Application of three-dimensional speckle tracking technique in measuring left ventricular myocardial function in patients with diabetes

BACKGROUND Diabetic cardiomyopathy is considered as a chronic complication of diabetes mellitus(DM).Therefore,early detection of left ventricular systolic function(LVSF)damage in DM is essential.AIM To explore the use of the three-dimensional speckle tracking technique(3D-STI)for measuring LVSF in DM patients via meta-analysis.METHODS The electronic databases were retrieved from the initial accessible time to 29 April 2023.The current study involved 9 studies,including 970 subjects.We carried out this meta-analysis to estimate myocardial function in DM compared with controls according to myocardial strain attained by 3D-STI.RESULTS Night articles including 970 subjects were included.No significant difference was detected in the left ventricular ejection fraction between the control and the diabetic group(P>0.05),while differences in global longitudinal strain,global circumferential strain,global radial strain,and global area strain were markedly different between the controls and DM patients(all P<0.05).CONCLUSION The 3D-STI could be applied to accurately measure early LVSF damage in patients with DM.

Fixed-Time Antidisturbance Consensus Tracking for Nonlinear Multiagent Systems With Matching and Mismatching Disturbances

In this paper,fixed-time consensus tracking for mul-tiagent systems(MASs)with dynamics in the form of strict feed-back affine nonlinearity is addressed.A fixed-time antidistur-bance consensus tracking protocol is proposed,which consists of a distributed fixed-time observer,a fixed-time disturbance observer,a nonsmooth antidisturbance backstepping controller,and the fixed-time stability analysis is conducted by using the Lyapunov theory correspondingly.This paper includes three main improvements.First,a distributed fixed-time observer is developed for each follower to obtain an estimate of the leader’s output by utilizing the topology of the communication network.Second,a fixed-time disturbance observer is given to estimate the lumped disturbances for feedforward compensation.Finally,a nonsmooth antidisturbance backstepping tracking controller with feedforward compensation for lumped disturbances is designed.In order to mitigate the“explosion of complexity”in the tradi-tional backstepping approach,we have implemented a modified nonsmooth command filter to enhance the performance of the closed-loop system.The simulation results show that the pro-posed method is effective.

Stabilization and trajectory tracking of autonomous airship's planar motion

The stabilization and trajectory tracking problems of autonomous airship＇s planar motion are studied. By defining novel configuration error and velocity error, the dynamics of error systems are derived. By applying Lyapunov stability method, the state feedback control laws are designed and the close-loop error systems are proved to be uniformly asymptotically stable by Matrosov theorem. In particular, the controller does not need knowledge on system parameters in the case of set-point stabilization, which makes the controller robust with respect to parameter uncertainty. Numerical simulations illustrate the effectiveness of the controller designed.

Electronic image stabilization system based on global feature tracking

A new robust electronic image stabilization system is presented, which involves feature-point, tracking based global motion estimation and Kalman filtering based motion compensation. First, global motion is estimated from the local motions of selected feature points. Considering the local moving objects or the inevitable mismatch, the matching validation, based on the stable relative distance between the points set is proposed, thus maintaining high accuracy and robustness. Next, the global motion parameters are accumulated for correction by Kalman filteration. The experimental result illustrates that the proposed system is effective to stabilize translational, rotational, and zooming jitter and robust to local motions.

Three-dimensional mesoscale eddy identification and tracking algorithm based on pressure anomalies Liming

The Kuroshio Extension(KE)is one of the most eddy-energetic regions in the global ocean.However,most mesoscale eddy studies in the region are focused on surface eddies and the structure and characteristics of three-dimensional(3-D)eddies require additional research.In this study,we proposed a 3-D eddy identification and tracking algorithm based on pressure anomalies,similar to sea level anomalies(SLAs)for surface eddy identification.We applied this scheme to a 5-year(2008-2012)high-resolution numerical product to develop a 3-D eddy dataset in the KE.The reliability of the numerical product was verified by the 5-year temperature/salinity hydrological characteristics and surface eddy distribution.According to the 3-D eddy tracking dataset,the number of eddies decreased dramatically as the eddy existence-time increased and more anticyclonic eddies(AEs)had an existence-time longer than 1 week than cyclonic eddies(CEs).We presented daily variations in the 3-D structure of two 3-D eddy-tracking trajectories that exhibit a certain jump in depth and a shift toward the west and equator.In addition to the bowl,lens,and cone eddies that have been discovered by previous researchers,we found that there is a cylindrical eddy,and its eddy radii are almost consistent across all layers.CEs cause significant negative temperature anomalies,“negative-positive”salinity anomalies,and sinking current fields in the KE region,while AEs cause positive temperature anomalies,“positive-negative”salinity anomalies,and upward current fields.The four types of eddies have different effects on the temperature/salinity anomalies and current field distribution which are related to their structure.

Left Ventricular Systolic Strain of the Cardiac Allograft Evaluated with Three-dimensional Speckle Tracking Echocardiography

Three-dimensional speckle tracking echocardiography was employed to evaluate the changes of left ventricular systolic strain in 23 heart transplant recipients at 1 st, 3rd, 6th and 12th month after heart transplantation, and 23 healthy subjects served as controls. The three-dimensional full-volume echocardiographic images of left ventricle were recorded and then were analyzed using EchoPAC software. The strain curves and peak systolic strain values for each segment and overall left ventricular wall were obtained. Left ventricular global peak longitudinal strain （GPSL）, global peak radial strain （GPSR）, global peak circumferential strain （GPSC） and global peak area strain （GPSA） were measured and then statistically analyzed. There were no significant differences in left ventricular ejection fraction （LVEF） and cardiac output （CO） between heart transplant recipients and controls. The GPSL in heart transplant recipients at 1st month after surgery was significantly lower than that in controls, but close to the normal value at 3rd month after surgery and later. The GPSC, GPSA and GPSR were significantly lower in heart transplant recipients at 1 st, 3rd, 6th and 12th month after surgery than those in controls. It is suggested that three-dimensional speckle tracking echocardiography can be used for monitoring changes of left ventricular systolic strains and evaluating left ventricular systolic function in cardiac allograft.

STABILIZATION EFFECT OF FRICTIONS FOR TRANSONIC SHOCKS IN STEADY COMPRESSIBLE EULER FLOWS PASSING THREE-DIMENSIONAL DUCTS

Transonic shocks play a pivotal role in designation of supersonic inlets and ramjets.For the three-dimensional steady non-isentropic compressible Euler system with frictions,we constructe a family of transonic shock solutions in rectilinear ducts with square cross-sections.In this article,we are devoted to proving rigorously that a large class of these transonic shock solutions are stable,under multidimensional small perturbations of the upcoming supersonic flows and back pressures at the exits of ducts in suitable function spaces.This manifests that frictions have a stabilization effect on transonic shocks in ducts,in consideration of previous works which shown that transonic shocks in purely steady Euler flows are not stable in such ducts.Except its implications to applications,because frictions lead to a stronger coupling between the elliptic and hyperbolic parts of the three-dimensional steady subsonic Euler system,we develop the framework established in previous works to study more complex and interesting Venttsel problems of nonlocal elliptic equations.

Value of myocardial function in children with Kawasaki disease by two-dimensional and three-dimensional ultrasound speckle tracking

Objective:To investigate the value of two-dimensional ultrasound speckle tracking(2D-STI)and three-dimensional ultrasound speckle tracking(3D-STI)in evaluating myocardial function in children with Kawasaki disease.Methods 92 children with Kawasaki disease admitted to our hospital from February 2017 to February 2019 were retrospectively analyzed.50 children who underwent 3D-STI examination were taken as observation group and 42 children who underwent 2D-STI examination were taken as control group.The left ventricular systolic function index,storage time and analysis time of the image,the diameter of coronary artery,the strain difference of left ventricular basal segment,middle segment,apical segment and whole segment were observed.Results The levels of left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),left ventricular myocardial mass(LVMI)in the observation group were higher than those in the control group(P<0.05),but there was no statistical difference in left ventricular ejection fraction(LVEF)between the two groups(P>0.05).The storage time and analysis time of the image in the observation group were significantly lower than those in the control group(P<0.05).The left coronary artery(LCA)and right coronary artery(RCA)in the observation group were higher than those in the control group(P<0.05).There was no statistical difference between left anterior descending(LAD)in the two groups(P>0.05).The longitudinal peak systolic strain(LS),circumferential peak systolic strain(CS)and radial peak systolic strain(RS)in the observation group were higher than those in the control group(P<0.05).The global longitudinal peak strain(GLS),global circumferential peak strain(GCS)and global radial peak strain(GRS)in the observation group were higher than those in the control group(P<0.05).LS and CS in the middle segment of the observation group were higher than those in the control group(P<0.05).Conclusions Compared with 2D-STI,3D-STI can objectively and accurately reflect the myocardial function of children with Kawasaki disease.

Correlation between three-dimensional speckle tracking imaging parameter and the cardiotoxicity of chemotherapeutics in patients with lung cancer chemotherapy

Objective: To study the correlation between three-dimensional speckle tracking imaging (3D-STI) parameter global area strain (GAS) and the cardiotoxicity of chemotherapeutics in patients with lung cancer chemotherapy. Methods: Patients with lung cancer who underwent chemotherapy in the Second Affiliated Hospital of Xi'an Medical University between February 2016 and May 2017 were selected as the chemotherapy group, the healthy subjects who received physical examination during the same period were selected as the control group, the 3D-STI examination was performed and GAS was calculated;the serum was collected to determine the contents of cardiotoxicity markers as well as apoptosis and oxidative stress indexes, and the peripheral blood was collected to determine the expression of apoptosis and oxidative stress molecules. Results: GAS level, serum ALDH2 and CAT contents as well as peripheral blood Keap1 and Bcl-2 expression intensity of chemotherapy group were lower than those of control group whereas serum Copeptin, CK-MB, cTnI, cMyBP-c, sTWEAK, sFas, MDA and 8-isoPGF2α contents as well as peripheral blood Nrf-2, gp91phox, p22 phox and Caspase-3 expression intensity were significantly higher than those of control group;the GAS level in chemotherapy group was negatively correlated with serum Copeptin, CK-MB, cTnI, cMyBP-c, sTWEAK, sFas, MDA and 8-isoPGF2α contents as well as peripheral blood Nrf-2, gp91phox, p22 phox and Caspase-3 expression intensity, and positively correlated with serum ALDH2 and CAT contents as well as peripheral blood Keap1 and Bcl-2 expression intensity. Conclusion: The changes of 3D-STI parameter GAS in patients with lung cancer chemotherapy can reflect the degree of cardiotoxicity induced by oxidative stress and apoptosis.

Correlation between three-dimensional speckle tracking parameters and serum index changes during left ventricular remodeling in patients with coronary heart disease

Objective:To study the correlation between three-dimensional speckle tracking parameters and serum index changes during left ventricular remodeling in patients with coronary heart disease. Methods: Patients who were diagnosed with coronary heart disease and angina pectoris in our hospital between March 2015 and May 2017 were selected as the CHD group of the study, and the healthy subjects who received medical examination in our hospital during the same period were taken as the control group;the three-dimensional speckle tracking parameters, peripheral blood signal molecule expression as well as serum cytokine and collagen metabolism index levels of the two groups were measured.Results: GLS and AGS levels in CHD group were significantly lower than those in control group whereas GCS and GRS levels were not significantly different from those in control group, and peripheral blood Notch1, Hes1, NF-κB and PKC expression intensity as well as serum sTWEAK, FGF23, TGF-β1, GDF15, sSema4D, CaN, MMP14, PINP and ICTP contents were significantly higher than those of control group;GLS and AGS levels in CHD group were negatively correlated with peripheral blood Notch1, Hes1, NF-κB and PKC expression intensity as well as serum sTWEAK, FGF23, TGF-β1, GDF15, sSema4D, CaN, MMP14, PINP and ICTP contents.Conclusions:The changes of three-dimensional speckle tracking parameters GLS and AGS in patients with coronary heart disease are closely related to the changes in signal pathway function, cytokine secretion and collagen metabolism during left ventricular remodeling.

Backstepping Based Global Exponential Stabilization of a Tracked Mobile Robot with Slipping Perturbation

While the nonholonomic robots with no-slipping constraints are studied extensively nowadays, the slipping effect is inevitable in many practical applications and should be considered necessarily to achieve autonomous navigation and control purposes especially in outdoor environments. In this paper the robust point stabilization problem of a tracked mobile robot is discussed in the presence of track slipping, which can be treated as model perturbation that violates the pure nonholonomic constraints. The kinematic model of the tracked vehicle is created, in which the slipping is assumed to be a time-varying pa- rameter under certain assumptions of track-soil interaction. By transforming the original system to the special chained form of nonholonomic system, the integrator backstepping procedure with a state-scaling technique is used to construct the controller to stabilize the system at the kinematic level. The global exponential stability of the final system can be guaranteed by Lyapunov theory. Simulation results with different initial states and slipping parameters demonstrate the fast convergence, robustness and insensitivity to the initial state of the proposed method.

Limit analysis for the seismic stability of three-dimensional rock slopes using the generalized Hoek-Brown criterion

The parameters that influence slope stability and their criteria of failure are fairly understood but over-conservative design approaches are often preferred,which can result in excessive overburden removal that may jeopardize profitability in the context of open pit mining.Numerical methods such as finite element and discrete element modelling are instrumental to identify specific zones of stability,but they remain approximate and do not pinpoint the critical factors that influence stability without extensive parametric studies.A large number of degrees of freedom and input parameters may make the outcome of numerical modelling insufficient compared to analytical solutions.Existing analytical approaches have not tackled the stability of slopes using non-linear plasticity criteria and threedimensional failure mechanisms.This paper bridges this gap by using the yield design theory and the Hoek-Brown criterion.Moreover,the proposed model includes the effect of seismic forces,which are not always taken into account in slope stability analyses.The results are presented in the form of rigorous mathematical expressions and stability charts involving the loading conditions and the rock mass properties emanating from the plasticity criterion.

Three-dimensional mixed convection stagnation-point fow past a vertical surface with second-order slip velocity

This study is concerned with the three-dimensional(3D)stagnation-point for the mixed convection flow past a vertical surface considering the first-order and secondorder velocity slips.To the authors’knowledge,this is the first study presenting this very interesting analysis.Nonlinear partial differential equations for the flow problem are transformed into nonlinear ordinary differential equations(ODEs)by using appropriate similarity transformation.These ODEs with the corresponding boundary conditions are numerically solved by utilizing the bvp4c solver in MATLAB programming language.The effects of the governing parameters on the non-dimensional velocity profiles,temperature profiles,skin friction coefficients,and the local Nusselt number are presented in detail through a series of graphs and tables.Interestingly,it is reported that the reduced skin friction coefficient decreases for the assisting flow situation and increases for the opposing flow situation.The numerical computations of the present work are compared with those from other research available in specific situations,and an excellent consensus is observed.Another exciting feature for this work is the existence of dual solutions.An important remark is that the dual solutions exist for both assisting and opposing flows.A linear stability analysis is performed showing that one solution is stable and the other solution is not stable.We notice that the mixed convection and velocity slip parameters have strong effects on the flow characteristics.These effects are depicted in graphs and discussed in this paper.The obtained results show that the first-order and second-order slip parameters have a considerable effect on the flow,as well as on the heat transfer characteristics.

Discounted Iterative Adaptive Critic Designs With Novel Stability Analysis for Tracking Control

The core task of tracking control is to make the controlled plant track a desired trajectory.The traditional performance index used in previous studies cannot eliminate completely the tracking error as the number of time steps increases.In this paper,a new cost function is introduced to develop the value-iteration-based adaptive critic framework to solve the tracking control problem.Unlike the regulator problem,the iterative value function of tracking control problem cannot be regarded as a Lyapunov function.A novel stability analysis method is developed to guarantee that the tracking error converges to zero.The discounted iterative scheme under the new cost function for the special case of linear systems is elaborated.Finally,the tracking performance of the present scheme is demonstrated by numerical results and compared with those of the traditional approaches.

Criteria for the Nonlinear Stability of Three-Dimensional Quasi-Geostrophic Motions

Some more proper criteria for the nonlinear stability of three-dimensional quasi-geostrophic motions are given by combining variational principle with a prior estimates method. The criteria are suitable for perturbations of initial condition as well as parameters in the model. The basic flow can be steady or unsteady. Particularly the difficulty due to the nonlinear boundary condition is completely overcome by the use of our method.

Undrained Stability Analysis of Three-Dimensional Rectangular Trapdoor in Clay

A new collapse model of the trapdoors,three-dimensional rectangular trapdoor(3DRT),is presented for ground surface collapse.Undrained stability of 3DRT is examined with the upper bound method of plasticity limit analysis theory.The soil where the trapdoors are located is assumed to be a perfectly plastic model with a Tresca yield criterion.Block analysis technique is employed to investigate the collapse of 3DRT.The model is divided into five different block types and added up to ten rigid blocks.According to the law of conservation of energy,the critical stability ratios of 3DRT are obtained through a search proceeding.The results of upper bound solution for 3DRT are given,and three trapdoor models with depth various are discussed during the application in the stability analysis of square trapdoors.The critical stability ratios can be used in the design of underground excavation and support force.

Three-dimensional critical slip surface locating and slope stability assessment for lava lobe of Unzen volcano

Even Unzen volcano has been declared to be in a state of relative dormancy,the latest formed lava lobe No.11 now represents a potential slope failure mass based on the latest research.This paper concentrates on the stability of the lava lobe No.11 and its possible critical sliding mass.It proposes geographic information systems (GIS) based three-dimensional (3D) slope stability analysis models.It uses a 3D locating approach to identify the 3D critical slip surface and to analyze the 3D stability of the lava lobe No.11.At the same time,the new 3D approach shows the effectiveness in selecting the range of the Monte Carlo random variables and locating the critical slip surface in different parts of the lava lobe No.11.The results are very valuable for judging the stability of the lava lobe and assigning the monitoring equipments.

Nonlinear Stability of Plane Rotating Shear Flow under Three-Dimensional Nondivergence Disturbances

Nonlinear stability criterion for plane rotating shear flow under three-dimensional nondivergence disturbances was obtained by using both variational principle and convexity estimate introduced by Arnold (1965) and Holm et al. (1985). The results obtained in this paper show that the effect of Coriolis force plays an important role in the nonlinear stability criterion, and the nonlinear stability property of the basic flow depends on both the distribution of basic states and the way the external disturbance acts on the states. The upper bound of the gradient of the mass density displacement from the equilibrium k2 = is determined by the basic states and one example was given to show the exact upper value of k. The remarks on Blumen's paper were also given at Section 4 of this paper.

Robust adaptive tracking control of robotic systems with uncertainties

To deal with the uncertainty factors of robotic systems, a robust adaptive tracking controller is proposed. The knowledge of the uncertainty factors is assumed to be unidentified; the proposed controller can guarantee robustness to parametric and dynamics uncertainties and can also reject any bounded, immeasurable disturbances entering the system. The stability of the proposed controller is proven by the Lyapunov method. The proposed controller can easily be implemented and the stability of the closed system can be ensured; the tracking error and adaptation parameter error are uniformly ultimately bounded （UUB）. Finally, some simulation examples are utilized to illustrate the control performance.

Current trends in three-dimensional visualization and real-time navigation as well as robot-assisted technologies in hepatobiliary surgery

With the continuous development of digital medicine,minimally invasive precision and safety have become the primary development trends in hepatobiliary surgery.Due to the specificity and complexity of hepatobiliary surgery,traditional preoperative imaging techniques such as computed tomography and magnetic resonance imaging cannot meet the need for identification of fine anatomical regions.Imaging-based three-dimensional(3D)reconstruction,virtual simulation of surgery and 3D printing optimize the surgical plan through preoperative assessment,improving the controllability and safety of intraoperative operations,and in difficult-to-reach areas of the posterior and superior liver,assistive robots reproduce the surgeon’s natural movements with stable cameras,reducing natural vibrations.Electromagnetic navigation in abdominal surgery solves the problem of conventional surgery still relying on direct visual observation or preoperative image assessment.We summarize and compare these recent trends in digital medical solutions for the future development and refinement of digital medicine in hepatobiliary surgery.