as measurements.Semi-physical simulations are conducted to test the performance of this integrated method.Results show that this tightly coupled rotational SINS/CNS method has the best navigation accuracy compared with SINS,rotational SINS,and traditional tightly coupled SINS/CNS integrated navigation method.

UPF based autonomous navigation scheme for deep space probe

The autonomous "celestial navigation scheme" for deep space probe departing from the earth and the autonomous "optical navigation scheme" for encountering object celestial body are presented. Then, aiming at the conditions that large initial estimation errors and non-Gaussian distribution of state or measurement errors may exist in orbit determination process of the two phases, UPF (unscented particle filter) is introduced into the navigation schemes. By tackling nonlinear and non-Gaussian problems, UPF overcomes the accuracy influence brought by the traditional EKF (extended Kalman filter), UKF (unscented Kalman filter), and PF (particle filter) schemes in approximate treatment to nonlinear and non-Gaussian state model and measurement model. The numerical simulations demonstrate the feasibility and higher accuracy of the UPF navigation scheme.

Multiconstraint adaptive three-dimensional guidance law using convex optimization

The traditional guidance law only guarantees the accuracy of attacking a target. However, the look angle and acceleration constraints are indispensable in applications. A new adaptive three-dimensional proportional navigation(PN) guidance law is proposed based on convex optimization. Decomposition of the three-dimensional space is carried out to establish threedimensional kinematic engagements. The constraints and the performance index are disposed by using the convex optimization method. PN guidance gains can be obtained by solving the optimization problem. This solution is more rapid and programmatic than the traditional method and provides a foundation for future online guidance methods, which is of great value for engineering applications.

Microfluidic three-dimensional cell culture of stem cells for high-throughput analysis

Although the recent advances in stem cell engineering have gained a great deal of attention due to their high potential in clinical research,the applicability of stem cells for preclinical screening in the drug discovery process is still challenging due to difficulties in controlling the stem cell microenvironment and the limited availability of high-throughput systems.Recently,researchers have been actively developing and evaluating three-dimensional(3D)cell culture-based platforms using microfluidic technologies,such as organ-on-a-chip and organoid-on-a-chip platforms,and they have achieved promising breakthroughs in stem cell engineering.In this review,we start with a comprehensive discussion on the importance of microfluidic 3D cell culture techniques in stem cell research and their technical strategies in the field of drug discovery.In a subsequent section,we discuss microfluidic 3D cell culture techniques for high-throughput analysis for use in stem cell research.In addition,some potential and practical applications of organ-on-a-chip or organoid-on-a-chip platforms using stem cells as drug screening and disease models are highlighted.